3WDZA

Crystal structure of keap1 in complex with phosphorylated p62
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
285
structure length
285
Chain Sequence
GRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords Kelch-like ECH-associated protein 1
total genus 63
structure length 285
sequence length 285
ec nomenclature
pdb deposition date 2013-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 3wdzA00
3II7A 1U6DX 2XN4A 4ZGCA 4ZY3A 3ADEA 3WDZA 4L7BA 5FNTA 5FZNA 5FNUA 5FNRA 3VNGA 4CH9A 4L7CA 2Z32A 4IN4A 1X2JA 1ZGKA 5F72C 4XMBA 1X2RA 3ZGCA 5FNSA 2VPJA 2DYHA 5FNQA 4N1BA 3ZGDA 5FZJA 4L7DA 3WN7A 3VNHA 4ASCA 2ZW9A 4IFNX 5CGJA 4IFLX 2WOZA 2ZZKA 2ZWAA 2FLUX 4IFJA 4YY8A 4CHBA 4IQKA
chains in the Genus database with same CATH superfamily
1DILA 4X4AA 1U6DX 3P5BL 4XHXA 1SUUA 1C5KA 2IARA 2BATA 4GZTA 1S0JA 3SOBB 4NC5A 3K3AA 1MS8A 3H71A 1CRUA 2VW1A 4O5TA 4ZLRA 3H72A 1L7GA 1NN2A 4YZ2A 4FPOB 4GNCA 4L7DA 1V0ZA 4KS5A 3HRPA 4MC7A 4QNPA 1SNTA 3HLHA 2VWDA 4IFJA 3S2KA 4YY8A 2VK7A 4MWXA 4M4UA 2HTRA 3K39A 1KITA 3Q6PA 2FP8A 4FPYA 4DGRA 3LI3A 3SANA 4GDJA 1E8VA 3ZGCA 4MWJA 1V3CA 3G4HA 3CKZA 5FNQA 1N1TA 4X47A 3KYAA 1NSCA 1W0PA 2YA8A 1E8UA 1B9SA 4FPJA 4DG6A 2B8HA 4XJWA 5HUMA 4J9TA 5GX5A 4M4VA 4IQKA 4WEGA 4FP2A 3ADEA 4MJUA 5FNTA 5D9BA 2F0ZA 1XOEA 2FP9A 2IAVA 3OPZA 4HHQA 4MZAA 4GNBA 3LI4A 4HZVA 1WCSA 3LI5A 4A0PA 1W20A 3SLIA 2ZW9A 1S0IA 2YA7A 1NMBN 1DIMA 1IUBA 3WW9A 4GNAA 3NSSA 4HW6A 2DSOA 2HTVA 4B7QA 2IAWA 1B9TA 1NMCA 1IVGA 1N1VA 4K1HA 1NCAN 2QWCA 2VAQA 1Z4XA 1RWLA 1A14N 5F9TA 2OJHA 4O5SA 4H52A 4AHAA 4HZYA 4MWRA 1V3DA 2HQSA 2F24A 4X49A 2VVZA 3JU4A 5CGJA 4XE9A 3O4PA 4YZ1A 3AMRA 5GX3A 3BEQA 1INGA 3FW0A 4GB1A 2YDTA 1NCDN 4FPHA 1X2RA 4FVKA 1NPEA 5HUGA 4AGTA 2F13A 6NN9A 2DYHA 4PWZA 2AEQA 1V04A 4HZZA 4AH4A 4FOWA 3DR2A 3TI6A 1IVDA 2GHSA 2HTQA 2WOZA 2XZIA 2GVWA 1Z4WA 1MS3A 2ZB5A 4IMBA 3SILA 1BJIA 7NN9A 3SOVA 2SLIA 2VW2A 1QBIA 1CQ1A 3TI5A 2QWKA 1CVMA 2RKCA 1E8TA 1NNCA 5B2DA 3V65B 4YZ3A 2XZJA 4QN7A 1SO7A 4XJRA 4XMIA 2IAXA 2DG1A 1ZI0A 1IVCA 1CRZA 3A9GA 3II7A 2QWDA 4MX0A 4GZPA 3I1CA 4NCSA 2AGSA 2SIMA 4FPCA 2XCYA 3U0SA 2HT5A 4L7CA 2CMLA 3TIAA 1INYA 1X2JA 1XOGA 2IASA 4HZXA 1W1XA 2VSKA 4WEFA 4FPFA 3CYEA 3Q6TA 3PJQA 4N1BA 3G4EA 5FZJA 5EX7A 2HU4A 4K1JA 2IAPA 1NNAA 4XOGA 1V3EA 