3II7 | Genus

Total Genus 63

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	63
sequence length	288
structure length	288
Chain Sequence	KHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTC

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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Viewer cachePut cache://localLOAD_/file/5cff29d56bf5927ac5c90e66/pdb.gz

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Protein binding
source organism	Homo sapiens
publication title	Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases. pubmed doi rcsb
molecule keywords	Kelch-like protein 7
total genus	63
structure length	288
sequence length	288
ec nomenclature
pdb deposition date	2009-07-31

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01344	Kelch_1	Kelch motif

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.120.10.80	Mainly Beta	6 Propeller	Neuraminidase	Kelch-type beta propeller	3ii7A00

5FNQA 5FZJA 1U6DX 3ZGDA 1X2JA 4IFJA 2Z32A 2XN4A 4CHBA 3II7A 1ZGKA 2ZW9A 4IFLX 4L7BA 4YY8A 5FNTA 2DYHA 2WOZA 4IN4A 5FNRA 3ZGCA 4IQKA 4XMBA 5FNSA 3VNHA 4L7CA 3ADEA 4ASCA 4IFNX 5F72C 3WDZA 2ZZKA 4N1BA 5FZNA 5FNUA 2ZWAA 1X2RA 4ZY3A 2VPJA 2FLUX 3WN7A 4ZGCA 3VNGA 4CH9A 5CGJA 4L7DA
chains in the Genus database with same CATH superfamily

5GX5A 1WP5A 1WCQA 2QWBA 4B7MA 1N1VA 2FPBA 1IVFA 2F0ZA 4GNCA 1V2IA 4GNBA 1CQ1A 3S2KA 3BYCA 4IN4A 2QWJA 4UF7A 2F12A 4AGTA 3A9GA 2VK7A 4MWXA 1N6FA 3ADEA 3E5ZA 5F72C 4XJ8A 4QN7A 2FHRA 2H2UA 4D4UA 1V0EA 4XIKA 4H52A 3ZGDA 1A14N 2DG1A 4YW5A 3G4HA 1RWLA 3B7EA 1ZGKA 4GDJA 1NSBA 1MS0A 4YW4A 3HRPA 3K36A 4MWJA 1NN2A 4H53A 3Q6PA 4MWRA 4GDIA 1XOEA 1NMCA 3I1CA 3INBA 3HLIA 3K3AA 1Z4XA 2AGSA 4B7JA 4O5SA 3SRGA 2FLUX 1V3BA 3O9JA 2BZDA 3VNGA 1E8UA 4GZSA 5HX0A 4QN4A 2IAUA 4XJWA 4XJRA 4Q1UA 3S94A 1L7GA 3NN9A 2QWKA 2C4AA 1NCDN 4WA3A 2WOZA 2GVVA 2AEPA 3SOVA 4KS3A 3WWAA 3SOBB 3A71A 3VNHA 5GX2A 4FOYA 1F8DA 5HUNA 3FVZA 4FOWA 4XOGA 2ZWAA 1INHA 3NSSA 4M4UA 4FPGA 2VSMA 4I00A 1SUUA 2SIMA 4GZOA 2XN4A 3ALWA 2ZW9A 4K1JA 1NPEA 5HUGA 3K38A 4YZ4A 3K39A 1DIMA 3D11A 1IJQA 3SALA 1B9TA 4XJAA 1EUTA 4KS1A 2XCYA 4FPYA 3TIAA 4QN3A 1INGA 1F8BA 2F11A 2YA8A 4AHAA 4MZAA 4R40A 3OPZA 1EUUA 3DR2A 1V04A 2HU0A 2FPCA 2V91A 2F24A 1V0ZA 1B9SA 2YDTA 1W21A 2P4OA 5D9DA 2GVXA 3UC1A 4KS2A 4FPLA 2HTUA 4GN7A 3HLHA 4K1IA 2HTYA 4MWWA 1NNBA 1MS9A 3LI4A 4GB1A 1F8EA 4HHOA 1A4GA 2JKBA 2A75A 4X49A 5FZNA 4YZ1A 4GZQA 1QLGA 5B2CA 4ZY3A 3PJQA 3TI6A 1Q7FA 4XHBA 4XYXA 4NC5A 1SLLA 3NO0A 4HZZA 1Z4ZA 5D9BA 2F13A 1IVEA 1K32A 4K1KA 4C1YA 4YY8A 5GX4A 2HTWA 2IARA 4FPKA 5M1ZA 2HTQA 4AH4A 2VAQA 1SLIA 2ZB6A 3WW9A 1V3DA 3AMRA 4WEFA 2QWCA 2YA5A 4CPNA 3WDZA 1W0PA 2HT5A 1VCJA 4ZLRA 2VPJA 4HZWA 4B7QA 4FPHA 4FJ6A 5EO7A 2F26A 2C4LA 4WA5A 1RWIA 3GVKA 3T1EA 1NCCN 1W8OA 4X6KA 1NMAN 1Z50A 1CRZA 3A72A 1USXA 1WCSA 3BEQA 4FVKA 4HIZA 1H6LA 1POOA 2AH2A 5HUMA 1N1YA 1S1DA 2DG0A 1PJXA 5EX7A 1INFA 4K3YA 2QWHA 4FPOB 2VWDA 4YZ2A 1U6DX 1C5KA 2Z32A 2QE8A 4MC7A 4D52C 3L6VA 4QNPA 3G4EA 4KS4A 3ZGCA 4Q6KA 2HU4A 3TI3A 3TIBA 1N6EA 2YA4A 4FOQA 1Z4VA 1MS8A 2BATA 4BBWA 3SLIA 4UOUA 2QWIA 4YZ5A 3KYAA 2GHSA 4ZGCA 1S18A 2YA7A 4MX0A 4L7DA 4SLIA 5FNQA 2QWFA 1W0OA 4YW2A 2W20A 1IUBA 2W8BA 3CKZA 1BJIA 4CPMA 1EUSA 1MWEA 4XJ9A 1B9VA 3IAXA 4CPLA 3U0SA 4M4VA 1IUCA 3V64C 1NMBN 4IFNX 7NN9A 3O9KA 2QWEA 1NCAN 4JMLA 4D52B 5B2DA 1IVGA 3DASA 1L7FA 3P5BL 4KS5A 4QN5A 1W8NA 4CPZA 4HW6A 2QWGA 1NCBN 4B7RA 5F9TA 4XJUA 4XILA 1E8TA 4CSDA 4FP2A 4MWQA 1V3CA 1USRA 1NSCA 4XMBA 4AGIA 1DILA 4B7NA 1A4QA 4IMBA 2F25A 1MS5A 3K37A 4GNAA 4N1BA 1NSDA 4YW3A 2F29A 2IVZA 2VVZA 3Q6TA 1OFZA 2QWAA 2HTVA 2QWDA 3II7A 2ISMA 4IFLX 4MWUA 4XJQA 1MZ5A 4GZXA 4CPYA 4XE9A 1N6DA 2DYHA 3CL0A 2W38A 1INWA 1INVA 4GZTA 4L7CA 4M3MA 4MWLA 1CRUA 1Z4WA 3B69A 4HHQA 4PWZA 1IVCA 1W20A 4O5TA 4K1HA 3JU4A 1VCUA 3SREA 1KITA 3O4PA 4ASCA 2IAOA 4YW1A 2IAXA 5FZJA 1X2JA 1ZI0A 2XZJA 4WEGA 4GZPA 5EO8A 4C1YB 4CHBA 2FP8A 5NN9A 4J9TA 1NNAA 1S0JA 2GVUA 5FNTA 4CPOA 2CMLA 2F28A 5FWWA 2HTRA 2IAVA 2VW1A 2GVWA 2VSKA 3S8ZA 4A0PA 4MJUA 4WA4A 1MZ6A 4DG6A 3AMSA 4MWVA 4IYGA 2G8SA 2IATA 5FNUA 1SNTA 5GTQA 1MS1A 5HUKA 4XMAA 6NN9A 3SILA 3LI5A 1N1TA 4FPCA 1N1SA 3KGGA 5FNRA 2IAWA 1S0IA 4IQKA 4XHXA 4FP3A 1W1XA 5FNSA 1L7HA 4FPJA 3GVJA 3SOQA 3D12A 3W09A 1N7DA 1IVBA 1E8VA 2IAQA 4D8SA 1X2RA 4X47A 2BERA 3H72A 2FP9A 3WN7A 2HT8A 2YA6A 2F10A 1C9UA 4L7BA 1XOGA 4JF7A 3SANA 2F27A 2AEQA 2OJHA 1V0FA 4MZEA 5H47A 3GVLA 1MS3A 3TC9A 5GX1A 1NNCA 2W5OA 1INXA 3H73A 3CL2A 4YZ3A 2RKCA 4HZXA 4MJVA 2H2NA 1INYA 4FPFA 4D52A 4GN8A 4XMIA 4CH9A 2IAPA 2ZB5A 3ALXA 3TICA 2B8HA 2XZIA 2W8BB 4QN6A 1E1AA 1Z4YA 2DSOA 2POOA 4GZWA 4MWYA 2HQSA 4G3NA 1V3EA 5GX3A 3TI4A 2VW0A 1IVDA 3FW0A 4NCSA 3V65B 2IASA 2ZZKA 4XIOA 4XJZA 2VW2A 4X4AA 2W5NA 4FPEA 2VK5A 5D9CA 2SILA 2VK6A 4HZVA 5CGJA 3Q6KA 2SLIA 3CYEA 4IFJA 3S8VA 5JYYA 3H6JA 4M4NA 4FOVA 4GJTA 3LI3A 3TI5A 4FZHA 2X9MA 1MS4A 3A9HA 1MR5A 1QBIA 1SO7A 2XZKA 3V1SA 4NN9A 3TI8A 2BF6A 4DGRA 4GEZA 4FQ4A 1CVMA 3H71A 2HT7A 4HZYA 4GN9A 2YDPA 1F8CA 1EURA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 5FNQ A;  5FZJ A;  1U6D X;  3ZGD A;  1X2J A;  4IFJ A;  2Z32 A;  2XN4 A;  4CHB A;  3II7 A;  1ZGK A;  2ZW9 A;  4IFL X;  4L7B A;  4YY8 A;  5FNT A;  2DYH A;  2WOZ A;  4IN4 A;  5FNR A;  3ZGC A;  4IQK A;  4XMB A;  5FNS A;  3VNH A;  4L7C A;  3ADE A;  4ASC A;  4IFN X;  5F72 C;  3WDZ A;  2ZZK A;  4N1B A;  5FZN A;  5FNU A;  2ZWA A;  1X2R A;  4ZY3 A;  2VPJ A;  2FLU X;  3WN7 A;  4ZGC A;  3VNG A;  4CH9 A;  5CGJ A;  4L7D A; 
#chains in the Genus database with same CATH topology
 5GX5 A;  1WP5 A;  1WCQ A;  2QWB A;  4B7M A;  1N1V A;  2FPB A;  1IVF A;  2F0Z A;  4GNC A;  1V2I A;  4GNB A;  1CQ1 A;  3S2K A;  3BYC A;  4IN4 A;  2QWJ A;  4UF7 A;  2F12 A;  4AGT A;  3A9G A;  2VK7 A;  4MWX A;  1N6F A;  3ADE A;  3E5Z A;  5F72 C;  4XJ8 A;  4QN7 A;  2FHR A;  2H2U A;  4D4U A;  1V0E A;  4XIK A;  4H52 A;  3ZGD A;  1A14 N;  2DG1 A;  4YW5 A;  3G4H A;  1RWL A;  3B7E A;  1ZGK A;  4GDJ A;  1NSB A;  1MS0 A;  4YW4 A;  3HRP A;  3K36 A;  4MWJ A;  1NN2 A;  4H53 A;  3Q6P A;  4MWR A;  4GDI A;  1XOE A;  1NMC A;  3I1C A;  3INB A;  3HLI A;  3K3A A;  1Z4X A;  2AGS A;  4B7J A;  4O5S A;  3SRG A;  2FLU X;  1V3B A;  3O9J A;  2BZD A;  3VNG A;  1E8U A;  4GZS A;  5HX0 A;  4QN4 A;  2IAU A;  4XJW A;  4XJR A;  4Q1U A;  3S94 A;  1L7G A;  3NN9 A;  2QWK A;  2C4A A;  1NCD N;  4WA3 A;  2WOZ A;  2GVV A;  2AEP A;  3SOV A;  4KS3 A;  3WWA A;  3SOB B;  3A71 A;  3VNH A;  5GX2 A;  4FOY A;  1F8D A;  5HUN A;  3FVZ A;  4FOW A;  4XOG A;  2ZWA A;  1INH A;  3NSS A;  4M4U A;  4FPG A;  2VSM A;  4I00 A;  1SUU A;  2SIM A;  4GZO A;  2XN4 A;  3ALW A;  2ZW9 A;  4K1J A;  1NPE A;  5HUG A;  3K38 A;  4YZ4 A;  3K39 A;  1DIM A;  3D11 A;  1IJQ A;  3SAL A;  1B9T A;  4XJA A;  1EUT A;  4KS1 A;  2XCY A;  4FPY A;  3TIA A;  4QN3 A;  1ING A;  1F8B A;  2F11 A;  2YA8 A;  4AHA A;  4MZA A;  4R40 A;  3OPZ A;  1EUU A;  3DR2 A;  1V04 A;  2HU0 A;  2FPC A;  2V91 A;  2F24 A;  1V0Z A;  1B9S A;  2YDT A;  1W21 A;  2P4O A;  5D9D A;  2GVX A;  3UC1 A;  4KS2 A;  4FPL A;  2HTU A;  4GN7 A;  3HLH A;  4K1I A;  2HTY A;  4MWW A;  1NNB A;  1MS9 A;  3LI4 A;  4GB1 A;  1F8E A;  4HHO A;  1A4G A;  2JKB A;  2A75 A;  4X49 A;  5FZN A;  4YZ1 A;  4GZQ A;  1QLG A;  5B2C A;  4ZY3 A;  3PJQ A;  3TI6 A;  1Q7F A;  4XHB A;  4XYX A;  4NC5 A;  1SLL A;  3NO0 A;  4HZZ A;  1Z4Z A;  5D9B A;  2F13 A;  1IVE A;  1K32 A;  4K1K A;  4C1Y A;  4YY8 A;  5GX4 A;  2HTW A;  2IAR A;  4FPK A;  5M1Z A;  2HTQ A;  4AH4 A;  2VAQ A;  1SLI A;  2ZB6 A;  3WW9 A;  1V3D A;  3AMR A;  4WEF A;  2QWC A;  2YA5 A;  4CPN A;  3WDZ A;  1W0P A;  2HT5 A;  1VCJ A;  4ZLR A;  2VPJ A;  4HZW A;  4B7Q A;  4FPH A;  4FJ6 A;  5EO7 A;  2F26 A;  2C4L A;  4WA5 A;  1RWI A;  3GVK A;  3T1E A;  1NCC N;  1W8O A;  4X6K A;  1NMA N;  1Z50 A;  1CRZ A;  3A72 A;  1USX A;  1WCS A;  3BEQ A;  4FVK A;  4HIZ A;  1H6L A;  1POO A;  2AH2 A;  5HUM A;  1N1Y A;  1S1D A;  2DG0 A;  1PJX A;  5EX7 A;  1INF A;  4K3Y A;  2QWH A;  4FPO B;  2VWD A;  4YZ2 A;  1U6D X;  1C5K A;  2Z32 A;  2QE8 A;  4MC7 A;  4D52 C;  3L6V A;  4QNP A;  3G4E A;  4KS4 A;  3ZGC A;  4Q6K A;  2HU4 A;  3TI3 A;  3TIB A;  1N6E A;  2YA4 A;  4FOQ A;  1Z4V A;  1MS8 A;  2BAT A;  4BBW A;  3SLI A;  4UOU A;  2QWI A;  4YZ5 A;  3KYA A;  2GHS A;  4ZGC A;  1S18 A;  2YA7 A;  4MX0 A;  4L7D A;  4SLI A;  5FNQ A;  2QWF A;  1W0O A;  4YW2 A;  2W20 A;  1IUB A;  2W8B A;  3CKZ A;  1BJI A;  4CPM A;  1EUS A;  1MWE A;  4XJ9 A;  1B9V A;  3IAX A;  4CPL A;  3U0S A;  4M4V A;  1IUC A;  3V64 C;  1NMB N;  4IFN X;  7NN9 A;  3O9K A;  2QWE A;  1NCA N;  4JML A;  4D52 B;  5B2D A;  1IVG A;  3DAS A;  1L7F A;  3P5B L;  4KS5 A;  4QN5 A;  1W8N A;  4CPZ A;  4HW6 A;  2QWG A;  1NCB N;  4B7R A;  5F9T A;  4XJU A;  4XIL A;  1E8T A;  4CSD A;  4FP2 A;  4MWQ A;  1V3C A;  1USR A;  1NSC A;  4XMB A;  4AGI A;  1DIL A;  4B7N A;  1A4Q A;  4IMB A;  2F25 A;  1MS5 A;  3K37 A;  4GNA A;  4N1B A;  1NSD A;  4YW3 A;  2F29 A;  2IVZ A;  2VVZ A;  3Q6T A;  1OFZ A;  2QWA A;  2HTV A;  2QWD A;  3II7 A;  2ISM A;  4IFL X;  4MWU A;  4XJQ A;  1MZ5 A;  4GZX A;  4CPY A;  4XE9 A;  1N6D A;  2DYH A;  3CL0 A;  2W38 A;  1INW A;  1INV A;  4GZT A;  4L7C A;  4M3M A;  4MWL A;  1CRU A;  1Z4W A;  3B69 A;  4HHQ A;  4PWZ A;  1IVC A;  1W20 A;  4O5T A;  4K1H A;  3JU4 A;  1VCU A;  3SRE A;  1KIT A;  3O4P A;  4ASC A;  2IAO A;  4YW1 A;  