3S2KA

Structural basis of wnt signaling inhibition by dickkopf binding to lrp5/6.
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
617
structure length
610
Chain Sequence
PEAFLLFSRRADIRRISLETNNNNVAIPLTGVKEASALDFDVTDNRIYWTDISLKTISRAFMNGSALEHVVEFGLDYPEGMAVDWLGKNLYWADTGTNRIEVSKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGKPKIDRAAMDGSERTTLVPNVGRANGLTIDYAKRRLYWTDLDTNLIESSNMLGLNREVIADDLPHPFGLTQYQDYIYWTDWSRRSIERANKTSGQNRTIIQGHLDYVMDILVFHSSRQSGWNECASSNGHCSHLCLAVPVGGFVCGCPAHYSLNADNRTCSAPTTFLLFSQKSAINRMVIDEQQSPDIILPIHSLRNVRAIDYDPLDKQLYWIDSRQNMIRKAQEDGSQGFTVVVSEIQPYDLSIDIYSRYIYWTCEATNVINVTRLDGRSVGVVLKGEQDRPRAIVVNPEKGYMYFTNLQERSPKIERAALDGTEREVLFFSGLSKPIALALDSRLGKLFWADSDLRRIESSDLSGANRIVLEDSNILQPVGLTVFENWLYWIDKQQQMIEKIDMTGREGRTKVQARIAQLSDIHAVKELNLQEYRQHPCAQDNGGCSHICLVKGDGTTRCSCPMHLVLLQDELSCGEP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Low-density lipoprotein receptor-related protein 6
total genus 143
structure length 610
sequence length 617
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00058 Ldl_recept_b Low-density lipoprotein receptor repeat class B
A PF14670 FXa_inhibition Coagulation Factor Xa inhibitory site
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.30 Mainly Beta 6 Propeller Neuraminidase TolB, C-terminal domain 3s2kA02
2.120.10.30 Mainly Beta 6 Propeller Neuraminidase TolB, C-terminal domain 3s2kA01
4HHQA 4O5SA 2W8BB 3I1CA 1CRZA 2IATA 2GVVA 5FWWA 2GVWA 4ZLRA 5D9CA 2IAWA 2FPCA 3IAXA 5D9DA 1CVMA 3BYCA 3SOBB 3SOQA 2GVUA 3LI4A 2FP8A 1Q7FA 3Q6PA 1QLGA 3P5BL 2IAVA 2FPBA 3SOVA 3LI5A 3O4PA 3S2KA 2IVZA 2OJHA 4GNAA 1POOA 2DG0A 2VAQA 3SRGA 3U0SA 3DASA 3WWAA 1N7DA 4GN7A 3V65B 4R40A 2DSOA 3V64C 5GX1A 3A9GA 3DR2A 2HQSA 2QE8A 3E5ZA 4DG6A 4GNCA 4IMBA 3S8VA 3FVZA 3TC9A 2G8SA 1QBIA 5EX7A 3S94A 2IAPA 3LI3A 2IAQA 1CQ1A 3SREA 5GX2A 4A0PA 2IAUA 3G4EA 2POOA 5GTQA 2IARA 2ISMA 3A9HA 3S8ZA 4O5TA 2V91A 3AMSA 2IAXA 4Q1UA 2P4OA 5GX4A 1PJXA 2IAOA 4GNBA 4JMLA 4IYGA 1NPEA 1RWIA 2W8BA 1H6LA 1CRUA 2DG1A 1C9UA 4GN8A 1C5KA 4PWZA 4GN9A 3AMRA 1E1AA 3KYAA 3Q6TA 2IASA 4HW6A 2FP9A 3FW0A 3WW9A 3HLIA 3Q6KA 3KGGA 1RWLA 5GX3A 2GVXA 3HRPA 5GX5A 5D9BA 3G4HA 2GHSA 3V1SA 1IJQA 4HHOA 3HLHA 1V04A
