2F13A

Crystal structure of the human sialidase neu2 in complex with 2',3'- dihydroxypropyl ether mimetic inhibitor
Total Genus 90
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
374
structure length
351
Chain Sequence
SLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRAAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLNDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVEEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Human Sialidase Neu2 in Complex with 2',3'- dihydroxypropyl ether mimetic Inhibitor
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Sialidase 2
total genus 90
structure length 351
sequence length 374
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2005-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13088 BNR_2 BNR repeat-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 2f13A00
2W5OA 3H6JA 7NN9A 1Z4WA 4WEFA 2F13A 1WCSA 4QN3A 1L7HA 4XIOA 2HT5A 4FPGA 3CL2A 5F9TA 2AH2A 4B7RA 2YA7A 2XZJA 4XHXA 4MZEA 4GZXA 2F0ZA 4QN4A 2YA6A 4XJ9A 2JKBA 1S0JA 4KS2A 5JYYA 3SLIA 1MR5A 2F10A 4FZHA 2W20A 1N1YA 4YZ4A 4KS4A 2VW2A 1SO7A 4XIKA 2AEQA 3NSSA 1NCAN 3O9KA 2BERA 2QWAA 1KITA 4HZXA 2YDPA 5HUMA 2X9MA 1INFA 1IVDA 1NMBN 1N1TA 1MS4A 1SLIA 4KS1A 4FP3A 4MWQA 1USRA 1N1VA 3O9JA 4FP2A 4GZOA 4FOVA 4GZPA 4XMAA 1W0PA 4WEGA 1L7GA 4FPOB 2C4LA 1EUSA 3K39A 1MS8A 4HZVA 4QN6A 1W0OA 5NN9A 4FVKA 2HTRA 4X6KA 4MWYA 1S0IA 3SALA 2HTUA 1EUUA 3INBA 4XMIA 2F26A 1INVA 3W09A 4FOYA 3BEQA 4CPOA 1NCBN 1DILA 3K37A 1MZ6A 4XJ8A 1A4GA 4XJZA 1V3DA 1IVEA 2SLIA 1MS3A 4M4VA 4M4UA 1WCQA 5HUNA 4MWLA 1V3CA 1SNTA 5B2CA 4FQ4A 2AGSA 4M4NA 1Z4XA 3TI5A 4GEZA 2F24A 3JU4A 1F8BA 4KS3A 1Z4YA 4DGRA 2YDTA 2AEPA 4GJTA 4YW5A 3TICA 4XHBA 2F28A 4MWWA 4YZ3A 4MX0A 2HT7A 3TI6A 2F25A 1IVFA 4BBWA 2W38A 4XJWA 4FOWA 3ALXA 1V3EA 1A4QA 1NCCN 4MJVA 4K1KA 1MWEA 4GZTA 1V3BA 2VSKA 2ZB6A 3TI3A 2HU4A 2HT8A 2QWBA 1Z4VA 2VK5A 1Z50A 2QWKA 4J9TA 4XOGA 4X4AA 2BZDA 4I00A 6NN9A 4GDJA 4GZQA 2YA4A 2RKCA 4FPHA 2YA8A 4CPMA 4K1HA 1EURA 1V0EA 3CYEA 4FPJA 2F12A 4X49A 4XJRA 4H52A 1INYA 4NC5A 1F8EA 4YW2A 4YW3A 2HU0A 5HUKA 1V0ZA 1A14N 1E8VA 4FJ6A 4YW1A 2XCYA 4B7JA 3SANA 4WA4A 4XE9A 3T1EA 3K36A 2XZKA 1BJIA 4JF7A 2C4AA 1N1SA 2QWDA 1MS9A 4SLIA 2HTWA 4MWXA 4MWVA 2XZIA 5HX0A 4FPCA 1NN2A 2QWCA 3OPZA 2VSMA 2VW0A 3SILA 2QWFA 1INWA 4B7QA 4GDIA 1L7FA 1W1XA 4B7NA 1XOGA 2W5NA 1W21A 4XJQA 2SIMA 2F11A 3K38A 4YZ2A 1W8OA 3H73A 2ZB5A 1USXA 4FPEA 2VW1A 1EUTA 3GVJA 4GB1A 3GVLA 1MS0A 4XILA 2QWHA 2B8HA 4FOQA 3D12A 2F29A 2QWIA 1Z4ZA 2F27A 4MZAA 4UF7A 1IVCA 4HIZA 4YZ5A 4CPLA 3A71A 3TIAA 4K3YA 4MWJA 4WA5A 1NNCA 1NMCA 3K3AA 2SILA 2A75A 4GZWA 4MWRA 3B7EA 4FPFA 4NN9A 1NCDN 2VK7A 3NN9A 5M1ZA 4HZWA 1B9VA 1B9SA 4XJAA 1MS1A 1F8DA 4YW4A 2YA5A 4FPKA 3TI8A 4YZ1A 4FPYA 1NSDA 5HUGA 4QN7A 5B2DA 1V0FA 