4J1VA

Functional and structural studies of mobkl1b, a salvador/warts/hippo tumor suppressor pathway, in hcv replication
Total Genus 58
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
172
structure length
166
Chain Sequence
LRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Peptide binding protein/viral protein
source organism Homo sapiens
publication title Seed Sequence-Matched Controls Reveal Limitations of Small Interfering RNA Knockdown in Functional and Structural Studies of Hepatitis C Virus NS5A-MOBKL1B Interaction.
pubmed doi rcsb
molecule keywords MOB kinase activator 1A
total genus 58
structure length 166
sequence length 172
chains with identical sequence C
ec nomenclature
pdb deposition date 2013-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03637 Mob1_phocein Mob1/phocein family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.30 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 MOB kinase activator 4j1vA00
1PI1A 4LQSB 5BRMA 5B6BA 2HJNA 5B5WA 4JIZA 5BRKA 4LQQB 4J1VA 5B5VA 1R3BA
chains in the Genus database with same CATH superfamily
1SIRA 2Z1QA 2HJNA 1W07A 2R0MA 3OIBA 3TZ0A 2JIFA 4MP2A 3PFDA 5M4MA 5B5WA 2CX9A 3OWAA 3Q23A 3D2RA 3SF6A 4U83A 2BU8A 4AKHA 4Q5BA 4G97A 4HR3A 3UU9A 5B6BA 2ZKJA 1XFYA 2Q8GA 3LG1A 1XFXA 3D9GA 4KTOA 5GJWE 3S7WA 1QDBA 5J71A 2RF7A 1FS9A 2BU6A 2PO4A 3D9FA 3P4TA 2QR4A 4ZYJA 4IRNA 4Q17A 2DDHA 2XS1A 1XFVA 1RX0A 3CRKA 1XG2B 2OEVA 3BNFA 2XQRB 1Y8NA 2RDZA 2ZDYA 2CJ7A 4JIZA 4FF3A 2ZAFA 4P13A 4H85A 5BRMA 3TTBA 1SK6A 1Y8OA 4DOYA 1RJ4A 3EOMA 2Q8IA 1GKXA 2CJ4A 3GNCA 3B96A 5J6AA 3LGQA 2E80A 3D6BA 4P79A 1EGDA 1SC5A 2OR0A 2VR0A 2C12A 2WBIA 3BNGA 2YYKA 3X0YA 3C46A 3VKGA 1XFZA 4Q1OA 3SCEA 4MP7A 4Q5CA 1OAHA 4V26A 1PK0A 2JBTA 4QICA 3MDDA 1XFWA 4MPCA 2IX6A 1RP3A 2E0AA 2R03A 3MPJA 3F29A 5M4NA 2CJ8A 4AI6A 4NXLA 3MXLA 1EGCA 2YGWA 4XVXA 2OT4A 2FP1A 2YYGA 3RKHA 1U8VA 4X28A 1S26A 2GBBA 4KSAA 1LVCA 4E01A 2RFQA 3Q22A 1JM6A 4LQSB 4M9AA 1RJ1A 3TZ5A 3C3LA 3KMLA 1Y8PA 2E81A 3BNJA 3D1IA 3II9A 3VADA 4FF1A 3VKHA 4Q4UA 4L3XA 1FS7A 4L3ZA 4H81A 4KCFA 5B5VA 4OO2A 1BUCA 1UKWA 2VIGA 3N0RA 4H7QA 3X0XA 1T9GA 3FCJA 1EGEA 1GKZA 3CRLA 4E00A 1JQIA 2R0NA 2YYMA 5GJVE 3D9EA 4IV6A 3EONA 4L3YA 1X8ZA 3UBRA 2J7AA 4FF4A 2BU2A 1K90A 2YYIA 4KS9A 1Y0VA 4KSFA 3C2PA 1SIQA 5BRKA 1WS9A 2PNRA 3AFFA 4MPNA 5K3JA 3Q24A 2FP2A 3D9DA 2Q8FA 5M4PA 2CJ6A 2ZO5A 5K3GA 4F0XA 2BU7A 4AKGA 4J1VA 1GJVA 1UDYA 3GM6A 2EBAA 3MPIA 3SWOA 3M9VA 3TZ2A 2PG0A 2IX5A 3SXQA 2OEXA 1X90A 2UXWA 4W9UA 4DZYA 3OWMA 4JIOA 1XFUA 3NF4A 1PI1A 2YYJA 2BU5A 2Q8HA 3TZ4A 2EBHX 3Q0AA 3CE2A 4ZXVA 4X28C 4WJYA 4FZ4A 4RM7A 2F6LA 3AFEA 2LFWA 3HWCA 3X29A 4L38A 2FONA 2REHA 4O5MA 1IS2A 4V25A 2XS8A 2ZDXA 2BTZA 3MDEA 2EC5A 4LQQB 2D29A 4MPEA 3L1TA 2AZEA 1R2JA 1R3BA 3R7KA 3BNHA 1K93A 1FS8A 3GQTA 3FO3A 4E02A 2A1TA 1IVHA 2AO2A 2VF1A 4G5EA 5K3IA 2YYLA 3MKHA 1GU6A 2DVLA 5K3HA 2JBRA 5M4KA 4FF2A 4JEKA 4HKRA 3TORA 2R02A 4N5FA 2EBFX 1X91A 3MMOA 1K8TA 2CJ5A 2JBSA 2OJQA 2C0UA 2R05A 4HKSA 4Q0TA 4L1FA 4AKIA
chains in the Genus database with same CATH topology
1PI1A 4LQSB 5BRMA 5B6BA 2HJNA 5B5WA 4JIZA 5BRKA 4LQQB 4J1VA 5B5VA 1R3BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PI1 A;  4LQS B;  5BRM A;  5B6B A;  2HJN A;  5B5W A;  4JIZ A;  5BRK A;  4LQQ B;  4J1V A;  5B5V A;  1R3B A; 
#chains in the Genus database with same CATH topology
 1SIR A;  2Z1Q A;  2HJN A;  1W07 A;  2R0M A;  3OIB A;  3TZ0 A;  2JIF A;  4MP2 A;  3PFD A;  5M4M A;  5B5W A;  2CX9 A;  3OWA A;  3Q23 A;  3D2R A;  3SF6 A;  4U83 A;  2BU8 A;  4AKH A;  4Q5B A;  4G97 A;  4HR3 A;  3UU9 A;  5B6B A;  2ZKJ A;  1XFY A;  2Q8G A;  3LG1 A;  1XFX A;  3D9G A;  4KTO A;  5GJW E;  3S7W A;  1QDB A;  5J71 A;  2RF7 A;  1FS9 A;  2BU6 A;  2PO4 A;  3D9F A;  3P4T A;  2QR4 A;  4ZYJ A;  4IRN A;  4Q17 A;  2DDH A;  2XS1 A;  1XFV A;  1RX0 A;  3CRK A;  1XG2 B;  2OEV A;  3BNF A;  2XQR B;  1Y8N A;  2RDZ A;  2ZDY A;  2CJ7 A;  4JIZ A;  4FF3 A;  2ZAF A;  4P13 A;  4H85 A;  5BRM A;  3TTB A;  1SK6 A;  1Y8O A;  4DOY A;  1RJ4 A;  3EOM A;  2Q8I A;  1GKX A;  2CJ4 A;  3GNC A;  3B96 A;  5J6A A;  3LGQ A;  2E80 A;  3D6B A;  4P79 A;  1EGD A;  1SC5 A;  2OR0 A;  2VR0 A;  2C12 A;  2WBI A;  3BNG A;  2YYK A;  3X0Y A;  3C46 A;  3VKG A;  1XFZ A;  4Q1O A;  3SCE A;  4MP7 A;  4Q5C A;  1OAH A;  4V26 A;  1PK0 A;  2JBT A;  4QIC A;  3MDD A;  1XFW A;  4MPC A;  2IX6 A;  1RP3 A;  2E0A A;  2R03 A;  3MPJ A;  3F29 A;  5M4N A;  2CJ8 A;  4AI6 A;  4NXL A;  3MXL A;  1EGC A;  2YGW A;  4XVX A;  2OT4 A;  2FP1 A;  2YYG A;  3RKH A;  1U8V A;  4X28 A;  1S26 A;  2GBB A;  4KSA A;  1LVC A;  4E01 A;  2RFQ A;  3Q22 A;  1JM6 A;  4LQS B;  4M9A A;  1RJ1 A;  3TZ5 A;  3C3L A;  3KML A;  1Y8P A;  2E81 A;  3BNJ A;  3D1I A;  3II9 A;  3VAD A;  4FF1 A;  3VKH A;  4Q4U A;  4L3X A;  1FS7 A;  4L3Z A;  4H81 A;  4KCF A;  5B5V A;  4OO2 A;  1BUC A;  1UKW A;  2VIG A;  3N0R A;  4H7Q A;  3X0X A;  1T9G A;  3FCJ A;  1EGE A;  1GKZ A;  3CRL A;  4E00 A;  1JQI A;  2R0N A;  2YYM A;  5GJV E;  3D9E A;  4IV6 A;  3EON A;  4L3Y A;  1X8Z A;  3UBR A;  2J7A A;  4FF4 A;  2BU2 A;  1K90 A;  2YYI A;  4KS9 A;  1Y0V A;  4KSF A;  3C2P A;  1SIQ A;  5BRK A;  1WS9 A;  2PNR A;  3AFF A;  4MPN A;  5K3J A;  3Q24 A;  2FP2 A;  3D9D A;  2Q8F A;  5M4P A;  2CJ6 A;  2ZO5 A;  5K3G A;  4F0X A;  2BU7 A;  4AKG A;  4J1V A;  1GJV A;  1UDY A;  3GM6 A;  2EBA A;  3MPI A;  3SWO A;  3M9V A;  3TZ2 A;  2PG0 A;  2IX5 A;  3SXQ A;  2OEX A;  1X90 A;  2UXW A;  4W9U A;  4DZY A;  3OWM A;  4JIO A;  1XFU A;  3NF4 A;  1PI1 A;  2YYJ A;  2BU5 A;  2Q8H A;  3TZ4 A;  2EBH X;  3Q0A A;  3CE2 A;  4ZXV A;  4X28 C;  4WJY A;  4FZ4 A;  4RM7 A;  2F6L A;  3AFE A;  2LFW A;  3HWC A;  3X29 A;  4L38 A;  2FON A;  2REH A;  4O5M A;  1IS2 A;  4V25 A;  2XS8 A;  2ZDX A;  2BTZ A;  3MDE A;  2EC5 A;  4LQQ B;  2D29 A;  4MPE A;  3L1T A;  2AZE A;  1R2J A;  1R3B A;  3R7K A;  3BNH A;  1K93 A;  1FS8 A;  3GQT A;  3FO3 A;  4E02 A;  2A1T A;  1IVH A;  2AO2 A;  2VF1 A;  4G5E A;  5K3I A;  2YYL A;  3MKH A;  1GU6 A;  2DVL A;  5K3H A;  2JBR A;  5M4K A;  4FF2 A;  4JEK A;  4HKR A;  3TOR A;  2R02 A;  4N5F A;  2EBF X;  1X91 A;  3MMO A;  1K8T A;  2CJ5 A;  2JBS A;  2OJQ A;  2C0U A;  2R05 A;  4HKS A;  4Q0T A;  4L1F A;  4AKI A; 
#chains in the Genus database with same CATH homology
 1PI1 A;  4LQS B;  5BRM A;  5B6B A;  2HJN A;  5B5W A;  4JIZ A;  5BRK A;  4LQQ B;  4J1V A;  5B5V A;  1R3B A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...