4HKRA

Calcium release-activated calcium (crac) channel orai
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
191
structure length
165
Chain Sequence
TYLSWRKLQLSRAKLKASSKTSALLSGFAMVAMVEVQMLIAFAICTTLLVAVHMLALMISTCILPNPHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSRRAAWSATVVLIPVMIIFMAFAIHFYRSLVSHKYEVTVSGIRELEMLKEQMEQDHLEHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the calcium release-activated calcium channel Orai.
pubmed doi rcsb
molecule tags Transport protein
source organism Drosophila melanogaster
molecule keywords Calcium release-activated calcium channel protein 1
total genus 69
structure length 165
sequence length 191
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07856 Orai-1 Mediator of CRAC channel activity
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.140 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 4hkrA00
4HKRA 4HKSA
chains in the Genus database with same CATH superfamily
4HKRA 4G5EA 2ZDXA 1JM6A 4HR3A 3II9A 1Y8OA 2C12A 3Q22A 4LQQB 4LQSB 3Q23A 5GJVE 5M4PA 4L3ZA 2CJ6A 4Q0TA 2JIFA 2YYMA 4H85A 3C3LA 1FS9A 2E80A 3B96A 3X0XA 5B5WA 1X8ZA 3D6BA 3LGQA 4L3YA 2BU7A 1K90A 1R2JA 4U83A 3GM6A 2EBFX 3SF6A 4FF1A 1SK6A 5K3GA 3MPJA 3MKHA 3C46A 4X28A 4IRNA 4WJYA 2PNRA 1OAHA 1XFYA 4V25A 1XFWA 4JEKA 1XFXA 2J7AA 4RM7A 3RKHA 3AFEA 4E01A 3TZ5A 1XFUA 3D9EA 3SXQA 3CRKA 2YGWA 2Z1QA 1K8TA 2ZO5A 3PFDA 1EGEA 2BU8A 2RFQA 1XG2B 1SIQA 1PK0A 2IX5A 1EGCA 2FP1A 2Q8GA 2AZEA 1U8VA 3AFFA 2OEXA 3FO3A 2VR0A 4V26A 1RJ4A 2BU6A 2EC5A 3D9DA 4MP2A 3F29A 4E02A 4G97A 3TZ4A 1EGDA 4KSFA 1GJVA 4J1VA 3VKGA 2ZAFA 2HJNA 2YYGA 2R0NA 1BUCA 3EONA 3OIBA 4P13A 3OWAA 2ZKJA 2EBAA 3X0YA 3MMOA 3MPIA 4HKSA 4AKHA 1GU6A 4E00A 2OT4A 3Q24A 3BNGA 4IV6A 4F0XA 3EOMA 4JIZA 2XS8A 4OO2A 3TORA 3D9GA 5J6AA 1R3BA 1T9GA 3KMLA 4XVXA 2C0UA 4ZXVA 4AKIA 3UBRA 1FS7A 2FP2A 2LFWA 2YYLA 3HWCA 3BNFA 2VF1A 1JQIA 4Q5CA 3D9FA 1K93A 2D29A 1W07A 3MXLA 2RF7A 3M9VA 3OWMA 4KCFA 1X91A 2BTZA 2PG0A 1FS8A 2RDZA 2EBHX 2OR0A 2DDHA 3BNJA 1WS9A 4L3XA 2R05A 3NF4A 4O5MA 5BRMA 4FF3A 3VKHA 4L38A 3TTBA 5K3JA 2YYJA 5M4KA 4MPEA 1GKZA 1Y8NA 5M4MA 4FZ4A 2XS1A 4FF4A 2DVLA 1X90A 4H81A 4Q1OA 2CJ5A 4L1FA 4MP7A 3SWOA 2CJ4A 3D1IA 4M9AA 1QDBA 2IX6A 2XQRB 3LG1A 4JIOA 4KSAA 2Q8FA 2CJ7A 3VADA 2YYKA 1UKWA 2JBRA 4KS9A 3TZ2A 4AKGA 2BU2A 3N0RA 4QICA 1RJ1A 2JBTA 3SCEA 5BRKA 1GKXA 3TZ0A 4MPNA 2JBSA 3GQTA 4Q5BA 1IVHA 3R7KA 1XFZA 4Q4UA 4H7QA 1UDYA 3MDDA 3CRLA 2CX9A 3CE2A 3C2PA 2Q8IA 2R0MA 2WBIA 2ZDYA 3P4TA 1Y8PA 5M4NA 3L1TA 3S7WA 3X29A 2Q8HA 1SIRA 2E0AA 5J71A 4X28C 1Y0VA 5B6BA 3FCJA 2F6LA 2GBBA 2OEVA 2UXWA 4MPCA 5K3HA 3Q0AA 2FONA 2REHA 2PO4A 1SC5A 1IS2A 2OJQA 3MDEA 4AI6A 1S26A 2AO2A 3GNCA 2CJ8A 3D2RA 1RX0A 4DOYA 4FF2A 4W9UA 4DZYA 2A1TA 3BNHA 1RP3A 2R03A 2QR4A 2YYIA 3UU9A 1PI1A 5K3IA 4NXLA 5GJWE 4N5FA 2BU5A 1XFVA 4KTOA 2R02A 4Q17A 1LVCA 2VIGA 5B5VA 2E81A 4P79A 4ZYJA
chains in the Genus database with same CATH topology
2AZEA 4HKRA 3CE2A 3C2PA 2EBHX 3Q22A 3VKHA 3Q23A 4FF3A 2EC5A 5GJVE 4G97A 3X29A 4KSFA 3C3LA 3VKGA 4FZ4A 1Y0VA 1K90A 4FF4A 2F6LA 2GBBA 2EBFX 3Q0AA 4FF1A 1SK6A 2PO4A 1SC5A 3C46A 4AI6A 1S26A 2AO2A 4KSAA 4HKSA 4AKHA 1XFYA 1XFWA 1XFXA 3Q24A 4FF2A 4F0XA 4KS9A 1RP3A 4AKGA 2QR4A 4AKIA 1XFUA 3N0RA 3KMLA 4QICA 5GJWE 4P79A 1XFVA 2YGWA 2FP2A 2LFWA 1LVCA 1K8TA 1XFZA 2VF1A 1K93A 1PK0A 2FP1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HKR A;  4HKS A; 
#chains in the Genus database with same CATH topology
 4HKR A;  4G5E A;  2ZDX A;  1JM6 A;  4HR3 A;  3II9 A;  1Y8O A;  2C12 A;  3Q22 A;  4LQQ B;  4LQS B;  3Q23 A;  5GJV E;  5M4P A;  4L3Z A;  2CJ6 A;  4Q0T A;  2JIF A;  2YYM A;  4H85 A;  3C3L A;  1FS9 A;  2E80 A;  3B96 A;  3X0X A;  5B5W A;  1X8Z A;  3D6B A;  3LGQ A;  4L3Y A;  2BU7 A;  1K90 A;  1R2J A;  4U83 A;  3GM6 A;  2EBF X;  3SF6 A;  4FF1 A;  1SK6 A;  5K3G A;  3MPJ A;  3MKH A;  3C46 A;  4X28 A;  4IRN A;  4WJY A;  2PNR A;  1OAH A;  1XFY A;  4V25 A;  1XFW A;  4JEK A;  1XFX A;  2J7A A;  4RM7 A;  3RKH A;  3AFE A;  4E01 A;  3TZ5 A;  1XFU A;  3D9E A;  3SXQ A;  3CRK A;  2YGW A;  2Z1Q A;  1K8T A;  2ZO5 A;  3PFD A;  1EGE A;  2BU8 A;  2RFQ A;  1XG2 B;  1SIQ A;  1PK0 A;  2IX5 A;  1EGC A;  2FP1 A;  2Q8G A;  2AZE A;  1U8V A;  3AFF A;  2OEX A;  3FO3 A;  2VR0 A;  4V26 A;  1RJ4 A;  2BU6 A;  2EC5 A;  3D9D A;  4MP2 A;  3F29 A;  4E02 A;  4G97 A;  3TZ4 A;  1EGD A;  4KSF A;  1GJV A;  4J1V A;  3VKG A;  2ZAF A;  2HJN A;  2YYG A;  2R0N A;  1BUC A;  3EON A;  3OIB A;  4P13 A;  3OWA A;  2ZKJ A;  2EBA A;  3X0Y A;  3MMO A;  3MPI A;  4HKS A;  4AKH A;  1GU6 A;  4E00 A;  2OT4 A;  3Q24 A;  3BNG A;  4IV6 A;  4F0X A;  3EOM A;  4JIZ A;  2XS8 A;  4OO2 A;  3TOR A;  3D9G A;  5J6A A;  1R3B A;  1T9G A;  3KML A;  4XVX A;  2C0U A;  4ZXV A;  4AKI A;  3UBR A;  1FS7 A;  2FP2 A;  2LFW A;  2YYL A;  3HWC A;  3BNF A;  2VF1 A;  1JQI A;  4Q5C A;  3D9F A;  1K93 A;  2D29 A;  1W07 A;  3MXL A;  2RF7 A;  3M9V A;  3OWM A;  4KCF A;  1X91 A;  2BTZ A;  2PG0 A;  1FS8 A;  2RDZ A;  2EBH X;  2OR0 A;  2DDH A;  3BNJ A;  1WS9 A;  4L3X A;  2R05 A;  3NF4 A;  4O5M A;  5BRM A;  4FF3 A;  3VKH A;  4L38 A;  3TTB A;  5K3J A;  2YYJ A;  5M4K A;  4MPE A;  1GKZ A;  1Y8N A;  5M4M A;  4FZ4 A;  2XS1 A;  4FF4 A;  2DVL A;  1X90 A;  4H81 A;  4Q1O A;  2CJ5 A;  4L1F A;  4MP7 A;  3SWO A;  2CJ4 A;  3D1I A;  4M9A A;  1QDB A;  2IX6 A;  2XQR B;  3LG1 A;  4JIO A;  4KSA A;  2Q8F A;  2CJ7 A;  3VAD A;  2YYK A;  1UKW A;  2JBR A;  4KS9 A;  3TZ2 A;  4AKG A;  2BU2 A;  3N0R A;  4QIC A;  1RJ1 A;  2JBT A;  3SCE A;  5BRK A;  1GKX A;  3TZ0 A;  4MPN A;  2JBS A;  3GQT A;  4Q5B A;  1IVH A;  3R7K A;  1XFZ A;  4Q4U A;  4H7Q A;  1UDY A;  3MDD A;  3CRL A;  2CX9 A;  3CE2 A;  3C2P A;  2Q8I A;  2R0M A;  2WBI A;  2ZDY A;  3P4T A;  1Y8P A;  5M4N A;  3L1T A;  3S7W A;  3X29 A;  2Q8H A;  1SIR A;  2E0A A;  5J71 A;  4X28 C;  1Y0V A;  5B6B A;  3FCJ A;  2F6L A;  2GBB A;  2OEV A;  2UXW A;  4MPC A;  5K3H A;  3Q0A A;  2FON A;  2REH A;  2PO4 A;  1SC5 A;  1IS2 A;  2OJQ A;  3MDE A;  4AI6 A;  1S26 A;  2AO2 A;  3GNC A;  2CJ8 A;  3D2R A;  1RX0 A;  4DOY A;  4FF2 A;  4W9U A;  4DZY A;  2A1T A;  3BNH A;  1RP3 A;  2R03 A;  2QR4 A;  2YYI A;  3UU9 A;  1PI1 A;  5K3I A;  4NXL A;  5GJW E;  4N5F A;  2BU5 A;  1XFV A;  4KTO A;  2R02 A;  4Q17 A;  1LVC A;  2VIG A;  5B5V A;  2E81 A;  4P79 A;  4ZYJ A; 
#chains in the Genus database with same CATH homology
 2AZE A;  4HKR A;  3CE2 A;  3C2P A;  2EBH X;  3Q22 A;  3VKH A;  3Q23 A;  4FF3 A;  2EC5 A;  5GJV E;  4G97 A;  3X29 A;  4KSF A;  3C3L A;  3VKG A;  4FZ4 A;  1Y0V A;  1K90 A;  4FF4 A;  2F6L A;  2GBB A;  2EBF X;  3Q0A A;  4FF1 A;  1SK6 A;  2PO4 A;  1SC5 A;  3C46 A;  4AI6 A;  1S26 A;  2AO2 A;  4KSA A;  4HKS A;  4AKH A;  1XFY A;  1XFW A;  1XFX A;  3Q24 A;  4FF2 A;  4F0X A;  4KS9 A;  1RP3 A;  4AKG A;  2QR4 A;  4AKI A;  1XFU A;  3N0R A;  3KML A;  4QIC A;  5GJW E;  4P79 A;  1XFV A;  2YGW A;  2FP2 A;  2LFW A;  1LVC A;  1K8T A;  1XFZ A;  2VF1 A;  1K93 A;  1PK0 A;  2FP1 A; 
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