1SNTA

Structure of the human cytosolic sialidase neu2
Total Genus 94
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
375
structure length
352
Chain Sequence
SLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLNDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Sialidase 2
total genus 94
structure length 352
sequence length 375
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2004-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13088 BNR_2 BNR repeat-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 1sntA00
4MWUA 1BJIA 2QWKA 4XJ8A 3D11A 4QNPA 1NMCA 4FVKA 4WEGA 2F26A 2HTYA 4FPGA 1INHA 2A75A 4B7MA 3TI5A 4MC7A 1INYA 1NNCA 4MZEA 2FHRA 2QWHA 2F12A 2F28A 3JU4A 2VW2A 2AGSA 2QWEA 2W38A 1V2IA 1V0FA 1NSCA 1N1YA 1EUTA 1KITA 1IVEA 4KS3A 1V0ZA 1A4QA 4FPFA 4WEFA 2QWBA 4HZXA 4KS5A 4MJVA 2QWJA 4DGRA 3K38A 3TI4A 4CPLA 4XJRA 4M4NA 2C4AA 4XHBA 1NSBA 2F11A 2YA7A 5B2DA 4Q6KA 4XMIA 7NN9A 1W0PA 4MWWA 1USXA 2BF6A 3INBA 2HTUA 4FPEA 3CL2A 4FPLA 1S0IA 4YZ3A 4FOQA 4XJZA 4QN4A 1MS0A 1SNTA 2F10A 4FOYA 4KS1A 3T1EA 5B2CA 4XHXA 1L7FA 4MWVA 2XZIA 3OPZA 5M1ZA 4FPOB 2F0ZA 4K1KA 3TICA 1W1XA 4M4UA 2AEPA 4GJTA 4XJQA 2BERA 1Z4VA 2YA5A 3H72A 1Z4ZA 1NSDA 3BEQA 5HUGA 1Z4YA 4MWXA 5NN9A 4WA4A 4CPNA 4QN5A 3H73A 6NN9A 3SANA 4UF7A 2AH2A 2QWIA 1F8CA 1NCDN 4XMAA 2HTQA 4B7RA 2C4LA 4XJUA 1IVFA 4K3YA 4XOGA 4GZTA 1V0EA 2VW1A 1DILA 4BBWA 2W5OA 4XYXA 1W21A 2F13A 1W0OA 4FOVA 1MS3A 2ZB5A 1XOGA 1MS5A 1SLLA 3PJQA 4MWQA 4I00A 4XILA 2QWCA 5HUMA 4HZWA 1EUUA 1IVGA 1V3CA 3H6JA 5HUNA 4CPOA 1EURA 4MWJA 5F9TA 2BATA 1F8DA 2VSMA 1W20A 3W09A 4MWRA 1W8NA 3K36A 3CYEA 4KS2A 4CPMA 1DIMA 3K39A 1IVBA 1F8BA 4B7NA 4YZ4A 4NCSA 1MR5A 2HT8A 2F27A 3GVLA 4FPJA 2XZKA 1E8TA 4HZVA 3SILA 1E8VA 1NCCN 1V3DA 3TI6A 2SLIA 4MZAA 2W5NA 1WCQA 1V3BA 1INGA 1VCUA 2QWDA 2F25A 1NCBN 1E8UA 1N1TA 2RKCA 2B8HA 4B7QA 3H71A 2QWGA 4YZ2A 1NMAN 2BZDA 4MJUA 4QN6A 4YZ1A 1MS9A 4K1JA 3NN9A 3TIBA 1A4GA 2ZB6A 4FOWA 4GZPA 2QWAA 4XIOA 4GZOA 4X47A 4FPCA 4QN3A 4QN7A 4X49A 2HTRA 1MWEA 1WCSA 4FP2A 1SLIA 1MS4A 1N1VA 4GB1A 3A71A 1INFA 5JYYA 2F29A 4FPHA 2HU4A 1MS8A 4HZZA 1INVA 2VK7A 4GZSA 4D8SA 4GEZA 4X6KA 1F8EA 2HT7A 1NNBA 4M4VA 3CL0A 2W20A 4WA5A 3A72A 3GVJA 2VWDA 4GDIA 4FJ6A 1Z4WA 4H52A 1B9TA 3B69A 2YA4A 3ALWA 4HZYA 3K3AA 4HIZA 4YW1A 1XOEA 3O9KA 4FPYA 2CMLA 1L7HA 4MWLA 4GDJA 3TI3A 3CKZA 1INWA 4SLIA 3GVKA 1Z50A 4WA3A 4NN9A 4GZWA 2VVZA 1N1SA 2AEQA 5HUKA 3ALXA 1EUSA 4NC5A 4GZXA 2YA8A 4YW2A 1IVDA 1INXA 3K37A 1VCJA 1NN2A 2F24A 4FZHA 2X9MA 1SO7A 2QWFA 2YA6A 1B9SA 3TIAA 2SIMA 2SILA 4M3MA 1S0JA 4CPYA 3O9JA 4X4AA 1NMBN 4FP3A 4CPZA 2HU0A 3TI8A 2VW0A 3SLIA 4XJ9A 1B9VA 2XZJA 3NSSA 4YW5A 4XIKA 2HTVA 4B7JA 4FQ4A 1Z4XA 1V3EA 4MWYA 4FPKA 1MZ5A 4XJWA 4JF7A 2HTWA 4KS4A 1MZ6A 5HX0A 3D12A 4J9TA 1W8OA 3B7EA 4YW3A 1A14N 2JKBA 2XCYA 4XE9A 2HT5A 4K1IA 1USRA 3SALA 2YDPA 1NCAN 1L7GA 2YDTA 4XJAA 1IVCA 4H53A 1NNAA 4YW4A 4YZ5A 2VK6A 4GZQA 2VSKA 4K1HA 2VK5A 1MS1A 4MX0A
chains in the Genus database with same CATH superfamily
1OFZA 4MWUA 1BJIA 2QWKA 4XJ8A 3D11A 4QNPA 1NMCA 3O4PA 4CH9A 4FVKA 4WEGA 2F26A 2HTYA 4FPGA 1INHA 2IAWA 3Q6PA 5CGJA 2A75A 4B7MA 3TI5A 4MC7A 1INYA 4G3NA 5GX5A 1NNCA 4MZEA 3II7A 2FHRA 2QWHA 2IAOA 4GN7A 4AGTA 2F12A 4AH4A 2F28A 3JU4A 1CQ1A 5FNQA 2VW2A 2AGSA 3VNGA 2G8SA 5GX1A 2QWEA 1CVMA 2W38A 1V2IA 1V0FA 1NSCA 3HRPA 1S18A 2ZWAA 4DG6A 1EUTA 5FNSA 1KITA 1IVEA 4JMLA 4KS3A 4C1YB 1V0ZA 1A4QA 4FPFA 2Z32A 4WEFA 1N6EA 1SUUA 2QWBA 1E1AA 2DSOA 4HZXA 4KS5A 4MJVA 2QWJA 4DGRA 3K38A 1N6FA 3DASA 3TI4A 4CPLA 4XJRA 4M4NA 2C4AA 4MX0A 4XHBA 1NSBA 2F11A 2YA7A 5B2DA 1CRZA 4Q6KA 4XMIA 7NN9A 1W0PA 4MWWA 1USXA 2BF6A 2VAQA 1RWIA 3INBA 2HTUA 3V65B 4GNBA 4GNCA 4FPEA 3CL2A 4FPLA 1V04A 1S0IA 4YZ3A 4FOQA 4XJZA 4O5SA 2GVVA 4QN4A 1MS0A 1SNTA 2F10A 4FOYA 4KS1A 3T1EA 5B2CA 4XHXA 1L7FA 4MWVA 2XZIA 4D52A 2FP9A 3OPZA 5M1ZA 4FPOB 3V1SA 2F0ZA 4IFNX 4K1KA 3TICA 1W1XA 4M4UA 2POOA 2ZW9A 5D9BA 2AEPA 1H6LA 5FZJA 4GJTA 4XJQA 2BERA 2XN4A 1Z4VA 2YA5A 4XMBA 3VNHA 3H72A 1Z4ZA 1NSDA 3BEQA 5HUGA 1Z4YA 4MWXA 5NN9A 4WA4A 4CPNA 2IAQA 4QN5A 2IVZA 3H73A 6NN9A 3SANA 4UF7A 2AH2A 2IARA 2QWIA 1F8CA 1NCDN 3G4HA 4GN8A 4XMAA 5FZNA 1CRUA 2HTQA 4D52B 4B7RA 1ZI0A 2C4LA 3V64C 5FNRA 4XJUA 1IVFA 4K3YA 4PWZA 4XOGA 4GZTA 2FP8A 1V0EA 2VW1A 1DILA 4BBWA 1PJXA 2W5OA 4HHQA 4XYXA 1W21A 2F13A 3SOQA 4YY8A 2WOZA 1W0OA 4FOVA 1MS3A 2ZB5A 1WP5A 2GVWA 3A9GA 1XOGA 1MS5A 1SLLA 3PJQA 3NO0A 4MWQA 2ISMA 4I00A 4XILA 3SRGA 2DYHA 2QWCA 5HUMA 4HZWA 4Q1UA 1EUUA 3TC9A 1IVGA 1N6DA 1V3CA 3H6JA 5GTQA 5HUNA 4CPOA 1EURA 4IMBA 4MWJA 5F9TA 2BATA 1F8DA 1U6DX 2VSMA 4ZY3A 1W20A 5D9DA 3W09A 4MWRA 3AMRA 1W8NA 2W8BA 2IAPA 3K36A 3CYEA 4KS2A 4CPMA 1DIMA 3S2KA 2IAVA 4A0PA 3K39A 1IVBA 1F8BA 4B7NA 4YZ4A 4D4UA 5GX3A 4NCSA 1MR5A 3SREA 3WDZA 2HT8A 2QE8A 2F27A 2GVXA 3GVLA 2HQSA 4FPJA 2XZKA 1E8TA 3AMSA 4HZVA 3A9HA 3SILA 1E8VA 1NCCN 1V3DA 3TI6A 3WWAA 4O5TA 1ZGKA 2SLIA 4MZAA 5GX4A 2W5NA 1WCQA 1V3BA 3ADEA 4L7BA 1INGA 4L7CA 1VCUA 2QWDA 4ASCA 2F25A 3L6VA 1NCBN 1E8UA 1N1TA 2RKCA 2B8HA 2ZZKA 5EO7A 3Q6TA 3P5BL 4B7QA 3H71A 4GN9A 2W8BB 1K32A 3DR2A 2QWGA 4YZ2A 1NMAN 2BZDA 3HLIA 4IFLX 4CSDA 4ZLRA 4L7DA 4MJUA 5EO8A 3IAXA 4QN6A 4YZ1A 4AGIA 3WN7A 1MS9A 4K1JA 3NN9A 3TIBA 3LI5A 2IATA 3ZGCA 1A4GA 3HLHA 2ZB6A 4FOWA 4GZPA 2QWAA 2DG1A 4XIOA 4GZOA 4X47A 4FPCA 4QN3A 4QN7A 4X49A 2HTRA 1MWEA 4CHBA 1WCSA 3LI4A 4FP2A 1SLIA 1IUBA 1MS4A 1N1VA 3LI3A 3UC1A 4GB1A 3A71A 1INFA 4HHOA 5JYYA 1C9UA 2F29A 3Q6KA 2HU4A 4FPHA 1MS8A 4HZZA 1INVA 1NPEA 2VK7A 4GZSA 4D8SA 4GEZA 4X6KA 1F8EA 2HT7A 1NNBA 4M4VA 3CL0A 3KGGA 2W20A 4WA5A 2IAUA 3A72A 5D9CA 3GVJA 3ZGDA 2VWDA 4GDIA 4FJ6A 1Z4WA 2P4OA 1B9TA 4H52A 3B69A 2YA4A 3ALWA 4HZYA 3K3AA 4IFJA 4IN4A 4HIZA 4YW1A 1XOEA 4ZGCA 3O9KA 4FPYA 2CMLA 2IASA 1L7HA 4GNAA 4MWLA 4GDJA 3TI3A 3CKZA 1INWA 4SLIA 3GVKA 1C5KA 1Z50A 2FPCA 5GX2A 1N7DA 4WA3A 4NN9A 4GZWA 2VVZA 1N1SA 2AEQA 5HUKA 3ALXA 1EUSA 5FWWA 4NC5A 4GZXA 2YA8A 4YW2A 1IVDA 1RWLA 1QLGA 1INXA 3I1CA 3K37A 1VCJA 1NN2A 2DG0A 2F24A 4FZHA 4AHAA 2X9MA 1SO7A 4UOUA 2QWFA 3G4EA 4D52C 2YA6A 1B9SA 3S94A 3TIAA 2SIMA 2SILA 3SOBB 3E5ZA 3S8ZA 2GHSA 4N1BA 4IQKA 4M3MA 1S0JA 4CPYA 2OJHA 3FVZA 5F72C 3O9JA 3SOVA 4X4AA 1NMBN 4FP3A 4CPZA 2HU0A 5H47A 3TI8A 1Q7FA 2VW0A 3SLIA 3KYAA 4XJ9A 1B9VA 2XZJA 2H2UA 3NSSA 4YW5A 4XIKA 2HTVA 2VPJA 4B7JA 4FQ4A 1Z4XA 1V3EA 4MWYA 4FPKA 4HW6A 2H2NA 1MZ5A 1QBIA 3U0SA 4XJWA 1S1DA 2HTWA 4JF7A 4KS4A 1MZ6A 4R40A 5HX0A 3D12A 4J9TA 3FW0A 5FNUA 1W8OA 3B7EA 1X2JA 2FPBA 4YW3A 1A14N 5EX7A 2JKBA 2XCYA 4XE9A 2HT5A 1IJQA 3WW9A 4K1IA 2FLUX 3S8VA 1USRA 3SALA 2YDPA 1IUCA 1NCAN 1L7GA 2YDTA 4XJAA 1IVCA 4IYGA 4H53A 5FNTA 1NNAA 2GVUA 4YW4A 3BYCA 2IAXA 4YZ5A 1X2RA 1POOA 2VK6A 4GZQA 2VSKA 4C1YA 4K1HA 2VK5A 1MS1A 1N1YA 2V91A
chains in the Genus database with same CATH topology
4MWUA 1BJIA 2QWKA 4XJ8A 3D11A 4QNPA 1NMCA 4FVKA 4WEGA 2F26A 2HTYA 4FPGA 1INHA 2A75A 4B7MA 3TI5A 4MC7A 1INYA 1NNCA 4MZEA 2FHRA 2QWHA 2F12A 2F28A 3JU4A 2VW2A 2AGSA 2QWEA 2W38A 1V2IA 1V0FA 1NSCA 1S18A 1N1YA 1EUTA 1KITA 1IVEA 4KS3A 1V0ZA 1A4QA 4FPFA 4WEFA 2QWBA 4HZXA 4KS5A 4MJVA 2QWJA 4DGRA 3K38A 3TI4A 4CPLA 4XJRA 4M4NA 2C4AA 4XHBA 1NSBA 2F11A 2YA7A 5B2DA 4Q6KA 4XMIA 7NN9A 1W0PA 4MWWA 1USXA 2BF6A 3INBA 2HTUA 4FPEA 3CL2A 4FPLA 1S0IA 4YZ3A 4FOQA 4XJZA 4QN4A 1MS0A 1SNTA 2F10A 4FOYA 4KS1A 3T1EA 5B2CA 4XHXA 1L7FA 4MWVA 2XZIA 3OPZA 5M1ZA 4FPOB 2F0ZA 4K1KA 3TICA 1W1XA 4M4UA 2AEPA 4GJTA 4XJQA 2BERA 1Z4VA 2YA5A 3H72A 1Z4ZA 1NSDA 3BEQA 5HUGA 1Z4YA 4MWXA 5NN9A 4WA4A 4CPNA 4QN5A 3H73A 6NN9A 3SANA 4UF7A 2AH2A 2QWIA 1F8CA 1NCDN 4XMAA 2HTQA 4B7RA 2C4LA 4XJUA 1IVFA 4K3YA 4XOGA 4GZTA 1V0EA 2VW1A 1DILA 4BBWA 2W5OA 4XYXA 1W21A 2F13A 1W0OA 4FOVA 1MS3A 2ZB5A 1XOGA 1MS5A 1SLLA 3PJQA 4MWQA 4I00A 4XILA 2QWCA 5HUMA 4HZWA 1EUUA 1IVGA 1V3CA 3H6JA 5HUNA 4CPOA 1EURA 4MWJA 5F9TA 2BATA 1F8DA 2VSMA 1W20A 3W09A 4MWRA 1W8NA 3K36A 3CYEA 4KS2A 4CPMA 1DIMA 3K39A 1IVBA 1F8BA 4B7NA 4YZ4A 4NCSA 1MR5A 2HT8A 2F27A 3GVLA 4FPJA 2XZKA 1E8TA 4HZVA 3SILA 1E8VA 1NCCN 1V3DA 3TI6A 2SLIA 4MZAA 2W5NA 1WCQA 1V3BA 1INGA 1VCUA 2QWDA 2F25A 1NCBN 1E8UA 1N1TA 2RKCA 2B8HA 4B7QA 3H71A 2QWGA 4YZ2A 1NMAN 2BZDA 4MJUA 4QN6A 4YZ1A 1MS9A 4K1JA 3NN9A 3TIBA 1A4GA 2ZB6A 4FOWA 4GZPA 2QWAA 4XIOA 4GZOA 4X47A 4FPCA 4QN3A 4QN7A 4X49A 2HTRA 1MWEA 1WCSA 4FP2A 1SLIA 1MS4A 1N1VA 4GB1A 3A71A 1INFA 5JYYA 2F29A 4FPHA 2HU4A 1MS8A 4HZZA 1INVA 2VK7A 4GZSA 4D8SA 4GEZA 4X6KA 1F8EA 2HT7A 1NNBA 4M4VA 3CL0A 2W20A 4WA5A 3A72A 3GVJA 2VWDA 4GDIA 4FJ6A 1Z4WA 4H52A 1B9TA 3B69A 2YA4A 3ALWA 4HZYA 3K3AA 4HIZA 4YW1A 1XOEA 3O9KA 4FPYA 2CMLA 1L7HA 4MWLA 4GDJA 3TI3A 3CKZA 1INWA 4SLIA 3GVKA 1Z50A 4WA3A 4NN9A 4GZWA 2VVZA 1N1SA 2AEQA 5HUKA 3ALXA 1EUSA 4NC5A 4GZXA 2YA8A 4YW2A 1IVDA 1INXA 3K37A 1VCJA 1NN2A 2F24A 4FZHA 2X9MA 1SO7A 2QWFA 2YA6A 1B9SA 3TIAA 2SIMA 2SILA 4M3MA 1S0JA 4CPYA 3O9JA 4X4AA 1NMBN 4FP3A 4CPZA 2HU0A 3TI8A 2VW0A 3SLIA 4XJ9A 1B9VA 2XZJA 2H2UA 3NSSA 4YW5A 4XIKA 2HTVA 4B7JA 4FQ4A 1Z4XA 1V3EA 4MWYA 4FPKA 2H2NA 1MZ5A 4XJWA 1S1DA 2HTWA 4JF7A 4KS4A 1MZ6A 5HX0A 3D12A 4J9TA 1W8OA 3B7EA 4YW3A 1A14N 2JKBA 2XCYA 4XE9A 2HT5A 4K1IA 1USRA 3SALA 2YDPA 1NCAN 1L7GA 2YDTA 4XJAA 1IVCA 4H53A 1NNAA 4YW4A 4YZ5A 2VK6A 4GZQA 2VSKA 4K1HA 2VK5A 1MS1A 4MX0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MWU A;  1BJI A;  2QWK A;  4XJ8 A;  3D11 A;  4QNP A;  1NMC A;  4FVK A;  4WEG A;  2F26 A;  2HTY A;  4FPG A;  1INH A;  2A75 A;  4B7M A;  3TI5 A;  4MC7 A;  1INY A;  1NNC A;  4MZE A;  2FHR A;  2QWH A;  2F12 A;  2F28 A;  3JU4 A;  2VW2 A;  2AGS A;  2QWE A;  2W38 A;  1V2I A;  1V0F A;  1NSC A;  1N1Y A;  1EUT A;  1KIT A;  1IVE A;  4KS3 A;  1V0Z A;  1A4Q A;  4FPF A;  4WEF A;  2QWB A;  4HZX A;  4KS5 A;  4MJV A;  2QWJ A;  4DGR A;  3K38 A;  3TI4 A;  4CPL A;  4XJR A;  4M4N A;  2C4A A;  4XHB A;  1NSB A;  2F11 A;  2YA7 A;  5B2D A;  4Q6K A;  4XMI A;  7NN9 A;  1W0P A;  4MWW A;  1USX A;  2BF6 A;  3INB A;  2HTU A;  4FPE A;  3CL2 A;  4FPL A;  1S0I A;  4YZ3 A;  4FOQ A;  4XJZ A;  4QN4 A;  1MS0 A;  1SNT A;  2F10 A;  4FOY A;  4KS1 A;  3T1E A;  5B2C A;  4XHX A;  1L7F A;  4MWV A;  2XZI A;  3OPZ A;  5M1Z A;  4FPO B;  2F0Z A;  4K1K A;  3TIC A;  1W1X A;  4M4U A;  2AEP A;  4GJT A;  4XJQ A;  2BER A;  1Z4V A;  2YA5 A;  3H72 A;  1Z4Z A;  1NSD A;  3BEQ A;  5HUG A;  1Z4Y A;  4MWX A;  5NN9 A;  4WA4 A;  4CPN A;  4QN5 A;  3H73 A;  6NN9 A;  3SAN A;  4UF7 A;  2AH2 A;  2QWI A;  1F8C A;  1NCD N;  4XMA A;  2HTQ A;  4B7R A;  2C4L A;  4XJU A;  1IVF A;  4K3Y A;  4XOG A;  4GZT A;  1V0E A;  2VW1 A;  1DIL A;  4BBW A;  2W5O A;  4XYX A;  1W21 A;  2F13 A;  1W0O A;  4FOV A;  1MS3 A;  2ZB5 A;  1XOG A;  1MS5 A;  1SLL A;  3PJQ A;  4MWQ A;  4I00 A;  4XIL A;  2QWC A;  5HUM A;  4HZW A;  1EUU A;  1IVG A;  1V3C A;  3H6J A;  5HUN A;  4CPO A;  1EUR A;  4MWJ A;  5F9T A;  2BAT A;  1F8D A;  2VSM A;  1W20 A;  3W09 A;  4MWR A;  1W8N A;  3K36 A;  3CYE A;  4KS2 A;  4CPM A;  1DIM A;  3K39 A;  1IVB A;  1F8B A;  4B7N A;  4YZ4 A;  4NCS A;  1MR5 A;  2HT8 A;  2F27 A;  3GVL A;  4FPJ A;  2XZK A;  1E8T A;  4HZV A;  3SIL A;  1E8V A;  1NCC N;  1V3D A;  3TI6 A;  2SLI A;  4MZA A;  2W5N A;  1WCQ A;  1V3B A;  1ING A;  1VCU A;  2QWD A;  2F25 A;  1NCB N;  1E8U A;  1N1T A;  2RKC A;  2B8H A;  4B7Q A;  3H71 A;  2QWG A;  4YZ2 A;  1NMA N;  2BZD A;  4MJU A;  4QN6 A;  4YZ1 A;  1MS9 A;  4K1J A;  3NN9 A;  3TIB A;  1A4G A;  2ZB6 A;  4FOW A;  4GZP A;  2QWA A;  4XIO A;  4GZO A;  4X47 A;  4FPC A;  4QN3 A;  4QN7 A;  4X49 A;  2HTR A;  1MWE A;  1WCS A;  4FP2 A;  1SLI A;  1MS4 A;  1N1V A;  4GB1 A;  3A71 A;  1INF A;  5JYY A;  2F29 A;  4FPH A;  2HU4 A;  1MS8 A;  4HZZ A;  1INV A;  2VK7 A;  4GZS A;  4D8S A;  4GEZ A;  4X6K A;  1F8E A;  2HT7 A;  1NNB A;  4M4V A;  3CL0 A;  2W20 A;  4WA5 A;  3A72 A;  3GVJ A;  2VWD A;  4GDI A;  4FJ6 A;  1Z4W A;  4H52 A;  1B9T A;  3B69 A;  2YA4 A;  3ALW A;  4HZY A;  3K3A A;  4HIZ A;  4YW1 A;  1XOE A;  3O9K A;  4FPY A;  2CML A;  1L7H A;  4MWL A;  4GDJ A;  3TI3 A;  3CKZ A;  1INW A;  4SLI A;  3GVK A;  1Z50 A;  4WA3 A;  4NN9 A;  4GZW A;  2VVZ A;  1N1S A;  2AEQ A;  5HUK A;  3ALX A;  1EUS A;  4NC5 A;  4GZX A;  2YA8 A;  4YW2 A;  1IVD A;  1INX A;  3K37 A;  1VCJ A;  1NN2 A;  2F24 A;  4FZH A;  2X9M A;  1SO7 A;  2QWF A;  2YA6 A;  1B9S A;  3TIA A;  2SIM A;  2SIL A;  4M3M A;  1S0J A;  4CPY A;  3O9J A;  4X4A A;  1NMB N;  4FP3 A;  4CPZ A;  2HU0 A;  3TI8 A;  2VW0 A;  3SLI A;  4XJ9 A;  1B9V A;  2XZJ A;  3NSS A;  4YW5 A;  4XIK A;  2HTV A;  4B7J A;  4FQ4 A;  1Z4X A;  1V3E A;  4MWY A;  4FPK A;  1MZ5 A;  4XJW A;  4JF7 A;  2HTW A;  4KS4 A;  1MZ6 A;  5HX0 A;  3D12 A;  4J9T A;  1W8O A;  3B7E A;  4YW3 A;  1A14 N;  2JKB A;  2XCY A;  4XE9 A;  2HT5 A;  4K1I A;  1USR A;  3SAL A;  2YDP A;  1NCA N;  1L7G A;  2YDT A;  4XJA A;  1IVC A;  4H53 A;  1NNA A;  4YW4 A;  4YZ5 A;  2VK6 A;  4GZQ A;  2VSK A;  4K1H A;  2VK5 A;  1MS1 A;  4MX0 A; 
#chains in the Genus database with same CATH topology
 1OFZ A;  4MWU A;  1BJI A;  2QWK A;  4XJ8 A;  3D11 A;  4QNP A;  1NMC A;  3O4P A;  4CH9 A;  4FVK A;  4WEG A;  2F26 A;  2HTY A;  4FPG A;  1INH A;  2IAW A;  3Q6P A;  5CGJ A;  2A75 A;  4B7M A;  3TI5 A;  4MC7 A;  1INY A;  4G3N A;  5GX5 A;  1NNC A;  4MZE A;  3II7 A;  2FHR A;  2QWH A;  2IAO A;  4GN7 A;  4AGT A;  2F12 A;  4AH4 A;  2F28 A;  3JU4 A;  1CQ1 A;  5FNQ A;  2VW2 A;  2AGS A;  3VNG A;  2G8S A;  5GX1 A;  2QWE A;  1CVM A;  2W38 A;  1V2I A;  1V0F A;  1NSC A;  3HRP A;  1S18 A;  2ZWA A;  4DG6 A;  1EUT A;  5FNS A;  1KIT A;  1IVE A;  4JML A;  4KS3 A;  4C1Y B;  1V0Z A;  1A4Q A;  4FPF A;  2Z32 A;  4WEF A;  1N6E A;  1SUU A;  2QWB A;  1E1A A;  2DSO A;  4HZX A;  4KS5 A;  4MJV A;  2QWJ A;  4DGR A;  3K38 A;  1N6F A;  3DAS A;  3TI4 A;  4CPL A;  4XJR A;  4M4N A;  2C4A A;  4MX0 A;  4XHB A;  1NSB A;  2F11 A;  2YA7 A;  5B2D A;  1CRZ A;  4Q6K A;  4XMI A;  7NN9 A;  1W0P A;  4MWW A;  1USX A;  2BF6 A;  2VAQ A;  1RWI A;  3INB A;  2HTU A;  3V65 B;  4GNB A;  4GNC A;  4FPE A;  3CL2 A;  4FPL A;  1V04 A;  1S0I A;  4YZ3 A;  4FOQ A;  4XJZ A;  4O5S A;  2GVV A;  4QN4 A;  1MS0 A;  1SNT A;  2F10 A;  4FOY A;  4KS1 A;  3T1E A;  5B2C A;  4XHX A;  1L7F A;  4MWV A;  2XZI A;  4D52 A;  2FP9 A;  3OPZ A;  5M1Z A;  4FPO B;  3V1S A;  2F0Z A;  4IFN X;  4K1K A;  3TIC A;  1W1X A;  4M4U A;  2POO A;  2ZW9 A;  5D9B A;  2AEP A;  1H6L A;  5FZJ A;  4GJT A;  4XJQ A;  2BER A;  2XN4 A;  1Z4V A;  2YA5 A;  4XMB A;  3VNH A;  3H72 A;  1Z4Z A;  1NSD A;  3BEQ A;  5HUG A;  1Z4Y A;  4MWX A;  5NN9 A;  4WA4 A;  4CPN A;  2IAQ A;  4QN5 A;  2IVZ A;  3H73 A;  6NN9 A;  3SAN A;  4UF7 A;  2AH2 A;  2IAR A;  2QWI A;  1F8C A;  1NCD N;  3G4H A;  4GN8 A;  4XMA A;  5FZN A;  1CRU A;  2HTQ A;  4D52 B;  4B7R A;  1ZI0 A;  2C4L A;  3V64 C;  5FNR A;  4XJU A;  1IVF A;  4K3Y A;  4PWZ A;  4XOG A;  4GZT A;  2FP8 A;  1V0E A;  2VW1 A;  1DIL A;  4BBW A;  1PJX A;  2W5O A;  4HHQ A;  4XYX A;  1W21 A;  2F13 A;  3SOQ A;  4YY8 A;  2WOZ A;  1W0O A;  4FOV A;  1MS3 A;  2ZB5 A;  1WP5 A;  2GVW A;  3A9G A;  1XOG A;  1MS5 A;  1SLL A;  3PJQ A;  3NO0 A;  4MWQ A;  2ISM A;  4I00 A;  4XIL A;  3SRG A;  2DYH A;  2QWC A;  5HUM A;  4HZW A;  4Q1U A;  1EUU A;  3TC9 A;  1IVG A;  1N6D A;  1V3C A;  3H6J A;  5GTQ A;  5HUN A;  4CPO A;  1EUR A;  4IMB A;  4MWJ A;  5F9T A;  2BAT A;  1F8D A;  1U6D X;  2VSM A;  4ZY3 A;  1W20 A;  5D9D A;  3W09 A;  4MWR A;  3AMR A;  1W8N A;  2W8B A;  2IAP A;  3K36 A;  3CYE A;  4KS2 A;  4CPM A;  1DIM A;  3S2K A;  2IAV A;  4A0P A;  3K39 A;  1IVB A;  1F8B A;  4B7N A;  4YZ4 A;  4D4U A;  5GX3 A;  4NCS A;  1MR5 A;  3SRE A;  3WDZ A;  2HT8 A;  2QE8 A;  2F27 A;  2GVX A;  3GVL A;  2HQS A;  4FPJ A;  2XZK A;  1E8T A;  3AMS A;  4HZV A;  3A9H A;  3SIL A;  1E8V A;  1NCC N;  1V3D A;  3TI6 A;  3WWA A;  4O5T A;  1ZGK A;  2SLI A;  4MZA A;  5GX4 A;  2W5N A;  1WCQ A;  1V3B A;  3ADE A;  4L7B A;  1ING A;  4L7C A;  1VCU A;  2QWD A;  4ASC A;  2F25 A;  3L6V A;  1NCB N;  1E8U A;  1N1T A;  2RKC A;  2B8H A;  2ZZK A;  5EO7 A;  3Q6T A;  3P5B L;  4B7Q A;  3H71 A;  4GN9 A;  2W8B B;  1K32 A;  3DR2 A;  2QWG A;  4YZ2 A;  1NMA N;  2BZD A;  3HLI A;  4IFL X;  4CSD A;  4ZLR A;  4L7D A;  4MJU A;  5EO8 A;  3IAX A;  4QN6 A;  4YZ1 A;  4AGI A;  3WN7 A;  1MS9 A;  4K1J A;  3NN9 A;  3TIB A;  3LI5 A;  2IAT A;  3ZGC A;  1A4G A;  3HLH A;  2ZB6 A;  4FOW A;  4GZP A;  2QWA A;  2DG1 A;  4XIO A;  4GZO A;  4X47 A;  4FPC A;  4QN3 A;  4QN7 A;  4X49 A;  2HTR A;  1MWE A;  4CHB A;  1WCS A;  3LI4 A;  4FP2 A;  1SLI A;  1IUB A;  1MS4 A;  1N1V A;  3LI3 A;  3UC1 A;  4GB1 A;  3A71 A;  1INF A;  4HHO A;  5JYY A;  1C9U A;  2F29 A;  3Q6K A;  2HU4 A;  4FPH A;  1MS8 A;  4HZZ A;  1INV A;  1NPE A;  2VK7 A;  4GZS A;  4D8S A;  4GEZ A;  4X6K A;  1F8E A;  2HT7 A;  1NNB A;  4M4V A;  3CL0 A;  3KGG A;  2W20 A;  4WA5 A;  2IAU A;  3A72 A;  5D9C A;  3GVJ A;  3ZGD A;  2VWD A;  4GDI A;  4FJ6 A;  1Z4W A;  2P4O A;  1B9T A;  4H52 A;  3B69 A;  2YA4 A;  3ALW A;  4HZY A;  3K3A A;  4IFJ A;  4IN4 A;  4HIZ A;  4YW1 A;  1XOE A;  4ZGC A;  3O9K A;  4FPY A;  2CML A;  2IAS A;  1L7H A;  4GNA A;  4MWL A;  4GDJ A;  3TI3 A;  3CKZ A;  1INW A;  4SLI A;  3GVK A;  1C5K A;  1Z50 A;  2FPC A;  5GX2 A;  1N7D A;  4WA3 A;  4NN9 A;  4GZW A;  2VVZ A;  1N1S A;  2AEQ A;  5HUK A;  3ALX A;  1EUS A;  5FWW A;  4NC5 A;  4GZX A;  2YA8 A;  4YW2 A;  1IVD A;  1RWL A;  1QLG A;  1INX A;  3I1C A;  3K37 A;  1VCJ A;  1NN2 A;  2DG0 A;  2F24 A;  4FZH A;  4AHA A;  2X9M A;  1SO7 A;  4UOU A;  2QWF A;  3G4E A;  4D52 C;  2YA6 A;  1B9S A;  3S94 A;  3TIA A;  2SIM A;  2SIL A;  3SOB B;  3E5Z A;  3S8Z A;  2GHS A;  4N1B A;  4IQK A;  4M3M A;  1S0J A;  4CPY A;  2OJH A;  3FVZ A;  5F72 C;  3O9J A;  3SOV A;  4X4A A;  1NMB N;  4FP3 A;  4CPZ A;  2HU0 A;  5H47 A;  3TI8 A;  1Q7F A;  2VW0 A;  3SLI A;  3KYA A;  4XJ9 A;  1B9V A;  2XZJ A;  2H2U A;  3NSS A;  4YW5 A;  4XIK A;  2HTV A;  2VPJ A;  4B7J A;  4FQ4 A;  1Z4X A;  1V3E A;  4MWY A;  4FPK A;  4HW6 A;  2H2N A;  1MZ5 A;  1QBI A;  3U0S A;  4XJW A;  1S1D A;  2HTW A;  4JF7 A;  4KS4 A;  1MZ6 A;  4R40 A;  5HX0 A;  3D12 A;  4J9T A;  3FW0 A;  5FNU A;  1W8O A;  3B7E A;  1X2J A;  2FPB A;  4YW3 A;  1A14 N;  5EX7 A;  2JKB A;  2XCY A;  4XE9 A;  2HT5 A;  1IJQ A;  3WW9 A;  4K1I A;  2FLU X;  3S8V A;  1USR A;  3SAL A;  2YDP A;  1IUC A;  1NCA N;  1L7G A;  2YDT A;  4XJA A;  1IVC A;  4IYG A;  4H53 A;  5FNT A;  1NNA A;  2GVU A;  4YW4 A;  3BYC A;  2IAX A;  4YZ5 A;  1X2R A;  1POO A;  2VK6 A;  4GZQ A;  2VSK A;  4C1Y A;  4K1H A;  2VK5 A;  1MS1 A;  1N1Y A;  2V91 A; 
#chains in the Genus database with same CATH homology
 4MWU A;  1BJI A;  2QWK A;  4XJ8 A;  3D11 A;  4QNP A;  1NMC A;  4FVK A;  4WEG A;  2F26 A;  2HTY A;  4FPG A;  1INH A;  2A75 A;  4B7M A;  3TI5 A;  4MC7 A;  1INY A;  1NNC A;  4MZE A;  2FHR A;  2QWH A;  2F12 A;  2F28 A;  3JU4 A;  2VW2 A;  2AGS A;  2QWE A;  2W38 A;  1V2I A;  1V0F A;  1NSC A;  1S18 A;  1N1Y A;  1EUT A;  1KIT A;  1IVE A;  4KS3 A;  1V0Z A;  1A4Q A;  4FPF A;  4WEF A;  2QWB A;  4HZX A;  4KS5 A;  4MJV A;  2QWJ A;  4DGR A;  3K38 A;  3TI4 A;  4CPL A;  4XJR A;  4M4N A;  2C4A A;  4XHB A;  1NSB A;  2F11 A;  2YA7 A;  5B2D A;  4Q6K A;  4XMI A;  7NN9 A;  1W0P A;  4MWW A;  1USX A;  2BF6 A;  3INB A;  2HTU A;  4FPE A;  3CL2 A;  4FPL A;  1S0I A;  4YZ3 A;  4FOQ A;  4XJZ A;  4QN4 A;  1MS0 A;  1SNT A;  2F10 A;  4FOY A;  4KS1 A;  3T1E A;  5B2C A;  4XHX A;  1L7F A;  4MWV A;  2XZI A;  3OPZ A;  5M1Z A;  4FPO B;  2F0Z A;  4K1K A;  3TIC A;  1W1X A;  4M4U A;  2AEP A;  4GJT A;  4XJQ A;  2BER A;  1Z4V A;  