3SREA 5EO8A 1S18A 4YZ5A 1N1SA 2ZB6A 4QN6A 1INXA 1L7FA 1PJXA 4H53A 3SOQA 2XN4A 4NN9A 5M1ZA 4XJZA 3S8VA 4FZHA 5FZNA 4YW1A 4XIOA 3S8ZA 3UC1A 3GVJA 4KS2A 2QWGA 1L7HA 4HIZA 5GX4A 5GX1A 2FHRA 4AGIA 4C1YB 2ZWAA 3TI8A 1IUCA 1F8DA 5HUKA 1A4QA 1MS9A 1QLGA 1V2IA 3VNGA 1Q7FA 4QN5A 4M3MA 3BYCA 3H73A 4MWVA 5NN9A 1POOA 1INFA 4YW2A 4D4UA 4K1KA 2YA6A 3FVZA 3K36A 4WA5A 1F8CA 3TI4A 4GZOA 5GTQA 2VSMA 2HTUA 2QWFA 1MWEA 4BBWA 5HX0A 2QWEA 4FJ6A 4IFLX 1Z4VA 4CPOA 1USRA 3CL0A 2IAOA 1W21A 1N6FA 2F26A 2IVZA 3GVLA 3TC9A 2POOA 4FPGA 3WDZA 3A9HA 4MWWA 4L7BA 1OFZA 4MJVA 2VK5A 5FNUA 2W8BA 4YW4A 1ZGKA 4XJ9A 4XYXA 2QWHA 4JF7A 2VK6A 4MZEA 4D52B 1EUUA 2BERA 4YZ4A 3VNHA 1SLLA 4G3NA 1B9VA 2F12A 5D9DA 1V3BA 4GDIA 3B7EA 4ZGCA 1MS5A 2GVXA 4ZY3A 3ALWA 2F11A 2FPBA 2QE8A 3NO0A 1INHA 4GN7A 5F72C 2W38A 5GX2A 5FNSA 4CPZA 3S94A 2VPJA 4B7NA 4FPKA 4XMAA 3NN9A 5B2CA 2BZDA 4Q6KA 3CL2A 4GEZA 4QN3A 1NSDA 3WN7A 4JMLA 4FPLA 4Q1UA 4GZSA 4B7JA 2HTYA 3O9KA 2DG0A 2IATA 2YA5A 1IVFA 5H47A 4B7MA 3Q6KA 4FOYA 2QWJA 3SRGA 1NCBN 4XJUA 2GVVA 5JYYA 5FNRA 2F27A 3K38A 4B7RA 1NSBA 4KS3A 1WP5A 4QN4A 1IVBA 1NMAN 1INVA 1USXA 4CPMA 2IAUA 4UF7A 4GZQA 2HT7A 2A75A 2C4LA 4MWLA 1MS1A 2W5OA 3ALXA 2AH2A 3TICA 5D9CA 3B69A 1EURA 1IVEA 4YW5A 4M4NA 2JKBA 2QWIA 4GZXA 2F29A 4SLIA 2Z32A 3TI3A 4FPEA 1MS4A 2F10A 1F8BA 3W09A 1Z4ZA 2VW0A 4XJ8A 1Z4YA 1V0FA 3SALA 2C4AA 2YA4A 1W8OA 4CSDA 4KS1A 4CPYA 1IJQA 1MZ6A 4ASCA 4CPNA 4XHBA 2AEPA 1MR5A 1S1DA 4K3YA 1INWA 2G8SA 3A72A 2FLUX 3A71A 3V64C 4WA3A 5HUNA 1NNBA 4XJQA 1EUSA 2YDPA 4FOQA 1W0OA 1VCJA 1H6LA 2BF6A 2F25A 4CPLA 3WWAA 4MWYA 2HT8A 3ZGDA 4MWUA 2W5NA 4FQ4A 2V91A 1F8EA 1V0EA 3GVKA 4I00A 4D52C 4IFNX 3KGGA 2P4OA 4D8SA 4XILA 4C1YA 4FOVA 1W8NA 1K32A 3D12A 4CHBA 4XJAA 2W20A 2FPCA 2H2UA 2W8BB 4YW3A 1MS0A 4XMBA 1N6DA 1N1YA 2GVUA 3AMSA 4IYGA 4HHOA 1N7DA 4GZWA 4UOUA 1WCQA 1N6EA 4K1IA 3T1EA 2F28A 2ZZKA 4HZWA 4KS4A 2XZKA 1RWIA 3INBA 3DASA 4GN9A 1VCUA 1EUTA 4R40A 4FP3A 2ISMA 2HTWA 3V1SA 4CH9A 2HU0A 1C9UA 4X6KA 4IN4A 3HLIA 5FWWA 4GN8A 2SILA 3E5ZA 2H2NA 3L6VA 4D52A 1NCCN 3O9JA 3D11A 3IAXA 3K37A 4XIKA 1SLIA 1Z50A 2X9MA 1MZ5A 2QWAA 4MWQA 4WA4A 5EO7A 3TIBA 2QWBA 4GJTA 1A4GA 2IAQA 3H6JA 1E1AA
chains in the Genus database with same CATH topology
