3MDDA

Crystal structures of medium chain acyl-coa dehydrogenase from pig liver mitochondria with and without substrate
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
385
structure length
385
Chain Sequence
GFSFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESFGGLGLGIIDSCLITEELAYGCTGVQTAIEANTLGQVPLIIGGNYQQQKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPASKAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKIAMGTFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELARLSYQRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDAKIYQIYEGTAQIQRIIIAREHIGRYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords MEDIUM CHAIN ACYL-COA DEHYDROGENASE
publication title Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate.
pubmed doi rcsb
source organism Sus scrofa
molecule tags Oxidoreductase
total genus 145
structure length 385
sequence length 385
chains with identical sequence B
ec nomenclature ec 1.3.8.7: Medium-chain acyl-CoA dehydrogenase.
pdb deposition date 1994-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3mddA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3mddA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3mddA02
4L3ZA 3II9A 1IS2A 4JEKA 4O5MA 3OIBA 1SIRA 2IX5A 3D9DA 5K3HA 4IV6A 1OAHA 3D9FA 4KTOA 3OWAA 1FS9A 4OO2A 4P13A 1SIQA 3GNCA 3GM6A 1EGDA 4Q1OA 2Z1QA 2RDZA 3HWCA 2E80A 3TTBA 2DVLA 2UXWA 2OT4A 4L3YA 2RFQA 3LGQA 3S7WA 3BNJA 3TORA 2ZO5A 2YYGA 2CX9A 3FO3A 2J7AA 2PG0A 4U83A 3M9VA 3SF6A 3X0XA 2VR0A 4Q4UA 4Q0TA 3MPIA 2EBAA 4RM7A 3BNGA 3SXQA 2YYLA 2FONA 2YYKA 2R0MA 3EONA 1T9GA 3AFEA 2VIGA 2YYIA 3AFFA 3SCEA 4M9AA 4X28A 3FCJA 2WBIA 4NXLA 1JQIA 1FS7A 1UDYA 2IX6A 4HR3A 1BUCA 5K3IA 3PFDA 3RKHA 2DDHA 2C0UA 4Q17A 2YYMA 4L3XA 3D6BA 3MMOA 1EGEA 4ZXVA 5K3GA 1UKWA 3BNFA 4L38A 2RF7A 2OR0A 1QDBA 1GU6A 3R7KA 3D9GA 2A1TA 4L1FA 4G5EA 3P4TA 1IVHA 2REHA 3SWOA 2JBRA 1RX0A 4X28C 3D1IA 4Q5CA 3OWMA 3B96A 2JBTA 2JIFA 2JBSA 2D29A 3EOMA 3MXLA 1EGCA 4N5FA 3UBRA 2ZAFA 4ZYJA 4W9UA 3LG1A 3GQTA 1U8VA 3MKHA 2E81A 3NF4A 1FS8A 4IRNA 1WS9A 3BNHA 4Q5BA 3MPJA 3MDEA 3X0YA 4DOYA 2YYJA 4XVXA 2C12A 5K3JA 4KCFA 2R0NA 3L1TA 4WJYA 1R2JA 3UU9A 3MDDA 1W07A 3F29A 3D9EA
chains in the Genus database with same CATH superfamily
2BTZA 4L3ZA 3II9A 2Q8IA 5J71A 4KSFA 2CJ6A 1IS2A 4JEKA 4O5MA 3OIBA 4FF3A 1SIRA 2IX5A 3D9DA 5K3HA 3CRKA 4IV6A 1OAHA 3D9FA 4KTOA 2VF1A 3OWAA 1FS9A 2ZKJA 4LQQB 4OO2A 4P13A 1SIQA 3GNCA 1X91A 1EGDA 3GM6A 3TZ2A 4MP2A 4Q1OA 4MPNA 2Z1QA 2RDZA 3HWCA 5EZ3A 4JIZA 4MPCA 4H7QA 2PO4A 2AO2A 2E80A 3TTBA 2DVLA 1X8ZA 2UXWA 3X29A 2OT4A 3VKGA 4L3YA 2RFQA 3C46A 3LGQA 3N0RA 3S7WA 3BNJA 2PNRA 3TORA 5M4NA 2ZO5A 5GJWE 2YYGA 2Q8HA 2AZEA 3CE2A 1X90A 2Q8FA 1XFXA 5B6BA 2CX9A 5GJVE 3FO3A 3Q22A 2J7AA 4KSAA 2PG0A 4U83A 3M9VA 3SF6A 1GJVA 3X0XA 1XFVA 2VR0A 4Q4UA 3Q0AA 4Q0TA 3MPIA 4V25A 2EBAA 4RM7A 2XS1A 3BNGA 1S26A 1GKZA 3SXQA 2YYLA 2FONA 2EC5A 2YYKA 5M4MA 2R0MA 3EONA 1T9GA 3AFEA 2FP1A 4JIOA 4AKIA 4FZ4A 2VIGA 4FF4A 2GBBA 2YGWA 1Y8NA 2BU2A 3AFFA 2CJ8A 2YYIA 3SCEA 2CJ4A 2OJQA 4AKGA 1RJ1A 4DZYA 4M9AA 4X28A 3FCJA 2WBIA 4NXLA 1JQIA 1FS7A 1UDYA 1K90A 1Y0VA 2EBFX 2IX6A 4HR3A 2ZDXA 1BUCA 5K3IA 3PFDA 1PK0A 2DDHA 3RKHA 4AKHA 2C0UA 4Q17A 1RP3A 1GKXA 3C2PA 2YYMA 4L3XA 2BU5A 3D6BA 3TZ0A 2R02A 1JM6A 2BU6A 3MMOA 4G97A 4MP7A 1EGEA 5B5WA 4ZXVA 5M4KA 1XFUA 5K3GA 1XG2B 2F6LA 1UKWA 2OEVA 3BNFA 4L38A 1XFZA 2RF7A 5BRKA 2EBHX 2OR0A 1QDBA 4FF1A 4HKSA 3CRLA 1GU6A 5J6AA 3R7KA 2LFWA 2Q8GA 2R03A 3D9GA 2CJ7A 5M4PA 4V26A 2XS8A 1K93A 2R05A 2A1TA 4L1FA 4G5EA 3VKHA 3P4TA 1IVHA 3KMLA 2REHA 2ZDYA 3SWOA 2XQRB 2CJ5A 2JBRA 1RX0A 4X28C 2QR4A 3D1IA 4Q5CA 3OWMA 3B96A 1XFWA 2JBTA 2HJNA 4QICA 2JIFA 4MPEA 4FF2A 3TZ5A 2JBSA 2D29A 1PI1A 3Q24A 3EOMA 3C3LA 3MXLA 1LVCA 1K8TA 4E01A 1EGCA 4N5FA 2BU8A 2OEXA 2ZAFA 4ZYJA 4W9UA 3LG1A 5BRMA 3GQTA 1U8VA 3UBRA 3TZ4A 3MKHA 2E81A 4E02A 3NF4A 3Q23A 1FS8A 4IRNA 1Y8OA 1WS9A 2BU7A 3BNHA 1SC5A 4HKRA 4Q5BA 2FP2A 3MPJA 3MDEA 1XFYA 3VADA 4H81A 4LQSB 3DJLA 3U33A 3X0YA 4DOYA 2YYJA 4XVXA 2C12A 5K3JA 1SK6A 4KCFA 2E0AA 3D2RA 4P79A 2R0NA 3L1TA 4WJYA 4KS9A 4AI6A 1Y8PA 1R2JA 4H85A 3UU9A 3MDDA 1R3BA 4J1VA 5B5VA 1RJ4A 1W07A 3F29A 4E00A 4F0XA 3D9EA
chains in the Genus database with same CATH topology
