4HKR | Genus

Total Genus 69

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	69
sequence length	191
structure length	165
Chain Sequence	TYLSWRKLQLSRAKLKASSKTSALLSGFAMVAMVEVQMLIAFAICTTLLVAVHMLALMISTCILPNPHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSRRAAWSATVVLIPVMIIFMAFAIHFYRSLVSHKYEVTVSGIRELEMLKEQMEQDHLEHH

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transport protein
source organism	Drosophila melanogaster
publication title	Crystal structure of the calcium release-activated calcium channel Orai. pubmed doi rcsb
molecule keywords	Calcium release-activated calcium channel protein 1
total genus	69
structure length	165
sequence length	191
chains with identical sequence	B
ec nomenclature
pdb deposition date	2012-10-15

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF07856	Orai-1	Mediator of CRAC channel activity

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.140.140	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A; domain 3	Butyryl-CoA Dehydrogenase, subunit A; domain 3	4hkrA00

4HKSA 4HKRA
chains in the Genus database with same CATH superfamily

3D1IA 2BTZA 3SF6A 3MKHA 1R3BA 3D9EA 3OIBA 1K8TA 2J7AA 3X0YA 1EGDA 2GBBA 2HJNA 2CJ5A 3LGQA 3Q0AA 2YYIA 4LQSB 3C46A 2OR0A 5GJVE 1K90A 2PNRA 4MPNA 4JEKA 4MPEA 4ZXVA 3CE2A 3UU9A 2RDZA 2AO2A 2VR0A 2ZAFA 4WJYA 1OAHA 3GQTA 3OWAA 5M4KA 4L3YA 4Q0TA 1JM6A 1U8VA 4E01A 1IVHA 1XFVA 2PO4A 4IV6A 4W9UA 2YYKA 1QDBA 2Q8GA 2CJ4A 2R02A 4FZ4A 3C2PA 4E02A 2DVLA 2UXWA 3EONA 4HR3A 3N0RA 4G97A 3BNJA 1X8ZA 4QICA 2VIGA 1BUCA 1EGCA 2BU6A 3EOMA 5BRMA 2Q8HA 1RJ4A 5B6BA 4AI6A 3PFDA 1T9GA 2IX6A 1UDYA 3B96A 3BNFA 3MPJA 4LQQB 2OT4A 2Q8IA 2C12A 4KTOA 3SCEA 4AKHA 4L38A 1UKWA 5J6AA 3GM6A 4KCFA 3AFEA 2DDHA 1X91A 1XFUA 3TZ5A 1JQIA 2FONA 4HKRA 3VKHA 2EBAA 3P4TA 3Q22A 1S26A 5M4MA 2IX5A 3D9GA 1Y8NA 4Q5CA 3D6BA 5B5VA 2R03A 2CJ8A 2R0MA 3MMOA 4KSFA 4L3XA 4E00A 2YYMA 3SWOA 1Y8OA 2VF1A 1X90A 4AKIA 3VKGA 1SK6A 1SIQA 1XG2B 4DOYA 2EBFX 2OJQA 2E81A 5M4PA 3GNCA 2QR4A 3II9A 4L3ZA 4H81A 4DZYA 5B5WA 2BU7A 3F29A 2Z1QA 2YYJA 3HWCA 1K93A 1PK0A 1FS8A 5K3IA 4N5FA 3Q23A 3D9FA 2XS1A 3X0XA 4FF4A 2WBIA 1XFYA 4Q17A 2JIFA 2XS8A 2JBTA 1RJ1A 2ZKJA 4L1FA 3R7KA 1R2JA 5J71A 2ZDXA 2XQRB 4FF3A 2E80A 3FO3A 2FP2A 4Q4UA 2EBHX 2E0AA 3TORA 2JBSA 4F0XA 3CRLA 1PI1A 4JIOA 4KSAA 4OO2A 3TZ0A 4V26A 4JIZA 4X28A 4P13A 5M4NA 3FCJA 2PG0A 4FF2A 3RKHA 4KS9A 4MPCA 2OEXA 4U83A 4FF1A 3M9VA 1SIRA 2BU2A 3TTBA 3TZ2A 3X29A 3CRKA 3SXQA 1GKZA 2AZEA 2C0UA 4Q5BA 3D9DA 5BRKA 3NF4A 1XFXA 4V25A 2A1TA 2LFWA 2CX9A 3MXLA 5K3GA 4P79A 4AKGA 2YYGA 2FP1A 2R05A 1IS2A 4M9AA 3UBRA 2RF7A 3S7WA 4G5EA 3MDEA 2YGWA 4Q1OA 4IRNA 3BNGA 3MPIA 5K3JA 5GJWE 2ZO5A 4MP7A 1RX0A 2ZDYA 3Q24A 1LVCA 2YYLA 1GKXA 4NXLA 1GU6A 2RFQA 2CJ7A 1W07A 2D29A 2BU8A 3MDDA 1EGEA 2BU5A 3LG1A 4H7QA 2REHA 3KMLA 4HKSA 1XFZA 3TZ4A 3D2RA 4MP2A 3VADA 1WS9A 1XFWA 2CJ6A 2OEVA 3OWMA 1Y0VA 4H85A 4ZYJA 4J1VA 4XVXA 1GJVA 1Y8PA 2EC5A 2F6LA 3C3LA 1FS9A 3L1TA 3BNHA 4O5MA 4RM7A 4X28C 1SC5A 2JBRA 2R0NA 3AFFA 2Q8FA 5K3HA 1FS7A 1RP3A
chains in the Genus database with same CATH topology