3II7A 1U6DX 2XN4A 4ZGCA 4ZY3A 3ADEA 3WDZA 4L7BA 5FNTA 5FZNA 5FNUA 5FNRA 3VNGA 4CH9A 4L7CA 2Z32A 4IN4A 1X2JA 1ZGKA 5F72C 4XMBA 1X2RA 3ZGCA 5FNSA 2VPJA 2DYHA 5FNQA 4N1BA 3ZGDA 5FZJA 4L7DA 3WN7A 3VNHA 4ASCA 2ZW9A 4IFNX 5CGJA 4IFLX 2WOZA 2ZZKA 2ZWAA 2FLUX 4IFJA 4YY8A 4CHBA 4IQKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3II7 A;  1U6D X;  2XN4 A;  4ZGC A;  4ZY3 A;  3ADE A;  3WDZ A;  4L7B A;  5FNT A;  5FZN A;  5FNU A;  5FNR A;  3VNG A;  4CH9 A;  4L7C A;  2Z32 A;  4IN4 A;  1X2J A;  1ZGK A;  5F72 C;  4XMB A;  1X2R A;  3ZGC A;  5FNS A;  2VPJ A;  2DYH A;  5FNQ A;  4N1B A;  3ZGD A;  5FZJ A;  4L7D A;  3WN7 A;  3VNH A;  4ASC A;  2ZW9 A;  4IFN X;  5CGJ A;  4IFL X;  2WOZ A;  2ZZK A;  2ZWA A;  2FLU X;  4IFJ A;  4YY8 A;  4CHB A;  4IQK A; 
#chains in the Genus database with same CATH topology
 1DIL A;  4X4A A;  1U6D X;  3P5B L;  4XHX A;  1SUU A;  1C5K A;  2IAR A;  2BAT A;  4GZT A;  1S0J A;  3SOB B;  4NC5 A;  3K3A A;  1MS8 A;  3H71 A;  1CRU A;  2VW1 A;  4O5T A;  4ZLR A;  3H72 A;  1L7G A;  1NN2 A;  4YZ2 A;  4FPO B;  4GNC A;  4L7D A;  1V0Z A;  4KS5 A;  3HRP A;  4MC7 A;  4QNP A;  1SNT A;  3HLH A;  2VWD A;  4IFJ A;  3S2K A;  4YY8 A;  2VK7 A;  4MWX A;  4M4U A;  2HTR A;  3K39 A;  1KIT A;  3Q6P A;  2FP8 A;  4FPY A;  4DGR A;  3LI3 A;  3SAN A;  4GDJ A;  1E8V A;  3ZGC A;  4MWJ A;  1V3C A;  3G4H A;  3CKZ A;  5FNQ A;  1N1T A;  4X47 A;  3KYA A;  1NSC A;  1W0P A;  2YA8 A;  1E8U A;  1B9S A;  4FPJ A;  4DG6 A;  2B8H A;  4XJW A;  5HUM A;  4J9T A;  5GX5 A;  4M4V A;  4IQK A;  4WEG A;  4FP2 A;  3ADE A;  4MJU A;  5FNT A;  5D9B A;  2F0Z A;  1XOE A;  2FP9 A;  2IAV A;  3OPZ A;  4HHQ A;  4MZA A;  4GNB A;  3LI4 A;  4HZV A;  1WCS A;  3LI5 A;  4A0P A;  1W20 A;  3SLI A;  2ZW9 A;  1S0I A;  2YA7 A;  1NMB N;  1DIM A;  1IUB A;  3WW9 A;  4GNA A;  3NSS A;  4HW6 A;  2DSO A;  2HTV A;  4B7Q A;  2IAW A;  1B9T A;  1NMC A;  1IVG A;  1N1V A;  4K1H A;  1NCA N;  2QWC A;  2VAQ A;  1Z4X A;  1RWL A;  1A14 N;  5F9T A;  2OJH A;  4O5S A;  4H52 A;  4AHA A;  4HZY A;  4MWR A;  1V3D A;  2HQS A;  2F24 A;  4X49 A;  2VVZ A;  3JU4 A;  5CGJ A;  4XE9 A;  3O4P A;  4YZ1 A;  3AMR A;  5GX3 A;  3BEQ A;  1ING A;  3FW0 A;  4GB1 A;  2YDT A;  1NCD N;  4FPH A;  1X2R A;  4FVK A;  1NPE A;  5HUG A;  4AGT A;  2F13 A;  6NN9 A;  2DYH A;  4PWZ A;  2AEQ A;  1V04 A;  4HZZ A;  4AH4 A;  4FOW A;  