5BRKA

Pmob1-lats1 complex
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
203
structure length
192
Chain Sequence
SKFKPKKNIPEELLKHAEALGSGNLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
pubmed doi rcsb
molecule tags Transferase/signaling protein
source organism Homo sapiens
molecule keywords MOB kinase activator 1A
total genus 53
structure length 192
sequence length 203
ec nomenclature
pdb deposition date 2015-05-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03637 Mob1_phocein Mob1/phocein family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.140.30 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 MOB kinase activator 5brkA00
5B5VA 5BRMA 1PI1A 5BRKA 5B5WA 1R3BA 4JIZA 5B6BA 4LQQB 4LQSB 2HJNA 4J1VA
chains in the Genus database with same CATH superfamily
4IRNA 5B5VA 3MPJA 2EC5A 3D9DA 4FF2A 2OR0A 3HWCA 3C2PA 3L1TA 2CJ8A 2CX9A 1R2JA 2R02A 2HJNA 2VIGA 2ZO5A 1EGCA 1IVHA 3MDDA 1Y8NA 2IX5A 4KSFA 4L38A 4Q1OA 3RKHA 1PK0A 1U8VA 2BU8A 2C0UA 3VADA 5M4PA 1JM6A 1XFXA 4V26A 3SWOA 3SF6A 5B6BA 4KS9A 5K3HA 2FONA 2Q8IA 4P13A 2ZAFA 4L3XA 4X28C 3B96A 4Q17A 4X28A 1UKWA 3EOMA 4AKIA 1XFYA 4DZYA 4L3YA 5M4KA 2DVLA 2J7AA 3Q22A 1RP3A 2OEVA 5J6AA 4JIOA 3VKHA 3D9EA 5M4MA 1EGEA 2F6LA 4ZXVA 4G97A 2YYIA 1FS9A 4L1FA 2YYLA 4H7QA 3MPIA 3MXLA 3MDEA 1SC5A 2PG0A 2OT4A 4N5FA 4MP2A 3TZ0A 2ZDYA 3MKHA 4RM7A 2E81A 4XVXA 3CE2A 4V25A 3OWMA 4W9UA 3C46A 2IX6A 4ZYJA 5K3JA 3F29A 1PI1A 3TZ2A 5J71A 4F0XA 3C3LA 1SIRA 1RJ1A 4KCFA 4HKRA 3OWAA 3TTBA 3SCEA 4P79A 4Q5BA 4J1VA 2YGWA 3BNGA 2A1TA 2D29A 1EGDA 3EONA 3KMLA 5GJWE 3UU9A 4E02A 3BNFA 4HKSA 2AO2A 2E0AA 2QR4A 2R0NA 2BU7A 3UBRA 5M4NA 2EBHX 1X91A 1FS8A 4G5EA 4M9AA 4MPCA 3TZ4A 1S26A 4Q5CA 3P4TA 2BU5A 5B5WA 4JEKA 2RF7A 3CRKA 3D1IA 1K90A 3D9GA 2Q8FA 3S7WA 2OJQA 4E01A 3Q0AA 2JBTA 3M9VA 2BU2A 2WBIA 2CJ7A 2DDHA 4LQQB 4LQSB 4FF4A 2ZDXA 3CRLA 1SK6A 3OIBA 1W07A 5BRMA 1GJVA 1XFVA 2E80A 1Y8PA 3AFFA 3MMOA 4O5MA 4QICA 2BTZA 3LG1A 4KSAA 3Q23A 1GKZA 1T9GA 2Q8GA 1K8TA 3LGQA 3BNHA 1XFZA 3NF4A 4FZ4A 1RJ4A 1UDYA 2JBRA 1QDBA 3D2RA 3D6BA 3FO3A 4U83A 4FF3A 3SXQA 4OO2A 2YYJA 1GKXA 2LFWA 4Q0TA 2CJ5A 1K93A 1XFUA 2AZEA 1LVCA 2YYGA 2YYMA 2EBAA 3BNJA 4KTOA 2ZKJA 5K3GA 2XQRB 3AFEA 3PFDA 1Y8OA 1OAHA 2RFQA 2C12A 4MPNA 2OEXA 1X90A 4L3ZA 2GBBA 3TORA 3R7KA 3FCJA 1SIQA 2YYKA 3X29A 4DOYA 1X8ZA 4Q4UA 4H81A 1Y0VA 3VKGA 1XFWA 2Q8HA 1BUCA 2EBFX 2R0MA 3GQTA 3X0YA 2JBSA 4AKHA 4WJYA 1WS9A 2FP1A 4FF1A 2FP2A 4JIZA 3GM6A 3II9A 4E00A 1FS7A 5BRKA 1GU6A 2R05A 2BU6A 4HR3A 3Q24A 1JQIA 5GJVE 1XG2B 3D9FA 3N0RA 2VR0A 2CJ4A 2JIFA 2PO4A 3TZ5A 4IV6A 4MPEA 4NXLA 4H85A 2Z1QA 4MP7A 5K3IA 4AI6A 1IS2A 2UXWA 2REHA 4AKGA 2CJ6A 3X0XA 1R3BA 2VF1A 2PNRA 2XS8A 3GNCA 2RDZA 2R03A 2XS1A 1RX0A
chains in the Genus database with same CATH topology
5B5VA 5BRMA 1PI1A 5BRKA 5B5WA 1R3BA 4JIZA 5B6BA 4LQQB 4LQSB 2HJNA 4J1VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5B5V A;  5BRM A;  1PI1 A;  5BRK A;  5B5W A;  1R3B A;  4JIZ A;  5B6B A;  4LQQ B;  4LQS B;  2HJN A;  4J1V A; 
#chains in the Genus database with same CATH topology
 4IRN A;  5B5V A;  3MPJ A;  2EC5 A;  3D9D A;  4FF2 A;  2OR0 A;  3HWC A;  3C2P A;  3L1T A;  2CJ8 A;  2CX9 A;  1R2J A;  2R02 A;  2HJN A;  2VIG A;  2ZO5 A;  1EGC A;  1IVH A;  3MDD A;  1Y8N A;  2IX5 A;  4KSF A;  4L38 A;  4Q1O A;  3RKH A;  1PK0 A;  1U8V A;  2BU8 A;  2C0U A;  3VAD A;  5M4P A;  1JM6 A;  1XFX A;  4V26 A;  3SWO A;  3SF6 A;  5B6B A;  4KS9 A;  5K3H A;  2FON A;  2Q8I A;  4P13 A;  2ZAF A;  4L3X A;  4X28 C;  3B96 A;  4Q17 A;  4X28 A;  1UKW A;  3EOM A;  4AKI A;  1XFY A;  4DZY A;  4L3Y A;  5M4K A;  2DVL A;  2J7A A;  3Q22 A;  1RP3 A;  2OEV A;  5J6A A;  4JIO A;  3VKH A;  3D9E A;  5M4M A;  1EGE A;  2F6L A;  4ZXV A;  4G97 A;  2YYI A;  1FS9 A;  4L1F A;  2YYL A;  4H7Q A;  3MPI A;  3MXL A;  3MDE A;  1SC5 A;  2PG0 A;  2OT4 A;  4N5F A;  4MP2 A;  3TZ0 A;  2ZDY A;  3MKH A;  4RM7 A;  2E81 A;  4XVX A;  3CE2 A;  4V25 A;  3OWM A;  4W9U A;  3C46 A;  2IX6 A;  4ZYJ A;  5K3J A;  3F29 A;  1PI1 A;  3TZ2 A;  5J71 A;  4F0X A;  3C3L A;  1SIR A;  1RJ1 A;  4KCF A;  4HKR A;  3OWA A;  3TTB A;  3SCE A;  4P79 A;  