4X6KA

Crystal structure of the intramolecular trans-sialidase from ruminococcus gnavus in complex with siastatin b
Total Genus 137
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
486
structure length
485
Chain Sequence
ADISNIFYAGDATKSNYFRIPSLLALDSGTVIAAADARYGGTHDAKSKINTAFAKSTDGGKTWGQPTLPLKFDDYVAKNIDWPRDSVGKNVQIQGSASYIDPVLLEDKETHRVFLFADMMPAGIGSSNASVGSGFKEVDGKKYLKLHWKDDAAGTYDYSVRENGTIYNDTTNSATEYSVDGEYNLYKNGNAMLCKQYDYNFEGTKLLETQTDTDVNMNVFYKDADFKVFPTTYLAMKYSDDEGETWSDLQIVSTFKPEESKFLVLGPGVGKQIANGEHAGRLIVPLYSKSSAELGFMYSDDHGNNWTYVEADQNTGGATAEAQIVEMPDGSLKTYLRTGSGYIAQVMSTDGGETWSERVPLTEIATTGYGTQLSVINYSQPVDGKPAILLSAPNATNGRKNGKIWIGLISETGNSGKDKYSVDWKYCYSVDTPQMGYSYSCLTELPDGEIGLLYEKYDSWSRNELHLKNILKYERFNIDELKVQP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Discovery of intramolecular trans-sialidases in human gut microbiota suggests novel mechanisms of mucosal adaptation.
pubmed doi rcsb
molecule tags Hydrolase
source organism Ruminococcus gnavus cc55_001c
molecule keywords Anhydrosialidase
total genus 137
structure length 485
sequence length 486
ec nomenclature
pdb deposition date 2014-12-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.220.10 Mainly Beta Beta Barrel Intramolecular trans-sialidase; domain 3 Intramolecular Trans-sialidase; Domain 3 4x6kA02
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 4x6kA01
2C4AA 5NN9A 2HTUA 1NSCA 2QWCA 4FPGA 1E8TA 1MS8A 4M3MA 4M4UA 2VK5A 3K36A 1INXA 2VW0A 1EUTA 1MS1A 2YA6A 4FOYA 1E8UA 4FPEA 1NCDN 3CL0A 5M1ZA 1INVA 2A75A 4HZZA 1INWA 1MS5A 3D12A 1VCJA 2CMLA 1NCCN 4WA3A 4MZEA 2VVZA 1MS9A 1USXA 2VK7A 4GZWA 2FHRA 5HUKA 4GDJA 4YW1A 1MR5A 3PJQA 1INHA 3B7EA 1IVCA 1Z4XA 2VK6A 4FQ4A 4B7RA 4FPHA 3K37A 2VWDA 4GZTA 4H53A 4FP3A 2F29A 3GVJA 1Z4YA 3K38A 1KITA 1IVEA 3CL2A 3GVLA 3BEQA 3H6JA 4MWYA 2VW1A 3TIBA 1V3BA 2QWHA 1Z4WA 2ZB6A 1XOGA 4KS1A 4GZXA 1IVFA 1N1YA 4MWUA 4MWVA 2QWFA 1Z50A 1W1XA 2BF6A 4XJ9A 2F27A 4FPYA 6NN9A 4CPMA 1NCAN 4GZQA 4MJVA 3NN9A 3H71A 1SO7A 1EUUA 1SLIA 2QWBA 4MZAA 1VCUA 4X6KA 4DGRA 1S0JA 2XZKA 4FPKA 3SLIA 7NN9A 1MS0A 4GDIA 4X4AA 1DIMA 2HTRA 4HIZA 4MX0A 3CKZA 2HT7A 1INFA 2F26A 2QWAA 3TIAA 1L7GA 1S0IA 1E8VA 2HT5A 4MWRA 3SANA 4FOVA 3T1EA 1N1SA 4QN3A 3SILA 4CPNA 4K1HA 2B8HA 5HUGA 1EURA 4XMIA 4B7JA 1INGA 2W5OA 1WCSA 2F0ZA 4FP2A 4YZ5A 2HU4A 1B9TA 4BBWA 4NCSA 1W0OA 2AEPA 2BZDA 2BERA 2F10A 4X49A 3TI5A 2F12A 2RKCA 2XCYA 1NMCA 3B69A 3CYEA 4K1KA 4XHXA 4I00A 2F13A 1MS4A 2HTVA 4FPCA 2YDTA 2HU0A 4HZYA 4CPYA 1A14N 1L7HA 2HT8A 1Z4VA 4FPFA 1MS3A 1V2IA 2VSKA 2BATA 4WA5A 4XJ8A 1B9VA 1WCQA 2XZIA 2YA4A 2AGSA 2X9MA 4NN9A 2YDPA 1IVDA 4CPOA 1V0ZA 4XOGA 4YZ3A 1DILA 3H72A 1NSBA 1Z4ZA 4FPJA 1INYA 1IVGA 2C4LA 1XOEA 2QWDA 4YZ2A 3ALXA 4XILA 1A4GA 2W20A 4XHBA 1W0PA 5JYYA 3A71A 4XE9A 1B9SA 2QWIA 1SNTA 1MZ6A 2F25A 1MWEA 4GZPA 4WEFA 1NN2A 4X47A 5HUMA 2SIMA 