3VNHA

Crystal structure of keap1 soaked with synthetic small molecular
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
288
structure length
288
Chain Sequence
PKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Keap1 Soaked with Synthetic Small Molecular
rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords Kelch-like ECH-associated protein 1
total genus 65
structure length 288
sequence length 288
ec nomenclature
pdb deposition date 2012-01-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 3vnhA00
2FLUX 4IN4A 5FNUA 4ZGCA 4L7CA 2DYHA 3II7A 3VNHA 2WOZA 4CHBA 3ADEA 2ZW9A 3ZGDA 5FNRA 3ZGCA 4CH9A 5FZJA 5CGJA 5FZNA 3WN7A 4IFJA 4N1BA 2ZWAA 4L7DA 2VPJA 4XMBA 1X2RA 1U6DX 4ZY3A 3WDZA 4IFLX 2XN4A 3VNGA 1ZGKA 2ZZKA 4IFNX 4L7BA 2Z32A 5F72C 4IQKA 5FNSA 5FNTA 5FNQA 4YY8A 4ASCA 1X2JA
chains in the Genus database with same CATH superfamily
5EO8A 2F13A 3NN9A 1NCBN 2SIMA 1Z4YA 4FPFA 2DSOA 1W1XA 4K1JA 4XMAA 1N7DA 1W0OA 2FP8A 4BBWA 4XILA 5FZJA 4B7NA 2F27A 4CPZA 1NN2A 2VSKA 2AEQA 1OFZA 4GEZA 4MWWA 1EUSA 4K1HA 4XJRA 1X2RA 1B9SA 4X49A 2XZKA 1NSDA 3BYCA 4HZZA 3TI3A 3TI4A 2XN4A 3WWAA 4XYXA 2FPCA 2H2UA 4FOVA 3VNHA 3B7EA 4YW1A 1N1YA 4QNPA 2ZW9A 2VWDA 4G3NA 4YZ2A 5B2CA 1C9UA 1IJQA 1RWLA 1W21A 1V0FA 1WCQA 3HLIA 2B8HA 2VK7A 3SILA 5FWWA 4FOYA 1ZGKA 2AEPA 2QWDA 4B7JA 4YY8A 2VW1A 5FNTA 4FPOB 4ZGCA 4CPNA 3K39A 2DYHA 2IVZA 3GVKA 1XOGA 1SLLA 3G4EA 1S18A 3H72A 5HUGA 1W20A 1S1DA 3TI8A 2SLIA 1N1SA 4DG6A 4XE9A 5FZNA 3K38A 4FPJA 2BERA 4FP3A 4K1IA 5HUNA 4QN6A 2GVVA 5JYYA 3K3AA 2YA7A 3SLIA 4GDJA 5FNSA 1IVBA 3II7A 4AHAA 3A9GA 4MX0A 1L7HA 4GZQA 3WW9A 4GZTA 4MJUA 1WCSA 4CPOA 4FP2A 2C4AA 1N6EA 2HTYA 4GZXA 4H53A 1B9TA 3KYAA 1EUTA 4KS2A 4MWJA 4XJWA 2ZZKA 2YDPA 1V2IA 2HT5A 4IMBA 4CHBA 4FOQA 2G8SA 1F8EA 1INVA 3S8VA 1MZ6A 2BF6A 2QWFA 3TI6A 4XJ8A 1VCJA 3A72A 4YW3A 3V64C 2GHSA 3K37A 5GX4A 1SLIA 4J9TA 3CKZA 4B7RA 2QWIA 4WEFA 4CH9A 3FW0A 4JF7A 2HTVA 3DASA 4GZOA 2F28A 4IN4A 4ASCA 4FJ6A 4X47A 2QWBA 3GVLA 1H6LA 3SALA 3DR2A 1INHA 2DG1A 4MJVA 3O9KA 4FVKA 5GX3A 4GNCA 1DIMA 3HRPA 5GX1A 3K36A 4MWRA 1MS1A 4N1BA 4YZ5A 2YDTA 2QE8A 1MR5A 2F26A 2IAPA 2VPJA 4D8SA 1A4QA 2IAQA 2SILA 1N6FA 1VCUA 3NO0A 4M4UA 1WP5A 3CL0A 7NN9A 5GX2A 1F8DA 5EX7A 5D9CA 3A9HA 3JU4A 2HTUA 4UF7A 4KS5A 4WEGA 2VW2A 5FNRA 4QN3A 4NCSA 5CGJA 2XZIA 3L6VA 4PWZA 1CVMA 2GVWA 1MS9A 2F10A 4YZ1A 3SANA 2YA5A 1CRZA 2JKBA 2W8BB 3KGGA 1Z4WA 4YW2A 3GVJA 1INGA 1V0EA 1V3DA 4M4VA 3G4HA 2F0ZA 4O5TA 1U6DX 2W38A 3UC1A 3WDZA 2ZB5A 3HLHA 4YW5A 1A4GA 4L7BA 3O9JA 5F72C 4C1YB 3OPZA 3H73A 2WOZA 1KITA 4HZVA 3PJQA 4KS3A 3U0SA 3INBA 3SRGA 3ZGCA 4GNAA 2QWCA 1IUBA 1NSCA 1W8OA 1C5KA 3LI5A 1DILA 2C4LA 2F11A 1CRUA 1S0JA 4ZLRA 4YW4A 4D4UA 1IVCA 2HT8A 4I00A 2ZB6A 2ISMA 1ZI0A 4Q6KA 3CL2A 4XJUA 3D11A 4IQKA 4M4NA 3D12A 2DG0A 4CPLA 1L7GA 1MZ5A 4WA3A 2VW0A 4WA4A 1W8NA 3T1EA 4GB1A 3SOQA 3V1SA 4CPMA 2HTRA 4D52C 2F29A 2P4OA 2VSMA 1NMCA 4GN7A 1MS3A 3LI3A 4YZ3A 1CQ1A 1E8TA 1V3BA 4FPYA 1PJXA 4IFJA 2VAQA 1V3CA 2BATA 4HIZA 4SLIA 4MWLA 1BJIA 1MS4A 3Q6TA 4FPLA 4GZSA 3CYEA 2CMLA 2IAVA 4IFNX 2POOA 4MWYA 2AGSA 1USRA 5HX0A 4MC7A 4MWQA 1MS5A 3O4PA 2GVUA 4GJTA 1EUUA 2FHRA 2W8BA 3AMSA 3S94A 1INFA 1V3EA 4JMLA 3TIBA 4AGIA 3FVZA 4GZWA 4C1YA 1B9VA 2QWEA 4YZ4A 4FPGA 4K3YA 1EURA 2YA6A 4X6KA 4ZY3A 1NCCN 2IAWA 4IFLX 3VNGA 4D52B 4WA5A 3SOBB 3I1CA 2VK6A 1QBIA 4XJZA 3A71A 2QWKA 1MWEA 2FP9A 4NC5A 4CPYA 3BEQA 1E8VA 1INWA 3ALWA 5B2DA 1NNAA 4HZYA 3WN7A 3W09A 4R40A 4L7DA 1RWIA 4FOWA 4AH4A 1N6DA 4MWXA 3SOVA 4XJAA 1NNCA 4XJQA 1NMAN 4MWVA 3V65B 4FZHA 4HHOA 4XMIA 5D9BA 3ADEA 1Z50A 4UOUA 2IARA 4XIOA 4HZWA 4GN8A 1IVGA 1K32A 6NN9A 2IATA 3P5BL 2ZWAA 1Q7FA 4B7QA 2XZJA 4GNBA 2W5OA 5D9DA 1USXA 2V91A 1SUUA 4O5SA 1L7FA 2QWAA 2VVZA 4IYGA 4AGTA 4HW6A 1QLGA 1SO7A 2AH2A 1IVFA 1NNBA 2F24A 4L7CA 2W5NA 4FPEA 2W20A 3B69A 4H52A 3TICA 4XHBA 4HHQA 1V0ZA 1F8BA 2A75A 3IAXA 4QN7A 4XHXA 3ALXA 4XIKA 1N1TA 2HQSA 1W0PA 2FPBA 4KS4A 4D52A 1NMBN 5NN9A 3Q6PA 2YA4A 3S8ZA 1INXA 4HZXA 2VK5A 2GVXA 2H2NA 2HU0A 4GDIA 2XCYA 1MS0A 1NCAN 4NN9A 4B7MA 2F25A 1IVEA 3ZGDA 1INYA 2YA8A 1Z4XA 4GN9A 1NPEA 4MZAA 1IVDA 4QN5A 3H6JA 4XMBA 1E1AA 3S2KA 4DGRA 1Z4ZA 4XOGA 2HTWA 4FPKA 2QWJA 5HUKA 4QN4A 2IASA 2RKCA 3E5ZA 4XJ9A 5GTQA 1MS8A 3AMRA 1IUCA 4Q1UA 1X2JA 4GZPA 3LI4A 5FNUA 4MWUA 3H71A 4X4AA 1E8UA 4FPCA 4FPHA 3Q6KA 4K1KA 2F12A 2IAOA 4MZEA 1SNTA 5H47A 1Z4VA 2QWGA 2IAUA 1A14N 4CSDA 3TIAA 5M1ZA 5HUMA 3NSSA 5FNQA 4M3MA 4FQ4A 2FLUX 2HU4A 2QWHA 1N1VA 2HTQA 5F9TA 2OJHA 5GX5A 3SREA 1NCDN 1POOA 1NSBA 4KS1A 3TI5A 3TC9A 1XOEA 1F8CA 4A0PA 1V04A 1S0IA 2HT7A 5EO7A 2IAXA 2Z32A 2BZDA 2X9MA
chains in the Genus database with same CATH topology
2FLUX 4IN4A 5FNUA 4ZGCA 4L7CA 2DYHA 3II7A 3VNHA 2WOZA 4CHBA 3ADEA 2ZW9A 3ZGDA 5FNRA 3ZGCA 4CH9A 5FZJA 5CGJA 5FZNA 3WN7A 4IFJA 4N1BA 2ZWAA 4L7DA 2VPJA 4XMBA 1X2RA 1U6DX 4ZY3A 3WDZA 4IFLX 2XN4A 3VNGA 1ZGKA 2ZZKA 4IFNX 4L7BA 2Z32A 5F72C 4IQKA 5FNSA 5FNTA 5FNQA 4YY8A 4ASCA 1X2JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FLU X;  4IN4 A;  5FNU A;  4ZGC A;  4L7C A;  2DYH A;  3II7 A;  3VNH A;  2WOZ A;  4CHB A;  3ADE A;  2ZW9 A;  3ZGD A;  5FNR A;  3ZGC A;  4CH9 A;  5FZJ A;  5CGJ A;  5FZN A;  3WN7 A;  4IFJ A;  4N1B A;  2ZWA A;  4L7D A;  2VPJ A;  4XMB A;  1X2R A;  1U6D X;  4ZY3 A;  3WDZ A;  4IFL X;  2XN4 A;  3VNG A;  1ZGK A;  2ZZK A;  4IFN X;  4L7B A;  2Z32 A;  5F72 C;  4IQK A;  5FNS A;  5FNT A;  5FNQ A;  4YY8 A;  4ASC A;  1X2J A; 
#chains in the Genus database with same CATH topology
 5EO8 A;  2F13 A;  3NN9 A;  1NCB N;  2SIM A;  1Z4Y A;  4FPF A;  2DSO A;  1W1X A;  4K1J A;  4XMA A;  1N7D A;  1W0O A;  2FP8 A;  4BBW A;  4XIL A;  5FZJ A;  4B7N A;  2F27 A;  4CPZ A;  1NN2 A;  2VSK A;  2AEQ A;  1OFZ A;  4GEZ A;  4MWW A;  1EUS A;  4K1H A;  4XJR A;  1X2R A;  1B9S A;  4X49 A;  2XZK A;  1NSD A;  3BYC A;  4HZZ A;  3TI3 A;  3TI4 A;  2XN4 A;  3WWA A;  4XYX A;  2FPC A;  2H2U A;  4FOV A;  3VNH A;  3B7E A;  4YW1 A;  1N1Y A;  4QNP A;  2ZW9 A;  2VWD A;  4G3N A;  4YZ2 A;  5B2C A;  1C9U A;  1IJQ A;  1RWL A;  1W21 A;  1V0F A;  1WCQ A;  3HLI A;  2B8H A;  2VK7 A;  3SIL A;  5FWW A;  4FOY A;  1ZGK A;  2AEP A;  2QWD A;  4B7J A;  4YY8 A;  2VW1 A;  5FNT A;  4FPO B;  4ZGC A;  4CPN A;  3K39 A;  2DYH A;  2IVZ A;  3GVK A;  1XOG A;  1SLL A;  3G4E A;  1S18 A;  3H72 A;  5HUG A;  1W20 A;  1S1D A;  3TI8 A;  2SLI A;  1N1S A;  4DG6 A;  4XE9 A;  5FZN A;  3K38 A;  4FPJ A;  2BER A;  4FP3 A;  4K1I A;  5HUN A;  4QN6 A;  2GVV A;  5JYY A;  3K3A A;  2YA7 A;  3SLI A;  4GDJ A;  5FNS A;  1IVB A;  3II7 A;  4AHA A;  3A9G A;  4MX0 A;  1L7H A;  4GZQ A;  3WW9 A;  4GZT A;  4MJU A;  1WCS A;  4CPO A;  4FP2 A;  2C4A A;  1N6E A;  2HTY A;  4GZX A;  4H53 A;  1B9T A;  3KYA A;  1EUT A;  4KS2 A;  4MWJ A;  4XJW A;  2ZZK A;  2YDP A;  1V2I A;  2HT5 A;  4IMB A;  4CHB A;  4FOQ A;  2G8S A;  1F8E A;  1INV A;  3S8V A;  1MZ6 A;  2BF6 A;  2QWF A;  3TI6 A;  4XJ8 A;  1VCJ A;  3A72 A;  4YW3 A;  3V64 C;  2GHS A;  3K37 A;  5GX4 A;  1SLI A;  4J9T A;  3CKZ A;  4B7R A;  2QWI A;  4WEF A;  4CH9 A;  3FW0 A;  4JF7 A;  2HTV A;  3DAS A;  4GZO A;  2F28 A;  4IN4 A;  4ASC A;  4FJ6 A;  4X47 A;  2QWB A;  3GVL A;  1H6L A;  3SAL A;  3DR2 A;  1INH A;  2DG1 A;  4MJV A;  3O9K A;  4FVK A;  5GX3 A;  4GNC A;  1DIM A;  3HRP A;  5GX1 A;  3K36 A;  4MWR A;  1MS1 A;  4N1B A;  4YZ5 A;  2YDT A;  2QE8 A;  1MR5 A;  2F26 A;  2IAP A;  2VPJ A;  4D8S A;  1A4Q A;  2IAQ A;  2SIL A;  1N6F A;  1VCU A;  3NO0 A;  4M4U A;  1WP5 A;  3CL0 A;  7NN9 A;  5GX2 A;  1F8D A;  5EX7 A;  5D9C A;  3A9H A;  3JU4 A;  2HTU A;  4UF7 A;  4KS5 A;  4WEG A;  2VW2 A;  5FNR A;  4QN3 A;  4NCS A;  5CGJ A;  2XZI A;  3L6V A;  4PWZ A;  1CVM A;  2GVW A;  1MS9 A;  2F10 A;  4YZ1 A;  3SAN A;  2YA5 A;  1CRZ A;  2JKB A;  2W8B B;  3KGG A;  1Z4W A;  4YW2 A;  3GVJ A;  1ING A;  1V0E A;  1V3D A;  4M4V A;  3G4H A;  2F0Z A;  4O5T A;  1U6D X;  2W38 A;  3UC1 A;  3WDZ A;  2ZB5 A;  3HLH A;  4YW5 A;  1A4G A;  4L7B A;  3O9J A;  5F72 C;  4C1Y B;  3OPZ A;  3H73 A;  2WOZ A;  1KIT A;  4HZV A;  3PJQ A;  4KS3 A;  3U0S A;  3INB A;  3SRG A;  3ZGC A;  4GNA A;  2QWC A;  1IUB A;  1NSC A;  1W8O A;  1C5K A;  3LI5 A;  1DIL A;  2C4L A;  2F11 A;  1CRU A;  1S0J A;  4ZLR A;  4YW4 A;  4D4U A;  1IVC A;  2HT8 A;  4I00 A;  2ZB6 A;  2ISM A;  1ZI0 A;  4Q6K A;  3CL2 A;  4XJU A;  3D11 A;  4IQK A;  4M4N A;  3D12 A;  2DG0 A;  4CPL A;  1L7G A;  1MZ5 A;  4WA3 A;  2VW0 A;  4WA4 A;  1W8N A;  3T1E A;  4GB1 A;  3SOQ A;  3V1S A;  4CPM A;  2HTR A;  4D52 C;  2F29 A;  2P4O A;  2VSM A;  1NMC A;  4GN7 A;  1MS3 A;  3LI3 A;  4YZ3 A;  1CQ1 A;  1E8T A;  1V3B A;  4FPY A;  1PJX A;  4IFJ A;  2VAQ A;  1V3C A;  2BAT A;  4HIZ A;  4SLI A;  4MWL A;  1BJI A;  1MS4 A;  3Q6T A;  4FPL A;  4GZS A;  3CYE A;  2CML A;  2IAV A;  4IFN X;  2POO A;  4MWY A;  2AGS A;  1USR A;  5HX0 A;  4MC7 A;  4MWQ A;  1MS5 A;  3O4P A;  2GVU A;  4GJT A;  1EUU A;  2FHR A;  2W8B A;  3AMS A;  3S94 A;  1INF A;  1V3E A;  4JML A;  3TIB A;  4AGI A;  3FVZ A;  4GZW A;  4C1Y A;  1B9V A;  2QWE A;  4YZ4 A;  4FPG A;  4K3Y A;  1EUR A;  2YA6 A;  4X6K A;  4ZY3 A;  1NCC N;  2IAW A;  4IFL X;  3VNG A;  4D52 B;  4WA5 A;  3SOB B;  3I1C A;  2VK6 A;  1QBI A;  4XJZ A;  3A71 A;  2QWK A;  1MWE A;  2FP9 A;  4NC5 A;  4CPY A;  3BEQ A;  1E8V A;  1INW A;  3ALW A;  5B2D A;  1NNA A;  4HZY A;  3WN7 A;  