3MDDA

Crystal structures of medium chain acyl-coa dehydrogenase from pig liver mitochondria with and without substrate
Total Genus 145
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
385
structure length
385
Chain Sequence
GFSFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESFGGLGLGIIDSCLITEELAYGCTGVQTAIEANTLGQVPLIIGGNYQQQKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPASKAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKIAMGTFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELARLSYQRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDAKIYQIYEGTAQIQRIIIAREHIGRYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords MEDIUM CHAIN ACYL-COA DEHYDROGENASE
publication title Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate.
pubmed doi rcsb
source organism Sus scrofa
molecule tags Oxidoreductase
total genus 145
structure length 385
sequence length 385
chains with identical sequence B
ec nomenclature ec 1.3.8.7: Medium-chain acyl-CoA dehydrogenase.
pdb deposition date 1994-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3mddA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3mddA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3mddA02
3X0YA 3RKHA 3EOMA 4G5EA 4HR3A 2EBAA 4Q5CA 3II9A 2FONA 3MPJA 4L3YA 2YYGA 2JIFA 4Q4UA 3SCEA 1RX0A 2YYIA 4XVXA 1EGDA 3TORA 1FS8A 2A1TA 2RF7A 1IS2A 3D9DA 3D9FA 3MXLA 3X0XA 4IV6A 3M9VA 4ZXVA 4P13A 4L38A 2RDZA 3MDEA 4JEKA 1FS9A 2C0UA 4X28C 3P4TA 3BNJA 3AFEA 3UU9A 2CX9A 1EGEA 1GU6A 1R2JA 1U8VA 3SF6A 1QDBA 2Z1QA 2PG0A 2OR0A 2J7AA 3LGQA 2OT4A 4ZYJA 1IVHA 2RFQA 2ZO5A 1W07A 4M9AA 4Q0TA 3MDDA 3L1TA 3GQTA 3OWMA 5K3JA 3S7WA 3NF4A 4W9UA 3BNFA 3EONA 3R7KA 2YYJA 2YYKA 4X28A 3PFDA 5K3IA 3MMOA 3D9GA 3OWAA 3SWOA 5K3GA 4KCFA 4L1FA 2IX6A 4DOYA 3F29A 3GM6A 3TTBA 1WS9A 2C12A 4KTOA 2VIGA 1BUCA 4L3XA 3FO3A 5K3HA 2E81A 3OIBA 4IRNA 1UDYA 3LG1A 4RM7A 3SXQA 2E80A 2IX5A 2REHA 2JBSA 3MKHA 1EGCA 2D29A 2YYMA 2UXWA 4Q1OA 2YYLA 4U83A 4N5FA 3BNGA 4L3ZA 2VR0A 3HWCA 1SIRA 3D1IA 3UBRA 2R0MA 3AFFA 4OO2A 1FS7A 2WBIA 3MPIA 1OAHA 3D9EA 3GNCA 4Q5BA 1T9GA 3D6BA 2DVLA 2JBRA 3B96A 4WJYA 1JQIA 2DDHA 2JBTA 4NXLA 4Q17A 1UKWA 2R0NA 2ZAFA 4O5MA 3FCJA 3BNHA 1SIQA
