4HKRA

Calcium release-activated calcium (crac) channel orai
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
191
structure length
165
Chain Sequence
TYLSWRKLQLSRAKLKASSKTSALLSGFAMVAMVEVQMLIAFAICTTLLVAVHMLALMISTCILPNPHERLHWYIETAWAFSTLLGLILFLLEIAILCWVKFYDLSRRAAWSATVVLIPVMIIFMAFAIHFYRSLVSHKYEVTVSGIRELEMLKEQMEQDHLEHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the calcium release-activated calcium channel Orai.
pubmed doi rcsb
molecule tags Transport protein
source organism Drosophila melanogaster
molecule keywords Calcium release-activated calcium channel protein 1
total genus 69
structure length 165
sequence length 191
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07856 Orai-1 Mediator of CRAC channel activity
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.140 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A; domain 3 4hkrA00
4HKSA 4HKRA
chains in the Genus database with same CATH superfamily
3N0RA 3TZ0A 4Q17A 3GNCA 3Q0AA 1PK0A 4MP7A 4L3XA 1T9GA 1GKXA 2ZO5A 3MDEA 4N5FA 3R7KA 3GM6A 1FS8A 4H85A 2Q8FA 4L38A 3BNFA 3TORA 3EONA 2ZAFA 2RF7A 2Q8GA 2R02A 1PI1A 2PNRA 5M4PA 3LGQA 4L3YA 1JM6A 2ZKJA 4LQSB 3TTBA 1OAHA 1IVHA 1XFXA 3MPJA 3BNHA 3M9VA 4WJYA 3RKHA 3CRLA 3UU9A 5GJWE 2CX9A 3VKGA 1SC5A 2IX5A 3VKHA 5B6BA 1SIQA 4HR3A 2QR4A 2D29A 5K3HA 3C2PA 4KSAA 3D9DA 1RJ4A 3FCJA 4RM7A 3BNGA 2ZDYA 5K3IA 3SXQA 2RDZA 1LVCA 3P4TA 2EBHX 3OWMA 2OT4A 2ZDXA 3GQTA 1XFYA 1GJVA 2YYGA 3L1TA 2BTZA 2DDHA 2E81A 5B5WA 5J71A 2F6LA 2R05A 1WS9A 2R0MA 2LFWA 3D9FA 3UBRA 2DVLA 2FP2A 3MPIA 5GJVE 3SWOA 2YYKA 4KCFA 3AFEA 4V25A 3Q22A 2YYJA 3S7WA 3SCEA 1X91A 2Q8HA 1X8ZA 3TZ4A 4Q1OA 5M4MA 4IV6A 4X28C 4MPEA 2R03A 4U83A 2FP1A 4P13A 4ZXVA 2OR0A 1IS2A 1RP3A 4FZ4A 1K93A 1X90A 2BU6A 3B96A 3OIBA 1K8TA 1EGCA 2C0UA 2REHA 5M4KA 1R3BA 2BU8A 3NF4A 2YYMA 4QICA 4M9AA 1RX0A 2JBTA 5BRKA 5J6AA 4AKGA 5B5VA 2AZEA 2JBSA 4XVXA 2JIFA 3LG1A 2YGWA 2Z1QA 2VF1A 4H81A 4Q5CA 4L1FA 4AKHA 3EOMA 3TZ5A 1JQIA 3CE2A 1W07A 2PO4A 4HKSA 3C46A 2XQRB 4HKRA 2UXWA 3X0XA 3VADA 2BU7A 3Q24A 1UKWA 4MPCA 2R0NA 3TZ2A 4FF4A 1Y8OA 1SK6A 2IX6A 2YYIA 3D1IA 1EGDA 4JIZA 4G97A 1K90A 1U8VA 2BU5A 2EC5A 3FO3A 4H7QA 4J1VA 4JEKA 2CJ7A 2EBAA 3BNJA 4Q4UA 4DZYA 2J7AA 3Q23A 3OWAA 1FS7A 1XFWA 1QDBA 4JIOA 4E02A 4V26A 4MP2A 2WBIA 3X0YA 1BUCA 1SIRA 2FONA 4W9UA 2JBRA 2CJ8A 2PG0A 3MMOA 2EBFX 4E00A 1GU6A 2CJ6A 4FF3A 4MPNA 4FF2A 3PFDA 1UDYA 2YYLA 1FS9A 2XS1A 2OEXA 1XFUA 3D2RA 4LQQB 5K3JA 4AKIA 2Q8IA 2XS8A 1R2JA 1XFZA 2C12A 2E0AA 2OJQA 2BU2A 2OEVA 1S26A 4KS9A 4X28A 4F0XA 4Q0TA 3D9GA 4AI6A 3MDDA 3F29A 4ZYJA 2A1TA 3CRKA 5BRMA 4E01A 3MXLA 3AFFA 4NXLA 4KSFA 4O5MA 2GBBA 1Y8PA 3C3LA 1Y8NA 4Q5BA 4IRNA 2HJNA 3MKHA 2VR0A 4L3ZA 4OO2A 1Y0VA 3SF6A 4DOYA 1RJ1A 3D6BA 1GKZA 1XFVA 4G5EA 4P79A 3X29A 2CJ5A 2CJ4A 4FF1A 2AO2A 3D9EA 1EGEA 5M4NA 2E80A 2RFQA 3II9A 4KTOA 3HWCA 1XG2B 5K3GA 2VIGA 3KMLA
chains in the Genus database with same CATH topology
3N0RA 2EBHX 2AZEA 3Q0AA 1PK0A 1XFYA 1XFUA 4AKIA 2YGWA 2VF1A 4AKHA 2F6LA 1XFZA 3CE2A 2LFWA 4FF2A 2PO4A 4HKSA 1S26A 4KS9A 2FP2A 4F0XA 3C46A 4AI6A 4HKRA 5GJVE 3Q24A 3Q22A 4FF4A 1SK6A 4KSFA 2GBBA 3C3LA 1XFXA 4G97A 1K90A 2EC5A 5GJWE 3VKGA 1Y0VA 3Q23A 2FP1A 1SC5A 1XFWA 1RP3A 4FZ4A 3VKHA 1K93A 1XFVA 2QR4A 4P79A 3X29A 3C2PA 2AO2A 1K8TA 4FF1A 4KSAA 4FF3A 2EBFX 4QICA 4AKGA 3KMLA 1LVCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HKS A;  4HKR A; 
#chains in the Genus database with same CATH topology
 3N0R A;  3TZ0 A;  4Q17 A;  3GNC A;  3Q0A A;  1PK0 A;  4MP7 A;  4L3X A;  1T9G A;  1GKX A;  2ZO5 A;  3MDE A;  4N5F A;  3R7K A;  3GM6 A;  1FS8 A;  4H85 A;  2Q8F A;  4L38 A;  3BNF A;  3TOR A;  3EON A;  2ZAF A;  2RF7 A;  2Q8G A;  2R02 A;  1PI1 A;  2PNR A;  5M4P A;  3LGQ A;  4L3Y A;  1JM6 A;  2ZKJ A;  4LQS B;  3TTB A;  1OAH A;  1IVH A;  1XFX A;  3MPJ A;  3BNH A;  3M9V A;  4WJY A;  3RKH A;  3CRL A;  3UU9 A;  5GJW E;  2CX9 A;  3VKG A;  1SC5 A;  2IX5 A;  3VKH A;  5B6B A;  1SIQ A;  4HR3 A;  2QR4 A;  2D29 A;  5K3H A;  3C2P A;  4KSA A;  3D9D A;  1RJ4 A;  3FCJ A;  4RM7 A;  3BNG A;  2ZDY A;  5K3I A;  3SXQ A;  2RDZ A;  1LVC A;  3P4T A;  2EBH X;  3OWM A;  2OT4 A;  2ZDX A;  3GQT A;  1XFY A;  1GJV A;  2YYG A;  3L1T A;  2BTZ A;  2DDH A;  2E81 A;  5B5W A;  5J71 A;  2F6L A;  2R05 A;  1WS9 A;  2R0M A;  2LFW A;  3D9F A;  3UBR A;  2DVL A;  2FP2 A;  3MPI A;  5GJV E;  3SWO A;  2YYK A;  4KCF A;  3AFE A;  4V25 A;  3Q22 A;  2YYJ A;  3S7W A;  3SCE A;  1X91 A;  2Q8H A;  1X8Z A;  3TZ4 A;  4Q1O A;  5M4M A;  4IV6 A;  4X28 C;  4MPE A;  2R03 A;  4U83 A;  2FP1 A;  4P13 A;  4ZXV A;  2OR0 A;  1IS2 A;  1RP3 A;  4FZ4 A;  1K93 A;  1X90 A;  2BU6 A;  3B96 A;  3OIB A;  1K8T A;  1EGC A;  2C0U A;  2REH A;  5M4K A;  1R3B A;  2BU8 A;  3NF4 A;  2YYM A;  4QIC A;  4M9A A;  1RX0 A;  2JBT A;  5BRK A;  5J6A A;  4AKG A;  5B5V A;  2AZE A;  2JBS A;  4XVX A;  2JIF A;  3LG1 A;  2YGW A;  2Z1Q A;  2VF1 A;  4H81 A;  4Q5C A;  4L1F A;  4AKH A;  3EOM A;  3TZ5 A;  1JQI A;  3CE2 A;  1W07 A;  2PO4 A;  4HKS A;  3C46 A;  2XQR B;  4HKR A;  2UXW A;  3X0X A;  3VAD A;  2BU7 A;  3Q24 A;  1UKW A;  4MPC A;  2R0N A;  3TZ2 A;  4FF4 A;  1Y8O A;  1SK6 A;  2IX6 A;  2YYI A;  3D1I A;  1EGD A;  4JIZ A;  4G97 A;  1K90 A;  1U8V A;  2BU5 A;  2EC5 A;  3FO3 A;  4H7Q A;  4J1V A;  4JEK A;  2CJ7 A;  2EBA A;  3BNJ A;  4Q4U A;  4DZY A;  2J7A A;  3Q23 A;  3OWA A;  1FS7 A;  1XFW A;  1QDB A;  4JIO A;  4E02 A;  4V26 A;  4MP2 A;  2WBI A;  3X0Y A;  1BUC A;  1SIR A;  2FON A;  4W9U A;  2JBR A;  2CJ8 A;  2PG0 A;  3MMO A;  2EBF X;  4E00 A;  1GU6 A;  2CJ6 A;  4FF3 A;  4MPN A;  4FF2 A;  3PFD A;  1UDY A;  2YYL A;  1FS9 A;  2XS1 A;  2OEX A;  1XFU A;  3D2R A;  4LQQ B;  5K3J A;  4AKI A;  2Q8I A;  2XS8 A;  1R2J A;  1XFZ A;  2C12 A;  2E0A A;  2OJQ A;  2BU2 A;  2OEV A;  1S26 A;  4KS9 A;  4X28 A;  4F0X A;  4Q0T A;  3D9G A;  4AI6 A;  3MDD A;  3F29 A;  4ZYJ A;  2A1T A;  3CRK A;  5BRM A;  4E01 A;  3MXL A;  3AFF A;  4NXL A;  4KSF A;  4O5M A;  2GBB A;  1Y8P A;  3C3L A;  1Y8N A;  4Q5B A;  4IRN A;  2HJN A;  3MKH A;  2VR0 A;  4L3Z A;  4OO2 A;  1Y0V A;  3SF6 A;  4DOY A;  1RJ1 A;  3D6B A;  1GKZ A;  1XFV A;  4G5E A;  4P79 A;  3X29 A;  2CJ5 A;  2CJ4 A;  4FF1 A;  2AO2 A;  3D9E A;  1EGE A;  5M4N A;  2E80 A;  2RFQ A;  3II9 A;  4KTO A;  3HWC A;  1XG2 B;  5K3G A;  2VIG A;  3KML A; 
#chains in the Genus database with same CATH homology
 3N0R A;  2EBH X;  2AZE A;  3Q0A A;  1PK0 A;  1XFY A;  1XFU A;  4AKI A;  2YGW A;  2VF1 A;  4AKH A;  2F6L A;  1XFZ A;  3CE2 A;  2LFW A;  4FF2 A;  2PO4 A;  4HKS A;  1S26 A;  4KS9 A;  2FP2 A;  4F0X A;  3C46 A;  4AI6 A;  4HKR A;  5GJV E;  3Q24 A;  3Q22 A;  4FF4 A;  1SK6 A;  4KSF A;  2GBB A;  3C3L A;  1XFX A;  4G97 A;  1K90 A;  2EC5 A;  5GJW E;  3VKG A;  1Y0V A;  3Q23 A;  2FP1 A;  1SC5 A;  1XFW A;  1RP3 A;  4FZ4 A;  3VKH A;  1K93 A;  1XFV A;  2QR4 A;  4P79 A;  3X29 A;  3C2P A;  2AO2 A;  1K8T A;  4FF1 A;  4KSA A;  4FF3 A;  2EBF X;  4QIC A;  4AKG A;  3KML A;  1LVC A; 
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