3WN7A

Crystal structure of keap1 in complex with the n-terminal region of the nrf2 transcription factor
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
286
structure length
286
Chain Sequence
VGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDGHIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYDGHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Kinetic, thermodynamic, and structural characterizations of the association between Nrf2-DLGex degron and Keap1
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords Kelch-like ECH-associated protein 1
total genus 64
structure length 286
sequence length 286
chains with identical sequence L
ec nomenclature
pdb deposition date 2013-12-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 3wn7A00
4YY8A 4ASCA 2ZZKA 1X2RA 1X2JA 5FZNA 5FNQA 2DYHA 4IFJA 4IFLX 1ZGKA 3II7A 4CHBA 4N1BA 4L7DA 5FZJA 4ZGCA 1U6DX 2FLUX 5FNTA 5F72C 2Z32A 5FNUA 5FNSA 3VNHA 3ZGCA 4IFNX 3ADEA 4L7CA 4ZY3A 2VPJA 4CH9A 2XN4A 5CGJA 4IN4A 4XMBA 3VNGA 3WN7A 5FNRA 4L7BA 3ZGDA 3WDZA 2ZWAA 2ZW9A 2WOZA 4IQKA
chains in the Genus database with same CATH superfamily
2RKCA 4XJ9A 1NNAA 2W5OA 4AH4A 4M4UA 1ZGKA 2C4AA 2YA6A 3SILA 4WA5A 1B9SA 2FLUX 3VNHA 2ZB6A 1B9VA 2BZDA 2DG1A 2YA5A 4FP3A 4SLIA 4QN4A 4CH9A 4GZXA 3A72A 5HX0A 3O4PA 2QE8A 2IARA 4L7BA 3HLHA 2F24A 1A4QA 1IVFA 2ZW9A 4QN5A 4KS5A 4CPMA 1CRZA 2IAOA 3SOQA 2YA4A 3IAXA 3L6VA 1F8EA 5B2DA 1IVEA 5H47A 1IUBA 2Z32A 1INXA 2HTYA 4XJUA 3S2KA 1SLIA 1IJQA 4XHXA 2ZB5A 2HT8A 4DG6A 1INWA 4MX0A 2W8BA 3TI6A 4NCSA 5HUNA 1USXA 1MS0A 4C1YB 4CPYA 2QWFA 4KS3A 3A9GA 2IAQA 4FPLA 5GX1A 1F8CA 3S8ZA 4IYGA 4FOWA 2CMLA 4IQKA 3SOVA 2OJHA 4AHAA 1X2JA 5FZNA 4FQ4A 4YZ2A 2DYHA 2SILA 3FVZA 3FW0A 2VVZA 4L7DA 1INHA 2F13A 1IVDA 4FOYA 4GZTA 3Q6KA 3SRGA 1Z50A 5B2CA 1MZ6A 3TICA 2GVUA 2IAXA 4YZ3A 1XOEA 3INBA 1S0IA 2YA7A 4AGTA 1L7FA 3DR2A 4UOUA 1MR5A 4X47A 4XE9A 6NN9A 1Z4XA 1Z4ZA 4FPFA 2QWBA 3LI4A 1N1YA 4D4UA 1E8UA 1W21A 3K36A 4K3YA 4HZYA 1DILA 4NC5A 2F25A 4K1IA 2DSOA 2ISMA 2VW0A 1W8OA 1WCQA 1Z4VA 1L7GA 1V3CA 4QN7A 2AEPA 3W09A 4MWRA 3CKZA 1N1SA 2HQSA 3HLIA 3II7A 1RWLA 1B9TA 2BERA 1VCJA 2HT7A 3H71A 4MJUA 1PJXA 4CPZA 3Q6TA 3CYEA 4R40A 4X6KA 1VCUA 3ADEA 4ZY3A 4DGRA 5JYYA 4FZHA 1NCCN 2VWDA 4GZQA 4HZZA 4M4VA 4GDIA 4YZ4A 1POOA 3U0SA 4MWXA 5CGJA 4M4NA 4GB1A 4CPOA 4NN9A 3WN7A 1S1DA 5FNRA 3ZGDA 4MZAA 4YZ5A 4H53A 3BEQA 3G4EA 4MJVA 4MZEA 1CVMA 2HTWA 4IFJA 4XOGA 2X9MA 3PJQA 2XZKA 1U6DX 4FPYA 2F0ZA 5FNTA 2F28A 4Q1UA 1EURA 1ZI0A 4XIOA 4IFNX 4D52B 4FPCA 5GTQA 3K37A 5HUGA 4O5SA 1QBIA 2FPCA 3D11A 3A71A 3B7EA 4FPGA 4YW1A 1H6LA 2ZWAA 2GHSA 4B7JA 2H2UA 4WEGA 4YW4A 3K3AA 4FPHA 4XJWA 1V0ZA 2W20A 2V91A 1N6EA 4GZWA 3S8VA 1EUUA 1SO7A 5F72C 2QWAA 2VPJA 4MWWA 4B7QA 2BF6A 1NNCA 4HIZA 3Q6PA 4YZ1A 5GX2A 1NPEA 4HHOA 3NO0A 2AH2A 2VK5A 1V2IA 1QLGA 4ASCA 2ZZKA 1IVCA 3GVLA 2W38A 7NN9A 4N1BA 2QWJA 5FZJA 4GZSA 1SNTA 3BYCA 5M1ZA 1INYA 5F9TA 2W8BB 1EUTA 4UF7A 2GVWA 1K32A 2QWEA 4XMBA 3TC9A 2GVVA 3DASA 2G8SA 4HZWA 4XJQA 2POOA 4CSDA 3LI3A 1IVGA 3A9HA 4I00A 1NMAN 1E1AA 1F8BA 3KYAA 4B7NA 3TI4A 5FNSA 1SUUA 4QNPA 4YW3A 5EO8A 4XYXA 3K39A 3SREA 3TI5A 2QWIA 3T1EA 4XJRA 4M3MA 4XILA 4GNBA 1OFZA 4B7RA 4CPLA 4GNAA 5D9CA 3H6JA 3H72A 2IVZA 4MWVA 4XJAA 5NN9A 2QWGA 2SIMA 1W0PA 3SANA 4KS1A 3NSSA 5HUMA 4XIKA 1S0JA 1CRUA 1NN2A 4KS4A 4QN3A 2H2NA 4X4AA 2F27A 5FNUA 4MWQA 4FPKA 4ZLRA 4PWZA 4O5TA 3O9KA 1L7HA 4HZXA 2JKBA 1C5KA 1F8DA 4WA3A 1BJIA 3ALXA 4K1KA 4MWLA 3V65B 2WOZA 4J9TA 3WWAA 1NSCA 2VSMA 2IAVA 3CL2A 3K38A 4HHQA 4JF7A 1INFA 4GDJA 3TIBA 2YDTA 3TI8A 4XJ8A 1DIMA 2SLIA 3ALWA 4L7CA 2HT5A 3SOBB 1NNBA 1V3DA 5EO7A 3D12A 3I1CA 2QWDA 2FP8A 5HUKA 4Q6KA 1MS1A 4AGIA 4YY8A 5GX4A 1X2RA 5FNQA 4IFLX 1EUSA 3V64C 4A0PA 1V0EA 4MC7A 3SLIA 4MWYA 1V3EA 4FJ6A 1CQ1A 4YW2A 2P4OA 4D8SA 3ZGCA 1W20A 1NMCA 1USRA 2VSKA 4C1YA 1Z4YA 2A75A 4BBWA 1MWEA 2XN4A 1MS3A 2QWKA 2QWCA 2IAPA 1A14N 2AEQA 5D9BA 3AMSA 2VK6A 2HTQA 1E8VA 2IAUA 4G3NA 2HTRA 