chains in the Genus database with same CATH superfamily
2E0AA 4E01A 2XS8A 4V26A 5EZ3A 3X0YA 4FF2A 3RKHA 3EOMA 4G5EA 3X29A 2ZKJA 2GBBA 4HR3A 2EBAA 4Q5CA 4DZYA 3II9A 1K8TA 4HKRA 2FONA 3MPJA 4L3YA 2YYGA 1GKZA 4FZ4A 1SC5A 2JIFA 4Q4UA 3SCEA 4H7QA 5J71A 1RX0A 2EBFX 2YYIA 1Y8PA 2HJNA 3DJLA 2ZDXA 4H85A 1Y0VA 2Q8HA 4XVXA 4MPEA 3TZ4A 4E00A 1EGDA 3TORA 1FS8A 2A1TA 2RF7A 2ZDYA 1IS2A 3D9DA 3CRLA 3D9FA 4MP2A 3Q23A 3MXLA 3X0XA 4IV6A 3M9VA 4ZXVA 4P13A 4H81A 4MPNA 4L38A 3Q22A 2RDZA 3MDEA 4KSFA 4JEKA 3CRKA 1FS9A 4FF3A 2QR4A 1X8ZA 5B5WA 1K93A 2VF1A 2C0UA 4X28C 1RP3A 5M4MA 5M4KA 3P4TA 5BRKA 1RJ1A 3BNJA 3AFEA 1JM6A 3TZ0A 2CX9A 3UU9A 1EGEA 1GU6A 1R2JA 1U8VA 2FP2A 3SF6A 1QDBA 4JIOA 3TZ5A 3Q24A 2Z1QA 2YGWA 2PG0A 2BU5A 3Q0AA 2OR0A 2J7AA 2XS1A 3LGQA 1LVCA 2OEXA 4F0XA 5B5VA 4FF4A 2OT4A 4ZYJA 1IVHA 2RFQA 2ZO5A 2AO2A 2AZEA 2LFWA 1W07A 4M9AA 4Q0TA 5B6BA 4FF1A 2EC5A 3MDDA 3VKGA 3L1TA 3GQTA 4MPCA 3C3LA 3VKHA 5J6AA 3OWMA 1PI1A 3N0RA 5K3JA 2CJ8A 3S7WA 2BU6A 3NF4A 1X90A 4W9UA 3BNFA 1Y8OA 3EONA 3R7KA 1R3BA 1XFWA 2YYKA 2YYJA 4JIZA 4X28A 2PNRA 3PFDA 1GKXA 5K3IA 3MMOA 3D9GA 3OWAA 1GJVA 3SWOA 2CJ5A 3D2RA 5K3GA 4KCFA 4L1FA 2IX6A 4DOYA 3F29A 3GM6A 2BTZA 1WS9A 2C12A 4KTOA 1XG2B 2VIGA 4KS9A 1BUCA 4L3XA 3FO3A 5K3HA 1X91A 2E81A 3CE2A 3OIBA 4IRNA 1XFVA 2OJQA 1UDYA 3KMLA 4RM7A 1RJ4A 3LG1A 4LQQB 2Q8GA 3SXQA 2E80A 2Q8FA 2IX5A 2REHA 2JBSA 3MKHA 4MP7A 3U33A 3VADA 1EGCA 4LQSB 2R05A 2D29A 2YYMA 3C46A 1XFYA 2UXWA 4G97A 4Q1OA 2YYLA 2CJ7A 4U83A 2F6LA 2BU2A 4N5FA 2FP1A 1XFUA 4AI6A 3BNGA 2CJ6A 4J1VA 4L3ZA 2OEVA 2PO4A 1XFZA 2BU8A 2R02A 2VR0A 3HWCA 1SIRA 1K90A 3D1IA 4AKGA 2Q8IA 3UBRA 2XQRB 2BU7A 2R0MA 3AFFA 2CJ4A 4OO2A 1FS7A 2WBIA 5M4PA 5M4NA 3MPIA 1OAHA 3D9EA 3GNCA 4Q5BA 1T9GA 3TTBA 4E02A 4AKIA 3D6BA 3C2PA 4AKHA 2DVLA 2JBRA 1PK0A 1Y8NA 4QICA 3B96A 5BRMA 1XFXA 4P79A 4WJYA 1S26A 1JQIA 5GJWE 2DDHA 1SK6A 2JBTA 4NXLA 4Q17A 1UKWA 2R0NA 2R03A 4HKSA 4KSAA 5GJVE 4V25A 2ZAFA 4O5MA 3FCJA 3BNHA 2EBHX 1SIQA 3TZ2A
chains in the Genus database with same CATH topology
