4P79A

Crystal structure of mouse claudin-15
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
189
structure length
181
Chain Sequence
SEFMSVAVETFGFFMSALGLLMLGLTLSNSYWRVSTNTIFENLWYSCATDSLGVSNCWDFPSMLALSGYVQGCRALMITAILLGFLGLFLGMVGLRATNVGNMDLSKKAKLLAIAGTLHILAGACGMVAISWYAVNITTDFFNPLYAGTKYELGPALYLGWSASLLSILGGICVFSTAAAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a claudin provides insight into the architecture of tight junctions.
pubmed doi rcsb
molecule tags Cell adhesion
source organism Mus musculus
molecule keywords Claudin-15
total genus 59
structure length 181
sequence length 189
ec nomenclature
pdb deposition date 2014-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00822 PMP22_Claudin PMP-22/EMP/MP20/Claudin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.150 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 4p79A00
5GJVE 4P79A 5GJWE 3X29A
chains in the Genus database with same CATH superfamily
3LGQA 2E81A 1FS9A 5B5WA 4H81A 3BNGA 2Q8GA 1UKWA 3EONA 3SXQA 3TZ2A 4FZ4A 2QR4A 1XFYA 2AO2A 4AKGA 4IRNA 3C2PA 3S7WA 1EGEA 5BRKA 3C46A 3P4TA 2BU5A 4KTOA 4L3XA 2IX6A 2FP1A 1GKZA 1SK6A 1R3BA 2Q8FA 3PFDA 1PI1A 2CJ8A 1FS7A 3NF4A 4H85A 3D9DA 5K3GA 4L3YA 2DVLA 2R0NA 2YYLA 3CRKA 4X28A 1RP3A 1WS9A 2YYMA 4Q5BA 3OWAA 2OT4A 2EBAA 2XS1A 2HJNA 2CJ7A 3OWMA 4JIZA 5GJWE 3CRLA 1PK0A 4ZYJA 2AZEA 3B96A 3Q22A 2E80A 4U83A 3TZ0A 2YYIA 3D9GA 2JBSA 1R2JA 4MPEA 3TZ5A 5B6BA 3X0XA 2YGWA 5M4MA 4FF1A 5K3JA 3RKHA 1JM6A 1Y8OA 1X90A 2OEVA 4OO2A 2BTZA 5J71A 1SIRA 2BU8A 4QICA 3GNCA 4WJYA 2ZKJA 1Y8PA 2RDZA 2ZDYA 5M4PA 2JBTA 2ZAFA 3BNHA 1JQIA 4V26A 3UBRA 4RM7A 1IVHA 2RFQA 3L1TA 4W9UA 4ZXVA 1UDYA 2OR0A 2R03A 2RF7A 3KMLA 4AKHA 3D9EA 4G97A 2E0AA 3D6BA 1XG2B 1XFUA 4E01A 4F0XA 3HWCA 4Q5CA 4G5EA 3TZ4A 5J6AA 1SIQA 3FCJA 2C12A 2PO4A 3TORA 3VADA 3EOMA 3MMOA 3FO3A 1GJVA 1BUCA 1X8ZA 4MPNA 5BRMA 2CJ6A 3X29A 2J7AA 3MKHA 4FF2A 2R05A 4LQSB 3MDEA 4NXLA 3GM6A 2Q8HA 2R02A 4MP7A 4DOYA 2YYGA 4KSAA 2UXWA 5M4NA 2LFWA 2OJQA 1Y0VA 2CJ4A 1RJ4A 5K3IA 2YYJA 2D29A 2YYKA 4N5FA 1QDBA 2C0UA 4P13A 2GBBA 3D9FA 3UU9A 3SWOA 4LQQB 3C3LA 1GKXA 3N0RA 2VIGA 1K90A 2BU6A 1XFWA 4Q0TA 2CJ5A 4MPCA 1T9GA 4L3ZA 4E02A 4HR3A 1K93A 3BNFA 1LVCA 4XVXA 2XS8A 2ZO5A 4M9AA 4IV6A 4J1VA 1XFZA 2XQRB 3II9A 3MXLA 4H7QA 4DZYA 1IS2A 1XFVA 3D2RA 3Q24A 3VKHA 4JIOA 5K3HA 1Y8NA 2R0MA 3AFEA 3AFFA 2Q8IA 2WBIA 3CE2A 3GQTA 3M9VA 2PNRA 2VR0A 4X28C 1RJ1A 2EBFX 3LG1A 4FF3A 4HKSA 1EGDA 4AI6A 2JIFA 1W07A 2F6LA 4HKRA 2REHA 1SC5A 4Q4UA 2ZDXA 4KSFA 4V25A 3D1IA 3X0YA 3VKGA 1U8VA 1S26A 3BNJA 2BU7A 2FP2A 3R7KA 3MDDA 3Q23A 1FS8A 2A1TA 2DDHA 5B5VA 2BU2A 4P79A 2EBHX 2FONA 4Q17A 4Q1OA 3TTBA 2EC5A 5GJVE 3F29A 5M4KA 4E00A 2JBRA 3MPIA 4L1FA 1RX0A 1XFXA 2Z1QA 2CX9A 4KCFA 3MPJA 4MP2A 4L38A 1EGCA 2IX5A 1X91A 4FF4A 2PG0A 4JEKA 4KS9A 4AKIA 2OEXA 3SF6A 3OIBA 2VF1A 3Q0AA 4O5MA 1K8TA 1OAHA 1GU6A 3SCEA
chains in the Genus database with same CATH topology
3CE2A 4KSAA 2LFWA 4QICA 2EBFX 4FF3A 4AI6A 1Y0VA 4HKSA 2F6LA 4FZ4A 4HKRA 2QR4A 1XFYA 2AO2A 1SC5A 4KSFA 4AKGA 3VKGA 3C2PA 3C46A 3Q0AA 1S26A 4AKHA 2FP2A 2FP1A 1SK6A 3KMLA 3Q23A 2GBBA 3C3LA 4G97A 2EBHX 4P79A 1XFUA 3N0RA 4F0XA 2EC5A 5GJVE 1K90A 1XFWA 2PO4A 1XFXA 1K93A 1RP3A 1LVCA 1XFZA 5GJWE 3Q24A 4FF4A 1PK0A 1XFVA 4KS9A 2AZEA 3X29A 3Q22A 4AKIA 4FF2A 3VKHA 2VF1A 4FF1A 2YGWA 1K8TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GJV E;  4P79 A;  5GJW E;  3X29 A; 
#chains in the Genus database with same CATH topology
 3LGQ A;  2E81 A;  1FS9 A;  5B5W A;  4H81 A;  3BNG A;  2Q8G A;  1UKW A;  3EON A;  3SXQ A;  3TZ2 A;  4FZ4 A;  2QR4 A;  1XFY A;  2AO2 A;  4AKG A;  4IRN A;  3C2P A;  3S7W A;  1EGE A;  5BRK A;  3C46 A;  3P4T A;  2BU5 A;  4KTO A;  4L3X A;  2IX6 A;  2FP1 A;  1GKZ A;  1SK6 A;  1R3B A;  2Q8F A;  3PFD A;  1PI1 A;  2CJ8 A;  1FS7 A;  3NF4 A;  4H85 A;  3D9D A;  5K3G A;  4L3Y A;  2DVL A;  2R0N A;  2YYL A;  3CRK A;  4X28 A;  1RP3 A;  1WS9 A;  2YYM A;  4Q5B A;  3OWA A;  2OT4 A;  2EBA A;  2XS1 A;  2HJN A;  2CJ7 A;  3OWM A;  4JIZ A;  5GJW E;  3CRL A;  1PK0 A;  4ZYJ A;  2AZE A;  3B96 A;  3Q22 A;  2E80 A;  4U83 A;  3TZ0 A;  2YYI A;  3D9G A;  2JBS A;  1R2J A;  4MPE A;  3TZ5 A;  5B6B A;  3X0X A;  2YGW A;  5M4M A;  4FF1 A;  5K3J A;  3RKH A;  1JM6 A;  1Y8O A;  1X90 A;  2OEV A;  4OO2 A;  2BTZ A;  5J71 A;  1SIR A;  2BU8 A;  4QIC A;  3GNC A;  4WJY A;  2ZKJ A;  1Y8P A;  2RDZ A;  2ZDY A;  5M4P A;  2JBT A;  2ZAF A;  3BNH A;  1JQI A;  4V26 A;  3UBR A;  4RM7 A;  1IVH A;  2RFQ A;  3L1T A;  4W9U A;  4ZXV A;  1UDY A;  2OR0 A;  2R03 A;  2RF7 A;  3KML A;  4AKH A;  3D9E A;  4G97 A;  2E0A A;  3D6B A;  1XG2 B;  1XFU A;  4E01 A;  4F0X A;  3HWC A;  4Q5C A;  4G5E A;  3TZ4 A;  5J6A A;  1SIQ A;  3FCJ A;  2C12 A;  2PO4 A;  3TOR A;  3VAD A;  3EOM A;  3MMO A;  3FO3 A;  1GJV A;  1BUC A;  1X8Z A;  4MPN A;  5BRM A;  2CJ6 A;  3X29 A;  2J7A A;  3MKH A;  4FF2 A;  2R05 A;  4LQS B;  3MDE A;  4NXL A;  3GM6 A;  2Q8H A;  2R02 A;  4MP7 A;  4DOY A;  2YYG A;  4KSA A;  2UXW A;  5M4N A;  2LFW A;  2OJQ A;  1Y0V A;  2CJ4 A;  1RJ4 A;  5K3I A;  2YYJ A;  2D29 A;  2YYK A;  4N5F A;  1QDB A;  2C0U A;  4P13 A;  2GBB A;  3D9F A;  3UU9 A;  3SWO A;  4LQQ B;  3C3L A;  1GKX A;  3N0R A;  2VIG A;  1K90 A;  2BU6 A;  1XFW A;  4Q0T A;  2CJ5 A;  4MPC A;  1T9G A;  4L3Z A;  4E02 A;  4HR3 A;  1K93 A;  3BNF A;  1LVC A;  4XVX A;  2XS8 A;  2ZO5 A;  4M9A A;  4IV6 A;  4J1V A;  1XFZ A;  2XQR B;  3II9 A;  3MXL A;  4H7Q A;  4DZY A;  1IS2 A;  1XFV A;  3D2R A;  3Q24 A;  3VKH A;  4JIO A;  5K3H A;  1Y8N A;  2R0M A;  3AFE A;  3AFF A;  2Q8I A;  2WBI A;  3CE2 A;  3GQT A;  3M9V A;  2PNR A;  2VR0 A;  4X28 C;  1RJ1 A;  2EBF X;  3LG1 A;  4FF3 A;  4HKS A;  1EGD A;  4AI6 A;  2JIF A;  1W07 A;  2F6L A;  4HKR A;  2REH A;  1SC5 A;  4Q4U A;  2ZDX A;  4KSF A;  4V25 A;  3D1I A;  3X0Y A;  3VKG A;  1U8V A;  1S26 A;  3BNJ A;  2BU7 A;  2FP2 A;  3R7K A;  3MDD A;  3Q23 A;  1FS8 A;  2A1T A;  2DDH A;  5B5V A;  2BU2 A;  4P79 A;  2EBH X;  2FON A;  4Q17 A;  4Q1O A;  3TTB A;  2EC5 A;  5GJV E;  3F29 A;  5M4K A;  4E00 A;  2JBR A;  3MPI A;  4L1F A;  1RX0 A;  1XFX A;  2Z1Q A;  2CX9 A;  4KCF A;  3MPJ A;  4MP2 A;  4L38 A;  1EGC A;  2IX5 A;  1X91 A;  4FF4 A;  2PG0 A;  4JEK A;  4KS9 A;  4AKI A;  2OEX A;  3SF6 A;  3OIB A;  2VF1 A;  3Q0A A;  4O5M A;  1K8T A;  1OAH A;  1GU6 A;  3SCE A; 
#chains in the Genus database with same CATH homology
 3CE2 A;  4KSA A;  2LFW A;  4QIC A;  2EBF X;  4FF3 A;  4AI6 A;  1Y0V A;  4HKS A;  2F6L A;  4FZ4 A;  4HKR A;  2QR4 A;  1XFY A;  2AO2 A;  1SC5 A;  4KSF A;  4AKG A;  3VKG A;  3C2P A;  3C46 A;  3Q0A A;  1S26 A;  4AKH A;  2FP2 A;  2FP1 A;  1SK6 A;  3KML A;  3Q23 A;  2GBB A;  3C3L A;  4G97 A;  2EBH X;  4P79 A;  1XFU A;  3N0R A;  4F0X A;  2EC5 A;  5GJV E;  1K90 A;  1XFW A;  2PO4 A;  1XFX A;  1K93 A;  1RP3 A;  1LVC A;  1XFZ A;  5GJW E;  3Q24 A;  4FF4 A;  1PK0 A;  1XFV A;  4KS9 A;  2AZE A;  3X29 A;  3Q22 A;  4AKI A;  4FF2 A;  3VKH A;  2VF1 A;  4FF1 A;  2YGW A;  1K8T A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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