4QN5A 4Q6KA 1NSDA 4MWXA 4KS4A 1SLLA 2YA5A 4CPZA 4QN6A 1W8OA 3D11A 4B7NA 2F24A 2JKBA 4YW2A 1F8EA 1USRA 4FZHA 4GZSA 4XJUA 3TICA 4K3YA 4D8SA 4M4VA 3ALWA 3H73A 2YA7A 4B7QA 1N1TA 2HTYA 5B2CA 4WA4A 4J9TA 1NMAN 3OPZA 4GEZA 4XJWA 3TI8A 3W09A 4XMAA 2SLIA 3SALA 1EUSA 4HZXA 4WEGA 2F11A 4NC5A 3INBA 1F8DA 4QN4A 1NNBA 4YW5A 4SLIA 1V3EA 5HX0A 3K39A 2W5NA 4FPOB 1V3CA 4XJZA 4KS2A 4MWLA 1V3DA 4UF7A 4FOQA 2QWJA 4MWWA 2AH2A 2QWEA 3K3AA 3O9JA 4FJ6A 4XJQA 4YW3A 1V0FA 2HTQA 4HZWA 4QNPA 4M4NA 3GVKA 1F8CA 4CPLA 4GZOA 1NNCA 3TI3A 4K1JA 4MWJA 4HZVA 4QN7A 5F9TA 1A4QA 2AEQA 2ZB5A 1NMBN 4MWQA 1IVBA 4FVKA 2VW2A 4MC7A 4XJRA 1F8BA 1W21A 4H52A 3TI6A 1BJIA 1V0EA 4YZ4A 2HTWA 1MZ5A 2XZJA 3NSSA 4K1IA 3TI4A 3O9KA 2F28A 4XYXA 4GB1A 1N1VA 1L7FA 2VSMA 4YZ1A 2SILA 2QWKA 3A72A 4XIKA 1NNAA 4JF7A 4XJAA 5HUNA 5B2DA 4MJUA 4XIOA 1NCBN 2W38A 1W8NA 1W20A 4YW4A 3JU4A 4KS3A 4FOWA 4B7MA 4KS5A 4GJTA 4FPLA 2YA8A 2QWGA
chains in the Genus database with same CATH superfamily
2C4AA 2DYHA 5NN9A 1OFZA 2HTUA 1NSCA 2QWCA 4FPGA 1E8TA 1MS8A 4M3MA 5FNRA 4M4UA 2VK5A 3SOQA 3K36A 1INXA 2P4OA 4GN9A 2VW0A 1SUUA 1EUTA 1MS1A 2YA6A 4FOYA 1E8UA 3VNHA 4FPEA 1NCDN 1S1DA 3CL0A 5M1ZA 1INVA 2A75A 4HZZA 2IAWA 3ADEA 1INWA 3WW9A 1MS5A 1IJQA 2FP9A 3D12A 1VCJA 2CMLA 1NCCN 4WA3A 3S8ZA 4HHQA 5GTQA 4MZEA 2VVZA 1MS9A 5GX4A 3S8VA 1USXA 2VK7A 2QE8A 3Q6KA 3V65B 4GZWA 2FHRA 4Q1UA 5HUKA 4GDJA 4YW1A 1MR5A 3PJQA 4O5SA 2ZZKA 1INHA 3B7EA 1IVCA 1CQ1A 2VK6A 1Z4XA 2V91A 4FQ4A 4B7RA 4N1BA 2IAOA 4FPHA 2OJHA 1IUCA 3DASA 3TC9A 3K37A 2VWDA 4GZTA 4H53A 4FP3A 2W8BB 2F29A 3GVJA 1Z4YA 3K38A 1KITA 1IVEA 3CL2A 4IQKA 3GVLA 3SREA 3BEQA 3LI3A 3H6JA 1N6EA 4MWYA 2VW1A 3E5ZA 3SOVA 3TIBA 4GN8A 1V3BA 3V1SA 2QWHA 1Z4WA 2ZB6A 5FWWA 4AH4A 1XOGA 4C1YB 1N6FA 4KS1A 2FP8A 4GZXA 3NO0A 1IVFA 3Q6TA 1N1YA 4MWUA 4MWVA 3HLIA 2QWFA 1Z50A 3G4HA 1W1XA 2BF6A 3UC1A 3BYCA 4XJ9A 2F27A 1RWLA 4FPYA 2Z32A 6NN9A 4CPMA 2IAXA 1NCAN 1X2JA 4CH9A 4GZQA 2ZW9A 4MJVA 3NN9A 3H71A 3LI5A 1SO7A 1EUUA 4G3NA 3Q6PA 1SLIA 2QWBA 4MZAA 1IUBA 1VCUA 4HHOA 4X6KA 4IFLX 3WN7A 3A9HA 4DGRA 1S0JA 2XZKA 4FPKA 3SLIA 5FNSA 7NN9A 1MS0A 4GDIA 4X4AA 1DIMA 2HTRA 4HIZA 4MX0A 2IAVA 3CKZA 2HT7A 1INFA 4O5TA 2F26A 4JMLA 2IARA 2QWAA 3TIAA 2FPCA 1L7GA 1S0IA 1E8VA 4D52C 1PJXA 2HT5A 5EX7A 4AHAA 1QLGA 4MWRA 2IAQA 3P5BL 3SANA 5FNTA 2WOZA 4FOVA 3T1EA 1X2RA 3HLHA 2IAUA 1N1SA 4QN3A 3SILA 1CRUA 4CPNA 4K1HA 2B8HA 5HUGA 1EURA 4XMIA 1E1AA 2GVUA 4B7JA 1INGA 2W5OA 1WCSA 2F0ZA 4FP2A 1N7DA 4ZGCA 2IVZA 4YZ5A 2HU4A 1B9TA 2GVVA 4BBWA 4R40A 1U6DX 4NCSA 1W0OA 2AEPA 2BZDA 2BERA 2F10A 4X49A 3TI5A 2F12A 2RKCA 2GHSA 2G8SA 2XCYA 4IN4A 2DSOA 1NMCA 3B69A 3ZGDA 3CYEA 4K1KA 4XHXA 1CRZA 4I00A 2F13A 1MS4A 2XN4A 2HTVA 4FPCA 1ZI0A 1NPEA 2YDTA 2HU0A 4HZYA 4CPYA 1A14N 1L7HA 2HT8A 3V64C 3O4PA 1Z4VA 4PWZA 4D52B 4FPFA 1MS3A 1V2IA 2VSKA 2BATA 4WA5A 4XJ8A 1B9VA 5FNQA 1WCQA 2XZIA 2YA4A 1ZGKA 4IFNX 2AGSA 2X9MA 4NN9A 2YDPA 5H47A 1IVDA 4D4UA 1C5KA 4CPOA 2W8BA 1V0ZA 4XOGA 4YZ3A 1DILA 3H72A 2POOA 3FW0A 1NSBA 1Z4ZA 3KGGA 4FPJA 1INYA 1IVGA 2C4LA 1XOEA 2QWDA 4YZ2A 3ALXA 3DR2A 3FVZA 4C1YA 4XILA 1A4GA 2ZWAA 2W20A 4XHBA 5GX5A 1W0PA 5F72C 5GX3A 5JYYA 3A71A 4XE9A 1B9SA 2H2UA 1S18A 1SNTA 2QWIA 3AMSA 1MZ6A 2F25A 1MWEA 4XMBA 4GZPA 4WEFA 1NN2A 4X47A 5HUMA 2SIMA 4QN5A 3WDZA 4Q6KA 1NSDA 4MWXA 2H2NA 4KS4A 1SLLA 2YA5A 4CPZA 1POOA 2GVXA 4ASCA 4QN6A 1W8OA 3D11A 4B7NA 3II7A 2DG0A 3AMRA 2F24A 4ZY3A 2JKBA 4YW2A 4GNBA 1F8EA 1USRA 4FZHA 4GZSA 4XJUA 3S94A 3TICA 4K3YA 3ZGCA 4D8SA 1N6DA 5GX2A 4M4VA 5EO8A 4GN7A 2GVWA 3ALWA 2VAQA 5D9BA 4GNAA 3H73A 2YA7A 4B7QA 1N1TA 2HTYA 3KYAA 5B2CA 4WA4A 3A9GA 4CSDA 4J9TA 3HRPA 1NMAN 3OPZA 4GEZA 4XJWA 1H6LA 5FNUA 3TI8A 2FPBA 3W09A 4XMAA 2VPJA 2SLIA 3SALA 1EUSA 1K32A 2IAPA 4HZXA 4WEGA 5D9CA 2F11A 4NC5A 3INBA 1F8DA 4QN4A 1NNBA 3SOBB 4YW5A 4SLIA 1V3EA 1C9UA 5HX0A 3K39A 2W5NA 4FPOB 4L7BA 1V3CA 5D9DA 4XJZA 4KS2A 4MWLA 1V3DA 4UF7A 4FOQA 2QWJA 4MWWA 2AH2A 2IASA 2QWEA 2HQSA 3K3AA 3O9JA 3IAXA 4FJ6A 4XJQA 4YW3A 1V0FA 2HTQA 1CVMA 1V04A 4HZWA 4QNPA 4M4NA 5FZNA 3GVKA 1F8CA 4IFJA 4CPLA 4D52A 4GZOA 4ZLRA 3U0SA 1NNCA 3TI3A 4K1JA 4MWJA 2FLUX 1RWIA 4HZVA 4IMBA 4QN7A 5F9TA 1A4QA 2AEQA 2ZB5A 1NMBN 4MWQA 1IVBA 2IATA 2ISMA 4FVKA 2VW2A 4MC7A 4AGTA 2DG1A 1F8BA 4XJRA 1W21A 4H52A 4AGIA 3TI6A 3S2KA 5GX1A 1BJIA 1V0EA 5EO7A 4YZ4A 3LI4A 2HTWA 4CHBA 1MZ5A 2XZJA 4IYGA 3NSSA 4A0PA 5CGJA 4K1IA 3TI4A 4YY8A 3O9KA 2F28A 4XYXA 4GB1A 1N1VA 1L7FA 2VSMA 3WWAA 3L6VA 4YZ1A 4L7DA 3VNGA 2SILA 2QWKA 3A72A 5FZJA 4XIKA 1NNAA 4JF7A 4XJAA 5HUNA 3G4EA 4UOUA 5B2DA 3I1CA 4MJUA 4XIOA 1NCBN 2W38A 1W8NA 1W20A 4GNCA 4YW4A 1Q7FA 3SRGA 3JU4A 4HW6A 4KS3A 4FOWA 4DG6A 4B7MA 4L7CA 4KS5A 4GJTA 4FPLA 2YA8A 2QWGA 1WP5A 1QBIA
chains in the Genus database with same CATH topology
2C4AA 5NN9A 2HTUA 1NSCA 2QWCA 4FPGA 1E8TA 1MS8A 4M3MA 4M4UA 2VK5A 3K36A 1INXA 2VW0A 1EUTA 1MS1A 2YA6A 4FOYA 1E8UA 4FPEA 1NCDN 1S1DA 3CL0A 5M1ZA 1INVA 2A75A 4HZZA 1INWA 1MS5A 3D12A 1VCJA 2CMLA 1NCCN 4WA3A 4MZEA 2VVZA 1MS9A 1USXA 2VK7A 4GZWA 2FHRA 5HUKA 4GDJA 4YW1A 1MR5A 3PJQA 1INHA 3B7EA 1IVCA 2VK6A 1Z4XA 4FQ4A 4B7RA 4FPHA 3K37A 2VWDA 4GZTA 4H53A 4FP3A 2F29A 3GVJA 1Z4YA 3K38A 1KITA 1IVEA 3CL2A 3GVLA 3BEQA 3H6JA 4MWYA 2VW1A 3TIBA 1V3BA 2QWHA 1Z4WA 2ZB6A 1XOGA 4KS1A 4GZXA 1IVFA 1N1YA 4MWUA 4MWVA 2QWFA 1Z50A 1W1XA 2BF6A 4XJ9A 2F27A 4FPYA 6NN9A 4CPMA 1NCAN 4GZQA 4MJVA 3NN9A 3H71A 1SO7A 1EUUA 1SLIA 2QWBA 4MZAA 1VCUA 4X6KA 4DGRA 1S0JA 2XZKA 4FPKA 3SLIA 7NN9A 1MS0A 4GDIA 4X4AA 1DIMA 2HTRA 4HIZA 4MX0A 3CKZA 2HT7A 1INFA 2F26A 2QWAA 3TIAA 1L7GA 1S0IA 1E8VA 2HT5A 4MWRA 3SANA 4FOVA 3T1EA 1N1SA 4QN3A 3SILA 4CPNA 4K1HA 2B8HA 5HUGA 1EURA 4XMIA 4B7JA 1INGA 2W5OA 1WCSA 2F0ZA 4FP2A 4YZ5A 2HU4A 1B9TA 4BBWA 4NCSA 1W0OA 2AEPA 2BZDA 2BERA 2F10A 4X49A 3TI5A 2F12A 2RKCA 2XCYA 1NMCA 3B69A 3CYEA 4K1KA 4XHXA 4I00A 2F13A 1MS4A 2HTVA 4FPCA 2YDTA 2HU0A 4HZYA 4CPYA 1A14N 1L7HA 2HT8A 1Z4VA 4FPFA 1MS3A 1V2IA 2VSKA 2BATA 4WA5A 4XJ8A 1B9VA 1WCQA 2XZIA 2YA4A 2AGSA 2X9MA 4NN9A 2YDPA 1IVDA 4CPOA 1V0ZA 4XOGA 4YZ3A 1DILA 3H72A 1NSBA 1Z4ZA 4FPJA 1INYA 1IVGA 2C4LA 1XOEA 2QWDA 4YZ2A 3ALXA 4XILA 1A4GA 2W20A 4XHBA 1W0PA 5JYYA 3A71A 4XE9A 1B9SA 2H2UA 1S18A 1SNTA 2QWIA 1MZ6A 2F25A 1MWEA 4GZPA 4WEFA 1NN2A 4X47A 5HUMA 2SIMA 4QN5A 4Q6KA 1NSDA 4MWXA 2H2NA 4KS4A 1SLLA 2YA5A 4CPZA 4QN6A 1W8OA 3D11A 4B7NA 2F24A 2JKBA 4YW2A 1F8EA 1USRA 4FZHA 4GZSA 4XJUA 3TICA 4K3YA 4D8SA 4M4VA 3ALWA 3H73A 2YA7A 4B7QA 1N1TA 2HTYA 5B2CA 4WA4A 4J9TA 1NMAN 3OPZA 4GEZA 4XJWA 3TI8A 3W09A 4XMAA 2SLIA 3SALA 1EUSA 4HZXA 4WEGA 2F11A 4NC5A 3INBA 1F8DA 4QN4A 1NNBA 4YW5A 4SLIA 1V3EA 5HX0A 3K39A 2W5NA 4FPOB 1V3CA 4XJZA 4KS2A 4MWLA 1V3DA 4UF7A 4FOQA 2QWJA 4MWWA 2AH2A 2QWEA 3K3AA 3O9JA 4FJ6A 4XJQA 4YW3A 1V0FA 2HTQA 4HZWA 4QNPA 4M4NA 3GVKA 1F8CA 4CPLA 4GZOA 1NNCA 3TI3A 4K1JA 4MWJA 4HZVA 4QN7A 5F9TA 1A4QA 2AEQA 2ZB5A 1NMBN 4MWQA 1IVBA 4FVKA 2VW2A 4MC7A 4XJRA 1F8BA 1W21A 4H52A 3TI6A 1BJIA 1V0EA 4YZ4A 2HTWA 1MZ5A 2XZJA 3NSSA 4K1IA 3TI4A 3O9KA 2F28A 4XYXA 4GB1A 1N1VA 1L7FA 2VSMA 4YZ1A 2SILA 2QWKA 3A72A 4XIKA 1NNAA 4JF7A 4XJAA 5HUNA 5B2DA 4MJUA 4XIOA 1NCBN 2W38A 1W8NA 1W20A 4YW4A 3JU4A 4KS3A 4FOWA 4B7MA 4KS5A 4GJTA 4FPLA 2YA8A 2QWGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C4A A;  5NN9 A;  2HTU A;  1NSC A;  2QWC A;  4FPG A;  1E8T A;  1MS8 A;  4M3M A;  4M4U A;  2VK5 A;  3K36 A;  1INX A;  2VW0 A;  1EUT A;  1MS1 A;  2YA6 A;  4FOY A;  1E8U A;  4FPE A;  1NCD N;  3CL0 A;  5M1Z A;  1INV A;  2A75 A;  4HZZ A;  1INW A;  1MS5 A;  3D12 A;  1VCJ A;  2CML A;  1NCC N;  4WA3 A;  4MZE A;  2VVZ A;  1MS9 A;  1USX A;  2VK7 A;  4GZW A;  2FHR A;  5HUK A;  4GDJ A;  4YW1 A;  1MR5 A;  3PJQ A;  1INH A;  3B7E A;  1IVC A;  1Z4X A;  2VK6 A;  4FQ4 A;  4B7R A;  4FPH A;  3K37 A;  2VWD A;  4GZT A;  4H53 A;  4FP3 A;  2F29 A;  3GVJ A;  1Z4Y A;  3K38 A;  1KIT A;  1IVE A;  3CL2 A;  3GVL A;  3BEQ A;  3H6J A;  4MWY A;  2VW1 A;  3TIB A;  1V3B A;  2QWH A;  1Z4W A;  2ZB6 A;  1XOG A;  4KS1 A;  4GZX A;  1IVF A;  1N1Y A;  4MWU A;  4MWV A;  2QWF A;  1Z50 A;  1W1X A;  2BF6 A;  4XJ9 A;  2F27 A;  4FPY A;  6NN9 A;  4CPM A;  1NCA N;  4GZQ A;  4MJV A;  3NN9 A;  3H71 A;  1SO7 A;  1EUU A;  1SLI A;  2QWB A;  4MZA A;  1VCU A;  4X6K A;  4DGR A;  1S0J A;  2XZK A;  4FPK A;  3SLI A;  7NN9 A;  1MS0 A;  4GDI A;  4X4A A;  1DIM A;  2HTR A;  4HIZ A;  4MX0 A;  3CKZ A;  2HT7 A;  1INF A;  2F26 A;  2QWA A;  3TIA A;  1L7G A;  1S0I A;  1E8V A;  2HT5 A;  4MWR A;  3SAN A;  4FOV A;  3T1E A;  1N1S A;  4QN3 A;  3SIL A;  4CPN A;  4K1H A;  2B8H A;  5HUG A;  1EUR A;  4XMI A;  4B7J A;  1ING A;  2W5O A;  1WCS A;  2F0Z A;  4FP2 A;  4YZ5 A;  2HU4 A;  1B9T A;  4BBW A;  4NCS A;  1W0O A;  2AEP A;  2BZD A;  2BER A;  2F10 A;  4X49 A;  3TI5 A;  2F12 A;  2RKC A;  2XCY A;  1NMC A;  3B69 A;  3CYE A;  4K1K A;  4XHX A;  4I00 A;  2F13 A;  1MS4 A;  2HTV A;  4FPC A;  2YDT A;  2HU0 A;  4HZY A;  4CPY A;  1A14 N;  1L7H A;  2HT8 A;  1Z4V A;  4FPF A;  1MS3 A;  1V2I A;  2VSK A;  2BAT A;  4WA5 A;  4XJ8 A;  1B9V A;  1WCQ A;  2XZI A;  2YA4 A;  2AGS A;  2X9M A;  4NN9 A;  2YDP A;  1IVD A;  4CPO A;  1V0Z A;  4XOG A;  4YZ3 A;  1DIL A;  3H72 A;  1NSB A;  1Z4Z A;  4FPJ A;  1INY A;  1IVG A;  2C4L A;  1XOE A;  2QWD A;  4YZ2 A;  3ALX A;  4XIL A;  1A4G A;  2W20 A;  4XHB A;  1W0P A;  5JYY A;  3A71 A;  4XE9 A;  1B9S A;  2QWI A;  1SNT A;  1MZ6 A;  2F25 A;  1MWE A;  4GZP A;  4WEF A;  1NN2 A;  4X47 A;  5HUM A;  2SIM A;  4QN5 A;  4Q6K A;  1NSD A;  4MWX A;  4KS4 A;  1SLL A;  2YA5 A;  4CPZ A;  4QN6 A;  1W8O A;  3D11 A;  4B7N A;  2F24 A;  2JKB A;  4YW2 A;  1F8E A;  1USR A;  4FZH A;  4GZS A;  4XJU A;  3TIC A;  4K3Y A;  4D8S A;  4M4V A;  3ALW A;  3H73 A;  2YA7 A;  4B7Q A;  1N1T A;  2HTY A;  5B2C A;  4WA4 A;  4J9T A;  1NMA N;  3OPZ A;  4GEZ A;  4XJW A;  3TI8 A;  3W09 A;  4XMA A;  2SLI A;  3SAL A;  1EUS A;  4HZX A;  4WEG A;  2F11 A;  4NC5 A;  3INB A;  1F8D A;  4QN4 A;  1NNB A;  4YW5 A;  4SLI A;  1V3E A;  5HX0 A;  3K39 A;  2W5N A;  4FPO B;  1V3C A;  4XJZ A;  4KS2 A;  4MWL A;  1V3D A;  4UF7 A;  4FOQ A;  2QWJ A;  4MWW A;  2AH2 A;  2QWE A;  3K3A A;  3O9J A;  4FJ6 A;  4XJQ A;  4YW3 A;  1V0F A;  2HTQ A;  4HZW A;  4QNP A;  4M4N A;  3GVK A;  1F8C A;  4CPL A;  4GZO A;  1NNC A;  3TI3 A;  4K1J A;  4MWJ A;  4HZV A;  4QN7 A;  5F9T A;  1A4Q A;  2AEQ A;  2ZB5 A;  1NMB N;  4MWQ A;  1IVB A;  4FVK A;  2VW2 A;  4MC7 A;  4XJR A;  1F8B A;  1W21 A;  4H52 A;  3TI6 A;  1BJI A;  1V0E A;  4YZ4 A;  2HTW A;  1MZ5 A;  2XZJ A;  3NSS A;  4K1I A;  3TI4 A;  3O9K A;  2F28 A;  4XYX A;  4GB1 A;  1N1V A;  1L7F A;  2VSM A;  4YZ1 A;  2SIL A;  2QWK A;  3A72 A;  4XIK A;  1NNA A;  4JF7 A;  4XJA A;  5HUN A;  5B2D A;  4MJU A;  4XIO A;  1NCB N;  2W38 A;  1W8N A;  1W20 A;  4YW4 A;  3JU4 A;  4KS3 A;  4FOW A;  4B7M A;  4KS5 A;  4GJT A;  4FPL A;  2YA8 A;  2QWG A; 
#chains in the Genus database with same CATH topology
 2C4A A;  2DYH A;  5NN9 A;  1OFZ A;  2HTU A;  1NSC A;  2QWC A;  4FPG A;  1E8T A;  1MS8 A;  4M3M A;  5FNR A;  4M4U A;  2VK5 A;  3SOQ A;  3K36 A;  1INX A;  2P4O A;  4GN9 A;  2VW0 A;  1SUU A;  1EUT A;  1MS1 A;  2YA6 A;  4FOY A;  1E8U A;  3VNH A;  4FPE A;  1NCD N;  1S1D A;  3CL0 A;  5M1Z A;  1INV A;  2A75 A;  4HZZ A;  2IAW A;  3ADE A;  1INW A;  3WW9 A;  1MS5 A;  1IJQ A;  2FP9 A;  3D12 A;  1VCJ A;  2CML A;  1NCC N;  4WA3 A;  3S8Z A;  4HHQ A;  5GTQ A;  4MZE A;  2VVZ A;  1MS9 A;  5GX4 A;  3S8V A;  1USX A;  2VK7 A;  2QE8 A;  3Q6K A;  3V65 B;  4GZW A;  2FHR A;  4Q1U A;  5HUK A;  4GDJ A;  4YW1 A;  1MR5 A;  3PJQ A;  4O5S A;  2ZZK A;  1INH A;  3B7E A;  1IVC A;  1CQ1 A;  2VK6 A;  1Z4X A;  2V91 A;  4FQ4 A;  4B7R A;  4N1B A;  2IAO A;  4FPH A;  2OJH A;  1IUC A;  3DAS A;  3TC9 A;  3K37 A;  2VWD A;  4GZT A;  4H53 A;  4FP3 A;  2W8B B;  2F29 A;  3GVJ A;  1Z4Y A;  3K38 A;  1KIT A;  1IVE A;  3CL2 A;  4IQK A;  3GVL A;  3SRE A;  3BEQ A;  3LI3 A;  3H6J A;  1N6E A;  4MWY A;  2VW1 A;  3E5Z A;  3SOV A;  3TIB A;  4GN8 A;  1V3B A;  3V1S A;  2QWH A;  1Z4W A;  2ZB6 A;  5FWW A;  4AH4 A;  1XOG A;  4C1Y B;  1N6F A;  4KS1 A;  2FP8 A;  4GZX A;  3NO0 A;  1IVF A;  3Q6T A;  1N1Y A;  4MWU A;  4MWV A;  3HLI A;  2QWF A;  1Z50 A;  3G4H A;  1W1X A;  2BF6 A;  3UC1 A;  3BYC A;  4XJ9 A;  2F27 A;  1RWL A;  4FPY A;  2Z32 A;  6NN9 A;  4CPM A;  2IAX A;  1NCA N;  1X2J A;  4CH9 A;  4GZQ A;  2ZW9 A;  4MJV A;  3NN9 A;  3H71 A;  3LI5 A;  1SO7 A;  1EUU A;  4G3N A;  3Q6P A;  1SLI A;  2QWB A;  4MZA A;  1IUB A;  1VCU A;  4HHO A;  4X6K A;  4IFL X;  3WN7 A;  3A9H A;  4DGR A;  1S0J A;  2XZK A;  4FPK A;  3SLI A;  5FNS A;  7NN9 A;  1MS0 A;  4GDI A;  4X4A A;  1DIM A;  2HTR A;  4HIZ A;  4MX0 A;  2IAV A;  3CKZ A;  2HT7 A;  1INF A;  4O5T A;  2F26 A;  4JML A;  2IAR A;  2QWA A;  3TIA A;  2FPC A;  1L7G A;  1S0I A;  1E8V A;  4D52 C;  1PJX A;  2HT5 A;  5EX7 A;  4AHA A;  1QLG A;  4MWR A;  2IAQ A;  3P5B L;  3SAN A;  5FNT A;  2WOZ A;  4FOV A;  3T1E A;  1X2R A;  3HLH A;  2IAU A;  1N1S A;  4QN3 A;  3SIL A;  1CRU A;  4CPN A;  4K1H A;  2B8H A;  5HUG A;  1EUR A;  4XMI A;  1E1A A;  2GVU A;  4B7J A;  1ING A;  2W5O A;  1WCS A;  2F0Z A;  4FP2 A;  1N7D A;  4ZGC A;  2IVZ A;  4YZ5 A;  2HU4 A;  1B9T A;  2GVV A;  4BBW A;  4R40 A;  1U6D X;  4NCS A;  1W0O A;  2AEP A;  2BZD A;  2BER A;  2F10 A;  4X49 A;  3TI5 A;  2F12 A;  2RKC A;  2GHS A;  2G8S A;  2XCY A;  4IN4 A;  2DSO A;  1NMC A;  3B69 A;  3ZGD A;  3CYE A;  4K1K A;  4XHX A;  1CRZ A;  4I00 A;  2F13 A;  1MS4 A;  2XN4 A;  2HTV A;  4FPC A;  1ZI0 A;  1NPE A;  2YDT A;  2HU0 A;  4HZY A;  4CPY A;  1A14 N;  1L7H A;  2HT8 A;  3V64 C;  3O4P A;  1Z4V A;  4PWZ A;  4D52 B;  4FPF A;  1MS3 A;  1V2I A;  2VSK A;  2BAT A;  4WA5 A;  4XJ8 A;  1B9V A;  5FNQ A;  1WCQ A;  2XZI A;  2YA4 A;  1ZGK A;  4IFN X;  2AGS A;  2X9M A;  4NN9 A;  2YDP A;  5H47 A;  1IVD A;  4D4U A;  1C5K A;  4CPO A;  2W8B A;  1V0Z A;  4XOG A;  4YZ3 A;  1DIL A;  3H72 A;  2POO A;  3FW0 A;  1NSB A;  1Z4Z A;  3KGG A;  4FPJ A;  1INY A;  1IVG A;  2C4L A;  1XOE A;  2QWD A;  4YZ2 A;  3ALX A;  3DR2 A;  3FVZ A;  4C1Y A;  4XIL A;  1A4G A;  2ZWA A;  2W20 A;  4XHB A;  5GX5 A;  1W0P A;  5F72 C;  5GX3 A;  5JYY A;  3A71 A;  4XE9 A;  1B9S A;  2H2U A;  1S18 A;  1SNT A;  2QWI A;  3AMS A;  1MZ6 A;  2F25 A;  1MWE A;  4XMB A;  4GZP A;  4WEF A;  1NN2 A;  4X47 A;  5HUM A;  2SIM A;  4QN5 A;  3WDZ A;  4Q6K A;  1NSD A;  4MWX A;  2H2N A;  4KS4 A;  1SLL A;  2YA5 A;  4CPZ A;  1POO A;  2GVX A;  4ASC A;  4QN6 A;  1W8O A;  3D11 A;  4B7N