3X0YA 3RKHA 3EOMA 4G5EA 4HR3A 2EBAA 4Q5CA 3II9A 2FONA 3MPJA 4L3YA 2YYGA 2JIFA 4Q4UA 3SCEA 1RX0A 2YYIA 4XVXA 1EGDA 3TORA 1FS8A 2A1TA 2RF7A 1IS2A 3D9DA 3D9FA 3MXLA 3X0XA 4IV6A 3M9VA 4ZXVA 4P13A 4L38A 2RDZA 3MDEA 4JEKA 1FS9A 2C0UA 4X28C 3P4TA 3BNJA 3AFEA 3UU9A 2CX9A 1EGEA 1GU6A 1R2JA 1U8VA 3SF6A 1QDBA 2Z1QA 2PG0A 2OR0A 2J7AA 3LGQA 2OT4A 4ZYJA 1IVHA 2RFQA 2ZO5A 1W07A 4M9AA 4Q0TA 3MDDA 3L1TA 3GQTA 3OWMA 5K3JA 3S7WA 3NF4A 4W9UA 3BNFA 3EONA 3R7KA 2YYJA 2YYKA 4X28A 3PFDA 5K3IA 3MMOA 3D9GA 3OWAA 3SWOA 5K3GA 4KCFA 4L1FA 2IX6A 4DOYA 3F29A 3GM6A 3TTBA 1WS9A 2C12A 4KTOA 2VIGA 1BUCA 4L3XA 3FO3A 5K3HA 2E81A 3OIBA 4IRNA 1UDYA 3LG1A 4RM7A 3SXQA 2E80A 2IX5A 2REHA 2JBSA 3MKHA 1EGCA 2D29A 2YYMA 2UXWA 4Q1OA 2YYLA 4U83A 4N5FA 3BNGA 4L3ZA 2VR0A 3HWCA 1SIRA 3D1IA 3UBRA 2R0MA 3AFFA 4OO2A 1FS7A 2WBIA 3MPIA 1OAHA 3D9EA 3GNCA 4Q5BA 1T9GA 3D6BA 2DVLA 2JBRA 3B96A 4WJYA 1JQIA 2DDHA 2JBTA 4NXLA 4Q17A 1UKWA 2R0NA 2ZAFA 4O5MA 3FCJA 3BNHA 1SIQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3X0Y A;  3RKH A;  3EOM A;  4G5E A;  4HR3 A;  2EBA A;  4Q5C A;  3II9 A;  2FON A;  3MPJ A;  4L3Y A;  2YYG A;  2JIF A;  4Q4U A;  3SCE A;  1RX0 A;  2YYI A;  4XVX A;  1EGD A;  3TOR A;  1FS8 A;  2A1T A;  2RF7 A;  1IS2 A;  3D9D A;  3D9F A;  3MXL A;  3X0X A;  4IV6 A;  3M9V A;  4ZXV A;  4P13 A;  4L38 A;  2RDZ A;  3MDE A;  4JEK A;  1FS9 A;  2C0U A;  4X28 C;  3P4T A;  3BNJ A;  3AFE A;  3UU9 A;  2CX9 A;  1EGE A;  1GU6 A;  1R2J A;  1U8V A;  3SF6 A;  1QDB A;  2Z1Q A;  2PG0 A;  2OR0 A;  2J7A A;  3LGQ A;  2OT4 A;  4ZYJ A;  1IVH A;  2RFQ A;  2ZO5 A;  1W07 A;  4M9A A;  4Q0T A;  3MDD A;  3L1T A;  3GQT A;  3OWM A;  5K3J A;  3S7W A;  3NF4 A;  4W9U A;  3BNF A;  3EON A;  3R7K A;  2YYJ A;  2YYK A;  4X28 A;  3PFD A;  5K3I A;  3MMO A;  3D9G A;  3OWA A;  3SWO A;  5K3G A;  4KCF A;  4L1F A;  2IX6 A;  4DOY A;  3F29 A;  3GM6 A;  3TTB A;  1WS9 A;  2C12 A;  4KTO A;  2VIG A;  1BUC A;  4L3X A;  3FO3 A;  5K3H A;  2E81 A;  3OIB A;  4IRN A;  1UDY A;  3LG1 A;  4RM7 A;  3SXQ A;  2E80 A;  2IX5 A;  2REH A;  2JBS A;  3MKH A;  1EGC A;  2D29 A;  2YYM A;  2UXW A;  4Q1O A;  2YYL A;  4U83 A;  4N5F A;  3BNG A;  4L3Z A;  2VR0 A;  3HWC A;  1SIR A;  3D1I A;  3UBR A;  2R0M A;  3AFF A;  4OO2 A;  1FS7 A;  2WBI A;  3MPI A;  1OAH A;  3D9E A;  3GNC A;  4Q5B A;  1T9G A;  3D6B A;  2DVL A;  2JBR A;  3B96 A;  4WJY A;  1JQI A;  2DDH A;  2JBT A;  4NXL A;  4Q17 A;  1UKW A;  2R0N A;  2ZAF A;  4O5M A;  3FCJ A;  3BNH A;  1SIQ A; 
