5BRM | Genus

Total Genus 52

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	52
sequence length	160
structure length	154
Chain Sequence	DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 154 atoms

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154 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Transferase/signaling protein
source organism	Homo sapiens
publication title	Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling. pubmed doi rcsb
molecule keywords	MOB kinase activator 1A
total genus	52
structure length	154
sequence length	160
chains with identical sequence	B, C, D, E, F
ec nomenclature
pdb deposition date	2015-05-31

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.20.140.30	Mainly Alpha	Up-down Bundle	Butyryl-CoA Dehydrogenase, subunit A; domain 3	MOB kinase activator	5brmA00

5B5VA 4LQSB 5B5WA 5BRKA 5BRMA 4LQQB 1R3BA 5B6BA 2HJNA 1PI1A 4JIZA 4J1VA
chains in the Genus database with same CATH superfamily

4L3YA 3BNHA 2WBIA 4MPEA 4NXLA 1GKZA 4AKHA 3EOMA 2BU8A 2E0AA 2ZDYA 4IRNA 4ZXVA 3OWAA 3RKHA 3UBRA 2EBFX 4FF4A 2YYGA 2A1TA 4DOYA 3L1TA 4KCFA 3UU9A 2XQRB 1EGDA 1QDBA 2R0NA 3X0YA 5M4KA 1GJVA 1GKXA 2DDHA 4M9AA 2XS1A 4OO2A 3B96A 2Q8IA 3D9GA 3FCJA 2EC5A 3C2PA 1IVHA 3MPIA 1K93A 1XFVA 1IS2A 4XVXA 5J71A 3Q23A 1Y8PA 2AO2A 3BNGA 4KSFA 2D29A 2YYKA 2OT4A 4N5FA 4E01A 4AKGA 3MDEA 2YYIA 1XG2B 3D6BA 4ZYJA 4FF2A 2C0UA 4MPCA 2VR0A 4HKRA 5K3JA 3TZ2A 1R2JA 2JIFA 5M4MA 1X91A 3X0XA 2GBBA 3CRKA 2CJ6A 4J1VA 3PFDA 2R05A 1SC5A 4P79A 3SWOA 2CX9A 2BU2A 1FS8A 2R0MA 2YYJA 4LQQB 1Y0VA 4JIOA 1XFWA 1UKWA 4H81A 4LQSB 2PNRA 2CJ5A 2XS8A 1SIRA 1BUCA 2ZO5A 3D2RA 1WS9A 4Q5BA 2RF7A 5GJVE 4E02A 4U83A 5M4NA 1EGCA 3D9FA 2Z1QA 2CJ4A 3GNCA 4O5MA 5J6AA 2RFQA 4JEKA 4HKSA 3S7WA 2YGWA 3SXQA 2F6LA 3TTBA 2C12A 2CJ7A 3VKHA 1RX0A 4X28A 1X8ZA 4L1FA 3D9EA 2IX6A 1FS9A 4H85A 3LG1A 3GM6A 4F0XA 1RJ4A 3D1IA 3M9VA 3MPJA 2EBHX 2E80A 3X29A 1RJ1A 2PO4A 4G5EA 3CE2A 2BU7A 2PG0A 3EONA 2E81A 2YYLA 2RDZA 2YYMA 5B5VA 1K90A 1UDYA 2VIGA 5BRMA 3II9A 4X28C 4MPNA 4KTOA 3MDDA 4L3ZA 2Q8FA 2FP2A 1EGEA 2OEXA 1JM6A 4MP2A 3NF4A 2EBAA 4V25A 2Q8GA 1XFUA 3TZ0A 3C3LA 4G97A 4RM7A 3R7KA 5B6BA 2FP1A 3HWCA 4FF3A 1XFYA 4V26A 1JQIA 1T9GA 4L38A 2Q8HA 1S26A 3TORA 1U8VA 3SCEA 2J7AA 4HR3A 3D9DA 4L3XA 2JBSA 4JIZA 4FZ4A 1PK0A 3F29A 3N0RA 4AKIA 2CJ8A 1R3BA 4Q17A 4WJYA 3VADA 3MXLA 4MP7A 3TZ4A 5K3HA 1GU6A 1SK6A 2LFWA 3FO3A 2VF1A 2JBTA 5K3IA 2OEVA 2R02A 3Q24A 2OR0A 5K3GA 2ZDXA 3CRLA 2OJQA 4IV6A 1W07A 3TZ5A 4FF1A 1K8TA 2BU5A 2QR4A 3MMOA 4P13A 5GJWE 5BRKA 5M4PA 3C46A 4AI6A 3GQTA 2UXWA 3OIBA 2BTZA 2JBRA 4H7QA 2HJNA 2DVLA 2FONA 2IX5A 2R03A 4Q4UA 4KS9A 1LVCA 3SF6A 3Q22A 5B5WA 3LGQA 1OAHA 4E00A 3P4TA 1FS7A 4QICA 1X90A 1SIQA 2AZEA 2ZAFA 3AFEA 4Q1OA 3BNFA 3OWMA 1RP3A 2REHA 4W9UA 1XFXA 3KMLA 4KSAA 3VKGA 1XFZA 3BNJA 4DZYA 2BU6A 2ZKJA 3MKHA 1Y8OA 4Q0TA 3Q0AA 1PI1A 4Q5CA 3AFFA 1Y8NA
chains in the Genus database with same CATH topology

