2AZEA

Structure of the rb c-terminal domain bound to an e2f1-dp1 heterodimer
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
149
structure length
149
Chain Sequence
FAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTVGGVF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
pubmed doi rcsb
molecule tags Cell cycle, transcription
source organism Homo sapiens
molecule keywords Transcription factor Dp-1
total genus 41
structure length 149
sequence length 149
ec nomenclature
pdb deposition date 2005-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08781 DP Transcription factor DP
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.80 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 2azeA01
2AZEA
chains in the Genus database with same CATH superfamily
1U8VA 2C0UA 3UBRA 3LGQA 4L38A 3VADA 5BRKA 5B6BA 3MDDA 3VKGA 3OWMA 4HR3A 1XFUA 1R3BA 2CJ6A 4KS9A 3X0XA 1GKXA 2YYGA 3S7WA 2EBAA 2R02A 3KMLA 1FS7A 2AZEA 3P4TA 4M9AA 1X90A 2LFWA 4G97A 4OO2A 3C46A 1LVCA 3FCJA 3BNGA 5J71A 2E80A 4AKHA 5B5VA 3AFFA 2EBHX 2BU2A 3D9FA 3Q23A 4U83A 2IX6A 3MKHA 1Y8OA 3EOMA 4L3XA 2DVLA 2IX5A 2Q8FA 1IS2A 3CE2A 1T9GA 2VF1A 2VR0A 3F29A 4IV6A 3GM6A 1GJVA 1W07A 4L3YA 4O5MA 2BU6A 5B5WA 1XG2B 2F6LA 2J7AA 2E81A 2VIGA 2YYJA 3D1IA 3L1TA 2FP2A 4MPEA 2FP1A 4Q17A 4Q1OA 4X28A 3D9DA 4FZ4A 3LG1A 2BU5A 4V25A 2CJ5A 3OIBA 2OR0A 3GNCA 2R0MA 2REHA 4X28C 4AKGA 1S26A 4W9UA 3RKHA 1RX0A 4P13A 3Q0AA 2YYMA 5M4KA 4Q5BA 3TZ4A 3BNFA 4LQSB 3TZ5A 4G5EA 2PNRA 3BNHA 2YYKA 3MPJA 4Q4UA 4F0XA 3BNJA 3SWOA 4IRNA 3C2PA 2XS1A 3II9A 4H81A 3SF6A 3OWAA 1Y0VA 3SCEA 3N0RA 5GJWE 3D9GA 4MP7A 2QR4A 4AI6A 4KTOA 2YYLA 1PK0A 1R2JA 2R03A 2CJ4A 1RJ4A 1FS9A 2OJQA 2RDZA 2YYIA 4Q5CA 2JBTA 3D6BA 4HKSA 1EGEA 3GQTA 4FF2A 4J1VA 1BUCA 2Z1QA 4JEKA 3TTBA 1RP3A 4E00A 1UKWA 1GKZA 4FF3A 2ZKJA 1SIRA 4L3ZA 1UDYA 2HJNA 2WBIA 1XFWA 2Q8HA 4JIZA 1PI1A 2RF7A 4MPCA 4KSFA 2R05A 1JM6A 2RFQA 4QICA 3CRKA 3B96A 1XFZA 2OEVA 4H85A 5K3GA 3MMOA 5M4NA 2PG0A 1K8TA 1RJ1A 2CJ7A 4ZYJA 4WJYA 1GU6A 2D29A 3FO3A 5BRMA 2GBBA 4V26A 3EONA 1OAHA 1X8ZA 3TORA 4DZYA 3MXLA 3HWCA 3CRLA 3NF4A 4KCFA 4ZXVA 3D2RA 2EC5A 3Q22A 2CJ8A 2AO2A 2ZDYA 2JBRA 1K90A 2OEXA 4N5FA 1Y8NA 2ZDXA 3MDEA 4NXLA 3VKHA 4Q0TA 1K93A 1XFVA 1WS9A 2CX9A 2A1TA 2Q8GA 1QDBA 1Y8PA 1SIQA 2FONA 5K3IA 1SC5A 5K3HA 1SK6A 3PFDA 