4L3ZA 3II9A 1IS2A 4JEKA 4O5MA 3OIBA 1SIRA 2IX5A 3D9DA 5K3HA 4IV6A 1OAHA 3D9FA 4KTOA 3OWAA 1FS9A 4OO2A 4P13A 1SIQA 3GNCA 3GM6A 1EGDA 4Q1OA 2Z1QA 2RDZA 3HWCA 2E80A 3TTBA 2DVLA 2UXWA 2OT4A 4L3YA 2RFQA 3LGQA 3S7WA 3BNJA 3TORA 2ZO5A 2YYGA 2CX9A 3FO3A 2J7AA 2PG0A 4U83A 3M9VA 3SF6A 3X0XA 2VR0A 4Q4UA 4Q0TA 3MPIA 2EBAA 4RM7A 3BNGA 3SXQA 2YYLA 2FONA 2YYKA 2R0MA 3EONA 1T9GA 3AFEA 2VIGA 2YYIA 3AFFA 3SCEA 4M9AA 4X28A 3FCJA 2WBIA 4NXLA 1JQIA 1FS7A 1UDYA 2IX6A 4HR3A 1BUCA 5K3IA 3PFDA 3RKHA 2DDHA 2C0UA 4Q17A 2YYMA 4L3XA 3D6BA 3MMOA 1EGEA 4ZXVA 5K3GA 1UKWA 3BNFA 4L38A 2RF7A 2OR0A 1QDBA 1GU6A 3R7KA 3D9GA 2A1TA 4L1FA 4G5EA 3P4TA 1IVHA 2REHA 3SWOA 2JBRA 1RX0A 4X28C 3D1IA 4Q5CA 3OWMA 3B96A 2JBTA 2JIFA 2JBSA 2D29A 3EOMA 3MXLA 1EGCA 4N5FA 3UBRA 2ZAFA 4ZYJA 4W9UA 3LG1A 3GQTA 1U8VA 3MKHA 2E81A 3NF4A 1FS8A 4IRNA 1WS9A 3BNHA 4Q5BA 3MPJA 3MDEA 3X0YA 4DOYA 2YYJA 4XVXA 2C12A 5K3JA 4KCFA 2R0NA 3L1TA 4WJYA 1R2JA 3UU9A 3MDDA 1W07A 3F29A 3D9EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L3Z A;  3II9 A;  1IS2 A;  4JEK A;  4O5M A;  3OIB A;  1SIR A;  2IX5 A;  3D9D A;  5K3H A;  4IV6 A;  1OAH A;  3D9F A;  4KTO A;  3OWA A;  1FS9 A;  4OO2 A;  4P13 A;  1SIQ A;  3GNC A;  3GM6 A;  1EGD A;  4Q1O A;  2Z1Q A;  2RDZ A;  3HWC A;  2E80 A;  3TTB A;  2DVL A;  2UXW A;  2OT4 A;  4L3Y A;  2RFQ A;  3LGQ A;  3S7W A;  3BNJ A;  3TOR A;  2ZO5 A;  2YYG A;  2CX9 A;  3FO3 A;  2J7A A;  2PG0 A;  4U83 A;  3M9V A;  3SF6 A;  3X0X A;  2VR0 A;  4Q4U A;  4Q0T A;  3MPI A;  2EBA A;  4RM7 A;  3BNG A;  3SXQ A;  2YYL A;  2FON A;  2YYK A;  2R0M A;  3EON A;  1T9G A;  3AFE A;  2VIG A;  2YYI A;  3AFF A;  3SCE A;  4M9A A;  4X28 A;  3FCJ A;  2WBI A;  4NXL A;  1JQI A;  1FS7 A;  1UDY A;  2IX6 A;  4HR3 A;  1BUC A;  5K3I A;  3PFD A;  3RKH A;  2DDH A;  2C0U A;  4Q17 A;  2YYM A;  4L3X A;  3D6B A;  3MMO A;  1EGE A;  4ZXV A;  5K3G A;  1UKW A;  3BNF A;  4L38 A;  2RF7 A;  2OR0 A;  1QDB A;  1GU6 A;  3R7K A;  3D9G A;  2A1T A;  4L1F A;  4G5E A;  3P4T A;  1IVH A;  2REH A;  3SWO A;  2JBR A;  1RX0 A;  4X28 C;  3D1I A;  4Q5C A;  3OWM A;  3B96 A;  2JBT A;  2JIF A;  2JBS A;  2D29 A;  3EOM A;  3MXL A;  1EGC A;  4N5F A;  3UBR A;  2ZAF A;  4ZYJ A;  4W9U A;  3LG1 A;  3GQT A;  1U8V A;  3MKH A;  2E81 A;  3NF4 A;  1FS8 A;  4IRN A;  1WS9 A;  3BNH A;  4Q5B A;  3MPJ A;  3MDE A;  3X0Y A;  4DOY A;  2YYJ A;  4XVX A;  2C12 A;  5K3J A;  4KCF A;  2R0N A;  3L1T A;  4WJY A;  1R2J A;  3UU9 A;  3MDD A;  1W07 A;  3F29 A;  3D9E A; 
#chains in the Genus database with same CATH topology
 2BTZ A;  4L3Z A;  3II9 A;  2Q8I A;  5J71 A;  4KSF A;  2CJ6 A;  1IS2 A;  4JEK A;  4O5M A;  3OIB A;  4FF3 A;  1SIR A;  2IX5 A;  3D9D A;  5K3H A;  3CRK A;  4IV6 A;  1OAH A;  3D9F A;  4KTO A;  2VF1 A;  3OWA A;  1FS9 A;  2ZKJ A;  4LQQ B;  4OO2 A;  4P13 A;  1SIQ A;  3GNC A;  1X91 A;  1EGD A;  3GM6 A;  3TZ2 A;  4MP2 A;  4Q1O A;  4MPN A;  2Z1Q A;  2RDZ A;  3HWC A;  5EZ3 A;  4JIZ A;  4MPC A;  4H7Q A;  2PO4 A;  2AO2 A;  2E80 A;  3TTB A;  2DVL A;  1X8Z A;  2UXW A;  3X29 A;  2OT4 A;  3VKG A;  4L3Y A;  2RFQ A;  3C46 A;  3LGQ A;  3N0R A;  3S7W A;  3BNJ A;  2PNR A;  3TOR A;  5M4N A;  2ZO5 A;  5GJW E;  2YYG A;  2Q8H A;  2AZE A;  3CE2 A;  1X90 A;  2Q8F A;  1XFX A;  5B6B A;  2CX9 A;  5GJV E;  3FO3 A;  3Q22 A;  2J7A A;  4KSA A;  2PG0 A;  4U83 A;  3M9V A;  3SF6 A;  1GJV A;  3X0X A;  1XFV A;  2VR0 A;  4Q4U A;  3Q0A A;  4Q0T A;  3MPI A;  4V25 A;  2EBA A;  4RM7 A;  2XS1 A;  3BNG A;  1S26 A;  1GKZ A;  3SXQ A;  2YYL A;  2FON A;  2EC5 A;  2YYK A;  5M4M A;  2R0M A;  3EON A;  1T9G A;  3AFE A;  2FP1 A;  4JIO A;  4AKI A;  4FZ4 A;  2VIG A;  4FF4 A;  2GBB A;  2YGW A;  1Y8N A;  2BU2 A;  3AFF A;  2CJ8 A;  2YYI A;  3SCE A;  2CJ4 A;  2OJQ A;  4AKG A;  1RJ1 A;  4DZY A;  4M9A A;  4X28 A;  3FCJ A;  2WBI A;  4NXL A;  1JQI A;  1FS7 A;  1UDY A;  1K90 A;  1Y0V A;  2EBF X;  2IX6 A;  4HR3 A;  2ZDX A;  1BUC A;  5K3I A;  3PFD A;  1PK0 A;  2DDH A;  3RKH A;  4AKH A;  2C0U A;  4Q17 A;  1RP3 A;  1GKX A;  3C2P A;  2YYM A;  4L3X A;  2BU5 A;  3D6B A;  3TZ0 A;  2R02 A;  1JM6 A;  2BU6 A;  3MMO A;  4G97 A;  4MP7 A;  1EGE A;  5B5W A;  4ZXV A;  5M4K A;  1XFU A;  5K3G A;  1XG2 B;  2F6L A;  1UKW A;  2OEV A;  3BNF A;  4L38 A;  1XFZ A;  2RF7 A;  5BRK A;  2EBH X;  2OR0 A;  1QDB A;  4FF1 A;  4HKS A;  3CRL A;  1GU6 A;  5J6A A;  3R7K A;  2LFW A;  2Q8G A;  2R03 A;  3D9G A;  2CJ7 A;  5M4P A;  4V26 A;  2XS8 A;  1K93 A;  2R05 A;  2A1T A;  4L1F A;  4G5E A;  3VKH A;  3P4T A;  1IVH A;  3KML A;  2REH A;  2ZDY A;  3SWO A;  2XQR B;  2CJ5 A;  2JBR A;  1RX0 A;  4X28 C;  2QR4 A;  3D1I A;  4Q5C A;  3OWM A;  3B96 A;  1XFW A;  2JBT A;  2HJN A;  4QIC A;  2JIF A;  4MPE A;  4FF2 A;  3TZ5 A;  2JBS A;  2D29 A;  1PI1 A;  3Q24 A;  3EOM A;  3C3L A;  3MXL A;  1LVC A;  1K8T A;  