2F29A

Crystal structure of the human sialidase neu2 q116e mutant in complex with dana inhibitor
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
377
structure length
370
Chain Sequence
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFLFFIAIPGQVTEQQQLETRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLNDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSHDHGRTWARGHFVAQDTLECQVAEVEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSPAQWLLYTHPTHSWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the Human Sialidase Neu2 Q116E Mutant in Complex with DANA Inhibitor
rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Sialidase 2
total genus 90
structure length 370
sequence length 377
chains with identical sequence B
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2005-11-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13088 BNR_2 BNR repeat-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 2f29A00
1EURA 2AEQA 2HU4A 4MWLA 1INFA 4M4UA 1NNCA 1BJIA 3GVJA 1SO7A 2VW1A 1E8TA 4X47A 1IVGA 2FHRA 1INXA 5B2CA 4MX0A 4XJRA 2XZJA 4KS5A 4YZ4A 4HZZA 3ALXA 2XZKA 1EUUA 4FQ4A 2F0ZA 4MWYA 2XCYA 4FPEA 4FOVA 2VW2A 4MWWA 1MWEA 4H53A 1IVFA 2JKBA 4GDJA 4K1IA 3K36A 1L7GA 4WEGA 4NN9A 3JU4A 5F9TA 4CPOA 4FP3A 4M4VA 4QN5A 2VK5A 4YW5A 1W0OA 3H6JA 4D8SA 1W0PA 2SIMA 4MJUA 1E8VA 3TI4A 2VW0A 4YZ2A 1NCDN 1WCQA 1NCBN 1V3CA 4YZ1A 5JYYA 3TI3A 2C4LA 4HZYA 4J9TA 2HTWA 4FPOB 4XJAA 1XOGA 2YA4A 2HU0A 1S0IA 7NN9A 4YW1A 1EUSA 4SLIA 4GZTA 4XILA 1MS8A 4K1KA 2F28A 4X49A 2F29A 3GVKA 4XIKA 2F10A 3CL2A 2BF6A 2VK7A 4WA3A 2HTVA 2QWHA 1SNTA 3BEQA 3PJQA 4YZ3A 1NMBN 3SILA 1A4GA 3B69A 3H73A 1SLLA 2QWDA 2AGSA 1MS4A 1L7FA 4GJTA 1W21A 2F26A 1W8OA 2HTQA 1INWA 4FPYA 4XE9A 2F24A 1Z4VA 1DILA 3D12A 4YW2A 1Z4YA 5HUMA 2YA8A 1XOEA 2QWGA 4WA5A 2RKCA 4XOGA 4FPFA 4XJWA 3CKZA 2VSMA 4HZXA 3B7EA 1INYA 2YA5A 4MWXA 4XJ9A 4FOYA 3H71A 1V2IA 5HUNA 3TIBA 2CMLA 1NNBA 2HTUA 1MS9A 3NN9A 2F27A 2QWAA 3CL0A 4JF7A 4MWVA 4KS1A 2W5NA 1A4QA 2QWIA 1L7HA 2YDTA 4FZHA 4I00A 3O9JA 4MWRA 4CPYA 1SLIA 4MJVA 5HUKA 1IVEA 4UF7A 4H52A 2QWJA 5NN9A 4FJ6A 2QWCA 4M4NA 4CPZA 1F8BA 4MWJA 4XMIA 2YDPA 1Z4ZA 1NCCN 4K1JA 4QNPA 3H72A 2BZDA 2SLIA 5M1ZA 1DIMA 4XHBA 4XJZA 4XMAA 4YZ5A 1V0EA 1MR5A 3K38A 4FPCA 1IVCA 4CPLA 3SLIA 1NNAA 1N1TA 1NSBA 3OPZA 4QN4A 3TIAA 1IVBA 4QN3A 2QWEA 4FPLA 4K3YA 4BBWA 2QWBA 1MS5A 2VWDA 2HT7A 4KS2A 2HTYA 2A75A 3T1EA 4B7RA 4FP2A 1USXA 4CPNA 2C4AA 2W38A 4GZWA 4FPKA 5B2DA 3TI5A 4HZWA 2F25A 1USRA 2ZB6A 4K1HA 4NCSA 1B9TA 4GZOA 3TI8A 1W20A 3GVLA 1INGA 4YW3A 1N1SA 3TI6A 1N1VA 3INBA 2AH2A 1MS0A 1N1YA 1V0FA 1A14N 2F12A 1VCUA 4M3MA 3SALA 4MWUA 4B7JA 2BERA 2ZB5A 1S0JA 1V3EA 4HZVA 3SANA 2QWFA 4WA4A 4XHXA 3NSSA 1E8UA 2QWKA 1Z50A 4B7MA 3A72A 4B7NA 4X4AA 1MS1A 1KITA 4XYXA 4FPHA 4GZQA 4XIOA 3K3AA 5HX0A 3ALWA 3TICA 4GZSA 2F13A 1NMCA 2VSKA 2SILA 4GDIA 5HUGA 2YA7A 4FPGA 1IVDA 4MZAA 2B8HA 4X6KA 1F8EA 1Z4WA 4GZXA 1NCAN 1MS3A 1V3DA 2X9MA 1F8CA 3D11A 4QN7A 4YW4A 1W1XA 1Z4XA 4WEFA 2XZIA 2HT8A 4XJQA 2F11A 3W09A 2BATA 4FOWA 1NMAN 1B9SA 1V3BA 1B9VA 1F8DA 4GB1A 4QN6A 1NSDA 1INVA 6NN9A 4FOQA 4GZPA 2W20A 1MZ6A 2HTRA 4XJ8A 4FPJA 1MZ5A 4HIZA 4XJUA 1WCSA 4FVKA 2HT5A 1NN2A 3A71A 4MZEA 3K37A 2W5OA 4B7QA 3K39A 1NSCA 4KS4A 4KS3A 3CYEA 2AEPA 2YA6A 1EUTA 1VCJA 3O9KA 4MWQA 4GEZA 4MC7A 1V0ZA 4NC5A 4Q6KA 2VK6A 2VVZA 1W8NA 1INHA 4DGRA 4CPMA
chains in the Genus database with same CATH superfamily
1EURA 2AEQA 2HU4A 3HRPA 2IASA 3SOVA 4MWLA 3Q6TA 1INFA 4M4UA 4D52A 5GX4A 1NNCA 4UOUA 1BJIA 3GVJA 1SO7A 3S94A 2VW1A 1E8TA 3E5ZA 4HHQA 1ZI0A 4X47A 1IVGA 2ZWAA 4IQKA 2FHRA 3S8VA 1INXA 2IVZA 5B2CA 4L7CA 4MX0A 4XJRA 2XZJA 4KS5A 4YZ4A 4HZZA 2V91A 3ALXA 2XZKA 1EUUA 4AGIA 4FQ4A 2F0ZA 4MWYA 3DASA 2XCYA 4FPEA 4FOVA 4C1YB 2VW2A 2ISMA 4MWWA 1MWEA 4H53A 1IVFA 2JKBA 1CRUA 2DG0A 3I1CA 4GDJA 4K1IA 3WN7A 3K36A 1L7GA 1S18A 4C1YA 3L6VA 4WEGA 4AGTA 4NN9A 3JU4A 5F9TA 4CPOA 4FP3A 3WWAA 5FZNA 5FNTA 3FW0A 2FPCA 4M4VA 4QN5A 2IAUA 2VK5A 4YW5A 4GN8A 1W0OA 3H6JA 1K32A 4ASCA 4D8SA 1V04A 4HHOA 1W0PA 2SIMA 4MJUA 1E8VA 3TI4A 2VW0A 3SRGA 4YZ2A 1NCDN 2IAVA 1WCQA 2VPJA 1NCBN 1V3CA 4YZ1A 5JYYA 3TI3A 2C4LA 4HZYA 4J9TA 2OJHA 1N6DA 2HTWA 4FPOB 4XJAA 3ADEA 5D9BA 1XOGA 4R40A 2YA4A 2HU0A 1S0IA 2IAPA 4IN4A 7NN9A 4YW1A 1EUSA 2IAOA 4SLIA 4GZTA 1PJXA 2IATA 4XILA 1MS8A 4K1KA 4ZGCA 2F28A 4X49A 2F29A 1QBIA 4D4UA 3GVKA 4XIKA 2F10A 3CL2A 2IAQA 2BF6A 2VK7A 4WA3A 2HTVA 2QWHA 3NO0A 1SNTA 3BYCA 4CSDA 3BEQA 3PJQA 4XMBA 4YZ3A 3TC9A 1NMBN 5FZJA 1POOA 3SILA 4N1BA 1A4GA 3B69A 3H73A 1SLLA 2QWDA 5EO8A 4AHAA 5FNSA 2AGSA 1MS4A 3V65B 2GVWA 1L7FA 4GJTA 1W21A 2F26A 1W8OA 5D9DA 2HTQA 1INWA 2VAQA 4FPYA 4XE9A 3LI5A 2F24A 1Z4VA 1DILA 3D12A 4YW2A 1Z4YA 5HUMA 1QLGA 2YA8A 4A0PA 1XOEA 2W8BB 3S8ZA 2QWGA 4WA5A 2RKCA 4XOGA 3WDZA 1ZGKA 4FPFA 1H6LA 4XJWA 1N6EA 1C9UA 2P4OA 3CKZA 2VSMA 4HZXA 2W8BA 3B7EA 2WOZA 2Z32A 3SOQA 3VNGA 2GVUA 3FVZA 1INYA 1CRZA 2YA5A 1S1DA 2QE8A 5GX2A 4MWXA 2FLUX 3SOBB 4XJ9A 4FOYA 3H71A 1V2IA 1IJQA 5HUNA 4GN9A 3TIBA 2CMLA 1N7DA 3VNHA 4L7BA 1NNBA 2HTUA 1MS9A 2FP8A 3NN9A 2F27A 2QWAA 2POOA 3CL0A 4JF7A 4MWVA 3II7A 4KS1A 4L7DA 2W5NA 2XN4A 1A4QA 2H2NA 2QWIA 1L7HA 4GNCA 2IARA 2YDTA 4FZHA 4I00A 3O9JA 4MWRA 4CPYA 1SLIA 4MJVA 5HUKA 1IVEA 4UF7A 2IAWA 1C5KA 4H52A 3Q6KA 2QWJA 5NN9A 4FJ6A 2QWCA 4M4NA 4CPZA 1F8BA 4MWJA 4XMIA 2YDPA 3LI3A 1Z4ZA 2ZZKA 1NCCN 4AH4A 2DG1A 4K1JA 4QNPA 2DYHA 3H72A 2BZDA 2SLIA 5GX3A 5M1ZA 3A9GA 4CH9A 3A9HA 2DSOA 1DIMA 4XHBA 4XJZA 4XMAA 4O5SA 4YZ5A 1V0EA 1MR5A 3K38A 4FPCA 4ZY3A 3V64C 1IVCA 3P5BL 4CPLA 4IFNX 3SLIA 1NNAA 1N1TA 1NSBA 3S2KA 3WW9A 3OPZA 4QN4A 3HLIA 3TIAA 1IVBA 4QN3A 2QWEA 4FPLA 4K3YA 4BBWA 4PWZA 2QWBA 1MS5A 2GVXA 2VWDA 2HT7A 4KS2A 2HTYA 1CVMA 4HW6A 2A75A 3T1EA 3LI4A 4B7RA 4FP2A 3IAXA 1USXA 4CPNA 2C4AA 4ZLRA 2W38A 3G4HA 2FP9A 4GZWA 4IMBA 4FPKA 3KYAA 5B2DA 3TI5A 4HZWA 2F25A 1USRA 1X2RA 2ZB6A 4K1HA 4NCSA 1B9TA 4GZOA 1RWIA 3TI8A 1W20A 5FNUA 3GVLA 1INGA 4YW3A 3Q6PA 1CQ1A 5H47A 4D52C 1N1SA 3TI6A 1N1VA 3KGGA 3INBA 2AH2A 1MS0A 1N1YA 1V0FA 1A14N 4G3NA 5GX1A 2F12A 1VCUA 4M3MA 3SALA 3HLHA 4MWUA 4JMLA 4B7JA 2ZB5A 2BERA 4O5TA 3U0SA 1S0JA 1V3EA 5EO7A 4YY8A 4IFJA 5FNQA 4HZVA 5GTQA 3SANA 2QWFA 4WA4A 4XHXA 3NSSA 1E8UA 2QWKA 1Z50A 4GNAA 4B7MA 5F72C 5FNRA 2GVVA 3A72A 4B7NA 1IUCA 5GX5A 4X4AA 1MS1A 1KITA 4XYXA 1NPEA 4FPHA 3ZGCA 4GZQA 4XIOA 3K3AA 5HX0A 3ALWA 3TICA 4GZSA 1N6FA 2F13A 1NMCA 3AMRA 2G8SA 2VSKA 2SILA 4IFLX 4GDIA 5HUGA 2YA7A 4FPGA 1E1AA 1IVDA 4MZAA 2B8HA 4X6KA 1F8EA 1Z4WA 4GZXA 1IUBA 1NCAN 2ZW9A 1MS3A 3O4PA 1V3DA 2GHSA 2X9MA 1F8CA 3D11A 3ZGDA 2FPBA 4QN7A 5D9CA 4YW4A 1W1XA 1Z4XA 4WEFA 2XZIA 2HT8A 1OFZA 4XJQA 2F11A 2H2UA 4GNBA 3W09A 3SREA 5CGJA 2HQSA 2BATA 4FOWA 3G4EA 1NMAN 1B9SA 1V3BA 1B9VA 1SUUA 1RWLA 1F8DA 4GB1A 4QN6A 1NSDA 4CHBA 1INVA 6NN9A 4FOQA 4GZPA 1Q7FA 1X2JA 2W20A 1MZ6A 2HTRA 4XJ8A 3DR2A 4FPJA 1MZ5A 1U6DX 4HIZA 5FWWA 4XJUA 1WCSA 4FVKA 2HT5A 1NN2A 3A71A 4MZEA 3AMSA 3K37A 2W5OA 4B7QA 3K39A 1NSCA 2IAXA 4KS4A 4KS3A 3CYEA 2AEPA 2YA6A 1EUTA 4DG6A 1VCJA 4GN7A 1WP5A 3O9KA 4MWQA 4GEZA 4MC7A 1V0ZA 4Q1UA 4NC5A 4D52B 4IYGA 4Q6KA 3UC1A 2VK6A 2VVZA 1W8NA 1INHA 5EX7A 4DGRA 4CPMA 3V1SA
chains in the Genus database with same CATH topology
1EURA 2AEQA 2HU4A 4MWLA 1INFA 4M4UA 1NNCA 1BJIA 3GVJA 1SO7A 2VW1A 1E8TA 4X47A 1IVGA 2FHRA 1INXA 5B2CA 4MX0A 4XJRA 2XZJA 4KS5A 4YZ4A 4HZZA 3ALXA 2XZKA 1EUUA 4FQ4A 2F0ZA 4MWYA 2XCYA 4FPEA 4FOVA 2VW2A 4MWWA 1MWEA 4H53A 1IVFA 2JKBA 4GDJA 4K1IA 3K36A 1L7GA 1S18A 4WEGA 4NN9A 3JU4A 5F9TA 4CPOA 4FP3A 4M4VA 4QN5A 2VK5A 4YW5A 1W0OA 3H6JA 4D8SA 1W0PA 2SIMA 4MJUA 1E8VA 3TI4A 2VW0A 4YZ2A 1NCDN 1WCQA 1NCBN 1V3CA 4YZ1A 5JYYA 3TI3A 2C4LA 4HZYA 4J9TA 2HTWA 4FPOB 4XJAA 1XOGA 2YA4A 2HU0A 1S0IA 7NN9A 4YW1A 1EUSA 4SLIA 4GZTA 4XILA 1MS8A 4K1KA 2F28A 4X49A 2F29A 3GVKA 4XIKA 2F10A 3CL2A 2BF6A 2VK7A 4WA3A 2HTVA 2QWHA 1SNTA 3BEQA 3PJQA 4YZ3A 1NMBN 3SILA 1A4GA 3B69A 3H73A 1SLLA 2QWDA 2AGSA 1MS4A 1L7FA 4GJTA 1W21A 2F26A 1W8OA 2HTQA 1INWA 4FPYA 4XE9A 2F24A 1Z4VA 1DILA 3D12A 4YW2A 1Z4YA 5HUMA 2YA8A 1XOEA 2QWGA 4WA5A 2RKCA 4XOGA 4FPFA 4XJWA 3CKZA 2VSMA 4HZXA 3B7EA 1INYA 2YA5A 1S1DA 4MWXA 4XJ9A 4FOYA 3H71A 1V2IA 5HUNA 3TIBA 2CMLA 1NNBA 2HTUA 1MS9A 3NN9A 2F27A 2QWAA 3CL0A 4JF7A 4MWVA 4KS1A 2W5NA 1A4QA 2H2NA 2QWIA 1L7HA 2YDTA 4FZHA 4I00A 3O9JA 4MWRA 4CPYA 1SLIA 4MJVA 5HUKA 1IVEA 4UF7A 4H52A 2QWJA 5NN9A 4FJ6A 2QWCA 4M4NA 4CPZA 1F8BA 4MWJA 4XMIA 2YDPA 1Z4ZA 1NCCN 4K1JA 4QNPA 3H72A 2BZDA 2SLIA 5M1ZA 1DIMA 4XHBA 4XJZA 4XMAA 4YZ5A 1V0EA 1MR5A 3K38A 4FPCA 1IVCA 4CPLA 3SLIA 1NNAA 1N1TA 1NSBA 3OPZA 4QN4A 3TIAA 1IVBA 4QN3A 2QWEA 4FPLA 4K3YA 4BBWA 2QWBA 1MS5A 2VWDA 2HT7A 4KS2A 2HTYA 2A75A 3T1EA 4B7RA 4FP2A 1USXA 4CPNA 2C4AA 2W38A 4GZWA 4FPKA 5B2DA 3TI5A 4HZWA 2F25A 1USRA 2ZB6A 4K1HA 4NCSA 1B9TA 4GZOA 3TI8A 1W20A 3GVLA 1INGA 4YW3A 1N1SA 3TI6A 1N1VA 3INBA 2AH2A 1MS0A 1N1YA 1V0FA 1A14N 2F12A 1VCUA 4M3MA 3SALA 4MWUA 4B7JA 2BERA 2ZB5A 1S0JA 1V3EA 4HZVA 3SANA 2QWFA 4WA4A 4XHXA 3NSSA 1E8UA 2QWKA 1Z50A 4B7MA 3A72A 4B7NA 4X4AA 1MS1A 1KITA 4XYXA 4FPHA 4GZQA 4XIOA 3K3AA 5HX0A 3ALWA 3TICA 4GZSA 2F13A 1NMCA 2VSKA 2SILA 4GDIA 5HUGA 2YA7A 4FPGA 1IVDA 4MZAA 2B8HA 4X6KA 1F8EA 1Z4WA 4GZXA 1NCAN 1MS3A 1V3DA 2X9MA 1F8CA 3D11A 4QN7A 4YW4A 1W1XA 1Z4XA 4WEFA 2XZIA 2HT8A 4XJQA 2F11A 2H2UA 3W09A 2BATA 4FOWA 1NMAN 1B9SA 1V3BA 1B9VA 1F8DA 4GB1A 4QN6A 1NSDA 1INVA 6NN9A 4FOQA 4GZPA 2W20A 1MZ6A 2HTRA 4XJ8A 4FPJA 1MZ5A 4HIZA 4XJUA 1WCSA 4FVKA 2HT5A 1NN2A 3A71A 4MZEA 3K37A 2W5OA 4B7QA 3K39A 1NSCA 4KS4A 4KS3A 3CYEA 2AEPA 2YA6A 1EUTA 1VCJA 3O9KA 4MWQA 4GEZA 4MC7A 1V0ZA 4NC5A 4Q6KA 2VK6A 2VVZA 1W8NA 1INHA 4DGRA 4CPMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1EUR A;  2AEQ A;  2HU4 A;  4MWL A;  1INF A;  4M4U A;  1NNC A;  1BJI A;  3GVJ A;  1SO7 A;  2VW1 A;  1E8T A;  4X47 A;  1IVG A;  2FHR A;  1INX A;  5B2C A;  4MX0 A;  4XJR A;  2XZJ A;  4KS5 A;  4YZ4 A;  4HZZ A;  3ALX A;  2XZK A;  1EUU A;  4FQ4 A;  2F0Z A;  4MWY A;  2XCY A;  4FPE A;  4FOV A;  2VW2 A;  4MWW A;  1MWE A;  4H53 A;  1IVF A;  2JKB A;  4GDJ A;  4K1I A;  3K36 A;  1L7G A;  4WEG A;  4NN9 A;  3JU4 A;  5F9T A;  4CPO A;  4FP3 A;  4M4V A;  4QN5 A;  2VK5 A;  4YW5 A;  1W0O A;  3H6J A;  4D8S A;  1W0P A;  2SIM A;  4MJU A;  1E8V A;  3TI4 A;  2VW0 A;  4YZ2 A;  1NCD N;  1WCQ A;  1NCB N;  1V3C A;  4YZ1 A;  5JYY A;  3TI3 A;  2C4L A;  4HZY A;  4J9T A;  2HTW A;  4FPO B;  4XJA A;  1XOG A;  2YA4 A;  2HU0 A;  1S0I A;  7NN9 A;  4YW1 A;  1EUS A;  4SLI A;  4GZT A;  4XIL A;  1MS8 A;  4K1K A;  2F28 A;  4X49 A;  2F29 A;  3GVK A;  4XIK A;  2F10 A;  3CL2 A;  2BF6 A;  2VK7 A;  4WA3 A;  2HTV A;  2QWH A;  1SNT A;  3BEQ A;  3PJQ A;  4YZ3 A;  1NMB N;  3SIL A;  1A4G A;  3B69 A;  3H73 A;  1SLL A;  2QWD A;  2AGS A;  1MS4 A;  1L7F A;  4GJT A;  1W21 A;  2F26 A;  1W8O A;  2HTQ A;  1INW A;  4FPY A;  4XE9 A;  2F24 A;  1Z4V A;  1DIL A;  3D12 A;  4YW2 A;  1Z4Y A;  5HUM A;  2YA8 A;  1XOE A;  2QWG A;  4WA5 A;  2RKC A;  4XOG A;  4FPF A;  4XJW A;  3CKZ A;  2VSM A;  4HZX A;  3B7E A;  1INY A;  2YA5 A;  4MWX A;  4XJ9 A;  4FOY A;  3H71 A;  1V2I A;  5HUN A;  3TIB A;  2CML A;  1NNB A;  2HTU A;  1MS9 A;  3NN9 A;  2F27 A;  2QWA A;  3CL0 A;  4JF7 A;  4MWV A;  4KS1 A;  2W5N A;  1A4Q A;  2QWI A;  1L7H A;  2YDT A;  4FZH A;  4I00 A;  3O9J A;  4MWR A;  4CPY A;  1SLI A;  4MJV A;  5HUK A;  1IVE