1W8NA 1E8UA 4WA3A 3H71A 2VK6A 2QWEA 4K1JA 1NNAA 3D11A 1INGA 3B69A 2QWGA 4Q6KA 4MWUA 1IVBA 4CPNA 3H72A 1SLLA 2VVZA 4GZSA 3A72A 1MZ5A 1INHA 4CPZA 1W20A 4CPYA 4QN5A 2CMLA 1V2IA 1B9TA 2BF6A 2FHRA 2HTQA 4HZZA 1NMAN 2HTYA 1NNBA 4FPLA 4X47A 4QNPA 1NSBA 4H53A 3TI4A 3TIBA 1F8CA 1IVGA 1INXA 4NCSA 4KS5A 3ALWA 3CL0A 2VWDA 4K1IA 4XJUA 1MS5A 4MC7A 4HZYA 4M3MA 4MJUA 4XYXA 3CKZA 4B7MA 2HTVA 2BATA 1DIMA 1XOEA 1E8TA 1NSCA 4D8SA 1VCJA 2QWJA 3GVKA 1VCUA 3PJQA
chains in the Genus database with same CATH superfamily
2W5OA 3DR2A 3H6JA 1X2JA 4ZY3A 7NN9A 1Z4WA 1C9UA 4IN4A 4WEFA 2F13A 5FZJA 1WCSA 4QN3A 5FNUA 3Q6PA 5FWWA 1L7HA 2IAPA 4XIOA 2HT5A 4FPGA 1RWLA 2IAOA 3E5ZA 3CL2A 5F9TA 2AH2A 2IAQA 4B7RA 2YA7A 2XZJA 4XHXA 4MZEA 2DG0A 4GZXA 2F0ZA 4QN4A 2YA6A 4XJ9A 2DSOA 2JKBA 3G4EA 1S0JA 1K32A 3II7A 3ZGDA 2VPJA 4KS2A 4GN7A 5JYYA 3AMSA 3SLIA 3V1SA 1MR5A 2F10A 1QBIA 4FZHA 2W20A 3HLHA 1N1YA 4YZ4A 5GX3A 4KS4A 2VW2A 1SO7A 4UOUA 4XIKA 2AEQA 3VNHA 3LI3A 4R40A 3NSSA 1NCAN 3O9KA 2BERA 2QWAA 1KITA 4IQKA 4HZXA 2YDPA 5HUMA 2IARA 4AGTA 2X9MA 1INFA 3SRGA 1IVDA 1NMBN 1N1TA 2GHSA 3V65B 1MS4A 1SLIA 4KS1A 4FP3A 4MWQA 2W8BB 1USRA 1N1VA 2OJHA 3O9JA 2QE8A 5GX1A 4FP2A 4GZPA 4FOVA 4GZOA 4IFNX 4XMAA 3FVZA 3SREA 1W0PA 4WEGA 4GN9A 1L7GA 2IASA 3U0SA 4FPOB 4JMLA 2C4LA 1EUSA 3K39A 1MS8A 4HZVA 4QN6A 3KGGA 1W0OA 4IFJA 5NN9A 2POOA 3Q6TA 4FVKA 5D9CA 2HTRA 4X6KA 4D52A 4MWYA 1S0IA 3SALA 2HTUA 1EUUA 5GX4A 3INBA 4XMIA 2F26A 1INVA 3W09A 4FOYA 3BEQA 4CPOA 1N7DA 1NCBN 1DILA 3S2KA 3K37A 1MZ6A 5CGJA 4XJ8A 1A4GA 4XJZA 1V3DA 1IVEA 5D9BA 2SLIA 5FNTA 1MS3A 2GVUA 4M4VA 4M4UA 1WCQA 5HUNA 1V04A 4MWLA 1H6LA 1V3CA 4HHOA 4N1BA 1SNTA 5B2CA 4FQ4A 5H47A 2AGSA 2IATA 2W8BA 3LI5A 3ADEA 4C1YB 4M4NA 1Z4XA 3TI5A 4GEZA 4D52C 2F24A 3LI4A 3JU4A 3AMRA 4L7BA 1F8BA 4KS3A 1Z4YA 4DGRA 2YDTA 2AEPA 4GJTA 4YW5A 3TICA 4XHBA 2F28A 4MWWA 4D4UA 4DG6A 4YZ3A 4MX0A 4G3NA 2HT7A 3TI6A 2F25A 1IVFA 4BBWA 2W38A 4XJWA 4FOWA 3SOBB 3O4PA 3ALXA 1V3EA 1A4QA 1NCCN 4MJVA 4YY8A 4K1KA 1MWEA 4GZTA 1V3BA 2DG1A 1PJXA 2VSKA 1N6DA 2ZB6A 3TI3A 4CH9A 2HU4A 2HT8A 5EO7A 2QWBA 1Z4VA 2VK5A 2IAXA 3SOQA 2IAVA 1Z50A 5F72C 4IYGA 5EO8A 1IUBA 2QWKA 3WW9A 4J9TA 3DASA 1CVMA 4XOGA 4X4AA 2BZDA 3UC1A 4I00A 6NN9A 4GDJA 4GZQA 2IVZA 2YA4A 4L7CA 2RKCA 4FPHA 2YA8A 4ZLRA 4CPMA 4K1HA 1E1AA 1EURA 1V0EA 3CYEA 4FPJA 3VNGA 2F12A 4GN8A 4X49A 4XJRA 4H52A 5FNQA 1INYA 4NC5A 3A9HA 3BYCA 1F8EA 4YW2A 4YW3A 2Z32A 2HU0A 5GX5A 5HUKA 1V0ZA 1A14N 1E8VA 2V91A 4FJ6A 4YW1A 2XCYA 4B7JA 5D9DA 3S8ZA 3SANA 4WA4A 4XE9A 3T1EA 3K36A 2XZKA 4ASCA 2GVXA 1BJIA 4JF7A 2C4AA 2H2NA 1CRUA 1N1SA 2QWDA 2VAQA 4Q1UA 1MS9A 4SLIA 2H2UA 1SUUA 2HTWA 2DYHA 1S18A 4MWXA 4MWVA 2XZIA 4CSDA 5HX0A 4FPCA 2IAWA 1NN2A 2QWCA 3OPZA 2VSMA 3IAXA 2VW0A 3SILA 2QWFA 1INWA 4B7QA 5FNRA 4XMBA 4GDIA 1L7FA 1W1XA 4B7NA 1XOGA 2W5NA 3WWAA 1W21A 4XJQA 3Q6KA 2SIMA 3I1CA 2FP8A 2F11A 4A0PA 3A9GA 3HRPA 3K38A 2ZWAA 4YZ2A 1W8OA 2FPCA 3H73A 2ZB5A 1USXA 4FPEA 5FZNA 4L7DA 2VW1A 5EX7A 4IFLX 1EUTA 3GVJA 4GB1A 1RWIA 3GVLA 1MS0A 4XILA 2QWHA 2B8HA 4O5SA 1CQ1A 4FOQA 3D12A 2F29A 2QWIA 1Z4ZA 3HLIA 2F27A 4MZAA 4UF7A 3G4HA 1IVCA 4HIZA 4YZ5A 4CPLA 3A71A 3TIAA 4K3YA 4MWJA 4WA5A 2ISMA 1NNCA 1NMCA 4AHAA 3K3AA 2SILA 1WP5A 2A75A 1X2RA 4GZWA 3ZGCA 4MWRA 3B7EA 4FPFA 4NN9A 3S94A 1NCDN 2VK7A 4C1YA 1S1DA 3NN9A 5M1ZA 3NO0A 4HZWA 1B9VA 1B9SA 4XJAA 3TC9A 1MS1A 1F8DA 4YW4A 3P5BL 1ZI0A 2YA5A 4FPKA 3TI8A 1N6FA 1IJQA 4YZ1A 4FPYA 1NSDA 5HUGA 4QN7A 5B2DA 4D52B 1V0FA 1W8NA 2GVVA 1E8UA 2FPBA 4WA3A 3H71A 2VK6A 2QWEA 4CHBA 1ZGKA 5GTQA 4K1JA 1NNAA 3D11A 2FLUX 1INGA 2GVWA 3B69A 2P4OA 2IAUA 2QWGA 4Q6KA 2ZW9A 4GNBA 4MWUA 4GNAA 1IVBA 4CPNA 3H72A 2FP9A 3KYAA 1SLLA 4AGIA 2VVZA 4GZSA 4GNCA 1NPEA 2WOZA 3A72A 1POOA 1MZ5A 1IUCA 1Q7FA 1CRZA 1OFZA 3L6VA 1INHA 4CPZA 4HHQA 4ZGCA 1W20A 4CPYA 4QN5A 2CMLA 1V2IA 1B9TA 2BF6A 2FHRA 2HTQA 4HZZA 1NMAN 5GX2A 2HTYA 1NNBA 4FPLA 4X47A 4QNPA 3WN7A 1NSBA 4H53A 5FNSA 3TI4A 3TIBA 4O5TA 4HW6A 1F8CA 1IVGA 1INXA 3FW0A 4NCSA 4KS5A 3ALWA 3CL0A 2VWDA 4PWZA 4K1IA 4XJUA 4AH4A 1MS5A 3WDZA 2ZZKA 4IMBA 4MC7A 4HZYA 4M3MA 1N6EA 4MJUA 4XYXA 3CKZA 4B7MA 2HTVA 2BATA 1DIMA 3V64C 1XOEA 1U6DX 1E8TA 1QLGA 2G8SA 1C5KA 1NSCA 3S8VA 1VCJA 2QWJA 2XN4A 4D8SA 2HQSA 3GVKA 3SOVA 1VCUA 3PJQA
chains in the Genus database with same CATH topology
2W5OA 3H6JA 7NN9A 1Z4WA 4WEFA 2F13A 1WCSA 4QN3A 1L7HA 4XIOA 2HT5A 4FPGA 3CL2A 5F9TA 2AH2A 4B7RA 2YA7A 2XZJA 4XHXA 4MZEA 4GZXA 2F0ZA 4QN4A 2YA6A 4XJ9A 2JKBA 1S0JA 4KS2A 5JYYA 3SLIA 1MR5A 2F10A 4FZHA 2W20A 1N1YA 4YZ4A 4KS4A 2VW2A 1SO7A 4XIKA 2AEQA 3NSSA 1NCAN 3O9KA 2BERA 2QWAA 1KITA 4HZXA 2YDPA 5HUMA 2X9MA 1INFA 1IVDA 1NMBN 1N1TA 1MS4A 1SLIA 4KS1A 4FP3A 4MWQA 1USRA 1N1VA 3O9JA 4FP2A 4GZOA 4FOVA 4GZPA 4XMAA 1W0PA 4WEGA 1L7GA 4FPOB 2C4LA 1EUSA 3K39A 1MS8A 4HZVA 4QN6A 1W0OA 5NN9A 4FVKA 2HTRA 4X6KA 4MWYA 1S0IA 3SALA 2HTUA 1EUUA 3INBA 4XMIA 2F26A 1INVA 3W09A 4FOYA 3BEQA 4CPOA 1NCBN 1DILA 3K37A 1MZ6A 4XJ8A 1A4GA 4XJZA 1V3DA 1IVEA 2SLIA 1MS3A 4M4VA 4M4UA 1WCQA 5HUNA 4MWLA 1V3CA 1SNTA 5B2CA 4FQ4A 2AGSA 4M4NA 1Z4XA 3TI5A 4GEZA 2F24A 3JU4A 1F8BA 4KS3A 1Z4YA 4DGRA 2YDTA 2AEPA 4GJTA 4YW5A 3TICA 4XHBA 2F28A 4MWWA 4YZ3A 4MX0A 2HT7A 3TI6A 2F25A 1IVFA 4BBWA 2W38A 4XJWA 4FOWA 3ALXA 1V3EA 1A4QA 1NCCN 4MJVA 4K1KA 1MWEA 4GZTA 1V3BA 2VSKA 2ZB6A 3TI3A 2HU4A 2HT8A 2QWBA 1Z4VA 2VK5A 1Z50A 2QWKA 4J9TA 4XOGA 4X4AA 2BZDA 4I00A 6NN9A 4GDJA 4GZQA 2YA4A 2RKCA 4FPHA 2YA8A 4CPMA 4K1HA 1EURA 1V0EA 3CYEA 4FPJA 2F12A 4X49A 4XJRA 4H52A 1INYA 4NC5A 1F8EA 4YW2A 4YW3A 2HU0A 5HUKA 1V0ZA 1A14N 1E8VA 4FJ6A 4YW1A 2XCYA 4B7JA 3SANA 4WA4A 4XE9A 3T1EA 3K36A 2XZKA 1BJIA 4JF7A 2C4AA 2H2NA 1N1SA 2QWDA 1MS9A 4SLIA 2H2UA 2HTWA 1S18A 4MWXA 4MWVA 2XZIA 5HX0A 4FPCA 1NN2A 2QWCA 3OPZA 2VSMA 2VW0A 3SILA 2QWFA 1INWA 4B7QA 4GDIA 1L7FA 1W1XA 4B7NA 1XOGA 2W5NA 1W21A 4XJQA 2SIMA 2F11A 3K38A 4YZ2A 1W8OA 3H73A 2ZB5A 1USXA 4FPEA 2VW1A 1EUTA 3GVJA 4GB1A 3GVLA 1MS0A 4XILA 2QWHA 2B8HA 4FOQA 3D12A 2F29A 2QWIA 1Z4ZA 2F27A 4MZAA 4UF7A 1IVCA 4HIZA 4YZ5A 4CPLA 3A71A 3TIAA 4K3YA 4MWJA 4WA5A 1NNCA 1NMCA 3K3AA 2SILA 2A75A 4GZWA 4MWRA 3B7EA 4FPFA 4NN9A 1NCDN 2VK7A 1S1DA 3NN9A 5M1ZA 4HZWA 1B9VA 1B9SA 4XJAA 1MS1A 1F8DA 4YW4A 2YA5A 4FPKA 3TI8A 4YZ1A 4FPYA 1NSDA 5HUGA 4QN7A 5B2DA 1V0FA 1W8NA 1E8UA 4WA3A 3H71A 2VK6A 2QWEA 4K1JA 1NNAA 3D11A 1INGA 3B69A 2QWGA 4Q6KA 4MWUA 1IVBA 4CPNA 3H72A 1SLLA 2VVZA 4GZSA 3A72A 1MZ5A 1INHA 4CPZA 1W20A 4CPYA 4QN5A 2CMLA 1V2IA 1B9TA 2BF6A 2FHRA 2HTQA 4HZZA 1NMAN 2HTYA 1NNBA 4FPLA 4X47A 4QNPA 1NSBA 4H53A 3TI4A 3TIBA 1F8CA 1IVGA 1INXA 4NCSA 4KS5A 3ALWA 3CL0A 2VWDA 4K1IA 4XJUA 1MS5A 4MC7A 4HZYA 4M3MA 4MJUA 4XYXA 3CKZA 4B7MA 2HTVA 2BATA 1DIMA 1XOEA 1E8TA 1NSCA 4D8SA 1VCJA 2QWJA 3GVKA 1VCUA 3PJQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W5O A;  3H6J A;  7NN9 A;  1Z4W A;  4WEF A;  2F13 A;  1WCS A;  4QN3 A;  1L7H A;  4XIO A;  2HT5 A;  4FPG A;  3CL2 A;  5F9T A;  2AH2 A;  4B7R A;  2YA7 A;  2XZJ A;  4XHX A;  4MZE A;  4GZX A;  2F0Z A;  4QN4 A;  2YA6 A;  4XJ9 A;  2JKB A;  1S0J A;  4KS2 A;  5JYY A;  3SLI A;  1MR5 A;  2F10 A;  4FZH A;  2W20 A;  1N1Y A;  4YZ4 A;  4KS4 A;  2VW2 A;  1SO7 A;  4XIK A;  2AEQ A;  3NSS A;  1NCA N;  3O9K A;  2BER A;  2QWA A;  1KIT A;  4HZX A;  2YDP A;  5HUM A;  2X9M A;  1INF A;  1IVD A;  1NMB N;  1N1T A;  1MS4 A;  1SLI A;  4KS1 A;  4FP3 A;  4MWQ A;  1USR A;  1N1V A;  3O9J A;  4FP2 A;  4GZO A;  4FOV A;  4GZP A;  4XMA A;  1W0P A;  4WEG A;  1L7G A;  4FPO B;  2C4L A;  1EUS A;  3K39 A;  1MS8 A;  4HZV A;  4QN6 A;  1W0O A;  5NN9 A;  4FVK A;  2HTR A;  4X6K A;  4MWY A;  1S0I A;  3SAL A;  2HTU A;  1EUU A;  3INB A;  4XMI A;  2F26 A;  1INV A;  3W09 A;  4FOY A;  3BEQ A;  4CPO A;  1NCB N;  1DIL A;  3K37 A;  1MZ6 A;  4XJ8 A;  1A4G A;  4XJZ A;  1V3D A;  1IVE A;  2SLI A;  1MS3 A;  4M4V A;  4M4U A;  1WCQ A;  5HUN A;  4MWL A;  1V3C A;  1SNT A;  5B2C A;  4FQ4 A;  2AGS A;  4M4N A;  1Z4X A;  3TI5 A;  4GEZ A;  2F24 A;  3JU4 A;  1F8B A;  4KS3 A;  1Z4Y A;  4DGR A;  2YDT A;  2AEP A;  4GJT A;  4YW5 A;  3TIC A;  4XHB A;  2F28 A;  4MWW A;  4YZ3 A;  4MX0 A;  2HT7 A;  3TI6 A;  2F25 A;  1IVF A;  4BBW A;  2W38 A;  4XJW A;  4FOW A;  3ALX A;  1V3E A;  1A4Q A;  1NCC N;  4MJV A;  4K1K A;  1MWE A;  4GZT A;  1V3B A;  2VSK A;  2ZB6 A;  3TI3 A;  2HU4 A;  2HT8 A;  2QWB A;  1Z4V A;  2VK5 A;  1Z50 A;  2QWK A;  4J9T A;  4XOG A;  4X4A A;  2BZD A;  4I00 A;  6NN9 A;  4GDJ A;  4GZQ A;  2YA4 A;  2RKC A;  4FPH A;  2YA8 A;  4CPM A;  4K1H A;  1EUR A;  1V0E A;  3CYE A;  4FPJ A;  2F12 A;  4X49 A;  4XJR A;  4H52 A;  1INY A;  4NC5 A;  1F8E A;  4YW2 A;  4YW3 A;  2HU0 A;  5HUK A;  1V0Z A;  1A14 N;  1E8V A;  4FJ6 A;  4YW1 A;  2XCY A;  4B7J A;  3SAN A;  4WA4 A;  4XE9 A;  3T1E A;  3K36 A;  2XZK A;  1BJI A;  4JF7 A;  2C4A A;  1N1S A;  2QWD A;  1MS9 A;  4SLI A;  2HTW A;  4MWX A;  4MWV A;  2XZI A;  5HX0 A;  4FPC A;  1NN2 A;  2QWC A;  3OPZ A;  2VSM A;  2VW0 A;  3SIL A;  2QWF A;  1INW A;  4B7Q A;  4GDI A;  1L7F A;  1W1X A;  4B7N A;  1XOG A;  2W5N A;  1W21 A;  4XJQ A;  2SIM A;  2F11 A;  3K38 A;  4YZ2 A;  1W8O A;  3H73 A;  2ZB5 A;  1USX A;  4FPE A;  2VW1 A;  1EUT A;  3GVJ A;  4GB1 A;  3GVL A;  1MS0 A;  4XIL A;  2QWH A;  2B8H A;  4FOQ A;  3D12 A;  2F29 A;  2QWI A;  1Z4Z A;  2F27 A;  4MZA A;  4UF7 A;  1IVC A;  4HIZ A;  4YZ5 A;  4CPL A;  3A71 A;  3TIA A;  4K3Y A;  4MWJ A;  4WA5 A;  1NNC A;  1NMC A;  3K3A A;  2SIL A;  2A75 A;  4GZW A;  4MWR A;  3B7E A;  4FPF A;  4NN9 A;  1NCD N;  2VK7 A;  3NN9 A;  5M1Z A;  4HZW A;  1B9V A;  1B9S A;  4XJA A;  1MS1 A;  1F8D A;  4YW4 A;  2YA5 A;  4FPK A;  3TI8 A;  4YZ1 A;  4FPY A;  1NSD A;  5HUG A;  4QN7 A;  5B2D A;  1V0F A;  1W8N A;  1E8U A;  4WA3 A;  3H71 A;  2VK6 A;  2QWE A;  4K1J A;  1NNA A;  3D11 A;  1ING A;  3B69 A;  2QWG A;  4Q6K A;  4MWU A;  1IVB A;  4CPN A;  3H72 A;  1SLL A;  2VVZ A;  4GZS A;  3A72 A;  1MZ5 A;  1INH A;  4CPZ A;  1W20 A;  4CPY A;  4QN5 A;  2CML A;  1V2I A;  1B9T A;  2BF6 A;  2FHR A;  2HTQ A;  4HZZ A;  1NMA N;  2HTY A;  1NNB A;  4FPL A;  4X47 A;  4QNP A;  1NSB A;  4H53 A;  3TI4 A;  3TIB A;  1F8C A;  1IVG A;  1INX A;  4NCS A;  4KS5 A;  3ALW A;  3CL0 A;  2VWD A;  4K1I A;  4XJU A;  1MS5 A;  4MC7 A;  4HZY A;  4M3M A;  4MJU A;  4XYX A;  3CKZ A;  4B7M A;  2HTV A;  2BAT A;  1DIM A;  1XOE A;  1E8T A;  1NSC A;  4D8S A;  1VCJ A;  2QWJ A;  3GVK A;  1VCU A;  3PJQ A; 
#chains in the Genus database with same CATH topology
 2W5O A;  3DR2 A;  3H6J A;  1X2J A;  4ZY3 A;  7NN9 A;  1Z4W A;  1C9U A;  4IN4 A;  4WEF A;  2F13 A;  5FZJ A;  1WCS A;  4QN3 A;  5FNU A;  3Q6P A;  5FWW A;  1L7H A;  2IAP A;  4XIO A;  2HT5 A;  4FPG A;  1RWL A;  2IAO A;  3E5Z A;  3CL2 A;  5F9T A;  2AH2 A;  2IAQ A;  4B7R A;  2YA7 A;  2XZJ A;  4XHX A;  4MZE A;  2DG0 A;  4GZX A;  2F0Z A;  4QN4 A;  2YA6 A;  4XJ9 A;  2DSO A;  2JKB A;  3G4E A;  1S0J A;  1K32 A;  3II7 A;  3ZGD A;  2VPJ A;  4KS2 A;  4GN7 A;  5JYY A;  3AMS A;  3SLI A;  3V1S A;  1MR5 A;  2F10 A;  1QBI A;  4FZH A;  2W20 A;  3HLH A;  1N1Y A;  4YZ4 A;  5GX3 A;  4KS4 A;  2VW2 A;  1SO7 A;  4UOU A;  4XIK A;  2AEQ A;  3VNH A;  3LI3 A;  4R40 A;  3NSS A;  1NCA N;  3O9K A;  2BER A;  2QWA A;  1KIT A;  4IQK A;  4HZX A;  2YDP A;  5HUM A;  2IAR A;  4AGT A;  2X9M A;  1INF A;  3SRG A;  1IVD A;  1NMB N;  1N1T A;  2GHS A;  3V65 B;  1MS4 