4J1VA

Functional and structural studies of mobkl1b, a salvador/warts/hippo tumor suppressor pathway, in hcv replication
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
172
structure length
166
Chain Sequence
LRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Seed Sequence-Matched Controls Reveal Limitations of Small Interfering RNA Knockdown in Functional and Structural Studies of Hepatitis C Virus NS5A-MOBKL1B Interaction.
pubmed doi rcsb
molecule tags Peptide binding protein/viral protein
source organism Homo sapiens
molecule keywords MOB kinase activator 1A
total genus 58
structure length 166
sequence length 172
chains with identical sequence C
ec nomenclature
pdb deposition date 2013-02-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03637 Mob1_phocein Mob1/phocein family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.30 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 MOB kinase activator 4j1vA00
4LQSB 4LQQB 5BRKA 4J1VA 5B5VA 5BRMA 5B5WA 4JIZA 1R3BA 5B6BA 2HJNA 1PI1A
chains in the Genus database with same CATH superfamily
1JQIA 2FP1A 3BNJA 4XVXA 3BNGA 1XFZA 2BU2A 3L1TA 3SCEA 1XFWA 2QR4A 3UBRA 2E80A 4HKSA 3B96A 2J7AA 4JEKA 4OO2A 3X0YA 4O5MA 4L38A 1EGEA 4FZ4A 4LQQB 5J6AA 2Q8HA 5BRKA 4Q5BA 4X28A 2PNRA 5K3HA 3X0XA 3Q24A 2CJ6A 1Y8NA 2YYJA 3TZ5A 3D9DA 4Q17A 3TTBA 2Z1QA 2CX9A 1EGDA 3GQTA 1T9GA 4KTOA 1SIQA 3MMOA 3TZ4A 2C12A 4MPCA 5B6BA 3TORA 1K93A 1GKXA 2ZKJA 4G97A 1XFUA 4X28C 3Q22A 2YYIA 2YYKA 3N0RA 2D29A 3CRLA 4L1FA 1GU6A 5GJWE 2E81A 5K3JA 1RJ4A 2DDHA 2CJ8A 2ZDYA 3FO3A 2PO4A 2EBAA 2PG0A 4RM7A 3SF6A 2BU6A 2XS1A 3CE2A 2OJQA 4ZXVA 4KSAA 3D9EA 2RDZA 2FP2A 1WS9A 2EC5A 2OEVA 2XQRB 1X90A 2YGWA 4FF4A 2A1TA 1RJ1A 3AFFA 3AFEA 4MP7A 1SC5A 1IS2A 4L3ZA 2AO2A 2XS8A 3GM6A 4MPEA 1S26A 2EBFX 2LFWA 2ZAFA 4F0XA 1PI1A 2RF7A 2BU5A 1Y8OA 2JIFA 4LQSB 1QDBA 2VF1A 5B5VA 1FS9A 3R7KA 3MPJA 2CJ4A 2FONA 2Q8FA 3VKHA 2JBTA 2UXWA 3D9FA 1XG2B 2IX5A 3C2PA 3Q23A 2YYLA 1UKWA 4MPNA 4DOYA 3OWAA 3BNFA 5M4PA 4AKGA 4Q4UA 3KMLA 4FF3A 2RFQA 4E00A 3II9A 4IV6A 4DZYA 4M9AA 1FS8A 2EBHX 2OEXA 3M9VA 1LVCA 5GJVE 4Q0TA 1IVHA 3VADA 3X29A 1BUCA 5BRMA 2JBSA 1R3BA 3SXQA 4V25A 3GNCA 1XFVA 4WJYA 3C3LA 2R02A 3MPIA 2BTZA 5K3IA 4G5EA 4N5FA 5M4NA 4E02A 3OWMA 4QICA 2BU7A 4HR3A 2HJNA 1EGCA 4U83A 4KSFA 3F29A 4AKIA 2R0NA 3MDEA 3NF4A 3PFDA 1SK6A 3OIBA 2F6LA 4H81A 4H85A 5M4MA 3C46A 4JIOA 1Y8PA 2C0UA 2IX6A 2R05A 3LG1A 5M4KA 4AI6A 2YYGA 2CJ5A 2GBBA 4Q1OA 2REHA 3EONA 4HKRA 1XFYA 1JM6A 3FCJA 1RP3A 4KS9A 4L3YA 1RX0A 3MKHA 2Q8GA 1XFXA 2VR0A 3D2RA 1GJVA 1Y0VA 1K90A 2E0AA 4W9UA 2ZO5A 4FF2A 1PK0A 4H7QA 4AKHA 5J71A 2BU8A 2YYMA 3BNHA 3HWCA 5K3GA 1U8VA 2VIGA 4J1VA 3MDDA 3SWOA 3D1IA 4ZYJA 4L3XA 1R2JA 2AZEA 4KCFA 2DVLA 1SIRA 3S7WA 3RKHA 2JBRA 4Q5CA 4V26A 4IRNA 1FS7A 1UDYA 1X91A 1OAHA 2R0MA 3CRKA 3LGQA 3MXLA 4JIZA 2OT4A 1X8ZA 1K8TA 5B5WA 3VKGA 3D9GA 3D6BA 2Q8IA 1W07A 4MP2A 4P13A 4E01A 2ZDXA 4P79A 3UU9A 3TZ0A 3Q0AA 2R03A 4NXLA 3EOMA 3TZ2A 1GKZA 2CJ7A 2OR0A 4FF1A 2WBIA 3P4TA
chains in the Genus database with same CATH topology
4LQSB 4LQQB 5BRKA 4J1VA 5B5VA 5BRMA 5B5WA 4JIZA 1R3BA 5B6BA 2HJNA 1PI1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LQS B;  4LQQ B;  5BRK A;  4J1V A;  5B5V A;  5BRM A;  5B5W A;  4JIZ A;  1R3B A;  5B6B A;  2HJN A;  1PI1 A; 
#chains in the Genus database with same CATH topology
 1JQI A;  2FP1 A;  3BNJ A;  4XVX A;  3BNG A;  1XFZ A;  2BU2 A;  3L1T A;  3SCE A;  1XFW A;  2QR4 A;  3UBR A;  2E80 A;  4HKS A;  3B96 A;  2J7A A;  4JEK A;  4OO2 A;  3X0Y A;  4O5M A;  4L38 A;  1EGE A;  4FZ4 A;  4LQQ B;  5J6A A;  2Q8H A;  5BRK A;  4Q5B A;  4X28 A;  2PNR A;  5K3H A;  3X0X A;  3Q24 A;  2CJ6 A;  1Y8N A;  2YYJ A;  3TZ5 A;  3D9D A;  4Q17 A;  3TTB A;  2Z1Q A;  2CX9 A;  1EGD A;  3GQT A;  1T9G A;  4KTO A;  1SIQ A;  3MMO A;  3TZ4 A;  2C12 A;  4MPC A;  5B6B A;  3TOR A;  1K93 A;  1GKX A;  2ZKJ A;  4G97 A;  1XFU A;  4X28 C;  3Q22 A;  2YYI A;  2YYK A;  3N0R A;  2D29 A;  3CRL A;  4L1F A;  1GU6 A;  5GJW E;  2E81 A;  5K3J A;  1RJ4 A;  2DDH A;  2CJ8 A;  2ZDY A;  3FO3 A;  2PO4 A;  2EBA A;  2PG0 A;  4RM7 A;  3SF6 A;  2BU6 A;  2XS1 A;  3CE2 A;  2OJQ A;  4ZXV A;  4KSA A;  3D9E A;  2RDZ A;  2FP2 A;  1WS9 A;  2EC5 A;  2OEV A;  2XQR B;  1X90 A;  2YGW A;  4FF4 A;  2A1T A;  1RJ1 A;  3AFF A;  3AFE A;  4MP7 A;  1SC5 A;  1IS2 A;  4L3Z A;  2AO2 A;  2XS8 A;  3GM6 A;  4MPE A;  1S26 A;  2EBF X;  2LFW A;  2ZAF A;  4F0X A;  1PI1 A;  2RF7 A;  2BU5 A;  1Y8O A;  2JIF A;  4LQS B;  1QDB A;  2VF1 A;  5B5V A;  1FS9 A;  3R7K A;  3MPJ A;  2CJ4 A;  2FON A;  2Q8F A;  3VKH A;  2JBT A;  2UXW A;  3D9F A;  1XG2 B;  2IX5 A;  3C2P A;  3Q23 A;  2YYL A;  1UKW A;  4MPN A;  4DOY A;  3OWA A;  3BNF A;  5M4P A;  4AKG A;  4Q4U A;  3KML A;  4FF3 A;  2RFQ A;  4E00 A;  3II9 A;  4IV6 A;  4DZY A;  4M9A A;  1FS8 A;  2EBH X;  2OEX A;  3M9V A;  1LVC A;  5GJV E;  4Q0T A;  1IVH A;  3VAD A;  3X29 A;  1BUC A;  5BRM A;  2JBS A;  1R3B A;  3SXQ A;  4V25 A;  3GNC A;  1XFV A;  4WJY A;  3C3L A;  2R02 A;  3MPI A;  2BTZ A;  5K3I A;  4G5E A;  4N5F A;  5M4N A;  4E02 A;  3OWM A;  4QIC A;  2BU7 A;  4HR3 A;  2HJN A;  1EGC A;  4U83 A;  4KSF A;  3F29 A;  4AKI A;  2R0N A;  3MDE A;  3NF4 A;  3PFD A;  1SK6 A;  3OIB A;  2F6L A;  4H81 A;  4H85 A;  5M4M A;  3C46 A;  4JIO A;  1Y8P A;  2C0U A;  2IX6 A;  2R05 A;  3LG1 A;  5M4K A;  4AI6 A;  2YYG A;  2CJ5 A;  2GBB A;  4Q1O A;  2REH A;  3EON A;  4HKR A;  1XFY A;  1JM6 A;  3FCJ A;  1RP3 A;  4KS9 A;  4L3Y A;  1RX0 A;  3MKH A;  2Q8G A;  1XFX A;  2VR0 A;  3D2R A;  1GJV A;  1Y0V A;  1K90 A;  2E0A A;  4W9U A;  2ZO5 A;  4FF2 A;  1PK0 A;  4H7Q A;  4AKH A;  5J71 A;  2BU8 A;  2YYM A;  3BNH A;  3HWC A;  5K3G A;  1U8V A;  2VIG A;  4J1V A;  3MDD A;  3SWO A;  3D1I A;  4ZYJ A;  4L3X A;  1R2J A;  2AZE A;  4KCF A;  2DVL A;  1SIR A;  3S7W A;  3RKH A;  2JBR A;  4Q5C A;  4V26 A;  4IRN A;  1FS7 A;  1UDY A;  1X91 A;  1OAH A;  2R0M A;  3CRK A;  3LGQ A;  3MXL A;  4JIZ A;  2OT4 A;  1X8Z A;  1K8T A;  5B5W A;  3VKG A;  3D9G A;  3D6B A;  2Q8I A;  1W07 A;  4MP2 A;  4P13 A;  4E01 A;  2ZDX A;  4P79 A;  3UU9 A;  3TZ0 A;  3Q0A A;  2R03 A;  4NXL A;  3EOM A;  3TZ2 A;  1GKZ A;  2CJ7 A;  2OR0 A;  4FF1 A;  2WBI A;  3P4T A; 
#chains in the Genus database with same CATH homology
 4LQS B;  4LQQ B;  5BRK A;  4J1V A;  5B5V A;  5BRM A;  5B5W A;  4JIZ A;  1R3B A;  5B6B A;  2HJN A;  1PI1 A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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