5B5VA 4LQSB 5B5WA 5BRKA 5BRMA 4LQQB 1R3BA 5B6BA 2HJNA 1PI1A 4JIZA 4J1VA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 5B5V A;  4LQS B;  5B5W A;  5BRK A;  5BRM A;  4LQQ B;  1R3B A;  5B6B A;  2HJN A;  1PI1 A;  4JIZ A;  4J1V A; 
#chains in the Genus database with same CATH topology
 4L3Y A;  3BNH A;  2WBI A;  4MPE A;  4NXL A;  1GKZ A;  4AKH A;  3EOM A;  2BU8 A;  2E0A A;  2ZDY A;  4IRN A;  4ZXV A;  3OWA A;  3RKH A;  3UBR A;  2EBF X;  4FF4 A;  2YYG A;  2A1T A;  4DOY A;  3L1T A;  4KCF A;  3UU9 A;  2XQR B;  1EGD A;  1QDB A;  2R0N A;  3X0Y A;  5M4K A;  1GJV A;  1GKX A;  2DDH A;  4M9A A;  2XS1 A;  4OO2 A;  3B96 A;  2Q8I A;  3D9G A;  3FCJ A;  2EC5 A;  3C2P A;  1IVH A;  3MPI A;  1K93 A;  1XFV A;  1IS2 A;  4XVX A;  5J71 A;  3Q23 A;  1Y8P A;  2AO2 A;  3BNG A;  4KSF A;  2D29 A;  2YYK A;  2OT4 A;  4N5F A;  4E01 A;  4AKG A;  3MDE A;  2YYI A;  1XG2 B;  3D6B A;  4ZYJ A;  4FF2 A;  2C0U A;  4MPC A;  2VR0 A;  4HKR A;  5K3J A;  3TZ2 A;  1R2J A;  2JIF A;  5M4M A;  1X91 A;  3X0X A;  2GBB A;  3CRK A;  2CJ6 A;  4J1V A;  3PFD A;  2R05 A;  1SC5 A;  4P79 A;  3SWO A;  2CX9 A;  2BU2 A;  1FS8 A;  2R0M A;  2YYJ A;  4LQQ B;  1Y0V A;  4JIO A;  1XFW A;  1UKW A;  4H81 A;  4LQS B;  2PNR A;  2CJ5 A;  2XS8 A;  1SIR A;  1BUC A;  2ZO5 A;  3D2R A;  1WS9 A;  4Q5B A;  2RF7 A;  5GJV E;  4E02 A;  4U83 A;  5M4N A;  1EGC A;  3D9F A;  2Z1Q A;  2CJ4 A;  3GNC A;  4O5M A;  5J6A A;  2RFQ A;  4JEK A;  4HKS A;  3S7W A;  2YGW A;  3SXQ A;  2F6L A;  3TTB A;  2C12 A;  2CJ7 A;  3VKH A;  1RX0 A;  4X28 A;  1X8Z A;  4L1F A;  3D9E A;  2IX6 A;  1FS9 A;  4H85 A;  3LG1 A;  3GM6 A;  4F0X A;  1RJ4 A;  3D1I A;  3M9V A;  3MPJ A;  2EBH X;  2E80 A;  3X29 A;  1RJ1 A;  