2F12A

Crystal structure of the human sialidase neu2 in complex with 3- hydroxypropyl ether mimetic inhibitor
Total Genus 95
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
375
structure length
359
Chain Sequence
SLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRAAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLNDRARSLVVPAYAYRKLHIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Human Sialidase Neu2 in Complex with 3- hydroxypropyl ether mimetic Inhibitor
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Sialidase 2
total genus 95
structure length 359
sequence length 375
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2005-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13088 BNR_2 BNR repeat-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 2f12A00
4BBWA 1INWA 1SNTA 2HT8A 1MS1A 1NSDA 2F12A 4CPLA 1WCSA 4QN4A 1EUTA 4XE9A 2VK6A 4K1HA 4D8SA 4YW5A 4WA5A 1N1YA 2YA5A 1W8OA 1SLLA 1MS9A 4NN9A 1S0IA 1B9SA 1VCJA 1N1VA 3O9JA 4XJRA 1MS5A 4NCSA 4XIOA 1A14N 1EURA 3CKZA 1INGA 3O9KA 3K36A 1INYA 4KS1A 4CPOA 3CYEA 2QWKA 4B7RA 3CL2A 2VSMA 4QNPA 1NNCA 1NMCA 4YZ3A 4YW1A 4K1IA 4XILA 4DGRA 2HT5A 1NMBN 4YZ5A 4HZVA 4I00A 4CPYA 4MJUA 3TI5A 4B7NA 4SLIA 1XOGA 2YA6A 1Z4WA 5HUNA 1W21A 2QWDA 4M4UA 3GVKA 4CPMA 2C4AA 3T1EA 1V0ZA 4XMIA 3NSSA 1E8TA 2VSKA 2F24A 3H71A 3D11A 5M1ZA 4K1KA 3TI6A 4FPCA 4FVKA 2VK7A 4FPEA 3W09A 2SLIA 4HIZA 2HU0A 4XJ9A 1F8BA 5B2CA 4GZXA 2YA4A 4XJWA 3BEQA 3B7EA 4GZOA 4FPJA 4HZXA 4XHXA 3ALXA 1Z4YA 2B8HA 2YA7A 1L7GA 4QN5A 1V2IA 4GJTA 1NCAN 1V3DA 4KS2A 4MWUA 3SALA 1NCDN 4WEFA 4FPKA 4MWQA 1IVFA 1INVA 1NNBA 1L7FA 1NCCN 4YW2A 2FHRA 1F8EA 1B9TA 2HTQA 1V3CA 2AH2A 4GB1A 2AEQA 3CL0A 2HTVA 4X4AA 3K38A 2CMLA 2XZIA 4MWRA 2BATA 4MJVA 3SANA 1USRA 2XZJA 4FOWA 5F9TA 1EUSA 4X49A 1KITA 3TICA 2W5OA 3INBA 3NN9A 4QN6A 2BF6A 2HTWA 3GVJA 2F0ZA 2ZB5A 1A4GA 1MS4A 4XJUA 4GZWA 4XYXA 5JYYA 1MZ5A 2A75A 4NC5A 4FP3A 4HZWA 1MS8A 2BZDA 4KS3A 4HZZA 2VW1A 1BJIA 1W20A 4GEZA 2AEPA 4KS5A 1XOEA 5HUKA 4FPYA 1W0PA 1IVGA 1NNAA 2QWEA 3H72A 4XHBA 4J9TA 1MS3A 1WCQA 2W38A 2SIMA 4M4NA 2F27A 4GDJA 2F25A 3TI3A 4M3MA 2YDPA 2BERA 4KS4A 2YA8A 4YW4A 4FJ6A 2HU4A 2F13A 2QWAA 4FP2A 2X9MA 2YDTA 1V0FA 2W5NA 4QN7A 3TI8A 4XJQA 3D12A 1Z4XA 4WA4A 2XCYA 1F8DA 4XMAA 4MZEA 2HTYA 2QWIA 4MWWA 4FOYA 1VCUA 1E8UA 3TIAA 4HZYA 1IVEA 2F26A 1DILA 2QWHA 1V0EA 1IVDA 1MR5A 1B9VA 1SLIA 1EUUA 1MWEA 4B7QA 4YZ4A 2HT7A 3H73A 5HX0A 1INFA 4XIKA 4CPZA 4H53A 4MWYA 2RKCA 4XOGA 6NN9A 4MWJA 5NN9A 2W20A 2HTRA 2SILA 1Z4ZA 3K39A 2HTUA 4YZ1A 4GZPA 4XJZA 1MS0A 2F10A 1N1TA 4YW3A 3H6JA 4XJ8A 1A4QA 3K37A 2C4LA 4H52A 3A71A 4FPHA 1USXA 1N1SA 4YZ2A 1INHA 2QWCA 1Z4VA 3K3AA 4MX0A 2VW0A 4Q6KA 4GDIA 2AGSA 4FPFA 1NSBA 1Z50A 1W0OA 2QWFA 4FOQA 4GZTA 7NN9A 1NMAN 4X47A 4K3YA 2F28A 2VVZA 2VW2A 4UF7A 3ALWA 1S0JA 4XJAA 4WA3A 4JF7A 2ZB6A 3GVLA 5B2DA 1INXA 3SILA 4GZSA 2VWDA 1L7HA 4CPNA 4M4VA 4MZAA 3SLIA 4X6KA 1SO7A 4QN3A 4FZHA 1NN2A 1IVCA 2XZKA 2QWGA 1E8VA 3TI4A 2VK5A 4WEGA 3OPZA 2QWJA 4FPGA 4MC7A 3TIBA 4FPOB 3JU4A 4MWLA 5HUMA 2JKBA 4B7MA 4FQ4A 2F29A 5HUGA 1V3BA 3B69A 1W8NA 4K1JA 3PJQA 1MZ6A 4FOVA 1F8CA 4B7JA 4FPLA 2F11A 1IVBA 4GZQA 1DIMA 4MWXA 1V3EA 4MWVA 1NSCA 2QWBA 1NCBN 3A72A 1W1XA
chains in the Genus database with same CATH superfamily
4BBWA 1INWA 1SNTA 2HT8A 1MS1A 1NSDA 2F12A 4CPLA 2IAWA 1WCSA 4QN4A 1EUTA 4XE9A 2VK6A 4K1HA 4D8SA 3IAXA 4YW5A 4WA5A 4CH9A 1N1YA 2YA5A 1W8OA 1SLLA 1MS9A 2IVZA 4NN9A 3O4PA 1S0IA 3L6VA 1B9SA 2DG1A 1VCJA 1N1VA 3O9JA 4XJRA 1RWLA 1MS5A 4NCSA 4XIOA 3V64C 5FNQA 1A14N 1EURA 3CKZA 1INGA 2DSOA 3O9KA 3HLIA 2IAPA 2IASA 1CRUA 3K36A 1INYA 4KS1A 4CPOA 3SRGA 3CYEA 1QLGA 2QWKA 4B7RA 1QBIA 1N6DA 3CL2A 2VSMA 4QNPA 1NNCA 1NMCA 4HW6A 4YZ3A 4K1IA 4IFJA 2W8BA 4XILA 4YW1A 4DGRA 4GNAA 2HT5A 1NMBN 4YZ5A 4HZVA 4I00A 4CPYA 4ZGCA 4MJUA 3TI5A 4B7NA 4SLIA 4DG6A 1XOGA 2YA6A 1Z4WA 5HUNA 1W21A 2FP9A 2QWDA 4M4UA 1CVMA 5GX4A 3GVKA 4R40A 4CPMA 2C4AA 3T1EA 1V0ZA 4XMIA 3NSSA 1E8TA 3AMSA 2VSKA 1IUCA 2F24A 3H71A 3D11A 5M1ZA 4D52C 4K1KA 3VNGA 3TI6A 1S1DA 4FPCA 4FVKA 2VK7A 1N6EA 4FPEA 5H47A 3W09A 5FNRA 2SLIA 4HIZA 5EO8A 2P4OA 2HU0A 2IAUA 4XJ9A 4IFLX 1F8BA 4ASCA 3KGGA 4CSDA 4ZY3A 5B2CA 3LI5A 4GZXA 5CGJA 2YA4A 4XJWA 2XN4A 3ADEA 3BEQA 3B7EA 4Q1UA 4GZOA 1CQ1A 3SREA 4FPJA 2H2NA 4C1YB 3KYAA 4HZXA 4XHXA 3ALXA 1Z4YA 2B8HA 2YA7A 1L7GA 4QN5A 1V2IA 4GJTA 1NCAN 1V3DA 4KS2A 4MWUA 3SALA 4GN9A 1NCDN 1U6DX 3G4HA 4HHQA 4WEFA 4FPKA 4ZLRA 4MWQA 5GTQA 1IVFA 1INVA 1NNBA 2FP8A 1L7FA 1NCCN 4YW2A 4GNCA 2FHRA 1F8EA 1B9TA 1S18A 2HTQA 1V04A 1V3CA 3SOBB 2AH2A 4GB1A 4IQKA 2AEQA 2ZW9A 1N7DA 3CL0A 3ZGCA 2HTVA 4X4AA 3DASA 3K38A 2CMLA 2XZIA 2GVWA 4D4UA 1C5KA 4MWRA 2BATA 4MJVA 3SANA 1USRA 2XZJA 4FOWA 5F9TA 4O5SA 1EUSA 4X49A 4D52B 1KITA 3TICA 2W5OA 3INBA 4GN7A 3NN9A 4QN6A 2BF6A 2HTWA 4YY8A 3GVJA 5D9BA 4PWZA 2F0ZA 2ZB5A 1A4GA 1MS4A 4XJUA 4N1BA 4GZWA 4XYXA 5JYYA 1MZ5A 5D9DA 5FNTA 2VPJA 2A75A 5FNSA 4NC5A 4FP3A 4HZWA 3V65B 4GNBA 1K32A 1MS8A 2BZDA 4KS3A 2FPBA 4HZZA 1NPEA 1BJIA 1W20A 2VW1A 4GEZA 2AEPA 4KS5A 3HRPA 1XOEA 4IFNX 5HUKA 2DG0A 4FPYA 1W0PA 1IVGA 2IATA 3WDZA 1NNAA 2QWEA 3H72A 3I1CA 4XHBA 2FPCA 2IAOA 4J9TA 5FWWA 1MS3A 1WCQA 2W38A 2SIMA 4M4NA 2F27A 4GDJA 2F25A 3TI3A 4M3MA 2YDPA 1N6FA 2WOZA 2BERA 4KS4A 1IJQA 3VNHA 2YA8A 2OJHA 2POOA 4YW4A 3SOVA 4FJ6A 3UC1A 5FNUA 5GX5A 2HU4A 2F13A 2QWAA 1E1AA 4FP2A 1SUUA 2GHSA 2X9MA 2YDTA 4IN4A 4AGTA 1V0FA 1POOA 2W5NA 4QN7A 3TI8A 2FLUX 4XJQA 2Z32A 3D12A 4O5TA 1Z4XA 4L7CA 3WW9A 4WA4A 2XCYA 1F8DA 4XMAA 4MZEA 2HTYA 2QWIA 4MWWA 4FOYA 1VCUA 1E8UA 3TC9A 3TIAA 4HZYA 2HQSA 1IVEA 2IAXA 2F26A 1C9UA 1DILA 3S8ZA 2QWHA 1V0EA 1IVDA 1MR5A 1B9VA 1SLIA 1Q7FA 1EUUA 1MWEA 4B7QA 4YZ4A 4JMLA 2GVVA 2HT7A 3H73A 1OFZA 4CHBA 5HX0A 1INFA 4XIKA 4CPZA 4H53A 4MWYA 2RKCA 2ZWAA 4XOGA 6NN9A 2GVUA 3S8VA 4MWJA 5NN9A 2W20A 2HTRA 2SILA 1RWIA 1Z4ZA 3K39A 2HTUA 4YZ1A 4GZPA 4XJZA 2G8SA 1X2RA 1MS0A 2F10A 1N1TA 5EX7A 4YW3A 3H6JA 4GN8A 4XJ8A 1A4QA 3K37A 1H6LA 2C4LA 3A9HA 4H52A 3A71A 5D9CA 4AHAA 4IYGA 4XMBA 4FPHA 1USXA 3S94A 1N1SA 4UOUA 4YZ2A 3LI4A 1INHA 4HHOA 3SOQA 3WN7A 2H2UA 2QWCA 1Z4VA 3Q6TA 1X2JA 5FZNA 2QE8A 3K3AA 4MX0A 2VW0A 4Q6KA 4GDIA 3AMRA 3NO0A 3HLHA 3Q6PA 2AGSA 2ZZKA 4FPFA 1NSBA 1WP5A 3U0SA 1Z50A 1W0OA 2QWFA 4FOQA 4GZTA 4G3NA 3E5ZA 3P5BL 1NMAN 4X47A 7NN9A 4K3YA 2F28A 2VVZA 2VW2A 4UF7A 3ALWA 1S0JA 4XJAA 3ZGDA 4WA3A 4JF7A 2ZB6A 3FVZA 3GVLA 1ZGKA 5B2DA 5GX2A 1INXA 3SILA 4IMBA 1CRZA 4GZSA 2VWDA 2DYHA 5EO7A 1PJXA 4AGIA 1L7HA 3A9GA 3Q6KA 4CPNA 2W8BB 4M4VA 4MZAA 3SLIA 4X6KA 1SO7A 4QN3A 1NN2A 1IVCA 4FZHA 2XZKA 2QWGA 3G4EA 5F72C 1E8VA 3TI4A 2VK5A 4WEGA 3WWAA 3OPZA 3II7A 5FZJA 2QWJA 4C1YA 4FPGA 4L7DA 4MC7A 2IAQA 3TIBA 4FPOB 3JU4A 4MWLA 3BYCA 3FW0A 5HUMA 2ISMA 2JKBA 4B7MA 4FQ4A 2F29A 5HUGA 2VAQA 1IUBA 3DR2A 4AH4A 2GVXA 1V3BA 3B69A 1W8NA 4K1JA 4L7BA 5GX3A 3V1SA 2IAVA 3PJQA 5GX1A 1MZ6A 4FOVA 3S2KA 1F8CA 4B7JA 4A0PA 4FPLA 2F11A 1ZI0A 2IARA 1IVBA 4GZQA 1DIMA 2V91A 3LI3A 4MWXA 1V3EA 4MWVA 1NSCA 2QWBA 1NCBN 3A72A 4D52A 1W1XA
chains in the Genus database with same CATH topology
4BBWA 1INWA 1SNTA 2HT8A 1MS1A 1NSDA 2F12A 4CPLA 1WCSA 4QN4A 1EUTA 4XE9A 2VK6A 4K1HA 4D8SA 4YW5A 4WA5A 1N1YA 2YA5A 1W8OA 1SLLA 1MS9A 4NN9A 1S0IA 1B9SA 1VCJA 1N1VA 3O9JA 4XJRA 1MS5A 4NCSA 4XIOA 1A14N 1EURA 3CKZA 1INGA 3O9KA 3K36A 1INYA 4KS1A 4CPOA 3CYEA 2QWKA 4B7RA 3CL2A 2VSMA 4QNPA 1NNCA 1NMCA 4YZ3A 4YW1A 4K1IA 4XILA 4DGRA 2HT5A 1NMBN 4YZ5A 4HZVA 4I00A 4CPYA 4MJUA 3TI5A 4B7NA 4SLIA 1XOGA 2YA6A 1Z4WA 5HUNA 1W21A 2QWDA 4M4UA 3GVKA 4CPMA 2C4AA 3T1EA 1V0ZA 4XMIA 3NSSA 1E8TA 2VSKA 2F24A 3H71A 3D11A 5M1ZA 4K1KA 3TI6A 1S1DA 4FPCA 4FVKA 2VK7A 4FPEA 3W09A 2SLIA 4HIZA 2HU0A 4XJ9A 1F8BA 5B2CA 4GZXA 2YA4A 4XJWA 3BEQA 3B7EA 4GZOA 4FPJA 2H2NA 4HZXA 4XHXA 3ALXA 1Z4YA 2B8HA 2YA7A 1L7GA 4QN5A 1V2IA 4GJTA 1NCAN 1V3DA 4KS2A 4MWUA 3SALA 1NCDN 4WEFA 4FPKA 4MWQA 1IVFA 1INVA 1NNBA 1L7FA 1NCCN 4YW2A 2FHRA 1F8EA 1B9TA 1S18A 2HTQA 1V3CA 2AH2A 4GB1A 2AEQA 3CL0A 2HTVA 4X4AA 3K38A 2CMLA 2XZIA 4MWRA 2BATA 4MJVA 3SANA 1USRA 2XZJA 4FOWA 5F9TA 1EUSA 4X49A 1KITA 3TICA 2W5OA 3INBA 3NN9A 4QN6A 2BF6A 2HTWA 3GVJA 2F0ZA 2ZB5A 1A4GA 1MS4A 4XJUA 4GZWA 4XYXA 5JYYA 1MZ5A 2A75A 4NC5A 4FP3A 4HZWA 1MS8A 2BZDA 4KS3A 4HZZA 2VW1A 1BJIA 1W20A 4GEZA 2AEPA 4KS5A 1XOEA 5HUKA 4FPYA 1W0PA 1IVGA 1NNAA 2QWEA 3H72A 4XHBA 4J9TA 1MS3A 1WCQA 2W38A 2SIMA 4M4NA 2F27A 4GDJA 2F25A 3TI3A 4M3MA 2YDPA 2BERA 4KS4A 2YA8A 4YW4A 4FJ6A 2HU4A 2F13A 2QWAA 4FP2A 2X9MA 2YDTA 1V0FA 2W5NA 4QN7A 3TI8A 4XJQA 3D12A 1Z4XA 4WA4A 2XCYA 1F8DA 4XMAA 4MZEA 2HTYA 2QWIA 4MWWA 4FOYA 1VCUA 1E8UA 3TIAA 4HZYA 1IVEA 2F26A 1DILA 2QWHA 1V0EA 1IVDA 1MR5A 1B9VA 1SLIA 1EUUA 1MWEA 4B7QA 4YZ4A 2HT7A 3H73A 5HX0A 1INFA 4XIKA 4CPZA 4H53A 4MWYA 2RKCA 4XOGA 6NN9A 4MWJA 5NN9A 2W20A 2HTRA 2SILA 1Z4ZA 3K39A 2HTUA 4YZ1A 4GZPA 4XJZA 1MS0A 2F10A 1N1TA 4YW3A 3H6JA 4XJ8A 1A4QA 3K37A 2C4LA 4H52A 3A71A 4FPHA 1USXA 1N1SA 4YZ2A 1INHA 2H2UA 2QWCA 1Z4VA 3K3AA 4MX0A 2VW0A 4Q6KA 4GDIA 2AGSA 4FPFA 1NSBA 1Z50A 1W0OA 2QWFA 4FOQA 4GZTA 7NN9A 1NMAN 4X47A 4K3YA 2F28A 2VVZA 2VW2A 4UF7A 3ALWA 1S0JA 4XJAA 4WA3A 4JF7A 2ZB6A 3GVLA 5B2DA 1INXA 3SILA 4GZSA 2VWDA 1L7HA 4CPNA 4M4VA 4MZAA 3SLIA 4X6KA 1SO7A 4QN3A 4FZHA 1NN2A 1IVCA 2XZKA 2QWGA 1E8VA 3TI4A 2VK5A 4WEGA 3OPZA 2QWJA 4FPGA 4MC7A 3TIBA 4FPOB 3JU4A 4MWLA 5HUMA 2JKBA 4B7MA 4FQ4A 2F29A 5HUGA 1V3BA 3B69A 1W8NA 4K1JA 3PJQA 1MZ6A 4FOVA 1F8CA 4B7JA 4FPLA 2F11A 1IVBA 4GZQA 1DIMA 4MWXA 1V3EA 4MWVA 1NSCA 2QWBA 1NCBN 3A72A 1W1XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BBW A;  1INW A;  1SNT A;  2HT8 A;  1MS1 A;  1NSD A;  2F12 A;  4CPL A;  1WCS A;  4QN4 A;  1EUT A;  4XE9 A;  2VK6 A;  4K1H A;  4D8S A;  4YW5 A;  4WA5 A;  1N1Y A;  2YA5 A;  1W8O A;  1SLL A;  1MS9 A;  4NN9 A;  1S0I A;  1B9S A;  1VCJ A;  1N1V A;  3O9J A;  4XJR A;  1MS5 A;  4NCS A;  4XIO A;  1A14 N;  1EUR A;  3CKZ A;  1ING A;  3O9K A;  3K36 A;  1INY A;  4KS1 A;  4CPO A;  3CYE A;  2QWK A;  4B7R A;  3CL2 A;  2VSM A;  4QNP A;  1NNC A;  1NMC A;  4YZ3 A;  4YW1 A;  4K1I A;  4XIL A;  4DGR A;  2HT5 A;  1NMB N;  4YZ5 A;  4HZV A;  4I00 A;  4CPY A;  4MJU A;  3TI5 A;  4B7N A;  4SLI A;  1XOG A;  2YA6 A;  1Z4W A;  5HUN A;  1W21 A;  2QWD A;  4M4U A;  3GVK A;  4CPM A;  2C4A A;  3T1E A;  1V0Z A;  4XMI A;  3NSS A;  1E8T A;  2VSK A;  2F24 A;  3H71 A;  3D11 A;  5M1Z A;  4K1K A;  3TI6 A;  4FPC A;  4FVK A;  2VK7 A;  4FPE A;  3W09 A;  2SLI A;  4HIZ A;  2HU0 A;  4XJ9 A;  1F8B A;  5B2C A;  4GZX A;  2YA4 A;  4XJW A;  3BEQ A;  3B7E A;  4GZO A;  4FPJ A;  4HZX A;  4XHX A;  3ALX A;  1Z4Y A;  2B8H A;  2YA7 A;  1L7G A;  4QN5 A;  1V2I A;  4GJT A;  1NCA N;  1V3D A;  4KS2 A;  4MWU A;  3SAL A;  1NCD N;  4WEF A;  4FPK A;  4MWQ A;  1IVF A;  1INV A;  1NNB A;  1L7F A;  1NCC N;  4YW2 A;  2FHR A;  1F8E A;  1B9T A;  2HTQ A;  1V3C A;  2AH2 A;  4GB1 A;  2AEQ A;  3CL0 A;  2HTV A;  4X4A A;  3K38 A;  2CML A;  2XZI A;  4MWR A;  2BAT A;  4MJV A;  3SAN A;  1USR A;  2XZJ A;  4FOW A;  5F9T A;  1EUS A;  4X49 A;  1KIT A;  3TIC A;  2W5O A;  3INB A;  3NN9 A;  4QN6 A;  2BF6 A;  2HTW A;  3GVJ A;  2F0Z A;  2ZB5 A;  1A4G A;  1MS4 A;  4XJU A;  4GZW A;  4XYX A;  5JYY A;  1MZ5 A;  2A75 A;  4NC5 A;  4FP3 A;  4HZW A;  1MS8 A;  2BZD A;  4KS3 A;  4HZZ A;  2VW1 A;  1BJI A;  1W20 A;  4GEZ A;  2AEP A;  4KS5 A;  1XOE A;  5HUK A;  4FPY A;  1W0P A;  1IVG A;  1NNA A;  2QWE A;  3H72 A;  4XHB A;  4J9T A;  1MS3 A;  1WCQ A;  2W38 A;  2SIM A;  4M4N A;  2F27 A;  4GDJ A;  2F25 A;  3TI3 A;  4M3M A;  2YDP A;  2BER A;  4KS4 A;  2YA8 A;  4YW4 A;  4FJ6 A;  2HU4 A;  2F13 A;  2QWA A;  4FP2 A;  2X9M A;  2YDT A;  1V0F A;  2W5N A;  4QN7 A;  3TI8 A;  4XJQ A;  3D12 A;  1Z4X A;  4WA4 A;  2XCY A;  1F8D A;  4XMA A;  4MZE A;  2HTY A;  2QWI A;  4MWW A;  4FOY A;  1VCU A;  1E8U A;  3TIA A;  4HZY A;  1IVE A;  2F26 A;  1DIL A;  2QWH A;  1V0E A;  1IVD A;  1MR5 A;  1B9V A;  1SLI A;  1EUU A;  1MWE A;  4B7Q A;  4YZ4 A;  2HT7 A;  3H73 A;  5HX0 A;  1INF A;  4XIK A;  4CPZ A;  4H53 A;  4MWY A;  2RKC A;  4XOG A;  6NN9 A;  4MWJ A;  5NN9 A;  2W20 A;  2HTR A;  2SIL A;  1Z4Z A;  3K39 A;  2HTU A;  4YZ1 A;  4GZP A;  4XJZ A;  1MS0 A;  2F10 A;  1N1T A;  4YW3 A;  3H6J A;  4XJ8 A;  1A4Q A;  3K37 A;  2C4L A;  4H52 A;  3A71 A;  4FPH A;  1USX A;  1N1S A;  4YZ2 A;  1INH A;  2QWC A;  1Z4V A;  3K3A A;  4MX0 A;  2VW0 A;  4Q6K A;  4GDI A;  2AGS A;  4FPF A;  1NSB A;  1Z50 A;  1W0O A;  2QWF A;  4FOQ A;  4GZT A;  7NN9 A;  1NMA N;  4X47 A;  4K3Y A;  2F28 A;  2VVZ A;  2VW2 A;  4UF7 A;  3ALW A;  1S0J A;  4XJA A;  4WA3 A;  4JF7 A;  2ZB6 A;  3GVL A;  5B2D A;  1INX A;  3SIL A;  4GZS A;  2VWD A;  1L7H A;  4CPN A;  4M4V A;  4MZA A;  3SLI A;  4X6K A;  1SO7 A;  4QN3 A;  4FZH A;  1NN2 A;  1IVC A;  2XZK A;  2QWG A;  1E8V A;  3TI4 A;  2VK5 A;  4WEG A;  3OPZ A;  2QWJ A;  4FPG A;  4MC7 A;  3TIB A;  4FPO B;  3JU4 A;  4MWL A;  5HUM A;  2JKB A;  4B7M A;  4FQ4 A;  2F29 A;  5HUG A;  1V3B A;  3B69 A;  1W8N A;  4K1J A;  3PJQ A;  1MZ6 A;  4FOV A;  1F8C A;  4B7J A;  4FPL A;  2F11 A;  1IVB A;  4GZQ A;  1DIM A;  4MWX A;  1V3E A;  4MWV A;  1NSC A;  2QWB A;  1NCB N;  3A72 A;  1W1X A; 
#chains in the Genus database with same CATH topology
 4BBW A;  1INW A;  1SNT A;  2HT8 A;  1MS1 A;  1NSD A;  2F12 A;  4CPL A;  2IAW A;  1WCS A;  4QN4 A;  1EUT A;  4XE9 A;  2VK6 A;  4K1H A;  4D8S A;  3IAX A;  4YW5 A;  4WA5 A;  4CH9 A;  1N1Y A;  2YA5 A;  1W8O A;  1SLL A;  1MS9 A;  2IVZ A;  4NN9 A;  3O4P A;  1S0I A;  3L6V A;  1B9S A;  2DG1 A;  1VCJ A;  1N1V A;  3O9J A;  4XJR A;  1RWL A;  1MS5 A;  4NCS A;  4XIO A;  3V64 C;  5FNQ A;  1A14 N;  1EUR A;  3CKZ A;  1ING A;  2DSO A;  3O9K A;  3HLI A;  2IAP A;  2IAS A;  1CRU A;  3K36 A;  1INY A;  4KS1 A;  4CPO A;  3SRG A;  3CYE A;  1QLG A;  2QWK A;  4B7R A;  1QBI A;  1N6D A;  3CL2 A;  2VSM A;  4QNP A;  1NNC A;  1NMC A;  4HW6 A;  4YZ3 A;  4K1I A;  4IFJ A;  2W8B A;  4XIL A;  4YW1 A;  4DGR A;  4GNA A;  2HT5 A;  1NMB N;  4YZ5 A;  4HZV A;  4I00 A;  4CPY A;  4ZGC A;  4MJU A;  3TI5 A;  4B7N A;  4SLI A;  4DG6 A;  1XOG A;  2YA6 A;  1Z4W A;  5HUN A;  1W21 A;  2FP9 A;  2QWD A;  4M4U A;  1CVM A;  5GX4 A;  3GVK A;  4R40 A;  4CPM A;  2C4A A;  3T1E A;  1V0Z A;  4XMI A;  3NSS A;  1E8T A;  3AMS A;  2VSK A;  1IUC A;  2F24 A;  3H71 A;  3D11 A;  5M1Z A;  4D52 C;  4K1K A;  3VNG A;  3TI6 A;  1S1D A;  4FPC A;  4FVK A;  2VK7 A;  1N6E A;  4FPE A;  5H47 A;  3W09 A;  5FNR A;  2SLI A;  4HIZ A;  5EO8 A;  2P4O A;  2HU0 A;  2IAU A;  4XJ9 A;  4IFL X;  1F8B A;  4ASC A;  3KGG A;  4CSD A;  4ZY3 A;  5B2C A;  3LI5 A;  4GZX A;  5CGJ A;  2YA4 A;  4XJW A;  2XN4 A;  3ADE A;  3BEQ A;  3B7E A;  4Q1U A;  4GZO A;  1CQ1 A;  3SRE A;  4FPJ A;  2H2N A;  4C1Y B;  3KYA A;  4HZX A;  4XHX A;  3ALX A;  1Z4Y A;  2B8H A;  2YA7 A;  1L7G A;  4QN5 A;  1V2I A;  4GJT A;  1NCA N;  1V3D A;  4KS2 A;  4MWU A;  3SAL A;  4GN9 A;  1NCD N;  1U6D X;  3G4H A;  4HHQ A;  4WEF A;  4FPK A;  4ZLR A;  4MWQ A;  5GTQ A;  1IVF A;  1INV A;  1NNB A;  2FP8 A;  1L7F A;  1NCC N;  4YW2 A;  4GNC A;  2FHR A;  1F8E A;  1B9T A;  1S18 A;  2HTQ A;  1V04 A;  1V3C A;  3SOB B;  2AH2 A;  4GB1 A;  4IQK A;  2AEQ A;  2ZW9 A;  1N7D A;  3CL0 A;  3ZGC A;  2HTV A;  4X4A A;  3DAS A;  3K38 A;  2CML A;  2XZI A;  2GVW A;  4D4U A;  1C5K A;  4MWR A;  2BAT A;  4MJV A;  3SAN A;  1USR A;  2XZJ A;  4FOW A;  5F9T A;  4O5S A;  1EUS A;  4X49 A;  4D52 B;  1KIT A;  3TIC A;  2W5O A;  3INB A;  4GN7 A;  3NN9 A;  4QN6 A;  2BF6 A;  2HTW A;  4YY8 A;  3GVJ A;  5D9B A;  4PWZ A;  2F0Z A;  2ZB5 A;  1A4G A;  1MS4 A;  4XJU A;  4N1B A;  4GZW A;  4XYX A;  5JYY A;  1MZ5 A;  5D9D A;  5FNT A;  2VPJ A;  2A75 A;  5FNS A;  4NC5 A;  4FP3 A;  4HZW A;  3V65 B;  4GNB A;  1K32 A;  1MS8 A;  2BZD A;  4KS3 A;  2FPB A;  4HZZ A;  1NPE A;  1BJI A;  1W20 A;  2VW1 A;  4GEZ A;  2AEP A;  4KS5 A;  3HRP A;  1XOE A;  4IFN X;  5HUK A;  2DG0 A;  4FPY A;  1W0P A;  1IVG A;  2IAT A;  3WDZ A;  1NNA A;  2QWE A;  3H72 A;  3I1C A;  4XHB A;  2FPC A;  2IAO A;  4J9T A;  5FWW A;  1MS3 A;  1WCQ A;  2W38 A;  2SIM A;  4M4N A;  2F27 A;  4GDJ A;  2F25 A;  3TI3 A;  4M3M A;  2YDP A;  1N6F A;  2WOZ A;  2BER A;  4KS4 A;  1IJQ A;  3VNH A;  2YA8 A;  2OJH A;  2POO A;  4YW4 A;  3SOV A;  4FJ6 A;  3UC1 A;  5FNU A;  5GX5 A;  2HU4 A;  2F13 A;  2QWA A;  1E1A A;  4FP2 A;  1SUU A;  2GHS A;  2X9M A;  2YDT A;  4IN4 A;  4AGT A;  1V0F A;  1POO A;  2W5N A;  4QN7 A;  3TI8 A;  2FLU X;  4XJQ A;  2Z32 A;  3D12 A;  4O5T A;  1Z4X A;  4L7C A;  3WW9 A;  4WA4 A;  2XCY A;  1F8D A;  4XMA A;  4MZE A;  2HTY A;  2QWI A;  4MWW A;  4FOY A;  1VCU A;  1E8U A;  3TC9 A;  3TIA A;  4HZY A;  2HQS A;  1IVE A;  2IAX A;  2F26 A;  1C9U A;  1DIL A;  3S8Z A;  2QWH A;  1V0E A;  1IVD A;  1MR5 A;  1B9V A;  1SLI A;  1Q7F A;  1EUU A;  1MWE A;  4B7Q A;  4YZ4 A;  4JML A;  2GVV A;  2HT7 A;  3H73 A;  1OFZ A;  4CHB A;  5HX0 A;  1INF A;  4XIK A;  4CPZ A;  4H53 A;  4MWY A;  2RKC A;  2ZWA A;  4XOG A;  6NN9 A;  2GVU A;  3S8V A;  4MWJ A;  5NN9 A;  2W20 A;  2HTR A;  2SIL A;  1RWI A;  1Z4Z A;  3K39 A;  2HTU A;  4YZ1 A;  4GZP A;  4XJZ A;  2G8S A;  1X2R A;  1MS0 A;  2F10 A;  1N1T A;  5EX7 A;  4YW3 A;  3H6J A;  4GN8 A;  4XJ8 A;  1A4Q A;  3K37 A;  1H6L A;  2C4L A;  3A9H A;  4H52 A;  3A71 A;  5D9C A;  4AHA A;  4IYG A;  4XMB A;  4FPH A;  1USX A;  3S94 A;  1N1S A;  4UOU A;  4YZ2 A;  3LI4 A;  1INH A;  4HHO A;  3SOQ A;  3WN7 A;  2H2U A;  2QWC A;  1Z4V A;  3Q6T A;  1X2J A;  5FZN A;  2QE8 A;  3K3A A;  4MX0 A;  2VW0 A;  4Q6K A;  4GDI A;  3AMR A;  3NO0 A;  3HLH A;  3Q6P A;  2AGS A;  2ZZK A;  4FPF A;  1NSB A;  1WP5 A;  3U0S A;  1Z50 A;  1W0O A;  2QWF A;  4FOQ A;  4GZT A;  4G3N A;  3E5Z A;  3P5B L;  1NMA N;  4X47 A;  7NN9 A;  4K3Y A;  2F28 A;  2VVZ A;  2VW2 A;  4UF7 A;  3ALW A;  1S0J A;  4XJA A;  3ZGD A;  4WA3 A;  4JF7 A;  2ZB6 A;  3FVZ A;  3GVL A;  1ZGK A;  5B2D A;  5GX2 A;  1INX A;  3SIL A;  4IMB A;  1CRZ A;  4GZS A;  2VWD A;  2DYH A;  5EO7 A;  1PJX A;  4AGI A;  1L7H A;  3A9G A;  3Q6K A;  4CPN A;  2W8B B;  4M4V A;  4MZA A;  3SLI A;  4X6K A;  1SO7 A;  4QN3 A;  1NN2 A;  1IVC A;  4FZH A;  2XZK A;  2QWG A;  3G4E A;  5F72 C;  1E8V A;  3TI4 A;  2VK5 A;  4WEG A;  3WWA A;  3OPZ A;  3II7 A;  5FZJ A;  2QWJ A;  4C1Y A;  4FPG A;  4L7D A;  4MC7 A;  2IAQ A;  3TIB A;  4FPO B;  3JU4 A;  4MWL A;  3BYC A;  3FW0 A;  5HUM A;  2ISM A;  2JKB A;  4B7M A;  4FQ4 A;  2F29 A;  5HUG A;  2VAQ A;  1IUB A;  3DR2 A;  4AH4 A;  2GVX A;  1V3B A;  3B69 A;  1W8N A;  4K1J A;  4L7B A;  5GX3 A;  3V1S A;  2IAV A;  3PJQ A;  5GX1 A;  1MZ6 A;  4FOV A;  3S2K A;  1F8C A;  4B7J A;  4A0P A;  4FPL A;  2F11 A;  1ZI0 A;  2IAR A;  1IVB A;  4GZQ A;  1DIM A;  2V91 A;  3LI3 A;  4MWX A;  1V3E A;  4MWV A;  1NSC A;  2QWB A;  1NCB N;  3A72 A;  4D52 A;  1W1X A; 
#chains in the Genus database with same CATH homology
 4BBW A;  1INW A;  1SNT A;  2HT8 A;  1MS1 A;  1NSD A;  2F12 A;  4CPL A;  1WCS A;  4QN4 A;  1EUT A;  4XE9 A;  2VK6 A;  4K1H A;  4D8S A;  4YW5 A;  4WA5 A;  1N1Y A;  2YA5 A;  1W8O A;  1SLL A;  1MS9 A;  4NN9 A;  1S0I A;  1B9S A;  1VCJ A;  1N1V A;  3O9J A;  4XJR A;  1MS5 A;  4NCS A;  4XIO A;  1A14 N;  1EUR A;  3CKZ A;  1ING A;  3O9K A;  3K36 A;  1INY A;  4KS1 A;  4CPO A;  3CYE A;  2QWK A;  4B7R A;  3CL2 A;  2VSM A;  4QNP A;  1NNC A;  1NMC A;  4YZ3 A;  4YW1 A;  4K1I A;  4XIL A;  4DGR A;  2HT5 A;  1NMB N;  4YZ5 A;  4HZV A;  4I00 A;  4CPY A;  4MJU A;  3TI5 A;  4B7N A;  4SLI A;  1XOG A;  2YA6 A;  1Z4W A;  5HUN A;  1W21 A;  2QWD A;  4M4U A;  3GVK A;  4CPM A;  2C4A A;  3T1E A;  1V0Z A;  4XMI A;  3NSS A;  1E8T A;  2VSK A;  2F24 A;  3H71 A;  3D11 A;  5M1Z A;  4K1K A;  3TI6 A;  1S1D A;  4FPC A;  4FVK A;  2VK7 A;  4FPE A;  3W09 A;  2SLI A;  4HIZ A;  2HU0 A;  4XJ9 A;  