A;  1SLI A;  4KS1 A;  4FP3 A;  4MWQ A;  2W8B B;  1USR A;  1N1V A;  2OJH A;  3O9J A;  2QE8 A;  5GX1 A;  4FP2 A;  4GZP A;  4FOV A;  4GZO A;  4IFN X;  4XMA A;  3FVZ A;  3SRE A;  1W0P A;  4WEG A;  4GN9 A;  1L7G A;  2IAS A;  3U0S A;  4FPO B;  4JML A;  2C4L A;  1EUS A;  3K39 A;  1MS8 A;  4HZV A;  4QN6 A;  3KGG A;  1W0O A;  4IFJ A;  5NN9 A;  2POO A;  3Q6T A;  4FVK A;  5D9C A;  2HTR A;  4X6K A;  4D52 A;  4MWY A;  1S0I A;  3SAL A;  2HTU A;  1EUU A;  5GX4 A;  3INB A;  4XMI A;  2F26 A;  1INV A;  3W09 A;  4FOY A;  3BEQ A;  4CPO A;  1N7D A;  1NCB N;  1DIL A;  3S2K A;  3K37 A;  1MZ6 A;  5CGJ A;  4XJ8 A;  1A4G A;  4XJZ A;  1V3D A;  1IVE A;  5D9B A;  2SLI A;  5FNT A;  1MS3 A;  2GVU A;  4M4V A;  4M4U A;  1WCQ A;  5HUN A;  1V04 A;  4MWL A;  1H6L A;  1V3C A;  4HHO A;  4N1B A;  1SNT A;  5B2C A;  4FQ4 A;  5H47 A;  2AGS A;  2IAT A;  2W8B A;  3LI5 A;  3ADE A;  4C1Y B;  4M4N A;  1Z4X A;  3TI5 A;  4GEZ A;  4D52 C;  2F24 A;  3LI4 A;  3JU4 A;  3AMR A;  4L7B A;  1F8B A;  4KS3 A;  1Z4Y A;  4DGR A;  2YDT A;  2AEP A;  4GJT A;  4YW5 A;  3TIC A;  4XHB A;  2F28 A;  4MWW A;  4D4U A;  4DG6 A;  4YZ3 A;  4MX0 A;  4G3N A;  2HT7 A;  3TI6 A;  2F25 A;  1IVF A;  4BBW A;  2W38 A;  4XJW A;  4FOW A;  3SOB B;  3O4P A;  3ALX A;  1V3E A;  1A4Q A;  1NCC N;  4MJV A;  4YY8 A;  4K1K A;  1MWE A;  4GZT A;  1V3B A;  2DG1 A;  1PJX A;  2VSK A;  1N6D A;  2ZB6 A;  3TI3 A;  4CH9 A;  2HU4 A;  2HT8 A;  5EO7 A;  2QWB A;  1Z4V A;  2VK5 A;  2IAX A;  3SOQ A;  2IAV A;  1Z50 A;  5F72 C;  4IYG A;  5EO8 A;  1IUB A;  2QWK A;  3WW9 A;  4J9T A;  3DAS A;  1CVM A;  4XOG A;  4X4A A;  2BZD A;  3UC1 A;  4I00 A;  6NN9 A;  4GDJ A;  4GZQ A;  2IVZ A;  2YA4 A;  4L7C A;  2RKC A;  4FPH A;  2YA8 A;  4ZLR A;  4CPM A;  4K1H A;  1E1A A;  1EUR A;  1V0E A;  3CYE A;  4FPJ A;  3VNG A;  2F12 A;  4GN8 A;  4X49 A;  4XJR A;  4H52 A;  5FNQ A;  1INY A;  4NC5 A;  3A9H A;  3BYC A;  1F8E A;  4YW2 A;  4YW3 A;  2Z32 A;  2HU0 A;  5GX5 A;  5HUK A;  1V0Z A;  1A14 N;  1E8V A;  2V91 A;  4FJ6 A;  4YW1 A;  2XCY A;  4B7J A;  5D9D A;  3S8Z A;  3SAN A;  4WA4 A;  4XE9 A;  3T1E A;  3K36 A;  2XZK A;  4ASC A;  2GVX A;  1BJI A;  4JF7 A;  2C4A A;  2H2N A;  1CRU A;  1N1S A;  2QWD A;  2VAQ A;  4Q1U A;  1MS9 A;  4SLI A;  2H2U A;  1SUU A;  2HTW A;  2DYH A;  1S18 A;  4MWX A;  4MWV A;  2XZI A;  4CSD A;  5HX0 A;  4FPC A;  2IAW A;  1NN2 A;  2QWC A;  3OPZ A;  2VSM A;  3IAX A;  2VW0 A;  3SIL A;  2QWF A;  1INW A;  4B7Q A;  5FNR A;  4XMB A;  4GDI A;  1L7F A;  1W1X A;  4B7N A;  1XOG A;  2W5N A;  3WWA A;  1W21 A;  4XJQ A;  3Q6K A;  2SIM A;  3I1C A;  2FP8 A;  2F11 A;  4A0P A;  3A9G A;  3HRP A;  3K38 A;  2ZWA A;  4YZ2 A;  1W8O A;  2FPC A;  3H73 A;  2ZB5 A;  1USX A;  4FPE A;  5FZN A;  4L7D A;  2VW1 A;  5EX7 A;  4IFL X;  1EUT A;  3GVJ A;  4GB1 A;  1RWI A;  3GVL A;  1MS0 A;  4XIL A;  2QWH A;  2B8H A;  4O5S A;  1CQ1 A;  4FOQ A;  3D12 A;  2F29 A;  2QWI A;  1Z4Z A;  3HLI A;  2F27 A;  4MZA A;  4UF7 A;  3G4H A;  1IVC A;  4HIZ A;  4YZ5 A;  4CPL A;  3A71 A;  3TIA A;  4K3Y A;  4MWJ A;  4WA5 A;  2ISM A;  1NNC A;  1NMC A;  4AHA A;  3K3A A;  2SIL A;  1WP5 A;  2A75 A;  1X2R A;  4GZW A;  3ZGC A;  4MWR A;  3B7E A;  4FPF A;  4NN9 A;  3S94 A;  1NCD N;  2VK7 A;  4C1Y A;  1S1D A;  3NN9 A;  5M1Z A;  3NO0 A;  4HZW A;  1B9V A;  1B9S A;  4XJA A;  3TC9 A;  1MS1 A;  1F8D A;  4YW4 A;  3P5B L;  1ZI0 A;  2YA5 A;  4FPK A;  3TI8 A;  1N6F A;  1IJQ A;  4YZ1 A;  4FPY A;  1NSD A;  5HUG A;  4QN7 A;  5B2D A;  4D52 B;  1V0F A;  1W8N A;  2GVV A;  1E8U A;  2FPB A;  4WA3 A;  3H71 A;  2VK6 A;  2QWE A;  4CHB A;  1ZGK A;  5GTQ A;  4K1J A;  1NNA A;  3D11 A;  2FLU X;  1ING A;  2GVW A;  3B69 A;  2P4O A;  2IAU A;  2QWG A;  4Q6K A;  2ZW9 A;  4GNB A;  4MWU A;  4GNA A;  1IVB A;  4CPN A;  3H72 A;  2FP9 A;  3KYA A;  1SLL A;  4AGI A;  2VVZ A;  4GZS A;  4GNC A;  1NPE A;  2WOZ A;  3A72 A;  1POO A;  1MZ5 A;  1IUC A;  1Q7F A;  1CRZ A;  1OFZ A;  3L6V A;  1INH A;  4CPZ A;  4HHQ A;  4ZGC A;  1W20 A;  4CPY A;  4QN5 A;  2CML A;  1V2I A;  1B9T A;  2BF6 A;  2FHR A;  2HTQ A;  4HZZ A;  1NMA N;  5GX2 A;  2HTY A;  1NNB A;  4FPL A;  4X47 A;  4QNP A;  3WN7 A;  1NSB A;  4H53 A;  5FNS A;  3TI4 A;  3TIB A;  4O5T A;  4HW6 A;  1F8C A;  1IVG A;  1INX A;  3FW0 A;  4NCS A;  4KS5 A;  3ALW A;  3CL0 A;  2VWD A;  4PWZ A;  4K1I A;  4XJU A;  4AH4 A;  1MS5 A;  3WDZ A;  2ZZK A;  4IMB A;  4MC7 A;  4HZY A;  4M3M A;  1N6E A;  4MJU A;  4XYX A;  3CKZ A;  4B7M A;  2HTV A;  2BAT A;  1DIM A;  3V64 C;  1XOE A;  1U6D X;  1E8T A;  1QLG A;  2G8S A;  1C5K A;  1NSC A;  3S8V A;  1VCJ A;  2QWJ A;  2XN4 A;  4D8S A;  2HQS A;  3GVK A;  3SOV A;  1VCU A;  3PJQ A; 
#chains in the Genus database with same CATH homology
 2W5O A;  3H6J A;  7NN9 A;  1Z4W A;  4WEF A;  2F13 A;  1WCS A;  4QN3 A;  1L7H A;  4XIO A;  2HT5 A;  4FPG A;  3CL2 A;  5F9T A;  2AH2 A;  4B7R A;  2YA7 A;  2XZJ A;  4XHX A;  4MZE A;  4GZX A;  2F0Z A;  4QN4 A;  2YA6 A;  4XJ9 A;  2JKB A;  1S0J A;  4KS2 A;  5JYY A;  3SLI A;  1MR5 A;  2F10 A;  4FZH A;  2W20 A;  1N1Y A;  4YZ4 A;  4KS4 A;  2VW2 A;  1SO7 A;  4XIK A;  2AEQ A;  3NSS A;  1NCA N;  3O9K A;  2BER A;  2QWA A;  1KIT A;  4HZX A;  2YDP A;  5HUM A;  2X9M A;  1INF A;  1IVD A;  1NMB N;  1N1T A;  1MS4 A;  1SLI A;  4KS1 A;  4FP3 A;  4MWQ A;  1USR A;  1N1V A;  3O9J A;  4FP2 A;  4GZO A;  4FOV A;  4GZP A;  4XMA A;  1W0P A;  4WEG A;  1L7G A;  4FPO B;  2C4L A;  1EUS A;  3K39 A;  1MS8 A;  4HZV A;  4QN6 A;  1W0O A;  5NN9 A;  4FVK A;  2HTR A;  4X6K A;  4MWY A;  1S0I A;  3SAL A;  2HTU A;  1EUU A;  3INB A;  4XMI A;  2F26 A;  1INV A;  3W09 A;  4FOY A;  3BEQ A;  4CPO A;  1NCB N;  1DIL A;  3K37 A;  1MZ6 A;  4XJ8 A;  1A4G A;  4XJZ A;  1V3D A;  1IVE A;  2SLI A;  1MS3 A;  4M4V A;  4M4U A;  1WCQ A;  5HUN A;  4MWL A;  1V3C A;  1SNT A;  5B2C A;  4FQ4 A;  2AGS A;  4M4N A;  1Z4X A;  3TI5 A;  4GEZ A;  2F24 A;  3JU4 A;  1F8B A;  4KS3 A;  1Z4Y A;  4DGR A;  2YDT A;  2AEP A;  4GJT A;  4YW5 A;  3TIC A;  4XHB A;  2F28 A;  4MWW A;  4YZ3 A;  4MX0 A;  2HT7 A;  3TI6 A;  2F25 A;  1IVF A;  4BBW A;  2W38 A;  4XJW A;  4FOW A;  3ALX A;  1V3E A;  1A4Q A;  1NCC N;  4MJV A;  4K1K A;  1MWE A;  4GZT A;  1V3B A;  2VSK A;  2ZB6 A;  3TI3 A;  2HU4 A;  2HT8 A;  2QWB A;  1Z4V A;  2VK5 A;  1Z50 A;  2QWK A;  4J9T A;  4XOG A;  4X4A A;  2BZD A;  4I00 A;  6NN9 A;  4GDJ A;  4GZQ A;  2YA4 A;  2RKC A;  4FPH A;  2YA8 A;  4CPM A;  4K1H A;  1EUR A;  1V0E A;  3CYE A;  4FPJ A;  2F12 A;  4X49 A;  4XJR A;  4H52 A;  1INY A;  4NC5 A;  1F8E A;  4YW2 A;  4YW3 A;  2HU0 A;  5HUK A;  1V0Z A;  1A14 N;  1E8V A;  4FJ6 A;  4YW1 A;  2XCY A;  4B7J A;  3SAN A;  4WA4 A;  4XE9 A;  3T1E A;  3K36 A;  2XZK A;  1BJI A;  4JF7 A;  2C4A A;  2H2N A;  1N1S A;  2QWD A;  1MS9 A;  4SLI A;  2H2U A;  2HTW A;  1S18 A;  4MWX A;  4MWV A;  2XZI A;  5HX0 A;  4FPC A;  1NN2 A;  2QWC A;  3OPZ A;  2VSM A;  2VW0 A;  3SIL A;  2QWF A;  1INW A;  4B7Q A;  4GDI A;  1L7F A;  1W1X A;  4B7N A;  1XOG A;  2W5N A;  1W21 A;  4XJQ A;  2SIM A;  2F11 A;  3K38 A;  4YZ2 A;  1W8O A;  3H73 A;  2ZB5 A;  1USX A;  4FPE A;  2VW1 A;  1EUT A;  3GVJ A;  4GB1 A;  3GVL A;  1MS0 A;  4XIL A;  2QWH A;  2B8H A;  4FOQ A;  3D12 A;  2F29 A;  2QWI A;  1Z4Z A;  2F27 A;  4MZA A;  4UF7 A;  1IVC A;  4HIZ A;  4YZ5 A;  4CPL A;  3A71 A;  3TIA A;  4K3Y A;  4MWJ A;  4WA5 A;  1NNC A;  1NMC A;  3K3A A;  2SIL A;  2A75 A;  4GZW A;  4MWR A;  3B7E A;  4FPF A;  4NN9 A;  1NCD N;  2VK7 A;  1S1D A;  3NN9 A;  5M1Z A;  4HZW A;  1B9V A;  1B9S A;  4XJA A;  1MS1 A;  1F8D A;  4YW4 A;  2YA5 A;  4FPK A;  3TI8 A;  4YZ1 A;  4FPY A;  1NSD A;  5HUG A;  4QN7 A;  5B2D A;  1V0F A;  1W8N A;  1E8U A;  4WA3 A;  3H71 A;  2VK6 A;  2QWE A;  4K1J A;  1NNA A;  3D11 A;  1ING A;  3B69 A;  2QWG A;  4Q6K A;  4MWU A;  1IVB A;  4CPN A;  3H72 A;  1SLL A;  2VVZ A;  4GZS A;  3A72 A;  1MZ5 A;  1INH A;  4CPZ A;  1W20 A;  4CPY A;  4QN5 A;  2CML A;  1V2I A;  1B9T A;  2BF6 A;  2FHR A;  2HTQ A;  4HZZ A;  1NMA N;  2HTY A;  1NNB A;  4FPL A;  4X47 A;  4QNP A;  1NSB A;  4H53 A;  3TI4 A;  3TIB A;  1F8C A;  1IVG A;  1INX A;  4NCS A;  4KS5 A;  3ALW A;  3CL0 A;  2VWD A;  4K1I A;  4XJU A;  1MS5 A;  4MC7 A;  4HZY A;  4M3M A;  4MJU A;  4XYX A;  3CKZ A;  4B7M A;  2HTV A;  2BAT A;  1DIM A;  1XOE A;  1E8T A;  1NSC A;  4D8S A;  1VCJ A;  2QWJ A;  3GVK A;  1VCU A;  3PJQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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