2F25A

Crystal structure of the human sialidase neu2 e111q mutant in complex with dana inhibitor
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
377
structure length
373
Chain Sequence
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTQQQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLNDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Human Sialidase Neu2 E111Q Mutant in Complex with DANA Inhibitor
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Sialidase 2
total genus 101
structure length 373
sequence length 377
chains with identical sequence B
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2005-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13088 BNR_2 BNR repeat-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 2f25A00
4WA5A 4GZPA 4GZOA 1NCAN 1USXA 4I00A 1IVEA 2YDTA 4K1JA 2HTQA 3OPZA 1XOGA 2SILA 4JF7A 1F8CA 1NSBA 3SLIA 4GZTA 3ALWA 4YW1A 4MZEA 4D8SA 2HT7A 1INVA 1Z50A 4HZYA 2F10A 1Z4WA 1WCSA 4XJ9A 4MJVA 4XJAA 4FPFA 4GEZA 3TI8A 5HUKA 2F0ZA 2XZKA 4GB1A 1Z4VA 2B8HA 3B69A 4KS5A 4CPNA 2HU0A 3O9KA 5HUMA 1W1XA 4YZ3A 3A71A 4QNPA 3BEQA 4CPLA 1NSCA 1V3EA 4XILA 1IVDA 2A75A 1V0EA 4HZWA 2HTYA 2VW0A 4MWVA 1B9SA 1W8NA 2QWIA 4FPCA 4X47A 4CPYA 1NMCA 3TI6A 1W20A 2F12A 2F11A 1MZ6A 1NNBA 4GDIA 4KS1A 2VVZA 3GVKA 4YZ4A 4UF7A 3GVJA 4NN9A 2ZB6A 2C4AA 1F8EA 4FPLA 6NN9A 2VWDA 1SNTA 4X6KA 4CPMA 1Z4XA 4M4VA 2HT5A 2HTUA 3PJQA 4GZSA 2JKBA 3CYEA 4HZVA 2QWJA 4QN6A 1MS8A 3SANA 3CL0A 4XOGA 4FPOB 4FPEA 4FPGA 2W38A 3NN9A 4YW3A 2F24A 1B9VA 2X9MA 2HTRA 4XJZA 5HUGA 4XE9A 1BJIA 2F28A 1A14N 1EUUA 1V3CA 5NN9A 3TI5A 2VSKA 4XJQA 1IVGA 1W0PA 3K37A 4B7QA 4QN3A 4MWWA 1F8BA 3D11A 4MWXA 1DILA 3W09A 4YZ2A 2AEPA 2AGSA 2QWGA 1NCDN 4MWQA 3TIBA 3INBA 2VK6A 4H52A 4KS3A 2XZJA 4CPZA 4MWYA 3TIAA 2BERA 4GZXA 4QN5A 2YA6A 4XJUA 3SILA 2F26A 2YA4A 2BF6A 5M1ZA 1MS9A 4B7MA 3SALA 4K1IA 2YDPA 1NMAN 2QWHA 4BBWA 1MS1A 2RKCA 1NN2A 1V0FA 4XYXA 1INXA 2HTVA 2SIMA 4FPHA 2AH2A 1L7HA 4GDJA 4FP3A 1NNCA 1Z4YA 2F29A 4MZAA 4QN4A 3A72A 4KS4A 4GZQA 4B7RA 3TI3A 4FJ6A 4GZWA 4XJ8A 4MWLA 2YA5A 4CPOA 4B7NA 4GJTA 4FVKA 1MS0A 1V3BA 2HT8A 1IVFA 2VW1A 1L7FA 2W20A 2ZB5A 1EUTA 2VK7A 1NCBN 1N1TA 2QWKA 4YW4A 4XHXA 1N1VA 2QWBA 1EUSA 1W21A 1Z4ZA 4FQ4A 4XHBA 4X49A 1KITA 3K3AA 1INYA 5B2DA 4FPKA 1W0OA 2BATA 1VCJA 2QWAA 3GVLA 2QWFA 2VW2A 4MC7A 3TI4A 4HIZA 4MX0A 1S0IA 2F25A 4B7JA 1NCCN 3CKZA 4MWUA 4XJRA 1V3DA 4FOWA 4WEFA 3K36A 1SO7A 2QWCA 5HUNA 2HTWA 1N1YA 5B2CA 2C4LA 4FOVA 3D12A 1EURA 1WCQA 2CMLA 4K3YA 1SLIA 2YA8A 4YZ1A 1VCUA 2AEQA 4M4NA 2XZIA 4SLIA 4MJUA 2VK5A 4XIKA 1F8DA 4MWJA 2F27A 1V0ZA 1E8UA 3H73A 1NSDA 4J9TA 1IVCA 1INGA 1MS5A 4FZHA 7NN9A 3ALXA 1INHA 1W8OA 4FOYA 2W5NA 1A4GA 1V2IA 1MR5A 2HU4A 1MS4A 4WA3A 1IVBA 4XJWA 4XMAA 3H6JA 1E8VA 1MS3A 4WA4A 2XCYA 3NSSA 1SLLA 4M3MA 4FOQA 4HZXA 3H71A 4K1KA 3B7EA 4XIOA 4MWRA 1NMBN 2SLIA 1INWA 4NC5A 4QN7A 4YZ5A 4FPJA 1MZ5A 1N1SA 5F9TA 3T1EA 4DGRA 4X4AA 2VSMA 5HX0A 4YW2A 1B9TA 2QWDA 4Q6KA 3TICA 1S0JA 5JYYA 4H53A 3JU4A 3K38A 4M4UA 4NCSA 2BZDA 4WEGA 4FPYA 1A4QA 2QWEA 3CL2A 2YA7A 3H72A 4FP2A 4KS2A 1NNAA 4K1HA 1INFA 1L7GA 3K39A 2W5OA 1XOEA 4YW5A 4HZZA 1USRA 1DIMA 2F13A 4XMIA 3O9JA 1E8TA 2FHRA 1MWEA
