1WP5A

Crystal structure of the c-terminal domain of dna topoisomerase iv
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
323
structure length
323
Chain Sequence
MVASEDVIVTVTKDGYVKRTSLRSYAASNGQDFAMKDTDRLLAMLEMNTKDVLLLFTNKGNYLYCPVHELPDIRWKDLGQHIANIIPIDRDEEIIKAIPINDFELNGYFLFVTRNGMVKKTELKHYKAQRYSKPLTGINLKNDDQVVDVHLTDGMNELFLVTHNGYALWFDESEVSIVGVRAAGVKGMNLKEGDYIVSGQLITSKDESIVVATQRGAVKKMKLTEFEKATRAKRGVVILRELKANPHRISGFVVAQDSDTIYLQTEKSFIETIKVGDIRFSDRYSNGSFVLDEEENGRVISVWKVEAEDKTEKLAAALEHHHH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the topoisomerase IV C-terminal domain: a broken beta-propeller implies a role as geometry facilitator in catalysis
pubmed doi rcsb
molecule tags Isomerase
source organism Geobacillus stearothermophilus
molecule keywords topoisomerase IV
total genus 82
structure length 323
sequence length 323
ec nomenclature ec 5.99.1.-:
pdb deposition date 2004-08-30
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.90 Mainly Beta 6 Propeller Neuraminidase DNA gyrase/topoisomerase IV, subunit A, C-terminal 1wp5A00
1SUUA 3NO0A 3L6VA 4G3NA 3UC1A 1ZI0A 1WP5A
chains in the Genus database with same CATH superfamily
4D4UA 1F8DA 2YDTA 1QBIA 3DR2A 4WA4A 4H52A 2DG0A 4YZ5A 4HZYA 4MWVA 4I00A 4XJWA 1NCCN 2IARA 3WW9A 1SUUA 4IFJA 2QWBA 4XJZA 2IASA 2IAQA 1K32A 1E8TA 3H73A 4L7BA 1EUTA 4FPYA 4AH4A 1IJQA 1MS1A 2RKCA 4SLIA 4K1KA 3II7A 4NC5A 4XILA 5B2DA 4HIZA 4IN4A 5H47A 1NMCA 3HRPA 3HLIA 2F28A 2GVXA 3PJQA 4FOWA 5M1ZA 3A72A 3Q6KA 4M4NA 1NNAA 3SOBB 4KS3A 4NCSA 4CPOA 4D8SA 3P5BL 2G8SA 5D9DA 3S8ZA 4QN4A 1V2IA 1Z4WA 3GVLA 3HLHA 4D52A 1NSBA 5FNTA 4GZQA 1NSCA 4FPJA 2ZW9A 4GZWA 3FW0A 5HUGA 2HTWA 4ZY3A 4N1BA 2VAQA 3SOVA 1INYA 1KITA 1U6DX 1POOA 1S0IA 1RWIA 4C1YA 5F9TA 3B7EA 4CPNA 4J9TA 3SRGA 1NPEA 3TICA 4XHXA 4YZ4A 1IVBA 4FPHA 4HZZA 3O9KA 4CPLA 1W8OA 4XJ9A 4IFLX 3O4PA 1SLIA 1A14N 1NMAN 2XZKA 6NN9A 3TI5A 3G4EA 4HZVA 4GDIA 3ALXA 3O9JA 4K1JA 2X9MA 5GX4A 1MS9A 4FPEA 4YZ3A 2W20A 4CPYA 1V04A 1IUCA 2QWAA 2W5NA 1Z50A 3V1SA 3JU4A 4GN8A 5HUNA 3S2KA 2F27A 3GVJA 2YA5A 3CYEA 1ZI0A 4FZHA 1X2JA 4JF7A 3CL2A 4M3MA 3K37A 4D52B 2F24A 4HHQA 4FPCA 5FWWA 4AHAA 4UF7A 2FPBA 1EUUA 4MJVA 2IAUA 5FNUA 2POOA 2FHRA 3A9HA 3S8VA 4C1YB 4JMLA 2HTUA 5GTQA 2F10A 2AEPA 4GEZA 2Z32A 4CPMA 4PWZA 5NN9A 2XN4A 2V91A 1B9SA 4K3YA 2HTVA 1MZ5A 4MWRA 4YZ1A 4FPLA 1IVGA 2IAWA 5EO8A 1MWEA 1IVCA 1CQ1A 1MS4A 2QWIA 3Q6PA 5GX2A 1NCBN 4KS4A 3SOQA 4B7NA 1USRA 1INVA 2W5OA 3KYAA 4FJ6A 2HT8A 3TI8A 4GZOA 1N1VA 1NNCA 1QLGA 2HQSA 4YW4A 2F13A 5D9CA 4K1IA 5FNQA 1V0ZA 2BATA 2ZZKA 4XIKA 1VCJA 1SNTA 1IVFA 4KS2A 4CPZA 2HT7A 2ZB6A 4XE9A 2GVWA 3ZGCA 1A4GA 1W1XA 4YW1A 4GZPA 2C4LA 1MS0A 2SILA 3K39A 1W0OA 4FP2A 1V3BA 2H2UA 4X4AA 3U0SA 2VSMA 1F8BA 1N7DA 2IAXA 2C4AA 3SLIA 2ISMA 2H2NA 4FOVA 4MC7A 3L6VA 2DYHA 2VSKA 4FPKA 1INXA 4MZAA 4IQKA 5FZNA 3SALA 2A75A 2P4OA 3S94A 2F0ZA 4WEFA 4YW5A 5GX3A 2QWEA 4HZXA 3ZGDA 1C9UA 1W8NA 2VW2A 3GVKA 4M4UA 5FNRA 3SILA 1Q7FA 2SLIA 4YW2A 7NN9A 3VNHA 1N1SA 4BBWA 1V3DA 2YDPA 4X49A 4A0PA 2B8HA 5HUKA 1DILA 2QE8A 4YW3A 2HU0A 2IAOA 4AGIA 2QWKA 2YA4A 4UOUA 1IVEA 2VK7A 1N6FA 1W21A 3K36A 4GZSA 3SANA 1S0JA 2XZIA 1USXA 4GDJA 2BZDA 5EO7A 3NN9A 3TI3A 1E8UA 5EX7A 2QWHA 3WDZA 2AEQA 2QWJA 3AMRA 2VK5A 4FPFA 4FVKA 1C5KA 3NO0A 1IVDA 1W20A 3D12A 2VW0A 5CGJA 2GHSA 4MWUA 1B9TA 1W0PA 2IAVA 3KGGA 3H72A 5HX0A 3B69A 4FPGA 3ALWA 4CHBA 4B7MA 1EURA 4GNBA 4GN9A 4O5SA 4XMIA 1INWA 1NSDA 3CL0A 5D9BA 4L7DA 4Q1UA 1XOEA 4DG6A 3H71A 4QN6A 1MZ6A 4GZTA 1CVMA 4QN3A 4XJUA 4B7QA 2F29A 2DG1A 4XYXA 2ZWAA 2HTQA 3E5ZA 2JKBA 2YA6A 1Z4VA 1OFZA 1EUSA 2W8BB 1E8VA 2W38A 4IFNX 1S1DA 5JYYA 2CMLA 1NCDN 2BF6A 3IAXA 2F12A 4KS1A 2IATA 4MWLA 4D52C 4MJUA 3V64C 1INHA 3AMSA 5GX1A 2VVZA 1NN2A 4WEGA 1B9VA 3H6JA 1ZGKA 3BEQA 4GZXA 3WN7A 1Z4YA 2HT5A 4FQ4A 4IYGA 3D11A 1WCSA 2XCYA 1N1TA 3VNGA 4DGRA 3V65B 2DSOA 4L7CA 4H53A 4K1HA 5FNSA 4CSDA 1A4QA 4HW6A 1VCUA 2F25A 4MX0A 2VW1A 3A9GA 2FLUX 2GVUA 5HUMA 4XOGA 2QWCA 4M4VA 1X2RA 4WA5A 4WA3A 2AGSA 4ASCA 3INBA 2OJHA 1N6EA 2HTRA 2QWGA 3FVZA 4YY8A 4ZLRA 3K38A 1IUBA 4XJ8A 2FP9A 1INGA 2VWDA 2QWFA 4MZEA 3ADEA 1L7FA 1V0FA 4ZGCA 1MS3A 4XJAA 2BERA 1NNBA 2VK6A 2AH2A 3UC1A 4B7JA 2W8BA 3LI4A 1MR5A 3TI6A 2FP8A 2IAPA 1INFA 3BYCA 4MWWA 4HHOA 1DIMA 4XMAA 5FZJA 1MS5A 2YA7A 1L7GA 3NSSA 3CKZA 1RWLA 1WCQA 1V0EA 5B2CA 5GX5A 2HTYA 2F26A 1S18A 3W09A 1H6LA 4AGTA 4XIOA 2SIMA 4QN7A 4XJQA 2GVVA 4XJRA 4MWJA 2QWDA 1CRZA 3K3AA 3A71A 4X47A 4NN9A 4QNPA 4FOYA 1NMBN 1Z4XA 3TI4A 1N6DA 3LI5A 2WOZA 3I1CA 4FOQA 5F72C 3WWAA 1SLLA 4CH9A 4GNAA 1L7HA 4G3NA 4FPOB 4YZ2A 2VPJA 4Q6KA 1V3CA 1F8CA 4MWXA 1NCAN 1CRUA 4XMBA 2YA8A 2XZJA 1MS8A 1Z4ZA 4IMBA 3Q6TA 2HU4A 1N1YA 1E1AA 2IVZA 4QN5A 3T1EA 4GN7A 2FPCA 4MWYA 3DASA 2F11A 1XOGA 4KS5A 4FP3A 1BJIA 3SREA 3G4HA 1PJXA 3TC9A 3TIBA 4XHBA 1SO7A 4B7RA 3OPZA 4GB1A 4R40A 4GNCA 1WP5A 3LI3A 4X6KA 1V3EA 4O5TA 4HZWA 1F8EA 3TIAA 4GJTA 2ZB5A 4MWQA
chains in the Genus database with same CATH topology
1SUUA 3NO0A 3L6VA 4G3NA 3UC1A 1ZI0A 1WP5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SUU A;  3NO0 A;  3L6V A;  4G3N A;  3UC1 A;  1ZI0 A;  1WP5 A; 
#chains in the Genus database with same CATH topology
 4D4U A;  1F8D A;  2YDT A;  1QBI A;  3DR2 A;  4WA4 A;  4H52 A;  2DG0 A;  4YZ5 A;  4HZY A;  4MWV A;  4I00 A;  4XJW A;  1NCC N;  2IAR A;  3WW9 A;  1SUU A;  4IFJ A;  2QWB A;  4XJZ A;  2IAS A;  2IAQ A;  1K32 A;  1E8T A;  3H73 A;  4L7B A;  1EUT A;  4FPY A;  4AH4 A;  1IJQ A;  1MS1 A;  2RKC A;  4SLI A;  4K1K A;  3II7 A;  4NC5 A;  4XIL A;  5B2D A;  4HIZ A;  4IN4 A;  5H47 A;  1NMC A;  3HRP A;  3HLI A;  2F28 A;  2GVX A;  3PJQ A;  4FOW A;  5M1Z A;  3A72 A;  3Q6K A;  4M4N A;  1NNA A;  3SOB B;  4KS3 A;  4NCS A;  4CPO A;  4D8S A;  3P5B L;  2G8S A;  5D9D A;  3S8Z A;  4QN4 A;  1V2I A;  1Z4W A;  3GVL A;  3HLH A;  4D52 A;  1NSB A;  5FNT A;  4GZQ A;  1NSC A;  4FPJ A;  2ZW9 A;  4GZW A;  3FW0 A;  5HUG A;  2HTW A;  4ZY3 A;  4N1B A;  2VAQ A;  3SOV A;  1INY A;  1KIT A;  1U6D X;  1POO A;  1S0I A;  1RWI A;  4C1Y A;  5F9T A;  3B7E A;  4CPN A;  4J9T A;  3SRG A;  1NPE A;  3TIC A;  4XHX A;  4YZ4 A;  1IVB A;  4FPH A;  4HZZ A;  3O9K A;  4CPL A;  1W8O A;  4XJ9 A;  4IFL X;  3O4P A;  1SLI A;  1A14 N;  1NMA N;  2XZK A;  6NN9 A;  3TI5 A;  3G4E A;  4HZV A;  4GDI A;  3ALX A;  3O9J A;  4K1J A;  2X9M A;  5GX4 A;  1MS9 A;  4FPE A;  4YZ3 A;  2W20 A;  4CPY A;  1V04 A;  1IUC A;  2QWA A;  2W5N A;  1Z50 A;  3V1S A;  3JU4 A;  4GN8 A;  5HUN A;  3S2K A;  2F27 A;  3GVJ A;  2YA5 A;  3CYE A;  1ZI0 A;  4FZH A;  1X2J A;  4JF7 A;  3CL2 A;  4M3M A;  3K37 A;  4D52 B;  2F24 A;  4HHQ A;  4FPC A;  5FWW A;  4AHA A;  4UF7 A;  2FPB A;  1EUU A;  4MJV A;  2IAU A;  5FNU A;  2POO A;  2FHR A;  3A9H A;  3S8V A;  4C1Y B;  4JML A;  2HTU A;  5GTQ A;  2F10 A;  2AEP A;  4GEZ A;  2Z32 A;  4CPM A;  4PWZ A;  5NN9 A;  2XN4 A;  2V91 A;  1B9S A;  4K3Y A;  2HTV A;  1MZ5 A;  4MWR A;  4YZ1 A;  4FPL A;  1IVG A;  2IAW A;  5EO8 A;  1MWE A;  1IVC A;  1CQ1 A;  1MS4 A;  2QWI A;  3Q6P A;  5GX2 A;  1NCB N;  4KS4 A;  3SOQ A;  4B7N A;  1USR A;  1INV A;  2W5O A;  3KYA A;  4FJ6 A;  2HT8 A;  3TI8 A;  4GZO A;  1N1V A;  1NNC A;  1QLG A;  2HQS A;  4YW4 A;  2F13 A;  5D9C A;  4K1I A;  5FNQ A;  1V0Z A;  2BAT A;  2ZZK A;  4XIK A;  1VCJ A;  1SNT A;  1IVF A;  4KS2 A;  4CPZ A;  2HT7 A;  2ZB6 A;  4XE9 A;  2GVW A;  3ZGC A;  1A4G A;  1W1X A;  4YW1 A;  4GZP A;  2C4L A;  1MS0 A;  2SIL A;  3K39 A;  1W0O A;  4FP2 A;  1V3B A;  2H2U A;  4X4A A;  3U0S A;  2VSM A;  1F8B A;  1N7D A;  2IAX A;  2C4A A;  3SLI A;  2ISM A;  2H2N A;  4FOV A;  4MC7 A;  3L6V A;  2DYH A;  2VSK A;  4FPK A;  1INX A;  4MZA A;  4IQK A;  5FZN A;  3SAL A;  2A75 A;  2P4O A;  3S94 A;  2F0Z A;  4WEF A;  4YW5 A;  5GX3 A;  2QWE A;  4HZX A;  3ZGD A;  1C9U A;  1W8N A;  2VW2 A;  3GVK A;  4M4U A;  5FNR A;  3SIL A;  1Q7F A;  2SLI A;  4YW2 A;  7NN9 A;  3VNH A;  1N1S A;  4BBW A;  1V3D A;  2YDP A;  4X49 A;  4A0P A;  2B8H A;  5HUK A;  1DIL A;  2QE8 A;  4YW3 A;  2HU0 A;  2IAO A;  4AGI A;  2QWK A;  2YA4 A;  4UOU A;  1IVE A;  2VK7 A;  1N6F A;  1W21 A;  3K36 A;  4GZS A;  3SAN A;  1S0J A;  2XZI A;  1USX A;  4GDJ A;  2BZD A;  5EO7 A;  3NN9 A;  3TI3 A;  1E8U A;  5EX7 A;  2QWH A;  3WDZ A;  2AEQ A;  2QWJ A;  3AMR A;  2VK5 A;  4FPF A;  4FVK A;  1C5K A;  3NO0 A;  1IVD A;  1W20 A;  3D12 A;  2VW0 A;  5CGJ A;  2GHS A;  4MWU A;  1B9T A;  1W0P A;  2IAV A;  3KGG A;  3H72 A;  5HX0 A;  3B69 A;  4FPG A;  3ALW A;  4CHB A;  4B7M A;  1EUR A;  4GNB A;  4GN9 A;  4O5S A;  4XMI A;  1INW A;  1NSD A;  3CL0 A;  5D9B A;  4L7D A;  4Q1U A;  1XOE A;  4DG6 A;  3H71 A;  4QN6 A;  1MZ6 A;  4GZT A;  1CVM A;  4QN3 A;  4XJU A;  4B7Q A;  2F29 A;  2DG1 A;  4XYX A;  2ZWA A;  2HTQ A;  3E5Z A;  2JKB A;  2YA6 A;  1Z4V A;  1OFZ A;  1EUS A;  2W8B B;  1E8V A;  2W38 A;  4IFN X;  1S1D A;  5JYY A;  2CML A;  1NCD N;  2BF6 A;  3IAX A;  2F12 A;  4KS1 A;  2IAT A;  4MWL A;  4D52 C;  4MJU A;  3V64 C;  1INH A;  3AMS A;  5GX1 A;  2VVZ A;  1NN2 A;  4WEG A;  1B9V A;  3H6J A;  1ZGK A;  3BEQ A;  4GZX A;  3WN7 A;  1Z4Y A;  2HT5 A;  4FQ4 A;  4IYG A;  3D11 A;  1WCS A;  2XCY A;  1N1T A;  3VNG A;  4DGR A;  3V65 B;  2DSO A;  4L7C A;  4H53 A;  4K1H A;  5FNS A;  4CSD A;  1A4Q A;  4HW6 A;  1VCU A;  2F25 A;  4MX0 A;  2VW1 A;  3A9G A;  2FLU X;  2GVU A;  5HUM A;  4XOG A;  2QWC A;  4M4V A;  1X2R A;  4WA5 A;  4WA3 A;  2AGS A;  4ASC A;  3INB A;  2OJH A;  1N6E A;  2HTR A;  2QWG A;  3FVZ A;  4YY8 A;  4ZLR A;  3K38 A;  1IUB A;  4XJ8 A;  2FP9 A;  1ING A;  2VWD A;  2QWF A;  4MZE A;  3ADE A;  1L7F A;  1V0F A;  4ZGC A;  1MS3 A;  4XJA A;  2BER A;  1NNB A;  2VK6 A;  2AH2 A;  3UC1 A;  4B7J A;  2W8B A;  3LI4 A;  1MR5 A;  3TI6 A;  2FP8 A;  2IAP A;  1INF A;  3BYC A;  4MWW A;  4HHO A;  1DIM A;  4XMA A;  5FZJ A;  1MS5 A;  2YA7 A;  1L7G A;  3NSS A;  3CKZ A;  1RWL A;  1WCQ A;  1V0E A;  5B2C A;  5GX5 A;  2HTY A;  2F26 A;  1S18 A;  3W09 A;  1H6L A;  4AGT A;  4XIO A;  2SIM A;  4QN7 A;  4XJQ A;  2GVV A;  4XJR A;  4MWJ A;  2QWD A;  1CRZ A;  3K3A A;  3A71 A;  4X47 A;  4NN9 A;  4QNP A;  4FOY A;  1NMB N;  1Z4X A;  3TI4 A;  1N6D A;  3LI5 A;  2WOZ A;  3I1C A;  4FOQ A;  5F72 C;  3WWA A;  1SLL A;  4CH9 A;  4GNA A;  1L7H A;  4G3N A;  4FPO B;  4YZ2 A;  2VPJ A;  4Q6K A;  1V3C A;  1F8C A;  4MWX A;  1NCA N;  1CRU A;  4XMB A;  2YA8 A;  2XZJ A;  1MS8 A;  1Z4Z A;  4IMB A;  3Q6T A;  2HU4 A;  1N1Y A;  1E1A A;  2IVZ A;  4QN5 A;  3T1E A;  4GN7 A;  2FPC A;  4MWY A;  3DAS A;  2F11 A;  1XOG A;  4KS5 A;  4FP3 A;  1BJI A;  3SRE A;  3G4H A;  1PJX A;  3TC9 A;  3TIB A;  4XHB A;  1SO7 A;  4B7R A;  3OPZ A;  4GB1 A;  4R40 A;  4GNC A;  1WP5 A;  3LI3 A;  4X6K A;  1V3E A;  4O5T A;  4HZW A;  1F8E A;  3TIA A;  4GJT A;  2ZB5 A;  4MWQ A; 
#chains in the Genus database with same CATH homology
 1SUU A;  3NO0 A;  3L6V A;  4G3N A;  3UC1 A;  1ZI0 A;  1WP5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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