2YA5 A;  3H72 A;  1Z4Z A;  1NSD A;  3BEQ A;  5HUG A;  1Z4Y A;  4MWX A;  5NN9 A;  4WA4 A;  4CPN A;  4QN5 A;  3H73 A;  6NN9 A;  3SAN A;  4UF7 A;  2AH2 A;  2QWI A;  1F8C A;  1NCD N;  4XMA A;  2HTQ A;  4B7R A;  2C4L A;  4XJU A;  1IVF A;  4K3Y A;  4XOG A;  4GZT A;  1V0E A;  2VW1 A;  1DIL A;  4BBW A;  2W5O A;  4XYX A;  1W21 A;  2F13 A;  1W0O A;  4FOV A;  1MS3 A;  2ZB5 A;  1XOG A;  1MS5 A;  1SLL A;  3PJQ A;  4MWQ A;  4I00 A;  4XIL A;  2QWC A;  5HUM A;  4HZW A;  1EUU A;  1IVG A;  1V3C A;  3H6J A;  5HUN A;  4CPO A;  1EUR A;  4MWJ A;  5F9T A;  2BAT A;  1F8D A;  2VSM A;  1W20 A;  3W09 A;  4MWR A;  1W8N A;  3K36 A;  3CYE A;  4KS2 A;  4CPM A;  1DIM A;  3K39 A;  1IVB A;  1F8B A;  4B7N A;  4YZ4 A;  4NCS A;  1MR5 A;  2HT8 A;  2F27 A;  3GVL A;  4FPJ A;  2XZK A;  1E8T A;  4HZV A;  3SIL A;  1E8V A;  1NCC N;  1V3D A;  3TI6 A;  2SLI A;  4MZA A;  2W5N A;  1WCQ A;  1V3B A;  1ING A;  1VCU A;  2QWD A;  2F25 A;  1NCB N;  1E8U A;  1N1T A;  2RKC A;  2B8H A;  4B7Q A;  3H71 A;  2QWG A;  4YZ2 A;  1NMA N;  2BZD A;  4MJU A;  4QN6 A;  4YZ1 A;  1MS9 A;  4K1J A;  3NN9 A;  3TIB A;  1A4G A;  2ZB6 A;  4FOW A;  4GZP A;  2QWA A;  4XIO A;  4GZO A;  4X47 A;  4FPC A;  4QN3 A;  4QN7 A;  4X49 A;  2HTR A;  1MWE A;  1WCS A;  4FP2 A;  1SLI A;  1MS4 A;  1N1V A;  4GB1 A;  3A71 A;  1INF A;  5JYY A;  2F29 A;  4FPH A;  2HU4 A;  1MS8 A;  4HZZ A;  1INV A;  2VK7 A;  4GZS A;  4D8S A;  4GEZ A;  4X6K A;  1F8E A;  2HT7 A;  1NNB A;  4M4V A;  3CL0 A;  2W20 A;  4WA5 A;  3A72 A;  3GVJ A;  2VWD A;  4GDI A;  4FJ6 A;  1Z4W A;  4H52 A;  1B9T A;  3B69 A;  2YA4 A;  3ALW A;  4HZY A;  3K3A A;  4HIZ A;  4YW1 A;  1XOE A;  3O9K A;  4FPY A;  2CML A;  1L7H A;  4MWL A;  4GDJ A;  3TI3 A;  3CKZ A;  1INW A;  4SLI A;  3GVK A;  1Z50 A;  4WA3 A;  4NN9 A;  4GZW A;  2VVZ A;  1N1S A;  2AEQ A;  5HUK A;  3ALX A;  1EUS A;  4NC5 A;  4GZX A;  2YA8 A;  4YW2 A;  1IVD A;  1INX A;  3K37 A;  1VCJ A;  1NN2 A;  2F24 A;  4FZH A;  2X9M A;  1SO7 A;  2QWF A;  2YA6 A;  1B9S A;  3TIA A;  2SIM A;  2SIL A;  4M3M A;  1S0J A;  4CPY A;  3O9J A;  4X4A A;  1NMB N;  4FP3 A;  4CPZ A;  2HU0 A;  3TI8 A;  2VW0 A;  3SLI A;  4XJ9 A;  1B9V A;  2XZJ A;  2H2U A;  3NSS A;  4YW5 A;  4XIK A;  2HTV A;  4B7J A;  4FQ4 A;  1Z4X A;  1V3E A;  4MWY A;  4FPK A;  2H2N A;  1MZ5 A;  4XJW A;  1S1D A;  2HTW A;  4JF7 A;  4KS4 A;  1MZ6 A;  5HX0 A;  3D12 A;  4J9T A;  1W8O A;  3B7E A;  4YW3 A;  1A14 N;  2JKB A;  2XCY A;  4XE9 A;  2HT5 A;  4K1I A;  1USR A;  3SAL A;  2YDP A;  1NCA N;  1L7G A;  2YDT A;  4XJA A;  1IVC A;  4H53 A;  1NNA A;  4YW4 A;  4YZ5 A;  2VK6 A;  4GZQ A;  2VSK A;  4K1H A;  2VK5 A;  1MS1 A;  4MX0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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