#chains in the Genus database with same CATH topology
 2E0A A;  4E01 A;  2XS8 A;  4V26 A;  5EZ3 A;  3X0Y A;  4FF2 A;  3RKH A;  3EOM A;  4G5E A;  3X29 A;  2ZKJ A;  2GBB A;  4HR3 A;  2EBA A;  4Q5C A;  4DZY A;  3II9 A;  1K8T A;  4HKR A;  2FON A;  3MPJ A;  4L3Y A;  2YYG A;  1GKZ A;  4FZ4 A;  1SC5 A;  2JIF A;  4Q4U A;  3SCE A;  4H7Q A;  5J71 A;  1RX0 A;  2EBF X;  2YYI A;  1Y8P A;  2HJN A;  3DJL A;  2ZDX A;  4H85 A;  1Y0V A;  2Q8H A;  4XVX A;  4MPE A;  3TZ4 A;  4E00 A;  1EGD A;  3TOR A;  1FS8 A;  2A1T A;  2RF7 A;  2ZDY A;  1IS2 A;  3D9D A;  3CRL A;  3D9F A;  4MP2 A;  3Q23 A;  3MXL A;  3X0X A;  4IV6 A;  3M9V A;  4ZXV A;  4P13 A;  4H81 A;  4MPN A;  4L38 A;  3Q22 A;  2RDZ A;  3MDE A;  4KSF A;  4JEK A;  3CRK A;  1FS9 A;  4FF3 A;  2QR4 A;  1X8Z A;  5B5W A;  1K93 A;  2VF1 A;  2C0U A;  4X28 C;  1RP3 A;  5M4M A;  5M4K A;  3P4T A;  5BRK A;  1RJ1 A;  3BNJ A;  3AFE A;  1JM6 A;  3TZ0 A;  2CX9 A;  3UU9 A;  1EGE A;  1GU6 A;  1R2J A;  1U8V A;  2FP2 A;  3SF6 A;  1QDB A;  4JIO A;  3TZ5 A;  3Q24 A;  2Z1Q A;  2YGW A;  2PG0 A;  2BU5 A;  3Q0A A;  2OR0 A;  2J7A A;  2XS1 A;  3LGQ A;  1LVC A;  2OEX A;  4F0X A;  5B5V A;  4FF4 A;  2OT4 A;  4ZYJ A;  1IVH A;  2RFQ A;  2ZO5 A;  2AO2 A;  2AZE A;  2LFW A;  1W07 A;  4M9A A;  4Q0T A;  5B6B A;  4FF1 A;  2EC5 A;  3MDD A;  3VKG A;  3L1T A;  3GQT A;  4MPC A;  3C3L A;  3VKH A;  5J6A A;  3OWM A;  1PI1 A;  3N0R A;  5K3J A;  2CJ8 A;  3S7W A;  2BU6 A;  3NF4 A;  1X90 A;  4W9U A;  3BNF A;  1Y8O A;  3EON A;  3R7K A;  1R3B A;  1XFW A;  2YYK A;  2YYJ A;  4JIZ A;  4X28 A;  2PNR A;  3PFD A;  1GKX A;  5K3I A;  3MMO A;  3D9G A;  3OWA A;  1GJV A;  3SWO A;  2CJ5 A;  3D2R A;  5K3G A;  4KCF A;  4L1F A;  2IX6 A;  4DOY A;  3F29 A;  3GM6 A;  2BTZ A;  1WS9 A;  2C12 A;  4KTO A;  1XG2 B;  2VIG A;  4KS9 A;  1BUC A;  4L3X A;  3FO3 A;  5K3H A;  1X91 A;  2E81 A;  3CE2 A;  3OIB A;  4IRN A;  1XFV A;  2OJQ A;  1UDY A;  3KML A;  4RM7 A;  1RJ4 A;  3LG1 A;  4LQQ B;  2Q8G A;  3SXQ A;  2E80 A;  2Q8F A;  2IX5 A;  2REH A;  2JBS A;  3MKH A;  4MP7 A;  3U33 A;  3VAD A;  1EGC A;  4LQS B;  2R05 A;  2D29 A;  2YYM A;  3C46 A;  1XFY A;  2UXW A;  4G97 A;  4Q1O A;  2YYL A;  2CJ7 A;  4U83 A;  2F6L A;  2BU2 A;  4N5F A;  2FP1 A;  1XFU A;  4AI6 