1VCUA

Structure of the human cytosolic sialidase neu2 in complex with the inhibitor dana
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
377
structure length
370
Chain Sequence
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLNDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Human Cytosolic Sialidase Neu2: EVIDENCE FOR THE DYNAMIC NATURE OF SUBSTRATE RECOGNITION
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Sialidase 2
total genus 101
structure length 370
sequence length 377
chains with identical sequence B
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2004-03-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13088 BNR_2 BNR repeat-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 1vcuA00
1W21A 2HU0A 1IVBA 4HIZA 1EURA 4K1JA 4YW1A 1MS4A 2BATA 1SLLA 4MWWA 4FPOB 2RKCA 1L7GA 2VK7A 4JF7A 1NMAN 2BZDA 2YA7A 1NCBN 1EUSA 3TI3A 3O9KA 2HT7A 1V2IA 4GB1A 3INBA 2VWDA 4HZYA 1MZ5A 1MS8A 1Z4ZA 1SLIA 4FVKA 1B9TA 1F8DA 4GZTA 5M1ZA 1E8VA 4FP3A 2F27A 4FPJA 1MS3A 1VCUA 4M4VA 3A71A 4Q6KA 1MS1A 2F24A 4K1KA 3K38A 1INVA 3CL2A 4XJZA 1N1YA 4FZHA 2F11A 5JYYA 4FPHA 1V3DA 1MS9A 1V0EA 4FP2A 1NMBN 2JKBA 2AEQA 3K36A 4GZOA 1XOGA 2VSMA 4MWQA 1Z4WA 1NSCA 4K1IA 4QN7A 4H52A 1INXA 4QN3A 1INFA 2XZIA 5B2CA 2QWCA 4YW4A 3NN9A 3GVJA 5HX0A 4MWJA 3OPZA 2SIMA 1XOEA 3JU4A 4FPKA 4NCSA 4B7NA 2W5NA 2YA6A 4HZWA 4FPYA 1MWEA 2F25A 2VSKA 1WCQA 1B9VA 4GEZA 4XIOA 3GVKA 3A72A 4XMAA 2VVZA 1SO7A 2YA4A 4YZ3A 4KS3A 4MWVA 1IVEA 4M4NA 2XZJA 3TI6A 2YA5A 1INWA 1INGA 1F8EA 1NSDA 4CPZA 7NN9A 4YZ5A 4XYXA 4FPCA 4GDIA 4B7RA 1EUUA 4NN9A 3K39A 4XHBA 4D8SA 2C4LA 3TICA 1BJIA 4MWLA 1F8CA 4GJTA 1NMCA 4CPMA 4MWRA 3BEQA 4YW5A 1W1XA 3TIAA 3SILA 2QWHA 4CPLA 1WCSA 3TI8A 4QN4A 1N1SA 3B7EA 4XJWA 2F13A 2HT5A 2QWFA 3SALA 4B7QA 4KS1A 2YA8A 1VCJA 4FPLA 1NCDN 2YDPA 4FPEA 2HTVA 2AGSA 4FOYA 4YZ2A 2F28A 4XJQA 3PJQA 1Z4YA 2W5OA 1Z4XA 2AEPA 3D11A 2VW0A 1V3CA 4HZVA 1NNBA 2HT8A 4DGRA 1INHA 1MR5A 2QWJA 4WA4A 4FOQA 3H6JA 4UF7A 5HUKA 1Z50A 2ZB5A 1A4GA 1NNCA 4M4UA 2HU4A 2F29A 4FPFA 4M3MA 3SANA 2C4AA 2YDTA 4X47A 4QNPA 4B7JA 4YW3A 6NN9A 1V3BA 3K3AA 1N1TA 4MX0A 2VK6A 3W09A 3CL0A 1NCAN 4KS5A 4XIKA 1IVGA 1Z4VA 2HTUA 4MWXA 2QWDA 1B9SA 2FHRA 2HTWA 2SILA 3TI5A 3GVLA 1USRA 3H73A 4XE9A 1MZ6A 4XHXA 3CKZA 4FPGA 4MZAA 2ZB6A 1F8BA 4XILA 2HTRA 1W0OA 1W0PA 2F10A 5NN9A 3ALWA 4SLIA 1W20A 4WA5A 1L7FA 1DILA 1L7HA 4CPYA 4K3YA 4BBWA 4WEGA 4XJ9A 3NSSA 1V3EA 4YZ1A 1SNTA 3H72A 2BF6A 3SLIA 2VW2A 4X6KA 2VW1A 2W20A 3CYEA 1V0FA 4QN5A 4CPNA 4H53A 4WA3A 1IVFA 4B7MA 2QWBA 1S0JA 2BERA 4XJUA 4XMIA 4FOVA 4I00A 1INYA 2QWGA 2QWKA 2F26A 4FJ6A 3B69A 2AH2A 3O9JA 5HUGA 1MS5A 4HZXA 4GDJA 5B2DA 1W8NA 4YW2A 2HTYA 2XZKA 4GZWA 2QWIA 3TI4A 1NCCN 1A14N 3D12A 1USXA 2B8HA 2W38A 1E8TA 4MZEA 4K1HA 1IVDA 1W8OA 1EUTA 3H71A 2CMLA 3K37A 1NNAA 2SLIA 3TIBA 1V0ZA 4X49A 4GZSA 2X9MA 4YZ4A 4HZZA 4FQ4A 4MC7A 3ALXA 4MWYA 2HTQA 2XCYA 4MJVA 2QWEA 4FOWA 4XJAA 1KITA 3T1EA 2A75A 1IVCA 4GZQA 4GZPA 1DIMA 4KS2A 4X4AA 2F12A 1N1VA 4MWUA 1S0IA 5F9TA 1MS0A 4XJ8A 4GZXA 2VK5A 1NN2A 5HUMA 4XOGA 1NSBA 4J9TA 1E8UA 4MJUA 4NC5A 4XJRA 4QN6A 5HUNA 4KS4A 2F0ZA 1A4QA 4WEFA 2QWAA 4CPOA
chains in the Genus database with same CATH superfamily
1W21A 2HU0A 1IVBA 4HIZA 4ZY3A 1EURA 4K1JA 5FNTA 1N7DA 4GN8A 4YW1A 1MS4A 2BATA 1SLLA 4MWWA 4FPOB 1POOA 2RKCA 1L7GA 2IVZA 2VK7A 4JF7A 1Q7FA 1NMAN 2BZDA 2YA7A 3SOVA 1NCBN 3WDZA 1EUSA 3TI3A 2IAOA 1SUUA 2HT7A 3O9KA 2IAUA 1V2IA 3G4HA 4GB1A 1QBIA 2GHSA 2IATA 3INBA 2VWDA 2OJHA 1S18A 4HZYA 3ZGDA 1MZ5A 5EO8A 5GX2A 1MS8A 1Z4ZA 1SLIA 4FVKA 1ZGKA 1B9TA 1F8DA 4GZTA 5M1ZA 1C9UA 1E8VA 4C1YB 4FP3A 2F27A 2FP8A 4FPJA 4HHQA 1MS3A 1VCUA 2IAXA 3A71A 4M4VA 4Q6KA 1MS1A 2F24A 4K1KA 3K38A 3IAXA 1INVA 3CL2A 4XJZA 1N1YA 4FZHA 2F11A 5JYYA 5GX3A 3TC9A 2W8BB 3V64C 4FPHA 1V3DA 1MS9A 1V0EA 4FP2A 1NMBN 2H2NA 2JKBA 2AEQA 3K36A 4O5TA 4YY8A 4GZOA 1XOGA 2GVXA 2VSMA 3BYCA 4MWQA 1Z4WA 1NSCA 4K1IA 4QN7A 1QLGA 4H52A 1INXA 4QN3A 1INFA 2XZIA 5B2CA 2QWCA 5FNQA 4IFNX 4YW4A 3NN9A 3GVJA 5FNUA 5HX0A 4MWJA 3OPZA 2SIMA 1XOEA 2ZZKA 3JU4A 4FPKA 4NCSA 4B7NA 2W5NA 2YA6A 2VAQA 3WN7A 5GX1A 1N6EA 1MWEA 4FPYA 4HZWA 4R40A 2DG0A 3FVZA 2F25A 2VSKA 1WCQA 1B9VA 4GEZA 4XIOA 3GVKA 4ASCA 3A72A 4XMAA 2VVZA 1SO7A 2YA4A 4YZ3A 4L7BA 4KS3A 2ZWAA 1WP5A 1RWLA 4MWVA 1IVEA 4M4NA 2XZJA 3TI6A 3A9HA 2YA5A 1INWA 1INGA 1F8EA 4GNBA 1NSDA 4CPZA 2HQSA 7NN9A 3SOBB 4YZ5A 4XYXA 4FPCA 3WWAA 4GDIA 4B7RA 5FNSA 1EUUA 5FZNA 4NN9A 4AGTA 3K39A 4XHBA 3S2KA 4D8SA 2C4LA 3TICA 1BJIA 4MWLA 1F8CA 3ZGCA 4GJTA 1NMCA 4CPMA 4MWRA 3G4EA 3BEQA 4YW5A 1W1XA 3TIAA 2DSOA 3SILA 4AGIA 2QWHA 4CPLA 1WCSA 3TI8A 3NO0A 4QN4A 1N1SA 3B7EA 3WW9A 3A9GA 4XJWA 2F13A 3Q6KA 2HT5A 2QWFA 3SALA 4B7QA 3V1SA 4KS1A 2QE8A 1S1DA 2YA8A 4CH9A 1IJQA 2DG1A 1VCJA 4FPLA 4IYGA 1NCDN 2YDPA 2GVVA 4FPEA 2HTVA 5F72C 3DR2A 2IAQA 2AGSA 4IFLX 4FOYA 4YZ2A 2F28A 4GNCA 4GN9A 4XJQA 1X2JA 1N6FA 3PJQA 1Z4YA 2W5OA 1Z4XA 3LI4A 2AEPA 2WOZA 3D11A 2DYHA 2VW0A 1V3CA 3FW0A 2IAPA 4HZVA 2GVWA 1NNBA 5FZJA 2HT8A 1ZI0A 4DGRA 1INHA 4G3NA 1MR5A 2QWJA 4WA4A 4FOQA 3H6JA 4UF7A 1E1AA 4N1BA 5HUKA 1Z50A 2ZB5A 1A4GA 1NNCA 4M4UA 2HU4A 2F29A 4FPFA 4M3MA 3SANA 4L7CA 1CVMA 3AMRA 2C4AA 2YDTA 4X47A 4QNPA 4B7JA 1CRZA 4YW3A 3HLIA 6NN9A 1V3BA 3K3AA 1N1TA 2FLUX 4MX0A 2VK6A 3W09A 3CL0A 4C1YA 4ZGCA 1NCAN 2POOA 4KS5A 4IN4A 4XIKA 1IVGA 1Z4VA 2HTUA 3O4PA 5GX4A 4MWXA 4GNAA 2VPJA 2QWDA 1B9SA 2FHRA 2HTWA 3S94A 4D52C 2SILA 3TI5A 4Q1UA 4HHOA 1U6DX 3GVLA 2GVUA 1K32A 1USRA 3VNHA 3H73A 2XN4A 4XE9A 1MZ6A 4XHXA 3CKZA 4FPGA 4MZAA 3KGGA 2W8BA 2ZB6A 4O5SA 4PWZA 1F8BA 2FPBA 4XMBA 4XILA 2HTRA 1W0OA 2IAVA 2FP9A 3S8ZA 4ZLRA 1W0PA 2F10A 5NN9A 3ALWA 4SLIA 1W20A 2H2UA 4WA5A 2Z32A 1L7FA 3DASA 1DILA 1L7HA 4CPYA 4K3YA 4BBWA 4WEGA 4XJ9A 4IFJA 3NSSA 1V3EA 4YZ1A 1SNTA 4D52B 3SOQA 3H72A 2BF6A 4D4UA 1H6LA 3SLIA 2VW2A 4X6KA 2VW1A 5D9BA 2W20A 3CYEA 1V0FA 4QN5A 4CPNA 4H53A 4WA3A 1IVFA 5EX7A 5FWWA 1X2RA 3VNGA 4B7MA 3LI5A 2QWBA 1S0JA 2BERA 3V65B 1CQ1A 4XJUA 4XMIA 4FOVA 4I00A 1INYA 4JMLA 2QWGA 2IARA 2QWKA 4CSDA 5D9CA 2F26A 4FJ6A 3B69A 2AH2A 3O9JA 1V04A 4IMBA 4AH4A 5HUGA 3HRPA 1MS5A 4HZXA 4GDJA 5B2DA 3LI3A 1W8NA 4L7DA 4YW2A 2HTYA 4UOUA 3E5ZA 2XZKA 4GZWA 3SREA 2QWIA 3TI4A 1NCCN 1A14N 3Q6TA 3D12A 1N6DA 3HLHA 1PJXA 4D52A 1USXA 2B8HA 2W38A 1E8TA 2P4OA 4MZEA 5D9DA 1IUCA 4K1HA 1IVDA 1W8OA 1EUTA 4AHAA 3H71A 2ISMA 2CMLA 3K37A 1NNAA 2SLIA 3TIBA 5GTQA 1V0ZA 3KYAA 3U0SA 4X49A 5H47A 4GZSA 3L6VA 2X9MA 3UC1A 1RWIA 4YZ4A 4IQKA 3SRGA 4HZZA 2IAWA 3Q6PA 4FQ4A 3II7A 4GN7A 4MC7A 3ALXA 4MWYA 2HTQA 2XCYA 4MJVA 2QWEA 4FOWA 1NPEA 4XJAA 1KITA 3T1EA 2A75A 1IVCA 4GZQA 3AMSA 1IUBA 4GZPA 1DIMA 4KS2A 3P5BL 4X4AA 2F12A 4HW6A 1N1VA 4MWUA 1S0IA 5F9TA 1MS0A 2FPCA 4XJ8A 5CGJA 4GZXA 2VK5A 1NN2A 1CRUA 5FNRA 4A0PA 3I1CA 2G8SA 5HUMA 4XOGA 1NSBA 4J9TA 1E8UA 4MJUA 1C5KA 4NC5A 4XJRA 4QN6A 2ZW9A 1OFZA 5HUNA 4KS4A 2F0ZA 2V91A 1A4QA 4DG6A 4CHBA 3ADEA 4WEFA 3S8VA 2IASA 2QWAA 5EO7A 5GX5A 4CPOA
chains in the Genus database with same CATH topology
1W21A 2HU0A 1IVBA 4HIZA 1EURA 4K1JA 4YW1A 1MS4A 2BATA 1SLLA 4MWWA 4FPOB 2RKCA 1L7GA 2VK7A 4JF7A 1NMAN 2BZDA 2YA7A 1NCBN 1EUSA 3TI3A 3O9KA 2HT7A 1V2IA 4GB1A 3INBA 2VWDA 1S18A 4HZYA 1MZ5A 1MS8A 1Z4ZA 1SLIA 4FVKA 1B9TA 1F8DA 4GZTA 5M1ZA 1E8VA 4FP3A 2F27A 4FPJA 1MS3A 1VCUA 4M4VA 3A71A 4Q6KA 1MS1A 2F24A 4K1KA 3K38A 1INVA 3CL2A 4XJZA 1N1YA 4FZHA 2F11A 5JYYA 4FPHA 1V3DA 1MS9A 1V0EA 4FP2A 1NMBN 2H2NA 2JKBA 2AEQA 3K36A 4GZOA 1XOGA 2VSMA 4MWQA 1Z4WA 1NSCA 4K1IA 4QN7A 4H52A 1INXA 4QN3A 1INFA 2XZIA 5B2CA 2QWCA 4YW4A 3NN9A 3GVJA 5HX0A 4MWJA 3OPZA 2SIMA 1XOEA 3JU4A 4FPKA 4NCSA 4B7NA 2W5NA 2YA6A 4HZWA 4FPYA 1MWEA 2F25A 2VSKA 1WCQA 1B9VA 4GEZA 4XIOA 3GVKA 3A72A 4XMAA 2VVZA 1SO7A 2YA4A 4YZ3A 4KS3A 4MWVA 1IVEA 4M4NA 2XZJA 3TI6A 2YA5A 1INWA 1INGA 1F8EA 1NSDA 4CPZA 7NN9A 4YZ5A 4XYXA 4FPCA 4GDIA 4B7RA 1EUUA 4NN9A 3K39A 4XHBA 4D8SA 2C4LA 3TICA 1BJIA 4MWLA 1F8CA 4GJTA 1NMCA 4CPMA 4MWRA 3BEQA 4YW5A 1W1XA 3TIAA 3SILA 2QWHA 4CPLA 1WCSA 3TI8A 4QN4A 1N1SA 3B7EA 4XJWA 2F13A 2HT5A 2QWFA 3SALA 4B7QA 4KS1A 1S1DA 2YA8A 1VCJA 4FPLA 1NCDN 2YDPA 4FPEA 2HTVA 2AGSA 4FOYA 4YZ2A 2F28A 4XJQA 3PJQA 1Z4YA 2W5OA 1Z4XA 2AEPA 3D11A 2VW0A 1V3CA 4HZVA 1NNBA 2HT8A 4DGRA 1INHA 1MR5A 2QWJA 4WA4A 4FOQA 3H6JA 4UF7A 5HUKA 1Z50A 2ZB5A 1A4GA 1NNCA 4M4UA 2HU4A 2F29A 4FPFA 4M3MA 3SANA 2C4AA 2YDTA 4X47A 4QNPA 4B7JA 4YW3A 6NN9A 1V3BA 3K3AA 1N1TA 4MX0A 2VK6A 3W09A 3CL0A 1NCAN 4KS5A 4XIKA 1IVGA 1Z4VA 2HTUA 4MWXA 2QWDA 1B9SA 2FHRA 2HTWA 2SILA 3TI5A 3GVLA 1USRA 3H73A 4XE9A 1MZ6A 4XHXA 3CKZA 4FPGA 4MZAA 2ZB6A 1F8BA 4XILA 2HTRA 1W0OA 1W0PA 2F10A 5NN9A 3ALWA 4SLIA 1W20A 2H2UA 4WA5A 1L7FA 1DILA 1L7HA 4CPYA 4K3YA 4BBWA 4WEGA 4XJ9A 3NSSA 1V3EA 4YZ1A 1SNTA 3H72A 2BF6A 3SLIA 2VW2A 4X6KA 2VW1A 2W20A 3CYEA 1V0FA 4QN5A 4CPNA 4H53A 4WA3A 1IVFA 4B7MA 2QWBA 1S0JA 2BERA 4XJUA 4XMIA 4FOVA 4I00A 1INYA 2QWGA 2QWKA 2F26A 4FJ6A 3B69A 2AH2A 3O9JA 5HUGA 1MS5A 4HZXA 4GDJA 5B2DA 1W8NA 4YW2A 2HTYA 2XZKA 4GZWA 2QWIA 3TI4A 1NCCN 1A14N 3D12A 1USXA 2B8HA 2W38A 1E8TA 4MZEA 4K1HA 1IVDA 1W8OA 1EUTA 3H71A 2CMLA 3K37A 1NNAA 2SLIA 3TIBA 1V0ZA 4X49A 4GZSA 2X9MA 4YZ4A 4HZZA 4FQ4A 4MC7A 3ALXA 4MWYA 2HTQA 2XCYA 4MJVA 2QWEA 4FOWA 4XJAA 1KITA 3T1EA 2A75A 1IVCA 4GZQA 4GZPA 1DIMA 4KS2A 4X4AA 2F12A 1N1VA 4MWUA 1S0IA 5F9TA 1MS0A 4XJ8A 4GZXA 2VK5A 1NN2A 5HUMA 4XOGA 1NSBA 4J9TA 1E8UA 4MJUA 4NC5A 4XJRA 4QN6A 5HUNA 4KS4A 2F0ZA 1A4QA 4WEFA 2QWAA 4CPOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W21 A;  2HU0 A;  1IVB A;  4HIZ A;  1EUR A;  4K1J A;  4YW1 A;  1MS4 A;  2BAT A;  1SLL A;  4MWW A;  4FPO B;  2RKC A;  1L7G A;  2VK7 A;  4JF7 A;  1NMA N;  2BZD A;  2YA7 A;  1NCB N;  1EUS A;  3TI3 A;  3O9K A;  2HT7 A;  1V2I A;  4GB1 A;  3INB A;  2VWD A;  4HZY A;  1MZ5 A;  1MS8 A;  1Z4Z A;  1SLI A;  4FVK A;  1B9T A;  1F8D A;  4GZT A;  5M1Z A;  1E8V A;  4FP3 A;  2F27 A;  4FPJ A;  1MS3 A;  1VCU A;  4M4V A;  3A71 A;  4Q6K A;  1MS1 A;  2F24 A;  4K1K A;  3K38 A;  1INV A;  3CL2 A;  4XJZ A;  1N1Y A;  4FZH A;  2F11 A;  5JYY A;  4FPH A;  1V3D A;  1MS9 A;  1V0E A;  4FP2 A;  1NMB N;  2JKB A;  2AEQ A;  3K36 A;  4GZO A;  1XOG A;  2VSM A;  4MWQ A;  1Z4W A;  1NSC A;  4K1I A;  4QN7 A;  4H52 A;  1INX A;  4QN3 A;  1INF A;  2XZI A;  5B2C A;  2QWC A;  4YW4 A;  3NN9 A;  3GVJ A;  5HX0 A;  4MWJ A;  3OPZ A;  2SIM A;  1XOE A;  3JU4 A;  4FPK A;  4NCS A;  4B7N A;  2W5N A;  2YA6 A;  4HZW A;  4FPY A;  1MWE A;  2F25 A;  2VSK A;  1WCQ A;  1B9V A;  4GEZ A;  4XIO A;  3GVK A;  3A72 A;  4XMA A;  2VVZ A;  1SO7 A;  2YA4 A;  4YZ3 A;  4KS3 A;  4MWV A;  1IVE A;  4M4N A;  2XZJ A;  3TI6 A;  2YA5 A;  1INW A;  1ING A;  1F8E A;  1NSD A;  4CPZ A;  7NN9 A;  4YZ5 A;  4XYX A;  4FPC A;  4GDI A;  4B7R A;  1EUU A;  4NN9 A;  3K39 A;  4XHB A;  4D8S A;  2C4L A;  3TIC A;  1BJI A;  4MWL A;  1F8C A;  4GJT A;  1NMC A;  4CPM A;  4MWR A;  3BEQ A;  4YW5 A;  1W1X A;  3TIA A;  3SIL A;  2QWH A;  4CPL A;  1WCS A;  3TI8 A;  4QN4 A;  1N1S A;  3B7E A;  4XJW A;  2F13 A;  2HT5 A;  2QWF A;  3SAL A;  4B7Q A;  4KS1 A;  2YA8 A;  1VCJ A;  4FPL A;  1NCD N;  2YDP A;  4FPE A;  2HTV A;  2AGS A;  4FOY A;  4YZ2 A;  2F28 A;  4XJQ A;  3PJQ A;  1Z4Y A;  2W5O A;  1Z4X A;  2AEP A;  3D11 A;  2VW0 A;  1V3C A;  4HZV A;  1NNB A;  2HT8 A;  4DGR A;  1INH A;  1MR5 A;  2QWJ A;  4WA4 A;  4FOQ A;  3H6J A;  4UF7 A;  5HUK A;  1Z50 A;  2ZB5 A;  1A4G A;  1NNC A;  4M4U A;  2HU4 A;  2F29 A;  4FPF A;  4M3M A;  3SAN A;  2C4A A;  2YDT A;  4X47 A;  4QNP A;  4B7J A;  4YW3 A;  6NN9 A;  1V3B A;  3K3A A;  1N1T A;  4MX0 A;  2VK6 A;  3W09 A;  3CL0 A;  1NCA N;  4KS5 A;  4XIK A;  1IVG A;  1Z4V A;  2HTU A;  4MWX A;  2QWD A;  1B9S A;  2FHR A;  2HTW A;  2SIL A;  3TI5 A;  3GVL A;  1USR A;  3H73 A;  4XE9 A;  1MZ6 A;  4XHX A;  3CKZ A;  4FPG A;  4MZA A;  2ZB6 A;  1F8B A;  4XIL A;  2HTR A;  1W0O A;  1W0P A;  2F10 A;  5NN9 A;  3ALW A;  4SLI A;  1W20 A;  4WA5 A;  1L7F A;  1DIL A;  1L7H A;  4CPY A;  4K3Y A;  4BBW A;  4WEG A;  4XJ9 A;  3NSS A;  1V3E A;  4YZ1 A;  1SNT A;  3H72 A;  2BF6 A;  3SLI A;  2VW2 A;  4X6K A;  2VW1 A;  2W20 A;  3CYE A;  1V0F A;  4QN5 A;  4CPN A;  4H53 A;  4WA3 A;  1IVF A;  4B7M A;  2QWB A;  1S0J A;  2BER A;  4XJU A;  4XMI A;  4FOV A;  4I00 A;  1INY A;  2QWG A;  2QWK A;  2F26 A;  4FJ6 A;  3B69 A;  2AH2 A;  3O9J A;  5HUG A;  1MS5 A;  4HZX A;  4GDJ A;  5B2D A;  1W8N A;  4YW2 A;  2HTY A;  2XZK A;  4GZW A;  2QWI A;  3TI4 A;  1NCC N;  1A14 N;  3D12 A;  1USX A;  2B8H A;  2W38 A;  1E8T A;  4MZE A;  4K1H A;  1IVD A;  1W8O A;  1EUT A;  3H71 A;  2CML A;  3K37 A;  1NNA A;  2SLI A;  3TIB A;  1V0Z A;  4X49 A;  4GZS A;  2X9M A;  4YZ4 A;  4HZZ A;  4FQ4 A;  4MC7 A;  3ALX A;  4MWY A;  2HTQ A;  2XCY A;  4MJV A;  2QWE A;  4FOW A;  4XJA A;  1KIT A;  3T1E A;  2A75 A;  1IVC A;  4GZQ A;  4GZP A;  1DIM A;  4KS2 A;  4X4A A;  2F12 A;  1N1V A;  4MWU A;  1S0I A;  5F9T A;  1MS0 A;  4XJ8 A;  4GZX A;  2VK5 A;  1NN2 A;  5HUM A;  4XOG A;  1NSB A;  4J9T A;  1E8U A;  4MJU A;  4NC5 A;  4XJR A;  4QN6 A;  5HUN A;  4KS4 A;  2F0Z A;  1A4Q A;  4WEF A;  2QWA A;  4CPO A; 
#chains in the Genus database with same CATH topology
 1W21 A;  2HU0 A;  1IVB A;  4HIZ A;  4ZY3 A;  1EUR A;  4K1J A;  5FNT A;  1N7D A;  4GN8 A;  4YW1 A;  1MS4 A;  2BAT A;  1SLL A;  4MWW A;  4FPO B;  1POO A;  2RKC A;  1L7G A;  2IVZ A;  2VK7 A;  4JF7 A;  1Q7F A;  1NMA N;  2BZD A;  2YA7 A;  3SOV A;  1NCB N;  3WDZ A;  1EUS A;  3TI3 A;  2IAO A;  1SUU A;  2HT7 A;  3O9K A;  2IAU A;  1V2I A;  3G4H A;  4GB1 A;  1QBI A;  2GHS A;  2IAT A;  3INB A;  2VWD A;  2OJH A;  1S18 A;  4HZY A;  3ZGD A;  1MZ5 A;  5EO8 A;  5GX2 A;  1MS8 A;  1Z4Z A;  1SLI A;  4FVK A;  1ZGK A;  1B9T A;  1F8D A;  4GZT A;  5M1Z A;  1C9U A;  1E8V A;  4C1Y B;  4FP3 A;  2F27 A;  2FP8 A;  4FPJ A;  4HHQ A;  1MS3 A;  1VCU A;  2IAX A;  3A71 A;  4M4V A;  4Q6K A;  1MS1 A;  2F24 A;  4K1K A;  3K38 A;  3IAX A;  1INV A;  3CL2 A;  4XJZ A;  1N1Y A;  4FZH A;  2F11 A;  5JYY A;  5GX3 A;  3TC9 A;  2W8B B;  3V64 C;  4FPH A;  1V3D A;  1MS9 A;  1V0E A;  4FP2 A;  1NMB N;  2H2N A;  2JKB A;  2AEQ A;  3K36 A;  4O5T A;  4YY8 A;  4GZO A;  1XOG A;  2GVX A;  2VSM A;  3BYC A;  4MWQ A;  1Z4W A;  1NSC A;  4K1I A;  4QN7 A;  1QLG A;  4H52 A;  1INX A;  4QN3 A;  1INF A;  2XZI A;  5B2C A;  2QWC A;  5FNQ A;  4IFN X;  4YW4 A;  3NN9 A;  3GVJ A;  5FNU A;  5HX0 A;  4MWJ A;  3OPZ A;  2SIM A;  1XOE A;  2ZZK A;  3JU4 A;  4FPK A;  4NCS A;  4B7N A;  2W5N A;  2YA6 A;  2VAQ A;  3WN7 A;  5GX1 A;  1N6E A;  1MWE A;  4FPY A;  4HZW A;  4R40 A;  2DG0 A;  3FVZ A;  2F25 A;  2VSK A;  1WCQ A;  1B9V A;  4GEZ A;  4XIO A;  3GVK A;  4ASC A;  3A72 A;  4XMA A;  2VVZ A;  1SO7 A;  2YA4 A;  4YZ3 A;  4L7B A;  4KS3 A;  2ZWA A;  1WP5 A;  1RWL A;  4MWV A;  1IVE A;  4M4N A;  2XZJ A;  3TI6 A;  3A9H A;  2YA5 A;  1INW A;  1ING A;  1F8E A;  4GNB A;  1NSD A;  4CPZ A;  2HQS A;  7NN9 A;  3SOB B;  4YZ5 A;  4XYX A;  4FPC A;  3WWA A;  4GDI A;  4B7R A;  5FNS A;  1EUU A;  5FZN A;  4NN9 A;  4AGT A;  3K39 A;  4XHB A;  3S2K A;  4D8S A;  2C4L A;  3TIC A;  1BJI A;  4MWL A;  1F8C A;  3ZGC A;  4GJT A;  1NMC A;  4CPM A;  4MWR A;  3G4E A;  3BEQ A;  4YW5 A;  1W1X A;  3TIA A;  2DSO A;  3SIL A;  4AGI A;  2QWH A;  4CPL A;  1WCS A;  3TI8 A;  3NO0 A;  4QN4 A;  1N1S A;  3B7E A;  3WW9 A;  3A9G A;  4XJW A;  2F13 A;  3Q6K A;  2HT5 A;  2QWF A;  3SAL A;  4B7Q A;  3V1S A;  4KS1 A;  2QE8 A;  1S1D A;  2YA8 A;  4CH9 A;  1IJQ A;  2DG1 A;  1VCJ A;  4FPL A;  4IYG A;  1NCD N;  2YDP A;  2GVV A;  4FPE A;  2HTV A;  5F72 C;  3DR2 A;  2IAQ A;  2AGS A;  4IFL X;  4FOY A;  4YZ2 A;  2F28 A;  4GNC A;  4GN9 A;  4XJQ A;  1X2J A;  1N6F A;  3PJQ A;  1Z4Y A;  2W5O A;  1Z4X A;  3LI4 A;  2AEP A;  2WOZ A;  3D11 A;  2DYH A;  2VW0 A;  1V3C A;  3FW0 A;  2IAP A;  4HZV A;  2GVW A;  1NNB A;  5FZJ A;  2HT8 A;  1ZI0 A;  4DGR A;  1INH A;  4G3N A;  1MR5 A;  2QWJ A;  4WA4 A;  4FOQ A;  3H6J A;  4UF7 A;  1E1A A;  4N1B A;  5HUK A;  1Z50 A;  2ZB5 A;  1A4G A;  1NNC A;  4M4U A;  2HU4 A;  2F29 A;  4FPF A;  4M3M A;  3SAN A;  4L7C A;  1CVM A;  3AMR A;  2C4A A;  2YDT A;  4X47 A;  4QNP A;  4B7J A;  1CRZ A;  4YW3 A;  3HLI A;  6NN9 A;  1V3B A;  3K3A A;  1N1T A;  2FLU X;  4MX0 A;  2VK6 A;  3W09 A;  3CL0 A;  4C1Y A;  4ZGC A;  1NCA N;  2POO A;  4KS5 A;  4IN4 A;  4XIK A;  1IVG A;  1Z4V A;  2HTU A;  3O4P A;  5GX4 A;  4MWX A;  4GNA A;  2VPJ A;  2QWD A;  1B9S A;  2FHR A;  2HTW A;  3S94 A;  4D52 C;  2SIL A;  3TI5 A;  4Q1U A;  4HHO A;  1U6D X;  3GVL A;  2GVU A;  1K32 A;  1USR A;  3VNH A;  3H73 A;  2XN4 A;  4XE9 A;  1MZ6 A;  4XHX A;  3CKZ A;  4FPG A;  4MZA A;  3KGG A;  2W8B A;  2ZB6 A;  4O5S A;  4PWZ A;  1F8B A;  2FPB A;  4XMB A;  4XIL A;  2HTR A;  1W0O A;  2IAV A;  2FP9 A;  3S8Z A;  4ZLR A;  1W0P A;  2F10 A;  5NN9 A;  3ALW A;  4SLI A;  1W20 A;  2H2U A;  4WA5 A;  2Z32 A;  1L7F A;  3DAS A;  1DIL A;  1L7H A;  4CPY A;  4K3Y A;  4BBW A;  4WEG A;  4XJ9 A;  4IFJ A;  3NSS A;  1V3E A;  4YZ1 A;  1SNT A;  4D52 B;  3SOQ A;  3H72 A;  2BF6 A;  4D4U A;  1H6L A;  3SLI A;  2VW2 A;  4X6K A;  2VW1 A;  5D9B A;  2W20 A;  3CYE A;  1V0F A;  4QN5 A;  4CPN A;  4H53 A;  4WA3 A;  1IVF A;  5EX7 A;  5FWW A;  1X2R A;  3VNG A;  4B7M A;  3LI5 A;  2QWB A;  1S0J A;  2BER A;  3V65 B;  1CQ1 A;  4XJU A;  4XMI A;  4FOV A;  4I00 A;  1INY A;  4JML A;  2QWG A;  2IAR A;  2QWK A;  4CSD A;  5D9C A;  2F26 A;  4FJ6 A;  3B69 A;  2AH2 A;  3O9J A;  1V04 A;  4IMB A;  4AH4 A;  5HUG A;  3HRP A;  1MS5 A;  4HZX A;  4GDJ A;  5B2D A;  3LI3 A;  1W8N A;  4L7D A;  4YW2 A;  2HTY A;  4UOU A;  3E5Z A;  2XZK A;  4GZW A;  3SRE A;  2QWI A;  3TI4 A;  1NCC N;  1A14 N;  3Q6T A;  3D12 A;  1N6D A;  3HLH A;  1PJX A;  4D52 A;  1USX A;  2B8H A;  2W38 A;  1E8T A;  2P4O A;  4MZE A;  5D9D A;  1IUC A;  4K1H A;  1IVD A;  1W8O A;  1EUT A;  4AHA A;  3H71 A;  2ISM A;  2CML A;  3K37 A;  1NNA A;  2SLI A;  3TIB A;  5GTQ A;  1V0Z A;  3KYA A;  3U0S A;  4X49 A;  5H47 A;  4GZS A;  3L6V A;  2X9M A;  3UC1 A;  1RWI A;  4YZ4 A;  4IQK A;  3SRG A;  4HZZ A;  2IAW A;  3Q6P A;  4FQ4 A;  3II7 A;  4GN7 A;  4MC7 A;  3ALX A;  4MWY A;  2HTQ A;  2XCY A;  4MJV A;  2QWE A;  4FOW A;  1NPE A;  4XJA A;  1KIT A;  3T1E A;  2A75 A;  1IVC A;  4GZQ A;  3AMS A;  1IUB A;  4GZP A;  1DIM A;  4KS2 A;  3P5B L;  4X4A A;  2F12 A;  4HW6 A;  1N1V A;  4MWU A;  1S0I A;  5F9T A;  1MS0 A;  2FPC A;  4XJ8 A;  5CGJ A;  4GZX A;  2VK5 A;  1NN2 A;  1CRU A;  5FNR A;  4A0P A;  3I1C A;  2G8S A;  5HUM A;  4XOG A;  1NSB A;  4J9T A;  1E8U A;  4MJU A;  1C5K A;  4NC5 A;  4XJR A;  4QN6 A;  2ZW9 A;  1OFZ A;  5HUN A;  4KS4 A;  2F0Z A;  2V91 A;  1A4Q A;  4DG6 A;  4CHB A;  3ADE A;  4WEF A;  3S8V A;  2IAS A;  2QWA A;  5EO7 A;  5GX5 A;  4CPO A; 
#chains in the Genus database with same CATH homology
 1W21 A;  2HU0 A;  1IVB A;  4HIZ A;  1EUR A;  4K1J A;  4YW1 A;  1MS4 A;  2BAT A;  1SLL A;  4MWW A;  4FPO B;  2RKC A;  1L7G A;  2VK7 A;  4JF7 A;  1NMA N;  2BZD A;  2YA7 A;  1NCB N;  1EUS A;  3TI3 A;  3O9K A;  2HT7 A;  1V2I A;  4GB1 A;  3INB A;  2VWD A;  1S18 A;  4HZY A;  1MZ5 A;  1MS8 A;  1Z4Z A;  1SLI A;  4FVK A;  1B9T A;  1F8D A;  4GZT A;  5M1Z A;  1E8V A;  4FP3 A;  2F27 A;  4FPJ A;  1MS3 A;  1VCU A;  4M4V A;  3A71 A;  4Q6K A;  1MS1 A;  2F24 A;  4K1K A;  3K38 A;  1INV A;  3CL2 A;  4XJZ A;  1N1Y A;  4FZH A;  2F11 A;  5JYY A;  4FPH A;  1V3D A;  1MS9 A;  1V0E A;  4FP2 A;  1NMB N;  2H2N A;  2JKB A;  2AEQ A;  3K36 A;  4GZO A;  1XOG A;  2VSM A;  4MWQ A;  1Z4W A;  1NSC A;  4K1I A;  4QN7 A;  4H52 A;  1INX A;  4QN3 A;  1INF A;  2XZI A;  5B2C A;  2QWC A;  4YW4 A;  3NN9 A;  3GVJ A;  5HX0 A;  4MWJ A;  3OPZ A;  2SIM A;  1XOE A;  3JU4 A;  4FPK A;  4NCS A;  4B7N A;  2W5N A;  2YA6 A;  4HZW A;  4FPY A;  1MWE A;  2F25 A;  2VSK A;  1WCQ A;  1B9V A;  4GEZ A;  4XIO A;  3GVK A;  3A72 A;  4XMA A;  2VVZ A;  1SO7 A;  2YA4 A;  4YZ3 A;  4KS3 A;  4MWV A;  1IVE A;  4M4N A;  2XZJ A;  3TI6 A;  2YA5 A;  1INW A;  1ING A;  1F8E A;  1NSD A;  4CPZ A;  7NN9 A;  4YZ5 A;  4XYX A;  4FPC A;  4GDI A;  4B7R A;  1EUU A;  4NN9 A;  3K39 A;  4XHB A;  4D8S A;  2C4L A;  3TIC A;  1BJI A;  4MWL A;  1F8C A;  4GJT A;  1NMC A;  4CPM A;  4MWR A;  3BEQ A;  4YW5 A;  1W1X A;  3TIA A;  3SIL A;  2QWH A;  4CPL A;  1WCS A;  3TI8 A;  4QN4 A;  1N1S A;  3B7E A;  4XJW A;  2F13 A;  2HT5 A;  2QWF A;  3SAL A;  4B7Q A;  4KS1 A;  1S1D A;  2YA8 A;  1VCJ A;  4FPL A;  1NCD N;  2YDP A;  4FPE A;  2HTV A;  2AGS A;  4FOY A;  4YZ2 A;  2F28 A;  4XJQ A;  3PJQ A;  1Z4Y A;  2W5O A;  1Z4X A;  2AEP A;  3D11 A;  2VW0 A;  1V3C A;  4HZV A;  1NNB A;  2HT8 A;  4DGR A;  1INH A;  1MR5 A;  2QWJ A;  4WA4 A;  4FOQ A;  3H6J A;  4UF7 A;  5HUK A;  1Z50 A;  2ZB5 A;  1A4G A;  1NNC A;  4M4U A;  2HU4 A;  2F29 A;  4FPF A;  4M3M A;  3SAN A;  2C4A A;  2YDT A;  4X47 A;  4QNP A;  4B7J A;  4YW3 A;  6NN9 A;  1V3B A;  3K3A A;  1N1T A;  4MX0 A;  2VK6 A;  3W09 A;  3CL0 A;  1NCA N;  4KS5 A;  4XIK A;  1IVG A;  1Z4V A;  2HTU A;  4MWX A;  2QWD A;  1B9S A;  2FHR A;  2HTW A;  2SIL A;  3TI5 A;  3GVL A;  1USR A;  3H73 A;  4XE9 A;  1MZ6 A;  4XHX A;  3CKZ A;  4FPG A;  4MZA A;  2ZB6 A;  1F8B A;  4XIL A;  2HTR A;  1W0O A;  1W0P A;  2F10 A;  5NN9 A;  3ALW A;  4SLI A;  1W20 A;  2H2U A;  4WA5 A;  1L7F A;  1DIL A;  1L7H A;  4CPY A;  4K3Y A;  4BBW A;  4WEG A;  4XJ9 A;  3NSS A;  1V3E A;  4YZ1 A;  1SNT A;  3H72 A;  2BF6 A;  3SLI A;  2VW2 A;  4X6K A;  2VW1 A;  2W20 A;  3CYE A;  1V0F A;  4QN5 A;  4CPN A;  4H53 A;  4WA3 A;  1IVF A;  4B7M A;  2QWB A;  1S0J A;  2BER A;  4XJU A;  4XMI A;  4FOV A;  4I00 A;  1INY A;  2QWG A;  2QWK A;  2F26 A;  4FJ6 A;  3B69 A;  2AH2 A;  3O9J A;  5HUG A;  1MS5 A;  4HZX A;  4GDJ A;  5B2D A;  1W8N A;  4YW2 A;  2HTY A;  2XZK A;  4GZW A;  2QWI A;  3TI4 A;  1NCC N;  1A14 N;  3D12 A;  1USX A;  2B8H A;  2W38 A;  1E8T A;  4MZE A;  4K1H A;  1IVD A;  1W8O A;  1EUT A;  3H71 A;  2CML A;  3K37 A;  1NNA A;  2SLI A;  3TIB A;  1V0Z A;  4X49 A;  4GZS A;  2X9M A;  4YZ4 A;  4HZZ A;  4FQ4 A;  4MC7 A;  3ALX A;  4MWY A;  2HTQ A;  2XCY A;  4MJV A;  2QWE A;  4FOW A;  4XJA A;  1KIT A;  3T1E A;  2A75 A;  1IVC A;  4GZQ A;  4GZP A;  1DIM A;  4KS2 A;  4X4A A;  2F12 A;  1N1V A;  4MWU A;  1S0I A;  5F9T A;  1MS0 A;  4XJ8 A;  4GZX A;  2VK5 A;  1NN2 A;  5HUM A;  4XOG A;  1NSB A;  4J9T A;  1E8U A;  4MJU A;  4NC5 A;  4XJR A;  4QN6 A;  5HUN A;  4KS4 A;  2F0Z A;  1A4Q A;  4WEF A;  2QWA A;  4CPO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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