1PK0 | Genus

Total Genus 152

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	152
sequence length	507
structure length	484
Chain Sequence	RIDVLKGEKALKASGLVPEHADAFKKIARELNTYILFRPVNKLATNLIKSGVATKGLNVHGKSSDWGPVAGYIPFDQDLSKKHGQQLAVEKGNLENKKSITEHEGEIGKIPLKLDHLRIEELKENGIILKGKKEIDNGKKYYLLESNNQVYEFRISDENNEVQYKTKEGKITVLGEKFNWRNIEVMAKNVEGVLKPLTADYDLFALAPSLTEIKKQIPQKEWDKVVNTPNSLEKQKGVTNLLIKYGIERKPDSTKGTLSNWQKQMLDRLNEAVKYTGYTGGDVVNHGTEQDNEEFPEKDNEIFIINPEGEFILTKNWEMTGRFIEKNITGKDYLYYFNRSYNKIAPGNKAYIEWTDPITKAKINTIPTSAEFIKNLSSIRRSSVKKIAGYLSDYYNSANHIFSQEKKRKISIFRGIQAYNEIENVLKSKQIAPEYKNYFQYLKERITNQVQLLLTHQKFKLLYKQLNFTENETDNFEVFQKIID

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 484 atoms

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484 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Lyase/metal binding protein
source organism	Bacillus anthracis
publication title	Selective inhibition of anthrax edema factor by adefovir, a drug for chronic hepatitis B virus infection. pubmed doi rcsb
molecule keywords	Calmodulin-sensitive adenylate cyclase
total genus	152
structure length	484
sequence length	507
chains with identical sequence	B, C
ec nomenclature	ec 4.6.1.1: Adenylate cyclase.
pdb deposition date	2003-06-04

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF03497	Anthrax_toxA	Anthrax toxin LF subunit

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.140.60	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A; domain 3	Butyryl-CoA Dehydrogenase, subunit A; domain 3	1pk0A03
3.90.1760.10	Alpha Beta	Alpha-Beta Complex	Adenylylcyclase toxin fold	Anthrax toxin, edema factor, central domain	1pk0A02

1S26A 1SK6A 1XFYA 1K8TA 1XFVA 1XFWA 1LVCA 1Y0VA 1XFZA 1YRTA 1ZOTA 1PK0A 1K93A 1XFUA 2COLA 1K90A 1XFXA 1YRUA
chains in the Genus database with same CATH superfamily

2CJ7A 4FF2A 3R7KA 4AKGA 2YGWA 2YYJA 2ZAFA 4KSFA 1Y8PA 4J1VA 4Q1OA 5K3JA 3SWOA 2CX9A 4H85A 4L3YA 3MXLA 4OO2A 4H81A 2Q8FA 5BRKA 2VR0A 2OJQA 3VKGA 1SIQA 1JQIA 2OEXA 1K93A 2OEVA 3BNJA 5K3GA 2XQRB 1UDYA 5B6BA 3Q23A 2AZEA 5GJWE 2EBFX 2CJ5A 4HKSA 3RKHA 4ZXVA 1W07A 3CE2A 2ZDYA 3C46A 2Q8GA 3MKHA 2C0UA 1RJ4A 2UXWA 5K3IA 1YRUA 2YYGA 2VF1A 1XFZA 4KSAA 3N0RA 1XFUA 4DZYA 4Q5CA 3BNHA 1R3BA 1U8VA 2E81A 2PNRA 3D1IA 3OWAA 4JEKA 4E01A 2WBIA 2ZO5A 3D9EA 1XFYA 3AFFA 5M4PA 3TZ4A 3OIBA 1WS9A 2BU6A 3FCJA 3II9A 4KS9A 2QR4A 1PK0A 3MPJA 2CJ8A 4E02A 2XS8A 3UBRA 3MMOA 2F6LA 1XFXA 1EGCA 1XFVA 2ZDXA 3D2RA 4FF4A 3TTBA 1JM6A 3HWCA 4L3XA 3VKHA 4V25A 4P13A 1QDBA 3SXQA 2YYIA 4FF1A 4FF3A 2PG0A 1RJ1A 5J71A 2BU7A 5K3HA 5M4NA 2VIGA 1GJVA 1RP3A 4JIZA 1GKZA 1K8TA 1GKXA 2BU8A 3Q22A 3MDEA 4G5EA 2Q8HA 3TORA 5B5WA 2OT4A 3TZ2A 2EBAA 3PFDA 2YYKA 4AI6A 1S26A 2BU2A 1X91A 2A1TA 3CRLA 4H7QA 3MPIA 5BRMA 2HJNA 3UU9A 3D6BA 3KMLA 4ZYJA 1XG2B 4RM7A 1Y0VA 1SC5A 2GBBA 2FP1A 4MPNA 3D9DA 5GJVE 4IRNA 2JBRA 4AKIA 1FS9A 4MP2A 1X90A 3BNFA 2JIFA 3EONA 4FZ4A 1UKWA 1Y8NA 2D29A 5B5VA 3BNGA 1BUCA 2FONA 3D9FA 3B96A 1RX0A 4P79A 2E0AA 3LGQA 4L1FA 2BTZA 3GM6A 2LFWA 4KCFA 3L1TA 2COLA 4NXLA 4F0XA 2EBHX 2RFQA 1FS7A 4L38A 4Q5BA 4N5FA 2DDHA 3NF4A 4LQQB 2R03A 3X0YA 2IX5A 4MP7A 2Z1QA 1ZOTA 2YYLA 3SCEA 3P4TA 3F29A 4M9AA 3TZ5A 1Y8OA 4G97A 2J7AA 2YYMA 4MPCA 5M4KA 1XFWA 1R2JA 1FS8A 2PO4A 1X8ZA 2JBTA 2AO2A 1SIRA 2REHA 3EOMA 1PI1A 3S7WA 3X29A 2CJ4A 2FP2A 1LVCA 3M9VA 3TZ0A 4V26A 3VADA 2R0NA 4Q17A 4E00A 1IVHA 1T9GA 2ZKJA 4W9UA 2XS1A 3Q0AA 3C3LA 3AFEA 4XVXA 1SK6A 2Q8IA 4AKHA 2OR0A 3GQTA 2RDZA 5M4MA 4LQSB 2JBSA 4X28C 3X0XA 2E80A 1IS2A 3CRKA 3Q24A 4X28A 2C12A 5J6AA 1GU6A 4U83A 3MDDA 4JIOA 2R0MA 2DVLA 4HR3A 4IV6A 4L3ZA 1YRTA 2R02A 4QICA 4O5MA 4KTOA 4MPEA 3SF6A 4DOYA 2EC5A 1K90A 2R05A 2IX6A 3LG1A 2RF7A 1EGDA 1EGEA 3FO3A 4HKRA 3OWMA 3D9GA 4Q0TA 4WJYA 2BU5A 3C2PA 4Q4UA 1OAHA 2CJ6A 3GNCA
chains in the Genus database with same CATH topology