A;  3BNG A;  2CJ6 A;  4J1V A;  4L3Z A;  2OEV A;  2PO4 A;  1XFZ A;  2BU8 A;  2R02 A;  2VR0 A;  3HWC A;  1SIR A;  1K90 A;  3D1I A;  4AKG A;  2Q8I A;  3UBR A;  2XQR B;  2BU7 A;  2R0M A;  3AFF A;  2CJ4 A;  4OO2 A;  1FS7 A;  2WBI A;  5M4P A;  5M4N A;  3MPI A;  1OAH A;  3D9E A;  3GNC A;  4Q5B A;  1T9G A;  3TTB A;  4E02 A;  4AKI A;  3D6B A;  3C2P A;  4AKH A;  2DVL A;  2JBR A;  1PK0 A;  1Y8N A;  4QIC A;  3B96 A;  5BRM A;  1XFX A;  4P79 A;  4WJY A;  1S26 A;  1JQI A;  5GJW E;  2DDH A;  1SK6 A;  2JBT A;  4NXL A;  4Q17 A;  1UKW A;  2R0N A;  2R03 A;  4HKS A;  4KSA A;  5GJV E;  4V25 A;  2ZAF A;  4O5M A;  3FCJ A;  3BNH A;  2EBH X;  1SIQ A;  3TZ2 A; 
#chains in the Genus database with same CATH homology
 3X0Y A;  3RKH A;  3EOM A;  4G5E A;  4HR3 A;  2EBA A;  4Q5C A;  3II9 A;  2FON A;  3MPJ A;  4L3Y A;  2YYG A;  2JIF A;  4Q4U A;  3SCE A;  1RX0 A;  2YYI A;  4XVX A;  1EGD A;  3TOR A;  1FS8 A;  2A1T A;  2RF7 A;  1IS2 A;  3D9D A;  3D9F A;  3MXL A;  3X0X A;  4IV6 A;  3M9V A;  4ZXV A;  4P13 A;  4L38 A;  2RDZ A;  3MDE A;  4JEK A;  1FS9 A;  2C0U A;  4X28 C;  3P4T A;  3BNJ A;  3AFE A;  3UU9 A;  2CX9 A;  1EGE A;  1GU6 A;  1R2J A;  1U8V A;  3SF6 A;  1QDB A;  2Z1Q A;  2PG0 A;  2OR0 A;  2J7A A;  3LGQ A;  2OT4 A;  4ZYJ A;  1IVH A;  2RFQ A;  2ZO5 A;  1W07 A;  4M9A A;  4Q0T A;  3MDD A;  3L1T A;  3GQT A;  3OWM A;  5K3J A;  3S7W A;  3NF4 A;  4W9U A;  3BNF A;  3EON A;  3R7K A;  2YYJ A;  2YYK A;  4X28 A;  3PFD A;  5K3I A;  3MMO A;  3D9G A;  3OWA A;  3SWO A;  5K3G A;  4KCF A;  4L1F A;  2IX6 A;  4DOY A;  3F29 A;  3GM6 A;  3TTB A;  1WS9 A;  2C12 A;  4KTO A;  2VIG A;  1BUC A;  4L3X A;  3FO3 A;  5K3H A;  2E81 A;  3OIB A;  4IRN A;  1UDY A;  3LG1 A;  4RM7 A;  3SXQ A;  2E80 A;  2IX5 A;  2REH A;  2JBS A;  3MKH A;  1EGC A;  2D29 A;  2YYM A;  2UXW A;  4Q1O A;  2YYL A;  4U83 A;  4N5F A;  3BNG A;  4L3Z A;  2VR0 A;  3HWC A;  1SIR A;  3D1I A;  3UBR A;  2R0M A;  3AFF A;  4OO2 A;  1FS7 A;  2WBI A;  3MPI A;  1OAH A;  3D9E A;  3GNC A;  4Q5B A;  1T9G A;  3D6B A;  2DVL A;  2JBR A;  3B96 A;  4WJY A;  1JQI A;  2DDH A;  2JBT A;  4NXL A;  4Q17 A;  1UKW A;  2R0N A;  2ZAF A;  4O5M A;  3FCJ A;  3BNH A;  1SIQ A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...