2F6L | Genus

Total Genus 70

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	70
sequence length	166
structure length	166
Chain Sequence	DGTSQLAELVDAAAERLEVADPVAAFKWRAQLPIEDSGRVEQQLAKLGEDARSQHIDPDYVTRVFDDQIRATEAIEYSRFSDWKLNPASAPPEPPDLSASRSAIDSLNNRMLSQIWSHWSLLSAPSCAAQLDRAKRDIVRSRHLDSLYQRALTTATQSYCQALPPA

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Isomerase
source organism	Mycobacterium tuberculosis
publication title	Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids. pubmed doi rcsb
molecule keywords	Chorismate mutase
total genus	70
structure length	166
sequence length	166
chains with identical sequence	B
ec nomenclature	ec 5.4.99.5: Chorismate mutase.
pdb deposition date	2005-11-29

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01817	CM_2	Chorismate mutase type II

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.140.170	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A; domain 3	Butyryl-CoA Dehydrogenase, subunit A; domain 3	2f6lA00

2GBBA 2F6LA 2AO2A 2FP2A 2FP1A
chains in the Genus database with same CATH superfamily

1K8TA 1BUCA 1FS8A 2BU2A 1U8VA 3CRLA 3OWAA 3GQTA 2YYIA 2R03A 2IX6A 3D9DA 3PFDA 1RP3A 2QR4A 2Q8FA 4L1FA 4L3ZA 1XFWA 2FP1A 3TORA 3F29A 1RJ4A 2OJQA 1UKWA 3M9VA 3AFEA 3S7WA 4Q4UA 2JIFA 4J1VA 2CJ7A 2HJNA 2YYJA 4KTOA 4MP2A 3SCEA 4E00A 2R0NA 4E01A 4AKGA 5M4KA 1Y0VA 3C3LA 1R3BA 1SK6A 2C0UA 2CJ4A 3EOMA 1Y8NA 1RJ1A 3R7KA 4E02A 4F0XA 2BU8A 4KCFA 5GJWE 1GJVA 1XFUA 1W07A 4LQSB 4P13A 4AKHA 1R2JA 3VADA 5J6AA 1OAHA 1LVCA 1QDBA 4Q1OA 3OWMA 1X8ZA 2BU7A 2CJ8A 2XS1A 4H7QA 4ZXVA 3TZ0A 4MPNA 2YYMA 4N5FA 3L1TA 1JM6A 4W9UA 4X28C 3MMOA 2YGWA 1RX0A 1SC5A 4FF3A 2IX5A 1S26A 1EGCA 3NF4A 2ZDXA 1GKXA 4MPCA 2R0MA 2REHA 2AZEA 3CRKA 4L38A 3SXQA 1UDYA 2VF1A 3Q22A 4FF1A 1Y8OA 4FZ4A 1T9GA 2YYKA 5B6BA 4QICA 4JIOA 4FF2A 2PNRA 1SIRA 2Q8HA 3D9EA 2FP2A 1K93A 2A1TA 3N0RA 2DDHA 5K3HA 2OEVA 3UU9A 3GNCA 3D9FA 1FS7A 2Q8GA 1IVHA 4DZYA 4IRNA 4L3YA 3MKHA 3MPIA 4HR3A 4XVXA 5K3IA 4FF4A 4AKIA 2ZDYA 4OO2A 1XFZA 3BNGA 3SWOA 4Q17A 2JBRA 3D9GA 2ZAFA 1IS2A 2WBIA 1XFVA 3BNHA 2E80A 3TTBA 2PO4A 4DOYA 3RKHA 5B5WA 2JBSA 2OEXA 3HWCA 2OT4A 3D6BA 4P79A 4H85A 1GU6A 2ZO5A 4X28A 2XS8A 2UXWA 2YYLA 3TZ2A 3MXLA 4HKRA 5J71A 2ZKJA 3FCJA 4ZYJA 3D2RA 4KSAA 2RF7A 1PI1A 4LQQB 2C12A 5M4NA 4Q0TA 2LFWA 3VKGA 4G5EA 3GM6A 2CJ5A 3FO3A 2FONA 3BNFA 4KSFA 3C2PA 4IV6A 2EC5A 1X90A 4AI6A 1FS9A 1Y8PA 3BNJA 2R05A 1XFXA 3EONA 1JQIA 1EGDA 1SIQA 2E81A 3B96A 3P4TA 4O5MA 4RM7A 4M9AA 1EGEA 3MPJA 3Q24A 3OIBA 1XFYA 4JIZA 2BTZA 2Z1QA 4V25A 2DVLA 3CE2A 5M4PA 4V26A 2BU6A 4JEKA 4U83A 1GKZA 4KS9A 3LGQA 4HKSA 2F6LA 3Q0AA 3VKHA 2R02A 4MP7A 2PG0A 3II9A 2BU5A 5BRMA 1K90A 4Q5BA 3TZ5A 3TZ4A 3UBRA 3X29A 3D1IA 5M4MA 2OR0A 2J7AA 1WS9A 3LG1A 3MDDA 2E0AA 4H81A 5BRKA 4NXLA 1PK0A 2EBAA 1X91A 2EBFX 4L3XA 1XG2B 3AFFA 5K3GA 2YYGA 3MDEA 4G97A 2RDZA 2AO2A 2EBHX 4WJYA 3C46A 5B5VA 3SF6A 4Q5CA 3X0YA 2XQRB 2CX9A 2JBTA 3Q23A 2VIGA 2GBBA 2RFQA 2VR0A 2D29A 5K3JA 5GJVE 3X0XA 2Q8IA 4MPEA 3KMLA 2CJ6A
chains in the Genus database with same CATH topology

1K8TA 2YGWA 1SC5A 4FF3A 4KS9A 4HKSA 4P79A 1S26A 2F6LA 3Q0AA 3VKHA 1RP3A 2QR4A 1XFWA 3X29A 2FP1A 4HKRA 1K90A 3Q22A 4FF1A 2VF1A 4KSAA 4FZ4A 4FF2A 4QICA 2LFWA 3VKGA 2FP2A 4KSFA 1Y0VA 1PK0A 1K93A 3C3LA 1SK6A 4F0XA 3N0RA 3CE2A 3C2PA 2EBFX 2EC5A 3C46A 4G97A 1XFUA 2AO2A 2EBHX 5GJWE 4AKGA 4AI6A 1XFXA 4FF4A 4AKHA 3Q23A 4AKIA 1LVCA 2GBBA 1XFZA 3Q24A 1XFYA 5GJVE 3KMLA 1XFVA 2AZEA 2PO4A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 2GBB A;  2F6L A;  2AO2 A;  2FP2 A;  2FP1 A; 
#chains in the Genus database with same CATH topology
 1K8T A;  1BUC A;  1FS8 A;  2BU2 A;  1U8V A;  3CRL A;  3OWA A;  3GQT A;  2YYI A;  2R03 A;  2IX6 A;  3D9D A;  3PFD A;  1RP3 A;  2QR4 A;  2Q8F A;  4L1F A;  4L3Z A;  1XFW A;  2FP1 A;  3TOR A;  3F29 A;  1RJ4 A;  2OJQ A;  1UKW A;  3M9V A;  3AFE A;  3S7W A;  4Q4U A;  2JIF A;  4J1V A;  2CJ7 A;  2HJN A;  2YYJ A;  4KTO A;  4MP2 A;  3SCE A;  4E00 A;  2R0N A;  4E01 A;  4AKG A;  5M4K A;  1Y0V A;  3C3L A;  1R3B A;  1SK6 A;  2C0U A;  2CJ4 A;  3EOM A;  1Y8N A;  1RJ1 A;  3R7K A;  4E02 A;  4F0X A;  2BU8 A;  4KCF A;  5GJW E;  1GJV A;  1XFU A;  1W07 A;  4LQS B;  4P13 A;  4AKH A;  1R2J A;  3VAD A;  5J6A A;  1OAH A;  1LVC A;  1QDB A;  4Q1O A;  3OWM A;  1X8Z A;  2BU7 A;  2CJ8 A;  2XS1 A;  4H7Q A;  4ZXV A;  3TZ0 A;  4MPN A;  2YYM A;  4N5F A;  3L1T A;  1JM6 A;  4W9U A;  4X28 C;  3MMO A;  2YGW A;  1RX0 A;  1SC5 A;  4FF3 A;  2IX5 A;  1S26 A;  1EGC A;  3NF4 A;  2ZDX A;  1GKX A;  4MPC A;  2R0M A;  2REH A;  2AZE A;  3CRK A;  4L38 A;  3SXQ A;  1UDY A;  2VF1 A;  3Q22 A;  4FF1 A;  1Y8O A;  4FZ4 A;  1T9G A;  2YYK A;  5B6B A;  4QIC A;  4JIO A;  4FF2 A;  2PNR A;  1SIR A;  2Q8H A;  3D9E A;  2FP2 A;  1K93 A;  2A1T A;  3N0R A;  2DDH A;  5K3H A;  2OEV A;  3UU9 A;  3GNC A;  3D9F A;  1FS7 A;  2Q8G A;  1IVH A;  4DZY A;  4IRN A;  4L3Y A;  3MKH A;  3MPI A;  4HR3 A;  4XVX A;  5K3I A;  4FF4 A;  4AKI A;  2ZDY A;  4OO2 A;  1XFZ A;  3BNG A;  3SWO A;  4Q17 A;  2JBR A;  3D9G A;  2ZAF A;  1IS2 A;  2WBI A;  1XFV A;  3BNH A;  2E80 A;  3TTB A;  2PO4 A;  4DOY A;  3RKH A;  5B5W A;  2JBS