chains in the Genus database with same CATH superfamily
4WA5A 5FZNA 4GZPA 4IFJA 4O5TA 3P5BL 4GZOA 1NCAN 2FPBA 1USXA 3VNHA 4I00A 2Z32A 1S1DA 1IVEA 2YDTA 4K1JA 4ASCA 2HTQA 3OPZA 2ZZKA 1XOGA 2SILA 4JF7A 1F8CA 1NPEA 1NSBA 2ISMA 3SLIA 1POOA 3G4EA 1PJXA 2IAVA 4GZTA 3ALWA 4L7BA 4YW1A 4N1BA 4MZEA 4D8SA 2HT7A 1INVA 1Z50A 4HZYA 1N6EA 1E1AA 2F10A 1WP5A 1Z4WA 4CH9A 1N6FA 1ZI0A 4G3NA 1WCSA 1QBIA 4XJ9A 2VAQA 4MJVA 4XJAA 4FPFA 3TC9A 4GEZA 3TI8A 5HUKA 2F0ZA 2XZKA 4GB1A 1Z4VA 2B8HA 3A9HA 3B69A 4KS5A 4CPNA 2HU0A 3O9KA 5HUMA 1W1XA 2OJHA 4YZ3A 2DG0A 3A71A 2IAUA 3Q6KA 4QNPA 4D4UA 2WOZA 3BEQA 4CPLA 1NSCA 3AMRA 1V3EA 4XILA 1IVDA 4A0PA 2DG1A 2A75A 2GVWA 1V0EA 4HZWA 2HTYA 5F72C 1QLGA 2VW0A 3NO0A 4MWVA 4IN4A 4AHAA 1B9SA 1W8NA 2QWIA 4FPCA 4X47A 4AH4A 4CPYA 3ZGDA 1NMCA 1CRZA 3LI5A 1IUCA 3TI6A 3U0SA 1W20A 2F12A 2F11A 4C1YA 1MZ6A 1NNBA 4GDIA 4KS1A 2VVZA 3KYAA 3GVKA 4YZ4A 3V65B 4UF7A 3GVJA 4NN9A 2ZB6A 2C4AA 1F8EA 4FPLA 6NN9A 2VWDA 4GNBA 4GN9A 1SNTA 4X6KA 4CPMA 2QE8A 1Z4XA 3SOVA 2FPCA 4ZGCA 4M4VA 2HQSA 2HT5A 2HTUA 2IATA 4AGIA 3PJQA 4GZSA 2JKBA 3CYEA 2GVXA 4HZVA 3O4PA 2QWJA 4QN6A 1MS8A 3A9GA 3SANA 3CL0A 4XOGA 4FPOB 4L7DA 2GHSA 4FPEA 4FPGA 4Q1UA 2W38A 3NN9A 1H6LA 4YW3A 3S94A 2F24A 1B9VA 4IFLX 2X9MA 2HTRA 4XJZA 5HUGA 4XE9A 1BJIA 2F28A 4C1YB 1A14N 5D9DA 4O5SA 1EUUA 1V3CA 5GX1A 5NN9A 3TI5A 2VSKA 4XJQA 1IVGA 1W0PA 3K37A 4B7QA 4CHBA 3SOQA 4QN3A 4MWWA 1F8BA 3D11A 4MWXA 1DILA 3S2KA 3W09A 1OFZA 4YZ2A 2AEPA 2AGSA 3HRPA 2QWGA 3KGGA 1NCDN 4AGTA 4MWQA 3TIBA 1ZGKA 3INBA 2VK6A 1C5KA 4H52A 3WW9A 4KS3A 5FZJA 2H2UA 2FLUX 2XZJA 4CPZA 4MWYA 3TIAA 2W8BA 2FP8A 2BERA 2IAXA 4GZXA 4QN5A 5GX4A 2YA6A 4XJUA 2GVUA 1S18A 5GTQA 3SILA 2F26A 2YA4A 2BF6A 5M1ZA 1MS9A 4B7MA 3SALA 4K1IA 1K32A 2YDPA 1NMAN 2QWHA 4IQKA 3HLHA 4UOUA 4BBWA 3V1SA 1MS1A 2RKCA 4GNAA 4GNCA 1NN2A 1V0FA 3ZGCA 4XYXA 1INXA 2HTVA 2SIMA 4FPHA 2AH2A 1L7HA 2G8SA 2IAQA 4GDJA 4FP3A 2IAOA 1NNCA 1X2RA 2ZW9A 4YY8A 1Z4YA 4ZY3A 2F29A 3DASA 3LI4A 3WDZA 4D52A 3G4HA 5GX2A 4MZAA 4QN4A 5GX5A 3A72A 4KS4A 4GZQA 4B7RA 4JMLA 3TI3A 4FJ6A 4GZWA 4XJ8A 4MWLA 2YA5A 4CPOA 4B7NA 3VNGA 4GJTA 4FVKA 2W8BB 4HHOA 1MS0A 1V3BA 2HT8A 1IVFA 2VW1A 1L7FA 2W20A 5EX7A 2ZB5A 3S8VA 1IUBA 1EUTA 1N6DA 2VK7A 2FP9A 1NCBN 1N1TA 2QWKA 4XMBA 4YW4A 2ZWAA 4XHXA 1N1VA 3II7A 2IASA 3SOBB 2QWBA 5EO7A 4CSDA 1C9UA 1EUSA 1W21A 1Z4ZA 4FQ4A 4XHBA 4X49A 1KITA 3SRGA 3K3AA 1INYA 4D52B 5B2DA 4FPKA 1W0OA 2BATA 1VCJA 2QWAA 2IAPA 4R40A 3GVLA 4IYGA 4HW6A 2QWFA 1CRUA 2VW2A 5H47A 4MC7A 3TI4A 4HIZA 4MX0A 2DSOA 1S0IA 2F25A 4B7JA 1NCCN 3CKZA 4MWUA 4XJRA 1V3DA 4FOWA 5FNUA 5GX3A 4WEFA 1IJQA 1Q7FA 3K36A 4PWZA 1SO7A 2QWCA 5HUNA 2HTWA 1N1YA 5B2CA 2IAWA 2C4LA 4FOVA 3E5ZA 3D12A 1EURA 1WCQA 2CMLA 4K3YA 4DG6A 1SLIA 2YA8A 4YZ1A 3Q6PA 1VCUA 2AEQA 4M4NA 3UC1A 2XZIA 2V91A 4SLIA 2GVVA 1RWIA 1V04A 4MJUA 1U6DX 2IARA 2VK5A 3LI3A 4XIKA 1F8DA 5FNSA 4MWJA 2F27A 1V0ZA 1E8UA 3H73A 1NSDA 2P4OA 1IVCA 4J9TA 4L7CA 3WWAA 1INGA 5EO8A 1MS5A 4FZHA 7NN9A 3ALXA 1INHA 5FWWA 1W8OA 4FOYA 3AMSA 2W5NA 3SREA 1A4GA 4IMBA 1V2IA 1MR5A 1X2JA 2HU4A 1MS4A 3L6VA 3HLIA 4WA3A 1IVBA 4XJWA 4XMAA 3H6JA 3I1CA 1E8VA 1MS3A 3WN7A 4WA4A 2XCYA 2XN4A 3NSSA 1SLLA 1N7DA 2H2NA 4M3MA 4FOQA 4HZXA 3IAXA 3H71A 3V64C 4K1KA 3B7EA 5FNTA 5D9CA 4XIOA 4MWRA 1NMBN 2SLIA 1INWA 4NC5A 1RWLA 4QN7A 4YZ5A 5FNRA 4FPJA 1MZ5A 1CQ1A 1N1SA 5F9TA 3T1EA 4DGRA 4X4AA 4ZLRA 2VSMA 5HX0A 4YW2A 1B9TA 2QWDA 4Q6KA 3FVZA 3TICA 1S0JA 5JYYA 4H53A 3JU4A 3K38A 3Q6TA 4M4UA 2BZDA 4NCSA 4WEGA 5D9BA 2VPJA 4FPYA 4GN7A 4IFNX 3BYCA 1A4QA 2QWEA 3CL2A 2YA7A 3S8ZA 2POOA 3H72A 4FP2A 1SUUA 4KS2A 4HHQA 1NNAA 5CGJA 4K1HA 1INFA 5FNQA 1L7GA 3K39A 2W5OA 1XOEA 4YW5A 4HZZA 4GN8A 1USRA 2DYHA 4D52C 3DR2A 1DIMA 1CVMA 2F13A 3FW0A 2IVZA 3ADEA 4XMIA 3O9JA 1E8TA 2FHRA 1MWEA
chains in the Genus database with same CATH topology
4WA5A 4GZPA 4GZOA 1NCAN 1USXA 4I00A 1S1DA 1IVEA 2YDTA 4K1JA 2HTQA 3OPZA 1XOGA 2SILA 4JF7A 1F8CA 1NSBA 3SLIA 4GZTA 3ALWA 4YW1A 4MZEA 4D8SA 2HT7A 1INVA 1Z50A 4HZYA 2F10A 1Z4WA 1WCSA 4XJ9A 4MJVA 4XJAA 4FPFA 4GEZA 3TI8A 5HUKA 2F0ZA 2XZKA 4GB1A 1Z4VA 2B8HA 3B69A 4KS5A 4CPNA 2HU0A 3O9KA 5HUMA 1W1XA 4YZ3A 3A71A 4QNPA 3BEQA 4CPLA 1NSCA 1V3EA 4XILA 1IVDA 2A75A 1V0EA 4HZWA 2HTYA 2VW0A 4MWVA 1B9SA 1W8NA 2QWIA 4FPCA 4X47A 4CPYA 1NMCA 3TI6A 1W20A 2F12A 2F11A 1MZ6A 1NNBA 4GDIA 4KS1A 2VVZA 3GVKA 4YZ4A 4UF7A 3GVJA 4NN9A 2ZB6A 2C4AA 1F8EA 4FPLA 6NN9A 2VWDA 1SNTA 4X6KA 4CPMA 1Z4XA 4M4VA 2HT5A 2HTUA 3PJQA 4GZSA 2JKBA 3CYEA 4HZVA 2QWJA 4QN6A 1MS8A 3SANA 3CL0A 4XOGA 4FPOB 4FPEA 4FPGA 2W38A 3NN9A 4YW3A 2F24A 1B9VA 2X9MA 2HTRA 4XJZA 5HUGA 4XE9A 1BJIA 2F28A 1A14N 1EUUA 1V3CA 5NN9A 3TI5A 2VSKA 4XJQA 1IVGA 1W0PA 3K37A 4B7QA 4QN3A 4MWWA 1F8BA 3D11A 4MWXA 1DILA 3W09A 4YZ2A 2AEPA 2AGSA 2QWGA 1NCDN 4MWQA 3TIBA 3INBA 2VK6A 4H52A 4KS3A 2H2UA 2XZJA 4CPZA 4MWYA 3TIAA 2BERA 4GZXA 4QN5A 2YA6A 4XJUA 1S18A 3SILA 2F26A 2YA4A 2BF6A 5M1ZA 1MS9A 4B7MA 3SALA 4K1IA 2YDPA 1NMAN 2QWHA 4BBWA 1MS1A 2RKCA 1NN2A 1V0FA 4XYXA 1INXA 2HTVA 2SIMA 4FPHA 2AH2A 1L7HA 4GDJA 4FP3A 1NNCA 1Z4YA 2F29A 4MZAA 4QN4A 3A72A 4KS4A 4GZQA 4B7RA 3TI3A 4FJ6A 4GZWA 4XJ8A 4MWLA 2YA5A 4CPOA 4B7NA 4GJTA 4FVKA 1MS0A 1V3BA 2HT8A 1IVFA 2VW1A 1L7FA 2W20A 2ZB5A 1EUTA 2VK7A 1NCBN 1N1TA 2QWKA 4YW4A 4XHXA 1N1VA 2QWBA 1EUSA 1W21A 1Z4ZA 4FQ4A 4XHBA 4X49A 1KITA 3K3AA 1INYA 5B2DA 4FPKA 1W0OA 2BATA 1VCJA 2QWAA 3GVLA 2QWFA 2VW2A 4MC7A 3TI4A 4HIZA 4MX0A 1S0IA 2F25A 4B7JA 1NCCN 3CKZA 4MWUA 4XJRA 1V3DA 4FOWA 4WEFA 3K36A 1SO7A 2QWCA 5HUNA 2HTWA 1N1YA 5B2CA 2C4LA 4FOVA 3D12A 1EURA 1WCQA 2CMLA 4K3YA 1SLIA 2YA8A 4YZ1A 1VCUA 2AEQA 4M4NA 2XZIA 4SLIA 4MJUA 2VK5A 4XIKA 1F8DA 4MWJA 2F27A 1V0ZA 1E8UA 3H73A 1NSDA 4J9TA 1IVCA 1INGA 1MS5A 4FZHA 7NN9A 3ALXA 1INHA 1W8OA 4FOYA 2W5NA 1A4GA 1V2IA 1MR5A 2HU4A 1MS4A 4WA3A 1IVBA 4XJWA 4XMAA 3H6JA 1E8VA 1MS3A 4WA4A 2XCYA 3NSSA 1SLLA 2H2NA 4M3MA 4FOQA 4HZXA 3H71A 4K1KA 3B7EA 4XIOA 4MWRA 1NMBN 2SLIA 1INWA 4NC5A 4QN7A 4YZ5A 4FPJA 1MZ5A 1N1SA 5F9TA 3T1EA 4DGRA 4X4AA 2VSMA 5HX0A 4YW2A 1B9TA 2QWDA 4Q6KA 3TICA 1S0JA 5JYYA 4H53A 3JU4A 3K38A 4M4UA 4NCSA 2BZDA 4WEGA 4FPYA 1A4QA 2QWEA 3CL2A 2YA7A 3H72A 4FP2A 4KS2A 1NNAA 4K1HA 1INFA 1L7GA 3K39A 2W5OA 1XOEA 4YW5A 4HZZA 1USRA 1DIMA 2F13A 4XMIA 3O9JA 1E8TA 2FHRA 1MWEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WA5 A;  4GZP A;  4GZO A;  1NCA N;  1USX A;  4I00 A;  1IVE A;  2YDT A;  4K1J A;  2HTQ A;  3OPZ A;  1XOG A;  2SIL A;  4JF7 A;  1F8C A;  1NSB A;  3SLI A;  4GZT A;  3ALW A;  4YW1 A;  4MZE A;  4D8S A;  2HT7 A;  1INV A;  1Z50 A;  4HZY A;  2F10 A;  1Z4W A;  1WCS A;  4XJ9 A;  4MJV A;  4XJA A;  4FPF A;  4GEZ A;  3TI8 A;  5HUK A;  2F0Z A;  2XZK A;  4GB1 A;  1Z4V A;  2B8H A;  3B69 A;  4KS5 A;  4CPN A;  2HU0 A;  3O9K A;  5HUM A;  1W1X A;  4YZ3 A;  3A71 A;  4QNP A;  3BEQ A;  4CPL A;  1NSC A;  1V3E A;  4XIL A;  1IVD A;  2A75 A;  1V0E A;  4HZW A;  2HTY A;  2VW0 A;  4MWV A;  1B9S A;  1W8N A;  2QWI A;  4FPC A;  4X47 A;  4CPY A;  1NMC A;  3TI6 A;  1W20 A;  2F12 A;  2F11 A;  1MZ6 A;  1NNB A;  4GDI A;  4KS1 A;  2VVZ A;  3GVK A;  4YZ4 A;  4UF7 A;  3GVJ A;  4NN9 A;  2ZB6 A;  2C4A A;  1F8E A;  4FPL A;  6NN9 A;  2VWD A;  1SNT A;  4X6K A;  4CPM A;  1Z4X A;  4M4V A;  2HT5 A;  2HTU A;  3PJQ A;  4GZS A;  2JKB A;  3CYE A;  4HZV A;  2QWJ A;  4QN6 A;  1MS8 A;  3SAN A;  3CL0 A;  4XOG A;  4FPO B;  4FPE A;  4FPG A;  2W38 A;  3NN9 A;  4YW3 A;  2F24 A;  1B9V A;  2X9M A;  2HTR A;  4XJZ A;  5HUG A;  4XE9 A;  1BJI A;  2F28 A;  1A14 N;  1EUU A;  1V3C A;  5NN9 A;  3TI5 A;  2VSK A;  4XJQ A;  1IVG A;  1W0P A;  3K37 A;  4B7Q A;  4QN3 A;  4MWW A;  1F8B A;  3D11 A;  4MWX A;  1DIL A;  3W09 A;  4YZ2 A;  2AEP A;  2AGS A;  2QWG A;  1NCD N;  4MWQ A;  3TIB A;  3INB A;  2VK6 A;  4H52 A;  4KS3 A;  2XZJ A;  4CPZ A;  4MWY A;  3TIA A;  2BER A;  4GZX A;  4QN5 A;  2YA6 A;  4XJU A;  3SIL A;  2F26 A;  2YA4 A;  2BF6 A;  5M1Z A;  1MS9 A;  4B7M A;  3SAL A;  4K1I A;  2YDP A;  1NMA N;  2QWH A;  4BBW A;  1MS1 A;  2RKC A;  1NN2 A;  1V0F A;  4XYX A;  1INX A;  2HTV A;  2SIM A;  4FPH A;  2AH2 A;  1L7H A;  4GDJ A;  4FP3 A;  1NNC A;  1Z4Y A;  2F29 A;  4MZA A;  4QN4 A;  3A72 A;  4KS4 A;  4GZQ A;  4B7R A;  3TI3 A;  4FJ6 A;  4GZW A;  4XJ8 A;  4MWL A;  2YA5 A;  4CPO A;  4B7N A;  4GJT A;  4FVK A;  1MS0 A;  1V3B A;  2HT8 A;  1IVF A;  2VW1 A;  1L7F A;  2W20 A;  2ZB5 A;  1EUT A;  2VK7 A;  1NCB N;  1N1T A;  2QWK A;  4YW4 A;  4XHX A;  1N1V A;  2QWB A;  1EUS A;  1W21 A;  1Z4Z A;  4FQ4 A;  4XHB A;  4X49 A;  1KIT A;  3K3A A;  1INY A;  5B2D A;  4FPK A;  1W0O A;  2BAT A;  1VCJ A;  2QWA A;  3GVL A;  2QWF A;  2VW2 A;  4MC7 A;  3TI4 A;  4HIZ A;  4MX0 A;  1S0I A;  2F25 A;  4B7J A;  1NCC N;  3CKZ A;  4MWU A;  4XJR A;  1V3D A;  4FOW A;  4WEF A;  3K36 A;  1SO7 A;  2QWC A;  5HUN A;  2HTW A;  1N1Y A;  5B2C A;  2C4L A;  4FOV A;  3D12 A;  1EUR A;  1WCQ A;  2CML A;  4K3Y A;  1SLI A;  2YA8 A;  4YZ1 A;  1VCU A;  2AEQ A;  4M4N A;  2XZI A;  4SLI A;  4MJU A;  2VK5 A;  4XIK A;  1F8D A;  4MWJ A;  2F27 A;  1V0Z A;  1E8U A;  3H73 A;  1NSD A;  4J9T A;  1IVC A;  1ING A;  1MS5 A;  4FZH A;  7NN9 A;  3ALX A;  1INH A;  1W8O A;  4FOY A;  2W5N A;  1A4G A;  1V2I A;  1MR5 A;  2HU4 A;  1MS4 A;  4WA3 A;  1IVB A;  4XJW A;  4XMA A;  3H6J A;  1E8V A;  1MS3 A;  4WA4 A;  2XCY A;  3NSS A;  1SLL A;  4M3M A;  4FOQ A;  4HZX A;  3H71 A;  4K1K A;  3B7E A;  4XIO A;  4MWR A;  1NMB N;  2SLI A;  1INW A;  4NC5 A;  4QN7 A;  4YZ5 A;  4FPJ A;  1MZ5 A;  1N1S A;  5F9T A;  3T1E A;  4DGR A;  4X4A A;  2VSM A;  5HX0 A;  4YW2 A;  1B9T A;  2QWD A;  4Q6K A;  3TIC A;  1S0J A;  5JYY A;  4H53 A;  3JU4 A;  3K38 A;  4M4U A;  4NCS A;  2BZD A;  4WEG A;  4FPY A;  1A4Q A;  2QWE A;  3CL2 A;  2YA7 A;  3H72 A;  4FP2 A;  4KS2 A;  1NNA A;  4K1H A;  1INF A;  1L7G A;  3K39 A;  2W5O A;  1XOE A;  4YW5 A;  4HZZ A;  1USR A;  1DIM A;  2F13 A;  4XMI A;  3O9J A;  1E8T A;  2FHR A;  1MWE A; 
#chains in the Genus database with same CATH topology
 4WA5 A;  5FZN A;  4GZP A;  4IFJ A;  4O5T A;  3P5B L;  4GZO A;  1NCA N;  2FPB A;  1USX A;  3VNH A;  4I00 A;  2Z32 A;  1S1D A;  1IVE A;  2YDT A;  4K1J A;  4ASC A;  2HTQ A;  3OPZ A;  2ZZK A;  1XOG A;  2SIL A;  4JF7 A;  1F8C A;  1NPE A;  1NSB A;  2ISM A;  3SLI A;  1POO A;  3G4E A;  1PJX A;  2IAV A;  4GZT A;  3ALW A;  4L7B A;  4YW1 A;  4N1B A;  4MZE A;  4D8S A;  2HT7 A;  1INV A;  1Z50 A;  4HZY A;  1N6E A;  1E1A A;  2F10 A;  1WP5 A;  1Z4W A;  4CH9 A;  1N6F A;  1ZI0 A;  4G3N A;  1WCS A;  1QBI A;  4XJ9 A;  2VAQ A;  4MJV A;  4XJA A;  4FPF A;  3TC9 A;  4GEZ A;  3TI8 A;  5HUK A;  2F0Z A;  2XZK A;  4GB1 A;  1Z4V A;  2B8H A;  3A9H A;  3B69 A;  4KS5 A;  4CPN A;  2HU0 A;  3O9K A;  5HUM A;  1W1X A;  2OJH A;  4YZ3 A;  2DG0 A;  3A71 A;  2IAU A;  3Q6K A;  4QNP A;  4D4U A;  2WOZ A;  3BEQ A;  4CPL A;  1NSC A;  3AMR A;  1V3E A;  4XIL A;  1IVD A;  4A0P A;  2DG1 A;  2A75 A;  2GVW A;  1V0E A;  4HZW A;  2HTY A;  5F72 C;  1QLG A;  2VW0 A;  3NO0 A;  4MWV A;  4IN4 A;  4AHA A;  1B9S A;  1W8N A;  2QWI A;  4FPC A;  4X47 A;  4AH4 A;  4CPY A;  3ZGD A;  1NMC A;  1CRZ A;  3LI5 A;  1IUC A;  3TI6 A;  3U0S A;  1W20 A;  2F12 A;  2F11 A;  4C1Y A;  1MZ6 A;  1NNB A;  4GDI A;  4KS1 A;  2VVZ A;  3KYA A;  3GVK A;  4YZ4 A;  3V65 B;  4UF7 A;  3GVJ A;  4NN9 A;  2ZB6 A;  2C4A A;  1F8E A;  4FPL A;  6NN9 A;  2VWD A;  4GNB A;  4GN9 A;  1SNT A;  4X6K A;  4CPM A;  2QE8 A;  1Z4X A;  3SOV A;  2FPC A;  4ZGC A;  4M4V A;  2HQS A;  2HT5 A;  2HTU A;  2IAT A;  4AGI A;  3PJQ A;  4GZS A;  2JKB A;  3CYE A;  2GVX A;  4HZV A;  3O4P A;  2QWJ A;  4QN6 A;  1MS8 A;  3A9G A;  3SAN A;  3CL0 A;  4XOG A;  4FPO B;  4L7D A;  2GHS A;  4FPE A;  4FPG A;  4Q1U A;  2W38 A;  3NN9 A;  1H6L A;  4YW3 A;  3S94 A;  2F24 A;  1B9V A;  4IFL X;  2X9M A;  2HTR A;  4XJZ A;  5HUG A;  4XE9 A;  1BJI A;  2F28 A;  4C1Y B;  1A14 N;  5D9D A;  4O5S A;  1EUU A;  1V3C A;  5GX1 A;  5NN9 A;  3TI5 A;  2VSK A;  4XJQ A;  1IVG A;  1W0P A;  3K37 A;  4B7Q A;  4CHB A;  3SOQ A;  4QN3 A;  4MWW A;  1F8B A;  3D11 A;  4MWX A;  1DIL A;  3S2K A;  3W09 A;  1OFZ A;  4YZ2 A;  2AEP A;  2AGS A;  3HRP A;  2QWG A;  3KGG A;  1NCD N;  4AGT A;  4MWQ A;  3TIB A;  1ZGK A;  3INB A;  2VK6 A;  1C5K A;  4H52 A;  3WW9 A;  4KS3 A;  5FZJ A;  2H2U A;  2FLU X;  2XZJ A;  4CPZ A;  4MWY A;  3TIA A;  2W8B A;  2FP8 A;  2BER A;  2IAX A;  4GZX A;  4QN5 A;  5GX4 A;  2YA6 A;  4XJU A;  2GVU A;  1S18 A;  5GTQ A;  3SIL A;  2F26 A;  2YA4 A;  2BF6 A;  5M1Z A;  1MS9 A;  4B7M A;  3SAL A;  4K1I A;  1K32 A;  2YDP A;  1NMA N;  2QWH A;  4IQK A;  3HLH A;  4UOU A;  4BBW A;  3V1S A;  1MS1 A;  2RKC A;  4GNA A;  4GNC A;  1NN2 A;  1V0F A;  3ZGC A;  4XYX A;  1INX A;  2HTV A;  2SIM A;  4FPH A;  2AH2 A;  1L7H A;  2G8S A;  2IAQ A;  4GDJ A;  4FP3 A;  2IAO A;  1NNC A;  1X2R A;  2ZW9 A;  4YY8 A;  1Z4Y A;  4ZY3 A;  2F29 A;  3DAS A;  3LI4 A;  3WDZ A;  4D52 A;  3G4H A;  5GX2 A;  4MZA A;  4QN4 A;  5GX5 A;  3A72 A;  4KS4 A;  4GZQ A;  4B7R A;  4JML A;  3TI3 A;  4FJ6 A;  4GZW A;  4XJ8 A;  4MWL A;  2YA5 A;  4CPO A;  4B7N A;  3VNG A;  4GJT A;  4FVK A;  2W8B B;  4HHO A;  1MS0 A;  1V3B A;  2HT8 A;  1IVF A;  2VW1 A;  1L7F A;  2W20 A;  5EX7 A;  2ZB5 A;  3S8V A;  1IUB A;  1EUT A;  1N6D A;  2VK7 A;  2FP9 A;  1NCB N;  1N1T A;  2QWK A;  4XMB A;  4YW4 A;  2ZWA A;  4XHX A;  1N1V A;  3II7 A;  2IAS A;  3SOB B;  2QWB A;  5EO7 A;  4CSD A;  1C9U A;  1EUS A;  1W21 A;  1Z4Z A;  4FQ4 A;  4XHB A;  4X49 A;  1KIT A;  3SRG A;  3K3A A;  1INY A;  4D52 B;  5B2D A;  4FPK A;  1W0O A;  2BAT A;  1VCJ A;  2QWA A;  2IAP A;  4R40 A;  3GVL A;  4IYG A;  4HW6 A;  2QWF A;  1CRU A;  2VW2 A;  5H47 A;  4MC7 A;  3TI4 A;  4HIZ A;  4MX0 A;  2DSO A;  1S0I A;  2F25 A;  4B7J A;  1NCC N;  3CKZ A;  4MWU A;  4XJR A;  1V3D A;  4FOW A;  5FNU A;  5GX3 A;  4WEF A;  1IJQ A;  1Q7F A;  3K36 A;  4PWZ A;  1SO7 A;  2QWC A;  5HUN A;  2HTW A;  1N1Y A;  5B2C A;  2IAW A;  2C4L A;  4FOV A;  3E5Z A;  3D12 A;  1EUR A;  1WCQ A;  2CML A;  4K3Y A;  4DG6 A;  1SLI A;  2YA8 A;  4YZ1 A;  3Q6P A;  1VCU A;  2AEQ A;  4M4N A;  3UC1 A;  2XZI A;  2V91 A;  4SLI A;  2GVV A;  1RWI A;  1V04 A;  4MJU A;  1U6D X;  2IAR A;  2VK5 A;  3LI3 A;  4XIK A;  1F8D A;  5FNS A;  4MWJ A;  2F27 A;  1V0Z A;  1E8U A;  3H73 A;  1NSD A;  2P4O A;  1IVC A;  4J9T A;  4L7C A;  3WWA A;  1ING A;  5EO8 A;  1MS5 A;  4FZH A;  7NN9 A;  3ALX A;  1INH A;  5FWW A;  1W8O A;  4FOY A;  3AMS A;  2W5N A;  3SRE A;  1A4G A;  4IMB A;  1V2I A;  1MR5 A;  1X2J A;  2HU4 A;  1MS4 A;  3L6V A;  3HLI A;  4WA3 A;  1IVB A;  4XJW A;  4XMA A;  3H6J A;  3I1C A;  1E8V A;  1MS3 A;  3WN7 A;  4WA4 A;  2XCY A;  2XN4 A;  3NSS A;  1SLL A;  1N7D A;  2H2N A;  4M3M A;  4FOQ A;  4HZX A;  3IAX A;  3H71 A;  3V64 C;  4K1K A;  3B7E A;  5FNT A;  5D9C A;  4XIO A;  4MWR A;  1NMB N;  2SLI A;  1INW A;  4NC5 A;  1RWL A;  4QN7 A;  4YZ5 A;  5FNR A;  4FPJ A;  1MZ5 A;  1CQ1 A;  1N1S A;  5F9T A;  3T1E A;  4DGR A;  4X4A A;  4ZLR A;  2VSM A;  5HX0 A;  4YW2 A;  1B9T A;  2QWD A;  4Q6K A;  3FVZ A;  3TIC A;  1S0J A;  5JYY A;  4H53 A;  3JU4 A;  3K38 A;  3Q6T A;  4M4U A;  2BZD A;  4NCS A;  4WEG A;  5D9B A;  2VPJ A;  4FPY A;  4GN7 A;  4IFN X;  3BYC A;  1A4Q A;  2QWE A;  3CL2 A;  2YA7 A;  3S8Z A;  2POO A;  3H72 A;  4FP2 A;  1SUU A;  4KS2 A;  4HHQ A;  1NNA A;  5CGJ A;  4K1H A;  1INF A;  5FNQ A;  1L7G A;  3K39 A;  2W5O A;  1XOE A;  4YW5 A;  4HZZ A;  4GN8 A;  1USR A;  2DYH A;  4D52 C;  3DR2 A;  1DIM A;  1CVM A;  2F13 A;  3FW0 A;  2IVZ A;  3ADE A;  4XMI A;  3O9J A;  1E8T A;  2FHR A;  1MWE A; 
#chains in the Genus database with same CATH homology
 4WA5 A;  4GZP A;  4GZO A;  1NCA N;  1USX A;  4I00 A;  1S1D A;  1IVE A;  2YDT A;  4K1J A;  2HTQ A;  3OPZ A;  1XOG A;  2SIL A;  4JF7 A;  1F8C A;  1NSB A;  3SLI A;  4GZT A;  3ALW A;  4YW1 A;  4MZE A;  4D8S A;  2HT7 A;  1INV A;  1Z50 A;  4HZY A;  2F10 A;  1Z4W A;  1WCS A;  4XJ9 A;  4MJV A;  4XJA A;  4FPF A;  4GEZ A;  3TI8 A;  5HUK A;  2F0Z A;  2XZK A;  4GB1 A;  1Z4V A;  2B8H A;  3B69 A;  4KS5 A;  4CPN A;  2HU0 A;  3O9K A;  5HUM A;  1W1X A;  4YZ3 A;  3A71 A;  4QNP A;  3BEQ A;  4CPL A;  1NSC A;  1V3E A;  4XIL A;  1IVD A;  2A75 A;  1V0E A;  4HZW A;  2HTY A;  2VW0 A;  4MWV A;  1B9S A;  1W8N A;  2QWI A;  4FPC A;  4X47 A;  4CPY A;  1NMC A;  3TI6 A;  1W20 A;  2F12 A;  2F11 A;  1MZ6 A;  1NNB A;  4GDI A;  4KS1 A;  2VVZ A;  3GVK A;  4YZ4 A;  4UF7 A;  3GVJ A;  4NN9 A;  2ZB6 A;  2C4A A;  1F8E A;  4FPL A;  6NN9 A;  2VWD A;  1SNT A;  4X6K A;  4CPM A;  1Z4X A;  4M4V A;  2HT5 A;  2HTU A;  3PJQ A;  4GZS A;  2JKB A;  3CYE A;  4HZV A;  2QWJ A;  4QN6 A;  1MS8 A;  3SAN A;  3CL0 A;  4XOG A;  4FPO B;  4FPE A;  4FPG A;  2W38 A;  3NN9 A;  4YW3 A;  2F24 A;  1B9V A;  2X9M A;  2HTR A;  4XJZ A;  5HUG A;  4XE9 A;  1BJI A;  2F28 A;  1A14 N;  1EUU A;  1V3C A;  5NN9 A;  3TI5 A;  2VSK A;  4XJQ A;  1IVG A;  1W0P A;  3K37 A;  4B7Q A;  4QN3 A;  4MWW A;  1F8B A;  3D11 A;  4MWX A;  1DIL A;  3W09 A;  4YZ2 A;  2AEP A;  2AGS A;  2QWG A;  1NCD N;  4MWQ A;  3TIB A;  3INB A;  2VK6 A;  4H52 A;  4KS3 A;  2H2U A;  2XZJ A;  4CPZ A;  4MWY A;  3TIA A;  2BER A;  4GZX A;  4QN5 A;  2YA6 A;  4XJU A;  1S18 A;  3SIL A;  2F26 A;  2YA4 A;  2BF6 A;  5M1Z A;  1MS9 A;  4B7M A;  3SAL A;  4K1I A;  2YDP A;  1NMA N;  2QWH A;  4BBW A;  1MS1 A;  2RKC A;  1NN2 A;  1V0F A;  4XYX A;  1INX A;  2HTV A;  2SIM A;  4FPH A;  2AH2 A;  1L7H A;  4GDJ A;  4FP3 A;  1NNC A;  1Z4Y A;  2F29 A;  4MZA A;  4QN4 A;  3A72 A;  4KS4 A;  4GZQ A;  4B7R A;  3TI3 A;  4FJ6 A;  4GZW A;  4XJ8 A;  4MWL A;  2YA5 A;  4CPO A;  4B7N A;  4GJT A;  4FVK A;  1MS0 A;  1V3B A;  2HT8 A;  1IVF A;  2VW1 A;  1L7F A;  2W20 A;  2ZB5 A;  1EUT A;  2VK7 A;  1NCB N;  1N1T A;  2QWK A;  4YW4 A;  4XHX A;  1N1V A;  2QWB A;  1EUS A;  1W21 A;  1Z4Z A;  4FQ4 A;  4XHB A;  4X49 A;  1KIT A;  3K3A A;  1INY A;  5B2D A;  4FPK A;  1W0O A;  2BAT A;  1VCJ A;  2QWA A;  3GVL A;  2QWF A;  2VW2 A;  4MC7 A;  3TI4 A;  4HIZ A;  4MX0 A;  1S0I A;  2F25 A;  4B7J A;  1NCC N;  3CKZ A;  4MWU A;  4XJR A;  1V3D A;  4FOW A;  4WEF A;  3K36 A;  1SO7 A;  2QWC A;  5HUN A;  2HTW A;  1N1Y A;  5B2C A;  2C4L A;  4FOV A;  3D12 A;  1EUR A;  1WCQ A;  2CML A;  4K3Y A;  1SLI A;  2YA8 A;  4YZ1 A;  1VCU A;  2AEQ A;  4M4N A;  2XZI A;  4SLI A;  4MJU A;  2VK5 A;  4XIK A;  1F8D A;  4MWJ A;  2F27 A;  1V0Z A;  1E8U A;  3H73 A;  1NSD A;  4J9T A;  1IVC A;  1ING A;  1MS5 A;  4FZH A;  7NN9 A;  3ALX A;  1INH A;  1W8O A;  4FOY A;  2W5N A;  1A4G A;  1V2I A;  1MR5 A;  2HU4 A;  1MS4 A;  4WA3 A;  1IVB A;  4XJW A;  4XMA A;  3H6J A;  1E8V A;  1MS3 A;  4WA4 A;  2XCY A;  3NSS A;  1SLL A;  2H2N A;  4M3M A;  4FOQ A;  4HZX A;  3H71 A;  4K1K A;  3B7E A;  4XIO A;  4MWR A;  1NMB N;  2SLI A;  1INW A;  4NC5 A;  4QN7 A;  4YZ5 A;  4FPJ A;  1MZ5 A;  1N1S A;  5F9T A;  3T1E A;  4DGR A;  4X4A A;  2VSM A;  5HX0 A;  4YW2 A;  1B9T A;  2QWD A;  4Q6K A;  3TIC A;  1S0J A;  5JYY A;  4H53 A;  3JU4 A;  3K38 A;  4M4U A;  4NCS A;  2BZD A;  4WEG A;  4FPY A;  1A4Q A;  2QWE A;  3CL2 A;  2YA7 A;  3H72 A;  4FP2 A;  4KS2 A;  1NNA A;  4K1H A;  1INF A;  1L7G A;  3K39 A;  2W5O A;  1XOE A;  4YW5 A;  4HZZ A;  1USR A;  1DIM A;  2F13 A;  4XMI A;  3O9J A;  1E8T A;  2FHR A;  1MWE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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