5BRKA

Pmob1-lats1 complex
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
203
structure length
192
Chain Sequence
SKFKPKKNIPEELLKHAEALGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
pubmed doi rcsb
molecule tags Transferase/signaling protein
source organism Homo sapiens
molecule keywords MOB kinase activator 1A
total genus 53
structure length 192
sequence length 203
ec nomenclature
pdb deposition date 2015-05-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03637 Mob1_phocein Mob1/phocein family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.30 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 MOB kinase activator 5brkA00
4J1VA 4LQQB 1PI1A 4JIZA 5B6BA 2HJNA 4LQSB 5B5VA 5BRMA 1R3BA 5B5WA 5BRKA
chains in the Genus database with same CATH superfamily
2C0UA 4Q17A 3RKHA 3D9GA 1EGCA 2XS8A 3CRLA 4JIZA 2Q8FA 3Q23A 2GBBA 3S7WA 2E81A 2DVLA 1T9GA 3P4TA 2IX6A 2OJQA 4FZ4A 3D9EA 4XVXA 2CJ4A 1IS2A 2Q8GA 4F0XA 2PNRA 5K3HA 1S26A 1XG2B 2YGWA 3MKHA 2C12A 1JM6A 2BU8A 5GJWE 3TZ2A 1Y8OA 4JIOA 2JIFA 2QR4A 1EGDA 4KCFA 5M4PA 2FP2A 1SIQA 2CX9A 4FF2A 1GKXA 2DDHA 2JBTA 3HWCA 3OWMA 3TZ4A 3VKHA 2YYIA 1FS8A 3MPJA 2VIGA 1WS9A 1Y8NA 1OAHA 1K93A 1QDBA 4E01A 1GKZA 2Z1QA 4OO2A 2PG0A 1W07A 4MP7A 4WJYA 3UU9A 4HKSA 3X29A 2UXWA 1Y8PA 3PFDA 4L3XA 4Q5CA 2Q8IA 2RF7A 4O5MA 2YYGA 2WBIA 3II9A 5K3IA 3VKGA 4W9UA 3X0XA 4V25A 2R03A 1R3BA 3BNGA 4Q0TA 1R2JA 4ZYJA 3Q22A 4KS9A 3Q24A 2EBFX 2JBRA 3B96A 1PK0A 4LQQB 2BU6A 2Q8HA 4X28C 3SWOA 3C3LA 4FF3A 2EC5A 1XFVA 3SCEA 3Q0AA 2YYLA 2JBSA 1XFUA 3CE2A 2LFWA 3D9DA 1FS7A 1GJVA 3L1TA 4HKRA 4ZXVA 4P79A 4MP2A 1RP3A 1LVCA 1RJ4A 2CJ8A 2F6LA 2FONA 2RFQA 2ZAFA 4E02A 5BRMA 1XFYA 3BNHA 5BRKA 1FS9A 5M4KA 2IX5A 1X90A 1XFWA 1UDYA 1XFZA 5J6AA 2A1TA 2CJ5A 3LGQA 4RM7A 2YYKA 3GQTA 2R05A 4AKIA 3TTBA 2OEXA 2CJ7A 3MDEA 3BNJA 2J7AA 3MDDA 4G5EA 3N0RA 4IV6A 4MPNA 3VADA 2OR0A 4KTOA 4MPEA 3C46A 1Y0VA 1JQIA 4MPCA 2XS1A 3F29A 5K3JA 3AFEA 2RDZA 2VF1A 2E80A 4G97A 4M9AA 3X0YA 3KMLA 2ZDXA 2R02A 3MMOA 2D29A 2EBHX 1SIRA 5GJVE 5J71A 5B6BA 2HJNA 2BU7A 4AKHA 3OWAA 4KSAA 4Q4UA 1UKWA 1XFXA 2ZKJA 3D2RA 3OIBA 2YYJA 2EBAA 4H7QA 3R7KA 2BU5A 5M4MA 3NF4A 1IVHA 2R0MA 3M9VA 4H81A 4IRNA 4N5FA 4JEKA 3EOMA 2OEVA 4KSFA 3GM6A 3FCJA 4J1VA 4V26A 1PI1A 2R0NA 3GNCA 3EONA 4L3YA 3AFFA 4LQSB 5B5VA 1EGEA 2BTZA 3D6BA 4Q5BA 2ZO5A 2AZEA 4X28A 3MPIA 4L1FA 5M4NA 3TZ5A 2FP1A 2OT4A 3FO3A 1X91A 2REHA 3LG1A 5K3GA 3SF6A 4FF4A 1SK6A 3D1IA 1U8VA 2YYMA 3BNFA 2CJ6A 2AO2A 2ZDYA 3D9FA 4E00A 3TORA 3TZ0A 4FF1A 4AKGA 1K8TA 3MXLA 2PO4A 4L38A 2BU2A 2XQRB 3CRKA 3UBRA 4DOYA 2VR0A 3SXQA 1RX0A 2E0AA 4NXLA 1X8ZA 1GU6A 1K90A 4L3ZA 4AI6A 4DZYA 1RJ1A 4H85A 4U83A 1BUCA 4P13A 4Q1OA 4QICA 1SC5A 5B5WA 3C2PA 4HR3A
chains in the Genus database with same CATH topology
4J1VA 4LQQB 1PI1A 4JIZA 5B6BA 2HJNA 4LQSB 5B5VA 5BRMA 1R3BA 5B5WA 5BRKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J1V A;  4LQQ B;  1PI1 A;  4JIZ A;  5B6B A;  2HJN A;  4LQS B;  5B5V A;  5BRM A;  1R3B A;  5B5W A;  5BRK A; 
#chains in the Genus database with same CATH topology
