3MDDA

Crystal structures of medium chain acyl-coa dehydrogenase from pig liver mitochondria with and without substrate
Total Genus 145
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
145
sequence length
385
structure length
385
Chain Sequence
GFSFELTEQQKEFQATARKFAREEIIPVAAEYDRTGEYPVPLLKRAWELGLMNTHIPESFGGLGLGIIDSCLITEELAYGCTGVQTAIEANTLGQVPLIIGGNYQQQKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKGDEYIINGQKMWITNGGKANWYFLLARSDPDPKAPASKAFTGFIVEADTPGVQIGRKEINMGQRCSDTRGIVFEDVRVPKENVLTGEGAGFKIAMGTFDKTRPPVAAGAVGLAQRALDEATKYALERKTFGKLLAEHQGISFLLADMAMKVELARLSYQRAAWEIDSGRRNTYYASIAKAYAADIANQLATDAVQVFGGNGFNTEYPVEKLMRDAKIYQIYEGTAQIQRIIIAREHIGRYK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords MEDIUM CHAIN ACYL-COA DEHYDROGENASE
publication title Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate.
pubmed doi rcsb
source organism Sus scrofa
total genus 145
structure length 385
sequence length 385
chains with identical sequence B
ec nomenclature ec 1.3.8.7: Medium-chain acyl-CoA dehydrogenase.
pdb deposition date 1994-07-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
A PF02770 Acyl-CoA_dh_M Acyl-CoA dehydrogenase, middle domain
A PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 3mddA01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 3mddA03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 3mddA02
2OT4A 2REHA 3SF6A 1W07A 3D9EA 4IRNA 5K3GA 3MXLA 4Q17A 3HWCA 4DOYA 1U8VA 4Q1OA 4RM7A 5K3HA 4IV6A 2PG0A 4L38A 2RFQA 2D29A 3B96A 2YYKA 3D9FA 2JBSA 4W9UA 4ZXVA 4L3YA 5K3JA 2DDHA 2JBRA 3GM6A 3GNCA 2E81A 1IVHA 2A1TA 1WS9A 3F29A 5K3IA 4L3XA 3II9A 3SWOA 1SIRA 2C12A 3MPJA 3NF4A 1FS8A 3FO3A 3P4TA 1FS7A 1T9GA 4KCFA 2FONA 3BNJA 4O5MA 2UXWA 3L1TA 3MDEA 3D1IA 3UU9A 1EGCA 2CX9A 4X28A 4XVXA 3RKHA 2RF7A 3OWAA 3S7WA 2YYLA 4Q5CA 4L3ZA 3EONA 3MKHA 3GQTA 3BNHA 3TORA 2IX6A 3D9GA 3MPIA 3MMOA 3OWMA 2Z1QA 4HR3A 1OAHA 4L1FA 1GU6A 2ZAFA 3FCJA 2YYJA 3MDDA 2RDZA 2J7AA 3D9DA 3R7KA 4NXLA 2YYMA 4N5FA 1R2JA 1UKWA 3EOMA 4ZYJA 4X28C 3AFFA 3TTBA 3LGQA 4U83A 1EGDA 2IX5A 2OR0A 3SCEA 3M9VA 1JQIA 2YYGA 3X0XA 1BUCA 3BNFA 4M9AA 4Q0TA 4OO2A 2ZO5A 4P13A 2JIFA 3OIBA 1RX0A 4Q5BA 2VR0A 3UBRA 4Q4UA 3PFDA 2WBIA 4G5EA 1EGEA 2EBAA 1QDBA 2C0UA 2YYIA 3D6BA 2VIGA 1UDYA 3BNGA 2R0MA 2DVLA 4WJYA 3SXQA 4JEKA 1IS2A 2E80A 3AFEA 2R0NA 3LG1A 1FS9A 2JBTA 4KTOA 3X0YA 1SIQA
chains in the Genus database with same CATH superfamily
2CJ4A 2OT4A 2REHA 3SF6A 2CJ5A 1W07A 3D2RA 3D9EA 4IRNA 5K3GA 4HKSA 3MXLA 1Y8NA 2R03A 2YGWA 4Q17A 2GBBA 3HWCA 4DOYA 1K8TA 1U8VA 1XFYA 4G97A 3TZ0A 3Q22A 4FF4A 4KSFA 4Q1OA 3CE2A 4RM7A 5K3HA 1XFVA 1Y8OA 5J6AA 2BU8A 4H81A 4IV6A 2PG0A 4E02A 4L38A 2RFQA 2PO4A 2D29A 3B96A 2FP2A 2ZDYA 2YYKA 3C3LA 3D9FA 2JBSA 2QR4A 4W9UA 4ZXVA 4L3YA 4H85A 4FF1A 4AKGA 5K3JA 2DDHA 2JBRA 3GM6A 2Q8GA 4H7QA 3GNCA 2E81A 2R02A 5EZ3A 1IVHA 2Q8IA 2A1TA 1WS9A 1XFXA 4J1VA 1PI1A 3F29A 3Q0AA 5K3IA 2BU6A 4L3XA 5B5VA 3II9A 3SWOA 1SIRA 2AZEA 4QICA 2C12A 3MPJA 3NF4A 1FS8A 2ZKJA 2XS1A 3FO3A 4E00A 2OEVA 4AKHA 3P4TA 1FS7A 1T9GA 4KCFA 1Y0VA 4P79A 4V26A 4E01A 3C46A 2FONA 3BNJA 2BU2A 4O5MA 4AKIA 1GKZA 2UXWA 4FZ4A 3L1TA 3MDEA 4JIZA 3D1IA 3VADA 1R3BA 2CJ8A 5B6BA 4LQQB 2FP1A 3UU9A 1EGCA 2CX9A 4X28A 3DJLA 4XVXA 2XQRB 3RKHA 4MPEA 2RF7A 3OWAA 5BRMA 3S7WA 2YYLA 4HKRA 4Q5CA 4L3ZA 3EONA 3MKHA 3GQTA 2XS8A 3BNHA 3TORA 2IX6A 3D9GA 3MPIA 3MMOA 3OWMA 5B5WA 1K90A 4DZYA 2Z1QA 4HR3A 1OAHA 1S26A 4L1FA 1XFWA 2AO2A 2ZDXA 3VKHA 3U33A 3VKGA 1RJ1A 1XFZA 2EC5A 1GU6A 1GJVA 2ZAFA 3FCJA 2OEXA 2YYJA 5M4NA 1K93A 1SK6A 3MDDA 2RDZA 3N0RA 4MPNA 2HJNA 2J7AA 3D9DA 3R7KA 3TZ5A 4NXLA 2F6LA 4N5FA 2LFWA 2YYMA 4KSAA 1R2JA 1X90A 2EBFX 4MPCA 5BRKA 3X29A 1JM6A 5M4PA 1UKWA 1LVCA 4MP7A 2CJ6A 2Q8FA 4FF2A 3EOMA 4ZYJA 4X28C 3AFFA 2BTZA 2BU7A 2R05A 2BU5A 1Y8PA 3LGQA 4U83A 1EGDA 3TTBA 3Q24A 4FF3A 2IX5A 2OR0A 3KMLA 4LQSB 1XG2B 3SCEA 1PK0A 3M9VA 5M4KA 1JQIA 2VF1A 4KS9A 5J71A 2PNRA 2YYGA 3X0XA 2EBHX 2Q8HA 1BUCA 1X91A 3BNFA 4M9AA 4Q0TA 4OO2A 1SC5A 2ZO5A 5GJWE 4P13A 3TZ4A 2JIFA 3OIBA 1RX0A 1XFUA 3CRLA 3Q23A 4Q5BA 1RJ4A 3C2PA 2VR0A 3UBRA 2E0AA 4Q4UA 3PFDA 4JIOA 4V25A 2WBIA 1RP3A 4G5EA 5GJVE 1EGEA 3CRKA 2EBAA 1QDBA 2C0UA 2YYIA 3D6BA 2CJ7A 2OJQA 4MP2A 4F0XA 2VIGA 1X8ZA 1UDYA 1GKXA 3TZ2A 3BNGA 2R0MA 2DVLA 4WJYA 3SXQA 5M4MA 4JEKA 1IS2A 2E80A 3AFEA 2R0NA 3LG1A 1FS9A 2JBTA 4KTOA 3X0YA 4AI6A 1SIQA
chains in the Genus database with same CATH topology
2OT4A 2REHA 3SF6A 1W07A 3D9EA 4IRNA 5K3GA 3MXLA 4Q17A 3HWCA 4DOYA 1U8VA 4Q1OA 4RM7A 5K3HA 4IV6A 2PG0A 4L38A 2RFQA 2D29A 3B96A 2YYKA 3D9FA 2JBSA 4W9UA 4ZXVA 4L3YA 5K3JA 2DDHA 2JBRA 3GM6A 3GNCA 2E81A 1IVHA 2A1TA 1WS9A 3F29A 5K3IA 4L3XA 3II9A 3SWOA 1SIRA 2C12A 3MPJA 3NF4A 1FS8A 3FO3A 3P4TA 1FS7A 1T9GA 4KCFA 2FONA 3BNJA 4O5MA 2UXWA 3L1TA 3MDEA 3D1IA 3UU9A 1EGCA 2CX9A 4X28A 4XVXA 3RKHA 2RF7A 3OWAA 3S7WA 2YYLA 4Q5CA 4L3ZA 3EONA 3MKHA 3GQTA 3BNHA 3TORA 2IX6A 3D9GA 3MPIA 3MMOA 3OWMA 2Z1QA 4HR3A 1OAHA 4L1FA 1GU6A 2ZAFA 3FCJA 2YYJA 3MDDA 2RDZA 2J7AA 3D9DA 3R7KA 4NXLA 2YYMA 4N5FA 1R2JA 1UKWA 3EOMA 4ZYJA 4X28C 3AFFA 3TTBA 3LGQA 4U83A 1EGDA 2IX5A 2OR0A 3SCEA 3M9VA 1JQIA 2YYGA 3X0XA 1BUCA 3BNFA 4M9AA 4Q0TA 4OO2A 2ZO5A 4P13A 2JIFA 3OIBA 1RX0A 4Q5BA 2VR0A 3UBRA 4Q4UA 3PFDA 2WBIA 4G5EA 1EGEA 2EBAA 1QDBA 2C0UA 2YYIA 3D6BA 2VIGA 1UDYA 3BNGA 2R0MA 2DVLA 4WJYA 3SXQA 4JEKA 1IS2A 2E80A 3AFEA 2R0NA 3LG1A 1FS9A 2JBTA 4KTOA 3X0YA 1SIQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2OT4 A;  2REH A;  3SF6 A;  1W07 A;  3D9E A;  4IRN A;  5K3G A;  3MXL A;  4Q17 A;  3HWC A;  4DOY A;  1U8V A;  4Q1O A;  4RM7 A;  5K3H A;  4IV6 A;  2PG0 A;  4L38 A;  2RFQ A;  2D29 A;  3B96 A;  2YYK A;  3D9F A;  2JBS A;  4W9U A;  4ZXV A;  4L3Y A;  5K3J A;  2DDH A;  2JBR A;  3GM6 A;  3GNC A;  2E81 A;  1IVH A;  2A1T A;  1WS9 A;  3F29 A;  5K3I A;  4L3X A;  3II9 A;  3SWO A;  1SIR A;  2C12 A;  3MPJ A;  3NF4 A;  1FS8 A;  3FO3 A;  3P4T A;  1FS7 A;  1T9G A;  4KCF A;  2FON A;  3BNJ A;  4O5M A;  2UXW A;  3L1T A;  3MDE A;  3D1I A;  3UU9 A;  1EGC A;  2CX9 A;  4X28 A;  4XVX A;  3RKH A;  2RF7 A;  3OWA A;  3S7W A;  2YYL A;  4Q5C A;  4L3Z A;  3EON A;  3MKH A;  3GQT A;  3BNH A;  3TOR A;  2IX6 A;  3D9G A;  3MPI A;  3MMO A;  3OWM A;  2Z1Q A;  4HR3 A;  1OAH A;  4L1F A;  1GU6 A;  2ZAF A;  3FCJ A;  2YYJ A;  3MDD A;  2RDZ A;  2J7A A;  3D9D A;  3R7K A;  4NXL A;  2YYM A;  4N5F A;  1R2J A;  1UKW A;  3EOM A;  4ZYJ A;  4X28 C;  3AFF A;  3TTB A;  3LGQ A;  4U83 A;  1EGD A;  2IX5 A;  2OR0 A;  3SCE A;  3M9V A;  1JQI A;  2YYG A;  3X0X A;  1BUC A;  3BNF A;  4M9A A;  4Q0T A;  4OO2 A;  2ZO5 A;  4P13 A;  2JIF A;  3OIB A;  1RX0 A;  4Q5B A;  2VR0 A;  3UBR A;  4Q4U A;  3PFD A;  2WBI A;  4G5E A;  1EGE A;  2EBA A;  1QDB A;  2C0U A;  2YYI A;  3D6B A;  2VIG A;  1UDY A;  3BNG A;  2R0M A;  2DVL A;  4WJY A;  3SXQ A;  4JEK A;  1IS2 A;  2E80 A;  3AFE A;  2R0N A;  3LG1 A;  1FS9 A;  2JBT A;  4KTO A;  3X0Y A;  1SIQ A; 
#chains in the Genus database with same CATH topology
 2CJ4 A;  2OT4 A;  2REH A;  3SF6 A;  2CJ5 A;  1W07 A;  3D2R A;  3D9E A;  4IRN A;  5K3G A;  4HKS A;  3MXL A;  1Y8N A;  2R03 A;  2YGW A;  4Q17 A;  2GBB A;  3HWC A;  4DOY A;  1K8T A;  1U8V A;  1XFY A;  4G97 A;  3TZ0 A;  3Q22 A;  4FF4 A;  4KSF A;  4Q1O A;  3CE2 A;  4RM7 A;  5K3H A;  1XFV A;  1Y8O A;  5J6A A;  2BU8 A;  4H81 A;  4IV6 A;  2PG0 A;  4E02 A;  4L38 A;  2RFQ A;  2PO4 A;  2D29 A;  3B96 A;  2FP2 A;  2ZDY A;  2YYK A;  3C3L A;  3D9F A;  2JBS A;  2QR4 A;  4W9U A;  4ZXV A;  4L3Y A;  4H85 A;  4FF1 A;  4AKG A;  5K3J A;  2DDH A;  2JBR A;  3GM6 A;  2Q8G A;  4H7Q A;  3GNC A;  2E81 A;  2R02 A;  5EZ3 A;  1IVH A;  2Q8I A;  2A1T A;  1WS9 A;  1XFX A;  4J1V A;  1PI1 A;  3F29 A;  3Q0A A;  5K3I A;  2BU6 A;  4L3X A;  5B5V A;  3II9 A;  3SWO A;  1SIR A;  2AZE A;  4QIC A;  2C12 A;  3MPJ A;  3NF4 A;  1FS8 A;  2ZKJ A;  2XS1 A;  3FO3 A;  4E00 A;  2OEV A;  4AKH A;  3P4T A;  1FS7 A;  1T9G A;  4KCF A;  1Y0V A;  4P79 A;  4V26 A;  4E01 A;  3C46 A;  2FON A;  3BNJ A;  2BU2 A;  4O5M A;  4AKI A;  1GKZ A;  2UXW A;  4FZ4 A;  3L1T A;  3MDE A;  4JIZ A;  3D1I A;  3VAD A;  1R3B A;  2CJ8 A;  5B6B A;  4LQQ B;  2FP1 A;  3UU9 A;  1EGC A;  2CX9 A;  4X28 A;  3DJL A;  4XVX A;  2XQR B;  3RKH A;  4MPE A;  2RF7 A;  3OWA A;  5BRM A;  3S7W A;  2YYL A;  4HKR A;  4Q5C A;  4L3Z A;  3EON A;  3MKH A;  3GQT A;  2XS8 A;  3BNH A;  3TOR A;  2IX6 A;  3D9G A;  3MPI A;  3MMO A;  3OWM A;  5B5W A;  1K90 A;  4DZY A;  2Z1Q A;  4HR3 A;  1OAH A;  1S26 A;  4L1F A;  1XFW A;  2AO2 A;  2ZDX A;  3VKH A;  3U33 A;  3VKG A;  1RJ1 A;  1XFZ A;  2EC5 A;  1GU6 A;  1GJV A;  2ZAF A;  3FCJ A;  2OEX A;  2YYJ A;  5M4N A;  1K93 A;  1SK6 A;  3MDD A;  2RDZ A;  3N0R A;  4MPN A;  2HJN A;  2J7A A;  3D9D A;  3R7K A;  3TZ5 A;  4NXL A;  2F6L A;  4N5F A;  2LFW A;  2YYM A;  4KSA A;  1R2J A;  1X90 A;  2EBF X;  4MPC A;  5BRK A;  3X29 A;  1JM6 A;  5M4P A;  1UKW A;  1LVC A;  4MP7 A;  2CJ6 A;  2Q8F A;  4FF2 A;  3EOM A;  4ZYJ A;  4X28 C;  3AFF A;  2BTZ A;  2BU7 A;  2R05 A;  2BU5 A;  1Y8P A;  3LGQ A;  4U83 A;  1EGD A;  3TTB A;  3Q24 A;  4FF3 A;  2IX5 A;  2OR0 A;  3KML A;  4LQS B;  1XG2 B;  3SCE A;  1PK0 A;  3M9V A;  5M4K A;  1JQI A;  2VF1 A;  4KS9 A;  5J71 A;  2PNR A;  2YYG A;  3X0X A;  2EBH X;  2Q8H A;  1BUC A;  1X91 A;  3BNF A;  4M9A A;  4Q0T A;  4OO2 A;  1SC5 A;  2ZO5 A;  5GJW E;  4P13 A;  3TZ4 A;  2JIF A;  3OIB A;  1RX0 A;  1XFU A;  3CRL A;  3Q23 A;  4Q5B A;  1RJ4 A;  3C2P A;  2VR0 A;  3UBR A;  2E0A A;  4Q4U A;  3PFD A;  4JIO A;  4V25 A;  2WBI A;  1RP3 A;  4G5E A;  5GJV E;  1EGE A;  3CRK A;  2EBA A;  1QDB A;  2C0U A;  2YYI A;  3D6B A;  2CJ7 A;  2OJQ A;  4MP2 A;  4F0X A;  2VIG A;  1X8Z A;  1UDY A;  1GKX A;  3TZ2 A;  3BNG A;  2R0M A;  2DVL A;  4WJY A;  3SXQ A;  5M4M A;  4JEK A;  1IS2 A;  2E80 A;  3AFE A;  2R0N A;  3LG1 A;  1FS9 A;  2JBT A;  4KTO A;  3X0Y A;  4AI6 A;  1SIQ A; 
#chains in the Genus database with same CATH homology
 2OT4 A;  2REH A;  3SF6 A;  1W07 A;  3D9E A;  4IRN A;  5K3G A;  3MXL A;  4Q17 A;  3HWC A;  4DOY A;  1U8V A;  4Q1O A;  4RM7 A;  5K3H A;  4IV6 A;  2PG0 A;  4L38 A;  2RFQ A;  2D29 A;  3B96 A;  2YYK A;  3D9F A;  2JBS A;  4W9U A;  4ZXV A;  4L3Y A;  5K3J A;  2DDH A;  2JBR A;  3GM6 A;  3GNC A;  2E81 A;  1IVH A;  2A1T A;  1WS9 A;  3F29 A;  5K3I A;  4L3X A;  3II9 A;  3SWO A;  1SIR A;  2C12 A;  3MPJ A;  3NF4 A;  1FS8 A;  3FO3 A;  3P4T A;  1FS7 A;  1T9G A;  4KCF A;  2FON A;  3BNJ A;  4O5M A;  2UXW A;  3L1T A;  3MDE A;  3D1I A;  3UU9 A;  1EGC A;  2CX9 A;  4X28 A;  4XVX A;  3RKH A;  2RF7 A;  3OWA A;  3S7W A;  2YYL A;  4Q5C A;  4L3Z A;  3EON A;  3MKH A;  3GQT A;  3BNH A;  3TOR A;  2IX6 A;  3D9G A;  3MPI A;  3MMO A;  3OWM A;  2Z1Q A;  4HR3 A;  1OAH A;  4L1F A;  1GU6 A;  2ZAF A;  3FCJ A;  2YYJ A;  3MDD A;  2RDZ A;  2J7A A;  3D9D A;  3R7K A;  4NXL A;  2YYM A;  4N5F A;  1R2J A;  1UKW A;  3EOM A;  4ZYJ A;  4X28 C;  3AFF A;  3TTB A;  3LGQ A;  4U83 A;  1EGD A;  2IX5 A;  2OR0 A;  3SCE A;  3M9V A;  1JQI A;  2YYG A;  3X0X A;  1BUC A;  3BNF A;  4M9A A;  4Q0T A;  4OO2 A;  2ZO5 A;  4P13 A;  2JIF A;  3OIB A;  1RX0 A;  4Q5B A;  2VR0 A;  3UBR A;  4Q4U A;  3PFD A;  2WBI A;  4G5E A;  1EGE A;  2EBA A;  1QDB A;  2C0U A;  2YYI A;  3D6B A;  2VIG A;  1UDY A;  3BNG A;  2R0M A;  2DVL A;  4WJY A;  3SXQ A;  4JEK A;  1IS2 A;  2E80 A;  3AFE A;  2R0N A;  3LG1 A;  1FS9 A;  2JBT A;  4KTO A;  3X0Y A;  1SIQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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