1B9SA

Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
390
structure length
390
Chain Sequence
EPEWTYPRLSCQGSTFQKALLISPHRFGEIKGNSAPLIIREPFVACGPKECRHFALTHYAAQPGGYYNGTRKDRNKLRHLVSVKLGKIPTVENSIFHMAAWSGSACHDGREWTYIGVDGPDNDALVKIKYGEAYTDTYHSYAHNILRTQESACNCIGGDCYLMITDGSASGISKCRFLKIREGRIIKEILPTGRVEHTEECTCGFASNKTIECACRDNSYTAKRPFVKLNVETDTAEIRLMCTKTYLDTPRPDDGSIAGPCESNGDKWLGGIKGGFVHQRMASKIGRWYSRTMSKTNRMGMELYVRYDGDPWTDSDALTLSGVMVSIEEPGWYSFGFEIKDKKCDVPCIGIEMVHDGGKDTWHSAATAIYCLMGSGQLLWDTVTGVDMAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords PROTEIN (NEURAMINIDASE)
total genus 104
structure length 390
sequence length 390
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 1999-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00064 Neur Neuraminidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 1b9sA00
1MS1A 4MWWA 1BJIA 4BBWA 4CPYA 4MX0A 4X6KA 4MWLA 4QN7A 1L7FA 4MWRA 1EUTA 2HTWA 4XOGA 4FOQA 2RKCA 2VSMA 2YA6A 1EUSA 2VSKA 4FZHA 1V2IA 4M4UA 4XMIA 1Z4YA 3H6JA 1V3EA 1MS5A 1S0IA 4CPLA 4GZSA 4JF7A 4GJTA 4FPLA 3H73A 1B9VA 2C4AA 3K3AA 4FPEA 2QWAA 1MZ6A 2HTRA 4GDJA 1L7GA 4FPGA 4FVKA 1V3DA 4QN6A 5HUMA 3TI4A 1MS9A 1Z4WA 1MWEA 3W09A 1L7HA 4YZ1A 4CPZA 5HUGA 2F26A 2F25A 2HTVA 5M1ZA 2W5OA 2AGSA 3SANA 2AEPA 2SLIA 1NCCN 4XHXA 1XOEA 2F24A 3K39A 4GZQA 1INHA 5F9TA 3B7EA 1W21A 2QWDA 1WCQA 3B69A 3O9KA 1N1TA 1MS3A 4XIOA 3CYEA 4YZ5A 2XCYA 2VWDA 1INFA 3GVLA 4X49A 1NMCA 2F27A 4NN9A 5HUKA 3JU4A 4HZZA 2SIMA 3D11A 4WA4A 1EUUA 4HZYA 4XJ9A 1NSCA 2VK6A 4GZXA 4CPNA 2HT8A 3TICA 1V3CA 2BZDA 2YA5A 4YW2A 1NNAA 3ALWA 4YW1A 4GZOA 3CL2A 2QWEA 4FPKA 1N1VA 4WEGA 4XJUA 1DILA 1W0PA 2FHRA 2F0ZA 2QWKA 1USXA 4YZ3A 1INWA 1INVA 4XJWA 2W20A 4X4AA 4DGRA 4WA5A 2HT7A 4FPFA 4K3YA 2QWIA 1IVDA 3H71A 2VVZA 2VW1A 3CL0A 4QN4A 4X47A 1NCAN 2F12A 2HU4A 4GB1A 1EURA 1S0JA 2F11A 4FQ4A 3D12A 4YW3A 2W5NA 1A14N 4KS4A 1INXA 4MWQA 2B8HA 4WA3A 1IVEA 2QWHA 1A4QA 4XHBA 3SALA 2A75A 1V0ZA 3PJQA 5B2CA 1E8VA 4QNPA 3K38A 1IVFA 4YZ2A 4UF7A 4XJ8A 1SLLA 1NCBN 5JYYA 1NCDN 4HIZA 4FPCA 3A71A 4XMAA 3TI5A 3OPZA 1B9TA 1N1YA 3INBA 4YW5A 1VCJA 2YDPA 3TIBA 2HTYA 3O9JA 4MWUA 2C4LA 4YW4A 2QWGA 2HT5A 4M3MA 3GVJA 4GZTA 4XJQA 1IVCA 2X9MA 4FPHA 3K37A 1MR5A 4H53A 2VW0A 1NNBA 4D8SA 1NSBA 1DIMA 1NNCA 1MS8A 4XILA 4FP3A 2SILA 2YA8A 4MWVA 1F8EA 5HX0A 4YZ4A 1WCSA 3ALXA 3TIAA 1NMBN 4XIKA 4I00A 4WEFA 4K1HA 4H52A 1Z50A 5NN9A 4MJUA 1W8OA 1SNTA 4K1IA 4FPOB 1F8DA 5B2DA 1NMAN 1SLIA 1F8BA 4HZXA 5HUNA 2F29A 4XJRA 1INGA 2VW2A 2VK7A 1Z4VA 4FJ6A 3K36A 4HZVA 4K1KA 2YA7A 4NC5A 2XZIA 4MC7A 4B7RA 4KS5A 4FPYA 2HU0A 1A4GA 2CMLA 4FPJA 4XE9A 1Z4XA 4MZEA 2BERA 2W38A 1MS0A 4MWYA 4CPMA 1XOGA 4B7JA 2AH2A 1W0OA 2QWCA 2HTUA 3TI6A 3TI8A 1VCUA 7NN9A 4M4NA 3T1EA 4QN5A 4B7QA 4NCSA 3H72A 1F8CA 1IVBA 1E8UA 4MZAA 2BATA 4FOWA 4Q6KA 2VK5A 2F10A 1V0FA 4KS2A 4FP2A 3SLIA 2YDTA 3NSSA 3CKZA 4MWJA 4MWXA 1NN2A 1NSDA 4M4VA 4GZWA 3BEQA 4CPOA 1USRA 1V0EA 4B7MA 3A72A 4GZPA 3TI3A 4XJAA 2HTQA 2QWJA 4KS1A 4XJZA 1E8TA 3GVKA 4QN3A 4J9TA 1N1SA 6NN9A 2QWBA 2XZKA 2QWFA 4MJVA 1W20A 2JKBA 2XZJA 2ZB6A 3NN9A 2AEQA 1B9SA 4XYXA 2F13A 4GEZA 1V3BA 1SO7A 4HZWA 4B7NA 1Z4ZA 1MS4A 4KS3A 4FOYA 1W1XA 3SILA 2F28A 4GDIA 1IVGA 4K1JA 2YA4A 1W8NA 1INYA 2BF6A 4FOVA 2ZB5A 4SLIA 1KITA 1MZ5A
chains in the Genus database with same CATH superfamily
1MS1A 2ISMA 4MWWA 1BJIA 4BBWA 4CPYA 4MX0A 4X6KA 4MWLA 4QN7A 2FPCA 1L7FA 4MWRA 2QE8A 3FW0A 1EUTA 2HTWA 3DASA 4XOGA 4N1BA 3NO0A 4FOQA 2RKCA 2VSMA 2YA6A 5GX4A 1EUSA 2VSKA 4FZHA 1V2IA 4M4UA 4D52A 4XMIA 4L7CA 1Z4YA 3H6JA 1V3EA 1MS5A 1S0IA 4CPLA 4GZSA 4JF7A 1E1AA 1C5KA 4FPLA 4GJTA 4IQKA 4IYGA 3H73A 2IAXA 1B9VA 2C4AA 3K3AA 2H2NA 4FPEA 3VNGA 4IFNX 4GNCA 4AH4A 2QWAA 1MZ6A 1IUCA 3U0SA 2HTRA 4GDJA 1L7GA 4FPGA 4FVKA 1V3DA 4C1YB 4QN6A 5HUMA 1S18A 3TI4A 1MS9A 3V65B 2GVUA 1Z4WA 2IVZA 1MWEA 3W09A 1L7HA 3G4EA 4YZ1A 2GVVA 4CPZA 5HUGA 2F26A 2F25A 2HTVA 5EO7A 5M1ZA 2W5OA 1RWIA 5GTQA 5EX7A 2AGSA 3SANA 5D9CA 1ZGKA 2AEPA 2SLIA 1NCCN 4XHXA 1XOEA 3V64C 2F24A 3K39A 4ZGCA 4GZQA 1H6LA 1INHA 4IFJA 1OFZA 5F9TA 3B7EA 1W21A 2QWDA 1WCQA 3B69A 2Z32A 3A9HA 2ZZKA 3O9KA 1N1TA 1MS3A 4XIOA 3CYEA 4YZ5A 2XCYA 2VWDA 3BYCA 1INFA 2WOZA 3GVLA 4X49A 1NMCA 2F27A 4NN9A 5HUKA 3FVZA 3JU4A 4HZZA 2SIMA 3D11A 4WA4A 1EUUA 4HZYA 4XJ9A 2IAVA 1NSCA 2VK6A 2W8BB 4GZXA 2FLUX 2XN4A 5F72C 4CPNA 2HT8A 3TICA 1V3CA 1CRZA 2BZDA 2YA5A 2GVWA 4YW2A 1NNAA 3ALWA 4YW1A 2ZW9A 4GZOA 4JMLA 3CL2A 2QWEA 4CSDA 5FNUA 4FPKA 4O5SA 1N1VA 4WEGA 4XJUA 1DILA 1W0PA 3TC9A 4GN9A 2FHRA 2F0ZA 2QWKA 2VAQA 2GHSA 1USXA 4YZ3A 1N6EA 1INWA 1X2JA 1INVA 4XJWA 4D4UA 1C9UA 1WP5A 2W20A 1QLGA 4X4AA 3SOBB 4DGRA 4WA5A 2HT7A 3S8VA 1ZI0A 4FPFA 3AMSA 4K3YA 3ZGCA 2QWIA 1IVDA 3H71A 2VVZA 3UC1A 2VW1A 3CL0A 4QN4A 4X47A 1N7DA 1NCAN 2F12A 2HU4A 3Q6KA 4GB1A 1EURA 1QBIA 4HW6A 4AGIA 1S0JA 5FZNA 5CGJA 2F11A 4FQ4A 3D12A 4YW3A 2W5NA 3KGGA 1POOA 1A14N 4GNBA 2FP8A 4GNAA 4KS4A 1INXA 4MWQA 2B8HA 4AGTA 4WA3A 1IVEA 2QWHA 1A4QA 4XHBA 3SALA 2A75A 1V0ZA 2DG1A 2IAQA 3PJQA 5B2CA 3ZGDA 2H2UA 1E8VA 3P5BL 4QNPA 2IASA 4IFLX 3K38A 2V91A 1IVFA 4YZ2A 4UF7A 4XJ8A 1SUUA 4D52B 3Q6TA 1IUBA 3IAXA 4DG6A 1SLLA 5FWWA 1NCBN 2POOA 5JYYA 2IAPA 3A9GA 1NCDN 4HIZA 4FPCA 3A71A 4XMAA 5FNQA 3TI5A 1V04A 3OPZA 1B9TA 1N1YA 3INBA 3II7A 4YW5A 4HHQA 4CHBA 3LI3A 1VCJA 2IARA 3HLIA 4YY8A 2YDPA 3TIBA 1CRUA 2HTYA 3LI5A 3O9JA 2DSOA 4MWUA 2C4LA 2FP9A 4YW4A 2QWGA 2DG0A 2HQSA 2HT5A 4ZY3A 4M3MA 3I1CA 3GVJA 3O4PA 3V1SA 2DYHA 2OJHA 4GZTA 4XJQA 1IVCA 3SOVA 2X9MA 4FPHA 3K37A 1MR5A 4H53A 5H47A 2VW0A 1NNBA 4D8SA 1NSBA 1DIMA 4IN4A 1NNCA 1MS8A 4A0PA 4R40A 1K32A 1S1DA 4L7DA 3Q6PA 4XILA 4FP3A 2SILA 2YA8A 2IAUA 4MWVA 1F8EA 3WDZA 5HX0A 4YZ4A 5D9DA 1WCSA 3WN7A 3ALXA 3TIAA 1NMBN 1PJXA 4XIKA 4I00A 4WEFA 4K1HA 4GN8A 4H52A 1Z50A 5NN9A 4MJUA 1W8OA 3E5ZA 5EO8A 1SNTA 3LI4A 5GX2A 4K1IA 4Q1UA 4FPOB 2VPJA 1F8DA 5B2DA 1NMAN 4HHOA 1SLIA 4O5TA 1F8BA 3SREA 1X2RA 4HZXA 2F29A 4XJRA 5HUNA 5GX5A 1INGA 1Q7FA 2VW2A 3VNHA 2VK7A 1Z4VA 4FJ6A 3K36A 4HZVA 4K1KA 2YA7A 4NC5A 2XZIA 5FNTA 4MC7A 4B7RA 4C1YA 4KS5A 3AMRA 4FPYA 2HU0A 1A4GA 3ADEA 4L7BA 2CMLA 4FPJA 4XE9A 4ASCA 1Z4XA 4MZEA 4D52C 2BERA 2W38A 1MS0A 4MWYA 4CPMA 1XOGA 4B7JA 2AH2A 3L6VA 1W0OA 2QWCA 2HTUA 3TI6A 3TI8A 1VCUA 7NN9A 4XMBA 4GN7A 4M4NA 3T1EA 4QN5A 4B7QA 4NCSA 2G8SA 3H72A 3HRPA 1F8CA 1IVBA 1E8UA 4MZAA 2IATA 5FNRA 2BATA 4FOWA 4ZLRA 4Q6KA 2VK5A 2F10A 3S2KA 1V0FA 4KS2A 4FP2A 3SLIA 2YDTA 3NSSA 3CKZA 4MWJA 1N6FA 4MWXA 5D9BA 1NN2A 5GX3A 1NSDA 4M4VA 4GZWA 3BEQA 5GX1A 4CPOA 1USRA 4AHAA 2W8BA 1V0EA 1CVMA 4B7MA 3A72A 4GZPA 3S94A 3TI3A 4XJAA 2IAOA 2HTQA 2QWJA 1RWLA 3SOQA 4KS1A 4XJZA 1E8TA 1NPEA 3HLHA 2ZWAA 3GVKA 1U6DX 4QN3A 4J9TA 1CQ1A 1N1SA 1N6DA 6NN9A 2QWBA 2XZKA 4UOUA 2QWFA 4MJVA 2GVXA 1W20A 2IAWA 2JKBA 2XZJA 2ZB6A 3NN9A 4G3NA 2AEQA 3WW9A 1B9SA 4XYXA 2F13A 4IMBA 4GEZA 1V3BA 4PWZA 1SO7A 3DR2A 4HZWA 4B7NA 3S8ZA 5FNSA 3WWAA 1Z4ZA 4CH9A 1MS4A 4KS3A 2FPBA 2P4OA 4FOYA 3KYAA 1W1XA 3SILA 2F28A 4GDIA 1IVGA 4K1JA 2YA4A 3SRGA 1W8NA 1INYA 1IJQA 2BF6A 5FZJA 4FOVA 2ZB5A 4SLIA 1KITA 1MZ5A 3G4HA
chains in the Genus database with same CATH topology
1MS1A 4MWWA 1BJIA 4BBWA 4CPYA 4MX0A 4X6KA 4MWLA 4QN7A 1L7FA 4MWRA 1EUTA 2HTWA 4XOGA 4FOQA 2RKCA 2VSMA 2YA6A 1EUSA 2VSKA 4FZHA 1V2IA 4M4UA 4XMIA 1Z4YA 3H6JA 1V3EA 1MS5A 1S0IA 4CPLA 4GZSA 4JF7A 4GJTA 4FPLA 3H73A 1B9VA 2C4AA 3K3AA 2H2NA 4FPEA 2QWAA 1MZ6A 2HTRA 4GDJA 1L7GA 4FPGA 4FVKA 1V3DA 4QN6A 5HUMA 1S18A 3TI4A 1MS9A 1Z4WA 1MWEA 3W09A 1L7HA 4YZ1A 4CPZA 5HUGA 2F26A 2F25A 2HTVA 5M1ZA 2W5OA 2AGSA 3SANA 2AEPA 2SLIA 1NCCN 4XHXA 1XOEA 2F24A 3K39A 4GZQA 1INHA 5F9TA 3B7EA 1W21A 2QWDA 1WCQA 3B69A 3O9KA 1N1TA 1MS3A 4XIOA 3CYEA 4YZ5A 2XCYA 2VWDA 1INFA 3GVLA 4X49A 1NMCA 2F27A 4NN9A 5HUKA 3JU4A 4HZZA 2SIMA 3D11A 4WA4A 1EUUA 4HZYA 4XJ9A 1NSCA 2VK6A 4GZXA 4CPNA 2HT8A 3TICA 1V3CA 2BZDA 2YA5A 4YW2A 1NNAA 3ALWA 4YW1A 4GZOA 3CL2A 2QWEA 4FPKA 1N1VA 4WEGA 4XJUA 1DILA 1W0PA 2FHRA 2F0ZA 2QWKA 1USXA 4YZ3A 1INWA 1INVA 4XJWA 2W20A 4X4AA 4DGRA 4WA5A 2HT7A 4FPFA 4K3YA 2QWIA 1IVDA 3H71A 2VVZA 2VW1A 3CL0A 4QN4A 4X47A 1NCAN 2F12A 2HU4A 4GB1A 1EURA 1S0JA 2F11A 4FQ4A 3D12A 4YW3A 2W5NA 1A14N 4KS4A 1INXA 4MWQA 2B8HA 4WA3A 1IVEA 2QWHA 1A4QA 4XHBA 3SALA 2A75A 1V0ZA 3PJQA 5B2CA 2H2UA 1E8VA 4QNPA 3K38A 1IVFA 4YZ2A 4UF7A 4XJ8A 1SLLA 1NCBN 5JYYA 1NCDN 4HIZA 4FPCA 3A71A 4XMAA 3TI5A 3OPZA 1B9TA 1N1YA 3INBA 4YW5A 1VCJA 2YDPA 3TIBA 2HTYA 3O9JA 4MWUA 2C4LA 4YW4A 2QWGA 2HT5A 4M3MA 3GVJA 4GZTA 4XJQA 1IVCA 2X9MA 4FPHA 3K37A 1MR5A 4H53A 2VW0A 1NNBA 4D8SA 1NSBA 1DIMA 1NNCA 1MS8A 1S1DA 4XILA 4FP3A 2SILA 2YA8A 4MWVA 1F8EA 5HX0A 4YZ4A 1WCSA 3ALXA 3TIAA 1NMBN 4XIKA 4I00A 4WEFA 4K1HA 4H52A 1Z50A 5NN9A 4MJUA 1W8OA 1SNTA 4K1IA 4FPOB 1F8DA 5B2DA 1NMAN 1SLIA 1F8BA 4HZXA 5HUNA 2F29A 4XJRA 1INGA 2VW2A 2VK7A 1Z4VA 4FJ6A 3K36A 4HZVA 4K1KA 2YA7A 4NC5A 2XZIA 4MC7A 4B7RA 4KS5A 4FPYA 2HU0A 1A4GA 2CMLA 4FPJA 4XE9A 1Z4XA 4MZEA 2BERA 2W38A 1MS0A 4MWYA 4CPMA 1XOGA 4B7JA 2AH2A 1W0OA 2QWCA 2HTUA 3TI6A 3TI8A 1VCUA 7NN9A 4M4NA 3T1EA 4QN5A 4B7QA 4NCSA 3H72A 1F8CA 1IVBA 1E8UA 4MZAA 2BATA 4FOWA 4Q6KA 2VK5A 2F10A 1V0FA 4KS2A 4FP2A 3SLIA 2YDTA 3NSSA 3CKZA 4MWJA 4MWXA 1NN2A 1NSDA 4M4VA 4GZWA 3BEQA 4CPOA 1USRA 1V0EA 4B7MA 3A72A 4GZPA 3TI3A 4XJAA 2HTQA 2QWJA 4KS1A 4XJZA 1E8TA 3GVKA 4QN3A 4J9TA 1N1SA 6NN9A 2QWBA 2XZKA 2QWFA 4MJVA 1W20A 2JKBA 2XZJA 2ZB6A 3NN9A 2AEQA 1B9SA 4XYXA 2F13A 4GEZA 1V3BA 1SO7A 4HZWA 4B7NA 1Z4ZA 1MS4A 4KS3A 4FOYA 1W1XA 3SILA 2F28A 4GDIA 1IVGA 4K1JA 2YA4A 1W8NA 1INYA 2BF6A 4FOVA 2ZB5A 4SLIA 1KITA 1MZ5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MS1 A;  4MWW A;  1BJI A;  4BBW A;  4CPY A;  4MX0 A;  4X6K A;  4MWL A;  4QN7 A;  1L7F A;  4MWR A;  1EUT A;  2HTW A;  4XOG A;  4FOQ A;  2RKC A;  2VSM A;  2YA6 A;  1EUS A;  2VSK A;  4FZH A;  1V2I A;  4M4U A;  4XMI A;  1Z4Y A;  3H6J A;  1V3E A;  1MS5 A;  1S0I A;  4CPL A;  4GZS A;  4JF7 A;  4GJT A;  4FPL A;  3H73 A;  1B9V A;  2C4A A;  3K3A A;  4FPE A;  2QWA A;  1MZ6 A;  2HTR A;  4GDJ A;  1L7G A;  4FPG A;  4FVK A;  1V3D A;  4QN6 A;  5HUM A;  3TI4 A;  1MS9 A;  1Z4W A;  1MWE A;  3W09 A;  1L7H A;  4YZ1 A;  4CPZ A;  5HUG A;  2F26 A;  2F25 A;  2HTV A;  5M1Z A;  2W5O A;  2AGS A;  3SAN A;  2AEP A;  2SLI A;  1NCC N;  4XHX A;  1XOE A;  2F24 A;  3K39 A;  4GZQ A;  1INH A;  5F9T A;  3B7E A;  1W21 A;  2QWD A;  1WCQ A;  3B69 A;  3O9K A;  1N1T A;  1MS3 A;  4XIO A;  3CYE A;  4YZ5 A;  2XCY A;  2VWD A;  1INF A;  3GVL A;  4X49 A;  1NMC A;  2F27 A;  4NN9 A;  5HUK A;  3JU4 A;  4HZZ A;  2SIM A;  3D11 A;  4WA4 A;  1EUU A;  4HZY A;  4XJ9 A;  1NSC A;  2VK6 A;  4GZX A;  4CPN A;  2HT8 A;  3TIC A;  1V3C A;  2BZD A;  2YA5 A;  4YW2 A;  1NNA A;  3ALW A;  4YW1 A;  4GZO A;  3CL2 A;  2QWE A;  4FPK A;  1N1V A;  4WEG A;  4XJU A;  1DIL A;  1W0P A;  2FHR A;  2F0Z A;  2QWK A;  1USX A;  4YZ3 A;  1INW A;  1INV A;  4XJW A;  2W20 A;  4X4A A;  4DGR A;  4WA5 A;  2HT7 A;  4FPF A;  4K3Y A;  2QWI A;  1IVD A;  3H71 A;  2VVZ A;  2VW1 A;  3CL0 A;  4QN4 A;  4X47 A;  1NCA N;  2F12 A;  2HU4 A;  4GB1 A;  1EUR A;  1S0J A;  2F11 A;  4FQ4 A;  3D12 A;  4YW3 A;  2W5N A;  1A14 N;  4KS4 A;  1INX A;  4MWQ A;  2B8H A;  4WA3 A;  1IVE A;  2QWH A;  1A4Q A;  4XHB A;  3SAL A;  2A75 A;  1V0Z A;  3PJQ A;  5B2C A;  1E8V A;  4QNP A;  3K38 A;  1IVF A;  4YZ2 A;  4UF7 A;  4XJ8 A;  1SLL A;  1NCB N;  5JYY A;  1NCD N;  4HIZ A;  4FPC A;  3A71 A;  4XMA A;  3TI5 A;  3OPZ A;  1B9T A;  1N1Y A;  3INB A;  4YW5 A;  1VCJ A;  2YDP A;  3TIB A;  2HTY A;  3O9J A;  4MWU A;  2C4L A;  4YW4 A;  2QWG A;  2HT5 A;  4M3M A;  3GVJ A;  4GZT A;  4XJQ A;  1IVC A;  2X9M A;  4FPH A;  3K37 A;  1MR5 A;  4H53 A;  2VW0 A;  1NNB A;  4D8S A;  1NSB A;  1DIM A;  1NNC A;  1MS8 A;  4XIL A;  4FP3 A;  2SIL A;  2YA8 A;  4MWV A;  1F8E A;  5HX0 A;  4YZ4 A;  1WCS A;  3ALX A;  3TIA A;  1NMB N;  4XIK A;  4I00 A;  4WEF A;  4K1H A;  4H52 A;  1Z50 A;  5NN9 A;  4MJU A;  1W8O A;  1SNT A;  4K1I A;  4FPO B;  1F8D A;  5B2D A;  1NMA N;  1SLI A;  1F8B A;  4HZX A;  5HUN A;  2F29 A;  4XJR A;  1ING A;  2VW2 A;  2VK7 A;  1Z4V A;  4FJ6 A;  3K36 A;  4HZV A;  4K1K A;  2YA7 A;  4NC5 A;  2XZI A;  4MC7 A;  4B7R A;  4KS5 A;  4FPY A;  2HU0 A;  1A4G A;  2CML A;  4FPJ A;  4XE9 A;  1Z4X A;  4MZE A;  2BER A;  2W38 A;  1MS0 A;  4MWY A;  4CPM A;  1XOG A;  4B7J A;  2AH2 A;  1W0O A;  2QWC A;  2HTU A;  3TI6 A;  3TI8 A;  1VCU A;  7NN9 A;  4M4N A;  3T1E A;  4QN5 A;  4B7Q A;  4NCS A;  3H72 A;  1F8C A;  1IVB A;  1E8U A;  4MZA A;  2BAT A;  4FOW A;  4Q6K A;  2VK5 A;  2F10 A;  1V0F A;  4KS2 A;  4FP2 A;  3SLI A;  2YDT A;  3NSS A;  3CKZ A;  4MWJ A;  4MWX A;  1NN2 A;  1NSD A;  4M4V A;  4GZW A;  3BEQ A;  4CPO A;  1USR A;  1V0E A;  4B7M A;  3A72 A;  4GZP A;  3TI3 A;  4XJA A;  2HTQ A;  2QWJ A;  4KS1 A;  4XJZ A;  1E8T A;  3GVK A;  4QN3 A;  4J9T A;  1N1S A;  6NN9 A;  2QWB A;  2XZK A;  2QWF A;  4MJV A;  1W20 A;  2JKB A;  2XZJ A;  2ZB6 A;  3NN9 A;  2AEQ A;  1B9S A;  4XYX A;  2F13 A;  4GEZ A;  1V3B A;  1SO7 A;  4HZW A;  4B7N A;  1Z4Z A;  1MS4 A;  4KS3 A;  4FOY A;  1W1X A;  3SIL A;  2F28 A;  4GDI A;  1IVG A;  4K1J A;  2YA4 A;  1W8N A;  1INY A;  2BF6 A;  4FOV A;  2ZB5 A;  4SLI A;  1KIT A;  1MZ5 A; 
#chains in the Genus database with same CATH topology
 1MS1 A;  2ISM A;  4MWW A;  1BJI A;  4BBW A;  4CPY A;  4MX0 A;  4X6K A;  4MWL A;  4QN7 A;  2FPC A;  1L7F A;  4MWR A;  2QE8 A;  3FW0 A;  1EUT A;  2HTW A;  3DAS A;  4XOG A;  4N1B A;  3NO0 A;  4FOQ A;  2RKC A;  2VSM A;  2YA6 A;  5GX4 A;  1EUS A;  2VSK A;  4FZH A;  1V2I A;  4M4U A;  4D52 A;  4XMI A;  4L7C A;  1Z4Y A;  3H6J A;  1V3E A;  1MS5 A;  1S0I A;  4CPL A;  4GZS A;  4JF7 A;  1E1A A;  1C5K A;  4FPL A;  4GJT A;  4IQK A;  4IYG A;  3H73 A;  2IAX A;  1B9V A;  2C4A A;  3K3A A;  2H2N A;  4FPE A;  3VNG A;  4IFN X;  4GNC A;  4AH4 A;  2QWA A;  1MZ6 A;  1IUC A;  3U0S A;  2HTR A;  4GDJ A;  1L7G A;  4FPG A;  4FVK A;  1V3D A;  4C1Y B;  4QN6 A;  5HUM A;  1S18 A;  3TI4 A;  1MS9 A;  3V65 B;  2GVU A;  1Z4W A;  2IVZ A;  1MWE A;  3W09 A;  1L7H A;  3G4E A;  4YZ1 A;  2GVV A;  4CPZ A;  5HUG A;  2F26 A;  2F25 A;  2HTV A;  5EO7 A;  5M1Z A;  2W5O A;  1RWI A;  5GTQ A;  5EX7 A;  2AGS A;  3SAN A;  5D9C A;  1ZGK A;  2AEP A;  2SLI A;  1NCC N;  4XHX A;  1XOE A;  3V64 C;  2F24 A;  3K39 A;  4ZGC A;  4GZQ A;  1H6L A;  1INH A;  4IFJ A;  1OFZ A;  5F9T A;  3B7E A;  1W21 A;  2QWD A;  1WCQ A;  3B69 A;  2Z32 A;  3A9H A;  2ZZK A;  3O9K A;  1N1T A;  1MS3 A;  4XIO A;  3CYE A;  4YZ5 A;  2XCY A;  2VWD A;  3BYC A;  1INF A;  2WOZ A;  3GVL A;  4X49 A;  1NMC A;  2F27 A;  4NN9 A;  5HUK A;  3FVZ A;  3JU4 A;  4HZZ A;  2SIM A;  3D11 A;  4WA4 A;  1EUU A;  4HZY A;  4XJ9 A;  2IAV A;  1NSC A;  2VK6 A;  2W8B B;  4GZX A;  2FLU X;  2XN4 A;  5F72 C;  4CPN A;  2HT8 A;  3TIC A;  1V3C A;  1CRZ A;  2BZD A;  2YA5 A;  2GVW A;  4YW2 A;  1NNA A;  3ALW A;  4YW1 A;  2ZW9 A;  4GZO A;  4JML A;  3CL2 A;  2QWE A;  4CSD A;  5FNU A;  4FPK A;  4O5S A;  1N1V A;  4WEG A;  4XJU A;  1DIL A;  1W0P A;  3TC9 A;  4GN9 A;  2FHR A;  2F0Z A;  2QWK A;  2VAQ A;  2GHS A;  1USX A;  4YZ3 A;  1N6E A;  1INW A;  1X2J A;  1INV A;  4XJW A;  4D4U A;  1C9U A;  1WP5 A;  2W20 A;  1QLG A;  4X4A A;  3SOB B;  4DGR A;  4WA5 A;  2HT7 A;  3S8V A;  1ZI0 A;  4FPF A;  3AMS A;  4K3Y A;  3ZGC A;  2QWI A;  1IVD A;  3H71 A;  2VVZ A;  3UC1 A;  2VW1 A;  3CL0 A;  4QN4 A;  4X47 A;  1N7D A;  1NCA N;  2F12 A;  2HU4 A;  3Q6K A;  4GB1 A;  1EUR A;  1QBI A;  4HW6 A;  4AGI A;  1S0J A;  5FZN A;  5CGJ A;  2F11 A;  4FQ4 A;  3D12 A;  4YW3 A;  2W5N A;  3KGG A;  1POO A;  1A14 N;  4GNB A;  2FP8 A;  4GNA A;  4KS4 A;  1INX A;  4MWQ A;  2B8H A;  4AGT A;  4WA3 A;  1IVE A;  2QWH A;  1A4Q A;  4XHB A;  3SAL A;  2A75 A;  1V0Z A;  2DG1 A;  2IAQ A;  3PJQ A;  5B2C A;  3ZGD A;  2H2U A;  1E8V A;  3P5B L;  4QNP A;  2IAS A;  4IFL X;  3K38 A;  2V91 A;  1IVF A;  4YZ2 A;  4UF7 A;  4XJ8 A;  1SUU A;  4D52 B;  3Q6T A;  1IUB A;  3IAX A;  4DG6 A;  1SLL A;  5FWW A;  1NCB N;  2POO A;  5JYY A;  2IAP A;  3A9G A;  1NCD N;  4HIZ A;  4FPC A;  3A71 A;  4XMA A;  5FNQ A;  3TI5 A;  1V04 A;  3OPZ A;  1B9T A;  1N1Y A;  3INB A;  3II7 A;  4YW5 A;  4HHQ A;  4CHB A;  3LI3 A;  1VCJ A;  2IAR A;  3HLI A;  4YY8 A;  2YDP A;  3TIB A;  1CRU A;  2HTY A;  3LI5 A;  3O9J A;  2DSO A;  4MWU A;  2C4L A;  2FP9 A;  4YW4 A;  2QWG A;  2DG0 A;  2HQS A;  2HT5 A;  4ZY3 A;  4M3M A;  3I1C A;  3GVJ A;  3O4P A;  3V1S A;  2DYH A;  2OJH A;  4GZT A;  4XJQ A;  1IVC A;  3SOV A;  2X9M A;  4FPH A;  3K37 A;  1MR5 A;  4H53 A;  5H47 A;  2VW0 A;  1NNB A;  4D8S A;  1NSB A;  1DIM A;  4IN4 A;  1NNC A;  1MS8 A;  4A0P A;  4R40 A;  1K32 A;  1S1D A;  4L7D A;  3Q6P A;  4XIL A;  4FP3 A;  2SIL A;  2YA8 A;  2IAU A;  4MWV A;  1F8E A;  3WDZ A;  5HX0 A;  4YZ4 A;  5D9D A;  1WCS A;  3WN7 A;  3ALX A;  3TIA A;  1NMB N;  1PJX A;  4XIK A;  4I00 A;  4WEF A;  4K1H A;  4GN8 A;  4H52 A;  1Z50 A;  5NN9 A;  4MJU A;  1W8O A;  3E5Z A;  5EO8 A;  1SNT A;  3LI4 A;  5GX2 A;  4K1I A;  4Q1U A;  4FPO B;  2VPJ A;  1F8D A;  5B2D A;  1NMA N;  4HHO A;  1SLI A;  4O5T A;  1F8B A;  3SRE A;  1X2R A;  4HZX A;  2F29 A;  4XJR A;  5HUN A;  5GX5 A;  1ING A;  1Q7F A;  2VW2 A;  3VNH A;  2VK7 A;  1Z4V A;  4FJ6 A;  3K36 A;  4HZV A;  4K1K A;  2YA7 A;  4NC5 A;  2XZI A;  5FNT A;  4MC7 A;  4B7R A;  4C1Y A;  4KS5 A;  3AMR A;  4FPY A;  2HU0 A;  1A4G A;  3ADE A;  4L7B A;  2CML A;  4FPJ A;  4XE9 A;  4ASC A;  1Z4X A;  4MZE A;  4D52 C;  2BER A;  2W38 A;  1MS0 A;  4MWY A;  4CPM A;  1XOG A;  4B7J A;  2AH2 A;  3L6V A;  1W0O A;  2QWC A;  2HTU A;  3TI6 A;  3TI8 A;  1VCU A;  7NN9 A;  4XMB A;  4GN7 A;  4M4N A;  3T1E A;  4QN5 A;  4B7Q A;  4NCS A;  2G8S A;  3H72 A;  3HRP A;  1F8C A;  1IVB A;  1E8U A;  4MZA A;  2IAT A;  5FNR A;  2BAT A;  4FOW A;  4ZLR A;  4Q6K A;  2VK5 A;  2F10 A;  3S2K A;  1V0F A;  4KS2 A;  4FP2 A;  3SLI A;  2YDT A;  3NSS A;  3CKZ A;  4MWJ A;  1N6F A;  4MWX A;  5D9B A;  1NN2 A;  5GX3 A;  1NSD A;  4M4V A;  4GZW A;  3BEQ A;  5GX1 A;  4CPO A;  1USR A;  4AHA A;  2W8B A;  1V0E A;  1CVM A;  4B7M A;  3A72 A;  4GZP A;  3S94 A;  3TI3 A;  4XJA A;  2IAO A;  2HTQ A;  2QWJ A;  1RWL A;  3SOQ A;  4KS1 A;  4XJZ A;  1E8T A;  1NPE A;  3HLH A;  2ZWA A;  3GVK A;  1U6D X;  4QN3 A;  4J9T A;  1CQ1 A;  1N1S A;  1N6D A;  6NN9 A;  2QWB A;  2XZK A;  4UOU A;  2QWF A;  4MJV A;  2GVX A;  1W20 A;  2IAW A;  2JKB A;  2XZJ A;  2ZB6 A;  3NN9 A;  4G3N A;  2AEQ A;  3WW9 A;  1B9S A;  4XYX A;  2F13 A;  4IMB A;  4GEZ A;  1V3B A;  4PWZ A;  1SO7 A;  3DR2 A;  4HZW A;  4B7N A;  3S8Z A;  5FNS A;  3WWA A;  1Z4Z A;  4CH9 A;  1MS4 A;  4KS3 A;  2FPB A;  2P4O A;  4FOY A;  3KYA A;  1W1X A;  3SIL A;  2F28 A;  4GDI A;  1IVG A;  4K1J A;  2YA4 A;  3SRG A;  1W8N A;  1INY A;  1IJQ A;  2BF6 A;  5FZJ A;  4FOV A;  2ZB5 A;  4SLI A;  1KIT A;  1MZ5 A;  3G4H A; 
#chains in the Genus database with same CATH homology
 1MS1 A;  4MWW A;  1BJI A;  4BBW A;  4CPY A;  4MX0 A;  4X6K A;  4MWL A;  4QN7 A;  1L7F A;  4MWR A;  1EUT A;  2HTW A;  4XOG A;  4FOQ A;  2RKC A;  2VSM A;  2YA6 A;  1EUS A;  2VSK A;  4FZH A;  1V2I A;  4M4U A;  4XMI A;  1Z4Y A;  3H6J A;  1V3E A;  1MS5 A;  1S0I A;  4CPL A;  4GZS A;  4JF7 A;  4GJT A;  4FPL A;  3H73 A;  1B9V A;  2C4A A;  3K3A A;  2H2N A;  4FPE A;  2QWA A;  1MZ6 A;  2HTR A;  4GDJ A;  1L7G A;  4FPG A;  4FVK A;  1V3D A;  4QN6 A;  5HUM A;  1S18 A;  3TI4 A;  1MS9 A;  1Z4W A;  1MWE A;  3W09 A;  1L7H A;  4YZ1 A;  4CPZ A;  5HUG A;  2F26 A;  2F25 A;  2HTV A;  5M1Z A;  2W5O A;  2AGS A;  3SAN A;  2AEP A;  2SLI A;  1NCC N;  4XHX A;  1XOE A;  2F24 A;  3K39 A;  4GZQ A;  1INH A;  5F9T A;  3B7E A;  1W21 A;  2QWD A;  1WCQ A;  3B69 A;  3O9K A;  1N1T A;  1MS3 A;  4XIO A;  3CYE A;  4YZ5 A;  2XCY A;  2VWD A;  1INF A;  3GVL A;  4X49 A;  1NMC A;  2F27 A;  4NN9 A;  5HUK A;  3JU4 A;  4HZZ A;  2SIM A;  3D11 A;  4WA4 A;  1EUU A;  4HZY A;  4XJ9 A;  1NSC A;  2VK6 A;  4GZX A;  4CPN A;  2HT8 A;  3TIC A;  1V3C A;  2BZD A;  2YA5 A;  4YW2 A;  1NNA A;  3ALW A;  4YW1 A;  4GZO A;  3CL2 A;  2QWE A;  4FPK A;  1N1V A;  4WEG A;  4XJU A;  1DIL A;  1W0P A;  2FHR A;  2F0Z A;  2QWK A;  1USX A;  4YZ3 A;  1INW A;  1INV A;  4XJW A;  2W20 A;  4X4A A;  4DGR A;  4WA5 A;  2HT7 A;  4FPF A;  4K3Y A;  2QWI A;  1IVD A;  3H71 A;  2VVZ A;  2VW1 A;  3CL0 A;  4QN4 A;  4X47 A;  1NCA N;  2F12 A;  2HU4 A;  4GB1 A;  1EUR A;  1S0J A;  2F11 A;  4FQ4 A;  3D12 A;  4YW3 A;  2W5N A;  1A14 N;  4KS4 A;  1INX A;  4MWQ A;  2B8H A;  4WA3 A;  1IVE A;  2QWH A;  1A4Q A;  4XHB A;  3SAL A;  2A75 A;  1V0Z A;  3PJQ A;  5B2C A;  2H2U A;  1E8V A;  4QNP A;  3K38 A;  1IVF A;  4YZ2 A;  4UF7 A;  4XJ8 A;  1SLL A;  1NCB N;  5JYY A;  1NCD N;  4HIZ A;  4FPC A;  3A71 A;  4XMA A;  3TI5 A;  3OPZ A;  1B9T A;  1N1Y A;  3INB A;  4YW5 A;  1VCJ A;  2YDP A;  3TIB A;  2HTY A;  3O9J A;  4MWU A;  2C4L A;  4YW4 A;  2QWG A;  2HT5 A;  4M3M A;  3GVJ A;  4GZT A;  4XJQ A;  1IVC A;  2X9M A;  4FPH A;  3K37 A;  1MR5 A;  4H53 A;  2VW0 A;  1NNB A;  4D8S A;  1NSB A;  1DIM A;  1NNC A;  1MS8 A;  1S1D A;  4XIL A;  4FP3 A;  2SIL A;  2YA8 A;  4MWV A;  1F8E A;  5HX0 A;  4YZ4 A;  1WCS A;  3ALX A;  3TIA A;  1NMB N;  4XIK A;  4I00 A;  4WEF A;  4K1H A;  4H52 A;  1Z50 A;  5NN9 A;  4MJU A;  1W8O A;  1SNT A;  4K1I A;  4FPO B;  1F8D A;  5B2D A;  1NMA N;  1SLI A;  1F8B A;  4HZX A;  5HUN A;  2F29 A;  4XJR A;  1ING A;  2VW2 A;  2VK7 A;  1Z4V A;  4FJ6 A;  3K36 A;  4HZV A;  4K1K A;  2YA7 A;  4NC5 A;  2XZI A;  4MC7 A;  4B7R A;  4KS5 A;  4FPY A;  2HU0 A;  1A4G A;  2CML A;  4FPJ A;  4XE9 A;  1Z4X A;  4MZE A;  2BER A;  2W38 A;  1MS0 A;  4MWY A;  4CPM A;  1XOG A;  4B7J A;  2AH2 A;  1W0O A;  2QWC A;  2HTU A;  3TI6 A;  3TI8 A;  1VCU A;  7NN9 A;  4M4N A;  3T1E A;  4QN5 A;  4B7Q A;  4NCS A;  3H72 A;  1F8C A;  1IVB A;  1E8U A;  4MZA A;  2BAT A;  4FOW A;  4Q6K A;  2VK5 A;  2F10 A;  1V0F A;  4KS2 A;  4FP2 A;  3SLI A;  2YDT A;  3NSS A;  3CKZ A;  4MWJ A;  4MWX A;  1NN2 A;  1NSD A;  4M4V A;  4GZW A;  3BEQ A;  4CPO A;  1USR A;  1V0E A;  4B7M A;  3A72 A;  4GZP A;  3TI3 A;  4XJA A;  2HTQ A;  2QWJ A;  4KS1 A;  4XJZ A;  1E8T A;  3GVK A;  4QN3 A;  4J9T A;  1N1S A;  6NN9 A;  2QWB A;  2XZK A;  2QWF A;  4MJV A;  1W20 A;  2JKB A;  2XZJ A;  2ZB6 A;  3NN9 A;  2AEQ A;  1B9S A;  4XYX A;  2F13 A;  4GEZ A;  1V3B A;  1SO7 A;  4HZW A;  4B7N A;  1Z4Z A;  1MS4 A;  4KS3 A;  4FOY A;  1W1X A;  3SIL A;  2F28 A;  4GDI A;  1IVG A;  4K1J A;  2YA4 A;  1W8N A;  1INY A;  2BF6 A;  4FOV A;  2ZB5 A;  4SLI A;  1KIT A;  1MZ5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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