4HKRA

Calcium release-activated calcium (crac) channel orai
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
191
structure length
165
Chain Sequence
TYLSWRKLQLSRAKLKASSKTSALLSGFAMVAMVEVQMLIAFAICTTLLVAVHMLALMISTCILPNPHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSRRAAWSATVVLIPVMIIFMAFAIHFYRSLVSHKYEVTVSGIRELEMLKEQMEQDHLEHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the calcium release-activated calcium channel Orai.
pubmed doi rcsb
molecule tags Transport protein
source organism Drosophila melanogaster
molecule keywords Calcium release-activated calcium channel protein 1
total genus 69
structure length 165
sequence length 191
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07856 Orai-1 Mediator of CRAC channel activity
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.140 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 4hkrA00
4HKSA 4HKRA
chains in the Genus database with same CATH superfamily
3OIBA 3BNHA 3OWAA 1X8ZA 2YYIA 5K3JA 2Q8GA 4V25A 3SCEA 4F0XA 3Q23A 3MDDA 4W9UA 1R3BA 3AFFA 2CJ6A 2A1TA 2CJ5A 2YYGA 2BU5A 1SK6A 3II9A 3FCJA 4JIZA 1Y8PA 2RFQA 3BNJA 4L3XA 2R0NA 2D29A 2VF1A 2EBAA 1SIRA 2QR4A 1R2JA 3MPJA 4DZYA 2XS1A 5M4PA 2DDHA 2YYJA 4E00A 1QDBA 2EBFX 2ZAFA 2VIGA 2E80A 3HWCA 3C46A 3UU9A 2BU2A 3F29A 4QICA 4AKGA 1RJ1A 3LGQA 5K3HA 4AI6A 2YGWA 3D9EA 2E0AA 5K3GA 1XFVA 2BU7A 4IRNA 5M4NA 2Q8IA 1K8TA 1GKZA 4H7QA 3X0XA 4MPEA 2Z1QA 5B5VA 3GQTA 5GJWE 1RJ4A 2BTZA 4P79A 3TZ5A 3RKHA 1EGCA 1LVCA 4AKIA 1Y8OA 1SIQA 2VR0A 3LG1A 3MKHA 4U83A 3PFDA 2PG0A 2C0UA 1IS2A 1X90A 1K93A 2F6LA 2R02A 3CE2A 4Q5BA 4H81A 3NF4A 3MPIA 3S7WA 4L1FA 1U8VA 2FONA 2R03A 1GU6A 2IX5A 2R05A 3EOMA 4NXLA 3D9FA 4O5MA 1K90A 1BUCA 4KSFA 4LQQB 2Q8FA 4FF3A 4FF4A 5BRKA 3Q24A 4H85A 4HR3A 2XS8A 4X28A 1Y0VA 3MMOA 2JBRA 1PI1A 2FP2A 4G5EA 2AZEA 4FF2A 2FP1A 4HKRA 1OAHA 3Q22A 4E01A 2C12A 2R0MA 4LQSB 3SXQA 4DOYA 1RX0A 3BNFA 3VKGA 1XFWA 3TTBA 3FO3A 3EONA 5B5WA 4Q0TA 4ZYJA 2RDZA 5M4MA 3MDEA 1FS8A 4J1VA 4Q1OA 1SC5A 4M9AA 2JBSA 3OWMA 2OR0A 4Q17A 2CJ7A 3X29A 1XG2B 2OJQA 4MP2A 1UKWA 3VADA 3CRLA 1PK0A 1GKXA 2EC5A 3BNGA 2CJ8A 4N5FA 3D9DA 5GJVE 3UBRA 3D1IA 1JQIA 4FF1A 3AFEA 2OT4A 2REHA 1UDYA 1JM6A 1XFXA 1FS9A 2IX6A 2WBIA 2YYKA 2ZDYA 4HKSA 2XQRB 4KTOA 3TZ4A 2OEXA 1W07A 1Y8NA 2ZO5A 1EGDA 5J71A 4E02A 3B96A 1GJVA 2HJNA 3TZ2A 4MP7A 2CJ4A 4P13A 2ZDXA 2EBHX 4Q4UA 4L3YA 4AKHA 3VKHA 3MXLA 4MPNA 1XFUA 2Q8HA 5M4KA 4KS9A 1RP3A 3KMLA 3D6BA 4MPCA 4FZ4A 4KSAA 2DVLA 3L1TA 2JBTA 4XVXA 3D9GA 3R7KA 4G97A 2RF7A 4RM7A 3C3LA 3D2RA 1T9GA 3SF6A 2GBBA 3TORA 4X28C 4KCFA 3P4TA 1EGEA 4V26A 2YYMA 3GM6A 4ZXVA 1XFZA 4L3ZA 2YYLA 5B6BA 4WJYA 3C2PA 3SWOA 1X91A 1FS7A 2BU6A 2AO2A 3M9VA 4IV6A 3GNCA 4Q5CA 5BRMA 3X0YA 2PNRA 2JIFA 2LFWA 2OEVA 4L38A 4OO2A 1S26A 5J6AA 2ZKJA 4JIOA 3TZ0A 2CX9A 1IVHA 1XFYA 5K3IA 2BU8A 4JEKA 3N0RA 2PO4A 2J7AA 1WS9A 2E81A 2UXWA 3Q0AA 3CRKA
chains in the Genus database with same CATH topology
4KS9A 1RP3A 4P79A 1LVCA 3KMLA 4F0XA 3Q23A 4AKIA 1SC5A 4FZ4A 4KSAA 3X29A 3CE2A 4G97A 1K93A 2F6LA 1PK0A 1SK6A 2EC5A 3C3LA 5GJVE 2GBBA 4FF4A 1K90A 4KSFA 4FF1A 4FF3A 1XFXA 2VF1A 2QR4A 4HKSA 1XFZA 2EBFX 3Q24A 3C2PA 3C46A 2AO2A 4QICA 1Y0VA 4AKGA 2LFWA 2FP2A 4AI6A 1S26A 2AZEA 2YGWA 2FP1A 4FF2A 1XFVA 4HKRA 3Q22A 1K8TA 1XFYA 2EBHX 4AKHA 3N0RA 2PO4A 1XFWA 3VKHA 3VKGA 1XFUA 5GJWE 3Q0AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HKS A;  4HKR A; 
#chains in the Genus database with same CATH topology
 3OIB A;  3BNH A;  3OWA A;  1X8Z A;  2YYI A;  5K3J A;  2Q8G A;  4V25 A;  3SCE A;  4F0X A;  3Q23 A;  3MDD A;  4W9U A;  1R3B A;  3AFF A;  2CJ6 A;  2A1T A;  2CJ5 A;  2YYG A;  2BU5 A;  1SK6 A;  3II9 A;  3FCJ A;  4JIZ A;  1Y8P A;  2RFQ A;  3BNJ A;  4L3X A;  2R0N A;  2D29 A;  2VF1 A;  2EBA A;  1SIR A;  2QR4 A;  1R2J A;  3MPJ A;  4DZY A;  2XS1 A;  5M4P A;  2DDH A;  2YYJ A;  4E00 A;  1QDB A;  2EBF X;  2ZAF A;  2VIG A;  2E80 A;  3HWC A;  3C46 A;  3UU9 A;  2BU2 A;  3F29 A;  4QIC A;  4AKG A;  1RJ1 A;  3LGQ A;  5K3H A;  4AI6 A;  2YGW A;  3D9E A;  2E0A A;  5K3G A;  1XFV A;  2BU7 A;  4IRN A;  5M4N A;  2Q8I A;  1K8T A;  1GKZ A;  4H7Q A;  3X0X A;  4MPE A;  2Z1Q A;  5B5V A;  3GQT A;  5GJW E;  1RJ4 A;  2BTZ A;  4P79 A;  3TZ5 A;  3RKH A;  1EGC A;  1LVC A;  4AKI A;  1Y8O A;  1SIQ A;  2VR0 A;  3LG1 A;  3MKH A;  4U83 A;  3PFD A;  2PG0 A;  2C0U A;  1IS2 A;  1X90 A;  1K93 A;  2F6L A;  2R02 A;  3CE2 A;  4Q5B A;  4H81 A;  3NF4 A;  3MPI A;  3S7W A;  4L1F A;  1U8V A;  2FON A;  2R03 A;  1GU6 A;  2IX5 A;  2R05 A;  3EOM A;  4NXL A;  3D9F A;  4O5M A;  1K90 A;  1BUC A;  4KSF A;  4LQQ B;  2Q8F A;  4FF3 A;  4FF4 A;  5BRK A;  3Q24 A;  4H85 A;  4HR3 A;  2XS8 A;  4X28 A;  1Y0V A;  3MMO A;  2JBR A;  1PI1 A;  2FP2 A;  4G5E A;  2AZE A;  4FF2 A;  2FP1 A;  4HKR A;  1OAH A;  3Q22 A;  4E01 A;  2C12 A;  2R0M A;  4LQS B;  3SXQ A;  4DOY A;  1RX0 A;  3BNF A;  3VKG A;  1XFW A;  3TTB A;  3FO3 A;  3EON A;  5B5W A;  4Q0T A;  4ZYJ A;  2RDZ A;  5M4M A;  3MDE A;  1FS8 A;  4J1V A;  4Q1O A;  1SC5 A;  4M9A A;  2JBS A;  3OWM A;  2OR0 A;  4Q17 A;  2CJ7 A;  3X29 A;  1XG2 B;  2OJQ A;  4MP2 A;  1UKW A;  3VAD A;  3CRL A;  1PK0 A;  1GKX A;  2EC5 A;  3BNG A;  2CJ8 A;  4N5F A;  3D9D A;  5GJV E;  3UBR A;  3D1I A;  1JQI A;  4FF1 A;  3AFE A;  2OT4 A;  2REH A;  1UDY A;  1JM6 A;  1XFX A;  1FS9 A;  2IX6 A;  2WBI A;  2YYK A;  2ZDY A;  4HKS A;  2XQR B;  4KTO A;  3TZ4 A;  2OEX A;  1W07 A;  1Y8N A;  2ZO5 A;  1EGD A;  5J71 A;  4E02 A;  3B96 A;  1GJV A;  2HJN A;  3TZ2 A;  4MP7 A;  2CJ4 A;  4P13 A;  2ZDX A;  2EBH X;  4Q4U A;  4L3Y A;  4AKH A;  3VKH A;  3MXL A;  4MPN A;  1XFU A;  2Q8H A;  5M4K A;  4KS9 A;  1RP3 A;  3KML A;  3D6B A;  4MPC A;  4FZ4 A;  4KSA A;  2DVL A;  3L1T A;  2JBT A;  4XVX A;  3D9G A;  3R7K A;  4G97 A;  2RF7 A;  4RM7 A;  3C3L A;  3D2R A;  1T9G A;  3SF6 A;  2GBB A;  3TOR A;  4X28 C;  4KCF A;  3P4T A;  1EGE A;  4V26 A;  2YYM A;  3GM6 A;  4ZXV A;  1XFZ A;  4L3Z A;  2YYL A;  5B6B A;  4WJY A;  3C2P A;  3SWO A;  1X91 A;  1FS7 A;  2BU6 A;  2AO2 A;  3M9V A;  4IV6 A;  3GNC A;  4Q5C A;  5BRM A;  3X0Y A;  2PNR A;  2JIF A;  2LFW A;  2OEV A;  4L38 A;  4OO2 A;  1S26 A;  5J6A A;  2ZKJ A;  4JIO A;  3TZ0 A;  2CX9 A;  1IVH A;  1XFY A;  5K3I A;  2BU8 A;  4JEK A;  3N0R A;  2PO4 A;  2J7A A;  1WS9 A;  2E81 A;  2UXW A;  3Q0A A;  3CRK A; 
#chains in the Genus database with same CATH homology
 4KS9 A;  1RP3 A;  4P79 A;  1LVC A;  3KML A;  4F0X A;  3Q23 A;  4AKI A;  1SC5 A;  4FZ4 A;  4KSA A;  3X29 A;  3CE2 A;  4G97 A;  1K93 A;  2F6L A;  1PK0 A;  1SK6 A;  2EC5 A;  3C3L A;  5GJV E;  2GBB A;  4FF4 A;  1K90 A;  4KSF A;  4FF1 A;  4FF3 A;  1XFX A;  2VF1 A;  2QR4 A;  4HKS A;  1XFZ A;  2EBF X;  3Q24 A;  3C2P A;  3C46 A;  2AO2 A;  4QIC A;  1Y0V A;  4AKG A;  2LFW A;  2FP2 A;  4AI6 A;  1S26 A;  2AZE A;  2YGW A;  2FP1 A;  4FF2 A;  1XFV A;  4HKR A;  3Q22 A;  1K8T A;  1XFY A;  2EBH X;  4AKH A;  3N0R A;  2PO4 A;  1XFW A;  3VKH A;  3VKG A;  1XFU A;  5GJW E;  3Q0A A; 
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