2F27A

Crystal structure of the human sialidase neu2 e111q-q112e double mutant in complex with dana inhibitor
Total Genus 110
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
110
sequence length
377
structure length
370
Chain Sequence
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTQEQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLNDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Human Sialidase Neu2 E111Q-Q112E Double Mutant in Complex with DANA Inhibitor
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Sialidase 2
total genus 110
structure length 370
sequence length 377
chains with identical sequence B
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2005-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13088 BNR_2 BNR repeat-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 2f27A00
3SLIA 4XJ9A 2F0ZA 3K37A 3H72A 1SLIA 4QNPA 2BERA 4QN7A 1IVGA 2F28A 2YA4A 1V0EA 4FPOB 2AGSA 2F13A 1SNTA 1INGA 2W5NA 1NCAN 3H71A 1MS5A 4MC7A 3TI6A 1NN2A 5B2CA 1A4GA 1NMCA 2B8HA 4XIKA 1W21A 2QWAA 1F8DA 2BATA 1VCUA 1XOEA 3INBA 4CPYA 1Z4WA 3D11A 4FPFA 2F29A 4K1HA 1KITA 4QN4A 1V3DA 1IVEA 1V3EA 4FP3A 4FPKA 1XOGA 1N1SA 2F12A 4YZ2A 4XIOA 3CL2A 4CPNA 2QWHA 2VK7A 4FP2A 1USRA 4FOYA 4GZTA 4YZ3A 4YW2A 3K36A 1N1YA 5F9TA 4HZYA 4XHBA 4MWXA 1WCQA 2YDPA 4XYXA 3TI3A 3SANA 3JU4A 4YZ5A 2BZDA 3PJQA 4HZXA 4MWJA 4FJ6A 4NN9A 3GVKA 1W8OA 5NN9A 3TI8A 4XJRA 4M4VA 2HTYA 4XILA 4GDJA 4XJAA 2VSKA 1NSBA 4M4NA 3A72A 4Q6KA 4YW3A 2VW2A 4GEZA 4YZ1A 3NSSA 1MR5A 1NMAN 4CPZA 2QWDA 2CMLA 2XCYA 1INHA 2YA5A 3ALXA 2YA7A 1F8CA 1A14N 2F10A 4KS4A 1B9SA 2QWFA 4MWRA 3H6JA 4WA4A 1INXA 1EURA 1B9TA 1S0IA 2HU4A 4QN6A 3TIAA 1L7FA 1Z4VA 2HT5A 4XE9A 4BBWA 5HX0A 1NSCA 1INWA 1DIMA 3TI5A 1NCBN 1W0PA 4GZSA 4X4AA 4MWVA 2HTUA 1INVA 4FPGA 1F8EA 3D12A 4FPYA 1MS9A 5HUNA 3SILA 7NN9A 3CL0A 3O9KA 4QN3A 2QWGA 2QWIA 1EUUA 4GZPA 1NCDN 4B7MA 4K1JA 4QN5A 3GVJA 3A71A 4B7JA 4MX0A 3GVLA 2HTRA 4FOVA 2HT7A 1SLLA 1DILA 3CYEA 4YW1A 1Z50A 4HZVA 2W5OA 4MZEA 4GDIA 4SLIA 2VK5A 2QWEA 4MWUA 4MJUA 4YW4A 1MZ5A 1IVCA 4X49A 2XZJA 3ALWA 4GZXA 1INYA 1SO7A 1V3BA 2HU0A 4FVKA 3K39A 1V3CA 3O9JA 4D8SA 4XJQA 4YZ4A 3H73A 4B7RA 1F8BA 1W0OA 2VK6A 2F26A 1V2IA 2VW1A 2HTQA 1MWEA 2VW0A 4X6KA 4CPOA 2W20A 1N1TA 2JKBA 4H53A 3SALA 2F27A 3W09A 4FPEA 2X9MA 4WEFA 4FOWA 1NCCN 4M4UA 1NMBN 1W20A 1S0JA 2SILA 2QWKA 4XHXA 3TI4A 1Z4XA 1USXA 2BF6A 2QWBA 1BJIA 1MS3A 4FPCA 4GB1A 1E8VA 2AEPA 1MS4A 2ZB6A 4MWYA 5JYYA 1IVDA 4CPMA 2C4LA 1EUSA 2SIMA 4MZAA 2HT8A 2QWCA 2XZIA 3TIBA 4FPLA 4HZWA 4KS1A 4FOQA 1NNCA 1MS1A 1NNAA 4GJTA 4XJZA 4MWQA 6NN9A 2RKCA 1E8UA 2C4AA 1W1XA 2ZB5A 4KS5A 2VSMA 5M1ZA 2W38A 1E8TA 2F24A 4YW5A 4KS3A 3B69A 4XMIA 3TICA 2VVZA 4XJWA 1N1VA 2YA8A 5HUMA 4K3YA 1Z4ZA 1L7GA 4UF7A 2HTVA 4K1KA 2F11A 4FQ4A 4MWWA 2YA6A 4HZZA 4WA5A 4JF7A 2SLIA 4XMAA 4FZHA 2QWJA 1V0FA 1MS8A 4DGRA 1NSDA 5B2DA 4WEGA 4B7QA 4GZWA 4GZQA 4K1IA 2XZKA 4I00A 4XOGA 2F25A 1A4QA 1IVFA 4B7NA 2YDTA 4XJUA 4XJ8A 3B7EA 3K38A 4MWLA 3BEQA 2AH2A 1L7HA 4MJVA 4FPHA 2AEQA 4CPLA 1V0ZA 4NC5A 3CKZA 3K3AA 1Z4YA 3NN9A 1NNBA 4H52A 4FPJA 4NCSA 4HIZA 4J9TA 4X47A 4KS2A 1WCSA 5HUKA 3T1EA 1EUTA 4WA3A 2FHRA 4M3MA 1IVBA 1B9VA 2HTWA 1MS0A 1VCJA 5HUGA 4GZOA 1MZ6A 2A75A 1W8NA 3OPZA 1INFA 2VWDA
chains in the Genus database with same CATH superfamily
3SLIA 4XJ9A 2F0ZA 3K37A 3H72A 3V64C 1SLIA 4QNPA 2BERA 4QN7A 1IVGA 2F28A 2YA4A 1V0EA 4L7BA 4FPOB 4L7DA 2AGSA 2F13A 1SNTA 1INGA 2W5NA 1NCAN 3H71A 2GVXA 3P5BL 1MS5A 3Q6TA 4IQKA 1IUCA 4MC7A 3TI6A 1NN2A 2ZW9A 4AGIA 5B2CA 1A4GA 1NMCA 4L7CA 2B8HA 4Q1UA 4XIKA 1W21A 2QWAA 1RWIA 1F8DA 2BATA 3G4EA 1VCUA 1XOEA 3INBA 4CPYA 3V65B 1Z4WA 3D11A 4FPFA 2F29A 1ZI0A 1QBIA 4K1HA 4AGTA 1X2RA 1KITA 4QN4A 4O5TA 1V3DA 1IVEA 1V3EA 4FP3A 2VPJA 4FPKA 3HLIA 1XOGA 3O4PA 5CGJA 1N1SA 2F12A 3A9GA 4YZ2A 2IAXA 4XIOA 3CL2A 4CPNA 2QWHA 2VK7A 1RWLA 4O5SA 4FP2A 1USRA 4FOYA 4GZTA 4YZ3A 1C9UA 4YW2A 3K36A 1N1YA 3FW0A 5F9TA 1S1DA 4HZYA 4XHBA 4MWXA 3S8VA 1WCQA 2YDPA 5GX1A 1E1AA 4XYXA 3TI3A 3SANA 3JU4A 3KYAA 2VAQA 4YZ5A 2DG0A 2BZDA 2WOZA 3PJQA 4HZXA 4MWJA 4FJ6A 4NN9A 3GVKA 1S18A 1W8OA 5NN9A 3TI8A 4XJRA 4M4VA 2HTYA 4XILA 4GDJA 4XJAA 2VSKA 1NSBA 4M4NA 3A72A 4HHQA 4Q6KA 2HQSA 4YW3A 3LI5A 2IVZA 2VW2A 4GEZA 5EO7A 4YZ1A 3NSSA 1MR5A 1NMAN 4CPZA 2QWDA 4GN8A 4A0PA 5D9DA 2CMLA 2XCYA 4D4UA 1INHA 2YA5A 3ALXA 2YA7A 1F8CA 1A14N 2F10A 2G8SA 4IFNX 3UC1A 4KS4A 1B9SA 2QWFA 4MWRA 4CH9A 3H6JA 4WA4A 3U0SA 1INXA 1EURA 1B9TA 4GN7A 1S0IA 2HU4A 4QN6A 3TIAA 1L7FA 1Z4VA 2HT5A 4XE9A 3S8ZA 1N6DA 4BBWA 4HW6A 5HX0A 1NSCA 1INWA 4XMBA 1DIMA 3TI5A 1NCBN 3ZGCA 1W0PA 4GZSA 4X4AA 4MWVA 2GVVA 2HTUA 1INVA 4GNCA 2Z32A 4FPGA 1F8EA 3D12A 4FPYA 1ZGKA 1MS9A 5HUNA 4IN4A 3SILA 7NN9A 3CL0A 3O9KA 3E5ZA 3S94A 5GTQA 2IAQA 4QN3A 2FLUX 2QWGA 1IUBA 3II7A 5D9BA 4N1BA 2QWIA 1CQ1A 1EUUA 2FPBA 4GZPA 1NCDN 1OFZA 4B7MA 5FNSA 4K1JA 4GNAA 4QN5A 3GVJA 3A71A 4B7JA 5EO8A 4MX0A 3GVLA 3KGGA 3SOBB 5FNQA 2HTRA 4FOVA 2HT7A 4G3NA 1SLLA 3SRGA 2FP9A 1DILA 3CYEA 4YW1A 1Z50A 4HZVA 4UOUA 4IMBA 5FNRA 2W5OA 4MZEA 5F72C 3VNGA 1C5KA 1CVMA 2XN4A 4GDIA 4SLIA 2VK5A 2H2UA 2QWEA 3SOQA 4MWUA 4MJUA 3S2KA 4YW4A 1MZ5A 1IVCA 4X49A 2ISMA 3WW9A 3SOVA 2XZJA 3ALWA 1K32A 4R40A 4GZXA 1INYA 1SO7A 5FZNA 1V3BA 1U6DX 4GNBA 2ZZKA 2IATA 2HU0A 4FVKA 2W8BB 2H2NA 5H47A 3K39A 1QLGA 1V3CA 3O9JA 4D8SA 4XJQA 4YZ4A 3H73A 4B7RA 1F8BA 1W0OA 2VK6A 1V04A 2F26A 1V2IA 2VW1A 1CRZA 2HTQA 1MWEA 2P4OA 2VW0A 4X6KA 1H6LA 5GX4A 2IASA 2DG1A 3DR2A 4CPOA 2W20A 1N1TA 4GN9A 2JKBA 5EX7A 3V1SA 4H53A 5FNUA 3SALA 2F27A 3A9HA 3W09A 4FPEA 5D9CA 3HLHA 2X9MA 3LI3A 4FOWA 4WEFA 1NCCN 1N6EA 4M4UA 1NMBN 1W20A 1S0JA 2SILA 4C1YA 2QWKA 4XHXA 3TI4A 1Z4XA 1USXA 2BF6A 3FVZA 2QWBA 1BJIA 1MS3A 4IFLX 4FPCA 4GB1A 2IAOA 1E8VA 2AEPA 1MS4A 2ZB6A 3SREA 4MWYA 2POOA 5JYYA 3G4HA 3WWAA 1IVDA 4CPMA 4AH4A 4D52B 2C4LA 3I1CA 1EUSA 4ZY3A 4ZLRA 2SIMA 4MZAA 2HT8A 3ADEA 1N6FA 5FZJA 2QWCA 2IAWA 2XZIA 3TIBA 4CHBA 4FPLA 4HZWA 5GX5A 4KS1A 2W8BA 1WP5A 4FOQA 1NNCA 1MS1A 1NNAA 3DASA 3Q6KA 4GJTA 3Q6PA 4XJZA 1CRUA 4MWQA 2IAVA 3L6VA 6NN9A 5FWWA 5GX2A 2RKCA 4C1YB 1E8UA 2C4AA 2DYHA 1W1XA 2ZB5A 4KS5A 4HHOA 2VSMA 5M1ZA 1IJQA 2W38A 1E8TA 1Q7FA 3HRPA 1SUUA 5FNTA 2F24A 4YW5A 4KS3A 3AMSA 4PWZA 3B69A 4XMIA 3TICA 2VVZA 4XJWA 1N1VA 2YA8A 5HUMA 3BYCA 2GVWA 2GHSA 1Z4ZA 1L7GA 4K3YA 3TC9A 4UF7A 2HTVA 4K1KA 2F11A 4FQ4A 4MWWA 2YA6A 4HZZA 4WA5A 4JF7A 3WN7A 2SLIA 2FPCA 3LI4A 4DG6A 4XMAA 4FZHA 2QWJA 1V0FA 1MS8A 4AHAA 2IAPA 4DGRA 1NSDA 5B2DA 4WEGA 4B7QA 1POOA 4GZWA 4GZQA 4K1IA 2XZKA 3NO0A 4I00A 4D52A 4D52C 4XOGA 4ASCA 2F25A 2ZWAA 1A4QA 1IVFA 4B7NA 2IAUA 2IARA 4CSDA 2YDTA 4XJUA 3AMRA 4XJ8A 3B7EA 3K38A 4MWLA 3BEQA 2AH2A 1L7HA 4IYGA 4ZGCA 4MJVA 4FPHA 2AEQA 4CPLA 1V0ZA 4NC5A 3CKZA 3K3AA 1N7DA 1Z4YA 4IFJA 3NN9A 1NNBA 4H52A 4FPJA 4HIZA 4NCSA 4J9TA 3ZGDA 4X47A 4KS2A 1WCSA 5GX3A 5HUKA 3T1EA 1EUTA 1PJXA 2GVUA 2V91A 4WA3A 1NPEA 1X2JA 2FHRA 4YY8A 4M3MA 4JMLA 1IVBA 1B9VA 3IAXA 2HTWA 1MS0A 1VCJA 5HUGA 2DSOA 4GZOA 1MZ6A 3WDZA 2A75A 2OJHA 2FP8A 1W8NA 3OPZA 2QE8A 1INFA 2VWDA 3VNHA
chains in the Genus database with same CATH topology
3SLIA 4XJ9A 2F0ZA 3K37A 3H72A 1SLIA 4QNPA 2BERA 4QN7A 1IVGA 2F28A 2YA4A 1V0EA 4FPOB 2AGSA 2F13A 1SNTA 1INGA 2W5NA 1NCAN 3H71A 1MS5A 4MC7A 3TI6A 1NN2A 5B2CA 1A4GA 1NMCA 2B8HA 4XIKA 1W21A 2QWAA 1F8DA 2BATA 1VCUA 1XOEA 3INBA 4CPYA 1Z4WA 3D11A 4FPFA 2F29A 4K1HA 1KITA 4QN4A 1V3DA 1IVEA 1V3EA 4FP3A 4FPKA 1XOGA 1N1SA 2F12A 4YZ2A 4XIOA 3CL2A 4CPNA 2QWHA 2VK7A 4FP2A 1USRA 4FOYA 4GZTA 4YZ3A 4YW2A 3K36A 1N1YA 5F9TA 1S1DA 4HZYA 4XHBA 4MWXA 1WCQA 2YDPA 4XYXA 3TI3A 3SANA 3JU4A 4YZ5A 2BZDA 3PJQA 4HZXA 4MWJA 4FJ6A 4NN9A 3GVKA 1S18A 1W8OA 5NN9A 3TI8A 4XJRA 4M4VA 2HTYA 4XILA 4GDJA 4XJAA 2VSKA 1NSBA 4M4NA 3A72A 4Q6KA 4YW3A 2VW2A 4GEZA 4YZ1A 3NSSA 1MR5A 1NMAN 4CPZA 2QWDA 2CMLA 2XCYA 1INHA 2YA5A 3ALXA 2YA7A 1F8CA 1A14N 2F10A 4KS4A 1B9SA 2QWFA 4MWRA 3H6JA 4WA4A 1INXA 1EURA 1B9TA 1S0IA 2HU4A 4QN6A 3TIAA 1L7FA 1Z4VA 2HT5A 4XE9A 4BBWA 5HX0A 1NSCA 1INWA 1DIMA 3TI5A 1NCBN 1W0PA 4GZSA 4X4AA 4MWVA 2HTUA 1INVA 4FPGA 1F8EA 3D12A 4FPYA 1MS9A 5HUNA 3SILA 7NN9A 3CL0A 3O9KA 4QN3A 2QWGA 2QWIA 1EUUA 4GZPA 1NCDN 4B7MA 4K1JA 4QN5A 3GVJA 3A71A 4B7JA 4MX0A 3GVLA 2HTRA 4FOVA 2HT7A 1SLLA 1DILA 3CYEA 4YW1A 1Z50A 4HZVA 2W5OA 4MZEA 4GDIA 4SLIA 2VK5A 2H2UA 2QWEA 4MWUA 4MJUA 4YW4A 1MZ5A 1IVCA 4X49A 2XZJA 3ALWA 4GZXA 1INYA 1SO7A 1V3BA 2HU0A 4FVKA 2H2NA 3K39A 1V3CA 3O9JA 4D8SA 4XJQA 4YZ4A 3H73A 4B7RA 1F8BA 1W0OA 