3DR2 A;  3TI6 A;  1IVD A;  2GHS A;  2HTQ A;  2WOZ A;  2XZI A;  2GVW A;  1Z4W A;  1MS3 A;  2ZB5 A;  4IMB A;  3SIL A;  1BJI A;  7NN9 A;  3SOV A;  2SLI A;  2VW2 A;  1QBI A;  1CQ1 A;  3TI5 A;  2QWK A;  1CVM A;  2RKC A;  1E8T A;  1NNC A;  5B2D A;  3V65 B;  4YZ3 A;  2XZJ A;  4QN7 A;  1SO7 A;  4XJR A;  4XMI A;  2IAX A;  2DG1 A;  1ZI0 A;  1IVC A;  1CRZ A;  3A9G A;  3II7 A;  2QWD A;  4MX0 A;  4GZP A;  3I1C A;  4NCS A;  2AGS A;  2SIM A;  4FPC A;  2XCY A;  3U0S A;  2HT5 A;  4L7C A;  2CML A;  3TIA A;  1INY A;  1X2J A;  1XOG A;  2IAS A;  4HZX A;  1W1X A;  2VSK A;  4WEF A;  4FPF A;  3CYE A;  3Q6T A;  3PJQ A;  4N1B A;  3G4E A;  5FZJ A;  5EX7 A;  2HU4 A;  4K1J A;  2IAP A;  1NNA A;  4XOG A;  1V3E A;  3SRE A;  5EO8 A;  1S18 A;  4YZ5 A;  1N1S A;  2ZB6 A;  4QN6 A;  1INX A;  1L7F A;  1PJX A;  4H53 A;  3SOQ A;  2XN4 A;  4NN9 A;  5M1Z A;  4XJZ A;  3S8V A;  4FZH A;  5FZN A;  4YW1 A;  4XIO A;  3S8Z A;  3UC1 A;  3GVJ A;  4KS2 A;  2QWG A;  1L7H A;  4HIZ A;  5GX4 A;  5GX1 A;  2FHR A;  4AGI A;  4C1Y B;  2ZWA A;  3TI8 A;  1IUC A;  1F8D A;  5HUK A;  1A4Q A;  1MS9 A;  1QLG A;  1V2I A;  3VNG A;  1Q7F A;  4QN5 A;  4M3M A;  3BYC A;  3H73 A;  4MWV A;  5NN9 A;  1POO A;  1INF A;  4YW2 A;  4D4U A;  4K1K A;  2YA6 A;  3FVZ A;  3K36 A;  4WA5 A;  1F8C A;  3TI4 A;  4GZO A;  5GTQ A;  2VSM A;  2HTU A;  2QWF A;  1MWE A;  4BBW A;  5HX0 A;  2QWE A;  4FJ6 A;  4IFL X;  1Z4V A;  4CPO A;  1USR A;  3CL0 A;  2IAO A;  1W21 A;  1N6F A;  2F26 A;  2IVZ A;  3GVL A;  3TC9 A;  2POO A;  4FPG A;  3WDZ A;  3A9H A;  4MWW A;  4L7B A;  1OFZ A;  4MJV A;  2VK5 A;  5FNU A;  2W8B A;  4YW4 A;  1ZGK A;  4XJ9 A;  4XYX A;  2QWH A;  4JF7 A;  2VK6 A;  4MZE A;  4D52 B;  1EUU A;  2BER A;  4YZ4 A;  3VNH A;  1SLL A;  4G3N A;  1B9V A;  2F12 A;  5D9D A;  1V3B A;  4GDI A;  3B7E A;  4ZGC A;  1MS5 A;  2GVX A;  4ZY3 A;  3ALW A;  2F11 A;  2FPB A;  2QE8 A;  3NO0 A;  1INH A;  4GN7 A;  5F72 C;  2W38 A;  5GX2 A;  5FNS A;  4CPZ A;  3S94 A;  2VPJ A;  4B7N A;  4FPK A;  4XMA A;  3NN9 A;  5B2C A;  2BZD A;  4Q6K A;  3CL2 A;  4GEZ A;  4QN3 A;  1NSD A;  3WN7 A;  4JML A;  4FPL A;  4Q1U A;  4GZS A;  4B7J A;  2HTY A;  3O9K A;  2DG0 A;  2IAT A;  2YA5 A;  1IVF A;  5H47 A;  4B7M A;  3Q6K A;  4FOY A;  2QWJ A;  3SRG A;  1NCB N;  4XJU A;  2GVV A;  