2WOZA

The novel beta-propeller of the btb-kelch protein krp1 provides the binding site for lasp-1 that is necessary for pseudopodia extension
Total Genus 54
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
318
structure length
307
Chain Sequence
PGYLNDIPRHGMFVKDLILLVNDTAAVAYDPMENECYLTALAEQIPRNHSSIVTQQNQVYVVGGLYVPLQSYFFQLDNVSSEWVGLPPLPSARCLFGLGEVDDKIYVVAGKDLQTEASLDSVLCYDPVAAKWSEVKNLPIKVYGHNVISHNGMIYCLGGKTDDKKCTNRVFIYNPKKGDWKDLAPMKTPRSMFGVAIHKGKIVIAGGVTEDGLSASVEAFDLKTNKWEVMTEFPQERSSISLVSLAGSLYAIGGFAMIQEFAPTEVNDIWKYEDDKKEWAGMLKEIRYASGASCLATRLNLFKLSKL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Novel beta-propeller of the BTB-Kelch protein Krp1 provides a binding site for Lasp-1 that is necessary for pseudopodial extension.
pubmed doi rcsb
molecule keywords KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 10
molecule tags Protein binding
source organism Rattus norvegicus
total genus 54
structure length 307
sequence length 318
ec nomenclature
pdb deposition date 2009-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 2wozA00
4L7DA 3VNGA 2ZWAA 4IQKA 5FNSA 4CHBA 1U6DX 5FZJA 4L7CA 4L7BA 4IFJA 2DYHA 4ASCA 2ZZKA 1X2RA 3ZGCA 1ZGKA 2WOZA 3II7A 2XN4A 5FZNA 4CH9A 5FNUA 4YY8A 5FNRA 4IN4A 4N1BA 3WDZA 3ADEA 2VPJA 2ZW9A 4XMBA 5FNTA 5F72C 3ZGDA 4IFLX 4IFNX 1X2JA 2Z32A 4ZGCA 3WN7A 5CGJA 4ZY3A 5FNQA 2FLUX 3VNHA
chains in the Genus database with same CATH superfamily
4JMLA 2ZWAA 1Z4VA 2IASA 4GZSA 1U6DX 4WEGA 1INFA 1WP5A 2QWGA 4GZPA 2B8HA 1NMCA 4HIZA 4PWZA 4FP2A 4MWWA 4MJUA 1V3DA 3WWAA 5JYYA 1W1XA 4GNAA 4YW3A 4XMBA 4D52A 1MS8A 4IFLX 5B2CA 4X47A 4AGIA 4XJWA 2XZKA 5EO8A 4FVKA 4GZTA 4QN4A 2IVZA 3Q6TA 2QE8A 4QN3A 1NCDN 3TI3A 4X49A 3Q6KA 2DG1A 3ALXA 4XHBA 5HUKA 3WDZA 4IN4A 4H52A 3NSSA 4M4NA 2F0ZA 2VW0A 4M4VA 2GVWA 2FPBA 4GJTA 2Z32A 4FJ6A 3K36A 4FPFA 1QBIA 2VSKA 3ALWA 3HLIA 1Z50A 2F10A 2P4OA 4IQKA 4AH4A 2RKCA 4MWXA 3LI5A 3FVZA 3AMRA 1USRA 4FPOB 3V65B 4FOWA 1W20A 3UC1A 3D11A 3DASA 2W5NA 