A;  4UF7 A;  4H52 A;  2QWJ A;  5NN9 A;  4FJ6 A;  2QWC A;  4M4N A;  4CPZ A;  1F8B A;  4MWJ A;  4XMI A;  2YDP A;  1Z4Z A;  1NCC N;  4K1J A;  4QNP A;  3H72 A;  2BZD A;  2SLI A;  5M1Z A;  1DIM A;  4XHB A;  4XJZ A;  4XMA A;  4YZ5 A;  1V0E A;  1MR5 A;  3K38 A;  4FPC A;  1IVC A;  4CPL A;  3SLI A;  1NNA A;  1N1T A;  1NSB A;  3OPZ A;  4QN4 A;  3TIA A;  1IVB A;  4QN3 A;  2QWE A;  4FPL A;  4K3Y A;  4BBW A;  2QWB A;  1MS5 A;  2VWD A;  2HT7 A;  4KS2 A;  2HTY A;  2A75 A;  3T1E A;  4B7R A;  4FP2 A;  1USX A;  4CPN A;  2C4A A;  2W38 A;  4GZW A;  4FPK A;  5B2D A;  3TI5 A;  4HZW A;  2F25 A;  1USR A;  2ZB6 A;  4K1H A;  4NCS A;  1B9T A;  4GZO A;  3TI8 A;  1W20 A;  3GVL A;  1ING A;  4YW3 A;  1N1S A;  3TI6 A;  1N1V A;  3INB A;  2AH2 A;  1MS0 A;  1N1Y A;  1V0F A;  1A14 N;  2F12 A;  1VCU A;  4M3M A;  3SAL A;  4MWU A;  4B7J A;  2BER A;  2ZB5 A;  1S0J A;  1V3E A;  4HZV A;  3SAN A;  2QWF A;  4WA4 A;  4XHX A;  3NSS A;  1E8U A;  2QWK A;  1Z50 A;  4B7M A;  3A72 A;  4B7N A;  4X4A A;  1MS1 A;  1KIT A;  4XYX A;  4FPH A;  4GZQ A;  4XIO A;  3K3A A;  5HX0 A;  3ALW A;  3TIC A;  4GZS A;  2F13 A;  1NMC A;  2VSK A;  2SIL A;  4GDI A;  5HUG A;  2YA7 A;  4FPG A;  1IVD A;  4MZA A;  2B8H A;  4X6K A;  1F8E A;  1Z4W A;  4GZX A;  1NCA N;  1MS3 A;  1V3D A;  2X9M A;  1F8C A;  3D11 A;  4QN7 A;  4YW4 A;  1W1X A;  1Z4X A;  4WEF A;  2XZI A;  2HT8 A;  4XJQ A;  2F11 A;  3W09 A;  2BAT A;  4FOW A;  1NMA N;  1B9S A;  1V3B A;  1B9V A;  1F8D A;  4GB1 A;  4QN6 A;  1NSD A;  1INV A;  6NN9 A;  4FOQ A;  4GZP A;  2W20 A;  1MZ6 A;  2HTR A;  4XJ8 A;  4FPJ A;  1MZ5 A;  4HIZ A;  4XJU A;  1WCS A;  4FVK A;  2HT5 A;  1NN2 A;  3A71 A;  4MZE A;  3K37 A;  2W5O A;  4B7Q A;  3K39 A;  1NSC A;  4KS4 A;  4KS3 A;  3CYE A;  2AEP A;  2YA6 A;  1EUT A;  1VCJ A;  3O9K A;  4MWQ A;  4GEZ A;  4MC7 A;  1V0Z A;  4NC5 A;  4Q6K A;  2VK6 A;  2VVZ A;  1W8N A;  1INH A;  4DGR A;  4CPM A; 
#chains in the Genus database with same CATH topology
 1EUR A;  2AEQ A;  2HU4 A;  3HRP A;  2IAS A;  3SOV A;  4MWL A;  3Q6T A;  1INF A;  4M4U A;  4D52 A;  5GX4 A;  1NNC A;  4UOU A;  1BJI A;  3GVJ A;  1SO7 A;  3S94 A;  2VW1 A;  1E8T A;  3E5Z A;  4HHQ A;  1ZI0 A;  4X47 A;  1IVG A;  2ZWA A;  4IQK A;  2FHR A;  3S8V A;  1INX A;  2IVZ A;  5B2C A;  4L7C A;  4MX0 A;  4XJR A;  2XZJ A;  4KS5 A;  4YZ4 A;  4HZZ A;  2V91 A;  3ALX A;  2XZK A;  1EUU A;  4AGI A;  4FQ4 A;  2F0Z A;  4MWY A;  3DAS A;  2XCY A;  4FPE A;  4FOV A;  4C1Y B;  2VW2 A;  2ISM A;  4MWW A;  1MWE A;  4H53 A;  1IVF A;  2JKB A;  1CRU A;  2DG0 A;  3I1C A;  4GDJ A;  4K1I A;  3WN7 A;  3K36 A;  1L7G A;  1S18 A;  4C1Y A;  3L6V A;  4WEG A;  4AGT A;  4NN9 A;  3JU4 A;  5F9T A;  4CPO A;  4FP3 A;  3WWA A;  5FZN A;  5FNT A;  3FW0 A;  2FPC A;  4M4V A;  4QN5 A;  2IAU A;  2VK5 A;  4YW5 A;  4GN8 A;  1W0O A;  3H6J A;  1K32 A;  4ASC A;  4D8S A;  1V04 A;  4HHO A;  1W0P A;  2SIM A;  4MJU A;  1E8V A;  3TI4 A;  2VW0 A;  3SRG A;  4YZ2 A;  1NCD N;  2IAV A;  1WCQ A;  2VPJ A;  1NCB N;  1V3C A;  4YZ1 A;  5JYY A;  3TI3 A;  2C4L A;  4HZY A;  4J9T A;  2OJH A;  1N6D A;  2HTW A;  4FPO B;  4XJA A;  3ADE A;  5D9B A;  1XOG A;  4R40 A;  2YA4 A;  2HU0 A;  1S0I A;  2IAP A;  4IN4 A;  7NN9 A;  4YW1 A;  1EUS A;  2IAO A;  4SLI A;  4GZT A;  1PJX A;  2IAT A;  4XIL A;  1MS8 A;  4K1K A;  4ZGC A;  2F28 A;  4X49 A;  2F29 A;  1QBI A;  4D4U A;  3GVK A;  4XIK A;  2F10 A;  3CL2 A;  2IAQ A;  2BF6 A;  2VK7 A;  4WA3 A;  2HTV A;  2QWH A;  3NO0 A;  1SNT A;  3BYC A;  4CSD A;  3BEQ A;  3PJQ A;  4XMB A;  4YZ3 A;  3TC9 A;  1NMB N;  5FZJ A;  1POO A;  3SIL A;  4N1B A;  1A4G A;  3B69 A;  3H73 A;  1SLL A;  2QWD A;  5EO8 A;  4AHA A;  5FNS A;  2AGS A;  1MS4 A;  3V65 B;  2GVW A;  1L7F A;  4GJT A;  1W21 A;  2F26 A;  1W8O A;  5D9D A;  2HTQ A;  1INW A;  2VAQ A;  4FPY A;  4XE9 A;  3LI5 A;  2F24 A;  1Z4V A;  1DIL A;  3D12 A;  4YW2 A;  1Z4Y A;  5HUM A;  1QLG A;  2YA8 A;  4A0P A;  1XOE A;  2W8B B;  3S8Z A;  2QWG A;  4WA5 A;  2RKC A;  4XOG A;  3WDZ A;  1ZGK A;  4FPF A;  1H6L A;  4XJW A;  1N6E A;  1C9U A;  2P4O A;  3CKZ A;  2VSM A;  4HZX A;  2W8B A;  3B7E A;  2WOZ A;  2Z32 A;  3SOQ A;  3VNG A;  2GVU A;  3FVZ A;  1INY A;  1CRZ A;  2YA5 A;  1S1D A;  2QE8 A;  5GX2 A;  4MWX A;  2FLU X;  3SOB B;  4XJ9 A;  4FOY A;  3H71 A;  1V2I A;  1IJQ A;  5HUN A;  4GN9 A;  3TIB A;  2CML A;  1N7D A;  3VNH A;  4L7B A;  1NNB A;  2HTU A;  1MS9 A;  2FP8 A;  3NN9 A;  2F27 A;  2QWA A;  2POO A;  3CL0 A;  4JF7 A;  4MWV A;  3II7 A;  4KS1 A;  4L7D A;  2W5N A;  2XN4 A;  1A4Q A;  2H2N A;  2QWI A;  1L7H A;  4GNC A;  2IAR A;  2YDT A;  4FZH A;  4I00 A;  3O9J A;  4MWR A;  4CPY A;  1SLI A;  4MJV A;  5HUK A;  1IVE A;  4UF7 A;  2IAW A;  1C5K A;  4H52 A;  3Q6K A;  2QWJ A;  5NN9 A;  4FJ6 A;  2QWC A;  4M4N A;  4CPZ A;  1F8B A;  4MWJ A;  4XMI A;  2YDP A;  3LI3 A;  1Z4Z A;  2ZZK A;  1NCC N;  4AH4 A;  2DG1 A;  4K1J A;  4QNP A;  2DYH A;  3H72 A;  2BZD A;  2SLI A;  5GX3 A;  5M1Z A;  3A9G A;  4CH9 A;  3A9H A;  2DSO A;  1DIM A;  4XHB A;  4XJZ A;  4XMA A;  4O5S A;  4YZ5 A;  1V0E A;  1MR5 A;  3K38 A;  4FPC A;  4ZY3 A;  3V64 C;  1IVC A;  3P5B L;  4CPL A;  4IFN X;  3SLI A;  1NNA A;  1N1T A;  1NSB A;  3S2K A;  3WW9 A;  3OPZ A;  4QN4 A;  3HLI A;  3TIA A;  1IVB A;  4QN3 A;  2QWE A;  4FPL A;  4K3Y A;  4BBW A;  4PWZ A;  2QWB A;  1MS5 A;  2GVX A;  2VWD A;  2HT7 A;  4KS2 A;  2HTY A;  1CVM A;  4HW6 A;  2A75 A;  3T1E A;  3LI4 A;  4B7R A;  4FP2 A;  3IAX A;  1USX A;  4CPN A;  2C4A A;  4ZLR A;  2W38 A;  3G4H A;  2FP9 A;  4GZW A;  4IMB A;  4FPK A;  3KYA A;  5B2D A;  3TI5 A;  4HZW A;  2F25 A;  1USR A;  1X2R A;  2ZB6 A;  4K1H A;  4NCS A;  1B9T A;  4GZO A;  1RWI A;  3TI8 A;  1W20 A;  5FNU A;  3GVL A;  1ING A;  4YW3 A;  3Q6P A;  1CQ1 A;  5H47 A;  4D52 C;  1N1S A;  3TI6 A;  1N1V A;  3KGG A;  3INB A;  2AH2 A;  1MS0 A;  1N1Y A;  1V0F A;  1A14 N;  4G3N A;  5GX1 A;  2F12 A;  1VCU A;  4M3M A;  3SAL A;  3HLH A;  4MWU A;  4JML A;  4B7J A;  2ZB5 A;  2BER A;  4O5T A;  3U0S A;  1S0J A;  1V3E A;  5EO7 A;  4YY8 A;  4IFJ A;  5FNQ A;  4HZV A;  5GTQ A;  3SAN A;  2QWF A;  4WA4 A;  4XHX A;  3NSS A;  1E8U A;  2QWK A;  1Z50 A;  4GNA A;  4B7M A;  5F72 C;  5FNR A;  2GVV A;  3A72 A;  4B7N A;  1IUC A;  5GX5 A;  4X4A A;  1MS1 A;  1KIT A;  4XYX A;  1NPE A;  4FPH A;  3ZGC A;  4GZQ A;  4XIO A;  3K3A A;  5HX0 A;  3ALW A;  3TIC A;  4GZS A;  1N6F A;  2F13 A;  1NMC A;  3AMR A;  2G8S A;  2VSK A;  2SIL A;  4IFL X;  4GDI A;  5HUG A;  2YA7 A;  4FPG A;  1E1A A;  1IVD A;  4MZA A;  2B8H A;  4X6K A;  1F8E A;  1Z4W A;  4GZX A;  1IUB A;  1NCA N;  2ZW9 A;  1MS3 A;  3O4P A;  1V3D A;  2GHS A;  2X9M A;  1F8C A;  3D11 A;  3ZGD A;  2FPB A;  4QN7 A;  5D9C A;  4YW4 A;  1W1X A;  1Z4X A;  4WEF A;  2XZI A;  2HT8 A;  1OFZ A;  4XJQ A;  2F11 A;  2H2U A;  4GNB A;  3W09 A;  3SRE A;  5CGJ A;  2HQS A;  2BAT A;  4FOW A;  3G4E A;  1NMA N;  1B9S A;  1V3B A;  1B9V A;  1SUU A;  1RWL A;  1F8D A;  4GB1 A;  4QN6 A;  1NSD A;  4CHB A;  1INV A;  6NN9 A;  4FOQ A;  4GZP A;  1Q7F A;  1X2J A;  2W20 A;  1MZ6 A;  2HTR A;  4XJ8 A;  3DR2 A;  4FPJ A;  1MZ5 A;  1U6D X;  4HIZ A;  5FWW A;  4XJU A;  1WCS A;  4FVK A;  2HT5 A;  1NN2 A;  3A71 A;  4MZE A;  3AMS A;  3K37 A;  2W5O A;  4B7Q A;  3K39 A;  1NSC A;  2IAX A;  4KS4 A;  4KS3 A;  3CYE A;  2AEP A;  2YA6 A;  1EUT A;  4DG6 A;  1VCJ A;  4GN7 A;  1WP5 A;  3O9K A;  4MWQ A;  4GEZ A;  4MC7 A;  1V0Z A;  4Q1U A;  4NC5 A;  4D52 B;  4IYG A;  4Q6K A;  3UC1 A;  2VK6 A;  2VVZ A;  1W8N A;  1INH A;  5EX7 A;  4DGR A;  4CPM A;  3V1S A; 
#chains in the Genus database with same CATH homology
 1EUR A;  2AEQ A;  2HU4 A;  4MWL A;  1INF A;  4M4U A;  1NNC A;  1BJI A;  3GVJ A;  1SO7 A;  2VW1 A;  1E8T A;  4X47 A;  1IVG A;  2FHR A;  1INX A;  5B2C A;  4MX0 A;  4XJR A;  2XZJ A;  4KS5 A;  4YZ4 A;  4HZZ A;  3ALX A;  2XZK A;  1EUU A;  4FQ4 A;  2F0Z A;  4MWY A;  2XCY A;  4FPE A;  4FOV A;  2VW2 A;  4MWW A;  1MWE A;  4H53 A;  1IVF A;  2JKB A;  4GDJ A;  4K1I A;  3K36 A;  1L7G A;  1S18 A;  4WEG A;  4NN9 A;  3JU4 A;  5F9T A;  4CPO A;  4FP3 A;  4M4V A;  4QN5 A;  2VK5 A;  4YW5 A;  1W0O A;  3H6J A;  4D8S A;  1W0P A;  2SIM A;  4MJU A;  1E8V A;  3TI4 A;  2VW0 A;  4YZ2 A;  1NCD N;  1WCQ A;  1NCB N;  1V3C A;  4YZ1 A;  5JYY A;  3TI3 A;  2C4L A;  4HZY A;  4J9T A;  2HTW A;  4FPO B;  4XJA A;  1XOG A;  2YA4 A;  2HU0 A;  1S0I A;  7NN9 A;  4YW1 A;  1EUS A;  4SLI A;  4GZT A;  4XIL A;  1MS8 A;  4K1K A;  2F28 A;  4X49 A;  2F29 A;  3GVK A;  4XIK A;  2F10 A;  3CL2 A;  2BF6 A;  2VK7 A;  4WA3 A;  2HTV A;  2QWH A;  1SNT A;  3BEQ A;  3PJQ A;  4YZ3 A;  1NMB N;  3SIL A;  1A4G A;  3B69 A;  3H73 A;  1SLL A;  2QWD A;  2AGS A;  1MS4 A;  1L7F A;  4GJT A;  1W21 A;  2F26 A;  1W8O A;  2HTQ A;  1INW A;  4FPY A;  4XE9 A;  2F24 A;  1Z4V A;  1DIL A;  3D12 A;  4YW2 A;  1Z4Y A;  5HUM A;  2YA8 A;  1XOE A;  2QWG A;  4WA5 A;  2RKC A;  4XOG A;  4FPF A;  4XJW A;  3CKZ A;  2VSM A;  4HZX A;  3B7E A;  1INY A;  2YA5 A;  1S1D A;  4MWX A;  4XJ9 A;  4FOY A;  3H71 A;  1V2I A;  5HUN A;  3TIB A;  2CML A;  1NNB A;  2HTU A;  1MS9 A;  3NN9 A;  2F27 A;  2QWA A;  3CL0 A;  4JF7 A;  4MWV A;  4KS1 A;  2W5N A;  1A4Q A;  2H2N A;  2QWI A;  1L7H A;  2YDT A;  4FZH A;  4I00 A;  3O9J A;  4MWR A;  4CPY A;  1SLI A;  4MJV A;  5HUK A;  1IVE A;  4UF7 A;  4H52 A;  2QWJ A;  5NN9 A;  4FJ6 A;  2QWC A;  4M4N A;  4CPZ A;  1F8B A;  4MWJ A;  4XMI A;  2YDP A;  1Z4Z A;  1NCC N;  4K1J A;  4QNP A;  3H72 A;  2BZD A;  2SLI A;  5M1Z A;  1DIM A;  4XHB A;  4XJZ A;  4XMA A;  4YZ5 A;  1V0E A;  1MR5 A;  3K38 A;  4FPC A;  1IVC A;  4CPL A;  3SLI A;  1NNA A;  1N1T A;  1NSB A;  3OPZ A;  4QN4 A;  3TIA A;  1IVB A;  4QN3 A;  2QWE A;  4FPL A;  4K3Y A;  4BBW A;  2QWB A;  1MS5 A;  2VWD A;  2HT7 A;  4KS2 A;  2HTY A;  2A75 A;  3T1E A;  4B7R A;  4FP2 A;  1USX A;  4CPN A;  2C4A A;  2W38 A;  4GZW A;  4FPK A;  5B2D A;  3TI5 A;  4HZW A;  2F25 A;  1USR A;  2ZB6 A;  4K1H A;  4NCS A;  1B9T A;  4GZO A;  3TI8 A;  1W20 A;  3GVL A;  1ING A;  4YW3 A;  1N1S A;  3TI6 A;  1N1V A;  3INB A;  2AH2 A;  1MS0 A;  1N1Y A;  1V0F A;  1A14 N;  2F12 A;  1VCU A;  4M3M A;  3SAL A;  4MWU A;  4B7J A;  2BER A;  2ZB5 A;  1S0J A;  1V3E A;  4HZV A;  3SAN A;  2QWF A;  4WA4 A;  4XHX A;  3NSS A;  1E8U A;  2QWK A;  1Z50 A;  4B7M A;  3A72 A;  4B7N A;  4X4A A;  1MS1 A;  1KIT A;  4XYX A;  4FPH A;  4GZQ A;  4XIO A;  3K3A A;  5HX0 A;  3ALW A;  3TIC A;  4GZS A;  2F13 A;  1NMC A;  2VSK A;  2SIL A;  4GDI A;  5HUG A;  2YA7 A;  4FPG A;  1IVD A;  4MZA A;  2B8H A;  4X6K A;  1F8E A;  1Z4W A;  4GZX A;  1NCA N;  1MS3 A;  1V3D A;  2X9M A;  1F8C A;  3D11 A;  4QN7 A;  4YW4 A;  1W1X A;  1Z4X A;  4WEF A;  2XZI A;  2HT8 A;  4XJQ A;  2F11 A;  2H2U A;  3W09 A;  2BAT A;  4FOW A;  1NMA N;  1B9S A;  1V3B A;  1B9V A;  1F8D A;  4GB1 A;  4QN6 A;  1NSD A;  1INV A;  6NN9 A;  4FOQ A;  4GZP A;  2W20 A;  1MZ6 A;  2HTR A;  4XJ8 A;  4FPJ A;  1MZ5 A;  4HIZ A;  4XJU A;  1WCS A;  4FVK A;  2HT5 A;  1NN2 A;  3A71 A;  4MZE A;  3K37 A;  2W5O A;  4B7Q A;  3K39 A;  1NSC A;  4KS4 A;  4KS3 A;  3CYE A;  2AEP A;  2YA6 A;  1EUT A;  1VCJ A;  3O9K A;  4MWQ A;  4GEZ A;  4MC7 A;  1V0Z A;  4NC5 A;  4Q6K A;  2VK6 A;  2VVZ A;  1W8N A;  1INH A;  4DGR A;  4CPM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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