A;  3II7 A;  2DG0 A;  3AMR A;  2F24 A;  4ZY3 A;  2JKB A;  4YW2 A;  4GNB A;  1F8E A;  1USR A;  4FZH A;  4GZS A;  4XJU A;  3S94 A;  3TIC A;  4K3Y A;  3ZGC A;  4D8S A;  1N6D A;  5GX2 A;  4M4V A;  5EO8 A;  4GN7 A;  2GVW A;  3ALW A;  2VAQ A;  5D9B A;  4GNA A;  3H73 A;  2YA7 A;  4B7Q A;  1N1T A;  2HTY A;  3KYA A;  5B2C A;  4WA4 A;  3A9G A;  4CSD A;  4J9T A;  3HRP A;  1NMA N;  3OPZ A;  4GEZ A;  4XJW A;  1H6L A;  5FNU A;  3TI8 A;  2FPB A;  3W09 A;  4XMA A;  2VPJ A;  2SLI A;  3SAL A;  1EUS A;  1K32 A;  2IAP A;  4HZX A;  4WEG A;  5D9C A;  2F11 A;  4NC5 A;  3INB A;  1F8D A;  4QN4 A;  1NNB A;  3SOB B;  4YW5 A;  4SLI A;  1V3E A;  1C9U A;  5HX0 A;  3K39 A;  2W5N A;  4FPO B;  4L7B A;  1V3C A;  5D9D A;  4XJZ A;  4KS2 A;  4MWL A;  1V3D A;  4UF7 A;  4FOQ A;  2QWJ A;  4MWW A;  2AH2 A;  2IAS A;  2QWE A;  2HQS A;  3K3A A;  3O9J A;  3IAX A;  4FJ6 A;  4XJQ A;  4YW3 A;  1V0F A;  2HTQ A;  1CVM A;  1V04 A;  4HZW A;  4QNP A;  4M4N A;  5FZN A;  3GVK A;  1F8C A;  4IFJ A;  4CPL A;  4D52 A;  4GZO A;  4ZLR A;  3U0S A;  1NNC A;  3TI3 A;  4K1J A;  4MWJ A;  2FLU X;  1RWI A;  4HZV A;  4IMB A;  4QN7 A;  5F9T A;  1A4Q A;  2AEQ A;  2ZB5 A;  1NMB N;  4MWQ A;  1IVB A;  2IAT A;  2ISM A;  4FVK A;  2VW2 A;  4MC7 A;  4AGT A;  2DG1 A;  1F8B A;  4XJR A;  1W21 A;  4H52 A;  4AGI A;  3TI6 A;  3S2K A;  5GX1 A;  1BJI A;  1V0E A;  5EO7 A;  4YZ4 A;  3LI4 A;  2HTW A;  4CHB A;  1MZ5 A;  2XZJ A;  4IYG A;  3NSS A;  4A0P A;  5CGJ A;  4K1I A;  3TI4 A;  4YY8 A;  3O9K A;  2F28 A;  4XYX A;  4GB1 A;  1N1V A;  1L7F A;  2VSM A;  3WWA A;  3L6V A;  4YZ1 A;  4L7D A;  3VNG A;  2SIL A;  2QWK A;  3A72 A;  5FZJ A;  4XIK A;  1NNA A;  4JF7 A;  4XJA A;  5HUN A;  3G4E A;  4UOU A;  5B2D A;  3I1C A;  4MJU A;  4XIO A;  1NCB N;  2W38 A;  1W8N A;  1W20 A;  4GNC A;  4YW4 A;  1Q7F A;  3SRG A;  3JU4 A;  4HW6 A;  4KS3 A;  4FOW A;  4DG6 A;  4B7M A;  4L7C A;  4KS5 A;  4GJT A;  4FPL A;  2YA8 A;  2QWG A;  1WP5 A;  1QBI A; 
#chains in the Genus database with same CATH homology
 2C4A A;  5NN9 A;  2HTU A;  1NSC A;  2QWC A;  4FPG A;  1E8T A;  1MS8 A;  4M3M A;  4M4U A;  2VK5 A;  3K36 A;  1INX A;  2VW0 A;  1EUT A;  1MS1 A;  2YA6 A;  4FOY A;  1E8U A;  4FPE A;  1NCD N;  1S1D A;  3CL0 A;  5M1Z A;  1INV A;  2A75 A;  4HZZ A;  1INW A;  1MS5 A;  3D12 A;  1VCJ A;  2CML A;  1NCC N;  4WA3 A;  4MZE A;  2VVZ A;  1MS9 A;  1USX A;  2VK7 A;  4GZW A;  2FHR A;  5HUK A;  4GDJ A;  4YW1 A;  1MR5 A;  3PJQ A;  1INH A;  3B7E A;  1IVC A;  2VK6 A;  1Z4X A;  4FQ4 A;  4B7R A;  4FPH A;  3K37 A;  2VWD A;  4GZT A;  4H53 A;  4FP3 A;  2F29 A;  3GVJ A;  1Z4Y A;  3K38 A;  1KIT A;  1IVE A;  3CL2 A;  3GVL A;  3BEQ A;  3H6J A;  4MWY A;  2VW1 A;  3TIB A;  1V3B A;  2QWH A;  1Z4W A;  2ZB6 A;  1XOG A;  4KS1 A;  4GZX A;  1IVF A;  1N1Y A;  4MWU A;  4MWV A;  2QWF A;  1Z50 A;  1W1X A;  2BF6 A;  4XJ9 A;  2F27 A;  4FPY A;  6NN9 A;  4CPM A;  1NCA N;  4GZQ A;  4MJV A;  3NN9 A;  3H71 A;  1SO7 A;  1EUU A;  1SLI A;  2QWB A;  4MZA A;  1VCU A;  4X6K A;  4DGR A;  1S0J A;  2XZK A;  4FPK A;  3SLI A;  7NN9 A;  1MS0 A;  4GDI A;  4X4A A;  1DIM A;  2HTR A;  4HIZ A;  4MX0 A;  3CKZ A;  2HT7 A;  1INF A;  2F26 A;  2QWA A;  3TIA A;  1L7G A;  1S0I A;  1E8V A;  2HT5 A;  4MWR A;  3SAN A;  4FOV A;  3T1E A;  1N1S A;  4QN3 A;  3SIL A;  4CPN A;  4K1H A;  2B8H A;  5HUG A;  1EUR A;  4XMI A;  4B7J A;  1ING A;  2W5O A;  1WCS A;  2F0Z A;  4FP2 A;  4YZ5 A;  2HU4 A;  1B9T A;  4BBW A;  4NCS A;  1W0O A;  2AEP A;  2BZD A;  2BER A;  2F10 A;  4X49 A;  3TI5 A;  2F12 A;  2RKC A;  2XCY A;  1NMC A;  3B69 A;  3CYE A;  4K1K A;  4XHX A;  4I00 A;  2F13 A;  1MS4 A;  2HTV A;  4FPC A;  2YDT A;  2HU0 A;  4HZY A;  4CPY A;  1A14 N;  1L7H A;  2HT8 A;  1Z4V A;  4FPF A;  1MS3 A;  1V2I A;  2VSK A;  2BAT A;  4WA5 A;  4XJ8 A;  1B9V A;  1WCQ A;  2XZI A;  2YA4 A;  2AGS A;  2X9M A;  4NN9 A;  2YDP A;  1IVD A;  4CPO A;  1V0Z A;  4XOG A;  4YZ3 A;  1DIL A;  3H72 A;  1NSB A;  1Z4Z A;  4FPJ A;  1INY A;  1IVG A;  2C4L A;  1XOE A;  2QWD A;  4YZ2 A;  3ALX A;  4XIL A;  1A4G A;  2W20 A;  4XHB A;  1W0P A;  5JYY A;  3A71 A;  4XE9 A;  1B9S A;  2H2U A;  1S18 A;  1SNT A;  2QWI A;  1MZ6 A;  2F25 A;  1MWE A;  4GZP A;  4WEF A;  1NN2 A;  4X47 A;  5HUM A;  2SIM A;  4QN5 A;  4Q6K A;  1NSD A;  4MWX A;  2H2N A;  4KS4 A;  1SLL A;  2YA5 A;  4CPZ A;  4QN6 A;  1W8O A;  3D11 A;  4B7N A;  2F24 A;  2JKB A;  4YW2 A;  1F8E A;  1USR A;  4FZH A;  4GZS A;  4XJU A;  3TIC A;  4K3Y A;  4D8S A;  4M4V A;  3ALW A;  3H73 A;  2YA7 A;  4B7Q A;  1N1T A;  2HTY A;  5B2C A;  4WA4 A;  4J9T A;  1NMA N;  3OPZ A;  4GEZ A;  4XJW A;  3TI8 A;  3W09 A;  4XMA A;  2SLI A;  3SAL A;  1EUS A;  4HZX A;  4WEG A;  2F11 A;  4NC5 A;  3INB A;  1F8D A;  4QN4 A;  1NNB A;  4YW5 A;  4SLI A;  1V3E A;  5HX0 A;  3K39 A;  2W5N A;  4FPO B;  1V3C A;  4XJZ A;  4KS2 A;  4MWL A;  1V3D A;  4UF7 A;  4FOQ A;  2QWJ A;  4MWW A;  2AH2 A;  2QWE A;  3K3A A;  3O9J A;  4FJ6 A;  4XJQ A;  4YW3 A;  1V0F A;  2HTQ A;  4HZW A;  4QNP A;  4M4N A;  3GVK A;  1F8C A;  4CPL A;  4GZO A;  1NNC A;  3TI3 A;  4K1J A;  4MWJ A;  4HZV A;  4QN7 A;  5F9T A;  1A4Q A;  2AEQ A;  2ZB5 A;  1NMB N;  4MWQ A;  1IVB A;  4FVK A;  2VW2 A;  4MC7 A;  4XJR A;  1F8B A;  1W21 A;  4H52 A;  3TI6 A;  1BJI A;  1V0E A;  4YZ4 A;  2HTW A;  1MZ5 A;  2XZJ A;  3NSS A;  4K1I A;  3TI4 A;  3O9K A;  2F28 A;  4XYX A;  4GB1 A;  1N1V A;  1L7F A;  2VSM A;  4YZ1 A;  2SIL A;  2QWK A;  3A72 A;  4XIK A;  1NNA A;  4JF7 A;  4XJA A;  5HUN A;  5B2D A;  4MJU A;  4XIO A;  1NCB N;  2W38 A;  1W8N A;  1W20 A;  4YW4 A;  3JU4 A;  4KS3 A;  4FOW A;  4B7M A;  4KS5 A;  4GJT A;  4FPL A;  2YA8 A;  2QWG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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