2QWFA

The x-ray structure of a complex of n-acetyl-4-guanidino-6-methyl(propyl)carboxamide-4,5-dihydro-2h-pyran-2-carboxylic acid and a drug resistant variant r292k of tern n9 influenza virus neuraminidase
Total Genus 113
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
388
structure length
388
Chain Sequence
RDFNNLTKGLCTINSWHIYGKDNAVRIGEDSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKTRMSICISGPNNNASAVIWYNRRPVTEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPAETRIYYFKEGKILKWEPLAGTAKHIEECSCYGERAEITCTCKDNWQGSNRPVIRIDPVAMTHTSQYICSPVLTDNPRPNDPTVGKCNDPYPGNNNNGVKGFSYLDGVNTWLGRTISIASRSGYEMLKVPNALTDDKSKPTQGQTIVLNTDWSGYSGSFMDYWAEGECYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWDWPDGAKIEYFL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords NEURAMINIDASE
total genus 113
structure length 388
sequence length 388
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 1998-04-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00064 Neur Neuraminidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 2qwfA00
4XYXA 4MX0A 4CPNA 4K1JA 4XILA 3SLIA 1INHA 1NNCA 2ZB6A 4FZHA 1F8DA 1INXA 4MWUA 1MS4A 4CPLA 2ZB5A 4X6KA 4FOWA 4GDIA 2HTRA 4B7NA 3GVKA 1SO7A 1DILA 4Q6KA 4YZ4A 2YA7A 7NN9A 4FPKA 1S0JA 4MWWA 2QWAA 4D8SA 2F28A 2VK6A 2VWDA 3SANA 1Z50A 3K38A 4MWQA 3A72A 4B7MA 4QN7A 2VW2A 4XE9A 2QWCA 2BF6A 2HU4A 1NN2A 4WEGA 4I00A 4K1KA 1XOGA 4MZEA 4SLIA 1B9VA 5HUKA 4GZPA 1NMCA 4FPEA 4HIZA 4GJTA 2F12A 3O9JA 1IVGA 4FPCA 4M3MA 4CPYA 4M4UA 3B7EA 1NMBN 3TIBA 3GVLA 3ALWA 4WEFA 3TIAA 2HU0A 1V3DA 1Z4WA 3SILA 1USXA 2HTYA 4K3YA 4HZXA 2QWIA 1L7FA 5HX0A 4YZ3A 2W5NA 1NCAN 2HT7A 5B2DA 3TI5A 1MS3A 2SLIA 2F29A 4FOQA 4KS2A 4MWLA 3BEQA 1A14N 3H73A 4QN3A 4MC7A 2QWDA 2XZIA 2VK7A 5B2CA 4DGRA 2BERA 1V2IA 4X4AA 4KS4A 2QWJA 2VW1A 4FJ6A 4GDJA 1B9SA 4XMAA 2W38A 4FPFA 4BBWA 2F25A 4XJRA 2B8HA 1W0OA 2BATA 4H52A 4M4VA 4FPHA 2F10A 4XHXA 4YZ2A 1N1TA 4XJWA 4KS3A 1S0IA 2HT5A 2YA8A 4YW2A 4XJ9A 1NMAN 1NNBA 1INYA 4NN9A 4MWYA 1NSBA 3D12A 3JU4A 2HTQA 4FOYA 1IVCA 4YZ5A 1W0PA 2VW0A 3W09A 1V0EA 2AGSA 2HTVA 4FQ4A 4MJVA 1MS8A 2HTUA 2VSMA 4B7RA 4MWRA 1USRA 1EUSA 4XIKA 4FPOB 1N1VA 4MJUA 1E8UA 2XZJA 1F8CA 1NCDN 4YW5A 3K37A 1L7HA 2FHRA 2W20A 3PJQA 1A4QA 4FOVA 1BJIA 4KS1A 2QWHA 1MZ6A 3K39A 4GZTA 4HZVA 2XCYA 1F8EA 4XJ8A 1E8TA 1IVFA 1W21A 3CL2A 3K3AA 2A75A 4QN4A 2AEQA 1VCUA 4FPGA 1NCCN 4GZWA 2AH2A 4NCSA 4K1HA 4MWVA 3TICA 4CPMA 3SALA 3CL0A 2YA4A 4MWXA 5F9TA 2X9MA 1INVA 1Z4ZA 4UF7A 4YZ1A 4CPOA 2F0ZA 2HT8A 2RKCA 2QWEA 4XOGA 4WA3A 4GEZA 3TI3A 3T1EA 1F8BA 1NSCA 3NN9A 4WA4A 1Z4XA 2QWGA 1EUTA 3GVJA 4GZSA 1Z4VA 1INFA 1DIMA 2SIMA 3INBA 4KS5A 4X49A 3D11A 4J9TA 4B7QA 4QN5A 1W1XA 1IVDA 4XHBA 2F27A 2W5OA 5JYYA 2YDTA 1EURA 1SLIA 4X47A 2BZDA 1WCQA 2VSKA 1IVEA 2VK5A 3TI4A 1MS5A 4K1IA 4MWJA 4MZAA 3O9KA 4QN6A 1L7GA 1N1YA 1XOEA 1V3CA 1IVBA 1NSDA 4FPLA 3CYEA 6NN9A 4GB1A 3B69A 1W8OA 2YDPA 5M1ZA 2QWBA 2YA5A 4GZOA 4M4NA 1SNTA 4FP2A 4XMIA 1INWA 2F11A 1NNAA 1VCJA 2C4LA 3H6JA 2VVZA 1KITA 4HZWA 2F24A 4B7JA 4FVKA 5HUGA 4XJUA 4HZYA 3NSSA 3OPZA 3A71A 2CMLA 4XIOA 1W8NA 5HUMA 1MS0A 4YW1A 1MS1A 1V0ZA 3TI8A 4GZXA 4YW3A 1E8VA 5HUNA 4FPYA 1W20A 5NN9A 2QWFA 3H72A 2QWKA 1MS9A 1V3BA 1MWEA 4XJAA 4XJZA 4QNPA 2XZKA 4YW4A 2SILA 2YA6A 3CKZA 1SLLA 4WA5A 2JKBA 2C4AA 4FP3A 1INGA 2AEPA 1B9TA 3H71A 1N1SA 1WCSA 4XJQA 4JF7A 1MZ5A 1Z4YA 1EUUA 4HZZA 2F26A 1NCBN 1MR5A 4FPJA 3K36A 4H53A 2F13A 1V3EA 3TI6A 1V0FA 3ALXA 2HTWA 4GZQA 4CPZA 4NC5A 1A4GA
chains in the Genus database with same CATH superfamily
4XYXA 4HW6A 4MX0A 4CPNA 4K1JA 4XILA 3SLIA 3O4PA 1INHA 1NNCA 4AGTA 2ZB6A 4FZHA 3ADEA 1F8DA 1INXA 1N6DA 4MWUA 1MS4A 4CPLA 2W8BB 2ZB5A 2W8BA 4X6KA 4FOWA 3HRPA 4GDIA 2HTRA 4B7NA 3GVKA 1SO7A 1DILA 4Q6KA 4YZ4A 2YA7A 3TC9A 4UOUA 7NN9A 2GHSA 5H47A 2IATA 3P5BL 4FPKA 1NPEA 1S0JA 1PJXA 4MWWA 2QWAA 1CRUA 4D8SA 2F28A 2VK6A 2VWDA 4IFLX 3SANA 1Z50A 2FPBA 3K38A 4AH4A 4MWQA 3A72A 2IVZA 4B7MA 4QN7A 2VW2A 5GX4A 1C9UA 4XE9A 3U0SA 2QWCA 1S1DA 2BF6A 2H2NA 2HU4A 1NN2A 4WEGA 4I00A 4K1KA 1XOGA 4MZEA 4SLIA 4CPZA 3DR2A 1B9VA 5HUKA 1RWLA 5GX5A 4GZPA 1NMCA 5FNTA 3SRGA 4FPEA 4HIZA 4GJTA 4ZLRA 2F12A 3UC1A 3O9JA 1IVGA 4FPCA 4M3MA 4CPYA 4M4UA 3B7EA 1NMBN 3TIBA 3GVLA 3SOVA 3ALWA 2H2UA 1X2JA 4WEFA 3TIAA 2HU0A 1V3DA 4R40A 1Z4WA 4N1BA 3V65B 3SILA 4O5SA 4GN8A 3I1CA 1USXA 2HTYA 3BYCA 3WWAA 4K3YA 3S2KA 3G4EA 5EO8A 1QLGA 3NO0A 3S8ZA 4CSDA 4HZXA 2QWIA 1L7FA 5HX0A 4YZ3A 4GNCA 2W5NA 1NCAN 2HT7A 3KGGA 4IN4A 5B2DA 3TI5A 1MS3A 5D9BA 1QBIA 2SLIA 4DG6A 2F29A 4FOQA 4KS2A 2IAOA 3G4HA 4MWLA 2ZW9A 3BEQA 1A14N 3H73A 4O5TA 4QN3A 2G8SA 1ZGKA 4MC7A 2QWDA 2XZIA 2VK7A 3S94A 5B2CA 2OJHA 3L6VA 3FVZA 2BERA 4DGRA 1V2IA 4X4AA 4KS4A 2QWJA 1N7DA 2VW1A 4FJ6A 4GDJA 4AGIA 1B9SA 4XMAA 2W38A 4FPFA 3AMRA 4BBWA 2F25A 4XJRA 2B8HA 2XN4A 1W0OA 2BATA 4H52A 4M4VA 3FW0A 4FPHA 2F10A 4XHXA 4YZ2A 1N1TA 4XJWA 4KS3A 1S0IA 2HT5A 2YA8A 4CH9A 4YW2A 1E1AA 4XJ9A 1NMAN 5GX3A 1NNBA 1INYA 4NN9A 4MWYA 1NSBA 3D12A 3JU4A 1CQ1A 2HTQA 5EO7A 5FZNA 4FOYA 5FNRA 3ZGCA 1IVCA 4YZ5A 1W0PA 2VW0A 3W09A 5D9DA 4IQKA 1V0EA 2AGSA 2HTVA 4FQ4A 4MJVA 3V64C 3AMSA 1MS8A 2HTUA 4D4UA 5GX1A 2VSMA 4B7RA 3SOBB 4MWRA 1USRA 3S8VA 1EUSA 4XIKA 1OFZA 3KYAA 2DG1A 4FPOB 1N1VA 4MJUA 4ZGCA 5D9CA 1E8UA 2XZJA 3WDZA 2GVWA 1F8CA 1NCDN 1U6DX 3K37A 1L7HA 4YW5A 1C5KA 2FHRA 2W20A 3PJQA 4GN9A 1A4QA 4FOVA 1BJIA 2Z32A 2QWHA 4KS1A 1MZ6A 3K39A 4GZTA 4HZVA 2XCYA 1F8EA 1N6FA 4XJ8A 4YY8A 1E8TA 1IVFA 2DG0A 1W21A 3CL2A 3K3AA 2A75A 4QN4A 2AEQA 3VNGA 1VCUA 4FPGA 1CRZA 3II7A 2P4OA 1NCCN 4GZWA 4ASCA 2FLUX 2AH2A 2IAUA 4HHQA 4NCSA 5GTQA 4K1HA 4MWVA 3TICA 4CPMA 3SALA 4IFJA 4CHBA 3CL0A 3HLIA 2HQSA 4L7CA 2YA4A 2VPJA 4MWXA 5F9TA 2X9MA 