3UU9A 4XVXA 2C12A 2ZAFA 2PO4A 5J6AA 2R0NA 1XFYA 2E0AA 4RM7A 3C3LA 4L1FA 3MPIA 1EGDA 3D9EA 2BU8A 3R7KA 5K3JA 3X29A 3M9VA 3AFEA 3TZ0A 4MP2A 3TZ2A 2EBFX 3X0YA 1XFXA 2XS8A 4E02A 1IVHA 4JIOA 4LQQB 1FS8A 2JIFA 4H7QA 4FF1A 2Q8IA 4KSAA 4FF4A 3Q24A 2ZO5A 2DDHA 2BTZA 2JBSA 5M4PA 4DOYA 4E01A 1X91A 4MPNA 1EGCA 4HKRA 2OT4A 3SXQA 2UXWA 1JQIA 2XQRB 2YGWA 4P79A 5M4MA 4AKIA 5GJVE 2BU7A
chains in the Genus database with same CATH topology
2FP1A 3VKHA 4HKSA 1K93A 4FF2A 1XFVA 4FZ4A 3VKGA 4KS9A 1XFUA 1SC5A 1RP3A 1SK6A 4FF3A 4AKGA 1S26A 1XFWA 3Q0AA 2PO4A 3KMLA 1XFYA 2AZEA 3C3LA 2LFWA 4G97A 3C46A 1LVCA 4KSFA 4AKHA 4QICA 3Q23A 2EBHX 3X29A 1XFZA 4F0XA 2EBFX 1XFXA 4FF4A 1K8TA 4FF1A 3C2PA 4KSAA 3Q24A 3CE2A 2VF1A 2GBBA 1Y0VA 3N0RA 5GJWE 4HKRA 2QR4A 2YGWA 4AKIA 3Q22A 2F6LA 4P79A 4AI6A 1PK0A 2EC5A 5GJVE 2AO2A 2FP2A 1K90A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AZE A; 
#chains in the Genus database with same CATH topology
 1U8V A;  2C0U A;  3UBR A;  3LGQ A;  4L38 A;  3VAD A;  5BRK A;  5B6B A;  3MDD A;  3VKG A;  3OWM A;  4HR3 A;  1XFU A;  1R3B A;  2CJ6 A;  4KS9 A;  3X0X A;  1GKX A;  2YYG A;  3S7W A;  2EBA A;  2R02 A;  3KML A;  1FS7 A;  2AZE A;  3P4T A;  4M9A A;  1X90 A;  2LFW A;  4G97 A;  4OO2 A;  3C46 A;  1LVC A;  3FCJ A;  3BNG A;  5J71 A;  2E80 A;  4AKH A;  5B5V A;  3AFF A;  2EBH X;  2BU2 A;  3D9F A;  3Q23 A;  4U83 A;  2IX6 A;  3MKH A;  1Y8O A;  3EOM A;  4L3X A;  2DVL A;  2IX5 A;  2Q8F A;  1IS2 A;  3CE2 A;  1T9G A;  2VF1 A;  2VR0 A;  3F29 A;  4IV6 A;  3GM6 A;  1GJV A;  1W07 A;  4L3Y A;  4O5M A;  2BU6 A;  5B5W A;  1XG2 B;  2F6L A;  2J7A A;  2E81 A;  2VIG A;  2YYJ A;  3D1I A;  3L1T A;  2FP2 A;  4MPE A;  2FP1 A;  4Q17 A;  4Q1O A;  4X28 A;  3D9D A;  4FZ4 A;  3LG1 A;  2BU5 A;  4V25 A;  2CJ5 A;  3OIB A;  2OR0 A;  3GNC A;  2R0M A;  2REH A;  4X28 C;  4AKG A;  1S26 A;  4W9U A;  3RKH A;  1RX0 A;  4P13 A;  3Q0A A;  2YYM A;  5M4K A;  4Q5B A;  3TZ4 A;  3BNF A;  4LQS B;  3TZ5 A;  4G5E A;  2PNR A;  3BNH A;  2YYK A;  3MPJ A;  4Q4U A;  4F0X A;  3BNJ A;  3SWO A;  4IRN A;  3C2P A;  2XS1 A;  3II9 A;  4H81 A;  3SF6 A;  3OWA A;  1Y0V A;  3SCE A;  3N0R A;  5GJW E;  3D9G A;  4MP7 A;  2QR4 A;  4AI6 A;  4KTO A;  2YYL A;  1PK0 A;  1R2J A;  2R03 A;  2CJ4 A;  1RJ4 A;  1FS9 A;  2OJQ A;  2RDZ A;  2YYI A;  4Q5C A;  2JBT A;  3D6B A;  4HKS A;  1EGE A;  3GQT A;  4FF2 A;  4J1V A;  1BUC A;  2Z1Q A;  4JEK A;  3TTB A;  1RP3 A;  4E00 A;  1UKW A;  1GKZ A;  4FF3 A;  2ZKJ A;  1SIR A;  4L3Z A;  1UDY A;  2HJN A;  2WBI A;  1XFW A;  2Q8H A;  4JIZ A;  1PI1 A;  2RF7 A;  4MPC A;  4KSF A;  2R05 A;  1JM6 A;  2RFQ A;  4QIC A;  3CRK A;  3B96 A;  1XFZ A;  2OEV A;  4H85 A;  5K3G A;  3MMO A;  5M4N A;  2PG0 A;  1K8T A;  1RJ1 A;  2CJ7 A;  4ZYJ A;  4WJY A;  1GU6 A;  2D29 A;  3FO3 A;  5BRM A;  2GBB A;  4V26 A;  3EON A;  1OAH A;  1X8Z A;  3TOR A;  4DZY A;  3MXL A;  3HWC A;  3CRL A;  3NF4 A;  4KCF A;  4ZXV A;  3D2R A;  2EC5 A;  3Q22 A;  2CJ8 A;  2AO2 A;  2ZDY A;  2JBR A;  1K90 A;  2OEX A;  4N5F A;  1Y8N A;  2ZDX A;  3MDE A;  4NXL A;  3VKH A;  4Q0T A;  1K93 A;  1XFV A;  1WS9 A;  2CX9 A;  2A1T A;  2Q8G A;  1QDB A;  1Y8P A;  1SIQ A;  2FON A;  5K3I A;  1SC5 A;  5K3H A;  1SK6 A;  3PFD A;  3UU9 A;  4XVX A;  2C12 A;  2ZAF A;  2PO4 A;  5J6A A;  2R0N A;  1XFY A;  2E0A A;  4RM7 A;  3C3L A;  4L1F A;  3MPI A;  1EGD A;  3D9E A;  2BU8 A;  3R7K A;  5K3J A;  3X29 A;  3M9V A;  3AFE A;  3TZ0 A;  4MP2 A;  3TZ2 A;  2EBF X;  3X0Y A;  1XFX A;  2XS8 A;  4E02 A;  1IVH A;  4JIO A;  4LQQ B;  1FS8 A;  2JIF A;  4H7Q A;  4FF1 A;  2Q8I A;  4KSA A;  4FF4 A;  3Q24 A;  2ZO5 A;  2DDH A;  2BTZ A;  2JBS A;  5M4P A;  4DOY A;  4E01 A;  1X91 A;  4MPN A;  1EGC A;  4HKR A;  2OT4 A;  3SXQ A;  2UXW A;  1JQI A;  2XQR B;  2YGW A;  4P79 A;  5M4M A;  4AKI A;  5GJV E;  2BU7 A; 
#chains in the Genus database with same CATH homology
 2FP1 A;  3VKH A;  4HKS A;  1K93 A;  4FF2 A;  1XFV A;  4FZ4 A;  3VKG A;  4KS9 A;  1XFU A;  1SC5 A;  1RP3 A;  1SK6 A;  4FF3 A;  4AKG A;  1S26 A;  1XFW A;  3Q0A A;  2PO4 A;  3KML A;  1XFY A;  2AZE A;  3C3L A;  2LFW A;  4G97 A;  3C46 A;  1LVC A;  4KSF A;  4AKH A;  4QIC A;  3Q23 A;  2EBH X;  3X29 A;  1XFZ A;  4F0X A;  2EBF X;  1XFX A;  4FF4 A;  1K8T A;  4FF1 A;  3C2P A;  4KSA A;  3Q24 A;  3CE2 A;  2VF1 A;  2GBB A;  1Y0V A;  3N0R A;  5GJW E;  4HKR A;  2QR4 A;  2YGW A;  4AKI A;  3Q22 A;  2F6L A;  4P79 A;  4AI6 A;  1PK0 A;  2EC5 A;  5GJV E;  2AO2 A;  2FP2 A;  1K90 A; 
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similar chains in the Genus database (?% sequence similarity)
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