1N1TA 2W8BB 2WOZA 4XHXA 4FPHA 5FNUA 5GX1A 3ADEA 2VPJA 4K1HA 3ZGDA 4HZXA 1DIMA 2F26A 4HHOA 1W0PA 1N1SA 3BYCA 4XJZA 3S8ZA 1Z4WA 2YA5A 4M3MA 2QWDA 2VK5A 5D9BA 1NNAA 4B7RA 2IAXA 1L7HA 4GZWA 4FPGA 3SLIA 3TIAA 4KS5A 3NO0A 1W21A 2QWFA 4MZEA 3S94A 2GVVA 4KS1A 7NN9A 1ZI0A 1F8CA 2YA7A 5FNRA 2F25A 4FPJA 2AEQA 3H71A 1S0JA 1B9VA 4GZQA 1C5KA 1E1AA 2F12A 2VK6A 3IAXA 4GN8A 2IAVA 4K1IA 2W20A 1E8UA 2JKBA 5FNSA 4MC7A 5FZJA 5F9TA 4L7CA 3HLHA 2QWKA 5NN9A 4YW4A 2HT5A 2POOA 3I1CA 4XJ9A 3S2KA 1ZGKA 3FW0A 2F13A 4CPYA 1IVCA 5HUGA 2VW2A 4N1BA 3WW9A 2ISMA 4XJ8A 3H6JA 2ZW9A 2BATA 1A4QA 3TICA 1V3EA 1V3BA 1SO7A 2HT8A 2YA8A 3SOQA 3WN7A 3A71A 3KYAA 4D8SA 3TI5A 3O9JA 4AHAA 4Q6KA 4MWLA 1F8EA 1INGA 4FPLA 3T1EA 4K3YA 4B7NA 3E5ZA 3SRGA 4FPYA 2GVUA 3HRPA 1W0OA 2IAOA 3SILA 4KS2A 4C1YA 1IVGA 4MWUA 3SOBB 2QWHA 1OFZA 1K32A 5FZNA 3KGGA 4GN9A 4QN7A 2ZB5A 4YZ5A 3B7EA 1MS1A 5HUMA 4HZYA 1N7DA 3TI6A 1NN2A 4FOYA 2F11A 4WA4A 2XZJA 3A72A 4MWYA 4O5SA 3VNGA 4KS4A 5GTQA 1POOA 1USXA 3DR2A 3SREA 1EUTA 4ZLRA 4XILA 4G3NA 1IVFA 4HW6A 2FP8A 2SLIA 2ZZKA 1X2RA 4FPEA 4GEZA 4I00A 4M4UA 3A9GA 1N6DA 1SLIA 3H73A 4YY8A 4UOUA 3B69A 1Q7FA 3LI4A 1V0EA 3U0SA 1IJQA 2IARA 2VSMA 1A4GA 2VK7A 4MJVA 4DG6A 3TC9A 4HZVA 4B7MA 1N1VA 1N6FA 1B9SA 4CHBA 4FPCA 1E8TA 1SNTA 5D9CA 1F8BA 3JU4A 1MS5A 2YA4A 3SALA 2QWJA 1VCUA 3S8VA 5B2DA 1CRUA 4KS3A 3AMSA 3INBA 1INXA 1EURA 2BF6A 4GNCA 4WA3A 5EO7A 3CL0A 2F29A 2DSOA 2H2UA 1QLGA 2BZDA 2HTQA 4B7JA 4WEFA 4H53A 1WCSA 5EX7A 1NNCA 4XYXA 4B7QA 3CL2A 3CKZA 1IVBA 2HQSA 1NCCN 4ASCA 3G4EA 2HU0A 5D9DA 4K1KA 2W8BA 1NMBN 1NNBA 4MWRA 2OJHA 3Q6PA 4AGTA 4CPMA 1BJIA 2QWBA 4XOGA 1F8DA 2HTVA 3K38A 2QWEA 4XJUA 4GZXA 4YZ4A 1S18A 5HUNA 4XJQA 4MX0A 2VWDA 1WCQA 3CYEA 3VNHA 1IUBA 3K39A 1INHA 4FQ4A 4UF7A 2FP9A 2V91A 3V64C 1V0ZA 4GN7A 4IFJA 1IVDA 3L6VA 1Z4XA 3O4PA 4XJAA 1DILA 4QN6A 1NSDA 5GX3A 4YZ2A 5M1ZA 1V0FA 1IUCA 4ZGCA 5GX2A 3BEQA 1E8VA 4GNBA 3D12A 4L7DA 1V2IA 2VW1A 4J9TA 4IYGA 4HZZA 4X6KA 4C1YB 1XOGA 1RWLA 4YW1A 2F24A 2QWAA 1KITA 1S1DA 4XE9A 1EUUA 2ZB6A 