 2C0U A;  4Q17 A;  3RKH A;  3D9G A;  1EGC A;  2XS8 A;  3CRL A;  4JIZ A;  2Q8F A;  3Q23 A;  2GBB A;  3S7W A;  2E81 A;  2DVL A;  1T9G A;  3P4T A;  2IX6 A;  2OJQ A;  4FZ4 A;  3D9E A;  4XVX A;  2CJ4 A;  1IS2 A;  2Q8G A;  4F0X A;  2PNR A;  5K3H A;  1S26 A;  1XG2 B;  2YGW A;  3MKH A;  2C12 A;  1JM6 A;  2BU8 A;  5GJW E;  3TZ2 A;  1Y8O A;  4JIO A;  2JIF A;  2QR4 A;  1EGD A;  4KCF A;  5M4P A;  2FP2 A;  1SIQ A;  2CX9 A;  4FF2 A;  1GKX A;  2DDH A;  2JBT A;  3HWC A;  3OWM A;  3TZ4 A;  3VKH A;  2YYI A;  1FS8 A;  3MPJ A;  2VIG A;  1WS9 A;  1Y8N A;  1OAH A;  1K93 A;  1QDB A;  4E01 A;  1GKZ A;  2Z1Q A;  4OO2 A;  2PG0 A;  1W07 A;  4MP7 A;  4WJY A;  3UU9 A;  4HKS A;  3X29 A;  2UXW A;  1Y8P A;  3PFD A;  4L3X A;  4Q5C A;  2Q8I A;  2RF7 A;  4O5M A;  2YYG A;  2WBI A;  3II9 A;  5K3I A;  3VKG A;  4W9U A;  3X0X A;  4V25 A;  2R03 A;  1R3B A;  3BNG A;  4Q0T A;  1R2J A;  4ZYJ A;  3Q22 A;  4KS9 A;  3Q24 A;  2EBF X;  2JBR A;  3B96 A;  1PK0 A;  4LQQ B;  2BU6 A;  2Q8H A;  4X28 C;  3SWO A;  3C3L A;  4FF3 A;  2EC5 A;  1XFV A;  3SCE A;  3Q0A A;  2YYL A;  2JBS A;  1XFU A;  3CE2 A;  2LFW A;  3D9D A;  1FS7 A;  1GJV A;  3L1T A;  4HKR A;  4ZXV A;  4P79 A;  4MP2 A;  1RP3 A;  1LVC A;  1RJ4 A;  2CJ8 A;  2F6L A;  2FON A;  2RFQ A;  2ZAF A;  4E02 A;  5BRM A;  1XFY A;  3BNH A;  5BRK A;  1FS9 A;  5M4K A;  2IX5 A;  1X90 A;  1XFW A;  1UDY A;  1XFZ A;  5J6A A;  2A1T A;  2CJ5 A;  3LGQ A;  4RM7 A;  2YYK A;  3GQT A;  2R05 A;  4AKI A;  3TTB A;  2OEX A;  2CJ7 A;  3MDE A;  3BNJ A;  2J7A A;  3MDD A;  4G5E A;  3N0R A;  4IV6 A;  4MPN A;  3VAD A;  2OR0 A;  4KTO A;  4MPE A;  3C46 A;  1Y0V A;  1JQI A;  4MPC A;  2XS1 A;  3F29 A;  5K3J A;  3AFE A;  2RDZ A;  2VF1 A;  2E80 A;  4G97 A;  4M9A A;  3X0Y A;  3KML A;  2ZDX A;  2R02 A;  3MMO A;  2D29 A;  2EBH X;  1SIR A;  5GJV E;  5J71 A;  5B6B A;  2HJN A;  2BU7 A;  4AKH A;  3OWA A;  4KSA A;  4Q4U A;  1UKW A;  1XFX A;  2ZKJ A;  3D2R A;  3OIB A;  2YYJ A;  2EBA A;  4H7Q A;  3R7K A;  2BU5 A;  5M4M A;  3NF4 A;  1IVH A;  2R0M A;  3M9V A;  4H81 A;  4IRN A;  4N5F A;  4JEK A;  3EOM A;  2OEV A;  4KSF A;  3GM6 A;  3FCJ A;  4J1V A;  4V26 A;  1PI1 A;  2R0N A;  3GNC A;  3EON A;  4L3Y A;  3AFF A;  4LQS B;  5B5V A;  1EGE A;  2BTZ A;  3D6B A;  4Q5B A;  2ZO5 A;  2AZE A;  4X28 A;  3MPI A;  4L1F A;  5M4N A;  3TZ5 A;  2FP1 A;  2OT4 A;  3FO3 A;  1X91 A;  2REH A;  3LG1 A;  5K3G A;  3SF6 A;  4FF4 A;  1SK6 A;  3D1I A;  1U8V A;  2YYM A;  3BNF A;  2CJ6 A;  2AO2 A;  2ZDY A;  3D9F A;  4E00 A;  3TOR A;  3TZ0 A;  4FF1 A;  4AKG A;  1K8T A;  3MXL A;  2PO4 A;  4L38 A;  2BU2 A;  2XQR B;  3CRK A;  3UBR A;  4DOY A;  2VR0 A;  3SXQ A;  1RX0 A;  2E0A A;  4NXL A;  1X8Z A;  1GU6 A;  1K90 A;  4L3Z A;  4AI6 A;  4DZY A;  1RJ1 A;  4H85 A;  4U83 A;  1BUC A;  4P13 A;  4Q1O A;  4QIC A;  1SC5 A;  5B5W A;  3C2P A;  4HR3 A; 
#chains in the Genus database with same CATH homology
 4J1V A;  4LQQ B;  1PI1 A;  4JIZ A;  5B6B A;  2HJN A;  4LQS B;  5B5V A;  5BRM A;  1R3B A;  5B5W A;  5BRK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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