1F8B A;  5B2C A;  4GZX A;  2YA4 A;  4XJW A;  3BEQ A;  3B7E A;  4GZO A;  4FPJ A;  2H2N A;  4HZX A;  4XHX A;  3ALX A;  1Z4Y A;  2B8H A;  2YA7 A;  1L7G A;  4QN5 A;  1V2I A;  4GJT A;  1NCA N;  1V3D A;  4KS2 A;  4MWU A;  3SAL A;  1NCD N;  4WEF A;  4FPK A;  4MWQ A;  1IVF A;  1INV A;  1NNB A;  1L7F A;  1NCC N;  4YW2 A;  2FHR A;  1F8E A;  1B9T A;  1S18 A;  2HTQ A;  1V3C A;  2AH2 A;  4GB1 A;  2AEQ A;  3CL0 A;  2HTV A;  4X4A A;  3K38 A;  2CML A;  2XZI A;  4MWR A;  2BAT A;  4MJV A;  3SAN A;  1USR A;  2XZJ A;  4FOW A;  5F9T A;  1EUS A;  4X49 A;  1KIT A;  3TIC A;  2W5O A;  3INB A;  3NN9 A;  4QN6 A;  2BF6 A;  2HTW A;  3GVJ A;  2F0Z A;  2ZB5 A;  1A4G A;  1MS4 A;  4XJU A;  4GZW A;  4XYX A;  5JYY A;  1MZ5 A;  2A75 A;  4NC5 A;  4FP3 A;  4HZW A;  1MS8 A;  2BZD A;  4KS3 A;  4HZZ A;  2VW1 A;  1BJI A;  1W20 A;  4GEZ A;  2AEP A;  4KS5 A;  1XOE A;  5HUK A;  4FPY A;  1W0P A;  1IVG A;  1NNA A;  2QWE A;  3H72 A;  4XHB A;  4J9T A;  1MS3 A;  1WCQ A;  2W38 A;  2SIM A;  4M4N A;  2F27 A;  4GDJ A;  2F25 A;  3TI3 A;  4M3M A;  2YDP A;  2BER A;  4KS4 A;  2YA8 A;  4YW4 A;  4FJ6 A;  2HU4 A;  2F13 A;  2QWA A;  4FP2 A;  2X9M A;  2YDT A;  1V0F A;  2W5N A;  4QN7 A;  3TI8 A;  4XJQ A;  3D12 A;  1Z4X A;  4WA4 A;  2XCY A;  1F8D A;  4XMA A;  4MZE A;  2HTY A;  2QWI A;  4MWW A;  4FOY A;  1VCU A;  1E8U A;  3TIA A;  4HZY A;  1IVE A;  2F26 A;  1DIL A;  2QWH A;  1V0E A;  1IVD A;  1MR5 A;  1B9V A;  1SLI A;  1EUU A;  1MWE A;  4B7Q A;  4YZ4 A;  2HT7 A;  3H73 A;  5HX0 A;  1INF A;  4XIK A;  4CPZ A;  4H53 A;  4MWY A;  2RKC A;  4XOG A;  6NN9 A;  4MWJ A;  5NN9 A;  2W20 A;  2HTR A;  2SIL A;  1Z4Z A;  3K39 A;  2HTU A;  4YZ1 A;  4GZP A;  4XJZ A;  1MS0 A;  2F10 A;  1N1T A;  4YW3 A;  3H6J A;  4XJ8 A;  1A4Q A;  3K37 A;  2C4L A;  4H52 A;  3A71 A;  4FPH A;  1USX A;  1N1S A;  4YZ2 A;  1INH A;  2H2U A;  2QWC A;  1Z4V A;  3K3A A;  4MX0 A;  2VW0 A;  4Q6K A;  4GDI A;  2AGS A;  4FPF A;  1NSB A;  1Z50 A;  1W0O A;  2QWF A;  4FOQ A;  4GZT A;  7NN9 A;  1NMA N;  4X47 A;  4K3Y A;  2F28 A;  2VVZ A;  2VW2 A;  4UF7 A;  3ALW A;  1S0J A;  4XJA A;  4WA3 A;  4JF7 A;  2ZB6 A;  3GVL A;  5B2D A;  1INX A;  3SIL A;  4GZS A;  2VWD A;  1L7H A;  4CPN A;  4M4V A;  4MZA A;  3SLI A;  4X6K A;  1SO7 A;  4QN3 A;  4FZH A;  1NN2 A;  1IVC A;  2XZK A;  2QWG A;  1E8V A;  3TI4 A;  2VK5 A;  4WEG A;  3OPZ A;  2QWJ A;  4FPG A;  4MC7 A;  3TIB A;  4FPO B;  3JU4 A;  4MWL A;  5HUM A;  2JKB A;  4B7M A;  4FQ4 A;  2F29 A;  5HUG A;  1V3B A;  3B69 A;  1W8N A;  4K1J A;  3PJQ A;  1MZ6 A;  4FOV A;  1F8C A;  4B7J A;  4FPL A;  2F11 A;  1IVB A;  4GZQ A;  1DIM A;  4MWX A;  1V3E A;  4MWV A;  1NSC A;  2QWB A;  1NCB N;  3A72 A;  1W1X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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