1WP5A

Crystal structure of the c-terminal domain of dna topoisomerase iv
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
323
structure length
323
Chain Sequence
MVASEDVIVTVTKDGYVKRTSLRSYAASNGQDFAMKDTDRLLAMLEMNTKDVLLLFTNKGNYLYCPVHELPDIRWKDLGQHIANIIPIDRDEEIIKAIPINDFELNGYFLFVTRNGMVKKTELKHYKAQRYSKPLTGINLKNDDQVVDVHLTDGMNELFLVTHNGYALWFDESEVSIVGVRAAGVKGMNLKEGDYIVSGQLITSKDESIVVATQRGAVKKMKLTEFEKATRAKRGVVILRELKANPHRISGFVVAQDSDTIYLQTEKSFIETIKVGDIRFSDRYSNGSFVLDEEENGRVISVWKVEAEDKTEKLAAALEHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the topoisomerase IV C-terminal domain: a broken beta-propeller implies a role as geometry facilitator in catalysis
pubmed doi rcsb
molecule tags Isomerase
source organism Geobacillus stearothermophilus
molecule keywords topoisomerase IV
total genus 82
structure length 323
sequence length 323
ec nomenclature ec 5.99.1.-:
pdb deposition date 2004-08-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.90 Mainly Beta 6 Propeller Neuraminidase DNA gyrase/topoisomerase IV, subunit A, C-terminal 1wp5A00
3L6VA 4G3NA 1WP5A 3UC1A 3NO0A 1SUUA 1ZI0A
chains in the Genus database with same CATH superfamily
1IVCA 4FOQA 1NN2A 1INYA 2BATA 3A72A 3H72A 1N1YA 4YW2A 3LI5A 4Q1UA 2DSOA 2C4LA 3PJQA 2HTYA 5HX0A 4MWJA 1V3BA 4NC5A 3K3AA 1S18A 2F27A 5FNUA 3SRGA 1RWIA 1NMBN 3O9JA 2IAQA 4QN5A 2YA7A 3S8VA 3TIBA 2GVUA 2BZDA 1V04A 2OJHA 1EUUA 2QWEA 1INFA 2FP8A 4XHBA 3NO0A 4MJUA 1V2IA 4K1KA 4ZY3A 3TI6A 3O4PA 2B8HA 2W20A 2XZIA 3V64C 4FPYA 2VAQA 2YDPA 4GZQA 2YDTA 5GX5A 4M4VA 3TICA 1MWEA 1E1AA 2H2UA 2JKBA 4B7MA 4CPMA 1Z50A 4GNCA 5HUKA 1PJXA 3SOQA 2QWIA 4XHXA 2VSKA 5H47A 4GZSA 1B9TA 1NSBA 4XJAA 3HLIA 4GZTA 1C9UA 4M3MA 4X47A 4YZ4A 1B9VA 3GVLA 1DIMA 2F29A 2IAUA 2DG0A 2A75A 2FLUX 1MS0A 1NPEA 2DG1A 1MR5A 2QWDA 5CGJA 1ZI0A 4IMBA 1Z4XA 4D52B 4N1BA 3V1SA 4DG6A 3A9GA 2VK7A 4FPOB 3D11A 1EUSA 5FNRA 1Q7FA 4XJRA 1S0IA 1E8UA 3H71A 3II7A 5F72C 4HHQA 2F25A 4L7CA 4XIKA 4FOWA 1N7DA 4CPLA 3LI4A 3SOBB 1N6DA 4GN8A 4FPCA 3K38A 1L7GA 3AMSA 1MS1A 1IUBA 1X2JA 3NSSA 4O5TA 2HTUA 3ADEA 4B7JA 4FOVA 5D9DA 3O9KA 2H2NA 2QWHA 4Q6KA 4BBWA 2AH2A 2ZZKA 5D9CA 1N6FA 2HT5A 4FPLA 1N6EA 2ZB5A 4IYGA 3SANA 4K1IA 4L7DA 5JYYA 1SNTA 2IAPA 1H6LA 2V91A 2HQSA 2ZW9A 4D8SA 1INGA 2RKCA 1N1SA 1K32A 1EUTA 2F24A 3K39A 2XCYA 4XJQA 2CMLA 1USRA 5NN9A 1NMAN 2BERA 1L7FA 1INWA 2YA6A 4WA3A 2XN4A 2G8SA 1L7HA 4MWVA 2W5OA 1U6DX 4FPKA 4QN3A 1IVEA 2F26A 2AGSA 3TI3A 3IAXA 1X2RA 4KS4A 3H73A 3SLIA 3WDZA 2HT7A 3E5ZA 4CPZA 2VPJA 3A71A 1F8DA 4C1YB 1NMCA 4MWLA 4GEZA 2P4OA 1SLIA 1MS9A 1W20A 1INXA 2VVZA 2F12A 4KS2A 3HLHA 4XMIA 3L6VA 4FPEA 3KYAA 3U0SA 4X49A 3TI4A 2HTQA 4IFLX 4XJUA 3S2KA 2FHRA 1B9SA 2F10A 3B69A 4GNAA 4WA5A 4A0PA 4IN4A 3ALXA 4YW3A 4J9TA 2XZJA 4CHBA 4PWZA 4FOYA 4G3NA 4FP3A 4HIZA 4O5SA 4HZXA 3CYEA 4WEGA 2BF6A 2FPBA 4HZYA 4C1YA 3SOVA 1Z4WA 4MC7A 4XYXA 2AEPA 1CRUA 2QWGA 3T1EA 1KITA 4FPJA 1CVMA 1INHA 5FNTA 2XZKA 3Q6PA 4MWQA 2GVVA 3OPZA 1WCSA 3AMRA 2C4AA 3A9HA 2X9MA 4FPHA 3BYCA 3VNGA 4L7BA 2Z32A 4HZWA 1QBIA 3SILA 1XOGA 4KS3A 3ZGCA 1A14N 3JU4A 1IVGA 4XILA 5FNSA 1NNBA 1N1VA 1RWLA 4GB1A 3ZGDA 1W8NA 4DGRA 2IAOA 3TC9A 3DASA 3DR2A 5B2CA 1A4QA 4X6KA 1OFZA 4FQ4A 4HZVA 4GZOA 4FVKA 4XJ8A 4WA4A 4UOUA 2IAWA 4SLIA 2FPCA 3G4EA 4D52A 4XMBA 1V3DA 5GX2A 1C5KA 1VCJA 3K36A 2W5NA 3V65B 3W09A 1QLGA 2IAXA 2GVWA 4JF7A 1MS5A 4H52A 2IATA 4MZEA 1W0OA 1SO7A 5B2DA 4ZGCA 2HT8A 4QNPA 4XJ9A 4XJZA 1NCCN 4YZ2A 4HHOA 2IARA 4QN7A 4FP2A 2F11A 2YA4A 1V0EA 3CKZA 4QN4A 3Q6TA 1NSDA 3SALA 4AGTA 3H6JA 2QWJA 4HW6A 4IFJA 3Q6KA 2SILA 2F0ZA 2QE8A 3P5BL 1IVFA 4YW5A 3FVZA 2SIMA 4YW4A 3HRPA 4MWRA 1N1TA 1NNCA 1V0ZA 1V3CA 2VK5A 4X4AA 3CL0A 3TIAA 1W1XA 5EO8A 2W38A 2ISMA 4FPGA 2ZWAA 4MX0A 4XIOA 5GX3A 2VSMA 3G4HA 4ZLRA 2QWFA 1WP5A 4CPYA 2HTRA 1E8VA 4MWYA 1IVDA 4WEFA 2FP9A 1CRZA 1MS4A 2IASA 7NN9A 2YA8A 4R40A 1E8TA 4XMAA 1F8EA 4YW1A 4GDJA 3UC1A 1V3EA 2HTWA 3GVKA 4GN9A 3WWAA 2IVZA 3GVJA 4FPFA 3B7EA 3ALWA 2QWAA 4I00A 5D9BA 1IUCA 1SLLA 4MZAA 1Z4ZA 1ZGKA 2GVXA 2SLIA 4GZWA 2GHSA 4ASCA 1MS8A 4YZ1A 3NN9A 4NN9A 1NNAA 2HU4A 1USXA 1BJIA 2QWBA 1XOEA 4B7NA 4YZ3A 3SREA 5EO7A 1IVBA 2IAVA 4MWXA 4CH9A 2W8BB 5FNQA 5EX7A 2QWCA 3LI3A 4KS5A 4MWUA 5FZNA 5GTQA 4YY8A 5F9TA 2VK6A 4MJVA 4B7QA 1INVA 4HZZA 1F8BA 5GX4A 4KS1A 1IJQA 2VW0A 1Z4VA 4K3YA 4GZXA 4AHAA 1MZ6A 4FJ6A 5GX1A 4QN6A 3S94A 4NCSA 1MZ5A 2VW1A 2YA5A 4AH4A 4MWWA 4K1HA 5M1ZA 5HUNA 3TI8A 1MS3A 5HUMA 4H53A 2F28A 2F13A 3WW9A 4CSDA 2POOA 1S1DA 1W21A 1V0FA 5FZJA 1W0PA 2ZB6A 4M4NA 4GDIA 4XE9A 3K37A 4GNBA 2W8BA 2HU0A 2HTVA 3S8ZA 2DYHA 4FZHA 2QWKA 4XOGA 1SUUA 1NCAN 4B7RA 5HUGA 4CPNA 1NCBN 3I1CA 1A4GA 3FW0A 3BEQA 1W8OA 4AGIA 1CQ1A 4K1JA 4M4UA 4D52C 1S0JA 3KGGA 1POOA 4YZ5A 6NN9A 1F8CA 1VCUA 1DILA 4GJTA 4D4UA 4JMLA 5FWWA 4GN7A 3D12A 3CL2A 3VNHA 1NCDN 4UF7A 4IQKA 3WN7A 2AEQA 2WOZA 2VWDA 2VW2A 1NSCA 3TI5A 4CPOA 4IFNX 1EURA 3INBA 1WCQA 4GZPA 4XJWA 1Z4YA
chains in the Genus database with same CATH topology
3L6VA 4G3NA 1WP5A 3UC1A 3NO0A 1SUUA 1ZI0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3L6V A;  4G3N A;  1WP5 A;  3UC1 A;  3NO0 A;  1SUU A;  1ZI0 A; 
#chains in the Genus database with same CATH topology
 1IVC A;  4FOQ A;  1NN2 A;  1INY A;  2BAT A;  3A72 A;  3H72 A;  1N1Y A;  4YW2 A;  3LI5 A;  4Q1U A;  2DSO A;  2C4L A;  3PJQ A;  2HTY A;  5HX0 A;  4MWJ A;  1V3B A;  4NC5 A;  3K3A A;  1S18 A;  2F27 A;  5FNU A;  3SRG A;  1RWI A;  1NMB N;  3O9J A;  2IAQ A;  4QN5 A;  2YA7 A;  3S8V A;  3TIB A;  2GVU A;  2BZD A;  1V04 A;  2OJH A;  1EUU A;  2QWE A;  1INF A;  2FP8 A;  4XHB A;  3NO0 A;  4MJU A;  1V2I A;  4K1K A;  4ZY3 A;  3TI6 A;  3O4P A;  2B8H A;  2W20 A;  2XZI A;  3V64 C;  4FPY A;  2VAQ A;  2YDP A;  4GZQ A;  2YDT A;  5GX5 A;  4M4V A;  3TIC A;  1MWE A;  1E1A A;  2H2U A;  2JKB A;  4B7M A;  4CPM A;  1Z50 A;  4GNC A;  5HUK A;  1PJX A;  3SOQ A;  2QWI A;  4XHX A;  2VSK A;  5H47 A;  4GZS A;  1B9T A;  1NSB A;  4XJA A;  3HLI A;  4GZT A;  1C9U A;  4M3M A;  4X47 A;  4YZ4 A;  1B9V A;  3GVL A;  1DIM A;  2F29 A;  2IAU A;  2DG0 A;  2A75 A;  2FLU X;  1MS0 A;  1NPE A;  2DG1 A;  1MR5 A;  2QWD A;  5CGJ A;  1ZI0 A;  4IMB A;  1Z4X A;  4D52 B;  4N1B A;  3V1S A;  4DG6 A;  3A9G A;  2VK7 A;  4FPO B;  3D11 A;  1EUS A;  5FNR A;  1Q7F A;  4XJR A;  1S0I A;  1E8U A;  3H71 A;  3II7 A;  5F72 C;  4HHQ A;  2F25 A;  4L7C A;  4XIK A;  4FOW A;  1N7D A;  4CPL A;  3LI4 A;  3SOB B;  1N6D A;  4GN8 A;  4FPC A;  3K38 A;  1L7G A;  3AMS A;  1MS1 A;  1IUB A;  1X2J A;  3NSS A;  4O5T A;  2HTU A;  3ADE A;  4B7J A;  4FOV A;  5D9D A;  3O9K A;  2H2N A;  