2PO4 A;  4G5E A;  3CE2 A;  2BU7 A;  2PG0 A;  3EON A;  2E81 A;  2YYL A;  2RDZ A;  2YYM A;  5B5V A;  1K90 A;  1UDY A;  2VIG A;  5BRM A;  3II9 A;  4X28 C;  4MPN A;  4KTO A;  3MDD A;  4L3Z A;  2Q8F A;  2FP2 A;  1EGE A;  2OEX A;  1JM6 A;  4MP2 A;  3NF4 A;  2EBA A;  4V25 A;  2Q8G A;  1XFU A;  3TZ0 A;  3C3L A;  4G97 A;  4RM7 A;  3R7K A;  5B6B A;  2FP1 A;  3HWC A;  4FF3 A;  1XFY A;  4V26 A;  1JQI A;  1T9G A;  4L38 A;  2Q8H A;  1S26 A;  3TOR A;  1U8V A;  3SCE A;  2J7A A;  4HR3 A;  3D9D A;  4L3X A;  2JBS A;  4JIZ A;  4FZ4 A;  1PK0 A;  3F29 A;  3N0R A;  4AKI A;  2CJ8 A;  1R3B A;  4Q17 A;  4WJY A;  3VAD A;  3MXL A;  4MP7 A;  3TZ4 A;  5K3H A;  1GU6 A;  1SK6 A;  2LFW A;  3FO3 A;  2VF1 A;  2JBT A;  5K3I A;  2OEV A;  2R02 A;  3Q24 A;  2OR0 A;  5K3G A;  2ZDX A;  3CRL A;  2OJQ A;  4IV6 A;  1W07 A;  3TZ5 A;  4FF1 A;  1K8T A;  2BU5 A;  2QR4 A;  3MMO A;  4P13 A;  5GJW E;  5BRK A;  5M4P A;  3C46 A;  4AI6 A;  3GQT A;  2UXW A;  3OIB A;  2BTZ A;  2JBR A;  4H7Q A;  2HJN A;  2DVL A;  2FON A;  2IX5 A;  2R03 A;  4Q4U A;  4KS9 A;  1LVC A;  3SF6 A;  3Q22 A;  5B5W A;  3LGQ A;  1OAH A;  4E00 A;  3P4T A;  1FS7 A;  4QIC A;  1X90 A;  1SIQ A;  2AZE A;  2ZAF A;  3AFE A;  4Q1O A;  3BNF A;  3OWM A;  1RP3 A;  2REH A;  4W9U A;  1XFX A;  3KML A;  4KSA A;  3VKG A;  1XFZ A;  3BNJ A;  4DZY A;  2BU6 A;  2ZKJ A;  3MKH A;  1Y8O A;  4Q0T A;  3Q0A A;  1PI1 A;  4Q5C A;  3AFF A;  1Y8N A; 
#chains in the Genus database with same CATH homology
 5B5V A;  4LQS B;  5B5W A;  5BRK A;  5BRM A;  4LQQ B;  1R3B A;  5B6B A;  2HJN A;  1PI1 A;  4JIZ A;  4J1V A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5BRMA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN