3NO0 | Genus

Total Genus 82

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	82
sequence length	276
structure length	275
Chain Sequence	GSITVAVLQDGSIIPVEELPLEKAPVVNILRVPFTEGLFLVSNRGRVYWIAGSQALQGSKVSLKSREEKIVGAFIREKFGNRLLLATKKGYVKKIPLAEFEYKAQGMPIIKLTEGDEVVSIASSVDETHILLFTKKGRVARFSVREVPPSTPGARGVQGIKLEKNDETSGLRIWNGEPYLLVITAKGRVKKISHEEIPKTNRGVKGTEVSGTKDTLVDLIPIKEEVELLITTKNGKAFYDKINQKDIPLSTKKSIPRRWKLEDDEIIKVVIKKSE

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Isomerase
source organism	Aquifex aeolicus
publication title	A naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogs. pubmed doi rcsb
molecule keywords	DNA gyrase subunit A
total genus	82
structure length	275
sequence length	276
chains with identical sequence	B, C
ec nomenclature	ec 5.99.1.3: Transferred entry: 5.6.2.3.
pdb deposition date	2010-06-24

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF03989	DNA_gyraseA_C	DNA gyrase C-terminal domain, beta-propeller

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.120.10.90	Mainly Beta	6 Propeller	Neuraminidase	DNA gyrase/topoisomerase IV, subunit A, C-terminal	3no0A00

1ZI0A 3NO0A 1SUUA 3L6VA 3UC1A 4G3NA 1WP5A
chains in the Genus database with same CATH superfamily

4IYGA 5FNTA 3LI4A 2HQSA 4H53A 1DIMA 4B7JA 3H73A 3V64C 4QNPA 4YZ1A 2YA8A 1N1VA 1Z4ZA 2FPBA 2XN4A 4WA4A 3V65B 2VW2A 7NN9A 1W1XA 4N1BA 1E8UA 3E5ZA 2VW0A 4D4UA 4M4NA 2AEPA 2AEQA 1V3DA 3FW0A 2POOA 1MZ6A 4FPOB 4XHXA 4FPEA 1U6DX 5D9CA 1CRUA 1B9SA 4MWLA 4GNAA 4MWQA 2GVUA 4K1IA 3ZGDA 2HT5A 3B7EA 1MS5A 1NMAN 3II7A 2QWKA 4CPOA 2C4AA 2IARA 3S94A 3TIBA 2ZB6A 1USRA 1CVMA 3ALWA 4FP2A 3SANA 4CPLA 3P5BL 1N7DA 1ZGKA 4AHAA 4K1KA 5H47A 4DGRA 1MS1A 4FPYA 4I00A 3WDZA 1V3CA 3S8ZA 2F29A 5FNUA 4YW5A 2QWAA 1NPEA 2VAQA 5D9BA 4YZ4A 4L7DA 2IASA 4GDJA 1V3EA 3O9KA 4GZWA 5FNRA 4FPKA 3HLIA 1PJXA 4FOQA 1N1TA 2YA6A 2FHRA 4X6KA 4D52C 3A9GA 4XJUA 4CHBA 3DR2A 1E8VA 2QWGA 1V0FA 3KYAA 3L6VA 4GN9A 1BJIA 1MZ5A 5EO7A 4FPLA 2P4OA 4C1YB 4MZEA 3CYEA 2RKCA 4XIOA 1W20A 1VCUA 3AMRA 4JF7A 1NMBN 2H2NA 1INFA 3NSSA 4SLIA 4CPYA 1QLGA 4IMBA 5GX1A 4XILA 2HT7A 1L7HA 4YY8A 3V1SA 1NSDA 1QBIA 4HIZA 2BZDA 5B2DA 1KITA 3W09A 3DASA 2YDTA 4GJTA 4HZWA 1SUUA 4QN5A 4FPGA 4MWXA 2H2UA 2C4LA 2YA4A 1F8BA 2JKBA 1INGA 1V0ZA 1V2IA 4X4AA 2HTRA 2F28A 4CSDA 4GDIA 1Z4WA 2A75A 2W8BA 3SOQA 2F27A 3CL2A 4GZXA 5HUGA 4KS5A 5EX7A 4GZPA 4J9TA 4D52A 1NNCA 1Z50A 4GZOA 2BATA 4L7CA 3INBA 4UOUA 1S0IA 5FNSA 4FZHA 1Z4VA 5F72C 2IAPA 4QN3A 4FQ4A 2IAVA 1IVCA 2VK5A 4MWWA 2GHSA 2VK6A 2QWIA 3NN9A 3UC1A 2CMLA 4GNBA 1DILA 1B9VA 3GVJA 2VVZA 1IJQA 3Q6KA 4M3MA 4WA5A 4FOYA 2IAOA 2AGSA 4FVKA 3S8VA 3SREA 4XIKA 3O9JA 4IQKA 2W8BB 4FPCA 1H6LA 2F26A 4XJAA 1C5KA 1CQ1A 1INXA 4O5TA 3D12A 4B7MA 3TI3A 2HT8A 1MR5A 1IVDA 4FP3A 1V3BA 3CL0A 3PJQA 3K38A 4MJVA 1EURA 2XCYA 2AH2A 1V0EA 3BYCA 1C9UA 2QE8A 1Q7FA 3HLHA 4MWYA 1NSBA 3AMSA 2DG1A 3K39A 3WWAA 5GX2A 1NNAA 1V04A 4K3YA 4K1HA 2VWDA 1INYA 4QN4A 3TICA 4XJRA 1IUCA 4YW1A 4YW2A 1WCQA 2DYHA 4DG6A 4XHBA 1X2RA 1XOGA 1Z4YA 2HTYA 3H72A 2B8HA 2F10A 3LI5A 4HZVA 2HTQA 1RWIA 3A72A 3GVKA 1POOA 4IFLX 4KS4A 5GX3A 1RWLA 1F8EA 4WA3A 2SILA 4A0PA 1EUSA 5HUKA 2BERA 4CPZA 3G4HA 4HW6A 4FPFA 2WOZA 1A4GA 4KS2A 1IUBA 2SIMA 4HHQA 2F25A 4PWZA 2HU0A 3H6JA 1NNBA 1EUUA 2QWDA 2QWHA 4MWJA 2QWBA 1X2JA 2GVWA 3CKZA 1ZI0A 3SRGA 1W21A 4XOGA 4AH4A 4O5SA 1NCCN 4WEFA 5FNQA 4JMLA 4XMBA 4CPMA 3S2KA 4YZ3A 2FP8A 4Q1UA 4XMAA 5D9DA 4X49A 1Z4XA 1VCJA 4ZY3A 4XJ9A 1MS8A 1N1SA 5HUMA 2V91A 4FOVA 5M1ZA 4MWVA 2FP9A 3TI6A 2VK7A 2ZZKA 4WEGA 1MS0A 1S0JA 2HTVA 2W20A 3D11A 2XZKA 4BBWA 4IN4A 4UF7A 4X47A 4NN9A 2DG0A 4MZAA 2HTWA 1L7GA 3BEQA 4QN7A 2VW1A 4L7BA 3TIAA 1NCBN 2QWCA 1W8OA 2BF6A 1NN2A 3ADEA 2QWJA 1IVBA 4ZLRA 5F9TA 5GTQA 4D8SA 4HZYA 3IAXA 4XYXA 1INVA 2G8SA 4M4VA 3SOBB 3ZGCA 3NO0A 4GN7A 2DSOA 1E8TA 3SALA 1F8DA 3GVLA 1A4QA 4HZXA 4CH9A 2IAXA 4KS3A 1NCAN 1MWEA 2W5OA 1B9TA 3A71A 4QN6A 1EUTA 5FZJA 2HU4A 4MX0A 4YZ2A 4GZSA 4D52B 3HRPA 5GX5A 2SLIA 2F24A 1W8NA 2IAQA 1SLIA 2FLUX 4HZZA 2ISMA 2Z32A 1INWA 4Q6KA 3WN7A 4MWRA 5GX4A 2VSMA 4YW3A 1W0PA 4C1YA 3B69A 1S18A 2VPJA 5NN9A 2ZWAA 3Q6TA 4NC5A 1NSCA 3Q6PA 1NCDN 2QWFA 2YDPA 2ZB5A 3K3AA 2F12A 4CPNA 2IAWA 4GZTA 4MJUA 5JYYA 4K1JA 2F13A 1XOEA 1K32A 5HX0A 2W5NA 4YZ5A 4ASCA 3O4PA 5EO8A 2YA7A 3T1EA 1E1AA 1F8CA 1IVFA 5FZNA 1N6FA 3FVZA 4GN8A 3KGGA 2IATA 4NCSA 1USXA 3TI4A 3H71A 1MS4A 3K37A 1INHA 2XZJA 4XJZA 