2AZEA

Structure of the rb c-terminal domain bound to an e2f1-dp1 heterodimer
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
149
structure length
149
Chain Sequence
FAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTVGGVF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
pubmed doi rcsb
molecule tags Cell cycle, transcription
source organism Homo sapiens
molecule keywords Transcription factor Dp-1
total genus 41
structure length 149
sequence length 149
ec nomenclature
pdb deposition date 2005-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08781 DP Transcription factor DP
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.80 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 2azeA01
2AZEA
chains in the Genus database with same CATH superfamily
1EGEA 3C3LA 3B96A 3OWMA 3X0YA 1RP3A 3TZ5A 3PFDA 3Q24A 2RF7A 2BU7A 3D9GA 4F0XA 3M9VA 5J6AA 2PG0A 4KCFA 5GJVE 1XFWA 4FF4A 3VKGA 2OEXA 1Y0VA 2BU2A 4V25A 1JM6A 1LVCA 2VF1A 2ZO5A 3GNCA 3HWCA 2Q8IA 2FONA 3NF4A 4H7QA 1RJ1A 2VIGA 4E02A 1IS2A 2YYJA 4JEKA 1K8TA 1GKXA 3L1TA 2BU6A 2E81A 3GM6A 2OR0A 4H81A 3S7WA 3X29A 3MXLA 2IX5A 4FF2A 1UDYA 2OT4A 4E00A 2EC5A 2CJ8A 2EBHX 1OAHA 2Z1QA 5K3HA 1FS7A 2JBRA 2ZDXA 3D9DA 3BNHA 3Q22A 4KSAA 5B6BA 1JQIA 4AKGA 1FS8A 4HKRA 3C2PA 1Y8PA 3D1IA 2F6LA 2XS1A 1R3BA 2YYLA 1S26A 2YYGA 4O5MA 3LGQA 4W9UA 3TTBA 3VADA 1XFVA 4AI6A 2ZKJA 2HJNA 3C46A 3D2RA 1K93A 4NXLA 1U8VA 4ZXVA 3RKHA 4X28A 4H85A 3Q23A 1UKWA 1X8ZA 2OJQA 2RFQA 4J1VA 4RM7A 5BRMA 4MPCA 4P79A 2YGWA 2R0MA 1RX0A 2C0UA 1PI1A 3II9A 4KSFA 4Q5BA 4M9AA 1EGDA 2D29A 4P13A 3D9EA 4DZYA 2A1TA 4L38A 4L3YA 4Q1OA 4ZYJA 3SWOA 1FS9A 1GKZA 1XFZA 2AO2A 1XFYA 2QR4A 2RDZA 3BNGA 4DOYA 2CJ7A 1QDBA 3N0RA 3TORA 1XFUA 2FP2A 2DVLA 3AFFA 3CE2A 1IVHA 2R05A 3D9FA 1SIRA 3F29A 1X91A 2BU5A 4AKIA 5M4KA 2CX9A 3EOMA 3EONA 4QICA 2CJ5A 2VR0A 3MKHA 3TZ0A 2FP1A 4XVXA 4HR3A 2UXWA 3BNJA 3Q0AA 3OWAA 2GBBA 2ZDYA 2XQRB 4LQQB 3LG1A 4U83A 1W07A 3BNFA 5B5VA 2R02A 5K3IA 1GU6A 1SIQA 4MPEA 2YYIA 2AZEA 1BUCA 2EBFX 2OEVA 4HKSA 2EBAA 4G5EA 1XG2B 4Q5CA 2E0AA 2ZAFA 4L1FA 4E01A 3TZ2A 4N5FA 3SF6A 5B5WA 1XFXA 4LQSB 5K3GA 1SC5A 4FZ4A 4MP2A 3UU9A 5J71A 4V26A 3AFEA 5GJWE 5M4NA 2JBTA 1Y8NA 2Q8FA 2BU8A 2PO4A 3FCJA 2CJ6A 3MDEA 3SXQA 4IRNA 4FF3A 1RJ4A 4AKHA 1WS9A 3X0XA 3KMLA 2LFWA 4X28C 3TZ4A 