2DYHA

Crystal structure of the keap1 protein in complexed with the n-terminal region of the nrf2 transcription factor
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
296
structure length
296
Chain Sequence
VGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEPCRKQIDQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords Kelch-like ECH-associated protein 1
total genus 66
structure length 296
sequence length 296
ec nomenclature
pdb deposition date 2006-09-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 2dyhA00
4L7DA 5FNTA 5FNUA 1U6DX 2WOZA 2DYHA 4YY8A 1X2RA 2XN4A 3VNHA 4L7BA 4IFLX 3ADEA 3VNGA 4IFJA 4CH9A 2ZW9A 5FNRA 5CGJA 5F72C 2VPJA 4ZGCA 5FNSA 3ZGCA 4CHBA 4ZY3A 5FZJA 4L7CA 4IFNX 2Z32A 5FNQA 2ZWAA 2FLUX 4XMBA 4IQKA 4N1BA 3II7A 5FZNA 3WDZA 3WN7A 3ZGDA 4ASCA 1ZGKA 1X2JA 4IN4A 2ZZKA
chains in the Genus database with same CATH superfamily
4A0PA 3KYAA 4Q6KA 3WW9A 4GN9A 3S8ZA 3SOVA 3VNGA 2F27A 4H52A 4B7RA 1V0FA 1NCDN 3TIBA 4GN8A 4O5SA 3DR2A 3KGGA 3TC9A 1W1XA 2VW1A 3ZGCA 1IVGA 1S1DA 4MWXA 5B2DA 2HTYA 3K39A 4UOUA 4FPKA 4X49A 3V65B 3JU4A 4CPYA 4D52B 4B7JA 1E1AA 4YZ5A 4UF7A 5D9BA 5GX5A 1SLIA 4H53A 3P5BL 5FWWA 1K32A 1NNBA 4XMAA 1N6FA 2YA4A 4YW2A 1NSDA 3TI6A 1A14N 4MJUA 2VW0A 2HT8A 2QWFA 4IFNX 4GZTA 2W8BA 3TI4A 4K1KA 3WDZA 2F13A 4YZ2A 4XIOA 3K38A 2BZDA 1N7DA 4KS5A 4MWJA 3G4EA 5GX4A 4QN4A 4MWQA 3LI4A 4XJRA 2AEQA 4XMIA 3SREA 4B7NA 4MC7A 4QNPA 2VK6A 2HU0A 3TICA 1F8DA 1INXA 4IMBA 4FPHA 4AHAA 4FVKA 1EUUA 4GZXA 2F11A 3A71A 1DIMA 4MWWA 3CL2A 4KS3A 1W0OA 4KS2A 4SLIA 3CKZA 2POOA 4FOQA 3FVZA 4YZ1A 2OJHA 2QE8A 4IYGA 1Z4XA 4Q1UA 3W09A 1WP5A 1CQ1A 4CSDA 4HHQA 2YA5A 5H47A 1INYA 2FLUX 2XZIA 1Z50A 1Q7FA 3II7A 2JKBA 1EUSA 4MWVA 4YZ4A 3A72A 3NSSA 3A9GA 4R40A 2W38A 2IAQA 4FOVA 2IARA 2VSMA 1XOEA 4XIKA 3IAXA 4CPMA 1V3CA 4GZOA 2VAQA 4K1HA 4GZWA 2QWKA 4MWUA 1L7GA 1F8EA 3B69A 2Z32A 1KITA 1NNCA 4AGIA 3LI3A 2F0ZA 1A4GA 1NCCN 1X2JA 4FPYA 4IN4A 4FPOB 1MS4A 4QN7A 4YW4A 4GNBA 3VNHA 5EX7A 4HZXA 4YW5A 4FPCA 2F25A 1NMCA 3TIAA 4CPOA 4PWZA 5GX2A 2YDTA 3D11A 2AGSA 4NC5A 4QN3A 1EURA 5GTQA 2H2NA 1INWA 5FZJA 3SOQA 3CL0A 2FHRA 2GVXA 4HZVA 2GVUA 5HUMA 3V64C 1VCUA 4JMLA 4C1YB 4FZHA 3SLIA 3WN7A 3H6JA 4K3YA 1IUCA 1MR5A 5HX0A 4GNCA 2HTUA 3E5ZA 3O4PA 1CRZA 1E8UA 2DYHA 3TI8A 2VSKA 2HTQA 4K1IA 2W20A 2ZB6A 2YA7A 4AH4A 3O9KA 5CGJA 4YW3A 4M4UA 1B9VA 1N6DA 2H2UA 1Z4WA 2VPJA 1INHA 2V91A 4L7CA 2YDPA 1WCQA 1E8VA 5FNQA 1MZ6A 2C4AA 1B9TA 1N1SA 4ASCA 1XOGA 7NN9A 1MS0A 2F29A 2IAWA 5M1ZA 2F24A 3WWAA 2XZKA 2DG0A 1E8TA 4GB1A 1OFZA 1C5KA 4GJTA 3L6VA 1DILA 4FPGA 4ZLRA 2QWDA 2HTRA 3UC1A 2GVWA 2IASA 2BERA 1V3EA 3GVJA 2VVZA 4XE9A 5NN9A 4NCSA 2IATA 4XJUA 4K1JA 2IAOA 3DASA 3S2KA 1N1TA 4D52A 1A4QA 2QWAA 1CVMA 2ZB5A 1EUTA 3NO0A 2CMLA 2QWEA 2A75A 1VCJA 2F26A 4ZGCA 3TI5A 4HW6A 4ZY3A 3SANA 5HUKA 1F8BA 5HUGA 1ZI0A 3FW0A 1NNAA 2W5NA 3GVKA 1Z4YA 4WA5A 1MWEA 2F28A 1NSCA 3NN9A 2VWDA 4M4VA 1MS5A 1MS9A 4FP2A 2QWIA 4AGTA 4D52C 2QWBA 1NMAN 4FP3A 2AEPA 3SRGA 2XZJA 3OPZA 3S94A 4XHBA 1W20A 2FPBA 3AMSA 2QWJA 4JF7A 4FPEA 4L7DA 4FPLA 5FNTA 1Z4VA 4NN9A 1QBIA 4XILA 3Q6PA 3G4HA 4XJ9A 1NSBA 4CH9A 5B2CA 4X6KA 1BJIA 2GHSA 2HT7A 5HUNA 1USXA 4BBWA 4MX0A 2W8BB 2SLIA 1N1YA 2YA8A 4GEZA 2SIMA 2F10A 1NMBN 3O9JA 1Z4ZA 3CYEA 4HZZA 5EO8A 4DGRA 1ZGKA 4KS4A 4WA4A 1RWIA 1V0EA 4HZWA 1L7FA 2VK7A 2YA6A 2XN4A 1V0ZA 1MS1A 3ALXA 3ADEA 3TI3A 5D9DA 2IAUA 4YZ3A 5FNRA 1N1VA 2FPCA 5F72C 4CPLA 1H6LA 6NN9A 1RWLA 1USRA 3Q6KA 4HHOA 1WCSA 1POOA 4XJQA 4HIZA 5F9TA 1IVFA 1NCBN 1N6EA 4XJAA 1V04A 1F8CA 4XJWA 2ISMA 3B7EA 1W8NA 3Q6TA 4YW1A 1IVEA 3ZGDA 5FZNA 4CPZA 4FPFA 1V3BA 4GZSA 2IVZA 1SO7A 1S18A 4YY8A 3SILA 1INGA 2IAPA 2ZW9A 3LI5A 1W0PA 4D4UA 2FP9A 1INFA 1IVBA 1S0JA 5FNSA 2GVVA 4QN5A 4CHBA 4B7MA 2BATA 1NCAN 1MZ5A 1MS3A 4FPJA 4WEFA 4GZPA 2B8HA 4WA3A 1SLLA 3V1SA 1INVA 4X4AA 1W8OA 4MWRA 2IAVA 4C1YA 3A9HA 4MWLA 3H72A 1PJXA 3HLHA 2WOZA 3SOBB 4G3NA 2FP8A 4XOGA 3HRPA 1MS8A 4D8SA 2XCYA 4IFJA 2HT5A 4DG6A 3H71A 4FOWA 4XJZA 1V3DA 1NN2A 4FQ4A 4GDJA 2HTVA 4KS1A 3INBA 3D12A 3T1EA 2SILA 2QWHA 4GZQA 4I00A 2G8SA 2VW2A 4M4NA 5D9CA 4X47A 1IVCA 4MZEA 3H73A 5JYYA 4L7BA 3PJQA 1C9UA 3K37A 2IAXA 1V2IA 2HU4A 4FOYA 5GX1A 2AH2A 3I1CA 4GN7A 2F12A 3BYCA 1SNTA 4MWYA 2HQSA 1S0IA 2QWCA 2DG1A 4CPNA 1QLGA 3U0SA 3K36A 4QN6A 1SUUA 2C4LA 4IQKA 4XMBA 4N1BA 4GNAA 3GVLA 4FJ6A 1L7HA 2X9MA 1B9SA 4GDIA 4O5TA 4XJ8A 5FNUA 1U6DX 5EO7A 2QWGA 1X2RA 3HLIA 4B7QA 4MJVA 4IFLX 1W21A 2VK5A 4J9TA 3ALWA 4HZYA 4MZAA 2RKCA 3K3AA 1IJQA 3S8VA 2W5OA 4M3MA 2HTWA 1NPEA 4XYXA 2BF6A 1IVDA 2P4OA 4XHXA 4WEGA 5GX3A 2DSOA 2ZWAA 3BEQA 1CRUA 1IUBA 3SALA 3AMRA 2ZZKA
chains in the Genus database with same CATH topology
4L7DA 5FNTA 5FNUA 1U6DX 2WOZA 2DYHA 4YY8A 1X2RA 2XN4A 3VNHA 4L7BA 4IFLX 3ADEA 3VNGA 4IFJA 4CH9A 2ZW9A 5FNRA 5CGJA 5F72C 2VPJA 4ZGCA 5FNSA 3ZGCA 4CHBA 4ZY3A 5FZJA 4L7CA 4IFNX 2Z32A 5FNQA 2ZWAA 2FLUX 4XMBA 4IQKA 4N1BA 3II7A 5FZNA 3WDZA 3WN7A 3ZGDA 4ASCA 1ZGKA 1X2JA 4IN4A 2ZZKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L7D A;  5FNT A;  5FNU A;  1U6D X;  2WOZ A;  2DYH A;  4YY8 A;  1X2R A;  2XN4 A;  3VNH A;  4L7B A;  4IFL X;  3ADE A;  3VNG A;  4IFJ A;  4CH9 A;  2ZW9 A;  5FNR A;  5CGJ A;  5F72 C;  2VPJ A;  4ZGC A;  5FNS A;  3ZGC A;  4CHB A;  4ZY3 A;  5FZJ A;  4L7C A;  4IFN X;  2Z32 A;  5FNQ A;  2ZWA A;  2FLU X;  4XMB A;  4IQK A;  4N1B A;  3II7 A;  5FZN A;  3WDZ A;  3WN7 A;  3ZGD A;  4ASC A;  1ZGK A;  1X2J A;  4IN4 A;  2ZZK A; 
#chains in the Genus database with same CATH topology
 4A0P A;  3KYA A;  4Q6K A;  3WW9 A;  4GN9 A;  3S8Z A;  3SOV A;  3VNG A;  2F27 A;  4H52 A;  4B7R A;  1V0F A;  1NCD N;  3TIB A;  4GN8 A;  4O5S A;  3DR2 A;  3KGG A;  3TC9 A;  1W1X A;  2VW1 A;  3ZGC A;  1IVG A;  1S1D A;  4MWX A;  5B2D A;  2HTY A;  3K39 A;  4UOU A;  4FPK A;  4X49 A;  3V65 B;  3JU4 A;  4CPY A;  4D52 B;  4B7J A;  1E1A A;  4YZ5 A;  4UF7 A;  5D9B A;  5GX5 A;  1SLI A;  4H53 A;  3P5B L;  5FWW A;  1K32 A;  1NNB A;  4XMA A;  1N6F A;  2YA4 A;  4YW2 A;  1NSD A;  3TI6 A;  1A14 N;  4MJU A;  2VW0 A;  2HT8 A;  2QWF A;  4IFN X;  4GZT A;  2W8B A;  3TI4 A;  4K1K A;  3WDZ A;  2F13 A;  4YZ2 A;  4XIO A;  3K38 A;  2BZD A;  1N7D A;  4KS5 A;  4MWJ A;  3G4E A;  5GX4 A;  4QN4 A;  4MWQ A;  3LI4 A;  4XJR A;  2AEQ A;  4XMI A;  3SRE A;  4B7N A;  4MC7 A;  4QNP A;  2VK6 A;  2HU0 A;  3TIC A;  1F8D A;  1INX A;  4IMB A;  4FPH A;  4AHA A;  4FVK A;  1EUU A;  4GZX A;  2F11 A;  3A71 A;  1DIM A;  4MWW A;  3CL2 A;  4KS3 A;  1W0O A;  4KS2 A;  4SLI A;  3CKZ A;  2POO A;  4FOQ A;  3FVZ A;  4YZ1 A;  2OJH A;  2QE8 A;  4IYG A;  1Z4X A;  4Q1U A;  3W09 A;  1WP5 A;  1CQ1 A;  4CSD A;  4HHQ A;  2YA5 A;  5H47 A;  1INY A;  2FLU X;  2XZI A;  1Z50 A;  1Q7F A;  3II7 A;  2JKB A;  1EUS A;  4MWV A;  4YZ4 A;  3A72 A;  3NSS A;  3A9G A;  4R40 A;  2W38 A;  2IAQ A;  4FOV A;  2IAR A;  2VSM A;  1XOE A;  4XIK A;  3IAX A;  4CPM A;  1V3C A;  4GZO A;  2VAQ A;  4K1H A;  4GZW A;  2QWK A;  4MWU A;  1L7G A;  1F8E A;  3B69 A;  2Z32 A;  1KIT A;  1NNC A;  4AGI A;  3LI3 A;  2F0Z A;  1A4G A;  1NCC N;  1X2J A;  4FPY A;  4IN4 A;  4FPO B;  1MS4 A;  4QN7 A;  4YW4 A;  4GNB A;  3VNH A;  5EX7 A;  4HZX A;  4YW5 A;  4FPC A;  2F25 A;  1NMC A;  3TIA A;  4CPO A;  4PWZ A;  5GX2 A;  2YDT A;  3D11 A;  2AGS A;  4NC5 A;  4QN3 A;  1EUR A;  5GTQ A;  2H2N A;  1INW A;  5FZJ A;  3SOQ A;  3CL0 A;  2FHR A;  2GVX A;  4HZV A;  2GVU A;  5HUM A;  3V64 C;  1VCU A;  4JML A;  4C1Y B;  4FZH A;  3SLI A;  3WN7 A;  3H6J A;  4K3Y A;  1IUC A;  1MR5 A;  5HX0 A;  4GNC A;  2HTU A;  3E5Z A;  3O4P A;  1CRZ A;  1E8U A;  2DYH A;  3TI8 A;  2VSK A;  2HTQ A;  4K1I A;  2W20 A;  2ZB6 A;  2YA7 A;  4AH4 A;  3O9K A;  5CGJ A;  4YW3 A;  4M4U A;  1B9V A;  1N6D A;  2H2U A;  1Z4W A;  2VPJ A;  1INH A;  2V91 A;  4L7C A;  2YDP A;  1WCQ A;  1E8V A;  5FNQ A;  1MZ6 A;  2C4A A;  1B9T A;  1N1S A;  4ASC A;  1XOG A;  7NN9 A;  1MS0 A;  2F29 A;  2IAW A;  5M1Z A;  2F24 A;  3WWA A;  2XZK A;  2DG0 A;  1E8T A;  4GB1 A;  1OFZ A;  1C5K A;  4GJT A;  3L6V A;  1DIL A;  4FPG A;  4ZLR A;  2QWD A;  2HTR A;  3UC1 A;  2GVW A;  2IAS A;  2BER A;  1V3E A;  3GVJ A;  2VVZ A;  4XE9 A;  5NN9 A;  4NCS A;  2IAT A;  4XJU A;  4K1J A;  2IAO A;  3DAS A;  3S2K A;  1N1T A;  4D52 A;  1A4Q A;  2QWA A;  1CVM A;  2ZB5 A;  1EUT A;  3NO0 A;  2CML A;  2QWE A;  2A75 A;  1VCJ A;  2F26 A;  4ZGC A;  3TI5 A;  4HW6 A;  4ZY3 A;  3SAN A;  5HUK A;  1F8B A;  5HUG A;  1ZI0 A;  3FW0 A;  1NNA A;  2W5N A;  3GVK A;  1Z4Y A;  4WA5 A;  1MWE A;  2F28 A;  1NSC A;  3NN9 A;  2VWD A;  4M4V A;  1MS5 A;  1MS9 A;  4FP2 A;  2QWI A;  4AGT A;  4D52 C;  2QWB A;  1NMA N;  4FP3 A;  2AEP A;  3SRG A;  2XZJ A;  3OPZ A;  3S94 A;  4XHB A;  1W20 A;  2FPB A;  3AMS A;  2QWJ A;  4JF7 A;  4FPE A;  4L7D A;  4FPL A;  5FNT A;  1Z4V A;  4NN9 A;  1QBI A;  4XIL A;  3Q6P A;  3G4H A;  4XJ9 A;  1NSB A;  4CH9 A;  5B2C A;  4X6K A;  1BJI A;  2GHS A;  2HT7 A;  5HUN A;  1USX A;  4BBW A;  4MX0 A;  2W8B B;  2SLI A;  1N1Y A;  2YA8 A;  4GEZ A;  2SIM A;  2F10 A;  1NMB N;  3O9J A;  1Z4Z A;  3CYE A;  4HZZ A;  5EO8 A;  4DGR A;  1ZGK A;  4KS4 A;  4WA4 A;  1RWI A;  1V0E A;  4HZW A;  1L7F A;  2VK7 A;  2YA6 A;  2XN4 A;  1V0Z A;  1MS1 A;  3ALX A;  3ADE A;  3TI3 A;  5D9D A;  2IAU A;  4YZ3 A;  5FNR A;  1N1V A;  2FPC A;  5F72 C;  4CPL A;  1H6L A;  6NN9 A;  1RWL A;  1USR A;  3Q6K