A;  2OEX A;  3HWC A;  2OT4 A;  3D6B A;  4P79 A;  4H85 A;  1GU6 A;  2ZO5 A;  4X28 A;  2XS8 A;  2UXW A;  2YYL A;  3TZ2 A;  3MXL A;  4HKR A;  5J71 A;  2ZKJ A;  3FCJ A;  4ZYJ A;  3D2R A;  4KSA A;  2RF7 A;  1PI1 A;  4LQQ B;  2C12 A;  5M4N A;  4Q0T A;  2LFW A;  3VKG A;  4G5E A;  3GM6 A;  2CJ5 A;  3FO3 A;  2FON A;  3BNF A;  4KSF A;  3C2P A;  4IV6 A;  2EC5 A;  1X90 A;  4AI6 A;  1FS9 A;  1Y8P A;  3BNJ A;  2R05 A;  1XFX A;  3EON A;  1JQI A;  1EGD A;  1SIQ A;  2E81 A;  3B96 A;  3P4T A;  4O5M A;  4RM7 A;  4M9A A;  1EGE A;  3MPJ A;  3Q24 A;  3OIB A;  1XFY A;  4JIZ A;  2BTZ A;  2Z1Q A;  4V25 A;  2DVL A;  3CE2 A;  5M4P A;  4V26 A;  2BU6 A;  4JEK A;  4U83 A;  1GKZ A;  4KS9 A;  3LGQ A;  4HKS A;  2F6L A;  3Q0A A;  3VKH A;  2R02 A;  4MP7 A;  2PG0 A;  3II9 A;  2BU5 A;  5BRM A;  1K90 A;  4Q5B A;  3TZ5 A;  3TZ4 A;  3UBR A;  3X29 A;  3D1I A;  5M4M A;  2OR0 A;  2J7A A;  1WS9 A;  3LG1 A;  3MDD A;  2E0A A;  4H81 A;  5BRK A;  4NXL A;  1PK0 A;  2EBA A;  1X91 A;  2EBF X;  4L3X A;  1XG2 B;  3AFF A;  5K3G A;  2YYG A;  3MDE A;  4G97 A;  2RDZ A;  2AO2 A;  2EBH X;  4WJY A;  3C46 A;  5B5V A;  3SF6 A;  4Q5C A;  3X0Y A;  2XQR B;  2CX9 A;  2JBT A;  3Q23 A;  2VIG A;  2GBB A;  2RFQ A;  2VR0 A;  2D29 A;  5K3J A;  5GJV E;  3X0X A;  2Q8I A;  4MPE A;  3KML A;  2CJ6 A; 
#chains in the Genus database with same CATH homology
 1K8T A;  2YGW A;  1SC5 A;  4FF3 A;  4KS9 A;  4HKS A;  4P79 A;  1S26 A;  2F6L A;  3Q0A A;  3VKH A;  1RP3 A;  2QR4 A;  1XFW A;  3X29 A;  2FP1 A;  4HKR A;  1K90 A;  3Q22 A;  4FF1 A;  2VF1 A;  4KSA A;  4FZ4 A;  4FF2 A;  4QIC A;  2LFW A;  3VKG A;  2FP2 A;  4KSF A;  1Y0V A;  1PK0 A;  1K93 A;  3C3L A;  1SK6 A;  4F0X A;  3N0R A;  3CE2 A;  3C2P A;  2EBF X;  2EC5 A;  3C46 A;  4G97 A;  1XFU A;  2AO2 A;  2EBH X;  5GJW E;  4AKG A;  4AI6 A;  1XFX A;  4FF4 A;  4AKH A;  3Q23 A;  4AKI A;  1LVC A;  2GBB A;  1XFZ A;  3Q24 A;  1XFY A;  5GJV E;  3KML A;  1XFV A;  2AZE A;  2PO4 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2F6LA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations