3ZGCA

Crystal structure of the keap1-neh2 complex
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
285
structure length
285
Chain Sequence
GRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal-Contact Engineering to Obtain a Crystal Form of the Kelch Domain of Human Keap1 Suitable for Ligand-Soaking Experiments.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords KELCH-LIKE ECH-ASSOCIATED PROTEIN 1
total genus 65
structure length 285
sequence length 285
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-12-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 3zgcA00
3ZGDA 3WDZA 4ASCA 5CGJA 3VNGA 4ZGCA 2Z32A 1X2RA 4IN4A 1X2JA 2ZW9A 5FZJA 3ADEA 2VPJA 4L7CA 2DYHA 5FZNA 1ZGKA 5FNRA 4N1BA 5FNSA 4IFNX 4CHBA 2WOZA 5F72C 5FNQA 4ZY3A 3ZGCA 4YY8A 4XMBA 3II7A 5FNUA 4CH9A 2XN4A 5FNTA 2ZZKA 4IQKA 4IFLX 3WN7A 2FLUX 4IFJA 4L7BA 3VNHA 2ZWAA 1U6DX 4L7DA
chains in the Genus database with same CATH superfamily
4B7MA 1SLIA 1V3DA 4KS2A 1CRZA 2YDTA 1IVCA 4K1IA 4GB1A 1A14N 2ZB5A 2F24A 2IAQA 4FOQA 4FPOB 3NSSA 1CVMA 2FPBA 2SILA 5FZNA 1V0ZA 1C9UA 2BF6A 2RKCA 2QWHA 5H47A 1V3BA 1S18A 1INWA 4FJ6A 3GVLA 4X4AA 4I00A 4MWYA 3WN7A 3K38A 4KS1A 1E1AA 2VK7A 1N1TA 4XOGA 3G4EA 4XJWA 2IASA 3AMRA 2HTUA 3DR2A 4GDIA 4WEFA 5HX0A 5EO7A 1MS3A 1QLGA 2IAUA 2VK6A 4IFNX 1L7HA 5FNQA 2BATA 2F28A 1E8TA 1EURA 3O9KA 4MWLA 5GTQA 3TIBA 2AH2A 1SO7A 2B8HA 3E5ZA 1NN2A 2W8BB 3A72A 4XJAA 4MWJA 1Z50A 4IQKA 4B7QA 1IVBA 3T1EA 2FLUX 4MZAA 2XZJA 1S0JA 4GJTA 1N1VA 1NCBN 2IARA 1DIMA 4FPGA 2CMLA 5HUKA 1ZI0A 2F29A 1N1YA 4MWUA 1MWEA 4HZWA 4GNCA 5FNRA 1EUSA 5M1ZA 1RWIA 4H52A 3LI3A 4YY8A 4MC7A 4XMBA 2DG0A 4QN5A 2GVXA 1CQ1A 4WA3A 1MS0A 5HUNA 4MWQA 4D52A 5FNTA 3WW9A 1NNBA 1V0EA 4K1JA 1F8CA 5HUGA 2IAXA 4D52B 4FZHA 3TI3A 4M3MA 3NO0A 4QN3A 5HUMA 1NPEA 4FOYA 2IVZA 4YZ3A 4PWZA 4Q6KA 4YZ4A 4XILA 4FPEA 4KS3A 4B7NA 1W8OA 4XJ9A 2YA4A 2AEPA 1PJXA 2QWCA 3FVZA 5GX4A 2VW0A 1N6FA 1IUCA 4FPFA 4L7BA 3ALWA 4HZYA 5NN9A 4KS5A 1NMCA 4XJUA 1RWLA 1A4GA 1QBIA 2ZB6A 1VCJA 5GX3A 3KGGA 1E8VA 2HTRA 1W8NA 3B69A 3Q6KA 4CPOA 1W0OA 2DYHA 2XZKA 4CSDA 4N1BA 2GVWA 5GX1A 2IAWA 3AMSA 4D4UA 4K3YA 4Q1UA 2F13A 3GVKA 5D9CA 3A71A 1V3CA 5F9TA 4NN9A 4KS4A 3V1SA 2BZDA 4IYGA 1INHA 4GZSA 3LI4A 2SIMA 1EUUA 2GVVA 5EO8A 1IUBA 2VW2A 1MS9A 4XJ8A 4MWWA 2H2NA 3WWAA 4GDJA 2F25A 2HU0A 5D9DA 2QWDA 3IAXA 4HZVA 1MS4A 2POOA 1L7GA 2A75A 4MJVA 3SOVA 1H6LA 1K32A 4FPCA 4FOVA 4MX0A 2V91A 2VWDA 3O4PA 4GN8A 3Q6TA 1BJIA 3SRGA 3S94A 2VSMA 2F0ZA 3DASA 2ZWAA 2W5NA 3KYAA 3K39A 1SNTA 2QE8A 2X9MA 4ASCA 4DG6A 2VAQA 1XOEA 3TI8A 2QWIA 4IMBA 1NMAN 4XE9A 1B9VA 4D8SA 1IJQA 3TI4A 1MS5A 3ADEA 2F26A 2YDPA 4L7CA 2W5OA 4DGRA 1V2IA 3H6JA 1NNAA 1F8BA 4FPHA 4M4NA 4YW3A 4CH9A 3TI6A 3D12A 1USXA 3SOBB 3K37A 2FP9A 4YZ2A 1U6DX 1Z4XA 4AGTA 4C1YA 1E8UA 3BEQA 3HRPA 1B9SA 2QWKA 2VW1A 5FWWA 3H71A 4C1YB 5GX2A 2HTYA 3TIAA 7NN9A 4NC5A 2HU4A 1INGA 2FP8A 1KITA 4FOWA 4MZEA 5FNUA 1NSDA 4MWRA 1N6DA 3SANA 4K1KA 4UF7A 2YA7A 3TICA 4M4UA 5CGJA 3PJQA 2Z32A 4IN4A 3S8VA 1IVGA 4GZTA 4WA4A 2C4AA 4X49A 3CL0A 3CKZA 2DSOA 2HT5A 4M4VA 2IAVA 4WEGA 3P5BL 2XN4A 1C5KA 1F8EA 3OPZA 2BERA 2W20A 4CPLA 1V0FA 3TI5A 2F10A 1CRUA 4YW2A 4B7JA 3H72A 1X2RA 4HHOA 4YW4A 3A9GA 3W09A 4GZQA 1X2JA 4QN4A 4XMAA 3A9HA 4XJQA 1ZGKA 1WCSA 4QN6A 4CPMA 2DG1A 4CPNA 4GZWA 4JF7A 4HW6A 4MWVA 1Q7FA 1N6EA 2QWFA 3SILA 1XOGA 4GN7A 1W21A 4CPYA 4CPZA 4YW5A 2IAPA 1WCQA 1OFZA 3TC9A 2FPCA 1EUTA 3B7EA 2VPJA 2F12A 3I1CA 3INBA 4BBWA 4ZLRA 4FP3A 4XIKA 1SUUA 1WP5A 4H53A 1N7DA 1INVA 4YZ5A 3BYCA 3II7A 3HLHA 2QWGA 4A0PA 1B9TA 4AHAA 2HTWA 3ZGDA 1NCCN 1VCUA 3HLIA 4AH4A 2YA6A 4HHQA 3V65B 4GEZA 4HIZA 1Z4ZA 4FPLA 4MWXA 4YW1A 3G4HA 1MS1A 2QWEA 5JYYA 2IAOA 2QWJA 5FNSA 3D11A 3CYEA 2HQSA 3UC1A 3ALXA 4FPKA 3K3AA 4FPYA 3S2KA 2ZZKA 1NSCA 4XJZA 1INFA 4XHBA 4UOUA 2JKBA 2F11A 2YA5A 1W1XA 3FW0A 3SALA 3VNGA 4ZGCA 3NN9A 4GZPA 4J9TA 4XHXA 2QWAA 1INYA 1IVEA 5FZJA 