4OO2A

Streptomyces globisporus c-1027 fad dependent (s)-3-chloro-β-tyrosine-s-sgcc2 c-5 hydroxylase sgcc apo form
Total Genus 170
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
170
sequence length
510
structure length
506
Chain Sequence
TRPLTGEEYLESLRDAREVYLDGSRVKDVTAHPAFHNPARMTARLYDSLHDPAQKAVLTAPTDAGDGFTHRFFTAPRSVDDLVKDQAAIASWARKSYGWMGRSPDYKASFLGTLGANADFYEPFADNARRWYRESQEKVLYWNHAFLHPPVDRSEVGDVFIHVERETDAGLVVSGAKVVATGSALTHAAFISHWGLPIKDRKFALVATVPMDADGLKVICRPSYSANAATTGSPFDNPLSSRLDENDAILVLDQVLIPWENVFVYGNLGKVHLLAGQSGMIERATFHGCTRLAVKLEFIAGLLAKALDITGAKDFRGVQTRLGEVLAWRNLFWSLSDAAARNPVPWKNGTLLPNPQAGMAYRWFMQIGYPRVLEIVQQDVASGLMYVNSSTEDFRNPETGPYLEKYLRGSDGAGAVERVKVMKLLWDAVGSDFGGRHELYERNYSGNHENTRIELLLSQTASGKLDSYMDFAQACMDEYDLDGWTAPDLESFHAMRSASRDLLGGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structures of SgcE6 and SgcC, the Two-Component Monooxygenase That Catalyzes Hydroxylation of a Carrier Protein-Tethered Substrate during the Biosynthesis of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Streptomyces globisporus
molecule keywords Chlorophenol-4-monooxygenase
total genus 170
structure length 506
sequence length 510
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-01-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03241 HpaB 4-hydroxyphenylacetate 3-hydroxylase C terminal
A PF11794 HpaB_N 4-hydroxyphenylacetate 3-hydroxylase N terminal
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 4oo2A02
3MPJA 3EONA 4OO2A 2FONA 4ZXVA 4ZYJA 3SCEA 1EGDA 2RDZA 2CX9A 2PG0A 4KCFA 1R2JA 2EBAA 2YYGA 2JBTA 3GNCA 3MXLA 2IX6A 4M9AA 2JBSA 2C0UA 1QDBA 3D6BA 1GU6A 4L3YA 4U83A 4Q0TA 3L1TA 5K3GA 3SWOA 2ZO5A 3BNGA 3B96A 1IS2A 2RF7A 4KTOA 4X28C 3SXQA 1W07A 2OT4A 4G5EA 3TORA 1OAHA 3OWAA 2C12A 2DDHA 2RFQA 2E81A 3MPIA 3GM6A 3MDDA 3UU9A 3D9FA 4Q1OA 2YYMA 1EGCA 3BNFA 3FCJA 3EOMA 1UKWA 3AFEA 4L3XA 2UXWA 3X0XA 3D9EA 2ZAFA 4IV6A 2DVLA 4W9UA 2YYJA 3MMOA 2R0NA 1IVHA 3FO3A 3X0YA 4P13A 3BNJA 3LGQA 1SIRA 5K3JA 4L38A 4WJYA 1FS7A 3RKHA 3R7KA 5K3IA 3OIBA 4HR3A 1JQIA 2VR0A 3HWCA 1RX0A 3NF4A 3D1IA 2YYLA 3LG1A 4L1FA 5K3HA 4DOYA 4Q5BA 4IRNA 3PFDA 1WS9A 3AFFA 3MDEA 3UBRA 2E80A 4O5MA 4L3ZA 3S7WA 2A1TA 2R0MA 2J7AA 3SF6A 2WBIA 3OWMA 3D9GA 3F29A 3M9VA 1FS8A 4X28A 2Z1QA 3GQTA 4N5FA 3TTBA 1BUCA 2REHA 3MKHA 4XVXA 1EGEA 4NXLA 1FS9A 1T9GA 3BNHA 4JEKA 3II9A 1SIQA 2IX5A 3P4TA 3D9DA 4Q5CA 2YYKA 2JBRA 2YYIA 2D29A 4RM7A 4Q17A 4Q4UA 1UDYA 2JIFA 2OR0A 1U8VA 2VIGA
chains in the Genus database with same CATH superfamily
4AKHA 1LVCA 2GBBA 3CRLA 3MPJA 3EONA 4OO2A 2FONA 1RP3A 4ZXVA 4ZYJA 3SCEA 5M4KA 1EGDA 2RDZA 2CX9A 2PG0A 4KCFA 3Q23A 1R2JA 3C2PA 5B6BA 2EBAA 4H85A 2YYGA 2JBTA 4FF4A 3GNCA 3N0RA 4LQQB 3MXLA 2IX6A 4M9AA 2Q8GA 2JBSA 2C0UA 1QDBA 2CJ8A 3D6BA 5BRMA 1GU6A 4H81A 4L3YA 4E00A 2R03A 4LQSB 4Q0TA 4U83A 5BRKA 3L1TA 5K3GA 3VADA 3SWOA 3TZ2A 3C46A 3VKGA 2ZO5A 2OEXA 4E01A 3BNGA 4P79A 3B96A 1IS2A 4JIZA 2BU5A 2BTZA 2RF7A 4KTOA 4X28C 4HKSA 3SXQA 1W07A 2OT4A 4G5EA 1X90A 3Q0AA 1XFXA 3TORA 3Q22A 1OAHA 3OWAA 2C12A 2DDHA 2RFQA 4V25A 2E81A 3TZ0A 4KS9A 1XG2B 4G97A 3MPIA 3GM6A 3MDDA 3UU9A 3D9FA 4Q1OA 2EBFX 4MPEA 4FF3A 2YYMA 1EGCA 3BNFA 3FCJA 2FP1A 3EOMA 5M4PA 1UKWA 1XFZA 2BU2A 3AFEA 4L3XA 2ZKJA 4KSAA 4MP7A 2UXWA 3X0XA 2ZDXA 1SK6A 2Q8HA 3D9EA 2ZAFA 4IV6A 2DVLA 3CRKA 4H7QA 1JM6A 4J1VA 4W9UA 4E02A 1XFWA 2YYJA 1Y8OA 1RJ1A 3MMOA 2R0NA 1IVHA 2EC5A 3FO3A 3CE2A 3KMLA 4P13A 3X0YA 2XS8A 1SC5A 1XFYA 2ZDYA 3BNJA 3LGQA 4V26A 4F0XA 1SIRA 2LFWA 5K3JA 2VF1A 4L38A 1GJVA 1FS7A 4WJYA 3RKHA 3R7KA 5K3IA 2Q8FA 3OIBA 2CJ7A 2R05A 2XS1A 1JQIA 4HR3A 3D2RA 2VR0A 1XFUA 1RX0A 3HWCA 3NF4A 4AKIA 3D1IA 3TZ4A 5GJVE 2EBHX 2YGWA 1R3BA 2YYLA 4FF2A 3LG1A 4L1FA 5K3HA 2FP2A 4DOYA 4Q5BA 4FZ4A 1K90A 4IRNA 2PNRA 5M4NA 1Y8NA 3PFDA 1WS9A 3AFFA 3MDEA 3UBRA 2E0AA 2E80A 4MP2A 1X8ZA 1XFVA 4O5MA 4L3ZA 3S7WA 2A1TA 2CJ5A 2R0MA 2J7AA 3X29A 3SF6A 2WBIA 4DZYA 3OWMA 5J71A 3D9GA 3F29A 3M9VA 1FS8A 1Y8PA 4X28A 2R02A 3VKHA 1GKXA 2Z1QA 3Q24A 3GQTA 4N5FA 5M4MA 1X91A 2F6LA 1PI1A 2OEVA 2HJNA 5B5VA 4AI6A 3C3LA 1K8TA 4HKRA 2BU8A 1BUCA 1Y0VA 2REHA 3MKHA 4XVXA 3TTBA 1EGEA 1PK0A 2CJ6A 5J6AA 2BU6A 4NXLA 1FS9A 1S26A 1T9GA 3BNHA 4JEKA 2PO4A 2Q8IA 3II9A 1RJ4A 1SIQA 2IX5A 3P4TA 3D9DA 1GKZA 4JIOA 4MPNA 4Q5CA 2BU7A 2JBRA 2YYKA 2YYIA 3TZ5A 2OJQA 2AO2A 2D29A 2XQRB 4RM7A 2AZEA 4FF1A 4Q17A 4MPCA 4Q4UA 5B5WA 5GJWE 1UDYA 2JIFA 2OR0A 4AKGA 4KSFA 2QR4A 1U8VA 1K93A 2VIGA 4QICA 2CJ4A
chains in the Genus database with same CATH topology
3MPJA 3EONA 4OO2A 2FONA 4ZXVA 4ZYJA 3SCEA 1EGDA 2RDZA 2CX9A 2PG0A 4KCFA 1R2JA 2EBAA 2YYGA 2JBTA 3GNCA 3MXLA 2IX6A 4M9AA 2JBSA 2C0UA 1QDBA 3D6BA 1GU6A 4L3YA 4U83A 4Q0TA 3L1TA 5K3GA 3SWOA 2ZO5A 3BNGA 3B96A 1IS2A 2RF7A 4KTOA 4X28C 3SXQA 1W07A 2OT4A 4G5EA 3TORA 1OAHA 3OWAA 2C12A 2DDHA 2RFQA 2E81A 3MPIA 3GM6A 3MDDA 3UU9A 3D9FA 4Q1OA 2YYMA 1EGCA 3BNFA 3FCJA 3EOMA 1UKWA 3AFEA 4L3XA 2UXWA 3X0XA 3D9EA 2ZAFA 4IV6A 2DVLA 4W9UA 2YYJA 3MMOA 2R0NA 1IVHA 3FO3A 3X0YA 4P13A 3BNJA 3LGQA 1SIRA 5K3JA 4L38A 4WJYA 1FS7A 3RKHA 3R7KA 5K3IA 3OIBA 4HR3A 1JQIA 2VR0A 3HWCA 1RX0A 3NF4A 3D1IA 2YYLA 3LG1A 4L1FA 5K3HA 4DOYA 4Q5BA 4IRNA 3PFDA 1WS9A 3AFFA 3MDEA 3UBRA 2E80A 4O5MA 4L3ZA 3S7WA 2A1TA 2R0MA 2J7AA 3SF6A 2WBIA 3OWMA 3D9GA 3F29A 3M9VA 1FS8A 4X28A 2Z1QA 3GQTA 4N5FA 3TTBA 1BUCA 2REHA 3MKHA 4XVXA 1EGEA 4NXLA 1FS9A 1T9GA 3BNHA 4JEKA 3II9A 1SIQA 2IX5A 3P4TA 3D9DA 4Q5CA 2YYKA 2JBRA 2YYIA 2D29A 4RM7A 4Q17A 4Q4UA 1UDYA 2JIFA 2OR0A 1U8VA 2VIGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MPJ A;  3EON A;  4OO2 A;  2FON A;  4ZXV A;  4ZYJ A;  3SCE A;  1EGD A;  2RDZ A;  2CX9 A;  2PG0 A;  4KCF A;  1R2J A;  2EBA A;  2YYG A;  2JBT A;  3GNC A;  3MXL A;  2IX6 A;  4M9A A;  2JBS A;  2C0U A;  1QDB A;  3D6B A;  1GU6 A;  4L3Y A;  4U83 A;  4Q0T A;  3L1T A;  5K3G A;  3SWO A;  2ZO5 A;  3BNG A;  3B96 A;  1IS2 A;  2RF7 A;  4KTO A;  4X28 C;  3SXQ A;  1W07 A;  2OT4 A;  4G5E A;  3TOR A;  1OAH A;  3OWA A;  2C12 A;  2DDH A;  2RFQ A;  2E81 A;  3MPI A;  3GM6 A;  3MDD A;  3UU9 A;  3D9F A;  4Q1O A;  2YYM A;  1EGC A;  3BNF A;  3FCJ A;  3EOM A;  1UKW A;  3AFE A;  4L3X A;  2UXW A;  3X0X A;  3D9E A;  2ZAF A;  4IV6 A;  2DVL A;  4W9U A;  2YYJ A;  3MMO A;  2R0N A;  1IVH A;  3FO3 A;  3X0Y A;  4P13 A;  3BNJ A;  3LGQ A;  1SIR A;  5K3J A;  4L38 A;  4WJY A;  1FS7 A;  3RKH A;  3R7K A;  5K3I A;  3OIB A;  4HR3 A;  1JQI A;  2VR0 A;  3HWC A;  1RX0 A;  3NF4 A;  3D1I A;  2YYL A;  3LG1 A;  4L1F A;  5K3H A;  4DOY A;  4Q5B A;  4IRN A;  3PFD A;  1WS9 A;  3AFF A;  3MDE A;  3UBR A;  2E80 A;  4O5M A;  4L3Z A;  3S7W A;  2A1T A;  2R0M A;  2J7A A;  3SF6 A;  2WBI A;  3OWM A;  3D9G A;  3F29 A;  3M9V A;  1FS8 A;  4X28 A;  2Z1Q A;  3GQT A;  4N5F A;  3TTB A;  1BUC A;  2REH A;  3MKH A;  4XVX A;  1EGE A;  4NXL A;  1FS9 A;  1T9G A;  3BNH A;  4JEK A;  3II9 A;  1SIQ A;  2IX5 A;  3P4T A;  3D9D A;  4Q5C A;  2YYK A;  2JBR A;  2YYI A;  2D29 A;  4RM7 A;  4Q17 A;  4Q4U A;  1UDY A;  2JIF A;  2OR0 A;  1U8V A;  2VIG A; 
#chains in the Genus database with same CATH topology
 4AKH A;  1LVC A;  2GBB A;  3CRL A;  3MPJ A;  3EON A;  4OO2 A;  2FON A;  1RP3 A;  4ZXV A;  4ZYJ A;  3SCE A;  5M4K A;  1EGD A;  2RDZ A;  2CX9 A;  2PG0 A;  4KCF A;  3Q23 A;  1R2J A;  3C2P A;  5B6B A;  2EBA A;  4H85 A;  2YYG A;  2JBT A;  4FF4 A;  3GNC A;  3N0R A;  4LQQ B;  3MXL A;  2IX6 A;  4M9A A;  2Q8G A;  2JBS A;  2C0U A;  1QDB A;  2CJ8 A;  3D6B A;  5BRM A;  1GU6 A;  4H81 A;  4L3Y A;  4E00 A;  2R03 A;  4LQS B;  4Q0T A;  4U83 A;  5BRK A;  3L1T A;  5K3G A;  3VAD A;  3SWO A;  3TZ2 A;  3C46 A;  3VKG A;  2ZO5 A;  2OEX A;  4E01 A;  3BNG A;  4P79 A;  3B96 A;  1IS2 A;  4JIZ A;  2BU5 A;  2BTZ A;  2RF7 A;  4KTO A;  4X28 C;  4HKS A;  3SXQ A;  1W07 A;  2OT4 A;  4G5E A;  1X90 A;  3Q0A A;  1XFX A;  3TOR A;  3Q22 A;  1OAH A;  3OWA A;  2C12 A;  2DDH A;  2RFQ A;  4V25 A;  2E81 A;  3TZ0 A;  4KS9 A;  1XG2 B;  4G97 A;  3MPI A;  3GM6 A;  3MDD A;  3UU9 A;  3D9F A;  4Q1O A;  2EBF X;  4MPE A;  4FF3 A;  2YYM A;  1EGC A;  3BNF A;  3FCJ A;  2FP1 A;  3EOM A;  5M4P A;  1UKW A;  1XFZ A;  2BU2 A;  3AFE A;  4L3X A;  2ZKJ A;  4KSA A;  4MP7 A;  2UXW A;  3X0X A;  2ZDX A;  1SK6 A;  2Q8H A;  3D9E A;  2ZAF A;  4IV6 A;  2DVL A;  3CRK A;  4H7Q A;  1JM6 A;  4J1V A;  4W9U A;  4E02 A;  1XFW A;  2YYJ A;  1Y8O A;  1RJ1 A;  3MMO A;  2R0N A;  1IVH A;  2EC5 A;  3FO3 A;  3CE2 A;  3KML A;  4P13 A;  3X0Y A;  2XS8 A;  1SC5 A;  1XFY A;  2ZDY A;  3BNJ A;  3LGQ A;  4V26 A;  4F0X A;  1SIR A;  2LFW A;  5K3J A;  2VF1 A;  4L38 A;  1GJV A;  1FS7 A;  4WJY A;  3RKH A;  3R7K A;  5K3I A;  2Q8F A;  3OIB A;  2CJ7 A;  2R05 A;  2XS1 A;  1JQI A;  4HR3 A;  3D2R A;  2VR0 A;  1XFU A;  1RX0 A;  3HWC A;  3NF4 A;  4AKI A;  3D1I A;  3TZ4 A;  5GJV E;  2EBH X;  2YGW A;  1R3B A;  2YYL A;  4FF2 A;  3LG1 A;  4L1F A;  5K3H A;  2FP2 A;  4DOY A;  4Q5B A;  4FZ4 A;  1K90 A;  4IRN A;  2PNR A;  5M4N A;  1Y8N A;  3PFD A;  1WS9 A;  3AFF A;  3MDE A;  3UBR A;  2E0A A;  2E80 A;  4MP2 A;  1X8Z A;  1XFV A;  4O5M A;  4L3Z A;  3S7W A;  2A1T A;  2CJ5 A;  2R0M A;  2J7A A;  3X29 A;  3SF6 A;  2WBI A;  4DZY A;  3OWM A;  5J71 A;  3D9G A;  3F29 A;  3M9V A;  1FS8 A;  1Y8P A;  4X28 A;  2R02 A;  3VKH A;  1GKX A;  2Z1Q A;  3Q24 A;  3GQT A;  4N5F A;  5M4M A;  1X91 A;  2F6L A;  1PI1 A;  2OEV A;  2HJN A;  5B5V A;  4AI6 A;  3C3L A;  1K8T A;  4HKR A;  2BU8 A;  1BUC A;  1Y0V A;  2REH A;  3MKH A;  4XVX A;  3TTB A;  1EGE A;  1PK0 A;  2CJ6 A;  5J6A A;  2BU6 A;  4NXL A;  1FS9 A;  1S26 A;  1T9G A;  3BNH A;  4JEK A;  2PO4 A;  2Q8I A;  3II9 A;  1RJ4 A;  1SIQ A;  2IX5 A;  3P4T A;  3D9D A;  1GKZ A;  4JIO A;  4MPN A;  4Q5C A;  2BU7 A;  2JBR A;  2YYK A;  2YYI A;  3TZ5 A;  2OJQ A;  2AO2 A;  2D29 A;  2XQR B;  4RM7 A;  2AZE A;  4FF1 A;  4Q17 A;  4MPC A;  4Q4U A;  5B5W A;  5GJW E;  1UDY A;  2JIF A;  2OR0 A;  4AKG A;  4KSF A;  2QR4 A;  1U8V A;  1K93 A;  2VIG A;  4QIC A;  2CJ4 A; 
#chains in the Genus database with same CATH homology
 3MPJ A;  3EON A;  4OO2 A;  2FON A;  4ZXV A;  4ZYJ A;  3SCE A;  1EGD A;  2RDZ A;  2CX9 A;  2PG0 A;  4KCF A;  1R2J A;  2EBA A;  2YYG A;  2JBT A;  3GNC A;  3MXL A;  2IX6 A;  4M9A A;  2JBS A;  2C0U A;  1QDB A;  3D6B A;  1GU6 A;  4L3Y A;  4U83 A;  4Q0T A;  3L1T A;  5K3G A;  3SWO A;  2ZO5 A;  3BNG A;  3B96 A;  1IS2 A;  2RF7 A;  4KTO A;  4X28 C;  3SXQ A;  1W07 A;  2OT4 A;  4G5E A;  3TOR A;  1OAH A;  3OWA A;  2C12 A;  2DDH A;  2RFQ A;  2E81 A;  3MPI A;  3GM6 A;  3MDD A;  3UU9 A;  3D9F A;  4Q1O A;  2YYM A;  1EGC A;  3BNF A;  3FCJ A;  3EOM A;  1UKW A;  3AFE A;  4L3X A;  2UXW A;  3X0X A;  3D9E A;  2ZAF A;  4IV6 A;  2DVL A;  4W9U A;  2YYJ A;  3MMO A;  2R0N A;  1IVH A;  3FO3 A;  3X0Y A;  4P13 A;  3BNJ A;  3LGQ A;  1SIR A;  5K3J A;  4L38 A;  4WJY A;  1FS7 A;  3RKH A;  3R7K A;  5K3I A;  3OIB A;  4HR3 A;  1JQI A;  2VR0 A;  3HWC A;  1RX0 A;  3NF4 A;  3D1I A;  2YYL A;  3LG1 A;  4L1F A;  5K3H A;  4DOY A;  4Q5B A;  4IRN A;  3PFD A;  1WS9 A;  3AFF A;  3MDE A;  3UBR A;  2E80 A;  4O5M A;  4L3Z A;  3S7W A;  2A1T A;  2R0M A;  2J7A A;  3SF6 A;  2WBI A;  3OWM A;  3D9G A;  3F29 A;  3M9V A;  1FS8 A;  4X28 A;  2Z1Q A;  3GQT A;  4N5F A;  3TTB A;  1BUC A;  2REH A;  3MKH A;  4XVX A;  1EGE A;  4NXL A;  1FS9 A;  1T9G A;  3BNH A;  4JEK A;  3II9 A;  1SIQ A;  2IX5 A;  3P4T A;  3D9D A;  4Q5C A;  2YYK A;  2JBR A;  2YYI A;  2D29 A;  4RM7 A;  4Q17 A;  4Q4U A;  1UDY A;  2JIF A;  2OR0 A;  1U8V A;  2VIG A; 
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