2VK6A 2F26A 1V2IA 2VW1A 2HTQA 1MWEA 2VW0A 4X6KA 4CPOA 2W20A 1N1TA 2JKBA 4H53A 3SALA 2F27A 3W09A 4FPEA 2X9MA 4WEFA 4FOWA 1NCCN 4M4UA 1NMBN 1W20A 1S0JA 2SILA 2QWKA 4XHXA 3TI4A 1Z4XA 1USXA 2BF6A 2QWBA 1BJIA 1MS3A 4FPCA 4GB1A 1E8VA 2AEPA 1MS4A 2ZB6A 4MWYA 5JYYA 1IVDA 4CPMA 2C4LA 1EUSA 2SIMA 4MZAA 2HT8A 2QWCA 2XZIA 3TIBA 4FPLA 4HZWA 4KS1A 4FOQA 1NNCA 1MS1A 1NNAA 4GJTA 4XJZA 4MWQA 6NN9A 2RKCA 1E8UA 2C4AA 1W1XA 2ZB5A 4KS5A 2VSMA 5M1ZA 2W38A 1E8TA 2F24A 4YW5A 4KS3A 3B69A 4XMIA 3TICA 2VVZA 4XJWA 1N1VA 2YA8A 5HUMA 4K3YA 1Z4ZA 1L7GA 4UF7A 2HTVA 4K1KA 2F11A 4FQ4A 4MWWA 2YA6A 4HZZA 4WA5A 4JF7A 2SLIA 4XMAA 4FZHA 2QWJA 1V0FA 1MS8A 4DGRA 1NSDA 5B2DA 4WEGA 4B7QA 4GZWA 4GZQA 4K1IA 2XZKA 4I00A 4XOGA 2F25A 1A4QA 1IVFA 4B7NA 2YDTA 4XJUA 4XJ8A 3B7EA 3K38A 4MWLA 3BEQA 2AH2A 1L7HA 4MJVA 4FPHA 2AEQA 4CPLA 1V0ZA 4NC5A 3CKZA 3K3AA 1Z4YA 3NN9A 1NNBA 4H52A 4FPJA 4NCSA 4HIZA 4J9TA 4X47A 4KS2A 1WCSA 5HUKA 3T1EA 1EUTA 4WA3A 2FHRA 4M3MA 1IVBA 1B9VA 2HTWA 1MS0A 1VCJA 5HUGA 4GZOA 1MZ6A 2A75A 1W8NA 3OPZA 1INFA 2VWDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3SLI A;  4XJ9 A;  2F0Z A;  3K37 A;  3H72 A;  1SLI A;  4QNP A;  2BER A;  4QN7 A;  1IVG A;  2F28 A;  2YA4 A;  1V0E A;  4FPO B;  2AGS A;  2F13 A;  1SNT A;  1ING A;  2W5N A;  1NCA N;  3H71 A;  1MS5 A;  4MC7 A;  3TI6 A;  1NN2 A;  5B2C A;  1A4G A;  1NMC A;  2B8H A;  4XIK A;  1W21 A;  2QWA A;  1F8D A;  2BAT A;  1VCU A;  1XOE A;  3INB A;  4CPY A;  1Z4W A;  3D11 A;  4FPF A;  2F29 A;  4K1H A;  1KIT A;  4QN4 A;  1V3D A;  1IVE A;  1V3E A;  4FP3 A;  4FPK A;  1XOG A;  1N1S A;  2F12 A;  4YZ2 A;  4XIO A;  3CL2 A;  4CPN A;  2QWH A;  2VK7 A;  4FP2 A;  1USR A;  4FOY A;  4GZT A;  4YZ3 A;  4YW2 A;  3K36 A;  1N1Y A;  5F9T A;  4HZY A;  4XHB A;  4MWX A;  1WCQ A;  2YDP A;  4XYX A;  3TI3 A;  3SAN A;  3JU4 A;  4YZ5 A;  2BZD A;  3PJQ A;  4HZX A;  4MWJ A;  4FJ6 A;  4NN9 A;  3GVK A;  1W8O A;  5NN9 A;  3TI8 A;  4XJR A;  4M4V A;  2HTY A;  4XIL A;  4GDJ A;  4XJA A;  2VSK A;  1NSB A;  4M4N A;  3A72 A;  4Q6K A;  4YW3 A;  2VW2 A;  4GEZ A;  4YZ1 A;  3NSS A;  1MR5 A;  1NMA N;  4CPZ A;  2QWD A;  2CML A;  2XCY A;  1INH A;  2YA5 A;  3ALX A;  2YA7 A;  1F8C A;  1A14 N;  2F10 A;  4KS4 A;  1B9S A;  2QWF A;  4MWR A;  3H6J A;  4WA4 A;  1INX A;  1EUR A;  1B9T A;  1S0I A;  2HU4 A;  4QN6 A;  3TIA A;  1L7F A;  1Z4V A;  2HT5 A;  4XE9 A;  4BBW A;  5HX0 A;  1NSC A;  1INW A;  1DIM A;  3TI5 A;  1NCB N;  1W0P A;  4GZS A;  4X4A A;  4MWV A;  2HTU A;  1INV A;  4FPG A;  1F8E A;  3D12 A;  4FPY A;  1MS9 A;  5HUN A;  3SIL A;  7NN9 A;  3CL0 A;  3O9K A;  4QN3 A;  2QWG A;  2QWI A;  1EUU A;  4GZP A;  1NCD N;  4B7M A;  4K1J A;  4QN5 A;  3GVJ A;  3A71 A;  4B7J A;  4MX0 A;  3GVL A;  2HTR A;  4FOV A;  2HT7 A;  1SLL A;  1DIL A;  3CYE A;  4YW1 A;  1Z50 A;  4HZV A;  2W5O A;  4MZE A;  4GDI A;  4SLI A;  2VK5 A;  2QWE A;  4MWU A;  4MJU A;  4YW4 A;  1MZ5 A;  1IVC A;  4X49 A;  2XZJ A;  3ALW A;  4GZX A;  1INY A;  1SO7 A;  1V3B A;  2HU0 A;  4FVK A;  3K39 A;  1V3C A;  3O9J A;  4D8S A;  4XJQ A;  4YZ4 A;  3H73 A;  4B7R A;  1F8B A;  1W0O A;  2VK6 A;  2F26 A;  1V2I A;  2VW1 A;  2HTQ A;  1MWE A;  2VW0 A;  4X6K A;  4CPO A;  2W20 A;  1N1T A;  2JKB A;  4H53 A;  3SAL A;  2F27 A;  3W09 A;  4FPE A;  2X9M A;  4WEF A;  4FOW A;  1NCC N;  4M4U A;  1NMB N;  1W20 A;  1S0J A;  2SIL A;  2QWK A;  4XHX A;  3TI4 A;  1Z4X A;  1USX A;  2BF6 A;  2QWB A;  1BJI A;  1MS3 A;  4FPC A;  4GB1 A;  1E8V A;  2AEP A;  1MS4 A;  2ZB6 A;  4MWY A;  5JYY A;  1IVD A;  4CPM A;  2C4L A;  1EUS A;  2SIM A;  4MZA A;  2HT8 A;  2QWC A;  2XZI A;  3TIB A;  4FPL A;  4HZW A;  4KS1 A;  4FOQ A;  1NNC A;  1MS1 A;  1NNA A;  4GJT A;  4XJZ A;  4MWQ A;  6NN9 A;  2RKC A;  1E8U A;  2C4A A;  1W1X A;  2ZB5 A;  4KS5 A;  2VSM A;  5M1Z A;  2W38 A;  1E8T A;  2F24 A;  4YW5 A;  4KS3 A;  3B69 A;  4XMI A;  3TIC A;  2VVZ A;  4XJW A;  1N1V A;  2YA8 A;  5HUM A;  4K3Y A;  1Z4Z A;  1L7G A;  4UF7 A;  2HTV A;  4K1K A;  2F11 A;  4FQ4 A;  4MWW A;  2YA6 A;  4HZZ A;  4WA5 A;  4JF7 A;  2SLI A;  4XMA A;  4FZH A;  2QWJ A;  1V0F A;  1MS8 A;  4DGR A;  1NSD A;  5B2D A;  4WEG A;  4B7Q A;  4GZW A;  4GZQ A;  4K1I A;  2XZK A;  4I00 A;  4XOG A;  2F25 A;  1A4Q A;  1IVF A;  4B7N A;  2YDT A;  4XJU A;  4XJ8 A;  3B7E A;  3K38 A;  4MWL A;  3BEQ A;  2AH2 A;  1L7H A;  4MJV A;  4FPH A;  2AEQ A;  4CPL A;  1V0Z A;  4NC5 A;  3CKZ A;  3K3A A;  1Z4Y A;  3NN9 A;  1NNB A;  4H52 A;  4FPJ A;  4NCS A;  4HIZ A;  4J9T A;  4X47 A;  4KS2 A;  1WCS A;  5HUK A;  3T1E A;  1EUT A;  4WA3 A;  2FHR A;  4M3M A;  1IVB A;  1B9V A;  2HTW A;  1MS0 A;  1VCJ A;  5HUG A;  4GZO A;  1MZ6 A;  2A75 A;  1W8N A;  3OPZ A;  1INF A;  2VWD A; 
#chains in the Genus database with same CATH topology
 3SLI A;  4XJ9 A;  2F0Z A;  3K37 A;  3H72 A;  3V64 C;  1SLI A;  4QNP A;  2BER A;  4QN7 A;  1IVG A;  2F28 A;  2YA4 A;  1V0E A;  4L7B A;  4FPO B;  4L7D A;  2AGS A;  2F13 A;  1SNT A;  1ING A;  2W5N A;  1NCA N;  3H71 A;  2GVX A;  3P5B L;  1MS5 A;  3Q6T A;  4IQK A;  1IUC A;  4MC7 A;  3TI6 A;  1NN2 A;  2ZW9 A;  4AGI A;  5B2C A;  1A4G A;  1NMC A;  4L7C A;  2B8H A;  4Q1U A;  4XIK A;  1W21 A;  2QWA A;  1RWI A;  1F8D A;  2BAT A;  3G4E A;  1VCU A;  1XOE A;  3INB A;  4CPY A;  3V65 B;  1Z4W A;  3D11 A;  4FPF A;  2F29 A;  1ZI0 A;  1QBI A;  4K1H A;  4AGT A;  1X2R A;  1KIT A;  4QN4 A;  4O5T A;  1V3D A;  1IVE A;  1V3E A;  4FP3 A;  2VPJ A;  4FPK A;  3HLI A;  1XOG A;  3O4P A;  5CGJ A;  1N1S A;  2F12 A;  3A9G A;  4YZ2 A;  2IAX A;  4XIO A;  3CL2 A;  4CPN A;  2QWH A;  2VK7 A;  1RWL A;  4O5S A;  4FP2 A;  1USR A;  4FOY A;  4GZT A;  4YZ3 A;  1C9U A;  