1ZGKA

1.35 angstrom structure of the kelch domain of keap1
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
288
structure length
288
Chain Sequence
PKVGRLIYTAGGYFRQSLSYLEAYNPSNGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Conserved solvent and side-chain interactions in the 1.35 Angstrom structure of the Kelch domain of Keap1.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Kelch-like ECH-associated protein 1
total genus 61
structure length 288
sequence length 288
ec nomenclature
pdb deposition date 2005-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 1zgkA00
5FNTA 2ZW9A 2Z32A 4IFNX 2WOZA 5FNSA 4IN4A 4IFLX 5FZNA 3WDZA 4IFJA 2ZZKA 1X2JA 4CHBA 4L7CA 4YY8A 4ZGCA 4L7DA 2XN4A 4ASCA 4L7BA 3II7A 4ZY3A 2ZWAA 3ZGCA 5CGJA 3VNGA 1ZGKA 4IQKA 3WN7A 1X2RA 4XMBA 3VNHA 3ZGDA 5F72C 5FZJA 2VPJA 5FNRA 4CH9A 5FNUA 3ADEA 4N1BA 2FLUX 5FNQA 1U6DX 2DYHA
chains in the Genus database with same CATH superfamily
4X49A 5FNTA 4B7MA 4XJWA 4CSDA 3H73A 3PJQA 5FNSA 4IFLX 1S0JA 4MWLA 4YZ2A 2F0ZA 1W8NA 4GN9A 1H6LA 5B2DA 2HTQA 4YW3A 4XE9A 1Q7FA 4MJUA 4AGTA 1Z4ZA 4GJTA 4H52A 4FOYA 1A4QA 4FPHA 4MWWA 3W09A 1EUSA 1DILA 1ZI0A 1N1YA 3SRGA 4DG6A 4HHQA 3WW9A 1INFA 2SILA 4B7RA 3H71A 4L7BA 3G4HA 1IVEA 2OJHA 2ZWAA 3S8VA 5GX2A 1V04A 2FPBA 4BBWA 1MZ6A 2QWBA 4XILA 1IVCA 4K3YA 3NO0A 2H2UA 3SOBB 4B7NA 3BEQA 3S94A 4AHAA 1W8OA 2VSKA 4PWZA 4XJQA 1C9UA 4FPYA 2B8HA 4GNBA 1L7HA 4MWUA 3SLIA 4UF7A 4IN4A 1CRUA 4UOUA 2YA4A 2QWGA 4NC5A 2QWCA 5D9BA 5EO7A 1SO7A 2FP8A 1USRA 2VW1A 4GZTA 4QN3A 1MS0A 3TI3A 4IQKA 1A4GA 2IATA 1INXA 4XJAA 3WWAA 2VPJA 4GDIA 2IASA 1F8BA 3SILA 1U6DX 5D9DA 1PJXA 1W21A 4C1YA 5HUMA 2DSOA 2GVWA 1IVBA 4IFJA 1INHA 4M4UA 4CPYA 1USXA 4FP2A 2IVZA 3D12A 4FQ4A 2GVVA 2FHRA 3D11A 3VNGA 4Q1UA 3O9KA 4M3MA 1F8DA 3GVKA 2C4AA 5JYYA 4FPJA 4YZ1A 2HT7A 4KS1A 2BF6A 1V3DA 3Q6PA 1NCDN 1WP5A 4D52C 2WOZA 1INYA 2QWHA 1IUCA 4GZPA 4MWQA 1N6FA 3AMRA 1SLIA 4ZY3A 1POOA 4HZVA 3V65B 3ZGCA 1V0FA 4FPGA 4CPNA 1NMAN 4CPMA 1N6EA 5GX1A 2C4LA 2XZIA 4FPKA 4CH9A 1MS1A 2VAQA 4YW4A 1CVMA 2IAQA 3BYCA 1B9TA 2F11A 4QN7A 4IFNX 1IVDA 1S0IA 2HU0A 4HZZA 4SLIA 2IAWA 5EO8A 5GX5A 4A0PA 1Z4WA 3HLIA 3TIBA 1X2JA 3A72A 2F24A 2F27A 4K1KA 2BERA 4HW6A 6NN9A 2IAPA 3A9HA 3TI8A 3V64C 5H47A 2BZDA 4FPOB 4MWRA 4QN5A 3P5BL 4K1IA 1E8TA 1N7DA 3SOVA 5F72C 1NMCA 4XIKA 1W0OA 3TI4A 5FNUA 1N1SA 4Q6KA 1DIMA 2DYHA 4MZEA 2YA5A 4FPLA 2FP9A 4H53A 1IJQA 1XOGA 3H72A 2VK5A 4FOVA 4YZ3A 2FPCA 3TC9A 4WA4A 4X6KA 3K38A 4FZHA 1INWA 2VVZA 4ASCA 4D8SA 2HTRA 2W5NA 3TI6A 3L6VA 2CMLA 1NCBN 2BATA 4M4VA 3LI3A 3DR2A 3HLHA 4XMBA 3ZGDA 2P4OA 2QWDA 5M1ZA 4X47A 2XZKA 1Z4VA 2QE8A 2ISMA 4YZ5A 3U0SA 2ZW9A 2VK6A 3B69A 4FP3A 2F13A 2V91A 1SUUA 1Z4XA 2A75A 5HX0A 4MWVA 4O5SA 3S2KA 1E1AA 5HUKA 2QWAA 1S18A 1NCCN 2QWFA 2HT5A 1N6DA 1V3BA 2SLIA 4MWYA 1MZ5A 2RKCA 1MS9A 2ZB6A 3Q6KA 2F10A 2AH2A 4D52B 4NCSA 3ALWA 3G4EA 3TIAA 1XOEA 1MS4A 4GDJA 4CPZA 4CHBA 1MS5A 4ZGCA 1B9VA 4MWXA 2HTWA 2G8SA 3SREA 3AMSA 1NNBA 3SALA 4IYGA 3CYEA 3IAXA 4NN9A 2XCYA 4HZXA 1X2RA 2VW0A 4XJZA 1W0PA 3GVLA 1NSCA 3FVZA 3UC1A 4B7JA 2F28A 2W8BB 4R40A 2ZB5A 2F29A 2JKBA 5FNQA 2QWJA 3O4PA 2IAUA 1NSBA 2HU4A 1F8EA 2W5OA 3JU4A 5HUGA 1QBIA 2XN4A 3K3AA 1OFZA 4ZLRA 1NSDA 4X4AA 5GTQA 4XOGA 3K37A 4YW2A 1INVA 5NN9A 3K39A 4QNPA 2IAOA 4HZYA 4WEFA 4XIOA 2AEPA 2GVUA 2F26A 1WCQA 4L7CA 2DG1A 1WCSA 3B7EA 1NNAA 4FVKA 3T1EA 2W20A 3V1SA 1Z4YA 1V0EA 4AH4A 3CL0A 1ZGKA 4GZXA 5D9CA 3WN7A 2HTUA 1EURA 3DASA 2SIMA 3TICA 3O9JA 5EX7A 3A71A 4KS3A 1IUBA 2VK7A 1C5KA 2X9MA 7NN9A 3FW0A 1NNCA 4QN6A 1INGA 2HQSA 4M4NA 5FZNA 1NCAN 3INBA 4XMIA 1MS8A 4AGIA 3II7A 1RWIA 4MC7A 3ALXA 4WA3A 4D52A 2YA7A 2DG0A 1RWLA 3KYAA 2QWIA 4KS5A 1E8VA 4GZQA 3S8ZA 3Q6TA 3ADEA 4MWJA 1W1XA 4HZWA 2IARA 1QLGA 2Z32A 4XJ8A 1N1VA 2XZJA 3NN9A 4O5TA 5B2CA 4FOWA 1K32A 2VWDA 2HT8A 4HIZA 4YW5A 1SLLA 3WDZA 4B7QA 1VCUA 2W8BA 1L7FA 3LI5A 3K36A 4WEGA 1CQ1A 1F8CA 4GN8A 5GX3A 2H2NA 1IVFA 3HRPA 5FNRA 4GZWA 4XJ9A 3E5ZA 4KS2A 3LI4A 2YA8A 4WA5A 2VW2A 3KGGA 1VCJA 1V0ZA 1SNTA 1S1DA 4IMBA 4GB1A 1EUUA 4GEZA 1V2IA 3OPZA 1MR5A 3A9GA 2VSMA 1MS3A 4MJVA 4QN4A 2YA6A 3GVJA 2POOA 2QWEA 3SANA 4CPLA 5GX4A 4FOQA 1KITA 1V3EA 4D4UA 4FPFA 2FLUX 1CRZA 4YW1A 2AEQA 1MWEA 3CKZA 1E8UA 4GN7A 2ZZKA 5FWWA 4MZAA 4G3NA 4L7DA 4XJUA 1A14N 4JF7A 2QWKA 2F12A 2IAVA 3I1CA 5CGJA 4K1JA 4YZ4A 4JMLA 4XYXA 3VNHA 4DGRA 3CL2A 1NMBN 1EUTA 4GZOA 3SOQA 4N1BA 4CPOA 1NN2A 1B9SA 2F25A 4K1HA 4GNAA 4XHBA 2IAXA 4YY8A 4FPCA 1W20A 4GZSA 4XHXA 4GNCA 1Z50A 4HHOA 4KS4A 4FJ6A 5F9TA 3TI5A 4C1YB 1NPEA 2W38A 4J9TA 2GVXA 2YDTA 2HTYA 4I00A 4MX0A 4XJRA 3NSSA 3H6JA 5HUNA 2AGSA 2GHSA 1BJIA 1N1TA 4FPEA 1IVGA 5FZJA 4XMAA 2HTVA 1L7GA 1V3CA 2YDPA
chains in the Genus database with same CATH topology
5FNTA 2ZW9A 2Z32A 4IFNX 2WOZA 5FNSA 4IN4A 4IFLX 5FZNA 3WDZA 4IFJA 2ZZKA 1X2JA 4CHBA 4L7CA 4YY8A 4ZGCA 4L7DA 2XN4A 4ASCA 4L7BA 3II7A 4ZY3A 2ZWAA 3ZGCA 5CGJA 3VNGA 1ZGKA 4IQKA 3WN7A 1X2RA 4XMBA 3VNHA 3ZGDA 5F72C 5FZJA 2VPJA 5FNRA 4CH9A 5FNUA 3ADEA 4N1BA 2FLUX 5FNQA 1U6DX 2DYHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5FNT A;  2ZW9 A;  2Z32 A;  4IFN X;  2WOZ A;  5FNS A;  4IN4 A;  4IFL X;  5FZN A;  3WDZ A;  4IFJ A;  2ZZK A;  1X2J A;  4CHB A;  4L7C A;  4YY8 A;  4ZGC A;  4L7D A;  2XN4 A;  4ASC A;  4L7B A;  3II7 A;  4ZY3 A;  2ZWA A;  3ZGC A;  5CGJ A;  3VNG A;  1ZGK A;  4IQK A;  3WN7 A;  1X2R A;  4XMB A;  3VNH A;  3ZGD A;  5F72 C;  5FZJ A;  2VPJ A;  5FNR A;  4CH9 A;  5FNU A;  3ADE A;  4N1B A;  2FLU X;  5FNQ A;  1U6D X;  2DYH A; 
#chains in the Genus database with same CATH topology
 4X49 A;  5FNT A;  4B7M A;  4XJW A;  4CSD A;  3H73 A;  3PJQ A;  5FNS A;  4IFL X;  1S0J A;  4MWL A;  4YZ2 A;  2F0Z A;  1W8N A;  4GN9 A;  1H6L A;  5B2D A;  2HTQ A;  4YW3 A;  4XE9 A;  1Q7F A;  4MJU A;  4AGT A;  1Z4Z A;  4GJT A;  4H52 A;  4FOY A;  1A4Q A;  4FPH A;  4MWW A;  3W09 A;  1EUS A;  1DIL A;  1ZI0 A;  1N1Y A;  3SRG A;  4DG6 A;  4HHQ A;  3WW9 A;  1INF A;  2SIL A;  4B7R A;  3H71 A;  4L7B A;  3G4H A;  1IVE A;  2OJH A;  2ZWA A;  3S8V A;  5GX2 A;  1V04 A;  2FPB A;  4BBW A;  1MZ6 A;  2QWB A;  4XIL A;  1IVC A;  4K3Y A;  3NO0 A;  2H2U A;  3SOB B;  4B7N A;  3BEQ A;  3S94 A;  4AHA A;  1W8O A;  2VSK A;  4PWZ A;  4XJQ A;  1C9U A;  4FPY A;  2B8H A;  4GNB A;  1L7H A;  4MWU A;  3SLI A;  4UF7 A;  4IN4 A;  1CRU A;  4UOU A;  2YA4 A;  2QWG A;  4NC5 A;  2QWC A;  5D9B A;  5EO7 A;  1SO7 A;  2FP8 A;  1USR A;  2VW1 A;  4GZT A;  4QN3 A;  1MS0 A;  3TI3 A;  4IQK A;  1A4G A;  2IAT A;  1INX A;  4XJA A;  3WWA A;  2VPJ A;  4GDI A;  2IAS A;  1F8B A;  3SIL A;  1U6D X;  5D9D A;  1PJX A;  1W21 A;  4C1Y A;  5HUM A;  2DSO A;  2GVW A;  1IVB A;  4IFJ A;  1INH A;  4M4U A;  4CPY A;  1USX A;  4FP2 A;  2IVZ A;  3D12 A;  4FQ4 A;  2GVV A;  2FHR A;  3D11 A;  3VNG A;  4Q1U A;  3O9K A;  4M3M A;  1F8D A;  3GVK A;  2C4A A;  5JYY A;  4FPJ A;  4YZ1 A;  2HT7 A;  4KS1 A;  2BF6 A;  1V3D A;  3Q6P A;  1NCD N;  1WP5 A;  4D52 C;  2WOZ A;  1INY A;  2QWH A;  1IUC A;  4GZP A;  4MWQ A;  1N6F A;  3AMR A;  1SLI A;  4ZY3 A;  1POO A;  4HZV A;  3V65 B;  3ZGC A;  1V0F A;  4FPG A;  4CPN A;  1NMA N;  4CPM A;  1N6E A;  5GX1 A;  2C4L A;  2XZI A;  4FPK A;  4CH9 A;  1MS1 A;  2VAQ A;  4YW4 A;  1CVM A;  2IAQ A;  3BYC A;  1B9T A;  2F11 A;  4QN7 A;  4IFN X;  1IVD A;  1S0I A;  2HU0 A;  4HZZ A;  4SLI A;  2IAW A;  5EO8 A;  5GX5 A;  4A0P A;  1Z4W A;  3HLI A;  3TIB A;  1X2J A;  3A72 A;  2F24 A;  2F27 A;  4K1K A;  2BER A;  4HW6 A;  6NN9 A;  2IAP A;  3A9H A;  3TI8 A;  3V64 C;  5H47 A;  2BZD A;  4FPO B;  4MWR A;  4QN5 A;  3P5B L;  4K1I A;  1E8T A;  1N7D A;  3SOV A;  5F72 C;  1NMC A;  4XIK A;  1W0O A;  3TI4 A;  5FNU A;  1N1S A;  4Q6K A;  1DIM A;  2DYH A;  4MZE A;  2YA5 A;  4FPL A;  2FP9 A;  4H53 A;  1IJQ A;  1XOG A;  3H72 A;  2VK5 A;  4FOV A;  4YZ3 A;  2FPC A;  3TC9 A;  4WA4 A;  4X6K A;  3K38 A;  4FZH A;  1INW A;  2VVZ A;  4ASC A;  4D8S A;  2HTR A;  2W5N A;  3TI6 A;  3L6V A;  2CML A;  1NCB N;  2BAT A;  4M4V A;  3LI3 A;  3DR2 A;  3HLH A;  4XMB A;  3ZGD A;  2P4O A;  2QWD A;  5M1Z A;  4X47 A;  2XZK A;  1Z4V A;  2QE8 A;  2ISM A;  4YZ5 A;  3U0S A;  2ZW9 A;  2VK6 A;  3B69 A;  4FP3 A;  2F13 A;  2V91 A;  1SUU A;  1Z4X A;  2A75 A;  5HX0 A;  4MWV A;  4O5S A;  3S2K A;  1E1A A;  5HUK A;  2QWA A;  1S18 A;  1NCC N;  2QWF A;  2HT5 A;  1N6D A;  1V3B A;  2SLI A;  4MWY A;  1MZ5 A;  2RKC A;  1MS9 A;  2ZB6 A;  3Q6K A;  2F10 A;  2AH2 A;  4D52 B;  4NCS A;  3ALW A;  3G4E A;  3TIA A;  1XOE A;  1MS4 A;  4GDJ A;  4CPZ A;  4CHB A;  1MS5 A;  4ZGC A;  1B9V A;  4MWX A;  2HTW A;  2G8S A;  3SRE A;  3AMS A;  1NNB A;  3SAL A;  4IYG A;  3CYE A;  3IAX A;  4NN9 A;  2XCY A;  4HZX A;  1X2R A;  2VW0 A;  4XJZ A;  1W0P A;  3GVL A;  1NSC A;  3FVZ A;  3UC1 A;  4B7J A;  2F28 A;  2W8B B;  4R40 A;  2ZB5 A;  2F29 A;  2JKB A;  5FNQ A;  2QWJ A;  3O4P A;  2IAU A;  1NSB A;  2HU4 A;  1F8E A;  2W5O A;  3JU4 A;  5HUG A;  1QBI A;  2XN4 A;  3K3A A;  1OFZ A;  4ZLR A;  1NSD A;  4X4A A;  5GTQ A;  4XOG A;  3K37 A;  4YW2 A;  1INV A;  5NN9 A;  3K39 A;  4QNP A;  2IAO A;  4HZY A;  4WEF A;  4XIO A;  2AEP A;  2GVU A;  2F26 A;  1WCQ A;  4L7C A;  2DG1 A;  1WCS A;  3B7E A;  1NNA A;  4FVK A;  3T1E A;  2W20 A;  3V1S A;  1Z4Y A;  1V0E A;  4AH4 A;  3CL0 A;  1ZGK A;  4GZX A;  5D9C A;  3WN7 A;  2HTU A;  1EUR A;  3DAS A;  2SIM A;  3TIC A;  3O9J A;  5EX7 A;  3A71 A;  4KS3 A;  1IUB A;  2VK7 A;  1C5K A;  2X9M A;  7NN9 A;  3FW0 A;  1NNC A;  4QN6 A;  1ING A;  2HQS A;  4M4N A;  5FZN A;  1NCA N;  3INB A;  4XMI A;  1MS8 A;  4AGI A;  3II7 A;  1RWI A;  4MC7 A;  3ALX A;  4WA3 A;  4D52 A;  2YA7 A;  2DG0 A;  1RWL A;  3KYA A;  2QWI A;  4KS5 A;  1E8V A;  4GZQ A;  3S8Z A;  3Q6T A;  3ADE A;  4MWJ A;  1W1X A;  4HZW A;  2IAR A;  1QLG A;  2Z32 A;  4XJ8 A;  1N1V A;  2XZJ A;  3NN9 A;  4O5T A;  5B2C A;  4FOW A;  1K32 A;  2VWD A;  2HT8 A;  4HIZ A;  4YW5 A;  1SLL A;  3WDZ A;  4B7Q A;  1VCU A;  2W8B A;  1L7F A;  3LI5 A;  3K36 A;  4WEG A;  1CQ1 A;  1F8C A;  4GN8 A;  5GX3 A;  2H2N A;  1IVF A;  3HRP A;  5FNR A;  4GZW A;  4XJ9 A;  3E5Z A;  4KS2 A;  3LI4 A;  2YA8 A;  4WA5 A;  2VW2 A;  3KGG A;  1VCJ A;  1V0Z A;  1SNT A;  1S1D A;  4IMB A;  4GB1 A;  1EUU A;  4GEZ A;  1V2I A;  3OPZ A;  1MR5 A;  3A9G A;  2VSM A;  1MS3 A;  4MJV A;  4QN4 A;  2YA6 A;  3GVJ A;  2POO A;  2QWE A;  3SAN A;  4CPL A;  5GX4 A;  4FOQ A;  1KIT A;  1V3E A;  4D4U A;  4FPF A;  2FLU X;  1CRZ A;  4YW1 A;  2AEQ A;  1MWE A;  3CKZ A;  1E8U A;  4GN7 A;  2ZZK A;  5FWW A;  4MZA A;  4G3N A;  4L7D A;  4XJU A;  1A14 N;  4JF7 A;  2QWK A;  2F12 A;  2IAV A;  3I1C A;  5CGJ A;  4K1J A;  4YZ4 A;  4JML A;  4XYX A;  3VNH A;  4DGR A;  3CL2 A;  1NMB N;  1EUT A;  4GZO A;  3SOQ A;  4N1B A;  4CPO A;  1NN2 A;  1B9S A;  2F25 A;  4K1H A;  4GNA A;  4XHB A;  2IAX A;  4YY8 A;  4FPC A;  1W20 A;  4GZS A;  4XHX A;  4GNC A;  1Z50 A;  4HHO A;  4KS4 A;  4FJ6 A;  5F9T A;  3TI5 A;  4C1Y B;  1NPE A;  2W38 A;  4J9T A;  2GVX A;  2YDT A;  2HTY A;  4I00 A;  4MX0 A;  4XJR A;  3NSS A;  3H6J A;  5HUN A;  2AGS A;  2GHS A;  1BJI A;  1N1T A;  4FPE A;  1IVG A;  5FZJ A;  4XMA A;  2HTV A;  1L7G A;  1V3C A;  2YDP A; 
#chains in the Genus database with same CATH homology
 5FNT A;  2ZW9 A;  2Z32 A;  4IFN X;  2WOZ A;  5FNS A;  4IN4 A;  4IFL X;  5FZN A;  3WDZ A;  4IFJ A;  2ZZK A;  1X2J A;  4CHB A;  4L7C A;  4YY8 A;  4ZGC A;  4L7D A;  2XN4 A;  4ASC A;  4L7B A;  3II7 A;  4ZY3 A;  2ZWA A;  3ZGC A;  5CGJ A;  3VNG A;  1ZGK A;  4IQK A;  3WN7 A;  1X2R A;  4XMB A;  3VNH A;  3ZGD A;  5F72 C;  5FZJ A;  2VPJ A;  5FNR A;  4CH9 A;  5FNU A;  3ADE A;  4N1B A;  2FLU X;  5FNQ A;  1U6D X;  2DYH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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