4E01 A;  1EGC A;  4N5F A;  2BU8 A;  2OEX A;  2ZAF A;  4ZYJ A;  4W9U A;  3LG1 A;  5BRM A;  3GQT A;  1U8V A;  3UBR A;  3TZ4 A;  3MKH A;  2E81 A;  4E02 A;  3NF4 A;  3Q23 A;  1FS8 A;  4IRN A;  1Y8O A;  1WS9 A;  2BU7 A;  3BNH A;  1SC5 A;  4HKR A;  4Q5B A;  2FP2 A;  3MPJ A;  3MDE A;  1XFY A;  3VAD A;  4H81 A;  4LQS B;  3DJL A;  3U33 A;  3X0Y A;  4DOY A;  2YYJ A;  4XVX A;  2C12 A;  5K3J A;  1SK6 A;  4KCF A;  2E0A A;  3D2R A;  4P79 A;  2R0N A;  3L1T A;  4WJY A;  4KS9 A;  4AI6 A;  1Y8P A;  1R2J A;  4H85 A;  3UU9 A;  3MDD A;  1R3B A;  4J1V A;  5B5V A;  1RJ4 A;  1W07 A;  3F29 A;  4E00 A;  4F0X A;  3D9E A; 
#chains in the Genus database with same CATH homology
 4L3Z A;  3II9 A;  1IS2 A;  4JEK A;  4O5M A;  3OIB A;  1SIR A;  2IX5 A;  3D9D A;  5K3H A;  4IV6 A;  1OAH A;  3D9F A;  4KTO A;  3OWA A;  1FS9 A;  4OO2 A;  4P13 A;  1SIQ A;  3GNC A;  3GM6 A;  1EGD A;  4Q1O A;  2Z1Q A;  2RDZ A;  3HWC A;  2E80 A;  3TTB A;  2DVL A;  2UXW A;  2OT4 A;  4L3Y A;  2RFQ A;  3LGQ A;  3S7W A;  3BNJ A;  3TOR A;  2ZO5 A;  2YYG A;  2CX9 A;  3FO3 A;  2J7A A;  2PG0 A;  4U83 A;  3M9V A;  3SF6 A;  3X0X A;  2VR0 A;  4Q4U A;  4Q0T A;  3MPI A;  2EBA A;  4RM7 A;  3BNG A;  3SXQ A;  2YYL A;  2FON A;  2YYK A;  2R0M A;  3EON A;  1T9G A;  3AFE A;  2VIG A;  2YYI A;  3AFF A;  3SCE A;  4M9A A;  4X28 A;  3FCJ A;  2WBI A;  4NXL A;  1JQI A;  1FS7 A;  1UDY A;  2IX6 A;  4HR3 A;  1BUC A;  5K3I A;  3PFD A;  3RKH A;  2DDH A;  2C0U A;  4Q17 A;  2YYM A;  4L3X A;  3D6B A;  3MMO A;  1EGE A;  4ZXV A;  5K3G A;  1UKW A;  3BNF A;  4L38 A;  2RF7 A;  2OR0 A;  1QDB A;  1GU6 A;  3R7K A;  3D9G A;  2A1T A;  4L1F A;  4G5E A;  3P4T A;  1IVH A;  2REH A;  3SWO A;  2JBR A;  1RX0 A;  4X28 C;  3D1I A;  4Q5C A;  3OWM A;  3B96 A;  2JBT A;  2JIF A;  2JBS A;  2D29 A;  3EOM A;  3MXL A;  1EGC A;  4N5F A;  3UBR A;  2ZAF A;  4ZYJ A;  4W9U A;  3LG1 A;  3GQT A;  1U8V A;  3MKH A;  2E81 A;  3NF4 A;  1FS8 A;  4IRN A;  1WS9 A;  3BNH A;  4Q5B A;  3MPJ A;  3MDE A;  3X0Y A;  4DOY A;  2YYJ A;  4XVX A;  2C12 A;  5K3J A;  4KCF A;  2R0N A;  3L1T A;  4WJY A;  1R2J A;  3UU9 A;  3MDD A;  1W07 A;  3F29 A;  3D9E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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