3W09 A;  4R40 A;  4L7D A;  1RWI A;  4FOW A;  4AH4 A;  1N6D A;  4MWX A;  3SOV A;  4XJA A;  1NNC A;  4XJQ A;  1NMA N;  4MWV A;  3V65 B;  4FZH A;  4HHO A;  4XMI A;  5D9B A;  3ADE A;  1Z50 A;  4UOU A;  2IAR A;  4XIO A;  4HZW A;  4GN8 A;  1IVG A;  1K32 A;  6NN9 A;  2IAT A;  3P5B L;  2ZWA A;  1Q7F A;  4B7Q A;  2XZJ A;  4GNB A;  2W5O A;  5D9D A;  1USX A;  2V91 A;  1SUU A;  4O5S A;  1L7F A;  2QWA A;  2VVZ A;  4IYG A;  4AGT A;  4HW6 A;  1QLG A;  1SO7 A;  2AH2 A;  1IVF A;  1NNB A;  2F24 A;  4L7C A;  2W5N A;  4FPE A;  2W20 A;  3B69 A;  4H52 A;  3TIC A;  4XHB A;  4HHQ A;  1V0Z A;  1F8B A;  2A75 A;  3IAX A;  4QN7 A;  4XHX A;  3ALX A;  4XIK A;  1N1T A;  2HQS A;  1W0P A;  2FPB A;  4KS4 A;  4D52 A;  1NMB N;  5NN9 A;  3Q6P A;  2YA4 A;  3S8Z A;  1INX A;  4HZX A;  2VK5 A;  2GVX A;  2H2N A;  2HU0 A;  4GDI A;  2XCY A;  1MS0 A;  1NCA N;  4NN9 A;  4B7M A;  2F25 A;  1IVE A;  3ZGD A;  1INY A;  2YA8 A;  1Z4X A;  4GN9 A;  1NPE A;  4MZA A;  1IVD A;  4QN5 A;  3H6J A;  4XMB A;  1E1A A;  3S2K A;  4DGR A;  1Z4Z A;  4XOG A;  2HTW A;  4FPK A;  2QWJ A;  5HUK A;  4QN4 A;  2IAS A;  2RKC A;  3E5Z A;  4XJ9 A;  5GTQ A;  1MS8 A;  3AMR A;  1IUC A;  4Q1U A;  1X2J A;  4GZP A;  3LI4 A;  5FNU A;  4MWU A;  3H71 A;  4X4A A;  1E8U A;  4FPC A;  4FPH A;  3Q6K A;  4K1K A;  2F12 A;  2IAO A;  4MZE A;  1SNT A;  5H47 A;  1Z4V A;  2QWG A;  2IAU A;  1A14 N;  4CSD A;  3TIA A;  5M1Z A;  5HUM A;  3NSS A;  5FNQ A;  4M3M A;  4FQ4 A;  2FLU X;  2HU4 A;  2QWH A;  1N1V A;  2HTQ A;  5F9T A;  2OJH A;  5GX5 A;  3SRE A;  1NCD N;  1POO A;  1NSB A;  4KS1 A;  3TI5 A;  3TC9 A;  1XOE A;  1F8C A;  4A0P A;  1V04 A;  1S0I A;  2HT7 A;  5EO7 A;  2IAX A;  2Z32 A;  2BZD A;  2X9M A; 
#chains in the Genus database with same CATH homology
 2FLU X;  4IN4 A;  5FNU A;  4ZGC A;  4L7C A;  2DYH A;  3II7 A;  3VNH A;  2WOZ A;  4CHB A;  3ADE A;  2ZW9 A;  3ZGD A;  5FNR A;  3ZGC A;  4CH9 A;  5FZJ A;  5CGJ A;  5FZN A;  3WN7 A;  4IFJ A;  4N1B A;  2ZWA A;  4L7D A;  2VPJ A;  4XMB A;  1X2R A;  1U6D X;  4ZY3 A;  3WDZ A;  4IFL X;  2XN4 A;  3VNG A;  1ZGK A;  2ZZK A;  4IFN X;  4L7B A;  2Z32 A;  5F72 C;  4IQK A;  5FNS A;  5FNT A;  5FNQ A;  4YY8 A;  4ASC A;  1X2J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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