3O9JA 2W8BA 3U0SA 3S8ZA 2HTQA 2SLIA 1IVFA 4GNAA 5F72C 3ZGCA 4QNPA 4ZY3A 1N1SA 4G3NA 1NMBN 1SLLA 6NN9A 4SLIA 4GZOA 4HZZA 1USRA 1V3EA 3H73A 4IFLX 3V64C 4MJUA 1POOA 1F8DA 2XCYA 4D52C 4O5TA 1DILA 1V04A 4XJRA 1W0PA 4YZ1A 1A4QA 4FPJA 3CL2A 4WA5A 4X47A 4CHBA 4AGIA 1NCAN 4FVKA 1MZ5A 2G8SA 1Z4WA 3K36A 2AEQA 2FHRA 5B2CA 4IFJA 3VNHA 5EX7A 2W38A 2IATA 1NNCA 2P4OA 2GHSA 3L6VA 4B7RA 5B2DA 1MR5A 2F27A 2ZW9A 3JU4A 1MZ6A 4XMIA 4NCSA 5GX5A 1W20A 2OJHA 2QWBA 4FP2A 1S1DA 2HTVA 2YA8A 2H2UA 4K1HA 2HT8A 4GNBA 4QN7A 1IVDA 1NCDN 1NSBA 2XZIA 3SLIA 1L7FA 4L7DA 2ISMA 3SOQA 4O5SA 5D9BA 1Z4VA 3WDZA 1INXA 4JMLA 4XIOA 2VVZA 1Z4YA 3Q6PA 4GN9A 2AGSA 4FQ4A 4HZXA 4X6KA 2WOZA 1MS8A 2VK5A 3LI5A 3SREA 3GVJA 2VSKA 4XYXA 1S0IA 2HT7A 2C4LA 4GZXA 2GVUA 4R40A
chains in the Genus database with same CATH topology
3ZGDA 3WDZA 4ASCA 5CGJA 3VNGA 4ZGCA 2Z32A 1X2RA 4IN4A 1X2JA 2ZW9A 5FZJA 3ADEA 2VPJA 4L7CA 2DYHA 5FZNA 1ZGKA 5FNRA 4N1BA 5FNSA 4IFNX 4CHBA 2WOZA 5F72C 5FNQA 4ZY3A 3ZGCA 4YY8A 4XMBA 3II7A 5FNUA 4CH9A 2XN4A 5FNTA 2ZZKA 4IQKA 4IFLX 3WN7A 2FLUX 4IFJA 4L7BA 3VNHA 2ZWAA 1U6DX 4L7DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZGD A;  3WDZ A;  4ASC A;  5CGJ A;  3VNG A;  4ZGC A;  2Z32 A;  1X2R A;  4IN4 A;  1X2J A;  2ZW9 A;  5FZJ A;  3ADE A;  2VPJ A;  4L7C A;  2DYH A;  5FZN A;  1ZGK A;  5FNR A;  4N1B A;  5FNS A;  4IFN X;  4CHB A;  2WOZ A;  5F72 C;  5FNQ A;  4ZY3 A;  3ZGC A;  4YY8 A;  4XMB A;  3II7 A;  5FNU A;  4CH9 A;  2XN4 A;  5FNT A;  2ZZK A;  4IQK A;  4IFL X;  3WN7 A;  2FLU X;  4IFJ A;  4L7B A;  3VNH A;  2ZWA A;  1U6D X;  4L7D A; 
#chains in the Genus database with same CATH topology
 4B7M A;  1SLI A;  1V3D A;  4KS2 A;  1CRZ A;  2YDT A;  1IVC A;  4K1I A;  4GB1 A;  1A14 N;  2ZB5 A;  2F24 A;  2IAQ A;  4FOQ A;  4FPO B;  3NSS A;  1CVM A;  2FPB A;  2SIL A;  5FZN A;  1V0Z A;  1C9U A;  2BF6 A;  2RKC A;  2QWH A;  5H47 A;  1V3B A;  1S18 A;  1INW A;  4FJ6 A;  3GVL A;  4X4A A;  4I00 A;  4MWY A;  3WN7 A;  3K38 A;  4KS1 A;  1E1A A;  2VK7 A;  1N1T A;  4XOG A;  3G4E A;  4XJW A;  2IAS A;  3AMR A;  2HTU A;  3DR2 A;  4GDI A;  4WEF A;  5HX0 A;  5EO7 A;  1MS3 A;  1QLG A;  2IAU A;  2VK6 A;  4IFN X;  1L7H A;  5FNQ A;  2BAT A;  2F28 A;  1E8T A;  1EUR A;  3O9K A;  4MWL A;  5GTQ A;  3TIB A;  2AH2 A;  1SO7 A;  2B8H A;  3E5Z A;  1NN2 A;  2W8B B;  3A72 A;  4XJA A;  4MWJ A;  1Z50 A;  4IQK A;  4B7Q A;  1IVB A;  3T1E A;  2FLU X;  4MZA A;  2XZJ A;  1S0J A;  4GJT A;  1N1V A;  1NCB N;  2IAR A;  1DIM A;  4FPG A;  2CML A;  5HUK A;  1ZI0 A;  2F29 A;  1N1Y A;  4MWU A;  1MWE A;  4HZW A;  4GNC A;  5FNR A;  1EUS A;  5M1Z A;  1RWI A;  4H52 A;  3LI3 A;  4YY8 A;  4MC7 A;  4XMB A;  2DG0 A;  4QN5 A;  2GVX A;  1CQ1 A;  4WA3 A;  1MS0 A;  5HUN A;  4MWQ A;  4D52 A;  5FNT A;  3WW9 A;  1NNB A;  1V0E A;  4K1J A;  1F8C A;  5HUG A;  2IAX A;  4D52 B;  4FZH A;  3TI3 A;  4M3M A;  3NO0 A;  4QN3 A;  5HUM A;  1NPE A;  4FOY A;  2IVZ A;  4YZ3 A;  4PWZ A;  4Q6K A;  4YZ4 A;  4XIL A;  4FPE A;  4KS3 A;  4B7N A;  1W8O A;  4XJ9 A;  2YA4 A;  2AEP A;  1PJX A;  2QWC A;  3FVZ A;  5GX4 A;  2VW0 A;  1N6F A;  1IUC A;  4FPF A;  4L7B A;  3ALW A;  4HZY A;  5NN9 A;  4KS5 A;  1NMC A;  4XJU A;  1RWL A;  1A4G A;  1QBI A;  2ZB6 A;  1VCJ A;  5GX3 A;  3KGG A;  1E8V A;  2HTR A;  1W8N A;  3B69 A;  3Q6K A;  4CPO A;  1W0O A;  2DYH A;  2XZK A;  4CSD A;  4N1B A;  2GVW A;  5GX1 A;  2IAW A;  3AMS A;  4D4U A;  4K3Y A;  4Q1U A;  2F13 A;  3GVK A;  5D9C A;  3A71 A;  1V3C A;  5F9T A;  4NN9 A;  4KS4 A;  3V1S A;  2BZD A;  4IYG A;  1INH A;  4GZS A;  3LI4 A;  2SIM A;  1EUU A;  2GVV A;  5EO8 A;  1IUB A;  2VW2 A;  1MS9 A;  4XJ8 A;  4MWW A;  2H2N A;  3WWA A;  4GDJ A;  2F25 A;  2HU0 A;  5D9D A;  2QWD A;  3IAX A;  4HZV A;  1MS4 A;  2POO A;  1L7G A;  2A75 A;  4MJV A;  3SOV A;  1H6L A;  1K32 A;  4FPC A;  4FOV A;  4MX0 A;  2V91 A;  2VWD A;  3O4P A;  4GN8 A;  3Q6T A;  1BJI A;  3SRG A;  3S94 A;  2VSM A;  2F0Z A;  3DAS A;  2ZWA A;  2W5N A;  3KYA A;  3K39 A;  1SNT A;  2QE8 A;  2X9M A;  4ASC A;  4DG6 A;  2VAQ A;  1XOE A;  3TI8 A;  2QWI A;  4IMB A;  1NMA N;  4XE9 A;  1B9V A;  4D8S A;  1IJQ A;  3TI4 A;  1MS5 A;  3ADE A;  2F26 A;  2YDP A;  4L7C A;  2W5O A;  4DGR A;  1V2I A;  3H6J A;  1NNA A;  1F8B A;  4FPH A;  4M4N A;  4YW3 A;  4CH9 A;  3TI6 A;  3D12 A;  1USX A;  3SOB B;  3K37 A;  2FP9 A;  4YZ2 A;  1U6D X;  1Z4X A;  4AGT A;  4C1Y A;  1E8U A;  3BEQ A;  3HRP A;  1B9S A;  2QWK A;  2VW1 A;  5FWW A;  3H71 A;  4C1Y B;  5GX2 A;  2HTY A;  3TIA A;  7NN9 A;  4NC5 A;  2HU4 A;  1ING A;  2FP8 A;  1KIT A;  4FOW A;  4MZE A;  5FNU A;  1NSD A;  4MWR A;  1N6D A;  3SAN A;  4K1K A;  4UF7 A;  2YA7 A;  3TIC A;  4M4U A;  5CGJ A;  3PJQ A;  2Z32 A;  4IN4 A;  3S8V A;  1IVG A;  4GZT A;  4WA4 A;  2C4A A;  4X49 A;  3CL0 A;  3CKZ A;  2DSO A;  2HT5 A;  4M4V A;  2IAV A;  4WEG A;  3P5B L;  2XN4 A;  1C5K A;  1F8E A;  3OPZ A;  2BER A;  2W20 A;  4CPL A;  1V0F A;  3TI5 A;  2F10 A;  1CRU A;  4YW2 A;  4B7J A;  3H72 A;  1X2R A;  4HHO A;  4YW4 A;  3A9G A;  3W09 A;  4GZQ A;  1X2J A;  4QN4 A;  4XMA A;  3A9H A;  4XJQ A;  1ZGK A;  1WCS A;  4QN6 A;  4CPM A;  2DG1 A;  4CPN A;  4GZW A;  4JF7 A;  4HW6 A;  4MWV A;  1Q7F A;  1N6E A;  2QWF A;  3SIL A;  1XOG A;  4GN7 A;  1W21 A;  4CPY A;  4CPZ A;  4YW5 A;  2IAP A;  1WCQ A;  1OFZ A;  3TC9 A;  2FPC A;  1EUT A;  3B7E A;  2VPJ A;  2F12 A;  3I1C A;  3INB A;  4BBW A;  4ZLR A;  4FP3 A;  4XIK A;  1SUU A;  1WP5 A;  4H53 A;  1N7D A;  1INV A;  4YZ5 A;  3BYC A;  3II7 A;  3HLH A;  2QWG A;  4A0P A;  1B9T A;  4AHA A;  2HTW A;  3ZGD A;  1NCC N;  1VCU A;  3HLI A;  4AH4 A;  2YA6 A;  4HHQ A;  3V65 B;  4GEZ A;  4HIZ A;  1Z4Z A;  4FPL A;  4MWX A;  4YW1 A;  3G4H A;  1MS1 A;  2QWE A;  5JYY A;  2IAO A;  2QWJ A;  5FNS A;  3D11 A;  3CYE A;  2HQS A;  3UC1 A;  3ALX A;  4FPK A;  3K3A A;  4FPY A;  3S2K A;  2ZZK A;  1NSC A;  4XJZ A;  1INF A;  4XHB A;  4UOU A;  2JKB A;  2F11 A;  2YA5 A;  1W1X A;  3FW0 A;  3SAL A;  3VNG A;  4ZGC A;  3NN9 A;  4GZP A;  4J9T A;  4XHX A;  2QWA A;  1INY A;  1IVE A;  5FZJ A;  3O9J A;  2W8B A;  3U0S A;  3S8Z A;  2HTQ A;  2SLI A;  1IVF A;  4GNA A;  5F72 C;  3ZGC A;  4QNP A;  4ZY3 A;  1N1S A;  4G3N A;  1NMB N;  1SLL A;  6NN9 A;  4SLI A;  4GZO A;  4HZZ A;  1USR A;  1V3E A;  3H73 A;  4IFL X;  3V64 C;  4MJU A;  1POO A;  1F8D A;  2XCY A;  4D52 C;  4O5T A;  1DIL A;  1V04 A;  4XJR A;  1W0P A;  4YZ1 A;  1A4Q A;  4FPJ A;  3CL2 A;  4WA5 A;  4X47 A;  4CHB A;  4AGI A;  1NCA N;  4FVK A;  1MZ5 A;  2G8S A;  1Z4W A;  3K36 A;  2AEQ A;  2FHR A;  5B2C A;  4IFJ A;  3VNH A;  5EX7 A;  2W38 A;  2IAT A;  1NNC A;  2P4O A;  2GHS A;  3L6V A;  4B7R A;  5B2D A;  1MR5 A;  2F27 A;  2ZW9 A;  3JU4 A;  1MZ6 A;  4XMI A;  4NCS A;  5GX5 A;  1W20 A;  2OJH A;  2QWB A;  4FP2 A;  1S1D A;  2HTV A;  2YA8 A;  2H2U A;  4K1H A;  2HT8 A;  4GNB A;  4QN7 A;  1IVD A;  1NCD N;  1NSB A;  2XZI A;  3SLI A;  1L7F A;  4L7D A;  2ISM A;  3SOQ A;  4O5S A;  5D9B A;  1Z4V A;  3WDZ A;  1INX A;  4JML A;  4XIO A;  2VVZ A;  1Z4Y A;  3Q6P A;  4GN9 A;  2AGS A;  4FQ4 A;  4HZX A;  4X6K A;  2WOZ A;  1MS8 A;  2VK5 A;  3LI5 A;  3SRE A;  3GVJ A;  2VSK A;  4XYX A;  1S0I A;  2HT7 A;  2C4L A;  4GZX A;  2GVU A;  4R40 A; 
#chains in the Genus database with same CATH homology
 3ZGD A;  3WDZ A;  4ASC A;  5CGJ A;  3VNG A;  4ZGC A;  2Z32 A;  1X2R A;  4IN4 A;  1X2J A;  2ZW9 A;  5FZJ A;  3ADE A;  2VPJ A;  4L7C A;  2DYH A;  5FZN A;  1ZGK A;  5FNR A;  4N1B A;  5FNS A;  4IFN X;  4CHB A;  2WOZ A;  5F72 C;  5FNQ A;  4ZY3 A;  3ZGC A;  4YY8 A;  4XMB A;  3II7 A;  5FNU A;  4CH9 A;  2XN4 A;  5FNT A;  2ZZK A;  4IQK A;  4IFL X;  3WN7 A;  2FLU X;  4IFJ A;  4L7B A;  3VNH A;  2ZWA A;  1U6D X;  4L7D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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