5JYY A;  5FNR A;  2F27 A;  3K38 A;  4B7R A;  1NSB A;  4KS3 A;  1WP5 A;  4QN4 A;  1IVB A;  1NMA N;  1INV A;  1USX A;  4CPM A;  2IAU A;  4UF7 A;  4GZQ A;  2HT7 A;  2A75 A;  2C4L A;  4MWL A;  1MS1 A;  2W5O A;  3ALX A;  2AH2 A;  3TIC A;  5D9C A;  3B69 A;  1EUR A;  1IVE A;  4YW5 A;  4M4N A;  2JKB A;  2QWI A;  4GZX A;  2F29 A;  4SLI A;  2Z32 A;  3TI3 A;  4FPE A;  1MS4 A;  2F10 A;  1F8B A;  3W09 A;  1Z4Z A;  2VW0 A;  4XJ8 A;  1Z4Y A;  1V0F A;  3SAL A;  2C4A A;  2YA4 A;  1W8O A;  4CSD A;  4KS1 A;  4CPY A;  1IJQ A;  1MZ6 A;  4ASC A;  4CPN A;  4XHB A;  2AEP A;  1MR5 A;  1S1D A;  4K3Y A;  1INW A;  2G8S A;  3A72 A;  2FLU X;  3A71 A;  3V64 C;  4WA3 A;  5HUN A;  1NNB A;  4XJQ A;  1EUS A;  2YDP A;  4FOQ A;  1W0O A;  1VCJ A;  1H6L A;  2BF6 A;  2F25 A;  4CPL A;  3WWA A;  4MWY A;  2HT8 A;  3ZGD A;  4MWU A;  2W5N A;  4FQ4 A;  2V91 A;  1F8E A;  1V0E A;  3GVK A;  4I00 A;  4D52 C;  4IFN X;  3KGG A;  2P4O A;  4D8S A;  4XIL A;  4C1Y A;  4FOV A;  1W8N A;  1K32 A;  3D12 A;  4CHB A;  4XJA A;  2W20 A;  2FPC A;  2H2U A;  2W8B B;  4YW3 A;  1MS0 A;  4XMB A;  1N6D A;  1N1Y A;  2GVU A;  3AMS A;  4IYG A;  4HHO A;  1N7D A;  4GZW A;  4UOU A;  1WCQ A;  1N6E A;  4K1I A;  3T1E A;  2F28 A;  2ZZK A;  4HZW A;  4KS4 A;  2XZK A;  1RWI A;  3INB A;  3DAS A;  4GN9 A;  1VCU A;  1EUT A;  4R40 A;  4FP3 A;  2ISM A;  2HTW A;  3V1S A;  4CH9 A;  2HU0 A;  1C9U A;  4X6K A;  4IN4 A;  3HLI A;  5FWW A;  4GN8 A;  2SIL A;  3E5Z A;  2H2N A;  3L6V A;  4D52 A;  1NCC N;  3O9J A;  3D11 A;  3IAX A;  3K37 A;  4XIK A;  1SLI A;  1Z50 A;  2X9M A;  1MZ5 A;  2QWA A;  4MWQ A;  4WA4 A;  5EO7 A;  3TIB A;  2QWB A;  4GJT A;  1A4G A;  2IAQ A;  3H6J A;  1E1A A; 
#chains in the Genus database with same CATH homology
 3II7 A;  1U6D X;  2XN4 A;  4ZGC A;  4ZY3 A;  3ADE A;  3WDZ A;  4L7B A;  5FNT A;  5FZN A;  5FNU A;  5FNR A;  3VNG A;  4CH9 A;  4L7C A;  2Z32 A;  4IN4 A;  1X2J A;  1ZGK A;  5F72 C;  4XMB A;  1X2R A;  3ZGC A;  5FNS A;  2VPJ A;  2DYH A;  5FNQ A;  4N1B A;  3ZGD A;  5FZJ A;  4L7D A;  3WN7 A;  3VNH A;  4ASC A;  2ZW9 A;  4IFN X;  5CGJ A;  4IFL X;  2WOZ A;  2ZZK A;  2ZWA A;  2FLU X;  4IFJ A;  4YY8 A;  4CHB A;  4IQK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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