A;  4HHO A;  1WCS A;  1POO A;  4XJQ A;  4HIZ A;  5F9T A;  1IVF A;  1NCB N;  1N6E A;  4XJA A;  1V04 A;  1F8C A;  4XJW A;  2ISM A;  3B7E A;  1W8N A;  3Q6T A;  4YW1 A;  1IVE A;  3ZGD A;  5FZN A;  4CPZ A;  4FPF A;  1V3B A;  4GZS A;  2IVZ A;  1SO7 A;  1S18 A;  4YY8 A;  3SIL A;  1ING A;  2IAP A;  2ZW9 A;  3LI5 A;  1W0P A;  4D4U A;  2FP9 A;  1INF A;  1IVB A;  1S0J A;  5FNS A;  2GVV A;  4QN5 A;  4CHB A;  4B7M A;  2BAT A;  1NCA N;  1MZ5 A;  1MS3 A;  4FPJ A;  4WEF A;  4GZP A;  2B8H A;  4WA3 A;  1SLL A;  3V1S A;  1INV A;  4X4A A;  1W8O A;  4MWR A;  2IAV A;  4C1Y A;  3A9H A;  4MWL A;  3H72 A;  1PJX A;  3HLH A;  2WOZ A;  3SOB B;  4G3N A;  2FP8 A;  4XOG A;  3HRP A;  1MS8 A;  4D8S A;  2XCY A;  4IFJ A;  2HT5 A;  4DG6 A;  3H71 A;  4FOW A;  4XJZ A;  1V3D A;  1NN2 A;  4FQ4 A;  4GDJ A;  2HTV A;  4KS1 A;  3INB A;  3D12 A;  3T1E A;  2SIL A;  2QWH A;  4GZQ A;  4I00 A;  2G8S A;  2VW2 A;  4M4N A;  5D9C A;  4X47 A;  1IVC A;  4MZE A;  3H73 A;  5JYY A;  4L7B A;  3PJQ A;  1C9U A;  3K37 A;  2IAX A;  1V2I A;  2HU4 A;  4FOY A;  5GX1 A;  2AH2 A;  3I1C A;  4GN7 A;  2F12 A;  3BYC A;  1SNT A;  4MWY A;  2HQS A;  1S0I A;  2QWC A;  2DG1 A;  4CPN A;  1QLG A;  3U0S A;  3K36 A;  4QN6 A;  1SUU A;  2C4L A;  4IQK A;  4XMB A;  4N1B A;  4GNA A;  3GVL A;  4FJ6 A;  1L7H A;  2X9M A;  1B9S A;  4GDI A;  4O5T A;  4XJ8 A;  5FNU A;  1U6D X;  5EO7 A;  2QWG A;  1X2R A;  3HLI A;  4B7Q A;  4MJV A;  4IFL X;  1W21 A;  2VK5 A;  4J9T A;  3ALW A;  4HZY A;  4MZA A;  2RKC A;  3K3A A;  1IJQ A;  3S8V A;  2W5O A;  4M3M A;  2HTW A;  1NPE A;  4XYX A;  2BF6 A;  1IVD A;  2P4O A;  4XHX A;  4WEG A;  5GX3 A;  2DSO A;  2ZWA A;  3BEQ A;  1CRU A;  1IUB A;  3SAL A;  3AMR A;  2ZZK A; 
#chains in the Genus database with same CATH homology
 4L7D A;  5FNT A;  5FNU A;  1U6D X;  2WOZ A;  2DYH A;  4YY8 A;  1X2R A;  2XN4 A;  3VNH A;  4L7B A;  4IFL X;  3ADE A;  3VNG A;  4IFJ A;  4CH9 A;  2ZW9 A;  5FNR A;  5CGJ A;  5F72 C;  2VPJ A;  4ZGC A;  5FNS A;  3ZGC A;  4CHB A;  4ZY3 A;  5FZJ A;  4L7C A;  4IFN X;  2Z32 A;  5FNQ A;  2ZWA A;  2FLU X;  4XMB A;  4IQK A;  4N1B A;  3II7 A;  5FZN A;  3WDZ A;  3WN7 A;  3ZGD A;  4ASC A;  1ZGK A;  1X2J A;  4IN4 A;  2ZZK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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