4YW2 A;  3K36 A;  1N1Y A;  3FW0 A;  5F9T A;  1S1D A;  4HZY A;  4XHB A;  4MWX A;  3S8V A;  1WCQ A;  2YDP A;  5GX1 A;  1E1A A;  4XYX A;  3TI3 A;  3SAN A;  3JU4 A;  3KYA A;  2VAQ A;  4YZ5 A;  2DG0 A;  2BZD A;  2WOZ A;  3PJQ A;  4HZX A;  4MWJ A;  4FJ6 A;  4NN9 A;  3GVK A;  1S18 A;  1W8O A;  5NN9 A;  3TI8 A;  4XJR A;  4M4V A;  2HTY A;  4XIL A;  4GDJ A;  4XJA A;  2VSK A;  1NSB A;  4M4N A;  3A72 A;  4HHQ A;  4Q6K A;  2HQS A;  4YW3 A;  3LI5 A;  2IVZ A;  2VW2 A;  4GEZ A;  5EO7 A;  4YZ1 A;  3NSS A;  1MR5 A;  1NMA N;  4CPZ A;  2QWD A;  4GN8 A;  4A0P A;  5D9D A;  2CML A;  2XCY A;  4D4U A;  1INH A;  2YA5 A;  3ALX A;  2YA7 A;  1F8C A;  1A14 N;  2F10 A;  2G8S A;  4IFN X;  3UC1 A;  4KS4 A;  1B9S A;  2QWF A;  4MWR A;  4CH9 A;  3H6J A;  4WA4 A;  3U0S A;  1INX A;  1EUR A;  1B9T A;  4GN7 A;  1S0I A;  2HU4 A;  4QN6 A;  3TIA A;  1L7F A;  1Z4V A;  2HT5 A;  4XE9 A;  3S8Z A;  1N6D A;  4BBW A;  4HW6 A;  5HX0 A;  1NSC A;  1INW A;  4XMB A;  1DIM A;  3TI5 A;  1NCB N;  3ZGC A;  1W0P A;  4GZS A;  4X4A A;  4MWV A;  2GVV A;  2HTU A;  1INV A;  4GNC A;  2Z32 A;  4FPG A;  1F8E A;  3D12 A;  4FPY A;  1ZGK A;  1MS9 A;  5HUN A;  4IN4 A;  3SIL A;  7NN9 A;  3CL0 A;  3O9K A;  3E5Z A;  3S94 A;  5GTQ A;  2IAQ A;  4QN3 A;  2FLU X;  2QWG A;  1IUB A;  3II7 A;  5D9B A;  4N1B A;  2QWI A;  1CQ1 A;  1EUU A;  2FPB A;  4GZP A;  1NCD N;  1OFZ A;  4B7M A;  5FNS A;  4K1J A;  4GNA A;  4QN5 A;  3GVJ A;  3A71 A;  4B7J A;  5EO8 A;  4MX0 A;  3GVL A;  3KGG A;  3SOB B;  5FNQ A;  2HTR A;  4FOV A;  2HT7 A;  4G3N A;  1SLL A;  3SRG A;  2FP9 A;  1DIL A;  3CYE A;  4YW1 A;  1Z50 A;  4HZV A;  4UOU A;  4IMB A;  5FNR A;  2W5O A;  4MZE A;  5F72 C;  3VNG A;  1C5K A;  1CVM A;  2XN4 A;  4GDI A;  4SLI A;  2VK5 A;  2H2U A;  2QWE A;  3SOQ A;  4MWU A;  4MJU A;  3S2K A;  4YW4 A;  1MZ5 A;  1IVC A;  4X49 A;  2ISM A;  3WW9 A;  3SOV A;  2XZJ A;  3ALW A;  1K32 A;  4R40 A;  4GZX A;  1INY A;  1SO7 A;  5FZN A;  1V3B A;  1U6D X;  4GNB A;  2ZZK A;  2IAT A;  2HU0 A;  4FVK A;  2W8B B;  2H2N A;  5H47 A;  3K39 A;  1QLG A;  1V3C A;  3O9J A;  4D8S A;  4XJQ A;  4YZ4 A;  3H73 A;  4B7R A;  1F8B A;  1W0O A;  2VK6 A;  1V04 A;  2F26 A;  1V2I A;  2VW1 A;  1CRZ A;  2HTQ A;  1MWE A;  2P4O A;  2VW0 A;  4X6K A;  1H6L A;  5GX4 A;  2IAS A;  2DG1 A;  3DR2 A;  4CPO A;  2W20 A;  1N1T A;  4GN9 A;  2JKB A;  5EX7 A;  3V1S A;  4H53 A;  5FNU A;  3SAL A;  2F27 A;  3A9H A;  3W09 A;  4FPE A;  5D9C A;  3HLH A;  2X9M A;  3LI3 A;  4FOW A;  4WEF A;  1NCC N;  1N6E A;  4M4U A;  1NMB N;  1W20 A;  1S0J A;  2SIL A;  4C1Y A;  2QWK A;  4XHX A;  3TI4 A;  1Z4X A;  1USX A;  2BF6 A;  3FVZ A;  2QWB A;  1BJI A;  1MS3 A;  4IFL X;  4FPC A;  4GB1 A;  2IAO A;  1E8V A;  2AEP A;  1MS4 A;  2ZB6 A;  3SRE A;  4MWY A;  2POO A;  5JYY A;  3G4H A;  3WWA A;  1IVD A;  4CPM A;  4AH4 A;  4D52 B;  2C4L A;  3I1C A;  1EUS A;  4ZY3 A;  4ZLR A;  2SIM A;  4MZA A;  2HT8 A;  3ADE A;  1N6F A;  5FZJ A;  2QWC A;  2IAW A;  2XZI A;  3TIB A;  4CHB A;  4FPL A;  4HZW A;  5GX5 A;  4KS1 A;  2W8B A;  1WP5 A;  4FOQ A;  1NNC A;  1MS1 A;  1NNA A;  3DAS A;  3Q6K A;  4GJT A;  3Q6P A;  4XJZ A;  1CRU A;  4MWQ A;  2IAV A;  3L6V A;  6NN9 A;  5FWW A;  5GX2 A;  2RKC A;  4C1Y B;  1E8U A;  2C4A A;  2DYH A;  1W1X A;  2ZB5 A;  4KS5 A;  4HHO A;  2VSM A;  5M1Z A;  1IJQ A;  2W38 A;  1E8T A;  1Q7F A;  3HRP A;  1SUU A;  5FNT A;  2F24 A;  4YW5 A;  4KS3 A;  3AMS A;  4PWZ A;  3B69 A;  4XMI A;  3TIC A;  2VVZ A;  4XJW A;  1N1V A;  2YA8 A;  5HUM A;  3BYC A;  2GVW A;  2GHS A;  1Z4Z A;  1L7G A;  4K3Y A;  3TC9 A;  4UF7 A;  2HTV A;  4K1K A;  2F11 A;  4FQ4 A;  4MWW A;  2YA6 A;  4HZZ A;  4WA5 A;  4JF7 A;  3WN7 A;  2SLI A;  2FPC A;  3LI4 A;  4DG6 A;  4XMA A;  4FZH A;  2QWJ A;  1V0F A;  1MS8 A;  4AHA A;  2IAP A;  4DGR A;  1NSD A;  5B2D A;  4WEG A;  4B7Q A;  1POO A;  4GZW A;  4GZQ A;  4K1I A;  2XZK A;  3NO0 A;  4I00 A;  4D52 A;  4D52 C;  4XOG A;  4ASC A;  2F25 A;  2ZWA A;  1A4Q A;  1IVF A;  4B7N A;  2IAU A;  2IAR A;  4CSD A;  2YDT A;  4XJU A;  3AMR A;  4XJ8 A;  3B7E A;  3K38 A;  4MWL A;  3BEQ A;  2AH2 A;  1L7H A;  4IYG A;  4ZGC A;  4MJV A;  4FPH A;  2AEQ A;  4CPL A;  1V0Z A;  4NC5 A;  3CKZ A;  3K3A A;  1N7D A;  1Z4Y A;  4IFJ A;  3NN9 A;  1NNB A;  4H52 A;  4FPJ A;  4HIZ A;  4NCS A;  4J9T A;  3ZGD A;  4X47 A;  4KS2 A;  1WCS A;  5GX3 A;  5HUK A;  3T1E A;  1EUT A;  1PJX A;  2GVU A;  2V91 A;  4WA3 A;  1NPE A;  1X2J A;  2FHR A;  4YY8 A;  4M3M A;  4JML A;  1IVB A;  1B9V A;  3IAX A;  2HTW A;  1MS0 A;  1VCJ A;  5HUG A;  2DSO A;  4GZO A;  1MZ6 A;  3WDZ A;  2A75 A;  2OJH A;  2FP8 A;  1W8N A;  3OPZ A;  2QE8 A;  1INF A;  2VWD A;  3VNH A; 
#chains in the Genus database with same CATH homology
 3SLI A;  4XJ9 A;  2F0Z A;  3K37 A;  3H72 A;  1SLI A;  4QNP A;  2BER A;  4QN7 A;  1IVG A;  2F28 A;  2YA4 A;  1V0E A;  4FPO B;  2AGS A;  2F13 A;  1SNT A;  1ING A;  2W5N A;  1NCA N;  3H71 A;  1MS5 A;  4MC7 A;  3TI6 A;  1NN2 A;  5B2C A;  1A4G A;  1NMC A;  2B8H A;  4XIK A;  1W21 A;  2QWA A;  1F8D A;  2BAT A;  1VCU A;  1XOE A;  3INB A;  4CPY A;  1Z4W A;  3D11 A;  4FPF A;  2F29 A;  4K1H A;  1KIT A;  4QN4 A;  1V3D A;  1IVE A;  1V3E A;  4FP3 A;  4FPK A;  1XOG A;  1N1S A;  2F12 A;  4YZ2 A;  4XIO A;  3CL2 A;  4CPN A;  2QWH A;  2VK7 A;  4FP2 A;  1USR A;  4FOY A;  4GZT A;  4YZ3 A;  4YW2 A;  3K36 A;  1N1Y A;  5F9T A;  1S1D A;  4HZY A;  4XHB A;  4MWX A;  1WCQ A;  2YDP A;  4XYX A;  3TI3 A;  3SAN A;  3JU4 A;  4YZ5 A;  2BZD A;  3PJQ A;  4HZX A;  4MWJ A;  4FJ6 A;  4NN9 A;  3GVK A;  1S18 A;  1W8O A;  5NN9 A;  3TI8 A;  4XJR A;  4M4V A;  2HTY A;  4XIL A;  4GDJ A;  4XJA A;  2VSK A;  1NSB A;  4M4N A;  3A72 A;  4Q6K A;  4YW3 A;  2VW2 A;  4GEZ A;  4YZ1 A;  3NSS A;  1MR5 A;  1NMA N;  4CPZ A;  2QWD A;  2CML A;  2XCY A;  1INH A;  2YA5 A;  3ALX A;  2YA7 A;  1F8C A;  1A14 N;  2F10 A;  4KS4 A;  1B9S A;  2QWF A;  4MWR A;  3H6J A;  4WA4 A;  1INX A;  1EUR A;  1B9T A;  1S0I A;  2HU4 A;  4QN6 A;  3TIA A;  1L7F A;  1Z4V A;  2HT5 A;  4XE9 A;  4BBW A;  5HX0 A;  1NSC A;  1INW A;  1DIM A;  3TI5 A;  1NCB N;  1W0P A;  4GZS A;  4X4A A;  4MWV A;  2HTU A;  1INV A;  4FPG A;  1F8E A;  3D12 A;  4FPY A;  1MS9 A;  5HUN A;  3SIL A;  7NN9 A;  3CL0 A;  3O9K A;  4QN3 A;  2QWG A;  2QWI A;  1EUU A;  4GZP A;  1NCD N;  4B7M A;  4K1J A;  4QN5 A;  3GVJ A;  3A71 A;  4B7J A;  4MX0 A;  3GVL A;  2HTR A;  4FOV A;  2HT7 A;  1SLL A;  1DIL A;  3CYE A;  4YW1 A;  1Z50 A;  4HZV A;  2W5O A;  4MZE A;  4GDI A;  4SLI A;  2VK5 A;  2H2U A;  2QWE A;  4MWU A;  4MJU A;  4YW4 A;  1MZ5 A;  1IVC A;  4X49 A;  2XZJ A;  3ALW A;  4GZX A;  1INY A;  1SO7 A;  1V3B A;  2HU0 A;  4FVK A;  2H2N A;  3K39 A;  1V3C A;  3O9J A;  4D8S A;  4XJQ A;  4YZ4 A;  3H73 A;  4B7R A;  1F8B A;  1W0O A;  2VK6 A;  2F26 A;  1V2I A;  2VW1 A;  2HTQ A;  1MWE A;  2VW0 A;  4X6K A;  4CPO A;  2W20 A;  1N1T A;  2JKB A;  4H53 A;  3SAL A;  2F27 A;  3W09 A;  4FPE A;  2X9M A;  4WEF A;  4FOW A;  1NCC N;  4M4U A;  1NMB N;  1W20 A;  1S0J A;  2SIL A;  2QWK A;  4XHX A;  3TI4 A;  1Z4X A;  1USX A;  2BF6 A;  2QWB A;  1BJI A;  1MS3 A;  4FPC A;  4GB1 A;  1E8V A;  2AEP A;  1MS4 A;  2ZB6 A;  4MWY A;  5JYY A;  1IVD A;  4CPM A;  2C4L A;  1EUS A;  2SIM A;  4MZA A;  2HT8 A;  2QWC A;  2XZI A;  3TIB A;  4FPL A;  4HZW A;  4KS1 A;  4FOQ A;  1NNC A;  1MS1 A;  1NNA A;  4GJT A;  4XJZ A;  4MWQ A;  6NN9 A;  2RKC A;  1E8U A;  2C4A A;  1W1X A;  2ZB5 A;  4KS5 A;  2VSM A;  5M1Z A;  2W38 A;  1E8T A;  2F24 A;  4YW5 A;  4KS3 A;  3B69 A;  4XMI A;  3TIC A;  2VVZ A;  4XJW A;  1N1V A;  2YA8 A;  5HUM A;  4K3Y A;  1Z4Z A;  1L7G A;  4UF7 A;  2HTV A;  4K1K A;  2F11 A;  4FQ4 A;  4MWW A;  2YA6 A;  4HZZ A;  4WA5 A;  4JF7 A;  2SLI A;  4XMA A;  4FZH A;  2QWJ A;  1V0F A;  1MS8 A;  4DGR A;  1NSD A;  5B2D A;  4WEG A;  4B7Q A;  4GZW A;  4GZQ A;  4K1I A;  2XZK A;  4I00 A;  4XOG A;  2F25 A;  1A4Q A;  1IVF A;  4B7N A;  2YDT A;  4XJU A;  4XJ8 A;  3B7E A;  3K38 A;  4MWL A;  3BEQ A;  2AH2 A;  1L7H A;  4MJV A;  4FPH A;  2AEQ A;  4CPL A;  1V0Z A;  4NC5 A;  3CKZ A;  3K3A A;  1Z4Y A;  3NN9 A;  1NNB A;  4H52 A;  4FPJ A;  4NCS A;  4HIZ A;  4J9T A;  4X47 A;  4KS2 A;  1WCS A;  5HUK A;  3T1E A;  1EUT A;  4WA3 A;  2FHR A;  4M3M A;  1IVB A;  1B9V A;  2HTW A;  1MS0 A;  1VCJ A;  5HUG A;  4GZO A;  1MZ6 A;  2A75 A;  1W8N A;  3OPZ A;  1INF A;  2VWD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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