4YW4A 1W0OA 3SOVA 3K36A 4GEZA 4ZGCA 1IVEA 1SO7A 2X9MA 4XJWA 4MWUA 2OJHA 4B7NA 1S1DA 3TC9A 3LI3A 2QWEA 4FOWA 4XJ8A 1N6DA 4XJQA 4HHOA 4XMIA 3SILA 2IAUA 3OPZA 3VNGA 1SNTA 1IVGA 1N1YA 1N6EA 2FPCA 4GNCA 3VNHA 5B2CA 1WCSA 3I1CA 3A9HA 3SLIA 4AGIA 4FPHA 4H52A 3U0SA 3JU4A 4G3NA 4R40A 1WP5A 4IFJA 1MS3A 4B7RA 1NMCA 2GVVA 2VSKA 2YA5A 5HUNA 4FPJA 1OFZA 2F0ZA 6NN9A 1L7FA 4B7QA 4MC7A 4KS1A 4GZQA 4AGTA 2ZW9A 1A14N 3WW9A 4GB1A 4M4UA 3G4EA 2IVZA 1MS9A 2GVXA 4FJ6A 4XE9A 5CGJA 5FWWA 2XZIA 2F11A 2W38A 1CRZA 3TI8A 3ALXA 2HTUA 1SLLA 3TI5A 4IFNX
chains in the Genus database with same CATH topology

1ZI0A 3NO0A 1SUUA 3L6VA 3UC1A 4G3NA 1WP5A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1ZI0 A;  3NO0 A;  1SUU A;  3L6V A;  3UC1 A;  4G3N A;  1WP5 A; 
#chains in the Genus database with same CATH topology
 4IYG A;  5FNT A;  3LI4 A;  2HQS A;  4H53 A;  1DIM A;  4B7J A;  3H73 A;  3V64 C;  4QNP A;  4YZ1 A;  2YA8 A;  1N1V A;  1Z4Z A;  2FPB A;  2XN4 A;  4WA4 A;  3V65 B;  2VW2 A;  7NN9 A;  1W1X A;  4N1B A;  1E8U A;  3E5Z A;  2VW0 A;  4D4U A;  4M4N A;  2AEP A;  2AEQ A;  1V3D A;  3FW0 A;  2POO A;  1MZ6 A;  4FPO B;  4XHX A;  4FPE A;  1U6D X;  5D9C A;  1CRU A;  1B9S A;  4MWL A;  4GNA A;  4MWQ A;  2GVU A;  4K1I A;  3ZGD A;  2HT5 A;  3B7E A;  1MS5 A;  1NMA N;  3II7 A;  2QWK A;  4CPO A;  2C4A A;  2IAR A;  3S94 A;  3TIB A;  2ZB6 A;  1USR A;  1CVM A;  3ALW A;  4FP2 A;  3SAN A;  4CPL A;  3P5B L;  1N7D A;  1ZGK A;  4AHA A;  4K1K A;  5H47 A;  4DGR A;  1MS1 A;  4FPY A;  4I00 A;  3WDZ A;  1V3C A;  3S8Z A;  2F29 A;  5FNU A;  4YW5 A;  2QWA A;  1NPE A;  2VAQ A;  5D9B A;  4YZ4 A;  4L7D A;  2IAS A;  4GDJ A;  1V3E A;  3O9K A;  4GZW A;  5FNR A;  4FPK A;  3HLI A;  1PJX A;  4FOQ A;  1N1T A;  2YA6 A;  2FHR A;  4X6K A;  4D52 C;  3A9G A;  4XJU A;  4CHB A;  3DR2 A;  1E8V A;  2QWG A;  1V0F A;  3KYA A;  3L6V A;  4GN9 A;  1BJI A;  1MZ5 A;  5EO7 A;  4FPL A;  2P4O A;  4C1Y B;  4MZE A;  3CYE A;  2RKC A;  4XIO A;  1W20 A;  1VCU A;  3AMR A;  4JF7 A;  1NMB N;  2H2N A;  1INF A;  3NSS A;  4SLI A;  4CPY A;  1QLG A;  4IMB A;  5GX1 A;  4XIL A;  2HT7 A;  1L7H A;  4YY8 A;  3V1S A;  1NSD A;  1QBI A;  4HIZ A;  2BZD A;  5B2D A;  1KIT A;  3W09 A;  3DAS A;  2YDT A;  4GJT A;  4HZW A;  1SUU A;  4QN5 A;  4FPG A;  4MWX A;  2H2U A;  2C4L A;  2YA4 A;  1F8B A;  2JKB A;  1ING A;  1V0Z A;  1V2I A;  4X4A A;  2HTR A;  2F28 A;  4CSD A;  4GDI A;  1Z4W A;  2A75 A;  2W8B A;  3SOQ A;  2F27 A;  3CL2 A;  4GZX A;  5HUG A;  4KS5 A;  5EX7 A;  4GZP A;  4J9T A;  4D52 A;  1NNC A;  1Z50 A;  4GZO A;  2BAT A;  4L7C A;  3INB A;  4UOU A;  1S0I A;  5FNS A;  4FZH A;  1Z4V A;  5F72 C;  2IAP A;  4QN3 A;  4FQ4 A;  2IAV A;  1IVC A;  2VK5 A;  4MWW A;  2GHS A;  2VK6 A;  2QWI A;  3NN9 A;  3UC1 A;  2CML A;  4GNB A;  1DIL A;  1B9V A;  3GVJ A;  2VVZ A;  1IJQ A;  3Q6K A;  4M3M A;  4WA5 A;  4FOY A;  2IAO A;  2AGS A;  4FVK A;  3S8V A;  3SRE A;  4XIK A;  3O9J A;  4IQK A;  2W8B B;  4FPC A;  1H6L A;  2F26 A;  4XJA A;  1C5K A;  1CQ1 A;  1INX A;  4O5T A;  3D12 A;  4B7M A;  3TI3 A;  2HT8 A;  1MR5 A;  1IVD A;  4FP3 A;  1V3B A;  3CL0 A;  3PJQ A;  3K38 A;  4MJV A;  1EUR A;  2XCY A;  2AH2 A;  1V0E A;  3BYC A;  1C9U A;  2QE8 A;  1Q7F A;  3HLH A;  4MWY A;  1NSB A;  3AMS A;  2DG1 A;  3K39 A;  3WWA A;  5GX2 A;  1NNA A;  1V04 A;  4K3Y A;  4K1H A;  2VWD A;  1INY A;  4QN4 A;  3TIC A;  4XJR A;  1IUC A;  4YW1 A;  4YW2 A;  1WCQ A;  2DYH A;  4DG6 A;  4XHB A;  1X2R A;  1XOG A;  1Z4Y A;  2HTY A;  3H72 A;  2B8H A;  2F10 A;  3LI5 A;  4HZV A;  2HTQ A;  1RWI A;  3A72 A;  3GVK A;  1POO A;  4IFL X;  4KS4 A;  5GX3 A;  1RWL A;  1F8E A;  4WA3 A;  2SIL A;  4A0P A;  1EUS A;  5HUK A;  2BER A;  4CPZ A;  3G4H A;  4HW6 A;  4FPF A;  2WOZ A;  1A4G A;  4KS2 A;  1IUB A;  2SIM A;  4HHQ A;  2F25 A;  4PWZ A;  2HU0 A;  3H6J A;  1NNB A;  1EUU A;  2QWD A;  2QWH A;  4MWJ A;  2QWB A;  1X2J A;  2GVW A;  3CKZ A;  1ZI0 A;  3SRG A;  1W21 A;  4XOG A;  4AH4 A;  4O5S A;  1NCC N;  4WEF A;  5FNQ A;  4JML A;  4XMB A;  4CPM A;  3S2K A;  4YZ3 A;  2FP8 A;  4Q1U A;  4XMA A;  5D9D A;  4X49 A;  1Z4X A;  1VCJ A;  4ZY3 A;  4XJ9 A;  1MS8 A;  1N1S A;  5HUM A;  2V91 A;  4FOV A;  5M1Z A;  4MWV A;  2FP9 A;  3TI6 A;  2VK7 A;  2ZZK A;  4WEG A;  1MS0 A;  1S0J A;  2HTV A;  2W20 A;  3D11 A;  2XZK A;  4BBW A;  4IN4 A;  4UF7 A;  4X47 A;  4NN9 A;  2DG0 A;  4MZA A;  2HTW A;  1L7G A;  3BEQ A;  4QN7 A;  2VW1 A;  4L7B A;  3TIA A;  1NCB N;  2QWC A;  1W8O A;  2BF6 A;  1NN2 A;  3ADE A;  2QWJ A;  1IVB A;  4ZLR A;  5F9T A;  5GTQ A;  4D8S A;  4HZY A;  3IAX A;  4XYX A;  1INV A;  2G8S A;  4M4V A;  3SOB B;  3ZGC A;  3NO0 A;  4GN7 A;  2DSO A;  1E8T A;  3SAL A;  1F8D A;  3GVL A;  1A4Q A;  4HZX A;  4CH9 A;  2IAX A;  4KS3 A;  1NCA N;  1MWE A;  2W5O A;  1B9T A;  3A71 A;  4QN6 A;  1EUT A;  5FZJ A;  2HU4 A;  4MX0 A;  4YZ2 A;  4GZS A;  4D52 B;  3HRP A;  5GX5 A;  2SLI A;  2F24 A;  1W8N A;  2IAQ A;  1SLI A;  2FLU X;  4HZZ A;  2ISM A;  2Z32 A;  1INW A;  4Q6K A;  3WN7 A;  4MWR A;  5GX4 A;  2VSM A;  4YW3 A;  1W0P A;  4C1Y A;  3B69 A;  1S18 A;  2VPJ A;  5NN9 A;  2ZWA A;  3Q6T A;  4NC5 A;  1NSC A;  3Q6P A;  1NCD N;  2QWF A;  2YDP A;  2ZB5 A;  3K3A A;  2F12 A;  4CPN A;  2IAW A;  4GZT A;  4MJU A;  5JYY A;  4K1J A;  2F13 A;  1XOE A;  1K32 A;  5HX0 A;  2W5N A;  4YZ5 A;  4ASC A;  3O4P A;  5EO8 A;  2YA7 A;  3T1E A;  1E1A A;  1F8C A;  1IVF A;  5FZN A;  1N6F A;  3FVZ A;  4GN8 A;  3KGG A;  2IAT A;  4NCS A;  1USX A;  3TI4 A;  3H71 A;  1MS4 A;  3K37 A;  1INH A;  2XZJ A;  4XJZ A;  4YW4 A;  1W0O A;  3SOV A;  3K36 A;  4GEZ A;  4ZGC A;  1IVE A;  1SO7 A;  2X9M A;  4XJW A;  4MWU A;  2OJH A;  4B7N A;  1S1D A;  3TC9 A;  3LI3 A;  2QWE A;  4FOW A;  4XJ8 A;  1N6D A;  4XJQ A;  4HHO A;  4XMI A;  3SIL A;  2IAU A;  3OPZ A;  3VNG A;  1SNT A;  1IVG A;  1N1Y A;  1N6E A;  2FPC A;  4GNC A;  3VNH A;  5B2C A;  1WCS A;  3I1C A;  3A9H A;  3SLI A;  4AGI A;  4FPH A;  4H52 A;  3U0S A;  3JU4 A;  4G3N A;  4R40 A;  1WP5 A;  4IFJ A;  1MS3 A;  4B7R A;  1NMC A;  2GVV A;  2VSK A;  2YA5 A;  5HUN A;  4FPJ A;  1OFZ A;  2F0Z A;  6NN9 A;  1L7F A;  4B7Q A;  4MC7 A;  4KS1 A;  4GZQ A;  4AGT A;  2ZW9 A;  1A14 N;  3WW9 A;  4GB1 A;  4M4U A;  3G4E A;  2IVZ A;  1MS9 A;  2GVX A;  4FJ6 A;  4XE9 A;  5CGJ A;  5FWW A;  2XZI A;  2F11 A;  2W38 A;  1CRZ A;  3TI8 A;  3ALX A;  2HTU A;  1SLL A;  3TI5 A;  4IFN X; 
#chains in the Genus database with same CATH homology
 1ZI0 A;  3NO0 A;  1SUU A;  3L6V A;  3UC1 A;  4G3N A;  1WP5 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3NO0A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations