3VNGA

Crystal structure of keap1 in complex with synthetic small molecular based on a co-crystallization
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
288
structure length
288
Chain Sequence
PKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Keap1 in Complex with Synthetic Small Molecular based on a co-crystallization
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Kelch-like ECH-associated protein 1
total genus 63
structure length 288
sequence length 288
ec nomenclature
pdb deposition date 2012-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 3vngA00
4L7DA 2ZWAA 4IFNX 4L7BA 2XN4A 3WN7A 4XMBA 1X2RA 5F72C 4YY8A 4CHBA 4IN4A 4IQKA 3ADEA 2DYHA 3ZGDA 5FNSA 3VNGA 1ZGKA 5FNTA 4IFLX 3II7A 4N1BA 5FNUA 3VNHA 2ZZKA 3WDZA 2FLUX 4ZGCA 4ASCA 5FNRA 5FZJA 1U6DX 5FZNA 4ZY3A 2VPJA 4L7CA 5CGJA 4IFJA 2Z32A 5FNQA 1X2JA 2WOZA 2ZW9A 3ZGCA 4CH9A
chains in the Genus database with same CATH superfamily
4G3NA 4XJWA 1S0JA 2HTRA 4HZXA 4AH4A 2IATA 1B9SA 4ZLRA 4K1HA 2IAQA 2W5OA 4WEFA 1W21A 1USXA 2IASA 2QWIA 1EUSA 4ZGCA 2W5NA 2HT8A 1NNCA 3TI4A 4FZHA 3K3AA 1S18A 2QWBA 4YZ2A 2QWGA 4FPCA 3NO0A 3O4PA 3SOBB 4AHAA 4HZWA 5FNQA 4BBWA 3V64C 3ALXA 4FOWA 2VPJA 2ZW9A 3K36A 2A75A 4CPNA 4MWUA 4B7JA 1W8NA 3P5BL 4O5SA 2W20A 3T1EA 5F9TA 4Q6KA 2SILA 3NN9A 2AEPA 2XCYA 3O9KA 1NCBN 1MS9A 4MZAA 1CVMA 1MZ5A 1Q7FA 1IVDA 2FP8A 4FPJA 2XZIA 2VSMA 2HTVA 4GDIA 4H52A 2ZWAA 4KS4A 2AH2A 4XJUA 3S8VA 2GVVA 4FPKA 5JYYA 4XOGA 1E1AA 4GN7A 1F8BA 3AMSA 1RWIA 3IAXA 4IFLX 4YW2A 5HUMA 3GVJA 4MWVA 4XHXA 5GX2A 2CMLA 4GEZA 2W8BA 3OPZA 1BJIA 1S0IA 1IVFA 4SLIA 3B7EA 4M3MA 4YZ1A 2Z32A 3H73A 1V0EA 1WCQA 2HT7A 4X4AA 2V91A 2SLIA 4MWQA 1Z4YA 3ALWA 1C9UA 2HTWA 4CHBA 3A72A 2YDTA 1CRZA 4R40A 1QLGA 4FOQA 1CQ1A 4UOUA 5FNRA 1INVA 4M4UA 4FPOB 4KS1A 5GX4A 1W0OA 5NN9A 1DIMA 2IVZA 4FJ6A 5EO7A 4WEGA 3ZGCA 4GNBA 1NCDN 2FPBA 4DG6A 4FPYA 3H71A 3WW9A 1X2RA 4MWLA 2VSKA 4XHBA 2YA5A 2BF6A 1B9TA 2BATA 4GDJA 1N1TA 1XOGA 1A4GA 2YA7A 4H53A 4XJ8A 4D4UA 3L6VA 4MWXA 2QWHA 2VK7A 4YZ3A 1E8VA 4C1YA 5GTQA 1KITA 2F10A 2F12A 2G8SA 1MS5A 2W38A 1OFZA 2AGSA 4MJUA 4CPOA 4MWRA 4GZXA 4XMIA 4XMBA 3NSSA 3SALA 2OJHA 2GVUA 5HUNA 3JU4A 2C4LA 1L7FA 1V3BA 1A14N 2HTUA 3SOQA 3HLIA 2FHRA 3WDZA 4UF7A 4ASCA 1VCJA 4GN8A 1XOEA 2FP9A 2IAWA 2YA6A 4M4NA 1NCCN 4D52B 2F27A 1INXA 1SLLA 3H6JA 1QBIA 1MS3A 4XIOA 2B8HA 1INFA 2DG1A 3V1SA 4HHOA 1V04A 2IAUA 1INYA 1MWEA 1B9VA 3BEQA 1W8OA 4YW4A 3SREA 2IAXA 4X47A 4XILA 4NC5A 1WP5A 3W09A 4O5TA 1SLIA 3CL2A 3CYEA 5M1ZA 3TIBA 4QN3A 3TI6A 5D9DA 1NNAA 2QWEA 4HIZA 4M4VA 3S2KA 3TI8A 4YY8A 4WA4A 1W0PA 4FPHA 3FW0A 4HZZA 4K1JA 2HT5A 3TICA 4FQ4A 2ZB6A 4CPYA 1N1SA 4MWYA 2HTQA 4AGIA 4MJVA 4GJTA 4MWWA 1V0ZA 3D11A 3S94A 3V65B 1INGA 3SILA 2FPCA 2IAOA 3WWAA 3D12A 4GZQA 3DR2A 1IVCA 4GNAA 2QE8A 4KS3A 4YZ5A 3G4HA 1SUUA 3HRPA 2QWFA 1H6LA 4FOVA 1NMCA 4A0PA 3SRGA 4GB1A 5H47A 3AMRA 4GN9A 4KS2A 5D9CA 2FLUX 4IYGA 2XZKA 1N6DA 1MS4A 5HX0A 4D52C 2DG0A 4JMLA 1CRUA 4AGTA 4CSDA 2QWDA 4X49A 5HUKA 1F8DA 4L7DA 1MZ6A 3WN7A 1NMBN 1L7GA 1V2IA 1Z50A 3FVZA 1IVEA 2DYHA 4WA5A 4CPMA 4HZYA 2YDPA 2VW0A 1DILA 2F29A 1Z4ZA 2YA8A 4GZOA 1E8TA 4I00A 4JF7A 1INWA 4GZTA 2H2NA 1U6DX 1SNTA 3GVKA 5FWWA 2RKCA 1E8UA 5FZNA 3GVLA 4D8SA 1VCUA 5CGJA 4FPLA 3KYAA 3E5ZA 1IJQA 2VAQA 3Q6PA 1A4QA 3TIAA 2HU4A 2QWKA 2XZJA 2F25A 3TI5A 2HTYA 1MR5A 5D9BA 4IQKA 2W8BB 5FNSA 1IUCA 2HU0A 5FNUA 4HW6A 3VNHA 3CL0A 3O9JA 4MX0A 4FPGA 1V3EA 5EO8A 4XJAA 2BZDA 2VK5A 1RWLA 2F11A 2IAPA 4CPZA 4QNPA 4WA3A 3U0SA 4QN6A 1F8CA 1S1DA 3PJQA 3K38A 4QN7A 1N1VA 3ADEA 4FP2A 1EURA 2X9MA 1PJXA 4GNCA 4QN4A 1IVGA 2QWJA 4K1IA 4FPEA 4N1BA 3INBA 1EUUA 2ZZKA 4GZPA 3K37A 1MS1A 4XJ9A 1Z4XA 4B7NA 1N7DA 2ISMA 1SO7A 4YZ4A 4XJRA 3UC1A 2F24A 1N6FA 4CPLA 4KS5A 1W20A 2VW1A 1NSCA 2F13A 1N6EA 1IVBA 4NCSA 1NCAN 1USRA 3LI5A 2GVXA 4FOYA 4XMAA 3VNGA 5FNTA 3LI3A 3II7A 4YW5A 4Q1UA 4C1YB 1NPEA 1K32A 4XIKA 4XYXA 2F0ZA 1NN2A 4ZY3A 4B7MA 4IFJA 4FP3A 4FPFA 3G4EA 5B2CA 2IAVA 4PWZA 3Q6TA 3I1CA 3Q6KA 4FVKA 4IFNX 4L7BA 5GX5A 3SOVA 1INHA 1F8EA 6NN9A 3KGGA 4XE9A 3K39A 1NSDA 3B69A 4IN4A 3ZGDA 4IMBA 1IUBA 5GX1A 1N1YA 1NSBA 4MWJA 2GVWA 4QN5A 4HHQA 5B2DA 2DSOA 2F28A 3A9GA 1MS0A 4GZWA 2POOA 2VK6A 4GZSA 5GX3A 2SIMA 1EUTA 1X2JA 2JKBA 4B7RA 2WOZA 3LI4A 4DGRA 4K1KA 1V0FA 2C4AA 4YW1A 4D52A 1V3DA 2GHSA 1ZGKA 4MZEA 3DASA 1NNBA 3S8ZA 3BYCA 4XJQA 2F26A 1WCSA 1ZI0A 3SANA 4K3YA 3SLIA 5FZJA 2P4OA 2HQSA 2QWAA 4L7CA 2VVZA 1Z4WA 7NN9A 3CKZA 1Z4VA 3A71A 3A9HA 4NN9A 3HLHA 4X6KA 1L7HA 2XN4A 2BERA 5F72C 4XJZA 1W1XA 1V3CA 5HUGA 3TC9A 1C5KA 2H2UA 4J9TA 3TI3A 1NMAN 4YW3A 4MC7A 2VW2A 5EX7A 3H72A 2ZB5A 1MS8A 2QWCA 2VWDA 2YA4A 1POOA 4HZVA 2IARA 4B7QA 2AEQA 4CH9A
chains in the Genus database with same CATH topology
4L7DA 2ZWAA 4IFNX 4L7BA 2XN4A 3WN7A 4XMBA 1X2RA 5F72C 4YY8A 4CHBA 4IN4A 4IQKA 3ADEA 2DYHA 3ZGDA 5FNSA 3VNGA 1ZGKA 5FNTA 4IFLX 3II7A 4N1BA 5FNUA 3VNHA 2ZZKA 3WDZA 2FLUX 4ZGCA 4ASCA 5FNRA 5FZJA 1U6DX 5FZNA 4ZY3A 2VPJA 4L7CA 5CGJA 4IFJA 2Z32A 5FNQA 1X2JA 2WOZA 2ZW9A 3ZGCA 4CH9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L7D A;  2ZWA A;  4IFN X;  4L7B A;  2XN4 A;  3WN7 A;  4XMB A;  1X2R A;  5F72 C;  4YY8 A;  4CHB A;  4IN4 A;  4IQK A;  3ADE A;  2DYH A;  3ZGD A;  5FNS A;  3VNG A;  1ZGK A;  5FNT A;  4IFL X;  3II7 A;  4N1B A;  5FNU A;  3VNH A;  2ZZK A;  3WDZ A;  2FLU X;  4ZGC A;  4ASC A;  5FNR A;  5FZJ A;  1U6D X;  5FZN A;  4ZY3 A;  2VPJ A;  4L7C A;  5CGJ A;  4IFJ A;  2Z32 A;  5FNQ A;  1X2J A;  2WOZ A;  2ZW9 A;  3ZGC A;  4CH9 A; 
#chains in the Genus database with same CATH topology
 4G3N A;  4XJW A;  1S0J A;  2HTR A;  4HZX A;  4AH4 A;  2IAT A;  1B9S A;  4ZLR A;  4K1H A;  2IAQ A;  2W5O A;  4WEF A;  1W21 A;  1USX A;  2IAS A;  2QWI A;  1EUS A;  4ZGC A;  2W5N A;  2HT8 A;  1NNC A;  3TI4 A;  4FZH A;  3K3A A;  1S18 A;  2QWB A;  4YZ2 A;  2QWG A;  4FPC A;  3NO0 A;  3O4P A;  3SOB B;  4AHA A;  4HZW A;  5FNQ A;  4BBW A;  3V64 C;  3ALX A;  4FOW A;  2VPJ A;  2ZW9 A;  3K36 A;  2A75 A;  4CPN A;  4MWU A;  4B7J A;  1W8N A;  3P5B L;  4O5S A;  2W20 A;  3T1E A;  5F9T A;  4Q6K A;  2SIL A;  3NN9 A;  2AEP A;  2XCY A;  3O9K A;  1NCB N;  1MS9 A;  4MZA A;  1CVM A;  1MZ5 A;  1Q7F A;  1IVD A;  2FP8 A;  4FPJ A;  2XZI A;  2VSM A;  2HTV A;  4GDI A;  4H52 A;  2ZWA A;  4KS4 A;  2AH2 A;  4XJU A;  3S8V A;  2GVV A;  4FPK A;  5JYY A;  4XOG A;  1E1A A;  4GN7 A;  1F8B A;  3AMS A;  1RWI A;  3IAX A;  4IFL X;  4YW2 A;  5HUM A;  3GVJ A;  4MWV A;  4XHX A;  5GX2 A;  2CML A;  4GEZ A;  2W8B A;  3OPZ A;  1BJI A;  1S0I A;  1IVF A;  4SLI A;  3B7E A;  4M3M A;  4YZ1 A;  2Z32 A;  3H73 A;  1V0E A;  1WCQ A;  2HT7 A;  4X4A A;  2V91 A;  2SLI A;  4MWQ A;  1Z4Y A;  3ALW A;  1C9U A;  2HTW A;  4CHB A;  3A72 A;  2YDT A;  1CRZ A;  4R40 A;  1QLG A;  4FOQ A;  1CQ1 A;  4UOU A;  5FNR A;  1INV A;  4M4U A;  4FPO B;  4KS1 A;  5GX4 A;  1W0O A;  5NN9 A;  1DIM A;  2IVZ A;  4FJ6 A;  5EO7 A;  4WEG A;  3ZGC A;  4GNB A;  1NCD N;  2FPB A;  4DG6 A;  4FPY A;  3H71 A;  3WW9 A;  1X2R A;  4MWL A;  2VSK A;  4XHB A;  2YA5 A;  2BF6 A;  1B9T A;  2BAT A;  4GDJ A;  1N1T A;  1XOG A;  1A4G A;  2YA7 A;  4H53 A;  4XJ8 A;  4D4U A;  3L6V A;  4MWX A;  2QWH A;  2VK7 A;  4YZ3 A;  1E8V A;  4C1Y A;  5GTQ A;  1KIT A;  2F10 A;  2F12 A;  2G8S A;  1MS5 A;  2W38 A;  1OFZ A;  2AGS A;  4MJU A;  4CPO A;  4MWR A;  4GZX A;  4XMI A;  4XMB A;  3NSS A;  3SAL A;  2OJH A;  2GVU A;  5HUN A;  3JU4 A;  2C4L A;  1L7F A;  1V3B A;  1A14 N;  2HTU A;  3SOQ A;  3HLI A;  2FHR A;  3WDZ A;  4UF7 A;  4ASC A;  1VCJ A;  4GN8 A;  1XOE A;  2FP9 A;  2IAW A;  2YA6 A;  4M4N A;  1NCC N;  4D52 B;  2F27 A;  1INX A;  1SLL A;  3H6J A;  1QBI A;  1MS3 A;  4XIO A;  2B8H A;  1INF A;  2DG1 A;  3V1S A;  4HHO A;  1V04 A;  2IAU A;  1INY A;  1MWE A;  1B9V A;  3BEQ A;  1W8O A;  4YW4 A;  3SRE A;  2IAX A;  4X47 A;  4XIL A;  4NC5 A;  1WP5 A;  3W09 A;  4O5T A;  1SLI A;  3CL2 A;  3CYE A;  5M1Z A;  3TIB A;  4QN3 A;  3TI6 A;  5D9D A;  1NNA A;  2QWE A;  4HIZ A;  4M4V A;  3S2K A;  3TI8 A;  4YY8 A;  4WA4 A;  1W0P A;  4FPH A;  3FW0 A;  4HZZ A;  4K1J A;  2HT5 A;  3TIC A;  4FQ4 A;  2ZB6 A;  4CPY A;  1N1S A;  4MWY A;  2HTQ A;  4AGI A;  4MJV A;  4GJT A;  4MWW A;  1V0Z A;  3D11 A;  3S94 A;  3V65 B;  1ING A;  3SIL A;  2FPC A;  2IAO A;  3WWA A;  3D12 A;  4GZQ A;  3DR2 A;  1IVC A;  4GNA A;  2QE8 A;  4KS3 A;  4YZ5 A;  3G4H A;  1SUU A;  3HRP A;  2QWF A;  1H6L A;  4FOV A;  1NMC A;  4A0P A;  3SRG A;  4GB1 A;  5H47 A;  3AMR A;  4GN9 A;  4KS2 A;  5D9C A;  2FLU X;  4IYG A;  2XZK A;  1N6D A;  1MS4 A;  5HX0 A;  4D52 C;  2DG0 A;  4JML A;  1CRU A;  4AGT A;  4CSD A;  2QWD A;  4X49 A;  5HUK A;  1F8D A;  4L7D A;  1MZ6 A;  3WN7 A;  1NMB N;  1L7G A;  1V2I A;  1Z50 A;  3FVZ A;  1IVE A;  2DYH A;  4WA5 A;  4CPM A;  4HZY A;  2YDP A;  2VW0 A;  1DIL A;  2F29 A;  1Z4Z A;  2YA8 A;  4GZO A;  1E8T A;  4I00 A;  4JF7 A;  1INW A;  4GZT A;  2H2N A;  1U6D X;  1SNT A;  3GVK A;  5FWW A;  2RKC A;  1E8U A;  5FZN A;  3GVL A;  4D8S A;  1VCU A;  5CGJ A;  4FPL A;  3KYA A;  3E5Z A;  1IJQ A;  2VAQ A;  3Q6P A;  1A4Q A;  3TIA A;  2HU4 A;  2QWK A;  2XZJ A;  2F25 A;  3TI5 A;  2HTY A;  1MR5 A;  5D9B A;  4IQK A;  2W8B B;  5FNS A;  1IUC A;  2HU0 A;  5FNU A;  4HW6 A;  3VNH A;  3CL0 A;  3O9J A;  4MX0 A;  4FPG A;  1V3E A;  5EO8 A;  4XJA A;  2BZD A;  2VK5 A;  1RWL A;  2F11 A;  2IAP A;  4CPZ A;  4QNP A;  4WA3 A;  3U0S A;  4QN6 A;  1F8C A;  1S1D A;  3PJQ A;  3K38 A;  4QN7 A;  1N1V A;  3ADE A;  4FP2 A;  1EUR A;  2X9M A;  1PJX A;  4GNC A;  4QN4 A;  1IVG A;  2QWJ A;  4K1I A;  4FPE A;  4N1B A;  3INB A;  1EUU A;  2ZZK A;  4GZP A;  3K37 A;  1MS1 A;  4XJ9 A;  1Z4X A;  4B7N A;  1N7D A;  2ISM A;  1SO7 A;  4YZ4 A;  4XJR A;  3UC1 A;  2F24 A;  1N6F A;  4CPL A;  4KS5 A;  1W20 A;  2VW1 A;  1NSC A;  2F13 A;  1N6E A;  1IVB A;  4NCS A;  1NCA N;  1USR A;  3LI5 A;  2GVX A;  4FOY A;  4XMA A;  3VNG A;  5FNT A;  3LI3 A;  3II7 A;  4YW5 A;  4Q1U A;  4C1Y B;  1NPE A;  1K32 A;  4XIK A;  4XYX A;  2F0Z A;  1NN2 A;  4ZY3 A;  4B7M A;  4IFJ A;  4FP3 A;  4FPF A;  3G4E A;  5B2C A;  2IAV A;  4PWZ A;  3Q6T A;  3I1C A;  3Q6K A;  4FVK A;  4IFN X;  4L7B A;  5GX5 A;  3SOV A;  1INH A;  1F8E A;  6NN9 A;  3KGG A;  4XE9 A;  3K39 A;  1NSD A;  3B69 A;  4IN4 A;  3ZGD A;  4IMB A;  1IUB A;  5GX1 A;  1N1Y A;  1NSB A;  4MWJ A;  2GVW A;  4QN5 A;  4HHQ A;  5B2D A;  2DSO A;  2F28 A;  3A9G A;  1MS0 A;  4GZW A;  2POO A;  2VK6 A;  4GZS A;  5GX3 A;  2SIM A;  1EUT A;  1X2J A;  2JKB A;  4B7R A;  2WOZ A;  3LI4 A;  4DGR A;  4K1K A;  1V0F A;  2C4A A;  4YW1 A;  4D52 A;  1V3D A;  2GHS A;  1ZGK A;  4MZE A;  3DAS A;  1NNB A;  3S8Z A;  3BYC A;  4XJQ A;  2F26 A;  1WCS A;  1ZI0 A;  3SAN A;  4K3Y A;  3SLI A;  5FZJ A;  2P4O A;  2HQS A;  2QWA A;  4L7C A;  2VVZ A;  1Z4W A;  7NN9 A;  3CKZ A;  1Z4V A;  3A71 A;  3A9H A;  4NN9 A;  3HLH A;  4X6K A;  1L7H A;  2XN4 A;  2BER A;  5F72 C;  4XJZ A;  1W1X A;  1V3C A;  5HUG A;  3TC9 A;  1C5K A;  2H2U A;  4J9T A;  3TI3 A;  1NMA N;  4YW3 A;  4MC7 A;  2VW2 A;  5EX7 A;  3H72 A;  2ZB5 A;  1MS8 A;  2QWC A;  2VWD A;  2YA4 A;  1POO A;  4HZV A;  2IAR A;  4B7Q A;  2AEQ A;  4CH9 A; 
#chains in the Genus database with same CATH homology
 4L7D A;  2ZWA A;  4IFN X;  4L7B A;  2XN4 A;  3WN7 A;  4XMB A;  1X2R A;  5F72 C;  4YY8 A;  4CHB A;  4IN4 A;  4IQK A;  3ADE A;  2DYH A;  3ZGD A;  5FNS A;  3VNG A;  1ZGK A;  5FNT A;  4IFL X;  3II7 A;  4N1B A;  5FNU A;  3VNH A;  2ZZK A;  3WDZ A;  2FLU X;  4ZGC A;  4ASC A;  5FNR A;  5FZJ A;  1U6D X;  5FZN A;  4ZY3 A;  2VPJ A;  4L7C A;  5CGJ A;  4IFJ A;  2Z32 A;  5FNQ A;  1X2J A;  2WOZ A;  2ZW9 A;  3ZGC A;  4CH9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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