3X29A 1XFYA 4FF2A 4AKGA 2FP2A 4KS9A 1LVCA 2GBBA 2YGWA 4KSFA 2QR4A 1PK0A 5GJVE 4AKIA 4FZ4A 2F6LA 3C3LA 1XFXA 3Q0AA 1SK6A 1XFVA 4FF4A 4AKHA 3VKHA 3VKGA 4P79A 1K93A 4FF3A 2LFWA 4FF1A 2COLA 4F0XA 2EBHX 3Q24A 3Q23A 2AZEA 5GJWE 2EBFX 4HKSA 1RP3A 1K8TA 3Q22A 1ZOTA 1YRTA 4QICA 3CE2A 2EC5A 1K90A 3C46A 4AI6A 4G97A 1YRUA 1S26A 1XFWA 4HKRA 2VF1A 1XFZA 2PO4A 3N0RA 1XFUA 3KMLA 4KSAA 3C2PA 2AO2A 1Y0VA 1SC5A 2FP1A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1S26 A;  1SK6 A;  1XFY A;  1K8T A;  1XFV A;  1XFW A;  1LVC A;  1Y0V A;  1XFZ A;  1YRT A;  1ZOT A;  1PK0 A;  1K93 A;  1XFU A;  2COL A;  1K90 A;  1XFX A;  1YRU A; 
#chains in the Genus database with same CATH topology
 2CJ7 A;  4FF2 A;  3R7K A;  4AKG A;  2YGW A;  2YYJ A;  2ZAF A;  4KSF A;  1Y8P A;  4J1V A;  4Q1O A;  5K3J A;  3SWO A;  2CX9 A;  4H85 A;  4L3Y A;  3MXL A;  4OO2 A;  4H81 A;  2Q8F A;  5BRK A;  2VR0 A;  2OJQ A;  3VKG A;  1SIQ A;  1JQI A;  2OEX A;  1K93 A;  2OEV A;  3BNJ A;  5K3G A;  2XQR B;  1UDY A;  5B6B A;  3Q23 A;  2AZE A;  5GJW E;  2EBF X;  2CJ5 A;  4HKS A;  3RKH A;  4ZXV A;  1W07 A;  3CE2 A;  2ZDY A;  3C46 A;  2Q8G A;  3MKH A;  2C0U A;  1RJ4 A;  2UXW A;  5K3I A;  1YRU A;  2YYG A;  2VF1 A;  1XFZ A;  4KSA A;  3N0R A;  1XFU A;  4DZY A;  4Q5C A;  3BNH A;  1R3B A;  1U8V A;  2E81 A;  2PNR A;  3D1I A;  3OWA A;  4JEK A;  4E01 A;  2WBI A;  2ZO5 A;  3D9E A;  1XFY A;  3AFF A;  5M4P A;  3TZ4 A;  3OIB A;  1WS9 A;  2BU6 A;  3FCJ A;  3II9 A;  4KS9 A;  2QR4 A;  1PK0 A;  3MPJ A;  2CJ8 A;  4E02 A;  2XS8 A;  3UBR A;  3MMO A;  2F6L A;  1XFX A;  1EGC A;  1XFV A;  2ZDX A;  3D2R A;  4FF4 A;  3TTB A;  1JM6 A;  3HWC A;  4L3X A;  3VKH A;  4V25 A;  4P13 A;  1QDB A;  3SXQ A;  2YYI A;  4FF1 A;  4FF3 A;  2PG0 A;  1RJ1 A;  5J71 A;  2BU7 A;  5K3H A;  5M4N A;  2VIG A;  1GJV A;  1RP3 A;  4JIZ A;  1GKZ A;  1K8T A;  1GKX A;  2BU8 A;  3Q22 A;  3MDE A;  4G5E A;  2Q8H A;  3TOR A;  5B5W A;  2OT4 A;  3TZ2 A;  2EBA A;  3PFD A;  2YYK A;  4AI6 A;  1S26 A;  2BU2 A;  1X91 A;  2A1T A;  3CRL A;  4H7Q A;  3MPI A;  5BRM A;  2HJN A;  3UU9 A;  3D6B A;  3KML A;  4ZYJ A;  1XG2 B;  4RM7 A;  1Y0V A;  1SC5 A;  2GBB A;  2FP1 A;  4MPN A;  3D9D A;  5GJV E;  4IRN A;  2JBR A;  4AKI A;  1FS9 A;  4MP2 A;  1X90 A;  3BNF A;  2JIF A;  3EON A;  4FZ4 A;  1UKW A;  1Y8N A;  2D29 A;  5B5V A;  3BNG A;  1BUC A;  2FON A;  3D9F A;  3B96 A;  1RX0 A;  4P79 A;  2E0A A;  3LGQ A;  4L1F A;  2BTZ A;  3GM6 A;  2LFW A;  4KCF A;  3L1T A;  2COL A;  4NXL A;  4F0X A;  2EBH X;  2RFQ A;  1FS7 A;  4L38 A;  4Q5B A;  4N5F A;  2DDH A;  3NF4 A;  4LQQ B;  2R03 A;  3X0Y A;  2IX5 A;  4MP7 A;  2Z1Q A;  1ZOT A;  2YYL A;  3SCE A;  3P4T A;  3F29 A;  4M9A A;  3TZ5 A;  1Y8O A;  4G97 A;  2J7A A;  2YYM A;  4MPC A;  5M4K A;  1XFW A;  1R2J A;  1FS8 A;  2PO4 A;  1X8Z A;  2JBT A;  2AO2 A;  1SIR A;  2REH A;  3EOM A;  1PI1 A;  3S7W A;  3X29 A;  2CJ4 A;  2FP2 A;  1LVC A;  3M9V A;  3TZ0 A;  4V26 A;  3VAD A;  2R0N A;  4Q17 A;  4E00 A;  1IVH A;  1T9G A;  2ZKJ A;  4W9U A;  2XS1 A;  3Q0A A;  3C3L A;  3AFE A;  4XVX A;  1SK6 A;  2Q8I A;  4AKH A;  2OR0 A;  3GQT A;  2RDZ A;  5M4M A;  4LQS B;  2JBS A;  4X28 C;  3X0X A;  2E80 A;  1IS2 A;  3CRK A;  3Q24 A;  4X28 A;  2C12 A;  5J6A A;  1GU6 A;  4U83 A;  3MDD A;  4JIO A;  2R0M A;  2DVL A;  4HR3 A;  4IV6 A;  4L3Z A;  1YRT A;  2R02 A;  4QIC A;  4O5M A;  4KTO A;  4MPE A;  3SF6 A;  4DOY A;  2EC5 A;  1K90 A;  2R05 A;  2IX6 A;  3LG1 A;  2RF7 A;  1EGD A;  1EGE A;  3FO3 A;  4HKR A;  3OWM A;  3D9G A;  4Q0T A;  4WJY A;  2BU5 A;  3C2P A;  4Q4U A;  1OAH A;  2CJ6 A;  3GNC A; 
#chains in the Genus database with same CATH homology
 3X29 A;  1XFY A;  4FF2 A;  4AKG A;  2FP2 A;  4KS9 A;  1LVC A;  2GBB A;  2YGW A;  4KSF A;  2QR4 A;  1PK0 A;  5GJV E;  4AKI A;  4FZ4 A;  2F6L A;  3C3L A;  1XFX A;  3Q0A A;  1SK6 A;  1XFV A;  4FF4 A;  4AKH A;  3VKH A;  3VKG A;  4P79 A;  1K93 A;  4FF3 A;  2LFW A;  4FF1 A;  2COL A;  4F0X A;  2EBH X;  3Q24 A;  3Q23 A;  2AZE A;  5GJW E;  2EBF X;  4HKS A;  1RP3 A;  1K8T A;  3Q22 A;  1ZOT A;  1YRT A;  4QIC A;  3CE2 A;  2EC5 A;  1K90 A;  3C46 A;  4AI6 A;  4G97 A;  1YRU A;  1S26 A;  1XFW A;  4HKR A;  2VF1 A;  1XFZ A;  2PO4 A;  3N0R A;  1XFU A;  3KML A;  4KSA A;  3C2P A;  2AO2 A;  1Y0V A;  1SC5 A;  2FP1 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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1PK0A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations