2AZEA

Structure of the rb c-terminal domain bound to an e2f1-dp1 heterodimer
Total Genus 41
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
41
sequence length
149
structure length
149
Chain Sequence
FAQECQNLEVERQRRLERIKQKQSQLQELILQQIAFKNLVQRNRHAEQQASRPPPPNSVIHLPFIIVNTSKKTVIDCSISNDKFEYLFNFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKMARSLVPKALEPYVTEMAQGTVGGVF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the Rb C-terminal domain bound to E2F1-DP1: a mechanism for phosphorylation-induced E2F release.
pubmed doi rcsb
molecule tags Cell cycle, transcription
source organism Homo sapiens
molecule keywords Transcription factor Dp-1
total genus 41
structure length 149
sequence length 149
ec nomenclature
pdb deposition date 2005-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08781 DP Transcription factor DP
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.80 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 2azeA01
2AZEA
chains in the Genus database with same CATH superfamily
3BNJA 2E0AA 3MDEA 4H85A 1QDBA 5B6BA 4FF3A 3SCEA 2IX6A 4JEKA 4FF4A 1T9GA 1OAHA 3UBRA 1SK6A 3Q0AA 2YYIA 4L3XA 5B5WA 4W9UA 2CJ4A 1PI1A 1UDYA 1Y8NA 2EBAA 3GM6A 1SIQA 3HWCA 4FZ4A 3R7KA 3SXQA 3C3LA 4MP2A 3SF6A 1Y0VA 3MMOA 4FF2A 3OWAA 1GU6A 2UXWA 2OR0A 4G5EA 3C46A 3NF4A 4L38A 4NXLA 2EBFX 3X29A 1EGDA 1XFWA 4F0XA 1WS9A 5K3JA 1XG2B 4AKHA 4U83A 1PK0A 1RP3A 5B5VA 4MP7A 2JBTA 5BRKA 3D6BA 1K93A 2EBHX 3D1IA 2BU5A 3Q22A 4L3YA 1EGEA 3VKHA 3P4TA 2YYJA 2ZKJA 1R3BA 2EC5A 3AFEA 4P13A 4E02A 2CJ6A 2JBSA 2LFWA 2VIGA 2ZAFA 4ZXVA 3UU9A 3SWOA 2YYMA 4AKIA 1SIRA 3FCJA 3FO3A 4Q5BA 3C2PA 2WBIA 2REHA 3D9EA 4J1VA 1XFZA 3GNCA 3TTBA 4Q0TA 1XFUA 2CX9A 2FONA 2BU2A 3Q24A 1Y8PA 2R03A 3TZ4A 1LVCA 2R0MA 1R2JA 2XS1A 2BTZA 2XS8A 3KMLA 2Q8GA 4HR3A 3X0YA 2E81A 4Q5CA 2BU7A 4ZYJA 2ZDXA 2VR0A 5M4MA 2R05A 1XFXA 4E01A 2VF1A 1X90A 2YYLA 4HKRA 4RM7A 1JM6A 5K3HA 2Q8FA 3MDDA 2RF7A 3N0RA 2D29A 4E00A 2RDZA 3CRLA 4DOYA 1GJVA 2CJ7A 1FS9A 2OEXA 3TZ2A 3CRKA 4AI6A 3MPIA 2QR4A 2R02A 1RX0A 2Z1QA 3BNGA 2C12A 3D9FA 3L1TA 1XFVA 4H7QA 2CJ5A 4L3ZA 3Q23A 3D9GA 4KSFA 4MPCA 4JIOA 3TZ5A 3OWMA 3D2RA 2PNRA 4OO2A 2DDHA 4Q17A 3MPJA 1S26A 4LQSB 1EGCA 4KSAA 2JBRA 4QICA 1K90A 3MXLA 4AKGA 3B96A 5M4PA 1BUCA 2JIFA 4WJYA 2Q8HA 1Y8OA 3LG1A 3TORA 2FP2A 2DVLA 1U8VA 4IRNA 4IV6A 5J71A 3CE2A 4V26A 2FP1A 4JIZA 4HKSA 1GKZA 1K8TA 2J7AA 2ZDYA 5M4NA 1SC5A 2OJQA 3GQTA 4KCFA 2BU6A 2YGWA 1UKWA 4O5MA 3TZ0A 3D9DA 1RJ1A 4L1FA 3X0XA 3AFFA 5K3IA 2CJ8A 1IS2A 1W07A 2HJNA 3F29A 5GJWE 1RJ4A 4XVXA 5K3GA 2GBBA 2ZO5A 4MPEA 2A1TA 2OEVA 2IX5A 3OIBA 2Q8IA 2F6LA 3RKHA 1XFYA 4X28A 2PO4A 3PFDA 5BRMA 3BNFA 3BNHA 2C0UA 1IVHA 2XQRB 5J6AA 5GJVE 3S7WA 5M4KA 2RFQA 4P79A 4FF1A 1JQIA 2AZEA 2BU8A 3II9A 2YYKA 3LGQA 2AO2A 3EOMA 4H81A 3EONA 3VKGA 2PG0A 4MPNA 1X91A 3MKHA 2R0NA 4KTOA 3M9VA 4M9AA 1GKXA 1X8ZA 2E80A 2YYGA 2OT4A 1FS7A 4G97A 4Q1OA 4X28C 4Q4UA 4KS9A 3VADA 1FS8A 4DZYA 4LQQB 4V25A 4N5FA
chains in the Genus database with same CATH topology
4AKIA 4AI6A 4FF3A 4FF4A 2QR4A 5GJWE 3C2PA 1XFVA 1SK6A 2GBBA 3Q0AA 3Q23A 4KSFA 1XFZA 4FF1A 4FZ4A 3C3LA 1XFUA 2F6LA 1XFYA 3Q24A 2PO4A 1S26A 1Y0VA 4FF2A 4KSAA 4QICA 1LVCA 1K90A 5GJVE 3KMLA 3C46A 4AKGA 4P79A 2EBFX 2AZEA 3X29A 1XFWA 4F0XA 2AO2A 4AKHA 2FP2A 3CE2A 3VKGA 1XFXA 1PK0A 1RP3A 2FP1A 2VF1A 4HKRA 4HKSA 1K8TA 1K93A 1SC5A 2EBHX 3Q22A 2YGWA 3VKHA 3N0RA 4G97A 4KS9A 2EC5A 2LFWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AZE A; 
#chains in the Genus database with same CATH topology
 3BNJ A;  2E0A A;  3MDE A;  4H85 A;  1QDB A;  5B6B A;  4FF3 A;  3SCE A;  2IX6 A;  4JEK A;  4FF4 A;  1T9G A;  1OAH A;  3UBR A;  1SK6 A;  3Q0A A;  2YYI A;  4L3X A;  5B5W A;  4W9U A;  2CJ4 A;  1PI1 A;  1UDY A;  1Y8N A;  2EBA A;  3GM6 A;  1SIQ A;  3HWC A;  4FZ4 A;  3R7K A;  3SXQ A;  3C3L A;  4MP2 A;  3SF6 A;  1Y0V A;  3MMO A;  4FF2 A;  3OWA A;  1GU6 A;  2UXW A;  2OR0 A;  4G5E A;  3C46 A;  3NF4 A;  4L38 A;  4NXL A;  2EBF X;  3X29 A;  1EGD A;  1XFW A;  4F0X A;  1WS9 A;  5K3J A;  1XG2 B;  4AKH A;  4U83 A;  1PK0 A;  1RP3 A;  5B5V A;  4MP7 A;  2JBT A;  5BRK A;  3D6B A;  1K93 A;  2EBH X;  3D1I A;  2BU5 A;  3Q22 A;  4L3Y A;  1EGE A;  3VKH A;  3P4T A;  2YYJ A;  2ZKJ A;  1R3B A;  2EC5 A;  3AFE A;  4P13 A;  4E02 A;  2CJ6 A;  2JBS A;  2LFW A;  2VIG A;  2ZAF A;  4ZXV A;  3UU9 A;  3SWO A;  2YYM A;  4AKI A;  1SIR A;  3FCJ A;  3FO3 A;  4Q5B A;  3C2P A;  2WBI A;  2REH A;  3D9E A;  4J1V A;  1XFZ A;  3GNC A;  3TTB A;  4Q0T A;  1XFU A;  2CX9 A;  2FON A;  2BU2 A;  3Q24 A;  1Y8P A;  2R03 A;  3TZ4 A;  1LVC A;  2R0M A;  1R2J A;  2XS1 A;  2BTZ A;  2XS8 A;  3KML A;  2Q8G A;  4HR3 A;  3X0Y A;  2E81 A;  4Q5C A;  2BU7 A;  4ZYJ A;  2ZDX A;  2VR0 A;  5M4M A;  2R05 A;  1XFX A;  4E01 A;  2VF1 A;  1X90 A;  2YYL A;  4HKR A;  4RM7 A;  1JM6 A;  5K3H A;  2Q8F A;  3MDD A;  2RF7 A;  3N0R A;  2D29 A;  4E00 A;  2RDZ A;  3CRL A;  4DOY A;  1GJV A;  2CJ7 A;  1FS9 A;  2OEX A;  3TZ2 A;  3CRK A;  4AI6 A;  3MPI A;  2QR4 A;  2R02 A;  1RX0 A;  2Z1Q A;  3BNG A;  2C12 A;  3D9F A;  3L1T A;  1XFV A;  4H7Q A;  2CJ5 A;  4L3Z A;  3Q23 A;  3D9G A;  4KSF A;  4MPC A;  4JIO A;  3TZ5 A;  3OWM A;  3D2R A;  2PNR A;  4OO2 A;  2DDH A;  4Q17 A;  3MPJ A;  1S26 A;  4LQS B;  1EGC A;  4KSA A;  2JBR A;  4QIC A;  1K90 A;  3MXL A;  4AKG A;  3B96 A;  5M4P A;  1BUC A;  2JIF A;  4WJY A;  2Q8H A;  1Y8O A;  3LG1 A;  3TOR A;  2FP2 A;  2DVL A;  1U8V A;  4IRN A;  4IV6 A;  5J71 A;  3CE2 A;  4V26 A;  2FP1 A;  4JIZ A;  4HKS A;  1GKZ A;  1K8T A;  2J7A A;  2ZDY A;  5M4N A;  1SC5 A;  2OJQ A;  3GQT A;  4KCF A;  2BU6 A;  2YGW A;  1UKW A;  4O5M A;  3TZ0 A;  3D9D A;  1RJ1 A;  4L1F A;  3X0X A;  3AFF A;  5K3I A;  2CJ8 A;  1IS2 A;  1W07 A;  2HJN A;  3F29 A;  5GJW E;  1RJ4 A;  4XVX A;  5K3G A;  2GBB A;  2ZO5 A;  4MPE A;  2A1T A;  2OEV A;  2IX5 A;  3OIB A;  2Q8I A;  2F6L A;  3RKH A;  1XFY A;  4X28 A;  2PO4 A;  3PFD A;  5BRM A;  3BNF A;  3BNH A;  2C0U A;  1IVH A;  2XQR B;  5J6A A;  5GJV E;  3S7W A;  5M4K A;  2RFQ A;  4P79 A;  4FF1 A;  1JQI A;  2AZE A;  2BU8 A;  3II9 A;  2YYK A;  3LGQ A;  2AO2 A;  3EOM A;  4H81 A;  3EON A;  3VKG A;  2PG0 A;  4MPN A;  1X91 A;  3MKH A;  2R0N A;  4KTO A;  3M9V A;  4M9A A;  1GKX A;  1X8Z A;  2E80 A;  2YYG A;  2OT4 A;  1FS7 A;  4G97 A;  4Q1O A;  4X28 C;  4Q4U A;  4KS9 A;  3VAD A;  1FS8 A;  4DZY A;  4LQQ B;  4V25 A;  4N5F A; 
#chains in the Genus database with same CATH homology
 4AKI A;  4AI6 A;  4FF3 A;  4FF4 A;  2QR4 A;  5GJW E;  3C2P A;  1XFV A;  1SK6 A;  2GBB A;  3Q0A A;  3Q23 A;  4KSF A;  1XFZ A;  4FF1 A;  4FZ4 A;  3C3L A;  1XFU A;  2F6L A;  1XFY A;  3Q24 A;  2PO4 A;  1S26 A;  1Y0V A;  4FF2 A;  4KSA A;  4QIC A;  1LVC A;  1K90 A;  5GJV E;  3KML A;  3C46 A;  4AKG A;  4P79 A;  2EBF X;  2AZE A;  3X29 A;  1XFW A;  4F0X A;  2AO2 A;  4AKH A;  2FP2 A;  3CE2 A;  3VKG A;  1XFX A;  1PK0 A;  1RP3 A;  2FP1 A;  2VF1 A;  4HKR A;  4HKS A;  1K8T A;  1K93 A;  1SC5 A;  2EBH X;  3Q22 A;  2YGW A;  3VKH A;  3N0R A;  4G97 A;  4KS9 A;  2EC5 A;  2LFW A; 
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similar chains in the Genus database (?% sequence similarity)
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