4MWJA 4D52C 2HTUA 2VW2A 2W5NA 1MS8A 1V3BA 2FPBA 4FOVA 3KGGA 2IASA 1MZ5A 1V0FA 3P5BL 1NSDA 4JMLA 1INVA 2VAQA 1N1VA 4FPEA 4WA4A 2F12A 2HU4A 4MWUA 3GVKA 3JU4A 2XZIA 1N7DA 4B7MA 1N1TA 4X49A 2AGSA 2FP9A 3HRPA 3NN9A 3G4HA 1NMBN 4GN8A 1Z4WA 4K1JA 4ZGCA 4IMBA 3TIAA 3UC1A 1E8TA 3OPZA 4GZPA 4XMIA 4HW6A 1C9UA 1NCBN 4XJZA 1SLLA 2F29A 4XMAA 1S18A 4GJTA 1KITA 4WEFA 2GVXA 2VW1A 1W1XA 3O9JA 2QWHA 4HZVA 1MS5A 1MS4A 3GVJA 1V04A 2HU0A 4XHBA 4CHBA 2HTVA 2XZJA 1WCSA 1IVBA 1WP5A 4K1HA 3WW9A 2YA8A 4QN6A 3B69A 4FP2A 1RWIA 4GN9A 4KS2A 2B8HA 1W0OA 4GEZA 4GN7A 1Q7FA 1IUCA 5FWWA 3WDZA 1A4GA 2FHRA 1W8NA 3AMRA 4GNCA 1NCAN 4GZOA 4H52A 2F26A 2BATA 4CPNA 4FVKA 5EX7A 2DG0A 4YW5A 1N6DA 3S94A 2F10A 2IAWA 2IATA 2YDPA 1N6FA 3LI5A 4FOQA 4FPOB 1INGA 5GX5A 4D52A 5GX3A 2VK7A 2C4LA 3SALA 3H73A 3E5ZA 3V1SA 3CL0A 4IN4A 3VNGA 1NCDN 1MS9A 2XCYA 5D9DA 1XOGA 2F11A 3TI3A 4FPJA 1NSBA
chains in the Genus database with same CATH topology
4YY8A 4ASCA 2ZZKA 1X2RA 1X2JA 5FZNA 5FNQA 2DYHA 4IFJA 4IFLX 1ZGKA 3II7A 4CHBA 4N1BA 4L7DA 5FZJA 4ZGCA 1U6DX 2FLUX 5FNTA 5F72C 2Z32A 5FNUA 5FNSA 3VNHA 3ZGCA 4IFNX 3ADEA 4L7CA 4ZY3A 2VPJA 4CH9A 2XN4A 5CGJA 4IN4A 4XMBA 3VNGA 3WN7A 5FNRA 4L7BA 3ZGDA 3WDZA 2ZWAA 2ZW9A 2WOZA 4IQKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YY8 A;  4ASC A;  2ZZK A;  1X2R A;  1X2J A;  5FZN A;  5FNQ A;  2DYH A;  4IFJ A;  4IFL X;  1ZGK A;  3II7 A;  4CHB A;  4N1B A;  4L7D A;  5FZJ A;  4ZGC A;  1U6D X;  2FLU X;  5FNT A;  5F72 C;  2Z32 A;  5FNU A;  5FNS A;  3VNH A;  3ZGC A;  4IFN X;  3ADE A;  4L7C A;  4ZY3 A;  2VPJ A;  4CH9 A;  2XN4 A;  5CGJ A;  4IN4 A;  4XMB A;  3VNG A;  3WN7 A;  5FNR A;  4L7B A;  3ZGD A;  3WDZ A;  2ZWA A;  2ZW9 A;  2WOZ A;  4IQK A; 
#chains in the Genus database with same CATH topology
 2RKC A;  4XJ9 A;  1NNA A;  2W5O A;  4AH4 A;  4M4U A;  1ZGK A;  2C4A A;  2YA6 A;  3SIL A;  4WA5 A;  1B9S A;  2FLU X;  3VNH A;  2ZB6 A;  1B9V A;  2BZD A;  2DG1 A;  2YA5 A;  4FP3 A;  4SLI A;  4QN4 A;  4CH9 A;  4GZX A;  3A72 A;  5HX0 A;  3O4P A;  2QE8 A;  2IAR A;  4L7B A;  3HLH A;  2F24 A;  1A4Q A;  1IVF A;  2ZW9 A;  4QN5 A;  4KS5 A;  4CPM A;  1CRZ A;  2IAO A;  3SOQ A;  2YA4 A;  3IAX A;  3L6V A;  1F8E A;  5B2D A;  1IVE A;  5H47 A;  1IUB A;  2Z32 A;  1INX A;  2HTY A;  4XJU A;  3S2K A;  1SLI A;  1IJQ A;  4XHX A;  2ZB5 A;  2HT8 A;  4DG6 A;  1INW A;  4MX0 A;  2W8B A;  3TI6 A;  4NCS A;  5HUN A;  1USX A;  1MS0 A;  4C1Y B;  4CPY A;  2QWF A;  4KS3 A;  3A9G A;  2IAQ A;  4FPL A;  5GX1 A;  1F8C A;  3S8Z A;  4IYG A;  4FOW A;  2CML A;  4IQK A;  3SOV A;  2OJH A;  4AHA A;  1X2J A;  5FZN A;  4FQ4 A;  4YZ2 A;  2DYH A;  2SIL A;  3FVZ A;  3FW0 A;  2VVZ A;  4L7D A;  1INH A;  2F13 A;  1IVD A;  4FOY A;  4GZT A;  3Q6K A;  3SRG A;  1Z50 A;  5B2C A;  1MZ6 A;  3TIC A;  2GVU A;  2IAX A;  4YZ3 A;  1XOE A;  3INB A;  1S0I A;  2YA7 A;  4AGT A;  1L7F A;  3DR2 A;  4UOU A;  1MR5 A;  4X47 A;  4XE9 A;  6NN9 A;  1Z4X A;  1Z4Z A;  4FPF A;  2QWB A;  3LI4 A;  1N1Y A;  4D4U A;  1E8U A;  1W21 A;  3K36 A;  4K3Y A;  4HZY A;  1DIL A;  4NC5 A;  2F25 A;  4K1I A;  2DSO A;  2ISM A;  2VW0 A;  1W8O A;  1WCQ A;  1Z4V A;  1L7G A;  1V3C A;  4QN7 A;  2AEP A;  3W09 A;  4MWR A;  3CKZ A;  1N1S A;  2HQS A;  3HLI A;  3II7 A;  1RWL A;  1B9T A;  2BER A;  1VCJ A;  2HT7 A;  3H71 A;  4MJU A;  1PJX A;  4CPZ A;  3Q6T A;  3CYE A;  4R40 A;  4X6K A;  1VCU A;  3ADE A;  4ZY3 A;  4DGR A;  5JYY A;  4FZH A;  1NCC N;  2VWD A;  4GZQ A;  4HZZ A;  4M4V A;  4GDI A;  4YZ4 A;  1POO A;  3U0S A;  4MWX A;  5CGJ A;  4M4N A;  4GB1 A;  4CPO A;  4NN9 A;  3WN7 A;  1S1D A;  5FNR A;  3ZGD A;  4MZA A;  4YZ5 A;  4H53 A;  3BEQ A;  3G4E A;  4MJV A;  4MZE A;  1CVM A;  2HTW A;  4IFJ A;  4XOG A;  2X9M A;  3PJQ A;  2XZK A;  1U6D X;  4FPY A;  2F0Z A;  5FNT A;  2F28 A;  4Q1U A;  1EUR A;  1ZI0 A;  4XIO A;  4IFN X;  4D52 B;  4FPC A;  5GTQ A;  3K37 A;  5HUG A;  4O5S A;  1QBI A;  2FPC A;  3D11 A;  3A71 A;  3B7E A;  4FPG A;  4YW1 A;  1H6L A;  2ZWA A;  2GHS A;  4B7J A;  2H2U A;  4WEG A;  4YW4 A;  3K3A A;  4FPH A;  4XJW A;  1V0Z A;  2W20 A;  2V91 A;  1N6E A;  4GZW A;  3S8V A;  1EUU A;  1SO7 A;  5F72 C;  2QWA A;  2VPJ A;  4MWW A;  4B7Q A;  2BF6 A;  1NNC A;  4HIZ A;  3Q6P A;  4YZ1 A;  5GX2 A;  1NPE A;  4HHO A;  3NO0 A;  2AH2 A;  2VK5 A;  1V2I A;  1QLG A;  4ASC A;  2ZZK A;  1IVC A;  3GVL A;  2W38 A;  7NN9 A;  4N1B A;  2QWJ A;  5FZJ A;  4GZS A;  1SNT A;  3BYC A;  5M1Z A;  1INY A;  5F9T A;  2W8B B;  1EUT A;  4UF7 A;  2GVW A;  1K32 A;  2QWE A;  4XMB A;  3TC9 A;  2GVV A;  3DAS A;  2G8S A;  4HZW A;  4XJQ A;  2POO A;  4CSD A;  3LI3 A;  1IVG A;  3A9H A;  4I00 A;  1NMA N;  1E1A A;  1F8B A;  3KYA A;  4B7N A;  3TI4 A;  5FNS A;  1SUU A;  4QNP A;  4YW3 A;  5EO8 A;  4XYX A;  3K39 A;  3SRE A;  3TI5 A;  2QWI A;  3T1E A;  4XJR A;  4M3M A;  4XIL A;  4GNB A;  1OFZ A;  4B7R A;  4CPL A;  4GNA A;  5D9C A;  3H6J A;  3H72 A;  2IVZ A;  4MWV A;  4XJA A;  5NN9 A;  2QWG A;  2SIM A;  1W0P A;  3SAN A;  4KS1 A;  3NSS A;  5HUM A;  4XIK A;  1S0J A;  1CRU A;  1NN2 A;  4KS4 A;  4QN3 A;  2H2N A;  4X4A A;  2F27 A;  5FNU A;  4MWQ A;  4FPK A;  4ZLR A;  4PWZ A;  4O5T A;  3O9K A;  1L7H A;  4HZX A;  2JKB A;  1C5K A;  1F8D A;  4WA3 A;  1BJI A;  3ALX A;  4K1K A;  4MWL A;  3V65 B;  2WOZ A;  4J9T A;  3WWA A;  1NSC A;  2VSM A;  2IAV A;  3CL2 A;  3K38 A;  4HHQ A;  4JF7 A;  1INF A;  4GDJ A;  3TIB A;  2YDT A;  3TI8 A;  4XJ8 A;  1DIM A;  2SLI A;  3ALW A;  4L7C A;  2HT5 A;  3SOB B;  1NNB A;  1V3D A;  5EO7 A;  3D12 A;  3I1C A;  2QWD A;  2FP8 A;  5HUK A;  4Q6K A;  1MS1 A;  4AGI A;  4YY8 A;  5GX4 A;  1X2R A;  5FNQ A;  4IFL X;  1EUS A;  3V64 C;  4A0P A;  1V0E A;  4MC7 A;  3SLI A;  4MWY A;  1V3E A;  4FJ6 A;  1CQ1 A;  4YW2 A;  2P4O A;  4D8S A;  3ZGC A;  1W20 A;  1NMC A;  1USR A;  2VSK A;  4C1Y A;  1Z4Y A;  2A75 A;  4BBW A;  1MWE A;  2XN4 A;  1MS3 A;  2QWK A;  2QWC A;  2IAP A;  1A14 N;  2AEQ A;  5D9B A;  3AMS A;  2VK6 A;  2HTQ A;  1E8V A;  2IAU A;  4G3N A;  2HTR A;  4MWJ A;  4D52 C;  2HTU A;  2VW2 A;  2W5N A;  1MS8 A;  1V3B A;  2FPB A;  4FOV A;  3KGG A;  2IAS A;  1MZ5 A;  1V0F A;  3P5B L;  1NSD A;  4JML A;  1INV A;  2VAQ A;  1N1V A;  4FPE A;  4WA4 A;  2F12 A;  2HU4 A;  4MWU A;  3GVK A;  3JU4 A;  2XZI A;  1N7D A;  4B7M A;  1N1T A;  4X49 A;  2AGS A;  2FP9 A;  3HRP A;  3NN9 A;  3G4H A;  1NMB N;  4GN8 A;  1Z4W A;  4K1J A;  4ZGC A;  4IMB A;  3TIA A;  3UC1 A;  1E8T A;  3OPZ A;  4GZP A;  4XMI A;  4HW6 A;  1C9U A;  1NCB N;  4XJZ A;  1SLL A;  2F29 A;  4XMA A;  1S18 A;  4GJT A;  1KIT A;  4WEF A;  2GVX A;  2VW1 A;  1W1X A;  3O9J A;  2QWH A;  4HZV A;  1MS5 A;  1MS4 A;  3GVJ A;  1V04 A;  2HU0 A;  4XHB A;  4CHB A;  2HTV A;  2XZJ A;  1WCS A;  1IVB A;  1WP5 A;  4K1H A;  3WW9 A;  2YA8 A;  4QN6 A;  3B69 A;  4FP2 A;  1RWI A;  4GN9 A;  4KS2 A;  2B8H A;  1W0O A;  4GEZ A;  4GN7 A;  1Q7F A;  1IUC A;  5FWW A;  3WDZ A;  1A4G A;  2FHR A;  1W8N A;  3AMR A;  4GNC A;  1NCA N;  4GZO A;  4H52 A;  2F26 A;  2BAT A;  4CPN A;  4FVK A;  5EX7 A;  2DG0 A;  4YW5 A;  1N6D A;  3S94 A;  2F10 A;  2IAW A;  2IAT A;  2YDP A;  1N6F A;  3LI5 A;  4FOQ A;  4FPO B;  1ING A;  5GX5 A;  4D52 A;  5GX3 A;  2VK7 A;  2C4L A;  3SAL A;  3H73 A;  3E5Z A;  3V1S A;  3CL0 A;  4IN4 A;  3VNG A;  1NCD N;  1MS9 A;  2XCY A;  5D9D A;  1XOG A;  2F11 A;  3TI3 A;  4FPJ A;  1NSB A; 
#chains in the Genus database with same CATH homology
 4YY8 A;  4ASC A;  2ZZK A;  1X2R A;  1X2J A;  5FZN A;  5FNQ A;  2DYH A;  4IFJ A;  4IFL X;  1ZGK A;  3II7 A;  4CHB A;  4N1B A;  4L7D A;  5FZJ A;  4ZGC A;  1U6D X;  2FLU X;  5FNT A;  5F72 C;  2Z32 A;  5FNU A;  5FNS A;  3VNH A;  3ZGC A;  4IFN X;  3ADE A;  4L7C A;  4ZY3 A;  2VPJ A;  4CH9 A;  2XN4 A;  5CGJ A;  4IN4 A;  4XMB A;  3VNG A;  3WN7 A;  5FNR A;  4L7B A;  3ZGD A;  3WDZ A;  2ZWA A;  2ZW9 A;  2WOZ A;  4IQK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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