3NO0A

Aquifex aeolicus type iia topoisomerase c-terminal domain
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
276
structure length
275
Chain Sequence
GSITVAVLQDGSIIPVEELPLEKAPVVNILRVPFTEGLFLVSNRGRVYWIAGSQALQGSKVSLKSREEKIVGAFIREKFGNRLLLATKKGYVKKIPLAEFEYKAQGMPIIKLTEGDEVVSIASSVDETHILLFTKKGRVARFSVREVPPSTPGARGVQGIKLEKNDETSGLRIWNGEPYLLVITAKGRVKKISHEEIPKTNRGVKGTEVSGTKDTLVDLIPIKEEVELLITTKNGKAFYDKINQKDIPLSTKKSIPRRWKLEDDEIIKVVIKKSE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogs.
pubmed doi rcsb
molecule tags Isomerase
source organism Aquifex aeolicus
molecule keywords DNA gyrase subunit A
total genus 82
structure length 275
sequence length 276
chains with identical sequence B, C
ec nomenclature ec 5.99.1.3: Transferred entry: 5.6.2.3.
pdb deposition date 2010-06-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03989 DNA_gyraseA_C DNA gyrase C-terminal domain, beta-propeller
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.90 Mainly Beta 6 Propeller Neuraminidase DNA gyrase/topoisomerase IV, subunit A, C-terminal 3no0A00
1SUUA 4G3NA 1WP5A 3UC1A 3L6VA 3NO0A 1ZI0A
chains in the Genus database with same CATH superfamily
4HHOA 1V3EA 2IAXA 4YW3A 3CKZA 5FWWA 4QN6A 4QN5A 3D12A 4FZHA 2QE8A 3E5ZA 4CHBA 1NPEA 4G3NA 2VSKA 1EUTA 4XMAA 3S2KA 4MC7A 3CL0A 1DILA 2QWIA 2F11A 3ALWA 7NN9A 3WW9A 4FPLA 5EX7A 4K1IA 5JYYA 4XJ8A 4FJ6A 2YA8A 3S8VA 2H2NA 5F72C 2VK6A 2F24A 1V04A 1RWIA 1EUUA 3Q6PA 4AH4A 2QWKA 1NCBN 2AEQA 3TICA 4IMBA 2BATA 2HT8A 4YW1A 1IVCA 2YA6A 2GVWA 1Z4WA 5F9TA 4GEZA 1NCDN 1V3CA 2HT7A 1V0EA 2GVUA 4O5SA 3SOQA 4CSDA 1N7DA 3HRPA 3K39A 3LI5A 2AGSA 2C4LA 4JF7A 1IUBA 3H72A 3A72A 1F8EA 3H6JA 1NSCA 2FPCA 1N6FA 1Z50A 3A9GA 4IFLX 3WDZA 1S1DA 1WP5A 4XJZA 1CVMA 4MWJA 4FPOB 5EO8A 4MWLA 5FNSA 4YY8A 2QWCA 3HLIA 1F8DA 4O5TA 5M1ZA 1KITA 2IATA 1SUUA 2W20A 3I1CA 4CPOA 2SLIA 4YZ5A 5B2CA 2W8BA 1N1SA 1A4GA 3NO0A 3O4PA 4MWXA 1NNAA 1SLLA 4CPLA 4C1YA 4CPMA 4PWZA 1ZI0A 1W1XA 5HUNA 5GX3A 4MWQA 4N1BA 4MWYA 4GNCA 4XJ9A 5HUMA 6NN9A 4X6KA 2B8HA 1S18A 1SLIA 1X2RA 1L7FA 2VK5A 4SLIA 3ZGCA 1XOGA 4GNAA 1NMBN 2F26A 1E1AA 2V91A 4XMIA 4B7NA 4YW2A 2ZB6A 1MS0A 4XYXA 4D8SA 