1INVA 1Z4ZA 4ZY3A 4UF7A 4YZ1A 5GX2A 4CPOA 2F0ZA 2HT8A 2RKCA 2QWEA 5FZJA 4XOGA 2FP9A 2GVVA 4WA3A 4GEZA 1WP5A 4G3NA 3TI3A 3T1EA 3DASA 1F8BA 1NSCA 3NN9A 1H6LA 4WA4A 1Z4XA 5FNUA 2QWGA 1V04A 3VNHA 1EUTA 2ISMA 3GVJA 3HLHA 4GZSA 1Z4VA 1INFA 1DIMA 2SIMA 3INBA 5CGJA 4KS5A 4X49A 2VAQA 3D11A 4J9TA 4B7QA 4QN5A 1W1XA 1IVDA 4XHBA 4Q1UA 2F27A 2W5OA 5JYYA 2YDTA 3IAXA 4IMBA 1EURA 1SLIA 2IAVA 4AHAA 4X47A 4GNAA 3WW9A 2BZDA 1WCQA 5EX7A 4L7BA 2VSKA 1IVEA 2VK5A 3TI4A 1MS5A 4K1IA 4MWJA 4MZAA 3O9KA 4QN6A 1L7GA 1N1YA 1XOEA 2DSOA 1V3CA 1IVBA 1NSDA 4FPLA 1K32A 1SUUA 3SREA 3CYEA 6NN9A 4GB1A 4IYGA 3B69A 1W8OA 2YDPA 5M1ZA 2FP8A 2IASA 2QWBA 2YA5A 2FPCA 4GZOA 4M4NA 1SNTA 4FP2A 4XMIA 1INWA 3WN7A 2F11A 1NNAA 1VCJA 3SOQA 4IFNX 2C4LA 3H6JA 2VVZA 4A0PA 1KITA 3Q6TA 4HZWA 1X2RA 2F24A 4B7JA 4FVKA 2IAQA 5HUGA 4XJUA 3ZGDA 2GVUA 4HZYA 1IJQA 3NSSA 3OPZA 3A71A 2CMLA 2IAXA 4XIOA 2GVXA 1W8NA 5FNSA 5HUMA 1MS0A 4YW1A 4GNBA 2ZZKA 1N6EA 1S18A 1MS1A 4D52B 1V0ZA 4D52A 3TI8A 4GZXA 4YW3A 3E5ZA 4JMLA 1E8VA 5HUNA 4GN7A 4FPYA 2IAPA 1W20A 2QE8A 5NN9A 2QWFA 1Q7FA 3H72A 2QWKA 3A9GA 1MS9A 1ZI0A 3LI4A 1V3BA 5FNQA 1MWEA 2WOZA 4XJAA 4PWZA 3LI3A 4XJZA 1RWIA 4QNPA 2XZKA 4YW4A 2SILA 2YA6A 3CKZA 1SLLA 2IARA 4WA5A 1POOA 2JKBA 2C4AA 4L7DA 4FP3A 3Q6PA 1INGA 2AEPA 4D52C 1B9TA 3H71A 1N1SA 1WCSA 4XJQA 4JF7A 1MZ5A 5F72C 1Z4YA 1EUUA 2IAWA 3Q6KA 4HZZA 2F26A 2DYHA 3V1SA 2POOA 4XMBA 1NCBN 1MR5A 4FPJA 3K36A 4H53A 1CVMA 5FWWA 2F13A 1V3EA 3TI6A 1V0FA 3A9HA 2V91A 3ALXA 2HTWA 3LI5A 1IUCA 4GZQA 4C1YB 4C1YA 2ZWAA 4HHOA 1IUBA 4NC5A 1A4GA
chains in the Genus database with same CATH topology
4XYXA 4MX0A 4CPNA 4K1JA 4XILA 3SLIA 1INHA 1NNCA 2ZB6A 4FZHA 1F8DA 1INXA 4MWUA 1MS4A 4CPLA 2ZB5A 4X6KA 4FOWA 4GDIA 2HTRA 4B7NA 3GVKA 1SO7A 1DILA 4Q6KA 4YZ4A 2YA7A 7NN9A 4FPKA 1S0JA 4MWWA 2QWAA 4D8SA 2F28A 2VK6A 2VWDA 3SANA 1Z50A 3K38A 4MWQA 3A72A 4B7MA 4QN7A 2VW2A 4XE9A 2QWCA 1S1DA 2BF6A 2H2NA 2HU4A 1NN2A 4WEGA 4I00A 4K1KA 1XOGA 4MZEA 4SLIA 1B9VA 5HUKA 4GZPA 1NMCA 4FPEA 4HIZA 4GJTA 2F12A 3O9JA 1IVGA 4FPCA 4M3MA 4CPYA 4M4UA 3B7EA 1NMBN 3TIBA 3GVLA 3ALWA 2H2UA 4WEFA 3TIAA 2HU0A 1V3DA 1Z4WA 3SILA 1USXA 2HTYA 4K3YA 4HZXA 2QWIA 1L7FA 5HX0A 4YZ3A 2W5NA 1NCAN 2HT7A 5B2DA 3TI5A 1MS3A 2SLIA 2F29A 4FOQA 4KS2A 4MWLA 3BEQA 1A14N 3H73A 4QN3A 4MC7A 2QWDA 2XZIA 2VK7A 5B2CA 4DGRA 2BERA 1V2IA 4X4AA 4KS4A 2QWJA 2VW1A 4FJ6A 4GDJA 1B9SA 4XMAA 2W38A 4FPFA 4BBWA 2F25A 4XJRA 2B8HA 1W0OA 2BATA 4H52A 4M4VA 4FPHA 2F10A 4XHXA 4YZ2A 1N1TA 4XJWA 4KS3A 1S0IA 2HT5A 2YA8A 4YW2A 4XJ9A 1NMAN 1NNBA 1INYA 4NN9A 4MWYA 1NSBA 3D12A 3JU4A 2HTQA 4FOYA 1IVCA 4YZ5A 1W0PA 2VW0A 3W09A 1V0EA 2AGSA 2HTVA 4FQ4A 4MJVA 1MS8A 2HTUA 2VSMA 4B7RA 4MWRA 1USRA 1EUSA 4XIKA 4FPOB 1N1VA 4MJUA 1E8UA 2XZJA 1F8CA 1NCDN 4YW5A 3K37A 1L7HA 2FHRA 2W20A 3PJQA 1A4QA 4FOVA 1BJIA 4KS1A 2QWHA 1MZ6A 3K39A 4GZTA 4HZVA 2XCYA 1F8EA 4XJ8A 1E8TA 1IVFA 1W21A 3CL2A 3K3AA 2A75A 4QN4A 2AEQA 1VCUA 4FPGA 1NCCN 4GZWA 2AH2A 4NCSA 4K1HA 4MWVA 3TICA 4CPMA 3SALA 3CL0A 2YA4A 4MWXA 5F9TA 2X9MA 1INVA 1Z4ZA 4UF7A 4YZ1A 4CPOA 2F0ZA 2HT8A 2RKCA 2QWEA 4XOGA 4WA3A 4GEZA 3TI3A 3T1EA 1F8BA 1NSCA 3NN9A 4WA4A 1Z4XA 2QWGA 1EUTA 3GVJA 4GZSA 1Z4VA 1INFA 1DIMA 2SIMA 3INBA 4KS5A 4X49A 3D11A 4J9TA 4B7QA 4QN5A 1W1XA 1IVDA 4XHBA 2F27A 2W5OA 5JYYA 2YDTA 1EURA 1SLIA 4X47A 2BZDA 1WCQA 2VSKA 1IVEA 2VK5A 3TI4A 1MS5A 4K1IA 4MWJA 4MZAA 3O9KA 4QN6A 1L7GA 1N1YA 1XOEA 1V3CA 1IVBA 1NSDA 4FPLA 3CYEA 6NN9A 4GB1A 3B69A 1W8OA 2YDPA 5M1ZA 2QWBA 2YA5A 4GZOA 4M4NA 1SNTA 4FP2A 4XMIA 1INWA 2F11A 1NNAA 1VCJA 2C4LA 3H6JA 2VVZA 1KITA 4HZWA 2F24A 4B7JA 4FVKA 5HUGA 4XJUA 4HZYA 3NSSA 3OPZA 3A71A 2CMLA 4XIOA 1W8NA 5HUMA 1MS0A 4YW1A 1S18A 1MS1A 1V0ZA 3TI8A 4GZXA 4YW3A 1E8VA 5HUNA 4FPYA 1W20A 5NN9A 2QWFA 3H72A 2QWKA 1MS9A 1V3BA 1MWEA 4XJAA 4XJZA 4QNPA 2XZKA 4YW4A 2SILA 2YA6A 3CKZA 1SLLA 4WA5A 2JKBA 2C4AA 4FP3A 1INGA 2AEPA 1B9TA 3H71A 1N1SA 1WCSA 4XJQA 4JF7A 1MZ5A 1Z4YA 1EUUA 4HZZA 2F26A 1NCBN 1MR5A 4FPJA 3K36A 4H53A 2F13A 1V3EA 3TI6A 1V0FA 3ALXA 2HTWA 4GZQA 4CPZA 4NC5A 1A4GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XYX A;  4MX0 A;  4CPN A;  4K1J A;  4XIL A;  3SLI A;  1INH A;  1NNC A;  2ZB6 A;  4FZH A;  1F8D A;  1INX A;  4MWU A;  1MS4 A;  4CPL A;  2ZB5 A;  4X6K A;  4FOW A;  4GDI A;  2HTR A;  4B7N A;  3GVK A;  1SO7 A;  1DIL A;  4Q6K A;  4YZ4 A;  2YA7 A;  7NN9 A;  4FPK A;  1S0J A;  4MWW A;  2QWA A;  4D8S A;  2F28 A;  2VK6 A;  2VWD A;  3SAN A;  1Z50 A;  3K38 A;  4MWQ A;  3A72 A;  4B7M A;  4QN7 A;  2VW2 A;  4XE9 A;  2QWC A;  2BF6 A;  2HU4 A;  1NN2 A;  4WEG A;  4I00 A;  4K1K A;  1XOG A;  4MZE A;  4SLI A;  1B9V A;  5HUK A;  4GZP A;  1NMC A;  4FPE A;  4HIZ A;  4GJT A;  2F12 A;  3O9J A;  1IVG A;  4FPC A;  4M3M A;  4CPY A;  4M4U A;  3B7E A;  1NMB N;  3TIB A;  3GVL A;  3ALW A;  4WEF A;  3TIA A;  2HU0 A;  1V3D A;  1Z4W A;  3SIL A;  1USX A;  2HTY A;  4K3Y A;  4HZX A;  2QWI A;  1L7F A;  5HX0 A;  4YZ3 A;  2W5N A;  1NCA N;  2HT7 A;  5B2D A;  3TI5 A;  1MS3 A;  2SLI A;  2F29 A;  4FOQ A;  4KS2 A;  4MWL A;  3BEQ A;  1A14 N;  3H73 A;  4QN3 A;  4MC7 A;  2QWD A;  2XZI A;  2VK7 A;  5B2C A;  4DGR A;  2BER A;  1V2I A;  4X4A A;  4KS4 A;  2QWJ A;  2VW1 A;  4FJ6 A;  4GDJ A;  1B9S A;  4XMA A;  2W38 A;  4FPF A;  4BBW A;  2F25 A;  4XJR A;  2B8H A;  1W0O A;  2BAT A;  4H52 A;  4M4V A;  4FPH A;  2F10 A;  4XHX A;  4YZ2 A;  1N1T A;  4XJW A;  4KS3 A;  1S0I A;  2HT5 A;  2YA8 A;  4YW2 A;  4XJ9 A;  1NMA N;  1NNB A;  1INY A;  4NN9 A;  4MWY A;  1NSB A;  3D12 A;  3JU4 A;  2HTQ A;  4FOY A;  1IVC A;  4YZ5 A;  1W0P A;  2VW0 A;  3W09 A;  1V0E A;  2AGS A;  2HTV A;  4FQ4 A;  4MJV A;  1MS8 A;  2HTU A;  2VSM A;  4B7R A;  4MWR A;  1USR A;  1EUS A;  4XIK A;  4FPO B;  1N1V A;  4MJU A;  1E8U A;  2XZJ A;  1F8C A;  1NCD N;  4YW5 A;  3K37 A;  1L7H A;  2FHR A;  2W20 A;  3PJQ A;  1A4Q A;  4FOV A;  1BJI A;  4KS1 A;  2QWH A;  1MZ6 A;  3K39 A;  4GZT A;  4HZV A;  2XCY A;  1F8E A;  4XJ8 A;  1E8T A;  1IVF A;  1W21 A;  3CL2 A;  3K3A A;  2A75 A;  4QN4 A;  2AEQ A;  1VCU A;  4FPG A;  1NCC N;  4GZW A;  2AH2 A;  4NCS A;  4K1H A;  4MWV A;  3TIC A;  4CPM A;  3SAL A;  3CL0 A;  2YA4 A;  4MWX A;  5F9T A;  2X9M A;  1INV A;  1Z4Z A;  4UF7 A;  4YZ1 A;  4CPO A;  2F0Z A;  2HT8 A;  2RKC A;  2QWE A;  4XOG A;  4WA3 A;  4GEZ A;  3TI3 A;  3T1E A;  1F8B A;  1NSC A;  3NN9 A;  4WA4 A;  1Z4X A;  2QWG A;  1EUT A;  3GVJ A;  4GZS A;  1Z4V A;  1INF A;  1DIM A;  2SIM A;  3INB A;  4KS5 A;  4X49 A;  3D11 A;  4J9T A;  4B7Q A;  4QN5 A;  1W1X A;  1IVD A;  4XHB A;  2F27 A;  2W5O A;  5JYY A;  2YDT A;  1EUR A;  1SLI A;  4X47 A;  2BZD A;  1WCQ A;  2VSK A;  1IVE A;  2VK5 A;  3TI4 A;  1MS5 A;  4K1I A;  4MWJ A;  4MZA A;  3O9K A;  4QN6 A;  1L7G A;  1N1Y A;  1XOE A;  1V3C A;  1IVB A;  1NSD A;  4FPL A;  3CYE A;  6NN9 A;  4GB1 A;  3B69 A;  1W8O A;  2YDP A;  5M1Z A;  2QWB A;  2YA5 A;  4GZO A;  4M4N A;  1SNT A;  4FP2 A;  4XMI A;  1INW A;  2F11 A;  1NNA A;  1VCJ A;  2C4L A;  3H6J A;  2VVZ A;  1KIT A;  4HZW A;  2F24 A;  4B7J A;  4FVK A;  5HUG A;  4XJU A;  4HZY A;  3NSS A;  3OPZ A;  3A71 A;  2CML A;  4XIO A;  1W8N A;  5HUM A;  1MS0 A;  4YW1 A;  1MS1 A;  1V0Z A;  3TI8 A;  4GZX A;  4YW3 A;  1E8V A;  5HUN A;  4FPY A;  1W20 A;  5NN9 A;  2QWF A;  3H72 A;  2QWK A;  1MS9 A;  1V3B A;  1MWE A;  4XJA A;  4XJZ A;  4QNP A;  2XZK A;  4YW4 A;  2SIL A;  2YA6 A;  3CKZ A;  1SLL A;  4WA5 A;  2JKB A;  2C4A A;  4FP3 A;  1ING A;  2AEP A;  1B9T A;  3H71 A;  1N1S A;  1WCS A;  4XJQ A;  4JF7 A;  1MZ5 A;  1Z4Y A;  1EUU A;  4HZZ A;  2F26 A;  1NCB N;  1MR5 A;  4FPJ A;  3K36 A;  4H53 A;  2F13 A;  1V3E A;  3TI6 A;  1V0F A;  3ALX A;  2HTW A;  4GZQ A;  4CPZ A;  4NC5 A;  1A4G A; 
#chains in the Genus database with same CATH topology
 4XYX A;  4HW6 A;  4MX0 A;  4CPN A;  4K1J A;  4XIL A;  3SLI A;  3O4P A;  1INH A;  1NNC A;  4AGT A;  2ZB6 A;  4FZH A;  3ADE A;  1F8D A;  1INX A;  1N6D A;  4MWU A;  1MS4 A;  4CPL A;  2W8B B;  2ZB5 A;  2W8B A;  4X6K A;  4FOW A;  3HRP A;  4GDI A;  2HTR A;  4B7N A;  3GVK A;  1SO7 A;  1DIL A;  4Q6K A;  4YZ4 A;  2YA7 A;  3TC9 A;  4UOU A;  7NN9 A;  2GHS A;  5H47 A;  2IAT A;  3P5B L;  4FPK A;  1NPE A;  1S0J A;  1PJX A;  4MWW A;  2QWA A;  1CRU A;  4D8S A;  2F28 A;  2VK6 A;  2VWD A;  4IFL X;  3SAN A;  1Z50 A;  2FPB A;  3K38 A;  4AH4 A;  4MWQ A;  3A72 A;  2IVZ A;  4B7M A;  4QN7 A;  2VW2 A;  5GX4 A;  1C9U A;  4XE9 A;  3U0S A;  2QWC A;  1S1D A;  2BF6 A;  2H2N A;  2HU4 A;  1NN2 A;  4WEG A;  4I00 A;  4K1K A;  1XOG A;  4MZE A;  4SLI A;  4CPZ A;  3DR2 A;  1B9V A;  5HUK A;  1RWL A;  5GX5 A;  4GZP A;  1NMC A;  5FNT A;  3SRG A;  4FPE A;  4HIZ A;  4GJT A;  4ZLR A;  2F12 A;  3UC1 A;  3O9J A;  1IVG A;  4FPC A;  4M3M A;  4CPY A;  4M4U A;  3B7E A;  1NMB N;  3TIB A;  3GVL A;  3SOV A;  3ALW A;  2H2U A;  1X2J A;  4WEF A;  3TIA A;  2HU0 A;  1V3D A;  4R40 A;  1Z4W A;  4N1B A;  3V65 B;  3SIL A;  4O5S A;  4GN8 A;  3I1C A;  1USX A;  2HTY A;  3BYC A;  3WWA A;  4K3Y A;  3S2K A;  3G4E A;  5EO8 A;  1QLG A;  3NO0 A;  3S8Z A;  4CSD A;  4HZX A;  2QWI A;  1L7F A;  5HX0 A;  4YZ3 A;  4GNC A;  2W5N A;  1NCA N;  2HT7 A;  3KGG A;  4IN4 A;  5B2D A;  3TI5 A;  1MS3 A;  5D9B A;  1QBI A;  2SLI A;  4DG6 A;  2F29 A;  4FOQ A;  4KS2 A;  2IAO A;  3G4H A;  4MWL A;  2ZW9 A;  3BEQ A;  1A14 N;  3H73 A;  4O5T A;  4QN3 A;  2G8S A;  1ZGK A;  4MC7 A;  2QWD A;  2XZI A;  2VK7 A;  3S94 A;  5B2C A;  2OJH A;  3L6V A;  3FVZ A;  2BER A;  4DGR A;  1V2I A;  4X4A A;  4KS4 A;  2QWJ A;  1N7D A;  2VW1 A;  4FJ6 A;  4GDJ A;  4AGI A;  1B9S A;  4XMA A;  2W38 A;  4FPF A;  3AMR A;  4BBW A;  2F25 A;  4XJR A;  2B8H A;  2XN4 A;  1W0O A;  2BAT A;  4H52 A;  4M4V A;  3FW0 A;  4FPH A;  2F10 A;  4XHX A;  4YZ2 A;  1N1T A;  4XJW A;  4KS3 A;  1S0I A;  2HT5 A;  2YA8 A;  4CH9 A;  4YW2 A;  1E1A A;  4XJ9 A;  1NMA N;  5GX3 A;  1NNB A;  1INY A;  4NN9 A;  4MWY A;  1NSB A;  3D12 A;  3JU4 A;  1CQ1 A;  2HTQ A;  5EO7 A;  5FZN A;  4FOY A;  5FNR A;  3ZGC A;  1IVC A;  4YZ5 A;  1W0P A;  2VW0 A;  3W09 A;  5D9D A;  4IQK A;  1V0E A;  2AGS A;  2HTV A;  4FQ4 A;  4MJV A;  3V64 C;  3AMS A;  1MS8 A;  2HTU A;  4D4U A;  5GX1 A;  2VSM A;  4B7R A;  3SOB B;  4MWR A;  1USR A;  3S8V A;  1EUS A;  4XIK A;  1OFZ A;  3KYA A;  2DG1 A;  4FPO B;  1N1V A;  4MJU A;  4ZGC A;  5D9C A;  1E8U A;  2XZJ A;  3WDZ A;  2GVW A;  1F8C A;  1NCD N;  1U6D X;  3K37 A;  1L7H A;  4YW5 A;  1C5K A;  2FHR A;  2W20 A;  3PJQ A;  4GN9 A;  1A4Q A;  4FOV A;  1BJI A;  2Z32 A;  2QWH A;  4KS1 A;  1MZ6 A;  3K39 A;  4GZT A;  4HZV A;  2XCY A;  1F8E A;  1N6F A;  4XJ8 A;  4YY8 A;  1E8T A;  1IVF A;  2DG0 A;  1W21 A;  3CL2 A;  3K3A A;  2A75 A;  4QN4 A;  2AEQ A;  3VNG A;  1VCU A;  4FPG A;  1CRZ A;  3II7 A;  2P4O A;  1NCC N;  4GZW A;  4ASC A;  2FLU X;  2AH2 A;  2IAU A;  4HHQ A;  4NCS A;  5GTQ A;  4K1H A;  4MWV A;  3TIC A;  4CPM A;  3SAL A;  4IFJ A;  4CHB A;  3CL0 A;  3HLI A;  2HQS A;  4L7C A;  2YA4 A;  2VPJ A;  4MWX A;  5F9T A;  2X9M A;  1INV A;  1Z4Z A;  4ZY3 A;  4UF7 A;  4YZ1 A;  5GX2 A;  4CPO A;  2F0Z A;  2HT8 A;  2RKC A;  2QWE A;  5FZJ A;  4XOG A;  2FP9 A;  2GVV A;  4WA3 A;  4GEZ A;  1WP5 A;  4G3N A;  3TI3 A;  3T1E A;  3DAS A;  1F8B A;  1NSC A;  3NN9 A;  1H6L A;  4WA4 A;  1Z4X A;  5FNU A;  2QWG A;  1V04 A;  3VNH A;  1EUT A;  2ISM A;  3GVJ A;  3HLH A;  4GZS A;  1Z4V A;  1INF A;  1DIM A;  2SIM A;  3INB A;  5CGJ A;  4KS5 A;  4X49 A;  2VAQ A;  3D11 A;  4J9T A;  4B7Q A;  4QN5 A;  1W1X A;  1IVD A;  4XHB A;  4Q1U A;  2F27 A;  2W5O A;  5JYY A;  2YDT A;  3IAX A;  4IMB A;  1EUR A;  1SLI A;  2IAV A;  4AHA A;  4X47 A;  4GNA A;  3WW9 A;  2BZD A;  1WCQ A;  5EX7 A;  4L7B A;  2VSK A;  1IVE A;  2VK5 A;  3TI4 A;  1MS5 A;  4K1I A;  4MWJ A;  4MZA A;  3O9K A;  4QN6 A;  1L7G A;  1N1Y A;  1XOE A;  2DSO A;  1V3C A;  1IVB A;  1NSD A;  4FPL A;  1K32 A;  1SUU A;  3SRE A;  3CYE A;  6NN9 A;  4GB1 A;  4IYG A;  3B69 A;  1W8O A;  2YDP A;  5M1Z A;  2FP8 A;  2IAS A;  2QWB A;  2YA5 A;  2FPC A;  4GZO A;  4M4N A;  1SNT A;  4FP2 A;  4XMI A;  1INW A;  3WN7 A;  2F11 A;  1NNA A;  1VCJ A;  3SOQ A;  4IFN X;  2C4L A;  3H6J A;  2VVZ A;  4A0P A;  1KIT A;  3Q6T A;  4HZW A;  1X2R A;  2F24 A;  4B7J A;  4FVK A;  2IAQ A;  5HUG A;  4XJU A;  3ZGD A;  2GVU A;  4HZY A;  1IJQ A;  3NSS A;  3OPZ A;  3A71 A;  2CML A;  2IAX A;  4XIO A;  2GVX A;  1W8N A;  5FNS A;  5HUM A;  1MS0 A;  4YW1 A;  4GNB A;  2ZZK A;  1N6E A;  1S18 A;  1MS1 A;  4D52 B;  1V0Z A;  4D52 A;  3TI8 A;  4GZX A;  4YW3 A;  3E5Z A;  4JML A;  1E8V A;  5HUN A;  4GN7 A;  4FPY A;  2IAP A;  1W20 A;  2QE8 A;  5NN9 A;  2QWF A;  1Q7F A;  3H72 A;  2QWK A;  3A9G A;  1MS9 A;  1ZI0 A;  3LI4 A;  1V3B A;  5FNQ A;  1MWE A;  2WOZ A;  4XJA A;  4PWZ A;  3LI3 A;  4XJZ A;  1RWI A;  4QNP A;  2XZK A;  4YW4 A;  2SIL A;  2YA6 A;  3CKZ A;  1SLL A;  2IAR A;  4WA5 A;  1POO A;  2JKB A;  2C4A A;  4L7D A;  4FP3 A;  3Q6P A;  1ING A;  2AEP A;  4D52 C;  1B9T A;  3H71 A;  1N1S A;  1WCS A;  4XJQ A;  4JF7 A;  1MZ5 A;  5F72 C;  1Z4Y A;  1EUU A;  2IAW A;  3Q6K A;  4HZZ A;  2F26 A;  2DYH A;  3V1S A;  2POO A;  4XMB A;  1NCB N;  1MR5 A;  4FPJ A;  3K36 A;  4H53 A;  1CVM A;  5FWW A;  2F13 A;  1V3E A;  3TI6 A;  1V0F A;  3A9H A;  2V91 A;  3ALX A;  2HTW A;  3LI5 A;  1IUC A;  4GZQ A;  4C1Y B;  4C1Y A;  2ZWA A;  4HHO A;  1IUB A;  4NC5 A;  1A4G A; 
#chains in the Genus database with same CATH homology
 4XYX A;  4MX0 A;  4CPN A;  4K1J A;  4XIL A;  3SLI A;  1INH A;  1NNC A;  2ZB6 A;  4FZH A;  1F8D A;  1INX A;  4MWU A;  1MS4 A;  4CPL A;  2ZB5 A;  4X6K A;  4FOW A;  4GDI A;  2HTR A;  4B7N A;  3GVK A;  1SO7 A;  1DIL A;  4Q6K A;  4YZ4 A;  2YA7 A;  7NN9 A;  4FPK A;  1S0J A;  4MWW A;  2QWA A;  4D8S A;  2F28 A;  2VK6 A;  2VWD A;  3SAN A;  1Z50 A;  3K38 A;  4MWQ A;  3A72 A;  4B7M A;  4QN7 A;  2VW2 A;  4XE9 A;  2QWC A;  1S1D A;  2BF6 A;  2H2N A;  2HU4 A;  1NN2 A;  4WEG A;  4I00 A;  4K1K A;  1XOG A;  4MZE A;  4SLI A;  1B9V A;  5HUK A;  4GZP A;  1NMC A;  4FPE A;  4HIZ A;  4GJT A;  2F12 A;  3O9J A;  1IVG A;  4FPC A;  4M3M A;  4CPY A;  4M4U A;  3B7E A;  1NMB N;  3TIB A;  3GVL A;  3ALW A;  2H2U A;  4WEF A;  3TIA A;  2HU0 A;  1V3D A;  1Z4W A;  3SIL A;  1USX A;  2HTY A;  4K3Y A;  4HZX A;  2QWI A;  1L7F A;  5HX0 A;  4YZ3 A;  2W5N A;  1NCA N;  2HT7 A;  5B2D A;  3TI5 A;  1MS3 A;  2SLI A;  2F29 A;  4FOQ A;  4KS2 A;  4MWL A;  3BEQ A;  1A14 N;  3H73 A;  4QN3 A;  4MC7 A;  2QWD A;  2XZI A;  2VK7 A;  5B2C A;  4DGR A;  2BER A;  1V2I A;  4X4A A;  4KS4 A;  2QWJ A;  2VW1 A;  4FJ6 A;  4GDJ A;  1B9S A;  4XMA A;  2W38 A;  4FPF A;  4BBW A;  2F25 A;  4XJR A;  2B8H A;  1W0O A;  2BAT A;  4H52 A;  4M4V A;  4FPH A;  2F10 A;  4XHX A;  4YZ2 A;  1N1T A;  4XJW A;  4KS3 A;  1S0I A;  2HT5 A;  2YA8 A;  4YW2 A;  4XJ9 A;  1NMA N;  1NNB A;  1INY A;  4NN9 A;  4MWY A;  1NSB A;  3D12 A;  3JU4 A;  2HTQ A;  4FOY A;  1IVC A;  4YZ5 A;  1W0P A;  2VW0 A;  3W09 A;  1V0E A;  2AGS A;  2HTV A;  4FQ4 A;  4MJV A;  1MS8 A;  2HTU A;  2VSM A;  4B7R A;  4MWR A;  1USR A;  1EUS A;  4XIK A;  4FPO B;  1N1V A;  4MJU A;  1E8U A;  2XZJ A;  1F8C A;  1NCD N;  4YW5 A;  3K37 A;  1L7H A;  2FHR A;  2W20 A;  3PJQ A;  1A4Q A;  4FOV A;  1BJI A;  4KS1 A;  2QWH A;  1MZ6 A;  3K39 A;  4GZT A;  4HZV A;  2XCY A;  1F8E A;  4XJ8 A;  1E8T A;  1IVF A;  1W21 A;  3CL2 A;  3K3A A;  2A75 A;  4QN4 A;  2AEQ A;  1VCU A;  4FPG A;  1NCC N;  4GZW A;  2AH2 A;  4NCS A;  4K1H A;  4MWV A;  3TIC A;  4CPM A;  3SAL A;  3CL0 A;  2YA4 A;  4MWX A;  5F9T A;  2X9M A;  1INV A;  1Z4Z A;  4UF7 A;  4YZ1 A;  4CPO A;  2F0Z A;  2HT8 A;  2RKC A;  2QWE A;  4XOG A;  4WA3 A;  4GEZ A;  3TI3 A;  3T1E A;  1F8B A;  1NSC A;  3NN9 A;  4WA4 A;  1Z4X A;  2QWG A;  1EUT A;  3GVJ A;  4GZS A;  1Z4V A;  1INF A;  1DIM A;  2SIM A;  3INB A;  4KS5 A;  4X49 A;  3D11 A;  4J9T A;  4B7Q A;  4QN5 A;  1W1X A;  1IVD A;  4XHB A;  2F27 A;  2W5O A;  5JYY A;  2YDT A;  1EUR A;  1SLI A;  4X47 A;  2BZD A;  1WCQ A;  2VSK A;  1IVE A;  2VK5 A;  3TI4 A;  1MS5 A;  4K1I A;  4MWJ A;  4MZA A;  3O9K A;  4QN6 A;  1L7G A;  1N1Y A;  1XOE A;  1V3C A;  1IVB A;  1NSD A;  4FPL A;  3CYE A;  6NN9 A;  4GB1 A;  3B69 A;  1W8O A;  2YDP A;  5M1Z A;  2QWB A;  2YA5 A;  4GZO A;  4M4N A;  1SNT A;  4FP2 A;  4XMI A;  1INW A;  2F11 A;  1NNA A;  1VCJ A;  2C4L A;  3H6J A;  2VVZ A;  1KIT A;  4HZW A;  2F24 A;  4B7J A;  4FVK A;  5HUG A;  4XJU A;  4HZY A;  3NSS A;  3OPZ A;  3A71 A;  2CML A;  4XIO A;  1W8N A;  5HUM A;  1MS0 A;  4YW1 A;  1S18 A;  1MS1 A;  1V0Z A;  3TI8 A;  4GZX A;  4YW3 A;  1E8V A;  5HUN A;  4FPY A;  1W20 A;  5NN9 A;  2QWF A;  3H72 A;  2QWK A;  1MS9 A;  1V3B A;  1MWE A;  4XJA A;  4XJZ A;  4QNP A;  2XZK A;  4YW4 A;  2SIL A;  2YA6 A;  3CKZ A;  1SLL A;  4WA5 A;  2JKB A;  2C4A A;  4FP3 A;  1ING A;  2AEP A;  1B9T A;  3H71 A;  1N1S A;  1WCS A;  4XJQ A;  4JF7 A;  1MZ5 A;  1Z4Y A;  1EUU A;  4HZZ A;  2F26 A;  1NCB N;  1MR5 A;  4FPJ A;  3K36 A;  4H53 A;  2F13 A;  1V3E A;  3TI6 A;  1V0F A;  3ALX A;  2HTW A;  4GZQ A;  4CPZ A;  4NC5 A;  1A4G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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