2Z32A

Crystal structure of keap1 complexed with prothymosin alpha
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
290
structure length
290
Chain Sequence
VGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEPC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural analysis of the complex of Keap1 with a prothymosin alpha peptide
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords Kelch-like ECH-associated protein 1
total genus 61
structure length 290
sequence length 290
ec nomenclature
pdb deposition date 2007-05-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 2z32A00
3VNHA 5F72C 5FNUA 4ASCA 5CGJA 3ZGCA 5FNTA 4IN4A 4IFNX 3ZGDA 2ZZKA 1X2RA 1X2JA 5FNQA 4L7DA 4IQKA 4ZY3A 2ZWAA 3WN7A 5FZJA 3ADEA 4CHBA 2WOZA 1ZGKA 2VPJA 4L7BA 2XN4A 4IFLX 1U6DX 2Z32A 5FNSA 4L7CA 3VNGA 3WDZA 2ZW9A 4CH9A 4N1BA 4YY8A 5FZNA 4ZGCA 2DYHA 4XMBA 4IFJA 2FLUX 5FNRA 3II7A
chains in the Genus database with same CATH superfamily
2FPCA 3K38A 3SANA 5HUNA 2HT8A 4B7RA 1SO7A 1V0EA 4GNCA 4XJAA 4MWVA 2IAXA 4M4UA 1W8OA 5FWWA 1CRZA 2GVWA 1Z4VA 1Q7FA 3Q6PA 4GN7A 1F8BA 1CQ1A 3ALWA 4IFLX 2XZIA 2Z32A 1NCAN 2DG0A 3I1CA 2QWEA 3Q6TA 4GNAA 2SLIA 1MS1A 1V3BA 2F24A 2F10A 2VVZA 4K1HA 2HQSA 1Z4ZA 1INGA 4NC5A 3BEQA 1S0IA 5FNRA 2F12A 2IAPA 1IVEA 3NN9A 4IN4A 2H2UA 2VWDA 2B8HA 2OJHA 4FPYA 3FVZA 1USRA 4HHOA 1DILA 4HZVA 4X6KA 4XJ8A 4XHXA 2W8BA 1ZGKA 1Z4XA 3S8ZA 3V65B 1MS4A 2FP9A 4GZQA 2X9MA 1SLIA 5D9BA 4YW5A 5HX0A 4HHQA 2HTVA 3A72A 2QWGA 1VCUA 4MWWA 4MWLA 2BF6A 3H71A 2HTUA 1IVCA 3TI5A 4XOGA 3K36A 2HTYA 4HZZA 4MJUA 4FPEA 4GJTA 4CPOA 3TI4A 4YZ1A 1V3DA 1W8NA 1A4QA 4XIOA 4MJVA 3BYCA 4D8SA 3T1EA 4MWUA 2QWJA 3KGGA 2DSOA 5EX7A 3SRGA 4ZGCA 3TIBA 1NN2A 4AGTA 4AH4A 4GDIA 4QN4A 1PJXA 4MWXA 4YZ3A 1L7FA 4QN7A 4GZWA 2VAQA 5F9TA 2QWHA 4KS3A 3WW9A 3CL0A 1NNCA 4L7DA 4WEFA 4FPJA 5M1ZA 1DIMA 3TI8A 3G4HA 2IAUA 4GB1A 4G3NA 3SLIA 2QWCA 1INYA 3D12A 1C5KA 4K1IA 2GVUA 3GVLA 4CPMA 1N6FA 1NPEA 4D52C 2SILA 4Q1UA 1E8UA 5FZNA 1IJQA 2ZB6A 4HZXA 1MZ5A 4AHAA 3II7A 1NCDN 1W0PA 4Q6KA 2W5OA 3CYEA 1NNBA 4R40A 2GVVA 2VK6A 5GX2A 2QWDA 4XILA 4XMIA 2BERA 4FPKA 2JKBA 5GX4A 1W0OA 1EUSA 4XYXA 4PWZA 3S8VA 2AH2A 4CPNA 4D52A 4KS4A 3LI3A 3U0SA 3FW0A 1E8TA 2QWAA 1OFZA 2F27A 4YW1A 1IUCA 4FOQA 5CGJA 4MZEA 3K39A 5B2CA 3KYAA 4ZY3A 4FPHA 3TIAA 3ADEA 4KS1A 4GZPA 5EO8A 2F26A 4IMBA 4XHBA 5H47A 3SALA 3G4EA 4HIZA 4KS2A 4YZ5A 1MS5A 2HTQA 2FHRA 2ZW9A 1NSCA 4K1KA 4M4NA 4GZXA 4CH9A 2VW2A 1IVFA 2HTRA 2QE8A 1NSBA 2ZB5A 1B9TA 4A0PA 1XOGA 3B7EA 4B7NA 2C4LA 2F25A 4CPLA 4FPLA 1X2RA 3D11A 5D9DA 4M3MA 2C4AA 4UOUA 2YA5A 5HUMA 3SOQA 4GZSA 1INFA 3AMRA 3SOVA 2BZDA 3TC9A 4AGIA 2IATA 2YDTA 4YZ2A 3WDZA 1NCBN 2QWIA 4XJQA 1Z50A 4YY8A 2F29A 4C1YB 4JMLA 4FVKA 1IVGA 4DG6A 4ASCA 2VSMA 3CKZA 4C1YA 2HU0A 3A9HA 1S1DA 3V64C 1INHA 1Z4YA 4FP2A 2IAQA 2F28A 1Z4WA 2IASA 2F0ZA 1V3EA 2VSKA 4FQ4A 3A71A 3UC1A 1W1XA 4K1JA 1INXA 4D4UA 3V1SA 4FPCA 4WA5A 3O9JA 2FLUX 1EUUA 4FPGA 4YW4A 1NMBN 4NN9A 4XJWA 3CL2A 3ALXA 4HZYA 3O4PA 4B7MA 4QN6A 4MC7A 2IAVA 2VK5A 3HLHA 1QLGA 2BATA 2CMLA 3Q6KA 1INWA 4MWYA 4FPOB 2YDPA 4QNPA 1QBIA 1WCSA 1E8VA 2IAOA 2YA6A 2IARA 2YA4A 3DASA 4X4AA 2ZWAA 5EO7A 4X47A 1XOEA 2VPJA 2AEPA 1IUBA 1V2IA 1CVMA 2F11A 1U6DX 3WWAA 1B9VA 4J9TA 4L7CA 1MZ6A 1RWIA 3A9GA 3NO0A 1W20A 2G8SA 3W09A 2QWKA 2DG1A 1SUUA 4HW6A 2GVXA 4XIKA 1L7HA 3ZGCA 4QN5A 4XJRA 3K3AA 2A75A 1X2JA 2FP8A 4FPFA 4IQKA 1A4GA 2V91A 1IVDA 3DR2A 4GZOA 3GVKA 1S0JA 1A14N 3LI5A 4CPZA 4JF7A 4GDJA 4SLIA 4NCSA 3HLIA 4O5SA 2FPBA 4WEGA 1EUTA 1K32A 4FJ6A 1MS3A 1E1AA 6NN9A 1N7DA 3ZGDA 3INBA 1MS0A 1V0ZA 3SILA 4X49A 5NN9A 4L7BA 3GVJA 3TI3A 5D9CA 1KITA 2IAWA 4FOWA 2AEQA 5HUGA 5GX5A 1IVBA 1S18A 1EURA 3S2KA 1V3CA 1VCJA 2QWBA 4XJUA 7NN9A 3H72A 5FNUA 2W20A 2W8BB 4FP3A 1N1TA 4IFNX 5GX1A 1NMAN 1SLLA 4M4VA 3P5BL 3WN7A 1H6LA 2HTWA 3K37A 3IAXA 4CHBA 2XZJA 2VW0A 1N1YA 3PJQA 2ISMA 1NMCA 4XJZA 1ZI0A 3O9KA 4IYGA 4XMAA 5FNSA 3JU4A 3NSSA 3VNGA 4DGRA 4WA3A 2W5NA 1NNAA 2QWFA 2HU4A 2HT5A 3TI6A 5GX3A 4FOVA 4B7QA 1F8CA 1NSDA 5GTQA 1L7GA 5FNTA 2POOA 4YW2A 4FZHA 3H73A 2P4OA 4XE9A 5FZJA 3SOBB 2AGSA 4YW3A 2WOZA 1C9UA 1MS9A 2GHSA 3S94A 2IVZA 3L6VA 1N1SA 1V04A 4QN3A 2H2NA 4I00A 4MWJA 4H53A 1MR5A 4CPYA 4XMBA 3B69A 1N6DA 4MWRA 1WP5A 4K3YA 3SREA 4GN9A 2RKCA 1B9SA 2VK7A 4GNBA 4HZWA 4CSDA 5JYYA 3H6JA 1V0FA 2SIMA 2F13A 4GZTA 4O5TA 2VW1A 1N6EA 4FOYA 4KS5A 3E5ZA 4XJ9A 1F8EA 1INVA 4UF7A 2YA8A 3TICA 2YA7A 1MS8A 4H52A 4BBWA 1N1VA 2HT7A 4MX0A 4IFJA 1SNTA 3VNHA 1CRUA 5F72C 1RWLA 5B2DA 1BJIA 1W21A 2ZZKA 5FNQA 4ZLRA 4WA4A 2XCYA 3OPZA 1F8DA 3AMSA 4MWQA 2XN4A 4GN8A 4D52B 1USXA 4GEZA 4YZ4A 2XZKA 4B7JA 1WCQA 4N1BA 1POOA 4MZAA 1MWEA 3LI4A 5HUKA 2DYHA 2W38A 3HRPA 1NCCN
chains in the Genus database with same CATH topology
3VNHA 5F72C 5FNUA 4ASCA 5CGJA 3ZGCA 5FNTA 4IN4A 4IFNX 3ZGDA 2ZZKA 1X2RA 1X2JA 5FNQA 4L7DA 4IQKA 4ZY3A 2ZWAA 3WN7A 5FZJA 3ADEA 4CHBA 2WOZA 1ZGKA 2VPJA 4L7BA 2XN4A 4IFLX 1U6DX 2Z32A 5FNSA 4L7CA 3VNGA 3WDZA 2ZW9A 4CH9A 4N1BA 4YY8A 5FZNA 4ZGCA 2DYHA 4XMBA 4IFJA 2FLUX 5FNRA 3II7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3VNH A;  5F72 C;  5FNU A;  4ASC A;  5CGJ A;  3ZGC A;  5FNT A;  4IN4 A;  4IFN X;  3ZGD A;  2ZZK A;  1X2R A;  1X2J A;  5FNQ A;  4L7D A;  4IQK A;  4ZY3 A;  2ZWA A;  3WN7 A;  5FZJ A;  3ADE A;  4CHB A;  2WOZ A;  1ZGK A;  2VPJ A;  4L7B A;  2XN4 A;  4IFL X;  1U6D X;  2Z32 A;  5FNS A;  4L7C A;  3VNG A;  3WDZ A;  2ZW9 A;  4CH9 A;  4N1B A;  4YY8 A;  5FZN A;  4ZGC A;  2DYH A;  4XMB A;  4IFJ A;  2FLU X;  5FNR A;  3II7 A; 
#chains in the Genus database with same CATH topology
 2FPC A;  3K38 A;  3SAN A;  5HUN A;  2HT8 A;  4B7R A;  1SO7 A;  1V0E A;  4GNC A;  4XJA A;  4MWV A;  2IAX A;  4M4U A;  1W8O A;  5FWW A;  1CRZ A;  2GVW A;  1Z4V A;  1Q7F A;  3Q6P A;  4GN7 A;  1F8B A;  1CQ1 A;  3ALW A;  4IFL X;  2XZI A;  2Z32 A;  1NCA N;  2DG0 A;  3I1C A;  2QWE A;  3Q6T A;  4GNA A;  2SLI A;  1MS1 A;  1V3B A;  2F24 A;  2F10 A;  2VVZ A;  4K1H A;  2HQS A;  1Z4Z A;  1ING A;  4NC5 A;  3BEQ A;  1S0I A;  5FNR A;  2F12 A;  2IAP A;  1IVE A;  3NN9 A;  4IN4 A;  2H2U A;  2VWD A;  2B8H A;  2OJH A;  4FPY A;  3FVZ A;  1USR A;  4HHO A;  1DIL A;  4HZV A;  4X6K A;  4XJ8 A;  4XHX A;  2W8B A;  1ZGK A;  1Z4X A;  3S8Z A;  3V65 B;  1MS4 A;  2FP9 A;  4GZQ A;  2X9M A;  1SLI A;  5D9B A;  4YW5 A;  5HX0 A;  4HHQ A;  2HTV A;  3A72 A;  2QWG A;  1VCU A;  4MWW A;  4MWL A;  2BF6 A;  3H71 A;  2HTU A;  1IVC A;  3TI5 A;  4XOG A;  3K36 A;  2HTY A;  4HZZ A;  4MJU A;  4FPE A;  4GJT A;  4CPO A;  3TI4 A;  4YZ1 A;  1V3D A;  1W8N A;  1A4Q A;  4XIO A;  4MJV A;  3BYC A;  4D8S A;  3T1E A;  4MWU A;  2QWJ A;  3KGG A;  2DSO A;  5EX7 A;  3SRG A;  4ZGC A;  3TIB A;  1NN2 A;  4AGT A;  4AH4 A;  4GDI A;  4QN4 A;  1PJX A;  4MWX A;  4YZ3 A;  1L7F A;  4QN7 A;  4GZW A;  2VAQ A;  5F9T A;  2QWH A;  4KS3 A;  3WW9 A;  3CL0 A;  1NNC A;  4L7D A;  4WEF A;  4FPJ A;  5M1Z A;  1DIM A;  3TI8 A;  3G4H A;  2IAU A;  4GB1 A;  4G3N A;  3SLI A;  2QWC A;  1INY A;  3D12 A;  1C5K A;  4K1I A;  2GVU A;  3GVL A;  4CPM A;  1N6F A;  1NPE A;  4D52 C;  2SIL A;  4Q1U A;  1E8U A;  5FZN A;  1IJQ A;  2ZB6 A;  4HZX A;  1MZ5 A;  4AHA A;  3II7 A;  1NCD N;  1W0P A;  4Q6K A;  2W5O A;  3CYE A;  1NNB A;  4R40 A;  2GVV A;  2VK6 A;  5GX2 A;  2QWD A;  4XIL A;  4XMI A;  2BER A;  4FPK A;  2JKB A;  5GX4 A;  1W0O A;  1EUS A;  4XYX A;  4PWZ A;  3S8V A;  2AH2 A;  4CPN A;  4D52 A;  4KS4 A;  3LI3 A;  3U0S A;  3FW0 A;  1E8T A;  2QWA A;  1OFZ A;  2F27 A;  4YW1 A;  1IUC A;  4FOQ A;  5CGJ A;  4MZE A;  3K39 A;  5B2C A;  3KYA A;  4ZY3 A;  4FPH A;  3TIA A;  3ADE A;  4KS1 A;  4GZP A;  5EO8 A;  2F26 A;  4IMB A;  4XHB A;  5H47 A;  3SAL A;  3G4E A;  4HIZ A;  4KS2 A;  4YZ5 A;  1MS5 A;  2HTQ A;  2FHR A;  2ZW9 A;  1NSC A;  4K1K A;  4M4N A;  4GZX A;  4CH9 A;  2VW2 A;  1IVF A;  2HTR A;  2QE8 A;  1NSB A;  2ZB5 A;  1B9T A;  4A0P A;  1XOG A;  3B7E A;  4B7N A;  2C4L A;  2F25 A;  4CPL A;  4FPL A;  1X2R A;  3D11 A;  5D9D A;  4M3M A;  2C4A A;  4UOU A;  2YA5 A;  5HUM A;  3SOQ A;  4GZS A;  1INF A;  3AMR A;  3SOV A;  2BZD A;  3TC9 A;  4AGI A;  2IAT A;  2YDT A;  4YZ2 A;  3WDZ A;  1NCB N;  2QWI A;  4XJQ A;  1Z50 A;  4YY8 A;  2F29 A;  4C1Y B;  4JML A;  4FVK A;  1IVG A;  4DG6 A;  4ASC A;  2VSM A;  3CKZ A;  4C1Y A;  2HU0 A;  3A9H A;  1S1D A;  3V64 C;  1INH A;  1Z4Y A;  4FP2 A;  2IAQ A;  2F28 A;  1Z4W A;  2IAS A;  2F0Z A;  1V3E A;  2VSK A;  4FQ4 A;  3A71 A;  3UC1 A;  1W1X A;  4K1J A;  1INX A;  4D4U A;  3V1S A;  4FPC A;  4WA5 A;  3O9J A;  2FLU X;  1EUU A;  4FPG A;  4YW4 A;  1NMB N;  4NN9 A;  4XJW A;  3CL2 A;  3ALX A;  4HZY A;  3O4P A;  4B7M A;  4QN6 A;  4MC7 A;  2IAV A;  2VK5 A;  3HLH A;  1QLG A;  2BAT A;  2CML A;  3Q6K A;  1INW A;  4MWY A;  4FPO B;  2YDP A;  4QNP A;  1QBI A;  1WCS A;  1E8V A;  2IAO A;  2YA6 A;  2IAR A;  2YA4 A;  3DAS A;  4X4A A;  2ZWA A;  5EO7 A;  4X47 A;  1XOE A;  2VPJ A;  2AEP A;  1IUB A;  1V2I A;  1CVM A;  2F11 A;  1U6D X;  3WWA A;  1B9V A;  4J9T A;  4L7C A;  1MZ6 A;  1RWI A;  3A9G A;  3NO0 A;  1W20 A;  2G8S A;  3W09 A;  2QWK A;  2DG1 A;  1SUU A;  4HW6 A;  2GVX A;  4XIK A;  1L7H A;  3ZGC A;  4QN5 A;  4XJR A;  3K3A A;  2A75 A;  1X2J A;  2FP8 A;  4FPF A;  4IQK A;  1A4G A;  2V91 A;  1IVD A;  3DR2 A;  4GZO A;  3GVK A;  1S0J A;  1A14 N;  3LI5 A;  4CPZ A;  4JF7 A;  4GDJ A;  4SLI A;  4NCS A;  3HLI A;  4O5S A;  2FPB A;  4WEG A;  1EUT A;  1K32 A;  4FJ6 A;  1MS3 A;  1E1A A;  6NN9 A;  1N7D A;  3ZGD A;  3INB A;  1MS0 A;  1V0Z A;  3SIL A;  4X49 A;  5NN9 A;  4L7B A;  3GVJ A;  3TI3 A;  5D9C A;  1KIT A;  2IAW A;  4FOW A;  2AEQ A;  5HUG A;  5GX5 A;  1IVB A;  1S18 A;  1EUR A;  3S2K A;  1V3C A;  1VCJ A;  2QWB A;  4XJU A;  7NN9 A;  3H72 A;  5FNU A;  2W20 A;  2W8B B;  4FP3 A;  1N1T A;  4IFN X;  5GX1 A;  1NMA N;  1SLL A;  4M4V A;  3P5B L;  3WN7 A;  1H6L A;  2HTW A;  3K37 A;  3IAX A;  4CHB A;  2XZJ A;  2VW0 A;  1N1Y A;  3PJQ A;  2ISM A;  1NMC A;  4XJZ A;  1ZI0 A;  3O9K A;  4IYG A;  4XMA A;  5FNS A;  3JU4 A;  3NSS A;  3VNG A;  4DGR A;  4WA3 A;  2W5N A;  1NNA A;  2QWF A;  2HU4 A;  2HT5 A;  3TI6 A;  5GX3 A;  4FOV A;  4B7Q A;  1F8C A;  1NSD A;  5GTQ A;  1L7G A;  5FNT A;  2POO A;  4YW2 A;  4FZH A;  3H73 A;  2P4O A;  4XE9 A;  5FZJ A;  3SOB B;  2AGS A;  4YW3 A;  2WOZ A;  1C9U A;  1MS9 A;  2GHS A;  3S94 A;  2IVZ A;  3L6V A;  1N1S A;  1V04 A;  4QN3 A;  2H2N A;  4I00 A;  4MWJ A;  4H53 A;  1MR5 A;  4CPY A;  4XMB A;  3B69 A;  1N6D A;  4MWR A;  1WP5 A;  4K3Y A;  3SRE A;  4GN9 A;  2RKC A;  1B9S A;  2VK7 A;  4GNB A;  4HZW A;  4CSD A;  5JYY A;  3H6J A;  1V0F A;  2SIM A;  2F13 A;  4GZT A;  4O5T A;  2VW1 A;  1N6E A;  4FOY A;  4KS5 A;  3E5Z A;  4XJ9 A;  1F8E A;  1INV A;  4UF7 A;  2YA8 A;  3TIC A;  2YA7 A;  1MS8 A;  4H52 A;  4BBW A;  1N1V A;  2HT7 A;  4MX0 A;  4IFJ A;  1SNT A;  3VNH A;  1CRU A;  5F72 C;  1RWL A;  5B2D A;  1BJI A;  1W21 A;  2ZZK A;  5FNQ A;  4ZLR A;  4WA4 A;  2XCY A;  3OPZ A;  1F8D A;  3AMS A;  4MWQ A;  2XN4 A;  4GN8 A;  4D52 B;  1USX A;  4GEZ A;  4YZ4 A;  2XZK A;  4B7J A;  1WCQ A;  4N1B A;  1POO A;  4MZA A;  1MWE A;  3LI4 A;  5HUK A;  2DYH A;  2W38 A;  3HRP A;  1NCC N; 
#chains in the Genus database with same CATH homology
 3VNH A;  5F72 C;  5FNU A;  4ASC A;  5CGJ A;  3ZGC A;  5FNT A;  4IN4 A;  4IFN X;  3ZGD A;  2ZZK A;  1X2R A;  1X2J A;  5FNQ A;  4L7D A;  4IQK A;  4ZY3 A;  2ZWA A;  3WN7 A;  5FZJ A;  3ADE A;  4CHB A;  2WOZ A;  1ZGK A;  2VPJ A;  4L7B A;  2XN4 A;  4IFL X;  1U6D X;  2Z32 A;  5FNS A;  4L7C A;  3VNG A;  3WDZ A;  2ZW9 A;  4CH9 A;  4N1B A;  4YY8 A;  5FZN A;  4ZGC A;  2DYH A;  4XMB A;  4IFJ A;  2FLU X;  5FNR A;  3II7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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