2DYHA

Crystal structure of the keap1 protein in complexed with the n-terminal region of the nrf2 transcription factor
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
296
structure length
296
Chain Sequence
VGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response
pubmed doi rcsb
molecule keywords Kelch-like ECH-associated protein 1
molecule tags Transcription
source organism Mus musculus
total genus 66
structure length 296
sequence length 296
ec nomenclature
pdb deposition date 2006-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 2dyhA00
4CHBA 5FNRA 3VNGA 4IN4A 4ZY3A 1ZGKA 4L7CA 2DYHA 5FZJA 1X2RA 5FZNA 3VNHA 3WDZA 2Z32A 1U6DX 2WOZA 4L7DA 4ZGCA 2ZZKA 4IFJA 3ADEA 5FNUA 4IQKA 5FNSA 4IFNX 2VPJA 5CGJA 5FNTA 1X2JA 2XN4A 4L7BA 4IFLX 2ZWAA 5FNQA 3ZGDA 3ZGCA 2ZW9A 4XMBA 4YY8A 3II7A 4ASCA 2FLUX 5F72C 4CH9A 3WN7A 4N1BA
chains in the Genus database with same CATH superfamily
2IAVA 2SIMA 4XIKA 1W0PA 3WW9A 2QWJA 3KYAA 4KS3A 2W20A 5FZJA 1CVMA 5D9DA 3Q6TA 2HT7A 4MWUA 1L7FA 5FNUA 3SOQA 5GX2A 2G8SA 2IAPA 4AGTA 4XOGA 2HU4A 3ALXA 2YA5A 4HZXA 2VK6A 1E8VA 2CMLA 3SRGA 3NN9A 2FP9A 4O5TA 4GDIA 5GTQA 4FPKA 1ZI0A 3TC9A 2BZDA 4FPEA 4CSDA 1U6DX 4YW5A 1C9UA 3V1SA 5FNTA 1IUBA 3OPZA 3E5ZA 1MS4A 1MZ6A 2ZWAA 4K1JA 3S8VA 1NSCA 1INFA 1MS1A 4K1IA 2AEQA 2AEPA 1IVDA 4YZ4A 3G4EA 4MWLA 4MWJA 4MWVA 1IVCA 1E8UA 1SUUA 3S2KA 3TI4A 2ZB6A 5F9TA 3WDZA 1A14N 2YA8A 3SALA 2WOZA 3O4PA 1EUTA 2FHRA 2HTRA 2VW1A 4I00A 4GJTA 1L7GA 2QE8A 1RWLA 4XJAA 4UF7A 1MS9A 3TI6A 4MZEA 2GVXA 4Q6KA 1Z50A 3WN7A 1W0OA 2QWKA 4QN4A 2IAQA 4JF7A 1W20A 2B8HA 4CPYA 4GZTA 4O5SA 4XIOA 2DYHA 3S94A 3JU4A 1X2RA 1S1DA 2VSKA 4GEZA 1WCSA 4YZ2A 1V3DA 1SLLA 2HTUA 1V3BA 2F10A 3A9GA 1Z4XA 3ALWA 4M4VA 4K1HA 4GN9A 3TICA 2GVVA 2ZW9A 4FPYA 4YZ3A 4KS1A 3K39A 4FP2A 4B7RA 2SILA 2HQSA 5FNRA 4GNCA 4MWRA 4J9TA 2HTVA 1INGA 3VNHA 1F8DA 1S0IA 2FPCA 4B7MA 3GVLA 4QN6A 1H6LA 5HX0A 3ADEA 1MS3A 1NMAN 2JKBA 4A0PA 2IASA 3HLHA 3H71A 3H72A 4QN3A 1F8EA 1N6DA 2XCYA 3AMSA 2VAQA 4YW1A 5B2CA 3BEQA 4QN7A 4FJ6A 5GX4A 3HRPA 2VWDA 1OFZA 4FP3A 4ZY3A 1Z4ZA 1K32A 4HZWA 2FP8A 1E8TA 1MS0A 3A9HA 1INWA 4C1YA 4QNPA 3NSSA 4L7DA 1B9TA 2F11A 4DG6A 2DSOA 4BBWA 1Q7FA 3H6JA 3SLIA 3TIBA 1V2IA 1V0FA 1E1AA 4L7BA 2W5NA 1N1SA 1VCUA 5NN9A 4H52A 3WWAA 2QWDA 4XMBA 3NO0A 3TIAA 4FPHA 1CRUA 1WP5A 3VNGA 4HZZA 2F12A 2QWCA 2C4LA 4M4NA 5HUGA 1S0JA 4XJWA 1IVFA 4MJVA 1XOGA 2ZZKA 4X6KA 4MX0A 3IAXA 3B69A 4GZWA 4IFNX 2VPJA 2AGSA 4B7NA 2F29A 2QWIA 4D52C 3A72A 3UC1A 5FNQA 2W38A 5H47A 5JYYA 1INYA 4D8SA 4KS4A 4WA5A 4GN7A 4GNAA 4D4UA 4KS2A 2F26A 3SANA 4CHBA 3S8ZA 1CQ1A 4XJ8A 4IN4A 4FPFA 2DG0A 3TI5A 4C1YB 2BATA 5FZNA 2GVWA 4FPOB 1NNBA 4JMLA 4SLIA 4DGRA 4XHBA 2W5OA 1EUUA 3A71A 3U0SA 2AH2A 1MS5A 1INHA 2VK7A 1XOEA 4X4AA 1SO7A 4XJUA 1V0ZA 2A75A 2BF6A 4AH4A 1ZGKA 5D9CA 4HHQA 3CL0A 4NCSA 1IUCA 2P4OA 2XZIA 2F0ZA 1N6EA 1W21A 1V0EA 4XJZA 1INVA 3CKZA 2IAOA 3B7EA 3H73A 1QLGA 2F28A 3CYEA 3PJQA 1Z4VA 1RWIA 1EUSA 2IATA 3II7A 4GZXA 3DR2A 5HUMA 1V3EA 2HTQA 2X9MA 1NNAA 4D52A 4CPNA 5EO8A 4GNBA 3HLIA 3L6VA 1NCBN 2FPBA 2HTWA 1CRZA 4M4UA 1N1TA 2XZKA 3T1EA 3K3AA 5EO7A 1EURA 3V64C 2V91A 4IQKA 4YZ1A 5CGJA 3AMRA 2XN4A 1W8OA 2QWHA 1NPEA 4QN5A 4FQ4A 3SILA 2HT5A 2XZJA 3I1CA 5F72C 1NSBA 4N1BA 4WEGA 2GVUA 2HT8A 4XJRA 2VVZA 1Z4WA 3K38A 4FOQA 2YDPA 1F8BA 4HZYA 2YA6A 4R40A 5EX7A 1IVBA 4HW6A 1VCJA 4AHAA 1NCCN 2RKCA 4XJ9A 4K1KA 3DASA 2QWAA 3TI8A 2F25A 4YY8A 1NSDA 4AGIA 1N1VA 4D52B 3GVJA 4FZHA 2H2UA 3Q6PA 4FPCA 4GZPA 2BERA 2IAWA 4IMBA 5GX3A 2VK5A 2IVZA 3TI3A 4HZVA 1N6FA 3KGGA 4XYXA 2OJHA 5GX5A 4GB1A 3D11A 1A4GA 4CPOA 1MR5A 3LI4A 4FOVA 4X49A 1KITA 4GDJA 2QWFA 5D9BA 3K36A 4MJUA 4Q1UA 4MWXA 4ZLRA 3INBA 2F27A 2YDTA 3FVZA 4WEFA 3SREA 2YA7A 4XILA 1NCDN 5GX1A 3V65B 4NC5A 2ZB5A 1DIMA 4FOWA 2POOA 4WA4A 3FW0A 4MWQA 4PWZA 4FOYA 4NN9A 1NN2A 1NMBN 1W8NA 4H53A 3ZGCA 2IAUA 4CPZA 2QWBA 4FPGA 4MWYA 1L7HA 5B2DA 1USRA 4ASCA 1Z4YA 4CH9A 1NCAN 3P5BL 2W8BA 1W1XA 3SOBB 5FWWA 1V3CA 4MZAA 2F13A 4L7CA 2HU0A 2IAXA 3BYCA 1IVGA 4YW2A 1S18A 2Z32A 6NN9A 5HUNA 1F8CA 4IFJA 1WCQA 7NN9A 4WA3A 5FNSA 1B9SA 4IYGA 4XMAA 4K3YA 1B9VA 4CPLA 1NMCA 3G4HA 4M3MA 3SOVA 4B7QA 2F24A 4B7JA 3D12A 4GZOA 2SLIA 2QWEA 4MWWA 4GN8A 1MS8A 3Q6KA 2QWGA 4FVKA 1QBIA 1N1YA 1SLIA 3O9KA 3O9JA 2GHSA 1NNCA 1USXA 4GZSA 4X47A 2VW0A 4MC7A 2H2NA 3CL2A 1PJXA 1A4QA 1POOA 4XMIA 4IFLX 2ISMA 4XE9A 1IVEA 4YW3A 2W8BB 1V04A 1DILA 5M1ZA 2DG1A 3LI5A 1N7DA 4CPMA 4GZQA 4G3NA 3K37A 4YZ5A 3LI3A 4HIZA 1BJIA 4FPJA 1INXA 1MZ5A 3W09A 4XHXA 2C4AA 2VSMA 1IJQA 5HUKA 4ZGCA 2YA4A 4YW4A 1SNTA 2IARA 4XJQA 2VW2A 4FPLA 1X2JA 3ZGDA 4KS5A 3GVKA 4UOUA 1MWEA 2HTYA 2FLUX 1C5KA 4HHOA
chains in the Genus database with same CATH topology
4CHBA 5FNRA 3VNGA 4IN4A 4ZY3A 1ZGKA 4L7CA 2DYHA 5FZJA 1X2RA 5FZNA 3VNHA 3WDZA 2Z32A 1U6DX 2WOZA 4L7DA 4ZGCA 2ZZKA 4IFJA 3ADEA 5FNUA 4IQKA 5FNSA 4IFNX 2VPJA 5CGJA 5FNTA 1X2JA 2XN4A 4L7BA 4IFLX 2ZWAA 5FNQA 3ZGDA 3ZGCA 2ZW9A 4XMBA 4YY8A 3II7A 4ASCA 2FLUX 5F72C 4CH9A 3WN7A 4N1BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CHB A;  5FNR A;  3VNG A;  4IN4 A;  4ZY3 A;  1ZGK A;  4L7C A;  2DYH A;  5FZJ A;  1X2R A;  5FZN A;  3VNH A;  3WDZ A;  2Z32 A;  1U6D X;  2WOZ A;  4L7D A;  4ZGC A;  2ZZK A;  4IFJ A;  3ADE A;  5FNU A;  4IQK A;  5FNS A;  4IFN X;  2VPJ A;  5CGJ A;  5FNT A;  1X2J A;  2XN4 A;  4L7B A;  4IFL X;  2ZWA A;  5FNQ A;  3ZGD A;  3ZGC A;  2ZW9 A;  4XMB A;  4YY8 A;  3II7 A;  4ASC A;  2FLU X;  5F72 C;  4CH9 A;  3WN7 A;  4N1B A; 
#chains in the Genus database with same CATH topology
 2IAV A;  2SIM A;  4XIK A;  1W0P A;  3WW9 A;  2QWJ A;  3KYA A;  4KS3 A;  2W20 A;  5FZJ A;  1CVM A;  5D9D A;  3Q6T A;  2HT7 A;  4MWU A;  1L7F A;  5FNU A;  3SOQ A;  5GX2 A;  2G8S A;  2IAP A;  4AGT A;  4XOG A;  2HU4 A;  3ALX A;  2YA5 A;  4HZX A;  2VK6 A;  1E8V A;  2CML A;  3SRG A;  3NN9 A;  2FP9 A;  4O5T A;  4GDI A;  5GTQ A;  4FPK A;  1ZI0 A;  3TC9 A;  2BZD A;  4FPE A;  4CSD A;  1U6D X;  4YW5 A;  1C9U A;  3V1S A;  5FNT A;  1IUB A;  3OPZ A;  3E5Z A;  1MS4 A;  1MZ6 A;  2ZWA A;  4K1J A;  3S8V A;  1NSC A;  1INF A;  1MS1 A;  4K1I A;  2AEQ A;  2AEP A;  1IVD A;  4YZ4 A;  3G4E A;  4MWL A;  4MWJ A;  4MWV A;  1IVC A;  1E8U A;  1SUU A;  3S2K A;  3TI4 A;  2ZB6 A;  5F9T A;  3WDZ A;  1A14 N;  2YA8 A;  3SAL A;  2WOZ A;  3O4P A;  1EUT A;  2FHR A;  2HTR A;  2VW1 A;  4I00 A;  4GJT A;  1L7G A;  2QE8 A;  1RWL A;  4XJA A;  4UF7 A;  1MS9 A;  3TI6 A;  4MZE A;  2GVX A;  4Q6K A;  1Z50 A;  3WN7 A;  1W0O A;  2QWK A;  4QN4 A;  2IAQ A;  4JF7 A;  1W20 A;  2B8H A;  4CPY A;  4GZT A;  4O5S A;  4XIO A;  2DYH A;  3S94 A;  3JU4 A;  1X2R A;  1S1D A;  2VSK A;  4GEZ A;  1WCS A;  4YZ2 A;  1V3D A;  1SLL A;  2HTU A;  1V3B A;  2F10 A;  3A9G A;  1Z4X A;  3ALW A;  4M4V A;  4K1H A;  4GN9 A;  3TIC A;  2GVV A;  2ZW9 A;  4FPY A;  4YZ3 A;  4KS1 A;  3K39 A;  4FP2 A;  4B7R A;  2SIL A;  2HQS A;  5FNR A;  4GNC A;  4MWR A;  4J9T A;  2HTV A;  1ING A;  3VNH A;  1F8D A;  1S0I A;  2FPC A;  4B7M A;  3GVL A;  4QN6 A;  1H6L A;  5HX0 A;  3ADE A;  1MS3 A;  1NMA N;  2JKB A;  4A0P A;  2IAS A;  3HLH A;  3H71 A;  3H72 A;  4QN3 A;  1F8E A;  1N6D A;  2XCY A;  3AMS A;  2VAQ A;  4YW1 A;  5B2C A;  3BEQ A;  4QN7 A;  4FJ6 A;  5GX4 A;  3HRP A;  2VWD A;  1OFZ A;  4FP3 A;  4ZY3 A;  1Z4Z A;  1K32 A;  4HZW A;  2FP8 A;  1E8T A;  1MS0 A;  3A9H A;  1INW A;  4C1Y A;  4QNP A;  3NSS A;  4L7D A;  1B9T A;  2F11 A;  4DG6 A;  2DSO A;  4BBW A;  1Q7F A;  3H6J A;  3SLI A;  3TIB A;  1V2I A;  1V0F A;  1E1A A;  4L7B A;  2W5N A;  1N1S A;  1VCU A;  5NN9 A;  4H52 A;  3WWA A;  2QWD A;  4XMB A;  3NO0 A;  3TIA A;  4FPH A;  1CRU A;  1WP5 A;  3VNG A;  4HZZ A;  2F12 A;  2QWC A;  2C4L A;  4M4N A;  5HUG A;  1S0J A;  4XJW A;  1IVF A;  4MJV A;  1XOG A;  2ZZK A;  4X6K A;  4MX0 A;  3IAX A;  3B69 A;  4GZW A;  4IFN X;  2VPJ A;  2AGS A;  4B7N A;  2F29 A;  2QWI A;  4D52 C;  3A72 A;  3UC1 A;  5FNQ A;  2W38 A;  5H47 A;  5JYY A;  1INY A;  4D8S A;  4KS4 A;  4WA5 A;  4GN7 A;  4GNA A;  4D4U A;  4KS2 A;  2F26 A;  3SAN A;  4CHB A;  3S8Z A;  1CQ1 A;  4XJ8 A;  4IN4 A;  4FPF A;  2DG0 A;  3TI5 A;  4C1Y B;  2BAT A;  5FZN A;  2GVW A;  4FPO B;  1NNB A;  4JML A;  4SLI A;  4DGR A;  4XHB A;  2W5O A;  1EUU A;  3A71 A;  3U0S A;  2AH2 A;  1MS5 A;  1INH A;  2VK7 A;  1XOE A;  4X4A A;  1SO7 A;  4XJU A;  1V0Z A;  2A75 A;  2BF6 A;  4AH4 A;  1ZGK A;  5D9C A;  4HHQ A;  3CL0 A;  4NCS A;  1IUC A;  2P4O A;  2XZI A;  2F0Z A;  1N6E A;  1W21 A;  1V0E A;  4XJZ A;  1INV A;  3CKZ A;  2IAO A;  3B7E A;  3H73 A;  1QLG A;  2F28 A;  3CYE A;  3PJQ A;  1Z4V A;  1RWI A;  1EUS A;  2IAT A;  3II7 A;  4GZX A;  3DR2 A;  5HUM A;  1V3E A;  2HTQ A;  2X9M A;  1NNA A;  4D52 A;  4CPN A;  5EO8 A;  4GNB A;  3HLI A;  3L6V A;  1NCB N;  2FPB A;  2HTW A;  1CRZ A;  4M4U A;  1N1T A;  2XZK A;  3T1E A;  3K3A A;  5EO7 A;  1EUR A;  3V64 C;  2V91 A;  4IQK A;  4YZ1 A;  5CGJ A;  3AMR A;  2XN4 A;  1W8O A;  2QWH A;  1NPE A;  4QN5 A;  4FQ4 A;  3SIL A;  2HT5 A;  2XZJ A;  3I1C A;  5F72 C;  1NSB A;  4N1B A;  4WEG A;  2GVU A;  2HT8 A;  4XJR A;  2VVZ A;  1Z4W A;  3K38 A;  4FOQ A;  2YDP A;  1F8B A;  4HZY A;  2YA6 A;  4R40 A;  5EX7 A;  1IVB A;  4HW6 A;  1VCJ A;  4AHA A;  1NCC N;  2RKC A;  4XJ9 A;  4K1K A;  3DAS A;  2QWA A;  3TI8 A;  2F25 A;  4YY8 A;  1NSD A;  4AGI A;  1N1V A;  4D52 B;  3GVJ A;  4FZH A;  2H2U A;  3Q6P A;  4FPC A;  4GZP A;  2BER A;  2IAW A;  4IMB A;  5GX3 A;  2VK5 A;  2IVZ A;  3TI3 A;  4HZV A;  1N6F A;  3KGG A;  4XYX A;  2OJH A;  5GX5 A;  4GB1 A;  3D11 A;  1A4G A;  4CPO A;  1MR5 A;  3LI4 A;  4FOV A;  4X49 A;  1KIT A;  4GDJ A;  2QWF A;  5D9B A;  3K36 A;  4MJU A;  4Q1U A;  4MWX A;  4ZLR A;  3INB A;  2F27 A;  2YDT A;  3FVZ A;  4WEF A;  3SRE A;  2YA7 A;  4XIL A;  1NCD N;  5GX1 A;  3V65 B;  4NC5 A;  2ZB5 A;  1DIM A;  4FOW A;  2POO A;  4WA4 A;  3FW0 A;  4MWQ A;  4PWZ A;  4FOY A;  4NN9 A;  1NN2 A;  1NMB N;  1W8N A;  4H53 A;  3ZGC A;  2IAU A;  4CPZ A;  2QWB A;  4FPG A;  4MWY A;  1L7H A;  5B2D A;  1USR A;  4ASC A;  1Z4Y A;  4CH9 A;  1NCA N;  3P5B L;  2W8B A;  1W1X A;  3SOB B;  5FWW A;  1V3C A;  4MZA A;  2F13 A;  4L7C A;  2HU0 A;  2IAX A;  3BYC A;  1IVG A;  4YW2 A;  1S18 A;  2Z32 A;  6NN9 A;  5HUN A;  1F8C A;  4IFJ A;  1WCQ A;  7NN9 A;  4WA3 A;  5FNS A;  1B9S A;  4IYG A;  4XMA A;  4K3Y A;  1B9V A;  4CPL A;  1NMC A;  3G4H A;  4M3M A;  3SOV A;  4B7Q A;  2F24 A;  4B7J A;  3D12 A;  4GZO A;  2SLI A;  2QWE A;  4MWW A;  4GN8 A;  1MS8 A;  3Q6K A;  2QWG A;  4FVK A;  1QBI A;  1N1Y A;  1SLI A;  3O9K A;  3O9J A;  2GHS A;  1NNC A;  1USX A;  4GZS A;  4X47 A;  2VW0 A;  4MC7 A;  2H2N A;  3CL2 A;  1PJX A;  1A4Q A;  1POO A;  4XMI A;  4IFL X;  2ISM A;  4XE9 A;  1IVE A;  4YW3 A;  2W8B B;  1V04 A;  1DIL A;  5M1Z A;  2DG1 A;  3LI5 A;  1N7D A;  4CPM A;  4GZQ A;  4G3N A;  3K37 A;  4YZ5 A;  3LI3 A;  4HIZ A;  1BJI A;  4FPJ A;  1INX A;  1MZ5 A;  3W09 A;  4XHX A;  2C4A A;  2VSM A;  1IJQ A;  5HUK A;  4ZGC A;  2YA4 A;  4YW4 A;  1SNT A;  2IAR A;  4XJQ A;  2VW2 A;  4FPL A;  1X2J A;  3ZGD A;  4KS5 A;  3GVK A;  4UOU A;  1MWE A;  2HTY A;  2FLU X;  1C5K A;  4HHO A; 
#chains in the Genus database with same CATH homology
 4CHB A;  5FNR A;  3VNG A;  4IN4 A;  4ZY3 A;  1ZGK A;  4L7C A;  2DYH A;  5FZJ A;  1X2R A;  5FZN A;  3VNH A;  3WDZ A;  2Z32 A;  1U6D X;  2WOZ A;  4L7D A;  4ZGC A;  2ZZK A;  4IFJ A;  3ADE A;  5FNU A;  4IQK A;  5FNS A;  4IFN X;  2VPJ A;  5CGJ A;  5FNT A;  1X2J A;  2XN4 A;  4L7B A;  4IFL X;  2ZWA A;  5FNQ A;  3ZGD A;  3ZGC A;  2ZW9 A;  4XMB A;  4YY8 A;  3II7 A;  4ASC A;  2FLU X;  5F72 C;  4CH9 A;  3WN7 A;  4N1B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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