2IAX A;  5FZJ A;  1X2J A;  1ZI0 A;  2XZJ A;  4WEG A;  4GZP A;  5EO8 A;  4C1Y B;  4CHB A;  2FP8 A;  5NN9 A;  4J9T A;  1NNA A;  1S0J A;  2GVU A;  5FNT A;  4CPO A;  2CML A;  2F28 A;  5FWW A;  2HTR A;  2IAV A;  2VW1 A;  2GVW A;  2VSK A;  3S8Z A;  4A0P A;  4MJU A;  4WA4 A;  1MZ6 A;  4DG6 A;  3AMS A;  4MWV A;  4IYG A;  2G8S A;  2IAT A;  5FNU A;  1SNT A;  5GTQ A;  1MS1 A;  5HUK A;  4XMA A;  6NN9 A;  3SIL A;  3LI5 A;  1N1T A;  4FPC A;  1N1S A;  3KGG A;  5FNR A;  2IAW A;  1S0I A;  4IQK A;  4XHX A;  4FP3 A;  1W1X A;  5FNS A;  1L7H A;  4FPJ A;  3GVJ A;  3SOQ A;  3D12 A;  3W09 A;  1N7D A;  1IVB A;  1E8V A;  2IAQ A;  4D8S A;  1X2R A;  4X47 A;  2BER A;  3H72 A;  2FP9 A;  3WN7 A;  2HT8 A;  2YA6 A;  2F10 A;  1C9U A;  4L7B A;  1XOG A;  4JF7 A;  3SAN A;  2F27 A;  2AEQ A;  2OJH A;  1V0F A;  4MZE A;  5H47 A;  3GVL A;  1MS3 A;  3TC9 A;  5GX1 A;  1NNC A;  2W5O A;  1INX A;  3H73 A;  3CL2 A;  4YZ3 A;  2RKC A;  4HZX A;  4MJV A;  2H2N A;  1INY A;  4FPF A;  4D52 A;  4GN8 A;  4XMI A;  4CH9 A;  2IAP A;  2ZB5 A;  3ALX A;  3TIC A;  2B8H A;  2XZI A;  2W8B B;  4QN6 A;  1E1A A;  1Z4Y A;  2DSO A;  2POO A;  4GZW A;  4MWY A;  2HQS A;  4G3N A;  1V3E A;  5GX3 A;  3TI4 A;  2VW0 A;  1IVD A;  3FW0 A;  4NCS A;  3V65 B;  2IAS A;  2ZZK A;  4XIO A;  4XJZ A;  2VW2 A;  4X4A A;  2W5N A;  4FPE A;  2VK5 A;  5D9C A;  2SIL A;  2VK6 A;  4HZV A;  5CGJ A;  3Q6K A;  2SLI A;  3CYE A;  4IFJ A;  3S8V A;  5JYY A;  3H6J A;  4M4N A;  4FOV A;  4GJT A;  3LI3 A;  3TI5 A;  4FZH A;  2X9M A;  1MS4 A;  3A9H A;  1MR5 A;  1QBI A;  1SO7 A;  2XZK A;  3V1S A;  4NN9 A;  3TI8 A;  2BF6 A;  4DGR A;  4GEZ A;  4FQ4 A;  1CVM A;  3H71 A;  2HT7 A;  4HZY A;  4GN9 A;  2YDP A;  1F8C A;  1EUR A; 
#chains in the Genus database with same CATH homology
 5FNQ A;  5FZJ A;  1U6D X;  3ZGD A;  1X2J A;  4IFJ A;  2Z32 A;  2XN4 A;  4CHB A;  3II7 A;  1ZGK A;  2ZW9 A;  4IFL X;  4L7B A;  4YY8 A;  5FNT A;  2DYH A;  2WOZ A;  4IN4 A;  5FNR A;  3ZGC A;  4IQK A;  4XMB A;  5FNS A;  3VNH A;  4L7C A;  3ADE A;  4ASC A;  4IFN X;  5F72 C;  3WDZ A;  2ZZK A;  4N1B A;  5FZN A;  5FNU A;  2ZWA A;  1X2R A;  4ZY3 A;  2VPJ A;  2FLU X;  3WN7 A;  4ZGC A;  3VNG A;  4CH9 A;  5CGJ A;  4L7D A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3II7A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations