2QWFA

The x-ray structure of a complex of n-acetyl-4-guanidino-6-methyl(propyl)carboxamide-4,5-dihydro-2h-pyran-2-carboxylic acid and a drug resistant variant r292k of tern n9 influenza virus neuraminidase
Total Genus 113
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
388
structure length
388
Chain Sequence
RDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCKDNWQGSNRPVIRIDPVAMTHTSQYICSPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGVNTWLGRTISIASRSGYEMLKVPNALTDDKSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL
5010015020025030035035030025020015010050
020406080100Genus Matrix

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYTI4 (153-156)TVIII1 (331-335)O3 (370-372)TIV14 (357-360)TI3 (147-150)S3 (115-125)S1 (90-91)O4 (92-417)S4 (128-139)S2 (96-102)3H1 (143-145)AH1 (105-110)TI1 (125-128)O2 (112-114)TI2 (139-142)S7 (179-184)TI6 (169-171)TII1 (145-148)S5 (157-162)TI7 (197-200)S8 (189-195)TII2 (162-165)TI5 (168-170)S6 (172-176)TIV1 (185-188)TIV5 (232-235)S12 (251-258)S11 (236-243)TIV2 (198-201)TIV3 (206-209)S9 (202-207)S10 (210-216)TIV4 (217-220)TIV12 (306-309)S14 (276-283)TIV6 (245-248)TIV8 (282-285)S16 (301-306)S13 (261-267)S15 (286-292)TIV13 (324-327)TIV9 (293-296)TI8 (307-310)TIV10 (294-297)S17 (311-316)TI9 (336-339)TIV15 (367-370)S19 (361-364)TII3 (379-382)TI10 (382-385)TIV17 (385-388)O1 (86-88)TII'1 (356-359)TIV7 (257-260)TIV11 (297-300)S20 (374-378)TIV16 (381-384)S18 (353-354)Updating...
connected with : NaN
publication title Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NEURAMINIDASE
total genus 113
structure length 388
sequence length 388
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 1998-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00064 Neur Neuraminidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 2qwfA00
3CL0A 1F8DA 3BEQA 1INHA 2RKCA 4QN3A 4MWWA 1W0OA 1INGA 2VK6A 4B7JA 2ZB5A 4GZOA 4XHBA 4I00A 5HX0A 1N1VA 2W38A 2F11A 3ALWA 4CPYA 1B9VA 4MJUA 5B2CA 3GVJA 2F29A 2A75A 1Z4VA 1N1YA 4WEFA 4GZPA 2BERA 2VVZA 4XYXA 4GZWA 2W5NA 1NCDN 4MZEA 2HTVA 4H52A 4WA4A 4KS2A 1DIMA 4GB1A 4NCSA 2QWDA 1EUUA 1NN2A 7NN9A 2HTRA 3GVKA 3TI3A 1A14N 3NSSA 3B69A 4KS4A 4FPOB 4GZSA 1L7FA 1Z4XA 1NNAA 2VK5A 3K38A 4K1JA 1INXA 2QWHA 2C4AA 4FOVA 4HZYA 1XOEA 2B8HA 4XMAA 2BZDA 1MWEA 4CPMA 2QWKA 2YA5A 1VCUA 2VSMA 4GZQA 2ZB6A 2VWDA 4YW1A 2F24A 2QWEA 2XZIA 4FPGA 4FPJA 2AH2A 4FJ6A 4QNPA 3SILA 4J9TA 1V3DA 4KS5A 1NCBN 2F26A 5NN9A 4QN7A 4CPOA 4MC7A 1NNCA 2YDPA 4MZAA 5HUMA 1NMAN 1IVGA 1B9SA 3H71A 4XIOA 4FP2A 2QWJA 1V0FA 1B9TA 1E8UA 1V3EA 2X9MA 1MR5A 4FPCA 4HZVA 4XOGA 4CPNA 4K1HA 2HU4A 4YW4A 2VW1A 1L7GA 1MS1A 2F25A 4FPKA 1NSCA 1W21A 5M1ZA 3A72A 4XIKA 4GEZA 2CMLA 3K3AA 2QWFA 4FPHA 4FOWA 2F28A 4FPYA 4MWJA 4CPZA 4XJRA 4XJUA 2C4LA 3TICA 4D8SA 1INFA 1MZ6A 4FP3A 2AEQA 1DILA 4HIZA 1S0JA 2SLIA 1W20A 4B7NA 4GDIA 4FVKA 5HUNA 2W20A 3T1EA 1V0ZA 4X4AA 4FZHA 2JKBA 3INBA 3D11A 3SLIA 1E8VA 2HT7A 3ALXA 1A4GA 4XJQA 2YDTA 4YZ5A 6NN9A 1W1XA 3SANA 4X49A 3GVLA 4WEGA 1N1SA 4FOYA 4XJWA 4KS3A 1MS9A 1V2IA 4YW2A 4K3YA 1V0EA 2F13A 4B7RA 1INWA 2XZKA 1SNTA 4QN5A 1F8EA 4K1IA 3A71A 4CPLA 4K1KA 2VK7A 4YZ2A 4B7QA 3W09A 2XCYA 4KS1A 1NMBN 1MZ5A 2BATA 4FPLA 4GZTA 2F12A 1NCCN 4YZ4A 4FOQA 4XMIA 1A4QA 4HZWA 3B7EA 2HT5A 2VSKA 4MWXA 1IVFA 2QWCA 2XZJA 4X6KA 2VW2A 2QWBA 4XHXA 4FQ4A 2FHRA 2YA4A 4XJZA 4MJVA 2HTUA 4XILA 3OPZA 4XJ8A 2HTWA 2VW0A 2HT8A 3TI5A 4X47A 1MS3A 4M3MA 3TI4A 2QWAA 3CKZA 2F27A 4UF7A 3O9KA 1F8CA 4M4NA 1SO7A 4QN4A 4Q6KA 1USXA 3D12A 4MWLA 2YA7A 4NC5A 1IVBA 2HTQA 1MS4A 1L7HA 2SILA 1Z50A 1F8BA 4YW3A 4JF7A 4MWVA 1W8OA 5B2DA 1V3CA 1NMCA 4MWYA 3TI8A 3NN9A 5HUGA 3JU4A 5F9TA 1MS0A 2HU0A 4XJAA 4M4UA 4XJ9A 1EUTA 2F10A 4FPEA 5JYYA 4M4VA 1MS5A 1BJIA 4B7MA 1EUSA 3O9JA 1USRA 2W5OA 4SLIA 1SLIA 1V3BA 3H6JA 1Z4ZA 4HZZA 1Z4YA 4MWUA 1IVEA 3TIBA 4GDJA 3K37A 2AEPA 1IVCA 2YA6A 1INYA 4YZ1A 4MWRA 4XE9A 4FPFA 1XOGA 1WCSA 3PJQA 4GZXA 3TI6A 1KITA 4HZXA 3K36A 3H73A 3CL2A 1W0PA 2YA8A 2BF6A 1NCAN 2F0ZA 1NNBA 4BBWA 2QWGA 1E8TA 3H72A 3CYEA 2SIMA 2QWIA 4MWQA 4WA5A 4NN9A 1WCQA 4DGRA 1SLLA 1W8NA 4YW5A 1N1TA 4YZ3A 2HTYA 1NSBA 3SALA 5HUKA 3TIAA 4QN6A 4H53A 2AGSA 3K39A 1VCJA 1MS8A 1Z4WA 4WA3A 1INVA 1NSDA 4MX0A 1IVDA 4GJTA 1EURA 1S0IA
chains in the Genus database with same CATH superfamily
3CL0A 1F8DA 3BEQA 1INHA 2RKCA 2Z32A 4QN3A 4MWWA 5GX2A 1W0OA 1INGA 2VK6A 2WOZA 4B7JA 4A0PA 3V64C 2ZB5A 2DG1A 4GZOA 4XHBA 4I00A 5HX0A 4IN4A 1N1VA 2W38A 2F11A 1IUCA 3ALWA 4CPYA 1B9VA 4MJUA 1PJXA 5B2CA 5D9DA 3P5BL 3GVJA 2F29A 4L7DA 2A75A 1Z4VA 2DSOA 1N1YA 2VAQA 4WEFA 4GZPA 2BERA 2VVZA 2GHSA 4XYXA 4GZWA 1E1AA 5H47A 4ASCA 2W5NA 1NCDN 4MZEA 1C9UA 2IAOA 2HTVA 4H52A 4WA4A 4KS2A 1DIMA 4GB1A 3G4HA 4NCSA 4PWZA 5F72C 3UC1A 2QWDA 1EUUA 1NN2A 7NN9A 2HTRA 1X2RA 5GX4A 3GVKA 3TI3A 1A14N 3NSSA 2ZWAA 4GN9A 3G4EA 1CRZA 3B69A 4KS4A 3DASA 4R40A 4FPOB 3KYAA 4GZSA 1L7FA 1Z4XA 1NNAA 2VK5A 3K38A 4K1JA 4D4UA 3NO0A 1INXA 2ISMA 3AMRA 3LI3A 1K32A 2QWHA 2C4AA 4ZY3A 4D52C 4FOVA 4HZYA 1XOEA 2POOA 2B8HA 3ADEA 4XMAA 2BZDA 1MWEA 4IQKA 4CPMA 2QWKA 2YA5A 4ZLRA 1VCUA 2VSMA 4GZQA 2ZB6A 2VWDA 2QE8A 4YW1A 2F24A 5FNSA 1SUUA 2QWEA 1CRUA 3O4PA 1IUBA 2XZIA 4FPGA 1CVMA 1WP5A 5FNRA 3WWAA 4FPJA 2AH2A 4FJ6A 4O5SA 4QNPA 3SILA 4J9TA 4IFNX 4YY8A 1N6FA 1V3DA 2H2NA 5FZNA 4KS5A 1RWLA 1N6EA 1NCBN 2F26A 5NN9A 5FNUA 4QN7A 4CPOA 2DYHA 4MC7A 3DR2A 3E5ZA 1NNCA 2YDPA 4MZAA 5HUMA 3V65B 4L7BA 1NMAN 1IVGA 1B9SA 3H71A 4XIOA 4FP2A 2QWJA 1V0FA 3SRGA 4HHOA 3Q6PA 1B9TA 1E8UA 1V3EA 2X9MA 3L6VA 1MR5A 2IAQA 4FPCA 4HZVA 4XOGA 2HQSA 4CPNA 4K1HA 4N1BA 5FNTA 4CH9A 2HU4A 1S18A 4YW4A 2VW1A 1L7GA 2W8BA 1MS1A 2F25A 2H2UA 4FPKA 4IFJA 1NSCA 1W21A 5M1ZA 3A72A 4XIKA 4GEZA 2CMLA 3K3AA 2QWFA 4FPHA 4FOWA 5CGJA 2F28A 2W8BB 4FPYA 4MWJA 3LI5A 1NPEA 4CPZA 4XJRA 3II7A 4XJUA 2C4LA 3A9HA 3TICA 4D8SA 3S94A 1INFA 1MZ6A 4FP3A 4HW6A 2AEQA 1DILA 4HIZA 1S0JA 3KGGA 2SLIA 1H6LA 1W20A 3S8ZA 4B7NA 5FZJA 4GDIA 4FVKA 5HUNA 2W20A 3T1EA 5GX3A 1V0ZA 3SREA 4X4AA 4FZHA 2JKBA 3FVZA 3INBA 2GVXA 3D11A 1QLGA 3SLIA 1E8VA 5GX1A 2HT7A 4UOUA 3ALXA 1A4GA 3A9GA 4XJQA 2YDTA 4YZ5A 6NN9A 1W1XA 1CQ1A 3SANA 4X49A 3GVLA 4WEGA 1N1SA 4FOYA 4XJWA 4KS3A 1MS9A 1V2IA 4YW2A 4K3YA 3ZGCA 2IAWA 1V0EA 2F13A 1X2JA 2IASA 5FWWA 4B7RA 1INWA 4Q1UA 5GX5A 2XZKA 1SNTA 4QN5A 1F8EA 4K1IA 3A71A 4IMBA 4CPLA 4K1KA 2VK7A 4L7CA 2FP8A 3SOQA 2FLUX 4YZ2A 4B7QA 3S8VA 3W09A 2XCYA 4KS1A 1NMBN 1MZ5A 2BATA 4HHQA 4FPLA 4GZTA 4G3NA 1OFZA 2F12A 1NCCN 4AGTA 2IAVA 1N6DA 3WDZA 4GNAA 1V04A 4YZ4A 3HLIA 4FOQA 4XMIA 1A4QA 4HZWA 3B7EA 2HT5A 3I1CA 2VSKA 4MWXA 3HRPA 4GN7A 1IVFA 4JMLA 2QWCA 2XZJA 4X6KA 1C5KA 2VW2A 2QWBA 4XHXA 4FQ4A 3SOVA 2FHRA 2YA4A 4XJZA 4MJVA 2HTUA 4XILA 3U0SA 4AH4A 3OPZA 4XJ8A 2HTWA 2VPJA 2VW0A 2HT8A 4AHAA 3TI5A 4X47A 1MS3A 4M3MA 1N7DA 3TI4A 3VNHA 2QWAA 3CKZA 2F27A 5D9CA 4UF7A 3O9KA 4C1YA 1F8CA 3Q6KA 4M4NA 1SO7A 4QN4A 4GN8A 4D52B 4Q6KA 1USXA 2FPCA 3D12A 2ZW9A 4MWLA 2YA7A 4NC5A 4C1YB 1IVBA 2HTQA 1MS4A 4ZGCA 1L7HA 3SOBB 4CHBA 3VNGA 4DG6A 2SILA 1RWIA 1Z50A 4IFLX 1F8BA 1IJQA 4YW3A 4JF7A 4MWVA 1W8OA 5B2DA 1V3CA 4XMBA 1NMCA 4MWYA 3S2KA 3TI8A 3NN9A 2IVZA 5D9BA 3WN7A 4O5TA 2OJHA 2IAPA 5HUGA 2FPBA 3JU4A 1MS0A 5F9TA 2HU0A 4XJAA 4M4UA 4XJ9A 1EUTA 5EX7A 1Q7FA 2F10A 2GVUA 3FW0A 4FPEA 5JYYA 4M4VA 1MS5A 1BJIA 1POOA 2XN4A 4B7MA 1EUSA 3O9JA 5GTQA 1USRA 2W5OA 4SLIA 1SLIA 1V3BA 3H6JA 1Z4ZA 4HZZA 1Z4YA 3BYCA 4MWUA 1IVEA 5EO8A 3TIBA 2IAXA 4GDJA 1S1DA 2V91A 3K37A 4IYGA 2AEPA 1IVCA 2YA6A 2GVVA 1INYA 4YZ1A 4MWRA 4XE9A 4GNCA 3HLHA 4FPFA 1XOGA 2DG0A 1WCSA 3AMSA 3PJQA 4GZXA 3TI6A 1KITA 4HZXA 3K36A 3H73A 1U6DX 3CL2A 2GVWA 5EO7A 1ZGKA 3Q6TA 2IATA 1W0PA 2YA8A 2BF6A 1NCAN 2P4OA 4AGIA 1ZI0A 2F0ZA 1NNBA 4BBWA 2QWGA 1E8TA 3H72A 3CYEA 2SIMA 2QWIA 4GJTA 4MWQA 4WA5A 1QBIA 4NN9A 1WCQA 4DGRA 1SLLA 1W8NA 3WW9A 2G8SA 4YW5A 1N1TA 2FP9A 2IARA 4YZ3A 2HTYA 1NSBA 3SALA 5HUKA 3TIAA 4QN6A 4CSDA 4H53A 3ZGDA 2AGSA 3K39A 1VCJA 3TC9A 1MS8A 1Z4WA 3IAXA 4GNBA 4WA3A 4D52A 5FNQA 1INVA 3V1SA 1NSDA 3LI4A 4MX0A 2ZZKA 1IVDA 2IAUA 1EURA 1S0IA
chains in the Genus database with same CATH topology
3CL0A 1F8DA 3BEQA 1INHA 2RKCA 4QN3A 4MWWA 1W0OA 1INGA 2VK6A 4B7JA 2ZB5A 4GZOA 4XHBA 4I00A 5HX0A 1N1VA 2W38A 2F11A 3ALWA 4CPYA 1B9VA 4MJUA 5B2CA 3GVJA 2F29A 2A75A 1Z4VA 1N1YA 4WEFA 4GZPA 2BERA 2VVZA 4XYXA 4GZWA 2W5NA 1NCDN 4MZEA 2HTVA 4H52A 4WA4A 4KS2A 1DIMA 4GB1A 4NCSA 2QWDA 1EUUA 1NN2A 7NN9A 2HTRA 3GVKA 3TI3A 1A14N 3NSSA 3B69A 4KS4A 4FPOB 4GZSA 1L7FA 1Z4XA 1NNAA 2VK5A 3K38A 4K1JA 1INXA 2QWHA 2C4AA 4FOVA 4HZYA 1XOEA 2B8HA 4XMAA 2BZDA 1MWEA 4CPMA 2QWKA 2YA5A 1VCUA 2VSMA 4GZQA 2ZB6A 2VWDA 4YW1A 2F24A 2QWEA 2XZIA 4FPGA 4FPJA 2AH2A 4FJ6A 4QNPA 3SILA 4J9TA 1V3DA 2H2NA 4KS5A 1NCBN 2F26A 5NN9A 4QN7A 4CPOA 4MC7A 1NNCA 2YDPA 4MZAA 5HUMA 1NMAN 1IVGA 1B9SA 3H71A 4XIOA 4FP2A 2QWJA 1V0FA 1B9TA 1E8UA 1V3EA 2X9MA 1MR5A 4FPCA 4HZVA 4XOGA 4CPNA 4K1HA 2HU4A 1S18A 4YW4A 2VW1A 1L7GA 1MS1A 2F25A 2H2UA 4FPKA 1NSCA 1W21A 5M1ZA 3A72A 4XIKA 4GEZA 2CMLA 3K3AA 2QWFA 4FPHA 4FOWA 2F28A 4FPYA 4MWJA 4CPZA 4XJRA 4XJUA 2C4LA 3TICA 4D8SA 1INFA 1MZ6A 4FP3A 2AEQA 1DILA 4HIZA 1S0JA 2SLIA 1W20A 4B7NA 4GDIA 4FVKA 5HUNA 2W20A 3T1EA 1V0ZA 4X4AA 4FZHA 2JKBA 3INBA 3D11A 3SLIA 1E8VA 2HT7A 3ALXA 1A4GA 4XJQA 2YDTA 4YZ5A 6NN9A 1W1XA 3SANA 4X49A 3GVLA 4WEGA 1N1SA 4FOYA 4XJWA 4KS3A 1MS9A 1V2IA 4YW2A 4K3YA 1V0EA 2F13A 4B7RA 1INWA 2XZKA 1SNTA 4QN5A 1F8EA 4K1IA 3A71A 4CPLA 4K1KA 2VK7A 4YZ2A 4B7QA 3W09A 2XCYA 4KS1A 1NMBN 1MZ5A 2BATA 4FPLA 4GZTA 2F12A 1NCCN 4YZ4A 4FOQA 4XMIA 1A4QA 4HZWA 3B7EA 2HT5A 2VSKA 4MWXA 1IVFA 2QWCA 2XZJA 4X6KA 2VW2A 2QWBA 4XHXA 4FQ4A 2FHRA 2YA4A 4XJZA 4MJVA 2HTUA 4XILA 3OPZA 4XJ8A 2HTWA 2VW0A 2HT8A 3TI5A 4X47A 1MS3A 4M3MA 3TI4A 2QWAA 3CKZA 2F27A 4UF7A 3O9KA 1F8CA 4M4NA 1SO7A 4QN4A 4Q6KA 1USXA 3D12A 4MWLA 2YA7A 4NC5A 1IVBA 2HTQA 1MS4A 1L7HA 2SILA 1Z50A 1F8BA 4YW3A 4JF7A 4MWVA 1W8OA 5B2DA 1V3CA 1NMCA 4MWYA 3TI8A 3NN9A 5HUGA 3JU4A 5F9TA 1MS0A 2HU0A 4XJAA 4M4UA 4XJ9A 1EUTA 2F10A 4FPEA 5JYYA 4M4VA 1MS5A 1BJIA 4B7MA 1EUSA 3O9JA 1USRA 2W5OA 4SLIA 1SLIA 1V3BA 3H6JA 1Z4ZA 4HZZA 1Z4YA 4MWUA 1IVEA 3TIBA 4GDJA 1S1DA 3K37A 2AEPA 1IVCA 2YA6A 1INYA 4YZ1A 4MWRA 4XE9A 4FPFA 1XOGA 1WCSA 3PJQA 4GZXA 3TI6A 1KITA 4HZXA 3K36A 3H73A 3CL2A 1W0PA 2YA8A 2BF6A 1NCAN 2F0ZA 1NNBA 4BBWA 2QWGA 1E8TA 3H72A 3CYEA 2SIMA 2QWIA 4MWQA 4WA5A 4NN9A 1WCQA 4DGRA 1SLLA 1W8NA 4YW5A 1N1TA 4YZ3A 2HTYA 1NSBA 3SALA 5HUKA 3TIAA 4QN6A 4H53A 2AGSA 3K39A 1VCJA 1MS8A 1Z4WA 4WA3A 1INVA 1NSDA 4MX0A 1IVDA 4GJTA 1EURA 1S0IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CL0 A;  1F8D A;  3BEQ A;  1INH A;  2RKC A;  4QN3 A;  4MWW A;  1W0O A;  1ING A;  2VK6 A;  4B7J A;  2ZB5 A;  4GZO A;  4XHB A;  4I00 A;  5HX0 A;  1N1V A;  2W38 A;  2F11 A;  3ALW A;  4CPY A;  1B9V A;  4MJU A;  5B2C A;  3GVJ A;  2F29 A;  2A75 A;  1Z4V A;  1N1Y A;  4WEF A;  4GZP A;  2BER A;  2VVZ A;  4XYX A;  4GZW A;  2W5N A;  1NCD N;  4MZE A;  2HTV A;  4H52 A;  4WA4 A;  4KS2 A;  1DIM A;  4GB1 A;  4NCS A;  2QWD A;  1EUU A;  1NN2 A;  7NN9 A;  2HTR A;  3GVK A;  3TI3 A;  1A14 N;  3NSS A;  3B69 A;  4KS4 A;  4FPO B;  4GZS A;  1L7F A;  1Z4X A;  1NNA A;  2VK5 A;  3K38 A;  4K1J A;  1INX A;  2QWH A;  2C4A A;  4FOV A;  4HZY A;  1XOE A;  2B8H A;  4XMA A;  2BZD A;  1MWE A;  4CPM A;  2QWK A;  2YA5 A;  1VCU A;  2VSM A;  4GZQ A;  2ZB6 A;  2VWD A;  4YW1 A;  2F24 A;  2QWE A;  2XZI A;  4FPG A;  4FPJ A;  2AH2 A;  4FJ6 A;  4QNP A;  3SIL A;  4J9T A;  1V3D A;  4KS5 A;  1NCB N;  2F26 A;  5NN9 A;  4QN7 A;  4CPO A;  4MC7 A;  1NNC A;  2YDP A;  4MZA A;  5HUM A;  1NMA N;  1IVG A;  1B9S A;  3H71 A;  4XIO A;  4FP2 A;  2QWJ A;  1V0F A;  1B9T A;  1E8U A;  1V3E A;  2X9M A;  1MR5 A;  4FPC A;  4HZV A;  4XOG A;  4CPN A;  4K1H A;  2HU4 A;  4YW4 A;  2VW1 A;  1L7G A;  1MS1 A;  2F25 A;  4FPK A;  1NSC A;  1W21 A;  5M1Z A;  3A72 A;  4XIK A;  4GEZ A;  2CML A;  3K3A A;  2QWF A;  4FPH A;  4FOW A;  2F28 A;  4FPY A;  4MWJ A;  4CPZ A;  4XJR A;  4XJU A;  2C4L A;  3TIC A;  4D8S A;  1INF A;  1MZ6 A;  4FP3 A;  2AEQ A;  1DIL A;  4HIZ A;  1S0J A;  2SLI A;  1W20 A;  4B7N A;  4GDI A;  4FVK A;  5HUN A;  2W20 A;  3T1E A;  1V0Z A;  4X4A A;  4FZH A;  2JKB A;  3INB A;  3D11 A;  3SLI A;  1E8V A;  2HT7 A;  3ALX A;  1A4G A;  4XJQ A;  2YDT A;  4YZ5 A;  6NN9 A;  1W1X A;  3SAN A;  4X49 A;  3GVL A;  4WEG A;  1N1S A;  4FOY A;  4XJW A;  4KS3 A;  1MS9 A;  1V2I A;  4YW2 A;  4K3Y A;  1V0E A;  2F13 A;  4B7R A;  1INW A;  2XZK A;  1SNT A;  4QN5 A;  1F8E A;  4K1I A;  3A71 A;  4CPL A;  4K1K A;  2VK7 A;  4YZ2 A;  4B7Q A;  3W09 A;  2XCY A;  4KS1 A;  1NMB N;  1MZ5 A;  2BAT A;  4FPL A;  4GZT A;  2F12 A;  1NCC N;  4YZ4 A;  4FOQ A;  4XMI A;  1A4Q A;  4HZW A;  3B7E A;  2HT5 A;  2VSK A;  4MWX A;  1IVF A;  2QWC A;  2XZJ A;  4X6K A;  2VW2 A;  2QWB A;  4XHX A;  4FQ4 A;  2FHR A;  2YA4 A;  4XJZ A;  4MJV A;  2HTU A;  4XIL A;  3OPZ A;  4XJ8 A;  2HTW A;  2VW0 A;  2HT8 A;  3TI5 A;  4X47 A;  1MS3 A;  4M3M A;  3TI4 A;  2QWA A;  3CKZ A;  2F27 A;  4UF7 A;  3O9K A;  1F8C A;  4M4N A;  1SO7 A;  4QN4 A;  4Q6K A;  1USX A;  3D12 A;  4MWL A;  2YA7 A;  4NC5 A;  1IVB A;  2HTQ A;  1MS4 A;  1L7H A;  2SIL A;  1Z50 A;  1F8B A;  4YW3 A;  4JF7 A;  4MWV A;  1W8O A;  5B2D A;  1V3C A;  1NMC A;  4MWY A;  3TI8 A;  3NN9 A;  5HUG A;  3JU4 A;  5F9T A;  1MS0 A;  2HU0 A;  4XJA A;  4M4U A;  4XJ9 A;  1EUT A;  2F10 A;  4FPE A;  5JYY A;  4M4V A;  1MS5 A;  1BJI A;  4B7M A;  1EUS A;  3O9J A;  1USR A;  2W5O A;  4SLI A;  1SLI A;  1V3B A;  3H6J A;  1Z4Z A;  4HZZ A;  1Z4Y A;  4MWU A;  1IVE A;  3TIB A;  4GDJ A;  3K37 A;  2AEP A;  1IVC A;  2YA6 A;  1INY A;  4YZ1 A;  4MWR A;  4XE9 A;  4FPF A;  1XOG A;  1WCS A;  3PJQ A;  4GZX A;  3TI6 A;  1KIT A;  4HZX A;  3K36 A;  3H73 A;  3CL2 A;  1W0P A;  2YA8 A;  2BF6 A;  1NCA N;  2F0Z A;  1NNB A;  4BBW A;  2QWG A;  1E8T A;  3H72 A;  3CYE A;  2SIM A;  2QWI A;  4MWQ A;  4WA5 A;  4NN9 A;  1WCQ A;  4DGR A;  1SLL A;  1W8N A;  4YW5 A;  1N1T A;  4YZ3 A;  2HTY A;  1NSB A;  3SAL A;  5HUK A;  3TIA A;  4QN6 A;  4H53 A;  2AGS A;  3K39 A;  1VCJ A;  1MS8 A;  1Z4W A;  4WA3 A;  1INV A;  1NSD A;  4MX0 A;  1IVD A;  4GJT A;  1EUR A;  1S0I A; 
#chains in the Genus database with same CATH topology
 3CL0 A;  1F8D A;  3BEQ A;  1INH A;  2RKC A;  2Z32 A;  4QN3 A;  4MWW A;  5GX2 A;  1W0O A;  1ING A;  2VK6 A;  2WOZ A;  4B7J A;  4A0P A;  3V64 C;  2ZB5 A;  2DG1 A;  4GZO A;  4XHB A;  4I00 A;  5HX0 A;  4IN4 A;  1N1V A;  2W38 A;  2F11 A;  1IUC A;  3ALW A;  4CPY A;  1B9V A;  4MJU A;  1PJX A;  5B2C A;  5D9D A;  3P5B L;  3GVJ A;  2F29 A;  4L7D A;  2A75 A;  1Z4V A;  2DSO A;  1N1Y A;  2VAQ A;  4WEF A;  4GZP A;  2BER A;  2VVZ A;  2GHS A;  4XYX A;  4GZW A;  1E1A A;  5H47 A;  4ASC A;  2W5N A;  1NCD N;  4MZE A;  1C9U A;  2IAO A;  2HTV A;  4H52 A;  4WA4 A;  4KS2 A;  1DIM A;  4GB1 A;  3G4H A;  4NCS A;  4PWZ A;  5F72 C;  3UC1 A;  2QWD A;  1EUU A;  1NN2 A;  7NN9 A;  2HTR A;  1X2R A;  5GX4 A;  3GVK A;  3TI3 A;  1A14 N;  3NSS A;  2ZWA A;  4GN9 A;  3G4E A;  1CRZ A;  3B69 A;  4KS4 A;  3DAS A;  4R40 A;  4FPO B;  3KYA A;  4GZS A;  1L7F A;  1Z4X A;  1NNA A;  2VK5 A;  3K38 A;  4K1J A;  4D4U A;  3NO0 A;  1INX A;  2ISM A;  3AMR A;  3LI3 A;  1K32 A;  2QWH A;  2C4A A;  4ZY3 A;  4D52 C;  4FOV A;  4HZY A;  1XOE A;  2POO A;  2B8H A;  3ADE A;  4XMA A;  2BZD A;  1MWE A;  4IQK A;  4CPM A;  2QWK A;  2YA5 A;  4ZLR A;  1VCU A;  2VSM A;  4GZQ A;  2ZB6 A;  2VWD A;  2QE8 A;  4YW1 A;  2F24 A;  5FNS A;  1SUU A;  2QWE A;  1CRU A;  3O4P A;  1IUB A;  2XZI A;  4FPG A;  1CVM A;  1WP5 A;  5FNR A;  3WWA A;  4FPJ A;  2AH2 A;  4FJ6 A;  4O5S A;  4QNP A;  3SIL A;  4J9T A;  4IFN X;  4YY8 A;  1N6F A;  1V3D A;  2H2N A;  5FZN A;  4KS5 A;  1RWL A;  1N6E A;  1NCB N;  2F26 A;  5NN9 A;  5FNU A;  4QN7 A;  4CPO A;  2DYH A;  4MC7 A;  3DR2 A;  3E5Z A;  1NNC A;  2YDP A;  4MZA A;  5HUM A;  3V65 B;  4L7B A;  1NMA N;  1IVG A;  1B9S A;  3H71 A;  4XIO A;  4FP2 A;  2QWJ A;  1V0F A;  3SRG A;  4HHO A;  3Q6P A;  1B9T A;  1E8U A;  1V3E A;  2X9M A;  3L6V A;  1MR5 A;  2IAQ A;  4FPC A;  4HZV A;  4XOG A;  2HQS A;  4CPN A;  4K1H A;  4N1B A;  5FNT A;  4CH9 A;  2HU4 A;  1S18 A;  4YW4 A;  2VW1 A;  1L7G A;  2W8B A;  1MS1 A;  2F25 A;  2H2U A;  4FPK A;  4IFJ A;  1NSC A;  1W21 A;  5M1Z A;  3A72 A;  4XIK A;  4GEZ A;  2CML A;  3K3A A;  2QWF A;  4FPH A;  4FOW A;  5CGJ A;  2F28 A;  2W8B B;  4FPY A;  4MWJ A;  3LI5 A;  1NPE A;  4CPZ A;  4XJR A;  3II7 A;  4XJU A;  2C4L A;  3A9H A;  3TIC A;  4D8S A;  3S94 A;  1INF A;  1MZ6 A;  4FP3 A;  4HW6 A;  2AEQ A;  1DIL A;  4HIZ A;  1S0J A;  3KGG A;  2SLI A;  1H6L A;  1W20 A;  3S8Z A;  4B7N A;  5FZJ A;  4GDI A;  4FVK A;  5HUN A;  2W20 A;  3T1E A;  5GX3 A;  1V0Z A;  3SRE A;  4X4A A;  4FZH A;  2JKB A;  3FVZ A;  3INB A;  2GVX A;  3D11 A;  1QLG A;  3SLI A;  1E8V A;  5GX1 A;  2HT7 A;  4UOU A;  3ALX A;  1A4G A;  3A9G A;  4XJQ A;  2YDT A;  4YZ5 A;  6NN9 A;  1W1X A;  1CQ1 A;  3SAN A;  4X49 A;  3GVL A;  4WEG A;  1N1S A;  4FOY A;  4XJW A;  4KS3 A;  1MS9 A;  1V2I A;  4YW2 A;  4K3Y A;  3ZGC A;  2IAW A;  1V0E A;  2F13 A;  1X2J A;  2IAS A;  5FWW A;  4B7R A;  1INW A;  4Q1U A;  5GX5 A;  2XZK A;  1SNT A;  4QN5 A;  1F8E A;  4K1I A;  3A71 A;  4IMB A;  4CPL A;  4K1K A;  2VK7 A;  4L7C A;  2FP8 A;  3SOQ A;  2FLU X;  4YZ2 A;  4B7Q A;  3S8V A;  3W09 A;  2XCY A;  4KS1 A;  1NMB N;  1MZ5 A;  2BAT A;  4HHQ A;  4FPL A;  4GZT A;  4G3N A;  1OFZ A;  2F12 A;  1NCC N;  4AGT A;  2IAV A;  1N6D A;  3WDZ A;  4GNA A;  1V04 A;  4YZ4 A;  3HLI A;  4FOQ A;  4XMI A;  1A4Q A;  4HZW A;  3B7E A;  2HT5 A;  3I1C A;  2VSK A;  4MWX A;  3HRP A;  4GN7 A;  1IVF A;  4JML A;  2QWC A;  2XZJ A;  4X6K A;  1C5K A;  2VW2 A;  2QWB A;  4XHX A;  4FQ4 A;  3SOV A;  2FHR A;  2YA4 A;  4XJZ A;  4MJV A;  2HTU A;  4XIL A;  3U0S A;  4AH4 A;  3OPZ A;  4XJ8 A;  2HTW A;  2VPJ A;  2VW0 A;  2HT8 A;  4AHA A;  3TI5 A;  4X47 A;  1MS3 A;  4M3M A;  1N7D A;  3TI4 A;  3VNH A;  2QWA A;  3CKZ A;  2F27 A;  5D9C A;  4UF7 A;  3O9K A;  4C1Y A;  1F8C A;  3Q6K A;  4M4N A;  1SO7 A;  4QN4 A;  4GN8 A;  4D52 B;  4Q6K A;  1USX A;  2FPC A;  3D12 A;  2ZW9 A;  4MWL A;  2YA7 A;  4NC5 A;  4C1Y B;  1IVB A;  2HTQ A;  1MS4 A;  4ZGC A;  1L7H A;  3SOB B;  4CHB A;  3VNG A;  4DG6 A;  2SIL A;  1RWI A;  1Z50 A;  4IFL X;  1F8B A;  1IJQ A;  4YW3 A;  4JF7 A;  4MWV A;  1W8O A;  5B2D A;  1V3C A;  4XMB A;  1NMC A;  4MWY A;  3S2K A;  3TI8 A;  3NN9 A;  2IVZ A;  5D9B A;  3WN7 A;  4O5T A;  2OJH A;  2IAP A;  5HUG A;  2FPB A;  3JU4 A;  1MS0 A;  5F9T A;  2HU0 A;  4XJA A;  4M4U A;  4XJ9 A;  1EUT A;  5EX7 A;  1Q7F A;  2F10 A;  2GVU A;  3FW0 A;  4FPE A;  5JYY A;  4M4V A;  1MS5 A;  1BJI A;  1POO A;  2XN4 A;  4B7M A;  1EUS A;  3O9J A;  5GTQ A;  1USR A;  2W5O A;  4SLI A;  1SLI A;  1V3B A;  3H6J A;  1Z4Z A;  4HZZ A;  1Z4Y A;  3BYC A;  4MWU A;  1IVE A;  5EO8 A;  3TIB A;  2IAX A;  4GDJ A;  1S1D A;  2V91 A;  3K37 A;  4IYG A;  2AEP A;  1IVC A;  2YA6 A;  2GVV A;  1INY A;  4YZ1 A;  4MWR A;  4XE9 A;  4GNC A;  3HLH A;  4FPF A;  1XOG A;  2DG0 A;  1WCS A;  3AMS A;  3PJQ A;  4GZX A;  3TI6 A;  1KIT A;  4HZX A;  3K36 A;  3H73 A;  1U6D X;  3CL2 A;  2GVW A;  5EO7 A;  1ZGK A;  3Q6T A;  2IAT A;  1W0P A;  2YA8 A;  2BF6 A;  1NCA N;  2P4O A;  4AGI A;  1ZI0 A;  2F0Z A;  1NNB A;  4BBW A;  2QWG A;  1E8T A;  3H72 A;  3CYE A;  2SIM A;  2QWI A;  4GJT A;  4MWQ A;  4WA5 A;  1QBI A;  4NN9 A;  1WCQ A;  4DGR A;  1SLL A;  1W8N A;  3WW9 A;  2G8S A;  4YW5 A;  1N1T A;  2FP9 A;  2IAR A;  4YZ3 A;  2HTY A;  1NSB A;  3SAL A;  5HUK A;  3TIA A;  4QN6 A;  4CSD A;  4H53 A;  3ZGD A;  2AGS A;  3K39 A;  1VCJ A;  3TC9 A;  1MS8 A;  1Z4W A;  3IAX A;  4GNB A;  4WA3 A;  4D52 A;  5FNQ A;  1INV A;  3V1S A;  1NSD A;  3LI4 A;  4MX0 A;  2ZZK A;  1IVD A;  2IAU A;  1EUR A;  1S0I A; 
#chains in the Genus database with same CATH homology
 3CL0 A;  1F8D A;  3BEQ A;  1INH A;  2RKC A;  4QN3 A;  4MWW A;  1W0O A;  1ING A;  2VK6 A;  4B7J A;  2ZB5 A;  4GZO A;  4XHB A;  4I00 A;  5HX0 A;  1N1V A;  2W38 A;  2F11 A;  3ALW A;  4CPY A;  1B9V A;  4MJU A;  5B2C A;  3GVJ A;  2F29 A;  2A75 A;  1Z4V A;  1N1Y A;  4WEF A;  4GZP A;  2BER A;  2VVZ A;  4XYX A;  4GZW A;  2W5N A;  1NCD N;  4MZE A;  2HTV A;  4H52 A;  4WA4 A;  4KS2 A;  1DIM A;  4GB1 A;  4NCS A;  2QWD A;  1EUU A;  1NN2 A;  7NN9 A;  2HTR A;  3GVK A;  3TI3 A;  1A14 N;  3NSS A;  3B69 A;  4KS4 A;  4FPO B;  4GZS A;  1L7F A;  1Z4X A;  1NNA A;  2VK5 A;  3K38 A;  4K1J A;  1INX A;  2QWH A;  2C4A A;  4FOV A;  4HZY A;  1XOE A;  2B8H A;  4XMA A;  2BZD A;  1MWE A;  4CPM A;  2QWK A;  2YA5 A;  1VCU A;  2VSM A;  4GZQ A;  2ZB6 A;  2VWD A;  4YW1 A;  2F24 A;  2QWE A;  2XZI A;  4FPG A;  4FPJ A;  2AH2 A;  4FJ6 A;  4QNP A;  3SIL A;  4J9T A;  1V3D A;  2H2N A;  4KS5 A;  1NCB N;  2F26 A;  5NN9 A;  4QN7 A;  4CPO A;  4MC7 A;  1NNC A;  2YDP A;  4MZA A;  5HUM A;  1NMA N;  1IVG A;  1B9S A;  3H71 A;  4XIO A;  4FP2 A;  2QWJ A;  1V0F A;  1B9T A;  1E8U A;  1V3E A;  2X9M A;  1MR5 A;  4FPC A;  4HZV A;  4XOG A;  4CPN A;  4K1H A;  2HU4 A;  1S18 A;  4YW4 A;  2VW1 A;  1L7G A;  1MS1 A;  2F25 A;  2H2U A;  4FPK A;  1NSC A;  1W21 A;  5M1Z A;  3A72 A;  4XIK A;  4GEZ A;  2CML A;  3K3A A;  2QWF A;  4FPH A;  4FOW A;  2F28 A;  4FPY A;  4MWJ A;  4CPZ A;  4XJR A;  4XJU A;  2C4L A;  3TIC A;  4D8S A;  1INF A;  1MZ6 A;  4FP3 A;  2AEQ A;  1DIL A;  4HIZ A;  1S0J A;  2SLI A;  1W20 A;  4B7N A;  4GDI A;  4FVK A;  5HUN A;  2W20 A;  3T1E A;  1V0Z A;  4X4A A;  4FZH A;  2JKB A;  3INB A;  3D11 A;  3SLI A;  1E8V A;  2HT7 A;  3ALX A;  1A4G A;  4XJQ A;  2YDT A;  4YZ5 A;  6NN9 A;  1W1X A;  3SAN A;  4X49 A;  3GVL A;  4WEG A;  1N1S A;  4FOY A;  4XJW A;  4KS3 A;  1MS9 A;  1V2I A;  4YW2 A;  4K3Y A;  1V0E A;  2F13 A;  4B7R A;  1INW A;  2XZK A;  1SNT A;  4QN5 A;  1F8E A;  4K1I A;  3A71 A;  4CPL A;  4K1K A;  2VK7 A;  4YZ2 A;  4B7Q A;  3W09 A;  2XCY A;  4KS1 A;  1NMB N;  1MZ5 A;  2BAT A;  4FPL A;  4GZT A;  2F12 A;  1NCC N;  4YZ4 A;  4FOQ A;  4XMI A;  1A4Q A;  4HZW A;  3B7E A;  2HT5 A;  2VSK A;  4MWX A;  1IVF A;  2QWC A;  2XZJ A;  4X6K A;  2VW2 A;  2QWB A;  4XHX A;  4FQ4 A;  2FHR A;  2YA4 A;  4XJZ A;  4MJV A;  2HTU A;  4XIL A;  3OPZ A;  4XJ8 A;  2HTW A;  2VW0 A;  2HT8 A;  3TI5 A;  4X47 A;  1MS3 A;  4M3M A;  3TI4 A;  2QWA A;  3CKZ A;  2F27 A;  4UF7 A;  3O9K A;  1F8C A;  4M4N A;  1SO7 A;  4QN4 A;  4Q6K A;  1USX A;  3D12 A;  4MWL A;  2YA7 A;  4NC5 A;  1IVB A;  2HTQ A;  1MS4 A;  1L7H A;  2SIL A;  1Z50 A;  1F8B A;  4YW3 A;  4JF7 A;  4MWV A;  1W8O A;  5B2D A;  1V3C A;  1NMC A;  4MWY A;  3TI8 A;  3NN9 A;  5HUG A;  3JU4 A;  5F9T A;  1MS0 A;  2HU0 A;  4XJA A;  4M4U A;  4XJ9 A;  1EUT A;  2F10 A;  4FPE A;  5JYY A;  4M4V A;  1MS5 A;  1BJI A;  4B7M A;  1EUS A;  3O9J A;  1USR A;  2W5O A;  4SLI A;  1SLI A;  1V3B A;  3H6J A;  1Z4Z A;  4HZZ A;  1Z4Y A;  4MWU A;  1IVE A;  3TIB A;  4GDJ A;  1S1D A;  3K37 A;  2AEP A;  1IVC A;  2YA6 A;  1INY A;  4YZ1 A;  4MWR A;  4XE9 A;  4FPF A;  1XOG A;  1WCS A;  3PJQ A;  4GZX A;  3TI6 A;  1KIT A;  4HZX A;  3K36 A;  3H73 A;  3CL2 A;  1W0P A;  2YA8 A;  2BF6 A;  1NCA N;  2F0Z A;  1NNB A;  4BBW A;  2QWG A;  1E8T A;  3H72 A;  3CYE A;  2SIM A;  2QWI A;  4MWQ A;  4WA5 A;  4NN9 A;  1WCQ A;  4DGR A;  1SLL A;  1W8N A;  4YW5 A;  1N1T A;  4YZ3 A;  2HTY A;  1NSB A;  3SAL A;  5HUK A;  3TIA A;  4QN6 A;  4H53 A;  2AGS A;  3K39 A;  1VCJ A;  1MS8 A;  1Z4W A;  4WA3 A;  1INV A;  1NSD A;  4MX0 A;  1IVD A;  4GJT A;  1EUR A;  1S0I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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