4P79A

Crystal structure of mouse claudin-15
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
189
structure length
181
Chain Sequence
SEFMSVAVETFGFFMSALGLLMLGLTLSNSYWRVSTNTIFENLWYSCATDSLGVSNCWDFPSMLALSGYVQGCRALMITAILLGFLGLFLGMVGLRATNVGNMDLSKKAKLLAIAGTLHILAGACGMVAISWYAVNITTDFFNPLYAGTKYELGPALYLGWSASLLSILGGICVFSTAAAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell adhesion
source organism Mus musculus
publication title Crystal structure of a claudin provides insight into the architecture of tight junctions.
pubmed doi rcsb
molecule keywords Claudin-15
total genus 59
structure length 181
sequence length 189
ec nomenclature
pdb deposition date 2014-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00822 PMP22_Claudin PMP-22/EMP/MP20/Claudin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.150 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 4p79A00
4P79A 5GJVE 3X29A 5GJWE
chains in the Genus database with same CATH superfamily
4N5FA 2CJ6A 4E01A 2JBRA 3SCEA 4RM7A 1UDYA 2HJNA 3BNGA 2Q8IA 3OWMA 2EC5A 3LGQA 5B6BA 3VKGA 2OJQA 3GM6A 4WJYA 3PFDA 1SC5A 5J71A 4W9UA 1K8TA 3HWCA 1Y8NA 4DOYA 2WBIA 2RDZA 1GU6A 2R05A 4KSAA 4V25A 3X0XA 3NF4A 3X0YA 4MP7A 2UXWA 5M4MA 3Q24A 1W07A 1XFZA 2FP1A 2EBFX 3C2PA 3VADA 2PNRA 4E00A 4AKGA 2OR0A 3F29A 4L3YA 4JEKA 3X29A 2Q8FA 3D9GA 2YYJA 1PI1A 2R02A 3UBRA 5BRKA 2XS1A 3D1IA 4P79A 1EGCA 1LVCA 2Q8HA 2OEXA 1SIRA 2R0MA 4FF2A 1GJVA 4Q5CA 4LQSB 4FF4A 2Z1QA 1XFWA 4FF3A 2BU8A 1GKZA 3CRKA 1BUCA 1EGDA 3MMOA 3B96A 1U8VA 4Q4UA 1X90A 2E80A 2F6LA 2PO4A 1RJ4A 3MDDA 3TZ0A 2D29A 3UU9A 3AFFA 3Q23A 3TTBA 2C0UA 1SK6A 1GKXA 3OIBA 4X28A 4FF1A 2J7AA 3M9VA 2E0AA 2RF7A 2CJ8A 4ZXVA 4IRNA 5B5WA 3N0RA 2FP2A 1Y8OA 2R0NA 2YYMA 3GQTA 1IS2A 3MDEA 2BU2A 3P4TA 3KMLA 1FS9A 4MPNA 4AI6A 4JIZA 1JQIA 2YYLA 4G5EA 3CRLA 4E02A 4NXLA 4DZYA 5M4NA 2EBAA 1EGEA 3GNCA 4IV6A 2YGWA 4HKSA 3TZ4A 4J1VA 2BU7A 4O5MA 4Q17A 3D6BA 1RJ1A 4KSFA 4V26A 1XFVA 5K3GA 2GBBA 1T9GA 4Q1OA 2DDHA 1Y8PA 2DVLA 2VR0A 3MPIA 5GJVE 2BU5A 2ZDYA 3C46A 1SIQA 2CJ4A 3FO3A 4H81A 1XG2B 2EBHX 2LFWA 2IX5A 4JIOA 3SXQA 1X91A 4LQQB 4FZ4A 5J6AA 1JM6A 2QR4A 2JBSA 2XQRB 2YYGA 2ZDXA 3MPJA 4H85A 4HR3A 2OT4A 5K3HA 2C12A 4G97A 4MP2A 1R3BA 4HKRA 5B5VA 2PG0A 3AFEA 4L38A 4M9AA 3S7WA 2R03A 4ZYJA 3TORA 3TZ2A 2E81A 3D9FA 3MKHA 1Y0VA 2RFQA 3LG1A 3OWAA 2AO2A 4KS9A 5K3JA 3R7KA 2OEVA 4Q5BA 3C3LA 4KTOA 4OO2A 2IX6A 3EONA 2ZO5A 2Q8GA 4QICA 2CJ5A 5M4KA 3RKHA 4L3ZA 3D9DA 2XS8A 1UKWA 1XFYA 2BTZA 4AKHA 3MXLA 4U83A 2JBTA 3BNJA 1PK0A 1K90A 4F0XA 2ZAFA 4Q0TA 5BRMA 1FS7A 4L1FA 4P13A 1OAHA 3BNHA 4XVXA 4AKIA 1RP3A 2CX9A 3CE2A 3II9A 2VF1A 4MPEA 5K3IA 2AZEA 3D9EA 1S26A 1WS9A 2JIFA 2BU6A 4MPCA 4X28C 2CJ7A 2YYKA 3SWOA 4KCFA 1R2JA 1XFUA 1K93A 2YYIA 5GJWE 3Q0AA 3Q22A 3VKHA 2ZKJA 2VIGA 4L3XA 2REHA 3TZ5A 1X8ZA 1FS8A 5M4PA 1QDBA 1RX0A 1IVHA 2FONA 3D2RA 3L1TA 1XFXA 4H7QA 3SF6A 3FCJA 2A1TA 3BNFA 3EOMA
chains in the Genus database with same CATH topology
1XFVA 2GBBA 2PO4A 1XFYA 2F6LA 2EC5A 5GJVE 3C46A 4AKHA 2EBHX 3VKGA 3Q23A 1PK0A 2LFWA 1K90A 1SK6A 4F0XA 4FF1A 1SC5A 4AKIA 1K8TA 1RP3A 4FZ4A 3CE2A 2QR4A 2VF1A 4KSAA 3N0RA 2AZEA 2FP2A 3Q24A 1S26A 4G97A 1XFZA 2FP1A 3KMLA 2EBFX 4HKRA 3C2PA 3Q0AA 4AI6A 4AKGA 5GJWE 1XFUA 1K93A 3Q22A 3VKHA 3X29A 1Y0VA 4P79A 1LVCA 2AO2A 4KS9A 4FF2A 1XFXA 3C3LA 4FF4A 2YGWA 4HKSA 1XFWA 4FF3A 4KSFA 4QICA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P79 A;  5GJV E;  3X29 A;  5GJW E; 
#chains in the Genus database with same CATH topology
 4N5F A;  2CJ6 A;  4E01 A;  2JBR A;  3SCE A;  4RM7 A;  1UDY A;  2HJN A;  3BNG A;  2Q8I A;  3OWM A;  2EC5 A;  3LGQ A;  5B6B A;  3VKG A;  2OJQ A;  3GM6 A;  4WJY A;  3PFD A;  1SC5 A;  5J71 A;  4W9U A;  1K8T A;  3HWC A;  1Y8N A;  4DOY A;  2WBI A;  2RDZ A;  1GU6 A;  2R05 A;  4KSA A;  4V25 A;  3X0X A;  3NF4 A;  3X0Y A;  4MP7 A;  2UXW A;  5M4M A;  3Q24 A;  1W07 A;  1XFZ A;  2FP1 A;  2EBF X;  3C2P A;  3VAD A;  2PNR A;  4E00 A;  4AKG A;  2OR0 A;  3F29 A;  4L3Y A;  4JEK A;  3X29 A;  2Q8F A;  3D9G A;  2YYJ A;  1PI1 A;  2R02 A;  3UBR A;  5BRK A;  2XS1 A;  3D1I A;  4P79 A;  1EGC A;  1LVC A;  2Q8H A;  2OEX A;  1SIR A;  2R0M A;  4FF2 A;  1GJV A;  4Q5C A;  4LQS B;  4FF4 A;  2Z1Q A;  1XFW A;  4FF3 A;  2BU8 A;  1GKZ A;  3CRK A;  1BUC A;  1EGD A;  3MMO A;  3B96 A;  1U8V A;  4Q4U A;  1X90 A;  2E80 A;  2F6L A;  2PO4 A;  1RJ4 A;  3MDD A;  3TZ0 A;  2D29 A;  3UU9 A;  3AFF A;  3Q23 A;  3TTB A;  2C0U A;  1SK6 A;  1GKX A;  3OIB A;  4X28 A;  4FF1 A;  2J7A A;  3M9V A;  2E0A A;  2RF7 A;  2CJ8 A;  4ZXV A;  4IRN A;  5B5W A;  3N0R A;  2FP2 A;  1Y8O A;  2R0N A;  2YYM A;  3GQT A;  1IS2 A;  3MDE A;  2BU2 A;  3P4T A;  3KML A;  1FS9 A;  4MPN A;  4AI6 A;  4JIZ A;  1JQI A;  2YYL A;  4G5E A;  3CRL A;  4E02 A;  4NXL A;  4DZY A;  5M4N A;  2EBA A;  1EGE A;  3GNC A;  4IV6 A;  2YGW A;  4HKS A;  3TZ4 A;  4J1V A;  2BU7 A;  4O5M A;  4Q17 A;  3D6B A;  1RJ1 A;  4KSF A;  4V26 A;  1XFV A;  5K3G A;  2GBB A;  1T9G A;  4Q1O A;  2DDH A;  1Y8P A;  2DVL A;  2VR0 A;  3MPI A;  5GJV E;  2BU5 A;  2ZDY A;  3C46 A;  1SIQ A;  2CJ4 A;  3FO3 A;  4H81 A;  1XG2 B;  2EBH X;  2LFW A;  2IX5 A;  4JIO A;  3SXQ A;  1X91 A;  4LQQ B;  4FZ4 A;  5J6A A;  1JM6 A;  2QR4 A;  2JBS A;  2XQR B;  2YYG A;  2ZDX A;  3MPJ A;  4H85 A;  4HR3 A;  2OT4 A;  5K3H A;  2C12 A;  4G97 A;  4MP2 A;  1R3B A;  4HKR A;  5B5V A;  2PG0 A;  3AFE A;  4L38 A;  4M9A A;  3S7W A;  2R03 A;  4ZYJ A;  3TOR A;  3TZ2 A;  2E81 A;  3D9F A;  3MKH A;  1Y0V A;  2RFQ A;  3LG1 A;  3OWA A;  2AO2 A;  4KS9 A;  5K3J A;  3R7K A;  2OEV A;  4Q5B A;  3C3L A;  4KTO A;  4OO2 A;  2IX6 A;  3EON A;  2ZO5 A;  2Q8G A;  4QIC A;  2CJ5 A;  5M4K A;  3RKH A;  4L3Z A;  3D9D A;  2XS8 A;  1UKW A;  1XFY A;  2BTZ A;  4AKH A;  3MXL A;  4U83 A;  2JBT A;  3BNJ A;  1PK0 A;  1K90 A;  4F0X A;  2ZAF A;  4Q0T A;  5BRM A;  1FS7 A;  4L1F A;  4P13 A;  1OAH A;  3BNH A;  4XVX A;  4AKI A;  1RP3 A;  2CX9 A;  3CE2 A;  3II9 A;  2VF1 A;  4MPE A;  5K3I A;  2AZE A;  3D9E A;  1S26 A;  1WS9 A;  2JIF A;  2BU6 A;  4MPC A;  4X28 C;  2CJ7 A;  2YYK A;  3SWO A;  4KCF A;  1R2J A;  1XFU A;  1K93 A;  2YYI A;  5GJW E;  3Q0A A;  3Q22 A;  3VKH A;  2ZKJ A;  2VIG A;  4L3X A;  2REH A;  3TZ5 A;  1X8Z A;  1FS8 A;  5M4P A;  1QDB A;  1RX0 A;  1IVH A;  2FON A;  3D2R A;  3L1T A;  1XFX A;  4H7Q A;  3SF6 A;  3FCJ A;  2A1T A;  3BNF A;  3EOM A; 
#chains in the Genus database with same CATH homology
 1XFV A;  2GBB A;  2PO4 A;  1XFY A;  2F6L A;  2EC5 A;  5GJV E;  3C46 A;  4AKH A;  2EBH X;  3VKG A;  3Q23 A;  1PK0 A;  2LFW A;  1K90 A;  1SK6 A;  4F0X A;  4FF1 A;  1SC5 A;  4AKI A;  1K8T A;  1RP3 A;  4FZ4 A;  3CE2 A;  2QR4 A;  2VF1 A;  4KSA A;  3N0R A;  2AZE A;  2FP2 A;  3Q24 A;  1S26 A;  4G97 A;  1XFZ A;  2FP1 A;  3KML A;  2EBF X;  4HKR A;  3C2P A;  3Q0A A;  4AI6 A;  4AKG A;  5GJW E;  1XFU A;  1K93 A;  3Q22 A;  3VKH A;  3X29 A;  1Y0V A;  4P79 A;  1LVC A;  2AO2 A;  4KS9 A;  4FF2 A;  1XFX A;  3C3L A;  4FF4 A;  2YGW A;  4HKS A;  1XFW A;  4FF3 A;  4KSF A;  4QIC A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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