3CRKA 2REHA 5M4PA 2YYMA 4KTOA 4L3XA 4Q0TA 1T9GA 3MPJA 1GJVA 2JIFA 2R0NA 3VKHA 5K3JA 4Q17A 1R2JA 3CRLA 2WBIA 2C12A 3GQTA 4MPNA 4MP7A 4G97A 3FO3A 3UBRA 2BTZA 2Q8HA 3MMOA 4Q4UA 4KS9A 2CJ4A 2R03A 3R7KA 3MPIA 1X90A 4FF1A 2PNRA 1PK0A 1K90A 2JBSA 2YYKA 1EGCA 1Y8OA 3P4TA 4IV6A 4JIOA 2Q8GA 5M4MA 1SK6A 2E80A 4JIZA 2DDHA 2J7AA 2IX6A 3MDDA 4L3ZA 5BRKA 4OO2A 4WJYA 3OIBA 2XS8A 3SCEA 3D6BA
chains in the Genus database with same CATH topology
3CE2A 3Q22A 2PO4A 4KSAA 4FF3A 4AKIA 3C3LA 4AKHA 4AKGA 4HKRA 3KMLA 2LFWA 4QICA 3C2PA 1RP3A 2F6LA 2FP1A 3Q24A 1S26A 3Q0AA 2GBBA 4F0XA 1XFVA 4AI6A 5GJVE 3VKHA 1XFWA 4FF4A 3N0RA 3C46A 1K93A 3VKGA 1Y0VA 4G97A 2AZEA 1LVCA 2VF1A 2EBFX 3Q23A 4HKSA 4KS9A 4P79A 2YGWA 4KSFA 1K8TA 4FF1A 1PK0A 1K90A 3X29A 1SK6A 1XFXA 4FF2A 1XFZA 2AO2A 1SC5A 4FZ4A 1XFYA 2QR4A 2EC5A 2FP2A 5GJWE 2EBHX 1XFUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AZE A; 
#chains in the Genus database with same CATH topology
 1EGE A;  3C3L A;  3B96 A;  3OWM A;  3X0Y A;  1RP3 A;  3TZ5 A;  3PFD A;  3Q24 A;  2RF7 A;  2BU7 A;  3D9G A;  4F0X A;  3M9V A;  5J6A A;  2PG0 A;  4KCF A;  5GJV E;  1XFW A;  4FF4 A;  3VKG A;  2OEX A;  1Y0V A;  2BU2 A;  4V25 A;  1JM6 A;  1LVC A;  2VF1 A;  2ZO5 A;  3GNC A;  3HWC A;  2Q8I A;  2FON A;  3NF4 A;  4H7Q A;  1RJ1 A;  2VIG A;  4E02 A;  1IS2 A;  2YYJ A;  4JEK A;  1K8T A;  1GKX A;  3L1T A;  2BU6 A;  2E81 A;  3GM6 A;  2OR0 A;  4H81 A;  3S7W A;  3X29 A;  3MXL A;  2IX5 A;  4FF2 A;  1UDY A;  2OT4 A;  4E00 A;  2EC5 A;  2CJ8 A;  2EBH X;  1OAH A;  2Z1Q A;  5K3H A;  1FS7 A;  2JBR A;  2ZDX A;  3D9D A;  3BNH A;  3Q22 A;  4KSA A;  5B6B A;  1JQI A;  4AKG A;  1FS8 A;  4HKR A;  3C2P A;  1Y8P A;  3D1I A;  2F6L A;  2XS1 A;  1R3B A;  2YYL A;  1S26 A;  2YYG A;  4O5M A;  3LGQ A;  4W9U A;  3TTB A;  3VAD A;  1XFV A;  4AI6 A;  2ZKJ A;  2HJN A;  3C46 A;  3D2R A;  1K93 A;  4NXL A;  1U8V A;  4ZXV A;  3RKH A;  4X28 A;  4H85 A;  3Q23 A;  1UKW A;  1X8Z A;  2OJQ A;  2RFQ A;  4J1V A;  4RM7 A;  5BRM A;  4MPC A;  4P79 A;  2YGW A;  2R0M A;  1RX0 A;  2C0U A;  1PI1 A;  3II9 A;  4KSF A;  4Q5B A;  4M9A A;  1EGD A;  2D29 A;  4P13 A;  3D9E A;  4DZY A;  2A1T A;  4L38 A;  4L3Y A;  4Q1O A;  4ZYJ A;  3SWO A;  1FS9 A;  1GKZ A;  1XFZ A;  2AO2 A;  1XFY A;  2QR4 A;  2RDZ A;  3BNG A;  4DOY A;  2CJ7 A;  1QDB A;  3N0R A;  3TOR A;  1XFU A;  2FP2 A;  2DVL A;  3AFF A;  3CE2 A;  1IVH A;  2R05 A;  3D9F A;  1SIR A;  3F29 A;  1X91 A;  2BU5 A;  4AKI A;  5M4K A;  2CX9 A;  3EOM A;  3EON A;  4QIC A;  2CJ5 A;  2VR0 A;  3MKH A;  3TZ0 A;  2FP1 A;  4XVX A;  4HR3 A;  2UXW A;  3BNJ A;  3Q0A A;  3OWA A;  2GBB A;  2ZDY A;  2XQR B;  4LQQ B;  3LG1 A;  4U83 A;  1W07 A;  3BNF A;  5B5V A;  2R02 A;  5K3I A;  1GU6 A;  1SIQ A;  4MPE A;  2YYI A;  2AZE A;  1BUC A;  2EBF X;  2OEV A;  4HKS A;  2EBA A;  4G5E A;  1XG2 B;  4Q5C A;  2E0A A;  2ZAF A;  4L1F A;  4E01 A;  3TZ2 A;  4N5F A;  3SF6 A;  5B5W A;  1XFX A;  4LQS B;  5K3G A;  1SC5 A;  4FZ4 A;  4MP2 A;  3UU9 A;  5J71 A;  4V26 A;  3AFE A;  5GJW E;  5M4N A;  2JBT A;  1Y8N A;  2Q8F A;  2BU8 A;  2PO4 A;  3FCJ A;  2CJ6 A;  3MDE A;  3SXQ A;  4IRN A;  4FF3 A;  1RJ4 A;  4AKH A;  1WS9 A;  3X0X A;  3KML A;  2LFW A;  4X28 C;  3TZ4 A;  3CRK A;  2REH A;  5M4P A;  2YYM A;  4KTO A;  4L3X A;  4Q0T A;  1T9G A;  3MPJ A;  1GJV A;  2JIF A;  2R0N A;  3VKH A;  5K3J A;  4Q17 A;  1R2J A;  3CRL A;  2WBI A;  2C12 A;  3GQT A;  4MPN A;  4MP7 A;  4G97 A;  3FO3 A;  3UBR A;  2BTZ A;  2Q8H A;  3MMO A;  4Q4U A;  4KS9 A;  2CJ4 A;  2R03 A;  3R7K A;  3MPI A;  1X90 A;  4FF1 A;  2PNR A;  1PK0 A;  1K90 A;  2JBS A;  2YYK A;  1EGC A;  1Y8O A;  3P4T A;  4IV6 A;  4JIO A;  2Q8G A;  5M4M A;  1SK6 A;  2E80 A;  4JIZ A;  2DDH A;  2J7A A;  2IX6 A;  3MDD A;  4L3Z A;  5BRK A;  4OO2 A;  4WJY A;  3OIB A;  2XS8 A;  3SCE A;  3D6B A; 
#chains in the Genus database with same CATH homology
 3CE2 A;  3Q22 A;  2PO4 A;  4KSA A;  4FF3 A;  4AKI A;  3C3L A;  4AKH A;  4AKG A;  4HKR A;  3KML A;  2LFW A;  4QIC A;  3C2P A;  1RP3 A;  2F6L A;  2FP1 A;  3Q24 A;  1S26 A;  3Q0A A;  2GBB A;  4F0X A;  1XFV A;  4AI6 A;  5GJV E;  3VKH A;  1XFW A;  4FF4 A;  3N0R A;  3C46 A;  1K93 A;  3VKG A;  1Y0V A;  4G97 A;  2AZE A;  1LVC A;  2VF1 A;  2EBF X;  3Q23 A;  4HKS A;  4KS9 A;  4P79 A;  2YGW A;  4KSF A;  1K8T A;  4FF1 A;  1PK0 A;  1K90 A;  3X29 A;  1SK6 A;  1XFX A;  4FF2 A;  1XFZ A;  2AO2 A;  1SC5 A;  4FZ4 A;  1XFY A;  2QR4 A;  2EC5 A;  2FP2 A;  5GJW E;  2EBH X;  1XFU A; 
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similar chains in the Genus database (?% sequence similarity)
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