4AKGA 2FP1A 4FF4A 1XFYA 1XFUA 1K8TA 3VKHA 4HKRA 3Q0AA 2GBBA 2YGWA 4FF3A 3Q22A 1S26A 3C46A 5GJVE 1K90A 5GJWE 2FP2A 2EBHX 3Q24A 4KSFA 3CE2A 1LVCA 4F0XA 2AO2A 4KSAA 4P79A 2VF1A 4HKSA 4AKIA 3VKGA 1SK6A 3KMLA 1XFZA 2EBFX 1XFWA 2PO4A 1XFVA 4FF2A 1Y0VA 2QR4A 4KS9A 4FF1A 4FZ4A 3C2PA 4QICA 2EC5A 2F6LA 3N0RA 4G97A 3C3LA 3X29A 2AZEA 1K93A 1PK0A 1SC5A 4AI6A 1XFXA 3Q23A 2LFWA 4AKHA 1RP3A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 4HKS A;  4HKR A; 
#chains in the Genus database with same CATH topology
 3D1I A;  2BTZ A;  3SF6 A;  3MKH A;  1R3B A;  3D9E A;  3OIB A;  1K8T A;  2J7A A;  3X0Y A;  1EGD A;  2GBB A;  2HJN A;  2CJ5 A;  3LGQ A;  3Q0A A;  2YYI A;  4LQS B;  3C46 A;  2OR0 A;  5GJV E;  1K90 A;  2PNR A;  4MPN A;  4JEK A;  4MPE A;  4ZXV A;  3CE2 A;  3UU9 A;  2RDZ A;  2AO2 A;  2VR0 A;  2ZAF A;  4WJY A;  1OAH A;  3GQT A;  3OWA A;  5M4K A;  4L3Y A;  4Q0T A;  1JM6 A;  1U8V A;  4E01 A;  1IVH A;  1XFV A;  2PO4 A;  4IV6 A;  4W9U A;  2YYK A;  1QDB A;  2Q8G A;  2CJ4 A;  2R02 A;  4FZ4 A;  3C2P A;  4E02 A;  2DVL A;  2UXW A;  3EON A;  4HR3 A;  3N0R A;  4G97 A;  3BNJ A;  1X8Z A;  4QIC A;  2VIG A;  1BUC A;  1EGC A;  2BU6 A;  3EOM A;  5BRM A;  2Q8H A;  1RJ4 A;  5B6B A;  4AI6 A;  3PFD A;  1T9G A;  2IX6 A;  1UDY A;  3B96 A;  3BNF A;  3MPJ A;  4LQQ B;  2OT4 A;  2Q8I A;  2C12 A;  4KTO A;  3SCE A;  4AKH A;  4L38 A;  1UKW A;  5J6A A;  3GM6 A;  4KCF A;  3AFE A;  2DDH A;  1X91 A;  1XFU A;  3TZ5 A;  1JQI A;  2FON A;  4HKR A;  3VKH A;  2EBA A;  3P4T A;  3Q22 A;  1S26 A;  5M4M A;  2IX5 A;  3D9G A;  1Y8N A;  4Q5C A;  3D6B A;  5B5V A;  2R03 A;  2CJ8 A;  2R0M A;  3MMO A;  4KSF A;  4L3X A;  4E00 A;  2YYM A;  3SWO A;  1Y8O A;  2VF1 A;  1X90 A;  4AKI A;  3VKG A;  1SK6 A;  1SIQ A;  1XG2 B;  4DOY A;  2EBF X;  2OJQ A;  2E81 A;  5M4P A;  3GNC A;  2QR4 A;  3II9 A;  4L3Z A;  4H81 A;  4DZY A;  5B5W A;  2BU7 A;  3F29 A;  2Z1Q A;  2YYJ A;  3HWC A;  1K93 A;  1PK0 A;  1FS8 A;  5K3I A;  4N5F A;  3Q23 A;  3D9F A;  2XS1 A;  3X0X A;  4FF4 A;  2WBI A;  1XFY A;  4Q17 A;  2JIF A;  2XS8 A;  2JBT A;  1RJ1 A;  2ZKJ A;  4L1F A;  3R7K A;  1R2J A;  5J71 A;  2ZDX A;  2XQR B;  4FF3 A;  2E80 A;  3FO3 A;  2FP2 A;  4Q4U A;  2EBH X;  2E0A A;  3TOR A;  2JBS A;  4F0X A;  3CRL A;  1PI1 A;  4JIO A;  4KSA A;  4OO2 A;  3TZ0 A;  4V26 A;  4JIZ A;  4X28 A;  4P13 A;  5M4N A;  3FCJ A;  2PG0 A;  4FF2 A;  3RKH A;  4KS9 A;  4MPC A;  2OEX A;  4U83 A;  4FF1 A;  3M9V A;  1SIR A;  2BU2 A;  3TTB A;  3TZ2 A;  3X29 A;  3CRK A;  3SXQ A;  1GKZ A;  2AZE A;  2C0U A;  4Q5B A;  3D9D A;  5BRK A;  3NF4 A;  1XFX A;  4V25 A;  2A1T A;  2LFW A;  2CX9 A;  3MXL A;  5K3G A;  4P79 A;  4AKG A;  2YYG A;  2FP1 A;  2R05 A;  1IS2 A;  4M9A A;  3UBR A;  2RF7 A;  3S7W A;  4G5E A;  3MDE A;  2YGW A;  4Q1O A;  4IRN A;  3BNG A;  3MPI A;  5K3J A;  5GJW E;  2ZO5 A;  4MP7 A;  1RX0 A;  2ZDY A;  3Q24 A;  1LVC A;  2YYL A;  1GKX A;  4NXL A;  1GU6 A;  2RFQ A;  2CJ7 A;  1W07 A;  2D29 A;  2BU8 A;  3MDD A;  1EGE A;  2BU5 A;  3LG1 A;  4H7Q A;  2REH A;  3KML A;  4HKS A;  1XFZ A;  3TZ4 A;  3D2R A;  4MP2 A;  3VAD A;  1WS9 A;  1XFW A;  2CJ6 A;  2OEV A;  3OWM A;  1Y0V A;  4H85 A;  4ZYJ A;  4J1V A;  4XVX A;  1GJV A;  1Y8P A;  2EC5 A;  2F6L A;  3C3L A;  1FS9 A;  3L1T A;  3BNH A;  4O5M A;  4RM7 A;  4X28 C;  1SC5 A;  2JBR A;  2R0N A;  3AFF A;  2Q8F A;  5K3H A;  1FS7 A;  1RP3 A; 
#chains in the Genus database with same CATH homology
 4AKG A;  2FP1 A;  4FF4 A;  1XFY A;  1XFU A;  1K8T A;  3VKH A;  4HKR A;  3Q0A A;  2GBB A;  2YGW A;  4FF3 A;  3Q22 A;  1S26 A;  3C46 A;  5GJV E;  1K90 A;  5GJW E;  2FP2 A;  2EBH X;  3Q24 A;  4KSF A;  3CE2 A;  1LVC A;  4F0X A;  2AO2 A;  4KSA A;  4P79 A;  2VF1 A;  4HKS A;  4AKI A;  3VKG A;  1SK6 A;  3KML A;  1XFZ A;  2EBF X;  1XFW A;  2PO4 A;  1XFV A;  4FF2 A;  1Y0V A;  2QR4 A;  4KS9 A;  4FF1 A;  4FZ4 A;  3C2P A;  4QIC A;  2EC5 A;  2F6L A;  3N0R A;  4G97 A;  3C3L A;  3X29 A;  2AZE A;  1K93 A;  1PK0 A;  1SC5 A;  4AI6 A;  1XFX A;  3Q23 A;  2LFW A;  4AKH A;  1RP3 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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4HKRA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations