2DYHA

Crystal structure of the keap1 protein in complexed with the n-terminal region of the nrf2 transcription factor
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
296
structure length
296
Chain Sequence
VGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords Kelch-like ECH-associated protein 1
total genus 66
structure length 296
sequence length 296
ec nomenclature
pdb deposition date 2006-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 2dyhA00
3ZGCA 2ZZKA 5FNTA 2DYHA 1U6DX 4IFNX 3WDZA 4ZGCA 3WN7A 4L7BA 2WOZA 3VNGA 4ASCA 3VNHA 4YY8A 5FNQA 2Z32A 2ZW9A 4IFJA 4L7DA 5FNUA 4IFLX 5FZNA 5F72C 5FZJA 1X2JA 5CGJA 1X2RA 2FLUX 3ADEA 4IN4A 4XMBA 4ZY3A 2XN4A 4CHBA 2ZWAA 2VPJA 5FNSA 4CH9A 5FNRA 3ZGDA 3II7A 4L7CA 4N1BA 1ZGKA 4IQKA
chains in the Genus database with same CATH superfamily
2DYHA 4CPYA 1N1SA 2IAXA 2QWCA 1NNCA 3INBA 4B7RA 4CPNA 4FPCA 4AGTA 2IAPA 2GVVA 2DG1A 4QN6A 1IJQA 1EUSA 4GDJA 1MS8A 1NMBN 4CPOA 1H6LA 1E1AA 3S2KA 5GX4A 2FP9A 3TI3A 3A71A 2CMLA 2GHSA 4FPEA 4CPMA 1INFA 4MWVA 4O5TA 2F27A 2IAOA 4K1IA 1OFZA 4FPFA 2AEPA 3KYAA 4MWYA 1E8TA 2FP8A 3CYEA 3A9HA 1B9SA 1IUBA 1A14N 3S8ZA 2GVUA 4HZZA 4XJAA 4MWQA 1L7FA 1W0OA 1Z4YA 1B9VA 1MS5A 1NNAA 4FJ6A 3SREA 2W38A 3HLHA 4WEGA 4L7CA 4BBWA 4XYXA 4B7NA 5EO8A 1Z50A 4MWUA 3D12A 2QWBA 4XMIA 4DGRA 2HTQA 3FVZA 5FWWA 2WOZA 1INHA 1EUTA 4GZOA 4FPKA 4B7MA 4KS1A 5EO7A 1INVA 4GZSA 4IYGA 3G4HA 2BERA 2IAVA 3NSSA 5GX5A 3IAXA 2F28A 5NN9A 4QN4A 1WCQA 3K36A 3V65B 3ZGCA 4K1HA 2F29A 4QN5A 2ZZKA 1U6DX 4YW3A 4L7BA 1INYA 3ALWA 1S18A 2SIMA 4YZ3A 5H47A 1C9UA 1Z4VA 3TIBA 4M4UA 4NC5A 4CPLA 1X2RA 2FPCA 3ADEA 1N1VA 1CRUA 3FW0A 1PJXA 4MZAA 5FNSA 4HZYA 3ZGDA 2A75A 4UOUA 2RKCA 1ZGKA 2XCYA 3UC1A 3LI5A 4XJUA 1NSBA 1MZ6A 4K1KA 4X6KA 2YDPA 4PWZA 1VCUA 6NN9A 2IAUA 2GVXA 4GZPA 1Z4ZA 3SOVA 5F9TA 2C4AA 1NSCA 3L6VA 4KS5A 5B2CA 5F72C 4YZ5A 1SO7A 1A4QA 4QN7A 2XN4A 4MJUA 2VSKA 3HRPA 2VW2A 2SLIA 1DILA 4FPJA 3W09A 1S0IA 1DIMA 1E8VA 1Z4WA 4GDIA 3O9KA 2W20A 5D9DA 4FOQA 2IASA 4KS2A 2HTYA 5GX3A 1L7HA 2DG0A 2W8BA 4FOYA 4MWRA 3SRGA 4ZGCA 4G3NA 1RWLA 1N1YA 4XJRA 3A72A 2VVZA 4Q1UA 4FOWA 1V3EA 1NCCN 2X9MA 4GN8A 1INGA 1V04A 4JF7A 4C1YB 4FPLA 4XMBA 4GJTA 3KGGA 2QWAA 5FNRA 3II7A 4HZXA 4MWWA 4XIKA 4FPHA 1V0FA 4GNAA 2XZJA 2DSOA 3O9JA 2ISMA 3TI4A 1V0EA 1IVDA 2F12A 4X49A 4XJQA 1N6FA 4GNCA 4YW5A 4IFLX 2H2UA 1XOEA 3Q6TA 4MX0A 2IVZA 1RWIA 2YA6A 4YW1A 3WW9A 1W21A 1IUCA 2ZWAA 1INXA 4HW6A 3NN9A 1W8NA 2FPBA 2HTUA 2IAQA 4WA5A 2F13A 2VW1A 1NMCA 3G4EA 2BATA 2F24A 3BYCA 5EX7A 4XOGA 1SNTA 3H6JA 4H53A 1V2IA 1SLLA 1W8OA 3I1CA 1NCAN 3TICA 2FLUX 4FOVA 2HT7A 4GZWA 4YZ1A 3TI8A 4AH4A 2C4LA 4KS4A 1QBIA 1Z4XA 4I00A 3K37A 2ZB6A 3DR2A 3GVLA 4MJVA 4GEZA 2QWFA 3B7EA 1N7DA 7NN9A 4X47A 1USRA 2QE8A 4FP3A 4IFJA 4D52B 1NN2A 5HX0A 4WA4A 2VK5A 4WEFA 2FHRA 2HT8A 2VPJA 3V64C 4CH9A 2AEQA 3U0SA 4M4NA 3O4PA 1MS4A 2W5NA 4XMAA 1F8BA 2YDTA 2QWGA 3SLIA 2VK6A 2BZDA 1MZ5A 1N6DA 3LI4A 4IFNX 3VNGA 4YW2A 2IAWA 3Q6PA 1KITA 1V3DA 5HUMA 3S94A 2HTWA 4FQ4A 2QWEA 4GN7A 3SALA 1N1TA 4GZQA 2VWDA 1INWA 1NCDN 1E8UA 3OPZA 4IN4A 5GX2A 2HU0A 4UF7A 1QLGA 4MWJA 4HZWA 3D11A 3JU4A 4FP2A 2POOA 3B69A 4YZ4A 4FPYA 5B2DA 4XHBA 3TI6A 2QWDA 2BF6A 1MS3A 3LI3A 3P5BL 4SLIA 3BEQA 2Z32A 2ZW9A 2P4OA 5HUGA 1POOA 2F0ZA 5M1ZA 1IVBA 2VSMA 4CHBA 2OJHA 4FVKA 1F8EA 4FPGA 4DG6A 3TC9A 2VW0A 1NCBN 1NMAN 4C1YA 3CKZA 1SLIA 2HT5A 4XIOA 5D9CA 1USXA 2GVWA 2QWKA 1VCJA 4MC7A 4FPOB 4YY8A 3AMSA 1W0PA 1MR5A 4R40A 1Q7FA 1V0ZA 4X4AA 3WWAA 4Q6KA 3NO0A 4CPZA 4ZY3A 3H71A 1WP5A 3V1SA 4H52A 2HTVA 4B7QA 3GVJA 4KS3A 1BJIA 3DASA 2XZKA 4IMBA 1EURA 3SILA 2F26A 4A0PA 3WN7A 4NCSA 3K38A 2F11A 2VK7A 4B7JA 1A4GA 5FNUA 2QWJA 1MS9A 4XJWA 3CL0A 1S0JA 4QNPA 1X2JA 4GZTA 1CRZA 2V91A 3SOQA 2YA5A 3SOBB 4CSDA 5D9BA 1IVFA 3ALXA 2QWHA 5HUKA 2SILA 1V3BA 1SUUA 4HZVA 3WDZA 4J9TA 3K3AA 3SANA 4ASCA 2H2NA 2IARA 4HHQA 1ZI0A 2HU4A 1F8DA 1MS0A 4L7DA 4XILA 5FNQA 4XJZA 4XE9A 5FZJA 3A9GA 1CVMA 4GB1A 4HHOA 5GX1A 1W1XA 2YA4A 4ZLRA 3S8VA 2AGSA 4D4UA 4NN9A 4D52A 4N1BA 4GN9A 1IVGA 2HTRA 3H72A 5GTQA 4XJ8A 5FNTA 3AMRA 2XZIA 4GNBA 4JMLA 4WA3A 4K1JA 1MWEA 4MWLA 4XHXA 1F8CA 2JKBA 4XJ9A 4K3YA 3VNHA 1CQ1A 3T1EA 1W20A 1NNBA 2F25A 3GVKA 2W5OA 4D52C 4QN3A 4D8SA 5CGJA 2HQSA 1NSDA 1V3CA 3TIAA 1S1DA 1IVCA 1IVEA 4M4VA 4MWXA 4AGIA 4AHAA 1EUUA 2VAQA 1L7GA 3PJQA 4IQKA 3K39A 1WCSA 4FZHA 3E5ZA 1N6EA 4YZ2A 4MZEA 4M3MA 2AH2A 2F10A 4GZXA 5JYYA 1NPEA 3HLIA 2YA7A 5HUNA 1B9TA 4O5SA 3CL2A 5FZNA 2G8SA 2IATA 3TI5A 3Q6KA 4HIZA 2QWIA 2W8BB 2YA8A 2B8HA 1XOGA 1MS1A 3H73A 2ZB5A 1C5KA 1K32A 4YW4A
chains in the Genus database with same CATH topology
3ZGCA 2ZZKA 5FNTA 2DYHA 1U6DX 4IFNX 3WDZA 4ZGCA 3WN7A 4L7BA 2WOZA 3VNGA 4ASCA 3VNHA 4YY8A 5FNQA 2Z32A 2ZW9A 4IFJA 4L7DA 5FNUA 4IFLX 5FZNA 5F72C 5FZJA 1X2JA 5CGJA 1X2RA 2FLUX 3ADEA 4IN4A 4XMBA 4ZY3A 2XN4A 4CHBA 2ZWAA 2VPJA 5FNSA 4CH9A 5FNRA 3ZGDA 3II7A 4L7CA 4N1BA 1ZGKA 4IQKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZGC A;  2ZZK A;  5FNT A;  2DYH A;  1U6D X;  4IFN X;  3WDZ A;  4ZGC A;  3WN7 A;  4L7B A;  2WOZ A;  3VNG A;  4ASC A;  3VNH A;  4YY8 A;  5FNQ A;  2Z32 A;  2ZW9 A;  4IFJ A;  4L7D A;  5FNU A;  4IFL X;  5FZN A;  5F72 C;  5FZJ A;  1X2J A;  5CGJ A;  1X2R A;  2FLU X;  3ADE A;  4IN4 A;  4XMB A;  4ZY3 A;  2XN4 A;  4CHB A;  2ZWA A;  2VPJ A;  5FNS A;  4CH9 A;  5FNR A;  3ZGD A;  3II7 A;  4L7C A;  4N1B A;  1ZGK A;  4IQK A; 
#chains in the Genus database with same CATH topology
 2DYH A;  4CPY A;  1N1S A;  2IAX A;  2QWC A;  1NNC A;  3INB A;  4B7R A;  4CPN A;  4FPC A;  4AGT A;  2IAP A;  2GVV A;  2DG1 A;  4QN6 A;  1IJQ A;  1EUS A;  4GDJ A;  1MS8 A;  1NMB N;  4CPO A;  1H6L A;  1E1A A;  3S2K A;  5GX4 A;  2FP9 A;  3TI3 A;  3A71 A;  2CML A;  2GHS A;  4FPE A;  4CPM A;  1INF A;  4MWV A;  4O5T A;  2F27 A;  2IAO A;  4K1I A;  1OFZ A;  4FPF A;  2AEP A;  3KYA A;  4MWY A;  1E8T A;  2FP8 A;  3CYE A;  3A9H A;  1B9S A;  1IUB A;  1A14 N;  3S8Z A;  2GVU A;  4HZZ A;  4XJA A;  4MWQ A;  1L7F A;  1W0O A;  1Z4Y A;  1B9V A;  1MS5 A;  1NNA A;  4FJ6 A;  3SRE A;  2W38 A;  3HLH A;  4WEG A;  4L7C A;  4BBW A;  4XYX A;  4B7N A;  5EO8 A;  1Z50 A;  4MWU A;  3D12 A;  2QWB A;  4XMI A;  4DGR A;  2HTQ A;  3FVZ A;  5FWW A;  2WOZ A;  1INH A;  1EUT A;  4GZO A;  4FPK A;  4B7M A;  4KS1 A;  5EO7 A;  1INV A;  4GZS A;  4IYG A;  3G4H A;  2BER A;  2IAV A;  3NSS A;  5GX5 A;  3IAX A;  2F28 A;  5NN9 A;  4QN4 A;  1WCQ A;  3K36 A;  3V65 B;  3ZGC A;  4K1H A;  2F29 A;  4QN5 A;  2ZZK A;  1U6D X;  4YW3 A;  4L7B A;  1INY A;  3ALW A;  1S18 A;  2SIM A;  4YZ3 A;  5H47 A;  1C9U A;  1Z4V A;  3TIB A;  4M4U A;  4NC5 A;  4CPL A;  1X2R A;  2FPC A;  3ADE A;  1N1V A;  1CRU A;  3FW0 A;  1PJX A;  4MZA A;  5FNS A;  4HZY A;  3ZGD A;  2A75 A;  4UOU A;  2RKC A;  1ZGK A;  2XCY A;  3UC1 A;  3LI5 A;  4XJU A;  1NSB A;  1MZ6 A;  4K1K A;  4X6K A;  2YDP A;  4PWZ A;  1VCU A;  6NN9 A;  2IAU A;  2GVX A;  4GZP A;  1Z4Z A;  3SOV A;  5F9T A;  2C4A A;  1NSC A;  3L6V A;  4KS5 A;  5B2C A;  5F72 C;  4YZ5 A;  1SO7 A;  1A4Q A;  4QN7 A;  2XN4 A;  4MJU A;  2VSK A;  3HRP A;  2VW2 A;  2SLI A;  1DIL A;  4FPJ A;  3W09 A;  1S0I A;  1DIM A;  1E8V A;  1Z4W A;  4GDI A;  3O9K A;  2W20 A;  5D9D A;  4FOQ A;  2IAS A;  4KS2 A;  2HTY A;  5GX3 A;  1L7H A;  2DG0 A;  2W8B A;  4FOY A;  4MWR A;  3SRG A;  4ZGC A;  4G3N A;  1RWL A;  1N1Y A;  4XJR A;  3A72 A;  2VVZ A;  4Q1U A;  4FOW A;  1V3E A;  1NCC N;  2X9M A;  4GN8 A;  1ING A;  1V04 A;  4JF7 A;  4C1Y B;  4FPL A;  4XMB A;  4GJT A;  3KGG A;  2QWA A;  5FNR A;  3II7 A;  4HZX A;  4MWW A;  4XIK A;  4FPH A;  1V0F A;  4GNA A;  2XZJ A;  2DSO A;  3O9J A;  2ISM A;  3TI4 A;  1V0E A;  1IVD A;  2F12 A;  4X49 A;  4XJQ A;  1N6F A;  4GNC A;  4YW5 A;  4IFL X;  2H2U A;  1XOE A;  3Q6T A;  4MX0 A;  2IVZ A;  1RWI A;  2YA6 A;  4YW1 A;  3WW9 A;  1W21 A;  1IUC A;  2ZWA A;  1INX A;  4HW6 A;  3NN9 A;  1W8N A;  2FPB A;  2HTU A;  2IAQ A;  4WA5 A;  2F13 A;  2VW1 A;  1NMC A;  3G4E A;  2BAT A;  2F24 A;  3BYC A;  5EX7 A;  4XOG A;  1SNT A;  3H6J A;  4H53 A;  1V2I A;  1SLL A;  1W8O A;  3I1C A;  1NCA N;  3TIC A;  2FLU X;  4FOV A;  2HT7 A;  4GZW A;  4YZ1 A;  3TI8 A;  4AH4 A;  2C4L A;  4KS4 A;  1QBI A;  1Z4X A;  4I00 A;  3K37 A;  2ZB6 A;  3DR2 A;  3GVL A;  4MJV A;  4GEZ A;  2QWF A;  3B7E A;  1N7D A;  7NN9 A;  4X47 A;  1USR A;  2QE8 A;  4FP3 A;  4IFJ A;  4D52 B;  1NN2 A;  5HX0 A;  4WA4 A;  2VK5 A;  4WEF A;  2FHR A;  2HT8 A;  2VPJ A;  3V64 C;  4CH9 A;  2AEQ A;  3U0S A;  4M4N A;  3O4P A;  1MS4 A;  2W5N A;  4XMA A;  1F8B A;  2YDT A;  2QWG A;  3SLI A;  2VK6 A;  2BZD A;  1MZ5 A;  1N6D A;  3LI4 A;  4IFN X;  3VNG A;  4YW2 A;  2IAW A;  3Q6P A;  1KIT A;  1V3D A;  5HUM A;  3S94 A;  2HTW A;  4FQ4 A;  2QWE A;  4GN7 A;  3SAL A;  1N1T A;  4GZQ A;  2VWD A;  1INW A;  1NCD N;  1E8U A;  3OPZ A;  4IN4 A;  5GX2 A;  2HU0 A;  4UF7 A;  1QLG A;  4MWJ A;  4HZW A;  3D11 A;  3JU4 A;  4FP2 A;  2POO A;  3B69 A;  4YZ4 A;  4FPY A;  5B2D A;  4XHB A;  3TI6 A;  2QWD A;  2BF6 A;  1MS3 A;  3LI3 A;  3P5B L;  4SLI A;  3BEQ A;  2Z32 A;  2ZW9 A;  2P4O A;  5HUG A;  1POO A;  2F0Z A;  5M1Z A;  1IVB A;  2VSM A;  4CHB A;  2OJH A;  4FVK A;  1F8E A;  4FPG A;  4DG6 A;  3TC9 A;  2VW0 A;  1NCB N;  1NMA N;  4C1Y A;  3CKZ A;  1SLI A;  2HT5 A;  4XIO A;  5D9C A;  1USX A;  2GVW A;  2QWK A;  1VCJ A;  4MC7 A;  4FPO B;  4YY8 A;  3AMS A;  1W0P A;  1MR5 A;  4R40 A;  1Q7F A;  1V0Z A;  4X4A A;  3WWA A;  4Q6K A;  3NO0 A;  4CPZ A;  4ZY3 A;  3H71 A;  1WP5 A;  3V1S A;  4H52 A;  2HTV A;  4B7Q A;  3GVJ A;  4KS3 A;  1BJI A;  3DAS A;  2XZK A;  4IMB A;  1EUR A;  3SIL A;  2F26 A;  4A0P A;  3WN7 A;  4NCS A;  3K38 A;  2F11 A;  2VK7 A;  4B7J A;  1A4G A;  5FNU A;  2QWJ A;  1MS9 A;  4XJW A;  3CL0 A;  1S0J A;  4QNP A;  1X2J A;  4GZT A;  1CRZ A;  2V91 A;  3SOQ A;  2YA5 A;  3SOB B;  4CSD A;  5D9B A;  1IVF A;  3ALX A;  2QWH A;  5HUK A;  2SIL A;  1V3B A;  1SUU A;  4HZV A;  3WDZ A;  4J9T A;  3K3A A;  3SAN A;  4ASC A;  2H2N A;  2IAR A;  4HHQ A;  1ZI0 A;  2HU4 A;  1F8D A;  1MS0 A;  4L7D A;  4XIL A;  5FNQ A;  4XJZ A;  4XE9 A;  5FZJ A;  3A9G A;  1CVM A;  4GB1 A;  4HHO A;  5GX1 A;  1W1X A;  2YA4 A;  4ZLR A;  3S8V A;  2AGS A;  4D4U A;  4NN9 A;  4D52 A;  4N1B A;  4GN9 A;  1IVG A;  2HTR A;  3H72 A;  5GTQ A;  4XJ8 A;  5FNT A;  3AMR A;  2XZI A;  4GNB A;  4JML A;  4WA3 A;  4K1J A;  1MWE A;  4MWL A;  4XHX A;  1F8C A;  2JKB A;  4XJ9 A;  4K3Y A;  3VNH A;  1CQ1 A;  3T1E A;  1W20 A;  1NNB A;  2F25 A;  3GVK A;  2W5O A;  4D52 C;  4QN3 A;  4D8S A;  5CGJ A;  2HQS A;  1NSD A;  1V3C A;  3TIA A;  1S1D A;  1IVC A;  1IVE A;  4M4V A;  4MWX A;  4AGI A;  4AHA A;  1EUU A;  2VAQ A;  1L7G A;  3PJQ A;  4IQK A;  3K39 A;  1WCS A;  4FZH A;  3E5Z A;  1N6E A;  4YZ2 A;  4MZE A;  4M3M A;  2AH2 A;  2F10 A;  4GZX A;  5JYY A;  1NPE A;  3HLI A;  2YA7 A;  5HUN A;  1B9T A;  4O5S A;  3CL2 A;  5FZN A;  2G8S A;  2IAT A;  3TI5 A;  3Q6K A;  4HIZ A;  2QWI A;  2W8B B;  2YA8 A;  2B8H A;  1XOG A;  1MS1 A;  3H73 A;  2ZB5 A;  1C5K A;  1K32 A;  4YW4 A; 
#chains in the Genus database with same CATH homology
 3ZGC A;  2ZZK A;  5FNT A;  2DYH A;  1U6D X;  4IFN X;  3WDZ A;  4ZGC A;  3WN7 A;  4L7B A;  2WOZ A;  3VNG A;  4ASC A;  3VNH A;  4YY8 A;  5FNQ A;  2Z32 A;  2ZW9 A;  4IFJ A;  4L7D A;  5FNU A;  4IFL X;  5FZN A;  5F72 C;  5FZJ A;  1X2J A;  5CGJ A;  1X2R A;  2FLU X;  3ADE A;  4IN4 A;  4XMB A;  4ZY3 A;  2XN4 A;  4CHB A;  2ZWA A;  2VPJ A;  5FNS A;  4CH9 A;  5FNR A;  3ZGD A;  3II7 A;  4L7C A;  4N1B A;  1ZGK A;  4IQK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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