1IVBA 4X49A 4YZ4A 4D52B 4A0PA 2QWAA 2ZB5A 1DIMA 1MWEA 2HU4A 2WOZA 4XILA 5FNTA 2AH2A 2IARA 2W38A 2Z32A 4X47A 4KS2A 1INXA 4YW5A 1QBIA 2YDPA 2XZJA 2F29A 3II7A 3UC1A 4FPKA 2DG0A 3O9JA 1EURA 1NSDA 3G4HA 3KGGA 2JKBA 4MZEA 1W21A 4HZVA 2H2UA 1MS1A 5D9CA 4NN9A 2ZZKA 4XJRA 3SREA 4FOWA 2IVZA 3GVJA 3ALXA 4XJUA 3HLHA 4WEGA 4ZLRA 4XMBA 4FQ4A 5HUGA 4MWWA 4CPYA 1CQ1A 5GTQA 5CGJA 5GX1A 4I00A 2FPBA 4B7MA 2VPJA 1MS4A 5FZJA 3D11A 2VVZA 4YZ3A 1Z4VA 5NN9A 1U6DX 1ZGKA 4ZGCA 1IVGA 4HZYA 5FNRA 4FP3A 2QWGA 4ASCA 4FPCA 4GZWA 2YA5A 4AGIA 4D52C 2IAPA 4KS5A 3PJQA 4FPFA 2CMLA 4HIZA 3DASA 3K36A 4Q1UA 4DGRA 5H47A 4QN7A 3P5BL 3V64C 1POOA 1F8CA 4QN4A 1W0OA 1IJQA 4GN7A 3A9HA 1NCAN 2VWDA 3NSSA 4MX0A 3TI8A 2VW0A 1NNCA 2SIMA 4MWUA 3K3AA 2C4AA 2ZWAA 4FVKA 1PJXA 2BERA 2VW2A 4WA5A 4NC5A 3B69A 1W20A 4IYGA 3KYAA 2DG1A 1VCJA 5FZNA 1Z4XA 3CL2A 3SILA 2AEPA 4K1JA 2POOA 4GN8A 4GNBA 1MS9A 1E8VA 1L7HA 1L7GA 1IVEA 2XZIA 4B7RA 4WA4A 4B7JA 4HW6A 2A75A 3H71A 1E8TA 2FHRA 2FP9A 1NNBA 2QWJA 2IAQA 1E8UA 2HU0A 1MS3A 4GZOA 2F25A 4R40A 4HHQA 3IAXA 4QNPA 3LI3A 3LI4A 4XHXA 3OPZA 3VNHA 3SOBB 1NCCN 2IAVA 1CRUA 4L7BA 1N1YA 2HT5A 2BF6A 2SILA 4JMLA 4FOVA 4GZPA 3SANA 2W5OA 1INGA 1B9TA 1INFA 2HTYA 4WA3A 3SLIA 4XJAA 4HZWA 2YDTA 4L7CA 3GVLA 2XCYA 1CRZA 2F27A 1A4QA 4YZ2A 4FOQA 1XOEA 3V1SA 2BZDA 4Q6KA 4J9TA 4IQKA 3V65B 1F8BA 4H53A 1NMAN 4H52A 2QWFA 2FLUX 3W09A 3VNGA 3ZGDA 2ZW9A 2GVXA 1RWLA 4MJUA 2VK7A 4XOGA 1N1TA 4GZSA 4M4VA 1SO7A 4GDIA 4HZXA 4ZY3A 2F10A 3FVZA 2IASA 1C9UA 2HTVA 1IVDA 4XHBA 2F28A 1NN2A 1S0IA 1WCSA 3K38A 2YA7A 4IFJA 4KS4A 2IAWA 1A14N 1V3DA 4L7DA 3SOVA 3K37A 4FPJA 4AHAA 5GX4A 2DSOA 2HTUA 1USRA 1N6EA 2XN4A 2RKCA 2F0ZA 3JU4A 4XJWA 2IAUA 2W5NA 5FNQA 3S94A 5D9DA 2QWDA 1C5KA 1H6LA 3WN7A 1IVFA 4FPGA 4IN4A 5EO7A 2HTRA 4XIOA 3A71A 2XZKA 3TI3A 1Z4YA 3T1EA 2IAOA 2P4OA 3WWAA 4GN9A 1NSBA 1V3BA 4XE9A 3TI6A 4GZXA 2VAQA 2VSMA 3AMSA 1USXA 3TC9A 4CH9A 4FPHA 1INHA 5GX2A 3CYEA 3TI4A 1W8OA 4FPYA 1IUCA 3U0SA 1B9VA 1N1VA 2GVVA 5D9BA 3ADEA 4GZTA 4MZAA 1MS5A 3DR2A 1Q7FA 4M4UA 1INVA 4BBWA 3TI5A 2ISMA 5B2DA 1W8NA 4X4AA 4K3YA 4KS1A 1K32A 3TIBA 1WCQA 4D4UA 1Z4ZA 1X2JA 4DG6A 1B9SA 2F13A 2HTWA 4GDJA 4GJTA 1MR5A 1W0PA 4D52A 1V0FA 4HZZA 2OJHA 3H73A 4CPNA 3NN9A 4GB1A 3L6VA 4B7QA 2G8SA 5HX0A 4GZQA 4CPZA 2HTQA 4IFNX 4YW4A 1N6DA 5GX5A 4FPEA 4MWVA 2HQSA 4XIKA 5HUKA 3O9KA 3BYCA 2YA4A 2QWEA 3BEQA 4FOYA 4KS3A 2GHSA 3Q6TA 4WEFA 3S8ZA 3AMRA 1INYA 4M3MA 3G4EA 4FP2A 4MJVA 4QN3A 1NMCA 1SNTA 2F12A 4XJQA 4K1KA 1OFZA 1INWA 1VCUA 4K1HA 1MZ5A 1S0JA 4NCSA 4UOUA 3INBA 1BJIA 2DYHA 2FP8A 2VW1A 2W8BB 3Q6KA 3SRGA 3TIAA 2QWHA 1EUSA 3FW0A 3GVKA 5FNUA 4AGTA 2X9MA 4YZ1A 1V0ZA 4MWRA 4C1YB 1QLGA 1MZ6A 4UF7A 4M4NA 3SALA 1V2IA 2QWBA 3B7EA 1MS8A
chains in the Genus database with same CATH topology
1SUUA 4G3NA 1WP5A 3UC1A 3L6VA 3NO0A 1ZI0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SUU A;  4G3N A;  1WP5 A;  3UC1 A;  3L6V A;  3NO0 A;  1ZI0 A; 
#chains in the Genus database with same CATH topology
 4HHO A;  1V3E A;  2IAX A;  4YW3 A;  3CKZ A;  5FWW A;  4QN6 A;  4QN5 A;  3D12 A;  4FZH A;  2QE8 A;  3E5Z A;  4CHB A;  1NPE A;  4G3N A;  2VSK A;  1EUT A;  4XMA A;  3S2K A;  4MC7 A;  3CL0 A;  1DIL A;  2QWI A;  2F11 A;  3ALW A;  7NN9 A;  3WW9 A;  4FPL A;  5EX7 A;  4K1I A;  5JYY A;  4XJ8 A;  4FJ6 A;  2YA8 A;  3S8V A;  2H2N A;  5F72 C;  2VK6 A;  2F24 A;  1V04 A;  1RWI A;  1EUU A;  3Q6P A;  4AH4 A;  2QWK A;  1NCB N;  2AEQ A;  3TIC A;  4IMB A;  2BAT A;  2HT8 A;  4YW1 A;  1IVC A;  2YA6 A;  2GVW A;  1Z4W A;  5F9T A;  4GEZ A;  1NCD N;  1V3C A;  2HT7 A;  1V0E A;  2GVU A;  4O5S A;  3SOQ A;  4CSD A;  1N7D A;  3HRP A;  3K39 A;  3LI5 A;  2AGS A;  2C4L A;  4JF7 A;  1IUB A;  3H72 A;  3A72 A;  1F8E A;  3H6J A;  1NSC A;  2FPC A;  1N6F A;  1Z50 A;  3A9G A;  4IFL X;  3WDZ A;  1S1D A;  1WP5 A;  4XJZ A;  1CVM A;  4MWJ A;  4FPO B;  5EO8 A;  4MWL A;  5FNS A;  4YY8 A;  2QWC A;  3HLI A;  1F8D A;  4O5T A;  5M1Z A;  1KIT A;  2IAT A;  1SUU A;  2W20 A;  3I1C A;  4CPO A;  2SLI A;  4YZ5 A;  5B2C A;  2W8B A;  1N1S A;  1A4G A;  3NO0 A;  3O4P A;  4MWX A;  1NNA A;  1SLL A;  4CPL A;  4C1Y A;  4CPM A;  4PWZ A;  1ZI0 A;  1W1X A;  5HUN A;  5GX3 A;  4MWQ A;  4N1B A;  4MWY A;  4GNC A;  4XJ9 A;  5HUM A;  6NN9 A;  4X6K A;  2B8H A;  1S18 A;  1SLI A;  1X2R A;  1L7F A;  2VK5 A;  4SLI A;  3ZGC A;  1XOG A;  4GNA A;  1NMB N;  2F26 A;  1E1A A;  2V91 A;  4XMI A;  4B7N A;  4YW2 A;  2ZB6 A;  1MS0 A;  4XYX A;  4D8S A;  1IVB A;  4X49 A;  4YZ4 A;  4D52 B;  4A0P A;  2QWA A;  2ZB5 A;  1DIM A;  1MWE A;  2HU4 A;  2WOZ A;  4XIL A;  5FNT A;  2AH2 A;  2IAR A;  2W38 A;  2Z32 A;  4X47 A;  4KS2 A;  1INX A;  4YW5 A;  1QBI A;  2YDP A;  2XZJ A;  2F29 A;  3II7 A;  3UC1 A;  4FPK A;  2DG0 A;  3O9J A;  1EUR A;  1NSD A;  3G4H A;  3KGG A;  2JKB A;  4MZE A;  1W21 A;  4HZV A;  2H2U A;  1MS1 A;  5D9C A;  4NN9 A;  2ZZK A;  4XJR A;  3SRE A;  4FOW A;  2IVZ A;  3GVJ A;  3ALX A;  4XJU A;  3HLH A;  4WEG A;  4ZLR A;  4XMB A;  4FQ4 A;  5HUG A;  4MWW A;  4CPY A;  1CQ1 A;  5GTQ A;  5CGJ A;  5GX1 A;  4I00 A;  2FPB A;  4B7M A;  2VPJ A;  1MS4 A;  5FZJ A;  3D11 A;  2VVZ A;  4YZ3 A;  1Z4V A;  5NN9 A;  1U6D X;  1ZGK A;  4ZGC A;  1IVG A;  4HZY A;  5FNR A;  4FP3 A;  2QWG A;  4ASC A;  4FPC A;  4GZW A;  2YA5 A;  4AGI A;  4D52 C;  2IAP A;  4KS5 A;  3PJQ A;  4FPF A;  2CML A;  4HIZ A;  3DAS A;  3K36 A;  4Q1U A;  4DGR A;  5H47 A;  4QN7 A;  3P5B L;  3V64 C;  1POO A;  1F8C A;  4QN4 A;  1W0O A;  1IJQ A;  4GN7 A;  3A9H A;  1NCA N;  2VWD A;  3NSS A;  4MX0 A;  3TI8 A;  2VW0 A;  1NNC A;  2SIM A;  4MWU A;  3K3A A;  2C4A A;  2ZWA A;  4FVK A;  1PJX A;  2BER A;  2VW2 A;  4WA5 A;  4NC5 A;  3B69 A;  1W20 A;  4IYG A;  3KYA A;  2DG1 A;  1VCJ A;  5FZN A;  1Z4X A;  3CL2 A;  3SIL A;  2AEP A;  4K1J A;  2POO A;  4GN8 A;  4GNB A;  1MS9 A;  1E8V A;  1L7H A;  1L7G A;  1IVE A;  2XZI A;  4B7R A;  4WA4 A;  4B7J A;  4HW6 A;  2A75 A;  3H71 A;  1E8T A;  2FHR A;  2FP9 A;  1NNB A;  2QWJ A;  2IAQ A;  1E8U A;  2HU0 A;  1MS3 A;  4GZO A;  2F25 A;  4R40 A;  4HHQ A;  3IAX A;  4QNP A;  3LI3 A;  3LI4 A;  4XHX A;  3OPZ A;  3VNH A;  3SOB B;  1NCC N;  2IAV A;  1CRU A;  4L7B A;  1N1Y A;  2HT5 A;  2BF6 A;  2SIL A;  4JML A;  4FOV A;  4GZP A;  3SAN A;  2W5O A;  1ING A;  1B9T A;  1INF A;  2HTY A;  4WA3 A;  3SLI A;  4XJA A;  4HZW A;  2YDT A;  4L7C A;  3GVL A;  2XCY A;  1CRZ A;  2F27 A;  1A4Q A;  4YZ2 A;  4FOQ A;  1XOE A;  3V1S A;  2BZD A;  4Q6K A;  4J9T A;  4IQK A;  3V65 B;  1F8B A;  4H53 A;  1NMA N;  4H52 A;  2QWF A;  2FLU X;  3W09 A;  3VNG A;  3ZGD A;  2ZW9 A;  2GVX A;  1RWL A;  4MJU A;  2VK7 A;  4XOG A;  1N1T A;  4GZS A;  4M4V A;  1SO7 A;  4GDI A;  4HZX A;  4ZY3 A;  2F10 A;  3FVZ A;  2IAS A;  1C9U A;  2HTV A;  1IVD A;  4XHB A;  2F28 A;  1NN2 A;  1S0I A;  1WCS A;  3K38 A;  2YA7 A;  4IFJ A;  4KS4 A;  2IAW A;  1A14 N;  1V3D A;  4L7D A;  3SOV A;  3K37 A;  4FPJ A;  4AHA A;  5GX4 A;  2DSO A;  2HTU A;  1USR A;  1N6E A;  2XN4 A;  2RKC A;  2F0Z A;  3JU4 A;  4XJW A;  2IAU A;  2W5N A;  5FNQ A;  3S94 A;  5D9D A;  2QWD A;  1C5K A;  1H6L A;  3WN7 A;  1IVF A;  4FPG A;  4IN4 A;  5EO7 A;  2HTR A;  4XIO A;  3A71 A;  2XZK A;  3TI3 A;  1Z4Y A;  3T1E A;  2IAO A;  2P4O A;  3WWA A;  4GN9 A;  1NSB A;  1V3B A;  4XE9 A;  3TI6 A;  4GZX A;  2VAQ A;  2VSM A;  3AMS A;  1USX A;  3TC9 A;  4CH9 A;  4FPH A;  1INH A;  5GX2 A;  3CYE A;  3TI4 A;  1W8O A;  4FPY A;  1IUC A;  3U0S A;  1B9V A;  1N1V A;  2GVV A;  5D9B A;  3ADE A;  4GZT A;  4MZA A;  1MS5 A;  3DR2 A;  1Q7F A;  4M4U A;  1INV A;  4BBW A;  3TI5 A;  2ISM A;  5B2D A;  1W8N A;  4X4A A;  4K3Y A;  4KS1 A;  1K32 A;  3TIB A;  1WCQ A;  4D4U A;  1Z4Z A;  1X2J A;  4DG6 A;  1B9S A;  2F13 A;  2HTW A;  4GDJ A;  4GJT A;  1MR5 A;  1W0P A;  4D52 A;  1V0F A;  4HZZ A;  2OJH A;  3H73 A;  4CPN A;  3NN9 A;  4GB1 A;  3L6V A;  4B7Q A;  2G8S A;  5HX0 A;  4GZQ A;  4CPZ A;  2HTQ A;  4IFN X;  4YW4 A;  1N6D A;  5GX5 A;  4FPE A;  4MWV A;  2HQS A;  4XIK A;  5HUK A;  3O9K A;  3BYC A;  2YA4 A;  2QWE A;  3BEQ A;  4FOY A;  4KS3 A;  2GHS A;  3Q6T A;  4WEF A;  3S8Z A;  3AMR A;  1INY A;  4M3M A;  3G4E A;  4FP2 A;  4MJV A;  4QN3 A;  1NMC A;  1SNT A;  2F12 A;  4XJQ A;  4K1K A;  1OFZ A;  1INW A;  1VCU A;  4K1H A;  1MZ5 A;  1S0J A;  4NCS A;  4UOU A;  3INB A;  1BJI A;  2DYH A;  2FP8 A;  2VW1 A;  2W8B B;  3Q6K A;  3SRG A;  3TIA A;  2QWH A;  1EUS A;  3FW0 A;  3GVK A;  5FNU A;  4AGT A;  2X9M A;  4YZ1 A;  1V0Z A;  4MWR A;  4C1Y B;  1QLG A;  1MZ6 A;  4UF7 A;  4M4N A;  3SAL A;  1V2I A;  2QWB A;  3B7E A;  1MS8 A; 
#chains in the Genus database with same CATH homology
 1SUU A;  4G3N A;  1WP5 A;  3UC1 A;  3L6V A;  3NO0 A;  1ZI0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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