4XIOA 1H6LA 1B9TA 4XJRA 2A75A 1XOEA 2VAQA 4R40A 4HHQA 4D52B 1NCAN 2SIMA 2XZIA 1X2JA 2X9MA 4QNPA 5FNQA 2FLUX 4JF7A 2C4AA 4YZ3A 1VCJA 2HTRA 3GVJA 4CPOA 3II7A 1NSCA 1RWIA 4O5TA 1MS4A 2FHRA 4CPLA 4YW2A 4FP3A 2IATA 5F72C 3SANA 2DG0A 2IAWA 4QN5A 2VVZA 4CPNA 1SUUA 4SLIA 1IVEA 4FOVA 1Z4ZA 2CMLA 2AGSA 4L7BA 5H47A 2DYHA 3TI4A 1V3CA 1L7FA 4GB1A 3ZGCA 1CVMA 1SLLA 3TI8A 4FOQA 1MZ6A 1A14N 1MS9A 3A9HA 4CPZA 2HTWA 1CRZA 2XCYA 1NCBN 2G8SA 4NC5A 3OPZA 4X4AA 4XMAA 2HT7A 1MS3A 1INYA 4FZHA 4GDIA 4CSDA 4WA5A 1N1YA 5GX4A 3O9KA 4XIKA 2GVXA 4NCSA 2IAPA 1MS0A 3TIBA 4D4UA 4BBWA 3P5BL 4MZAA 6NN9A 1MZ5A 5CGJA 1S0IA 2F28A 3K3AA 2QWIA 2GHSA 3GVKA 3PJQA 1NMAN 4FPKA 4YZ1A 4YW5A 4GDJA 1PJXA 3V1SA 4Q1UA 2W38A 1NPEA 2SILA 4XMIA 4MWJA 2YA6A 1EUSA 2XN4A 4CH9A 5HX0A 3SOVA 4DGRA 4A0PA 2C4LA 4IFNX 3G4HA 1CQ1A 3W09A 4MWQA 3GVLA 2HU4A 3H72A 1V04A 4MWVA 2FPCA 2AH2A 1C9UA 2HTYA 4NN9A 4IMBA 1W8NA 1MWEA 1N6EA 2BERA 2IAQA 4K1JA 2F27A 4GZOA 2HTUA 2W5OA 4HZWA 4D52C 1INWA 1Z4YA 3K37A 1L7GA 2YDPA 1NSBA 5FNTA 3NN9A 1W8OA 5FWWA 2AEPA 2H2NA 2IAUA 1INVA 2YDTA 3LI3A 2QWCA 4ZY3A 5GX5A 1MR5A
chains in the Genus database with same CATH topology
4L7DA 3VNGA 2ZWAA 4IQKA 5FNSA 4CHBA 1U6DX 5FZJA 4L7CA 4L7BA 4IFJA 2DYHA 4ASCA 2ZZKA 1X2RA 3ZGCA 1ZGKA 2WOZA 3II7A 2XN4A 5FZNA 4CH9A 5FNUA 4YY8A 5FNRA 4IN4A 4N1BA 3WDZA 3ADEA 2VPJA 2ZW9A 4XMBA 5FNTA 5F72C 3ZGDA 4IFLX 4IFNX 1X2JA 2Z32A 4ZGCA 3WN7A 5CGJA 4ZY3A 5FNQA 2FLUX 3VNHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L7D A;  3VNG A;  2ZWA A;  4IQK A;  5FNS A;  4CHB A;  1U6D X;  5FZJ A;  4L7C A;  4L7B A;  4IFJ A;  2DYH A;  4ASC A;  2ZZK A;  1X2R A;  3ZGC A;  1ZGK A;  2WOZ A;  3II7 A;  2XN4 A;  5FZN A;  4CH9 A;  5FNU A;  4YY8 A;  5FNR A;  4IN4 A;  4N1B A;  3WDZ A;  3ADE A;  2VPJ A;  2ZW9 A;  4XMB A;  5FNT A;  5F72 C;  3ZGD A;  4IFL X;  4IFN X;  1X2J A;  2Z32 A;  4ZGC A;  3WN7 A;  5CGJ A;  4ZY3 A;  5FNQ A;  2FLU X;  3VNH A; 
#chains in the Genus database with same CATH topology
 4JML A;  2ZWA A;  1Z4V A;  2IAS A;  4GZS A;  1U6D X;  4WEG A;  1INF A;  1WP5 A;  2QWG A;  4GZP A;  2B8H A;  1NMC A;  4HIZ A;  4PWZ A;  4FP2 A;  4MWW A;  4MJU A;  1V3D A;  3WWA A;  5JYY A;  1W1X A;  4GNA A;  4YW3 A;  4XMB A;  4D52 A;  1MS8 A;  4IFL X;  5B2C A;  4X47 A;  4AGI A;  4XJW A;  2XZK A;  5EO8 A;  4FVK A;  4GZT A;  4QN4 A;  2IVZ A;  3Q6T A;  2QE8 A;  4QN3 A;  1NCD N;  3TI3 A;  4X49 A;  3Q6K A;  2DG1 A;  3ALX A;  4XHB A;  5HUK A;  3WDZ A;  4IN4 A;  4H52 A;  3NSS A;  4M4N A;  2F0Z A;  2VW0 A;  4M4V A;  2GVW A;  2FPB A;  4GJT A;  2Z32 A;  4FJ6 A;  3K36 A;  4FPF A;  1QBI A;  2VSK A;  3ALW A;  3HLI A;  1Z50 A;  2F10 A;  2P4O A;  4IQK A;  4AH4 A;  2RKC A;  4MWX A;  3LI5 A;  3FVZ A;  3AMR A;  1USR A;  4FPO B;  3V65 B;  4FOW A;  1W20 A;  3UC1 A;  3D11 A;  3DAS A;  2W5N A;  1N1T A;  2W8B B;  2WOZ A;  4XHX A;  4FPH A;  5FNU A;  5GX1 A;  3ADE A;  2VPJ A;  4K1H A;  3ZGD A;  4HZX A;  1DIM A;  2F26 A;  4HHO A;  1W0P A;  1N1S A;  3BYC A;  4XJZ A;  3S8Z A;  1Z4W A;  2YA5 A;  4M3M A;  2QWD A;  2VK5 A;  5D9B A;  1NNA A;  4B7R A;  2IAX A;  1L7H A;  4GZW A;  4FPG A;  3SLI A;  3TIA A;  4KS5 A;  3NO0 A;  1W21 A;  2QWF A;  4MZE A;  3S94 A;  2GVV A;  4KS1 A;  7NN9 A;  1ZI0 A;  1F8C A;  2YA7 A;  5FNR A;  2F25 A;  4FPJ A;  2AEQ A;  3H71 A;  1S0J A;  1B9V A;  4GZQ A;  1C5K A;  1E1A A;  2F12 A;  2VK6 A;  3IAX A;  4GN8 A;  2IAV A;  4K1I A;  2W20 A;  1E8U A;  2JKB A;  5FNS A;  4MC7 A;  5FZJ A;  5F9T A;  4L7C A;  3HLH A;  2QWK A;  5NN9 A;  4YW4 A;  2HT5 A;  2POO A;  3I1C A;  4XJ9 A;  3S2K A;  1ZGK A;  3FW0 A;  2F13 A;  4CPY A;  1IVC A;  5HUG A;  2VW2 A;  4N1B A;  3WW9 A;  2ISM A;  4XJ8 A;  3H6J A;  2ZW9 A;  2BAT A;  1A4Q A;  3TIC A;  1V3E A;  1V3B A;  1SO7 A;  2HT8 A;  2YA8 A;  3SOQ A;  3WN7 A;  3A71 A;  3KYA A;  4D8S A;  3TI5 A;  3O9J A;  4AHA A;  4Q6K A;  4MWL A;  1F8E A;  1ING A;  4FPL A;  3T1E A;  4K3Y A;  4B7N A;  3E5Z A;  3SRG A;  4FPY A;  2GVU A;  3HRP A;  1W0O A;  2IAO A;  3SIL A;  4KS2 A;  4C1Y A;  1IVG A;  4MWU A;  3SOB B;  2QWH A;  1OFZ A;  1K32 A;  5FZN A;  3KGG A;  4GN9 A;  4QN7 A;  2ZB5 A;  4YZ5 A;  3B7E A;  1MS1 A;  5HUM A;  4HZY A;  1N7D A;  3TI6 A;  1NN2 A;  4FOY A;  2F11 A;  4WA4 A;  2XZJ A;  3A72 A;  4MWY A;  4O5S A;  3VNG A;  4KS4 A;  5GTQ A;  1POO A;  1USX A;  3DR2 A;  3SRE A;  1EUT A;  4ZLR A;  4XIL A;  4G3N A;  1IVF A;  4HW6 A;  2FP8 A;  2SLI A;  2ZZK A;  1X2R A;  4FPE A;  4GEZ A;  4I00 A;  4M4U A;  3A9G A;  1N6D A;  1SLI A;  3H73 A;  4YY8 A;  4UOU A;  3B69 A;  1Q7F A;  3LI4 A;  1V0E A;  3U0S A;  1IJQ A;  2IAR A;  2VSM A;  1A4G A;  2VK7 A;  4MJV A;  4DG6 A;  3TC9 A;  4HZV A;  4B7M A;  1N1V A;  1N6F A;  1B9S A;  4CHB A;  4FPC A;  1E8T A;  1SNT A;  5D9C A;  1F8B A;  3JU4 A;  1MS5 A;  2YA4 A;  3SAL A;  2QWJ A;  1VCU A;  3S8V A;  5B2D A;  1CRU A;  4KS3 A;  3AMS A;  3INB A;  1INX A;  1EUR A;  2BF6 A;  4GNC A;  4WA3 A;  5EO7 A;  3CL0 A;  2F29 A;  2DSO A;  2H2U A;  1QLG A;  2BZD A;  2HTQ A;  4B7J A;  4WEF A;  4H53 A;  1WCS A;  5EX7 A;  1NNC A;  4XYX A;  4B7Q A;  3CL2 A;  3CKZ A;  1IVB A;  2HQS A;  1NCC N;  4ASC A;  3G4E A;  2HU0 A;  5D9D A;  4K1K A;  2W8B A;  1NMB N;  1NNB A;  4MWR A;  2OJH A;  3Q6P A;  4AGT A;  4CPM A;  1BJI A;  2QWB A;  4XOG A;  1F8D A;  2HTV A;  3K38 A;  2QWE A;  4XJU A;  4GZX A;  4YZ4 A;  1S18 A;  5HUN A;  4XJQ A;  4MX0 A;  2VWD A;  1WCQ A;  3CYE A;  3VNH A;  1IUB A;  3K39 A;  1INH A;  4FQ4 A;  4UF7 A;  2FP9 A;  2V91 A;  3V64 C;  1V0Z A;  4GN7 A;  4IFJ A;  1IVD A;  3L6V A;  1Z4X A;  3O4P A;  4XJA A;  1DIL A;  4QN6 A;  1NSD A;  5GX3 A;  4YZ2 A;  5M1Z A;  1V0F A;  1IUC A;  4ZGC A;  5GX2 A;  3BEQ A;  1E8V A;  4GNB A;  3D12 A;  4L7D A;  1V2I A;  2VW1 A;  4J9T A;  4IYG A;  4HZZ A;  4X6K A;  4C1Y B;  1XOG A;  1RWL A;  4YW1 A;  2F24 A;  2QWA A;  1KIT A;  1S1D A;  4XE9 A;  1EUU A;  2ZB6 A;  4XIO A;  1H6L A;  1B9T A;  4XJR A;  2A75 A;  1XOE A;  2VAQ A;  4R40 A;  4HHQ A;  4D52 B;  1NCA N;  2SIM A;  2XZI A;  1X2J A;  2X9M A;  4QNP A;  5FNQ A;  2FLU X;  4JF7 A;  2C4A A;  4YZ3 A;  1VCJ A;  2HTR A;  3GVJ A;  4CPO A;  3II7 A;  1NSC A;  1RWI A;  4O5T A;  1MS4 A;  2FHR A;  4CPL A;  4YW2 A;  4FP3 A;  2IAT A;  5F72 C;  3SAN A;  2DG0 A;  2IAW A;  4QN5 A;  2VVZ A;  4CPN A;  1SUU A;  4SLI A;  1IVE A;  4FOV A;  1Z4Z A;  2CML A;  2AGS A;  4L7B A;  5H47 A;  2DYH A;  3TI4 A;  1V3C A;  1L7F A;  4GB1 A;  3ZGC A;  1CVM A;  1SLL A;  3TI8 A;  4FOQ A;  1MZ6 A;  1A14 N;  1MS9 A;  3A9H A;  4CPZ A;  2HTW A;  1CRZ A;  2XCY A;  1NCB N;  2G8S A;  4NC5 A;  3OPZ A;  4X4A A;  4XMA A;  2HT7 A;  1MS3 A;  1INY A;  4FZH A;  4GDI A;  4CSD A;  4WA5 A;  1N1Y A;  5GX4 A;  3O9K A;  4XIK A;  2GVX A;  4NCS A;  2IAP A;  1MS0 A;  3TIB A;  4D4U A;  4BBW A;  3P5B L;  4MZA A;  6NN9 A;  1MZ5 A;  5CGJ A;  1S0I A;  2F28 A;  3K3A A;  2QWI A;  2GHS A;  3GVK A;  3PJQ A;  1NMA N;  4FPK A;  4YZ1 A;  4YW5 A;  4GDJ A;  1PJX A;  3V1S A;  4Q1U A;  2W38 A;  1NPE A;  2SIL A;  4XMI A;  4MWJ A;  2YA6 A;  1EUS A;  2XN4 A;  4CH9 A;  5HX0 A;  3SOV A;  4DGR A;  4A0P A;  2C4L A;  4IFN X;  3G4H A;  1CQ1 A;  3W09 A;  4MWQ A;  3GVL A;  2HU4 A;  3H72 A;  1V04 A;  4MWV A;  2FPC A;  2AH2 A;  1C9U A;  2HTY A;  4NN9 A;  4IMB A;  1W8N A;  1MWE A;  1N6E A;  2BER A;  2IAQ A;  4K1J A;  2F27 A;  4GZO A;  2HTU A;  2W5O A;  4HZW A;  4D52 C;  1INW A;  1Z4Y A;  3K37 A;  1L7G A;  2YDP A;  1NSB A;  5FNT A;  3NN9 A;  1W8O A;  5FWW A;  2AEP A;  2H2N A;  2IAU A;  1INV A;  2YDT A;  3LI3 A;  2QWC A;  4ZY3 A;  5GX5 A;  1MR5 A; 
#chains in the Genus database with same CATH homology
 4L7D A;  3VNG A;  2ZWA A;  4IQK A;  5FNS A;  4CHB A;  1U6D X;  5FZJ A;  4L7C A;  4L7B A;  4IFJ A;  2DYH A;  4ASC A;  2ZZK A;  1X2R A;  3ZGC A;  1ZGK A;  2WOZ A;  3II7 A;  2XN4 A;  5FZN A;  4CH9 A;  5FNU A;  4YY8 A;  5FNR A;  4IN4 A;  4N1B A;  3WDZ A;  3ADE A;  2VPJ A;  2ZW9 A;  4XMB A;  5FNT A;  5F72 C;  3ZGD A;  4IFL X;  4IFN X;  1X2J A;  2Z32 A;  4ZGC A;  3WN7 A;  5CGJ A;  4ZY3 A;  5FNQ A;  2FLU X;  3VNH A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...