4HKRA

Calcium release-activated calcium (crac) channel orai
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
191
structure length
165
Chain Sequence
TYLSWRKLQLSRAKLKASSKTSALLSGFAMVAMVEVQMLIAFAICTTLLVAVHMLALMISTCILPNPHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSRRAAWSATVVLIPVMIIFMAFAIHFYRSLVSHKYEVTVSGIRELEMLKEQMEQDHLEHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transport protein
source organism Drosophila melanogaster
publication title Crystal structure of the calcium release-activated calcium channel Orai.
pubmed doi rcsb
molecule keywords Calcium release-activated calcium channel protein 1
total genus 69
structure length 165
sequence length 191
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07856 Orai-1 Mediator of CRAC channel activity
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.140 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 4hkrA00
4HKSA 4HKRA
chains in the Genus database with same CATH superfamily
2RFQA 3SCEA 1Y8PA 4QICA 4HKRA 1X91A 3D2RA 2EC5A 3GQTA 3LG1A 4N5FA 4Q5BA 3TZ4A 5K3GA 3CRLA 3MKHA 1BUCA 2ZO5A 3R7KA 3C2PA 2EBHX 1SC5A 3S7WA 3HWCA 3EOMA 1SK6A 3CE2A 4J1VA 4KCFA 4DZYA 1RX0A 2FP2A 2XS8A 4FZ4A 3AFEA 4L3YA 4WJYA 2Q8IA 3MPJA 2JBTA 5GJWE 2C12A 2JIFA 2CJ7A 5GJVE 4MPNA 2PNRA 4JIZA 2DDHA 2J7AA 3X29A 4FF2A 3Q23A 4MP7A 3II9A 4DOYA 1EGDA 2FONA 3NF4A 4P13A 4G5EA 3SF6A 4W9UA 4X28C 2HJNA 4HKSA 2BU5A 2VF1A 2PG0A 2IX5A 4IV6A 3VKGA 4P79A 1GU6A 2LFWA 3C3LA 1GJVA 2OEXA 2R0MA 3MPIA 4H81A 4OO2A 5K3JA 2Q8HA 5BRKA 1IS2A 3PFDA 3C46A 2AO2A 2PO4A 3N0RA 1XFWA 2BU6A 4MP2A 1XFVA 2UXWA 2OEVA 2E81A 2JBSA 4Q5CA 4FF3A 5M4NA 1OAHA 1IVHA 3D9EA 4MPCA 2YYGA 4LQSB 2AZEA 2R03A 1K8TA 2YYJA 1JM6A 1XFZA 3D9GA 2BU8A 4HR3A 2DVLA 3UU9A 1K93A 1EGCA 3BNHA 4XVXA 1GKZA 2CJ6A 3X0XA 4E01A 1R3BA 1X90A 1UDYA 2OR0A 3OIBA 3OWAA 5M4PA 4AKIA 2F6LA 1Y8OA 1XFXA 3TORA 1XG2B 2JBRA 3TTBA 3D9DA 4E02A 2Q8FA 2BU2A 3SXQA 5B6BA 5J6AA 4H85A 3CRKA 4KSAA 3SWOA 3M9VA 3MDEA 4G97A 1RJ4A 3BNJA 1GKXA 3EONA 4RM7A 2OT4A 4LQQB 4V26A 2CX9A 2YGWA 2RDZA 1FS7A 1X8ZA 4Q4UA 2WBIA 1XFYA 2D29A 5B5WA 1Y0VA 2QR4A 2CJ5A 2Z1QA 2REHA 4U83A 3VADA 5M4MA 2CJ4A 4ZYJA 2YYLA 2YYKA 3VKHA 4M9AA 3D6BA 1QDBA 3TZ2A 2ZDXA 2RF7A 1WS9A 3BNGA 1JQIA 4KTOA 4X28A 3L1TA 3B96A 3P4TA 2CJ8A 4Q0TA 4MPEA 3TZ0A 5K3HA 1S26A 4V25A 2E0AA 2VIGA 1SIQA 2IX6A 3MMOA 4E00A 3Q24A 4O5MA 3Q0AA 3LGQA 1FS9A 1SIRA 1K90A 1Y8NA 4KSFA 1LVCA 4KS9A 4ZXVA 1FS8A 2YYIA 5BRMA 3UBRA 3X0YA 4Q17A 5K3IA 4AKHA 2R02A 3BNFA 2BTZA 3AFFA 3TZ5A 2BU7A 3D1IA 5M4KA 3OWMA 1R2JA 1RJ1A 4L3ZA 1W07A 2EBAA 2ZDYA 2YYMA 3KMLA 1RP3A 4NXLA 2R05A 2R0NA 4IRNA 4L38A 2E80A 4L3XA 2VR0A 4F0XA 1PK0A 4H7QA 2A1TA 1T9GA 3MXLA 2FP1A 2GBBA 4AKGA 4JEKA 2OJQA 4JIOA 1PI1A 5B5VA 3FCJA 4AI6A 3RKHA 4FF1A 3FO3A 4FF4A 1UKWA 2Q8GA 2EBFX 2XS1A 5J71A 2XQRB 3F29A 3GM6A 1XFUA 2ZAFA 3GNCA 1U8VA 2C0UA 3Q22A 2ZKJA 3D9FA 1EGEA 4L1FA 3MDDA 4Q1OA
chains in the Genus database with same CATH topology
2LFWA 3C3LA 4FF1A 4QICA 4KSAA 4HKRA 4G97A 4AKHA 2EC5A 3VKHA 3C46A 2AO2A 2PO4A 3C2PA 2YGWA 3N0RA 1XFWA 2EBHX 1RP3A 1SC5A 3KMLA 1XFYA 1XFVA 1Y0VA 2QR4A 1SK6A 3CE2A 4F0XA 2FP2A 1PK0A 4FZ4A 4FF3A 2FP1A 2GBBA 5GJWE 4AKGA 5GJVE 2AZEA 1K8TA 1XFZA 4AI6A 3VKGA 1K93A 3X29A 1S26A 3Q24A 3Q23A 4FF2A 4FF4A 2EBFX 4AKIA 3Q0AA 1K90A 1XFUA 4KSFA 2F6LA 3Q22A 1LVCA 4HKSA 2VF1A 4KS9A 1XFXA 4P79A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HKS A;  4HKR A; 
#chains in the Genus database with same CATH topology
 2RFQ A;  3SCE A;  1Y8P A;  4QIC A;  4HKR A;  1X91 A;  3D2R A;  2EC5 A;  3GQT A;  3LG1 A;  4N5F A;  4Q5B A;  3TZ4 A;  5K3G A;  3CRL A;  3MKH A;  1BUC A;  2ZO5 A;  3R7K A;  3C2P A;  2EBH X;  1SC5 A;  3S7W A;  3HWC A;  3EOM A;  1SK6 A;  3CE2 A;  4J1V A;  4KCF A;  4DZY A;  1RX0 A;  2FP2 A;  2XS8 A;  4FZ4 A;  3AFE A;  4L3Y A;  4WJY A;  2Q8I A;  3MPJ A;  2JBT A;  5GJW E;  2C12 A;  2JIF A;  2CJ7 A;  5GJV E;  4MPN A;  2PNR A;  4JIZ A;  2DDH A;  2J7A A;  3X29 A;  4FF2 A;  3Q23 A;  4MP7 A;  3II9 A;  4DOY A;  1EGD A;  2FON A;  3NF4 A;  4P13 A;  4G5E A;  3SF6 A;  4W9U A;  4X28 C;  2HJN A;  4HKS A;  2BU5 A;  2VF1 A;  2PG0 A;  2IX5 A;  4IV6 A;  3VKG A;  4P79 A;  1GU6 A;  2LFW A;  3C3L A;  1GJV A;  2OEX A;  2R0M A;  3MPI A;  4H81 A;  4OO2 A;  5K3J A;  2Q8H A;  5BRK A;  1IS2 A;  3PFD A;  3C46 A;  2AO2 A;  2PO4 A;  3N0R A;  1XFW A;  2BU6 A;  4MP2 A;  1XFV A;  2UXW A;  2OEV A;  2E81 A;  2JBS A;  4Q5C A;  4FF3 A;  5M4N A;  1OAH A;  1IVH A;  3D9E A;  4MPC A;  2YYG A;  4LQS B;  2AZE A;  2R03 A;  1K8T A;  2YYJ A;  1JM6 A;  1XFZ A;  3D9G A;  2BU8 A;  4HR3 A;  2DVL A;  3UU9 A;  1K93 A;  1EGC A;  3BNH A;  4XVX A;  1GKZ A;  2CJ6 A;  3X0X A;  4E01 A;  1R3B A;  1X90 A;  1UDY A;  2OR0 A;  3OIB A;  3OWA A;  5M4P A;  4AKI A;  2F6L A;  1Y8O A;  1XFX A;  3TOR A;  1XG2 B;  2JBR A;  3TTB A;  3D9D A;  4E02 A;  2Q8F A;  2BU2 A;  3SXQ A;  5B6B A;  5J6A A;  4H85 A;  3CRK A;  4KSA A;  3SWO A;  3M9V A;  3MDE A;  4G97 A;  1RJ4 A;  3BNJ A;  1GKX A;  3EON A;  4RM7 A;  2OT4 A;  4LQQ B;  4V26 A;  2CX9 A;  2YGW A;  2RDZ A;  1FS7 A;  1X8Z A;  4Q4U A;  2WBI A;  1XFY A;  2D29 A;  5B5W A;  1Y0V A;  2QR4 A;  2CJ5 A;  2Z1Q A;  2REH A;  4U83 A;  3VAD A;  5M4M A;  2CJ4 A;  4ZYJ A;  2YYL A;  2YYK A;  3VKH A;  4M9A A;  3D6B A;  1QDB A;  3TZ2 A;  2ZDX A;  2RF7 A;  1WS9 A;  3BNG A;  1JQI A;  4KTO A;  4X28 A;  3L1T A;  3B96 A;  3P4T A;  2CJ8 A;  4Q0T A;  4MPE A;  3TZ0 A;  5K3H A;  1S26 A;  4V25 A;  2E0A A;  2VIG A;  1SIQ A;  2IX6 A;  3MMO A;  4E00 A;  3Q24 A;  4O5M A;  3Q0A A;  3LGQ A;  1FS9 A;  1SIR A;  1K90 A;  1Y8N A;  4KSF A;  1LVC A;  4KS9 A;  4ZXV A;  1FS8 A;  2YYI A;  5BRM A;  3UBR A;  3X0Y A;  4Q17 A;  5K3I A;  4AKH A;  2R02 A;  3BNF A;  2BTZ A;  3AFF A;  3TZ5 A;  2BU7 A;  3D1I A;  5M4K A;  3OWM A;  1R2J A;  1RJ1 A;  4L3Z A;  1W07 A;  2EBA A;  2ZDY A;  2YYM A;  3KML A;  1RP3 A;  4NXL A;  2R05 A;  2R0N A;  4IRN A;  4L38 A;  2E80 A;  4L3X A;  2VR0 A;  4F0X A;  1PK0 A;  4H7Q A;  2A1T A;  1T9G A;  3MXL A;  2FP1 A;  2GBB A;  4AKG A;  4JEK A;  2OJQ A;  4JIO A;  1PI1 A;  5B5V A;  3FCJ A;  4AI6 A;  3RKH A;  4FF1 A;  3FO3 A;  4FF4 A;  1UKW A;  2Q8G A;  2EBF X;  2XS1 A;  5J71 A;  2XQR B;  3F29 A;  3GM6 A;  1XFU A;  2ZAF A;  3GNC A;  1U8V A;  2C0U A;  3Q22 A;  2ZKJ A;  3D9F A;  1EGE A;  4L1F A;  3MDD A;  4Q1O A; 
#chains in the Genus database with same CATH homology
 2LFW A;  3C3L A;  4FF1 A;  4QIC A;  4KSA A;  4HKR A;  4G97 A;  4AKH A;  2EC5 A;  3VKH A;  3C46 A;  2AO2 A;  2PO4 A;  3C2P A;  2YGW A;  3N0R A;  1XFW A;  2EBH X;  1RP3 A;  1SC5 A;  3KML A;  1XFY A;  1XFV A;  1Y0V A;  2QR4 A;  1SK6 A;  3CE2 A;  4F0X A;  2FP2 A;  1PK0 A;  4FZ4 A;  4FF3 A;  2FP1 A;  2GBB A;  5GJW E;  4AKG A;  5GJV E;  2AZE A;  1K8T A;  1XFZ A;  4AI6 A;  3VKG A;  1K93 A;  3X29 A;  1S26 A;  3Q24 A;  3Q23 A;  4FF2 A;  4FF4 A;  2EBF X;  4AKI A;  3Q0A A;  1K90 A;  1XFU A;  4KSF A;  2F6L A;  3Q22 A;  1LVC A;  4HKS A;  2VF1 A;  4KS9 A;  1XFX A;  4P79 A; 
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