2QWH A;  4Q6K A;  4BBW A;  2AH2 A;  2ZZK A;  5D9C A;  1N6F A;  2HT5 A;  4FPL A;  1N6E A;  2ZB5 A;  4IYG A;  3SAN A;  4K1I A;  4L7D A;  5JYY A;  1SNT A;  2IAP A;  1H6L A;  2V91 A;  2HQS A;  2ZW9 A;  4D8S A;  1ING A;  2RKC A;  1N1S A;  1K32 A;  1EUT A;  2F24 A;  3K39 A;  2XCY A;  4XJQ A;  2CML A;  1USR A;  5NN9 A;  1NMA N;  2BER A;  1L7F A;  1INW A;  2YA6 A;  4WA3 A;  2XN4 A;  2G8S A;  1L7H A;  4MWV A;  2W5O A;  1U6D X;  4FPK A;  4QN3 A;  1IVE A;  2F26 A;  2AGS A;  3TI3 A;  3IAX A;  1X2R A;  4KS4 A;  3H73 A;  3SLI A;  3WDZ A;  2HT7 A;  3E5Z A;  4CPZ A;  2VPJ A;  3A71 A;  1F8D A;  4C1Y B;  1NMC A;  4MWL A;  4GEZ A;  2P4O A;  1SLI A;  1MS9 A;  1W20 A;  1INX A;  2VVZ A;  2F12 A;  4KS2 A;  3HLH A;  4XMI A;  3L6V A;  4FPE A;  3KYA A;  3U0S A;  4X49 A;  3TI4 A;  2HTQ A;  4IFL X;  4XJU A;  3S2K A;  2FHR A;  1B9S A;  2F10 A;  3B69 A;  4GNA A;  4WA5 A;  4A0P A;  4IN4 A;  3ALX A;  4YW3 A;  4J9T A;  2XZJ A;  4CHB A;  4PWZ A;  4FOY A;  4G3N A;  4FP3 A;  4HIZ A;  4O5S A;  4HZX A;  3CYE A;  4WEG A;  2BF6 A;  2FPB A;  4HZY A;  4C1Y A;  3SOV A;  1Z4W A;  4MC7 A;  4XYX A;  2AEP A;  1CRU A;  2QWG A;  3T1E A;  1KIT A;  4FPJ A;  1CVM A;  1INH A;  5FNT A;  2XZK A;  3Q6P A;  4MWQ A;  2GVV A;  3OPZ A;  1WCS A;  3AMR A;  2C4A A;  3A9H A;  2X9M A;  4FPH A;  3BYC A;  3VNG A;  4L7B A;  2Z32 A;  4HZW A;  1QBI A;  3SIL A;  1XOG A;  4KS3 A;  3ZGC A;  1A14 N;  3JU4 A;  1IVG A;  4XIL A;  5FNS A;  1NNB A;  1N1V A;  1RWL A;  4GB1 A;  3ZGD A;  1W8N A;  4DGR A;  2IAO A;  3TC9 A;  3DAS A;  3DR2 A;  5B2C A;  1A4Q A;  4X6K A;  1OFZ A;  4FQ4 A;  4HZV A;  4GZO A;  4FVK A;  4XJ8 A;  4WA4 A;  4UOU A;  2IAW A;  4SLI A;  2FPC A;  3G4E A;  4D52 A;  4XMB A;  1V3D A;  5GX2 A;  1C5K A;  1VCJ A;  3K36 A;  2W5N A;  3V65 B;  3W09 A;  1QLG A;  2IAX A;  2GVW A;  4JF7 A;  1MS5 A;  4H52 A;  2IAT A;  4MZE A;  1W0O A;  1SO7 A;  5B2D A;  4ZGC A;  2HT8 A;  4QNP A;  4XJ9 A;  4XJZ A;  1NCC N;  4YZ2 A;  4HHO A;  2IAR A;  4QN7 A;  4FP2 A;  2F11 A;  2YA4 A;  1V0E A;  3CKZ A;  4QN4 A;  3Q6T A;  1NSD A;  3SAL A;  4AGT A;  3H6J A;  2QWJ A;  4HW6 A;  4IFJ A;  3Q6K A;  2SIL A;  2F0Z A;  2QE8 A;  3P5B L;  1IVF A;  4YW5 A;  3FVZ A;  2SIM A;  4YW4 A;  3HRP A;  4MWR A;  1N1T A;  1NNC A;  1V0Z A;  1V3C A;  2VK5 A;  4X4A A;  3CL0 A;  3TIA A;  1W1X A;  5EO8 A;  2W38 A;  2ISM A;  4FPG A;  2ZWA A;  4MX0 A;  4XIO A;  5GX3 A;  2VSM A;  3G4H A;  4ZLR A;  2QWF A;  1WP5 A;  4CPY A;  2HTR A;  1E8V A;  4MWY A;  1IVD A;  4WEF A;  2FP9 A;  1CRZ A;  1MS4 A;  2IAS A;  7NN9 A;  2YA8 A;  4R40 A;  1E8T A;  4XMA A;  1F8E A;  4YW1 A;  4GDJ A;  3UC1 A;  1V3E A;  2HTW A;  3GVK A;  4GN9 A;  3WWA A;  2IVZ A;  3GVJ A;  4FPF A;  3B7E A;  3ALW A;  2QWA A;  4I00 A;  5D9B A;  1IUC A;  1SLL A;  4MZA A;  1Z4Z A;  1ZGK A;  2GVX A;  2SLI A;  4GZW A;  2GHS A;  4ASC A;  1MS8 A;  4YZ1 A;  3NN9 A;  4NN9 A;  1NNA A;  2HU4 A;  1USX A;  1BJI A;  2QWB A;  1XOE A;  4B7N A;  4YZ3 A;  3SRE A;  5EO7 A;  1IVB A;  2IAV A;  4MWX A;  4CH9 A;  2W8B B;  5FNQ A;  5EX7 A;  2QWC A;  3LI3 A;  4KS5 A;  4MWU A;  5FZN A;  5GTQ A;  4YY8 A;  5F9T A;  2VK6 A;  4MJV A;  4B7Q A;  1INV A;  4HZZ A;  1F8B A;  5GX4 A;  4KS1 A;  1IJQ A;  2VW0 A;  1Z4V A;  4K3Y A;  4GZX A;  4AHA A;  1MZ6 A;  4FJ6 A;  5GX1 A;  4QN6 A;  3S94 A;  4NCS A;  1MZ5 A;  2VW1 A;  2YA5 A;  4AH4 A;  4MWW A;  4K1H A;  5M1Z A;  5HUN A;  3TI8 A;  1MS3 A;  5HUM A;  4H53 A;  2F28 A;  2F13 A;  3WW9 A;  4CSD A;  2POO A;  1S1D A;  1W21 A;  1V0F A;  5FZJ A;  1W0P A;  2ZB6 A;  4M4N A;  4GDI A;  4XE9 A;  3K37 A;  4GNB A;  2W8B A;  2HU0 A;  2HTV A;  3S8Z A;  2DYH A;  4FZH A;  2QWK A;  4XOG A;  1SUU A;  1NCA N;  4B7R A;  5HUG A;  4CPN A;  1NCB N;  3I1C A;  1A4G A;  3FW0 A;  3BEQ A;  1W8O A;  4AGI A;  1CQ1 A;  4K1J A;  4M4U A;  4D52 C;  1S0J A;  3KGG A;  1POO A;  4YZ5 A;  6NN9 A;  1F8C A;  1VCU A;  1DIL A;  4GJT A;  4D4U A;  4JML A;  5FWW A;  4GN7 A;  3D12 A;  3CL2 A;  3VNH A;  1NCD N;  4UF7 A;  4IQK A;  3WN7 A;  2AEQ A;  2WOZ A;  2VWD A;  2VW2 A;  1NSC A;  3TI5 A;  4CPO A;  4IFN X;  1EUR A;  3INB A;  1WCQ A;  4GZP A;  4XJW A;  1Z4Y A; 
#chains in the Genus database with same CATH homology
 3L6V A;  4G3N A;  1WP5 A;  3UC1 A;  3NO0 A;  1SUU A;  1ZI0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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