4Q5B A;  4J1V A;  2YGW A;  3BNG A;  2A1T A;  2D29 A;  1EGD A;  3EON A;  3KML A;  5GJW E;  3UU9 A;  4E02 A;  3BNF A;  4HKS A;  2AO2 A;  2E0A A;  2QR4 A;  2R0N A;  2BU7 A;  3UBR A;  5M4N A;  2EBH X;  1X91 A;  1FS8 A;  4G5E A;  4M9A A;  4MPC A;  3TZ4 A;  1S26 A;  4Q5C A;  3P4T A;  2BU5 A;  5B5W A;  4JEK A;  2RF7 A;  3CRK A;  3D1I A;  1K90 A;  3D9G A;  2Q8F A;  3S7W A;  2OJQ A;  4E01 A;  3Q0A A;  2JBT A;  3M9V A;  2BU2 A;  2WBI A;  2CJ7 A;  2DDH A;  4LQQ B;  4LQS B;  4FF4 A;  2ZDX A;  3CRL A;  1SK6 A;  3OIB A;  1W07 A;  5BRM A;  1GJV A;  1XFV A;  2E80 A;  1Y8P A;  3AFF A;  3MMO A;  4O5M A;  4QIC A;  2BTZ A;  3LG1 A;  4KSA A;  3Q23 A;  1GKZ A;  1T9G A;  2Q8G A;  1K8T A;  3LGQ A;  3BNH A;  1XFZ A;  3NF4 A;  4FZ4 A;  1RJ4 A;  1UDY A;  2JBR A;  1QDB A;  3D2R A;  3D6B A;  3FO3 A;  4U83 A;  4FF3 A;  3SXQ A;  4OO2 A;  2YYJ A;  1GKX A;  2LFW A;  4Q0T A;  2CJ5 A;  1K93 A;  1XFU A;  2AZE A;  1LVC A;  2YYG A;  2YYM A;  2EBA A;  3BNJ A;  4KTO A;  2ZKJ A;  5K3G A;  2XQR B;  3AFE A;  3PFD A;  1Y8O A;  1OAH A;  2RFQ A;  2C12 A;  4MPN A;  2OEX A;  1X90 A;  4L3Z A;  2GBB A;  3TOR A;  3R7K A;  3FCJ A;  1SIQ A;  2YYK A;  3X29 A;  4DOY A;  1X8Z A;  4Q4U A;  4H81 A;  1Y0V A;  3VKG A;  1XFW A;  2Q8H A;  1BUC A;  2EBF X;  2R0M A;  3GQT A;  3X0Y A;  2JBS A;  4AKH A;  4WJY A;  1WS9 A;  2FP1 A;  4FF1 A;  2FP2 A;  4JIZ A;  3GM6 A;  3II9 A;  4E00 A;  1FS7 A;  5BRK A;  1GU6 A;  2R05 A;  2BU6 A;  4HR3 A;  3Q24 A;  1JQI A;  5GJV E;  1XG2 B;  3D9F A;  3N0R A;  2VR0 A;  2CJ4 A;  2JIF A;  2PO4 A;  3TZ5 A;  4IV6 A;  4MPE A;  4NXL A;  4H85 A;  2Z1Q A;  4MP7 A;  5K3I A;  4AI6 A;  1IS2 A;  2UXW A;  2REH A;  4AKG A;  2CJ6 A;  3X0X A;  1R3B A;  2VF1 A;  2PNR A;  2XS8 A;  3GNC A;  2RDZ A;  2R03 A;  2XS1 A;  1RX0 A; 
#chains in the Genus database with same CATH homology
 5B5V A;  5BRM A;  1PI1 A;  5BRK A;  5B5W A;  1R3B A;  4JIZ A;  5B6B A;  4LQQ B;  4LQS B;  2HJN A;  4J1V A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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