chains in the Genus database with same CATH superfamily
4K1JA 1INFA 1INHA 1MZ5A 1IUCA 4NCSA 1XOGA 5CGJA 2VSMA 5FWWA 3TIBA 5NN9A 4DGRA 2W20A 3IAXA 2QWJA 1USXA 4NN9A 1CVMA 3SOQA 2ZZKA 4FOQA 4YZ1A 4FVKA 4KS3A 4GZPA 2FLUX 4FJ6A 2VW2A 1ZI0A 4AH4A 3PJQA 4FPEA 5FNRA 4CPYA 5EO8A 1K32A 4IQKA 3P5BL 1INWA 3LI5A 1S1DA 4YZ5A 4ZY3A 1W0PA 4GNAA 1OFZA 1MS1A 3U0SA 4MWWA 1SO7A 1W0OA 5B2DA 1IUBA 4MJUA 4R40A 4CHBA 4KS2A 4X47A 3INBA 4HZYA 4DG6A 1Z4VA 2F10A 4K3YA 2YA4A 4H52A 2F28A 2CMLA 3ADEA 3TI6A 3K38A 3S94A 3LI3A 2IAQA 1B9VA 1CQ1A 1SNTA 2IAUA 5FNTA 3SILA 5F72C 2XN4A 5GTQA 1L7HA 4FOVA 4XILA 4CH9A 1NSBA 3AMSA 4CPMA 5F9TA 4Q1UA 1PJXA 4AHAA 1B9TA 5FNQA 3CYEA 1EUUA 1VCUA 1W8OA 1Z4YA 1IVBA 2W5NA 3CL2A 1X2JA 1F8DA 2VK7A 1N6FA 2F26A 2A75A 3H72A 1C9UA 4GN8A 2F29A 2HU0A 1XOEA 2W38A 2YA6A 4HZWA 1E8UA 4XMIA 2HT8A 3TI3A 4XJWA 2XCYA 4XIOA 4CPZA 1W20A 3Q6TA 4XE9A 1Z50A 1F8BA 3TI5A 4XJUA 1DILA 1Z4ZA 4D4UA 4D8SA 3B69A 3GVJA 2GVXA 1N1TA 1IVCA 4FP2A 3G4HA 1INXA 1SLLA 2HT5A 3VNGA 3H73A 2VPJA 1CRZA 2IATA 4FPCA 4IFNX 4XJ8A 1N6DA 4M3MA 5FNUA 1W8NA 5D9CA 4QN7A 4M4NA 1ZGKA 4YW4A 1NSCA 4UF7A 2GVUA 2BERA 2VK6A 1F8EA 4AGIA 1QLGA 3OPZA 4QN6A 5JYYA 3K37A 3SRGA 1POOA 2VAQA 1INYA 1MS5A 4FPFA 1N1YA 1N7DA 2SLIA 4GN7A 3V64C 4D52A 4YZ4A 3K39A 3WN7A 4M4VA 2YDPA 1V0ZA 5FZJA 4IFLX 2G8SA 1V3DA 2XZJA 2XZIA 3SREA 2B8HA 2HTQA 4SLIA 2F27A 4XOGA 2QWAA 2IARA 2ISMA 1L7GA 4J9TA 1NMCA 2HTYA 2QWIA 2V91A 1VCJA 1INVA 4XIKA 4D52C 2F0ZA 5GX4A 4YW5A 5H47A 1V3BA 1NMAN 2QWKA 4X6KA 1A14N 1E8TA 4KS4A 3ALXA 4MWLA 4FPHA 2YA7A 1MS0A 1A4GA 1N1VA 1B9SA 1MWEA 2HT7A 2DG1A 5HUKA 4GZOA 4QNPA 2C4LA 3GVKA 4FQ4A 4L7CA 4GZSA 1Z4WA 2QWBA 4HW6A 2QWEA 3K36A 1MR5A 3WW9A 4MWYA 3Q6KA 4D52B 4GDJA 4WA3A 4GZXA 2VW0A 5GX3A 4FZHA 5EO7A 4MX0A 1W21A 3V1SA 1IJQA 2YDTA 4X4AA 4HHQA 4H53A 4O5SA 1IVEA 3I1CA 2AEPA 4MWXA 3TICA 4B7NA 1WCQA 4N1BA 3ZGCA 1N6EA 2GVWA 4ZLRA 4YZ3A 3SALA 2IAWA 4CPOA 2FPCA 1SLIA 1V0EA 4GJTA 2W5OA 4GDIA 5D9DA 3SOBB 4GEZA 1EUTA 1DIMA 2FP8A 3LI4A 1IVDA 4KS5A 4YW3A 3BEQA 4YY8A 1W1XA 2VW1A 3JU4A 4FOWA 4IFJA 4L7DA 4MWUA 2IAVA 4IN4A 4XMAA 3SOVA 2F24A 3O4PA 2VWDA 4FPGA 3S2KA 2VVZA 2DG0A 2RKCA 1NCBN 3K3AA 2AEQA 4GZWA 5FZNA 4MC7A 4CPNA 5GX1A 3T1EA 4C1YA 2HQSA 2QE8A 1L7FA 4XJ9A 1KITA 3SANA 4ASCA 2SILA 3H71A 3TI4A 3FVZA 3TC9A 1V3CA 1F8CA 2ZB5A 3O9KA 4B7QA 4K1IA 3L6VA 4HZZA 4GB1A 5M1ZA 7NN9A 4WEFA 3A9HA 4MZEA 2QWCA 3S8ZA 5HUGA 3O9JA 1INGA 4XMBA 4MWJA 4O5TA 1WCSA 4YZ2A 2F13A 2IAXA 2F25A 2ZWAA 4HIZA 4M4UA 4FPKA 4FP3A 2IAOA 2F12A 5FNSA 4MWQA 1MS4A 2DYHA 2BATA 4IYGA 1RWIA 1NNCA 1H6LA 4K1HA 3B7EA 1CRUA 1E8VA 1IVGA 4BBWA 5B2CA 4PWZA 4YW2A 2C4AA 4GN9A 1A4QA 1V3EA 1NSDA 3AMRA 2HTWA 2IASA 3FW0A 4FOYA 1MS9A 3KGGA 2VK5A 4K1KA 1RWLA 4C1YB 4MWRA 5D9BA 4GZQA 2GHSA 2JKBA 1SUUA 2QWGA 3HLHA 2ZW9A 4HHOA 3NSSA 3CL0A 4L7BA 2YA8A 4B7RA 2W8BB 1N1SA 3NO0A 2SIMA 2WOZA 1EUSA 2GVVA 4HZVA 1EURA 4CSDA 2QWHA 4UOUA 4WEGA 5HX0A 2HTRA 2HTUA 4I00A 3H6JA 4Q6KA 3BYCA 2YA5A 4XJAA 1NMBN 3UC1A 1Q7FA 3Q6PA 4XHBA 1BJIA 1S0IA 4GZTA 4KS1A 4B7JA 3WDZA 4MWVA 4WA5A 3GVLA 2FHRA 1V2IA 4HZXA 2FPBA 4QN5A 3A72A 5HUMA 2BF6A 1NCCN 1NNBA 2IVZA 3W09A 2OJHA 3TI8A 2H2NA 3DASA 2H2UA 3WWAA 6NN9A 3V65B 1MS8A 2Z32A 4XJRA 2DSOA 3D12A 4FPOB 3ALWA 3A9GA 3SLIA 1NCAN 3DR2A 3E5ZA 2QWDA 2XZKA 1MS3A 4GNCA 4IMBA 4MJVA 4AGTA 3S8VA 3TIAA 2QWFA 1S0JA 4YW1A 4CPLA 2BZDA 4XYXA 1QBIA 1NCDN 5EX7A 4XHXA 4NC5A 4QN4A 4X49A 2IAPA 4ZGCA 4WA4A 5GX2A 1USRA 4A0PA 3G4EA 2POOA 1MZ6A 4FPLA 3II7A 2P4OA 1IVFA 1NN2A 5HUNA 3NN9A 4FPYA 4GNBA 4JMLA 3ZGDA 1V0FA 4B7MA 4QN3A 1NPEA 4MZAA 1S18A 2VSKA 2W8BA 4JF7A 2HU4A 2X9MA 1C5KA 2HTVA 4FPJA 3VNHA 3CKZA 1X2RA 2ZB6A 1E1AA 1Z4XA 1U6DX 3KYAA 1NNAA 3D11A 2FP9A 4XJQA 4G3NA 2AH2A 3HLIA 4XJZA 2F11A 3HRPA 5GX5A 1WP5A 3A71A 1V04A 2AGSA
chains in the Genus database with same CATH topology
4HHQA 4O5SA 2W8BB 3I1CA 1CRZA 2IATA 2GVVA 5FWWA 2GVWA 4ZLRA 5D9CA 2IAWA 2FPCA 3IAXA 5D9DA 1CVMA 3BYCA 3SOBB 3SOQA 2GVUA 3LI4A 2FP8A 1Q7FA 3Q6PA 1QLGA 3P5BL 2IAVA 2FPBA 3SOVA 3LI5A 3O4PA 3S2KA 2IVZA 2OJHA 4GNAA 1POOA 2DG0A 2VAQA 3SRGA 3U0SA 3DASA 3WWAA 1N7DA 4GN7A 3V65B 4R40A 2DSOA 3V64C 5GX1A 3A9GA 3DR2A 2HQSA 2QE8A 3E5ZA 4DG6A 4GNCA 4IMBA 3S8VA 3FVZA 3TC9A 2G8SA 1QBIA 5EX7A 3S94A 2IAPA 3LI3A 2IAQA 1CQ1A 3SREA 5GX2A 4A0PA 2IAUA 3G4EA 2POOA 5GTQA 2IARA 2ISMA 3A9HA 3S8ZA 4O5TA 2V91A 3AMSA 2IAXA 4Q1UA 2P4OA 5GX4A 1PJXA 2IAOA 4GNBA 4JMLA 4IYGA 1NPEA 1RWIA 2W8BA 1H6LA 1CRUA 2DG1A 1C9UA 4GN8A 1C5KA 4PWZA 4GN9A 3AMRA 1E1AA 3KYAA 3Q6TA 2IASA 4HW6A 2FP9A 3FW0A 3WW9A 3HLIA 3Q6KA 3KGGA 1RWLA 5GX3A 2GVXA 3HRPA 5GX5A 5D9BA 3G4HA 2GHSA 3V1SA 1IJQA 4HHOA 3HLHA 1V04A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HHQ A;  4O5S A;  2W8B B;  3I1C A;  1CRZ A;  2IAT A;  2GVV A;  5FWW A;  2GVW A;  4ZLR A;  5D9C A;  2IAW A;  2FPC A;  3IAX A;  5D9D A;  1CVM A;  3BYC A;  3SOB B;  3SOQ A;  2GVU A;  3LI4 A;  2FP8 A;  1Q7F A;  3Q6P A;  1QLG A;  3P5B L;  2IAV A;  2FPB A;  3SOV A;  3LI5 A;  3O4P A;  3S2K A;  2IVZ A;  2OJH A;  4GNA A;  1POO A;  2DG0 A;  2VAQ A;  3SRG A;  3U0S A;  3DAS A;  3WWA A;  1N7D A;  4GN7 A;  3V65 B;  4R40 A;  2DSO A;  3V64 C;  5GX1 A;  3A9G A;  3DR2 A;  2HQS A;  2QE8 A;  3E5Z A;  4DG6 A;  4GNC A;  4IMB A;  3S8V A;  3FVZ A;  3TC9 A;  2G8S A;  1QBI A;  5EX7 A;  3S94 A;  2IAP A;  3LI3 A;  2IAQ A;  1CQ1 A;  3SRE A;  5GX2 A;  4A0P A;  2IAU A;  3G4E A;  2POO A;  5GTQ A;  2IAR A;  2ISM A;  3A9H A;  3S8Z A;  4O5T A;  2V91 A;  3AMS A;  2IAX A;  4Q1U A;  2P4O A;  5GX4 A;  1PJX A;  2IAO A;  4GNB A;  4JML A;  4IYG A;  1NPE A;  1RWI A;  2W8B A;  1H6L A;  1CRU A;  2DG1 A;  1C9U A;  4GN8 A;  1C5K A;  4PWZ A;  4GN9 A;  3AMR A;  1E1A A;  3KYA A;  3Q6T A;  2IAS A;  4HW6 A;  2FP9 A;  3FW0 A;  3WW9 A;  3HLI A;  3Q6K A;  3KGG A;  1RWL A;  5GX3 A;  2GVX A;  3HRP A;  5GX5 A;  5D9B A;  3G4H A;  2GHS A;  3V1S A;  1IJQ A;  4HHO A;  3HLH A;  1V04 A; 
#chains in the Genus database with same CATH topology
 4K1J A;  1INF A;  1INH A;  1MZ5 A;  1IUC A;  4NCS A;  1XOG A;  5CGJ A;  2VSM A;  5FWW A;  3TIB A;  5NN9 A;  4DGR A;  2W20 A;  3IAX A;  2QWJ A;  1USX A;  4NN9 A;  1CVM A;  3SOQ A;  2ZZK A;  4FOQ A;  4YZ1 A;  4FVK A;  4KS3 A;  4GZP A;  2FLU X;  4FJ6 A;  2VW2 A;  1ZI0 A;  4AH4 A;  3PJQ A;  4FPE A;  5FNR A;  4CPY A;  5EO8 A;  1K32 A;  4IQK A;  3P5B L;  1INW A;  3LI5 A;  1S1D A;  4YZ5 A;  4ZY3 A;  1W0P A;  4GNA A;  1OFZ A;  1MS1 A;  3U0S A;  4MWW A;  1SO7 A;  1W0O A;  5B2D A;  1IUB A;  4MJU A;  4R40 A;  4CHB A;  4KS2 A;  4X47 A;  3INB A;  4HZY A;  4DG6 A;  1Z4V A;  2F10 A;  4K3Y A;  2YA4 A;  4H52 A;  2F28 A;  2CML A;  3ADE A;  3TI6 A;  3K38 A;  3S94 A;  3LI3 A;  2IAQ A;  1B9V A;  1CQ1 A;  1SNT A;  2IAU A;  5FNT A;  3SIL A;  5F72 C;  2XN4 A;  5GTQ A;  1L7H A;  4FOV A;  4XIL A;  4CH9 A;  1NSB A;  3AMS A;  4CPM A;  5F9T A;  4Q1U A;  1PJX A;  4AHA A;  1B9T A;  5FNQ A;  3CYE A;  1EUU A;  1VCU A;  1W8O A;  1Z4Y A;  1IVB A;  2W5N A;  3CL2 A;  1X2J A;  1F8D A;  2VK7 A;  1N6F A;  2F26 A;  2A75 A;  3H72 A;  1C9U A;  4GN8 A;  2F29 A;  2HU0 A;  1XOE A;  2W38 A;  2YA6 A;  4HZW A;  1E8U A;  4XMI A;  2HT8 A;  3TI3 A;  4XJW A;  2XCY A;  4XIO A;  4CPZ A;  1W20 A;  3Q6T A;  4XE9 A;  1Z50 A;  1F8B A;  3TI5 A;  4XJU A;  1DIL A;  1Z4Z A;  4D4U A;  4D8S A;  3B69 A;  3GVJ A;  2GVX A;  1N1T A;  1IVC A;  4FP2 A;  3G4H A;  1INX A;  1SLL A;  2HT5 A;  3VNG A;  3H73 A;  2VPJ A;  1CRZ A;  2IAT A;  4FPC A;  4IFN X;  4XJ8 A;  1N6D A;  4M3M A;  5FNU A;  1W8N A;  5D9C A;  4QN7 A;  4M4N A;  1ZGK A;  4YW4 A;  1NSC A;  4UF7 A;  2GVU A;  2BER A;  2VK6 A;  1F8E A;  4AGI A;  1QLG A;  3OPZ A;  4QN6 A;  5JYY A;  3K37 A;  3SRG A;  1POO A;  2VAQ A;  1INY A;  1MS5 A;  4FPF A;  1N1Y A;  1N7D A;  2SLI A;  4GN7 A;  3V64 C;  4D52 A;  4YZ4 A;  3K39 A;  3WN7 A;  4M4V A;  2YDP A;  1V0Z A;  5FZJ A;  4IFL X;  2G8S A;  1V3D A;  2XZJ A;  2XZI A;  3SRE A;  2B8H A;  2HTQ A;  4SLI A;  2F27 A;  4XOG A;  2QWA A;  2IAR A;  2ISM A;  1L7G A;  4J9T A;  1NMC A;  2HTY A;  2QWI A;  2V91 A;  1VCJ A;  1INV A;  4XIK A;  4D52 C;  2F0Z A;  5GX4 A;  4YW5 A;  5H47 A;  1V3B A;  1NMA N;  2QWK A;  4X6K A;  1A14 N;  1E8T A;  4KS4 A;  3ALX A;  4MWL A;  4FPH A;  2YA7 A;  1MS0 A;  1A4G A;  1N1V A;  1B9S A;  1MWE A;  2HT7 A;  2DG1 A;  5HUK A;  4GZO A;  4QNP A;  2C4L A;  3GVK A;  4FQ4 A;  4L7C A;  4GZS A;  1Z4W A;  2QWB A;  4HW6 A;  2QWE A;  3K36 A;  1MR5 A;  3WW9 A;  4MWY A;  3Q6K A;  4D52 B;  4GDJ A;  4WA3 A;  4GZX A;  2VW0 A;  5GX3 A;  4FZH A;  5EO7 A;  4MX0 A;  1W21 A;  3V1S A;  1IJQ A;  2YDT A;  4X4A A;  4HHQ A;  4H53 A;  4O5S A;  1IVE A;  3I1C A;  2AEP A;  4MWX A;  3TIC A;  4B7N A;  1WCQ A;  4N1B A;  3ZGC A;  1N6E A;  2GVW A;  4ZLR A;  4YZ3 A;  3SAL A;  2IAW A;  4CPO A;  2FPC A;  1SLI A;  1V0E A;  4GJT A;  2W5O A;  4GDI A;  5D9D A;  3SOB B;  4GEZ A;  1EUT A;  1DIM A;  2FP8 A;  3LI4 A;  1IVD A;  4KS5 A;  4YW3 A;  3BEQ A;  4YY8 A;  1W1X A;  2VW1 A;  3JU4 A;  4FOW A;  4IFJ A;  4L7D A;  4MWU A;  2IAV A;  4IN4 A;  4XMA A;  3SOV A;  2F24 A;  3O4P A;  2VWD A;  4FPG A;  3S2K A;  2VVZ A;  2DG0 A;  2RKC A;  1NCB N;  3K3A A;  2AEQ A;  4GZW A;  5FZN A;  4MC7 A;  4CPN A;  5GX1 A;  3T1E A;  4C1Y A;  2HQS A;  2QE8 A;  1L7F A;  4XJ9 A;  1KIT A;  3SAN A;  4ASC A;  2SIL A;  3H71 A;  3TI4 A;  3FVZ A;  3TC9 A;  1V3C A;  1F8C A;  2ZB5 A;  3O9K A;  4B7Q A;  4K1I A;  3L6V A;  4HZZ A;  4GB1 A;  5M1Z A;  7NN9 A;  4WEF A;  3A9H A;  4MZE A;  2QWC A;  3S8Z A;  5HUG A;  3O9J A;  1ING A;  4XMB A;  4MWJ A;  4O5T A;  1WCS A;  4YZ2 A;  2F13 A;  2IAX A;  2F25 A;  2ZWA A;  4HIZ A;  4M4U A;  4FPK A;  4FP3 A;  2IAO A;  2F12 A;  5FNS A;  4MWQ A;  1MS4 A;  2DYH A;  2BAT A;  4IYG A;  1RWI A;  1NNC A;  1H6L A;  4K1H A;  3B7E A;  1CRU A;  1E8V A;  1IVG A;  4BBW A;  5B2C A;  4PWZ A;  4YW2 A;  2C4A A;  4GN9 A;  1A4Q A;  1V3E A;  1NSD A;  3AMR A;  2HTW A;  2IAS A;  3FW0 A;  4FOY A;  1MS9 A;  3KGG A;  2VK5 A;  4K1K A;  1RWL A;  4C1Y B;  4MWR A;  5D9B A;  4GZQ A;  2GHS A;  2JKB A;  1SUU A;  2QWG A;  3HLH A;  2ZW9 A;  4HHO A;  3NSS A;  3CL0 A;  4L7B A;  2YA8 A;  4B7R A;  2W8B B;  1N1S A;  3NO0 A;  2SIM A;  2WOZ A;  1EUS A;  2GVV A;  4HZV A;  1EUR A;  4CSD A;  2QWH A;  4UOU A;  4WEG A;  5HX0 A;  2HTR A;  2HTU A;  4I00 A;  3H6J A;  4Q6K A;  3BYC A;  2YA5 A;  4XJA A;  1NMB N;  3UC1 A;  1Q7F A;  3Q6P A;  4XHB A;  1BJI A;  1S0I A;  4GZT A;  4KS1 A;  4B7J A;  3WDZ A;  4MWV A;  4WA5 A;  3GVL A;  2FHR A;  1V2I A;  4HZX A;  2FPB A;  4QN5 A;  3A72 A;  5HUM A;  2BF6 A;  1NCC N;  1NNB A;  2IVZ A;  3W09 A;  2OJH A;  3TI8 A;  2H2N A;  3DAS A;  2H2U A;  3WWA A;  6NN9 A;  3V65 B;  1MS8 A;  2Z32 A;  4XJR A;  2DSO A;  3D12 A;  4FPO B;  3ALW A;  3A9G A;  3SLI A;  1NCA N;  3DR2 A;  3E5Z A;  2QWD A;  2XZK A;  1MS3 A;  4GNC A;  4IMB A;  4MJV A;  4AGT A;  3S8V A;  3TIA A;  2QWF A;  1S0J A;  4YW1 A;  4CPL A;  2BZD A;  4XYX A;  1QBI A;  1NCD N;  5EX7 A;  4XHX A;  4NC5 A;  4QN4 A;  4X49 A;  2IAP A;  4ZGC A;  4WA4 A;  5GX2 A;  1USR A;  4A0P A;  3G4E A;  2POO A;  1MZ6 A;  4FPL A;  3II7 A;  2P4O A;  1IVF A;  1NN2 A;  5HUN A;  3NN9 A;  4FPY A;  4GNB A;  4JML A;  3ZGD A;  1V0F A;  4B7M A;  4QN3 A;  1NPE A;  4MZA A;  1S18 A;  2VSK A;  2W8B A;  4JF7 A;  2HU4 A;  2X9M A;  1C5K A;  2HTV A;  4FPJ A;  3VNH A;  3CKZ A;  1X2R A;  2ZB6 A;  1E1A A;  1Z4X A;  1U6D X;  3KYA A;  1NNA A;  3D11 A;  2FP9 A;  4XJQ A;  4G3N A;  2AH2 A;  3HLI A;  4XJZ A;  2F11 A;  3HRP A;  5GX5 A;  1WP5 A;  3A71 A;  1V04 A;  2AGS A; 
#chains in the Genus database with same CATH homology
 4HHQ A;  4O5S A;  2W8B B;  3I1C A;  1CRZ A;  2IAT A;  2GVV A;  5FWW A;  2GVW A;  4ZLR A;  5D9C A;  2IAW A;  2FPC A;  3IAX A;  5D9D A;  1CVM A;  3BYC A;  3SOB B;  3SOQ A;  2GVU A;  3LI4 A;  2FP8 A;  1Q7F A;  3Q6P A;  1QLG A;  3P5B L;  2IAV A;  2FPB A;  3SOV A;  3LI5 A;  3O4P A;  3S2K A;  2IVZ A;  2OJH A;  4GNA A;  1POO A;  2DG0 A;  2VAQ A;  3SRG A;  3U0S A;  3DAS A;  3WWA A;  1N7D A;  4GN7 A;  3V65 B;  4R40 A;  2DSO A;  3V64 C;  5GX1 A;  3A9G A;  3DR2 A;  2HQS A;  2QE8 A;  3E5Z A;  4DG6 A;  4GNC A;  4IMB A;  3S8V A;  3FVZ A;  3TC9 A;  2G8S A;  1QBI A;  5EX7 A;  3S94 A;  2IAP A;  3LI3 A;  2IAQ A;  1CQ1 A;  3SRE A;  5GX2 A;  4A0P A;  2IAU A;  3G4E A;  2POO A;  5GTQ A;  2IAR A;  2ISM A;  3A9H A;  3S8Z A;  4O5T A;  2V91 A;  3AMS A;  2IAX A;  4Q1U A;  2P4O A;  5GX4 A;  1PJX A;  2IAO A;  4GNB A;  4JML A;  4IYG A;  1NPE A;  1RWI A;  2W8B A;  1H6L A;  1CRU A;  2DG1 A;  1C9U A;  4GN8 A;  1C5K A;  4PWZ A;  4GN9 A;  3AMR A;  1E1A A;  3KYA A;  3Q6T A;  2IAS A;  4HW6 A;  2FP9 A;  3FW0 A;  3WW9 A;  3HLI A;  3Q6K A;  3KGG A;  1RWL A;  5GX3 A;  2GVX A;  3HRP A;  5GX5 A;  5D9B A;  3G4H A;  2GHS A;  3V1S A;  1IJQ A;  4HHO A;  3HLH A;  1V04 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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