3ZGDA

Crystal structure of a keap1 mutant
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
285
structure length
285
Chain Sequence
GRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVATATWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal-Contact Engineering to Obtain a Crystal Form of the Kelch Domain of Human Keap1 Suitable for Ligand-Soaking Experiments.
pubmed doi rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords KELCH-LIKE ECH-ASSOCIATED PROTEIN 1
total genus 70
structure length 285
sequence length 285
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-12-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 3zgdA00
2DYHA 4ASCA 4L7DA 2FLUX 4CH9A 3ZGCA 3VNHA 5FNRA 4IFNX 3WDZA 1X2JA 1U6DX 4N1BA 2Z32A 2ZW9A 3VNGA 4ZY3A 5FNTA 3ZGDA 4CHBA 4L7BA 2XN4A 4IQKA 5F72C 4IFJA 1X2RA 5FZNA 4ZGCA 4XMBA 5FNQA 4YY8A 3II7A 3ADEA 2WOZA 5CGJA 4IN4A 2VPJA 5FNSA 4IFLX 2ZZKA 5FNUA 3WN7A 2ZWAA 5FZJA 1ZGKA 4L7CA
chains in the Genus database with same CATH superfamily
3L6VA 4B7QA 4JF7A 5D9BA 4HZYA 2ISMA 1NCAN 3SALA 4FVKA 2AEPA 4MWUA 3O9JA 4N1BA 3VNGA 1A4QA 1RWIA 5HUGA 1NCCN 5FZNA 4CPZA 4HHQA 2F29A 4FPJA 3S94A 1N6DA 2BERA 4MWJA 4CPMA 4FPKA 3KGGA 5FNSA 4J9TA 3E5ZA 2H2NA 1CRZA 1POOA 4GZOA 3H71A 3V1SA 1E8UA 4D8SA 4CPOA 3TIBA 5FNRA 4IFNX 5FWWA 1F8CA 4HZWA 1K32A 1MS4A 1N1VA 2VSMA 2VK5A 4GDJA 4FPGA 1C5KA 4KS3A 2FHRA 5F72C 1V2IA 4B7RA 2IAXA 2QWFA 3II7A 3S8VA 4MZAA 1VCUA 2GVWA 5HX0A 1INXA 1SO7A 2F28A 2ZZKA 3OPZA 3I1CA 1QBIA 2SIMA 4L7CA 3D12A 3S2KA 2YDTA 2DYHA 2IAWA 2IATA 1USXA 2GHSA 1IJQA 2JKBA 3AMSA 3WWAA 2HU0A 1A14N 2RKCA 4FQ4A 2DG0A 4MWRA 1S0JA 2F26A 1XOEA 2AGSA 2QWJA 2QWGA 4CPNA 4XJQA 4FZHA 2W8BB 3BEQA 1SNTA 4B7JA 2IAQA 4XE9A 4MWYA 4SLIA 5HUKA 1NCDN 1Z4XA 4YW3A 4XILA 1MZ6A 4YZ5A 1EURA 3LI4A 2XCYA 4K3YA 4FOYA 3WDZA 1EUSA 4M4UA 3GVLA 3TC9A 4XJRA 4AGIA 4GNBA 4XJAA 4MWWA 2A75A 2VK7A 2HTRA 4IFJA 2B8HA 1V04A 2BF6A 4YW4A 3V64C 1A4GA 2VW2A 2DG1A 4K1HA 4G3NA 5M1ZA 1V3BA 1IVEA 1W21A 5D9DA 4MWQA 2F25A 4C1YB 4ZLRA 2X9MA 3SOQA 3ZGCA 4XMIA 3A9GA 2QWEA 1S18A 3GVKA 6NN9A 1INFA 1IVGA 4YZ4A 1N6EA 2ZB5A 4O5SA 2HQSA 1IVCA 2W5NA 2HTQA 4IQKA 3ADEA 3Q6TA 1Z4WA 4M4VA 3WW9A 3G4HA 4MWLA 2VPJA 4D52A 2GVXA 4XJ9A 4NN9A 1F8BA 4XHXA 2YA6A 3JU4A 5GX5A 2QWIA 4WA4A 1MWEA 1Z50A 3LI3A 2F12A 1N7DA 1NSCA 4AHAA 4WA5A 4K1IA 5GX3A 2YA4A 3O9KA 2P4OA 2F10A 3TI3A 3DASA 4CHBA 3P5BL 2F27A 4CPYA 3K3AA 4XOGA 2W38A 3TI4A 1USRA 5EO7A 5FNUA 1Q7FA 3PJQA 4L7DA 4GN8A 2G8SA 4A0PA 2VVZA 4WA3A 1IVBA 1MS0A 2VW1A 3CL2A 5H47A 1C9UA 1F8EA 4GEZA 4DG6A 4ZGCA 2C4AA 1E1AA 2F0ZA 1MS9A 4B7MA 4D52C 1N6FA 3H72A 1INWA 1WP5A 3AMRA 3HLHA 4FP2A 4IYGA 2HTYA 4FPFA 2HTUA 2ZWAA 2FPCA 1XOGA 3UC1A 1OFZA 3U0SA 4ASCA 2YA8A 4QN4A 1V3EA 2VK6A 4X6KA 4X49A 2SILA 1V0FA 1E8TA 3HLIA 3A71A 4XYXA 1U6DX 2XZKA 5GX4A 2XZJA 2H2UA 2QWDA 2HTVA 4L7BA 1WCQA 2QWBA 3TI5A 4NCSA 1V3CA 1IVFA 4MJVA 5CGJA 7NN9A 1NNBA 4KS2A 4MZEA 4GZTA 5FZJA 2QWAA 3CL0A 2AEQA 2IAPA 4JMLA 4UF7A 3V65B 3W09A 4FOWA 2GVVA 1NMCA 4HZVA 5EO8A 4XJ8A 5HUNA 4B7NA 4H52A 1INVA 1N1TA 2F24A 2FP9A 3CKZA 1Z4YA 2CMLA 4R40A 3Q6PA 1L7FA 3D11A 2FPBA 1NSBA 2HT7A 3KYAA 4GZPA 2VSKA 4AGTA 5GX2A 1NPEA 3H73A 1NMBN 5B2DA 4I00A 3IAXA 1CRUA 1E8VA 3K36A 4PWZA 4MWVA 1DILA 1INYA 2VWDA 4FPCA 1ZI0A 2YA5A 5NN9A 1W0OA 1W8OA 2SLIA 4FPOB 3TI8A 1IUBA 1V0ZA 3K38A 4IN4A 3SANA 4GZWA 4YW1A 4M3MA 5GX1A 1ZGKA 4HZXA 4CSDA 2YDPA 3FW0A 3LI5A 4XHBA 3NSSA 3VNHA 4CPLA 1CQ1A 2XZIA 1MR5A 5D9CA 3TIAA 2W8BA 1PJXA 1WCSA 4QN3A 2IAVA 4WEFA 3BYCA 2BATA 2IASA 1MS5A 1F8DA 4IMBA 3GVJA 4FPEA 2DSOA 3S8ZA 2QE8A 3INBA 1INHA 1B9VA 3H6JA 1IUCA 3FVZA 1NNCA 2F13A 4YZ3A 4HIZA 4KS5A 2ZB6A 4QN5A 4D4UA 1N1SA 3G4EA 4Q1UA 1SLIA 2POOA 3HRPA 1B9TA 4CH9A 2V91A 4UOUA 4FOQA 4GZQA 4KS1A 1NNAA 4QN6A 1L7HA 4O5TA 4YZ1A 4ZY3A 2FP8A 4FPYA 1MZ5A 4MJUA 4K1JA 1X2RA 4GN7A 4XMBA 4H53A 5FNQA 2VAQA 3NO0A 4YY8A 4YW5A 3T1EA 4C1YA 2HTWA 3K37A 4XMAA 2VW0A 1H6LA 2IAOA 1W20A 3B69A 4GNAA 2FLUX 4HHOA 1X2JA 1VCJA 3A9HA 3K39A 4FP3A 3A72A 4YW2A 4KS4A 3SOVA 1N1YA 4FPLA 2QWHA 4QNPA 3B7EA 1SLLA 2OJHA 2W5OA 4M4NA 4IFLX 3TICA 3ALWA 1MS8A 4GZXA 1EUTA 1NSDA 4D52B 3O4PA 4X4AA 1INGA 1NCBN 4GJTA 1L7GA 1MS1A 5GTQA 5EX7A 3ALXA 4GB1A 4MX0A 1EUUA 2Z32A 3SOBB 5FNTA 4MC7A 4YZ2A 2QWKA 4WEGA 3SILA 1QLGA 2WOZA 1RWLA 4Q6KA 3SLIA 2IAUA 4XJWA 4XJUA 3WN7A 4QN7A 1NN2A 4DGRA 4HZZA 1S1DA 4GDIA 2YA7A 2F11A 1DIMA 5F9TA 1MS3A 2HT5A 1V0EA 3SRGA 2IARA 2ZW9A 1V3DA 2GVUA 4FPHA 2C4LA 4FJ6A 3CYEA 2W20A 1NMAN 4GNCA 4X47A 1SUUA 4BBWA 1KITA 1CVMA 3DR2A 4HW6A 4XIKA 1W0PA 4AH4A 4K1KA 4FOVA 2HU4A 1Z4VA 2IVZA 2BZDA 2QWCA 3Q6KA 3ZGDA 1BJIA 1S0IA 2XN4A 4GN9A 2HT8A 4GZSA 2AH2A 5JYYA 1Z4ZA 4NC5A 1W1XA 3NN9A 3TI6A 1B9SA 1W8NA 5HUMA 1IVDA 4XIOA 4XJZA 5B2CA 3SREA 4MWXA
chains in the Genus database with same CATH topology
2DYHA 4ASCA 4L7DA 2FLUX 4CH9A 3ZGCA 3VNHA 5FNRA 4IFNX 3WDZA 1X2JA 1U6DX 4N1BA 2Z32A 2ZW9A 3VNGA 4ZY3A 5FNTA 3ZGDA 4CHBA 4L7BA 2XN4A 4IQKA 5F72C 4IFJA 1X2RA 5FZNA 4ZGCA 4XMBA 5FNQA 4YY8A 3II7A 3ADEA 2WOZA 5CGJA 4IN4A 2VPJA 5FNSA 4IFLX 2ZZKA 5FNUA 3WN7A 2ZWAA 5FZJA 1ZGKA 4L7CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DYH A;  4ASC A;  4L7D A;  2FLU X;  4CH9 A;  3ZGC A;  3VNH A;  5FNR A;  4IFN X;  3WDZ A;  1X2J A;  1U6D X;  4N1B A;  2Z32 A;  2ZW9 A;  3VNG A;  4ZY3 A;  5FNT A;  3ZGD A;  4CHB A;  4L7B A;  2XN4 A;  4IQK A;  5F72 C;  4IFJ A;  1X2R A;  5FZN A;  4ZGC A;  4XMB A;  5FNQ A;  4YY8 A;  3II7 A;  3ADE A;  2WOZ A;  5CGJ A;  4IN4 A;  2VPJ A;  5FNS A;  4IFL X;  2ZZK A;  5FNU A;  3WN7 A;  2ZWA A;  5FZJ A;  1ZGK A;  4L7C A; 
#chains in the Genus database with same CATH topology
 3L6V A;  4B7Q A;  4JF7 A;  5D9B A;  4HZY A;  2ISM A;  1NCA N;  3SAL A;  4FVK A;  2AEP A;  4MWU A;  3O9J A;  4N1B A;  3VNG A;  1A4Q A;  1RWI A;  5HUG A;  1NCC N;  5FZN A;  4CPZ A;  4HHQ A;  2F29 A;  4FPJ A;  3S94 A;  1N6D A;  2BER A;  4MWJ A;  4CPM A;  4FPK A;  3KGG A;  5FNS A;  4J9T A;  3E5Z A;  2H2N A;  1CRZ A;  1POO A;  4GZO A;  3H71 A;  3V1S A;  1E8U A;  4D8S A;  4CPO A;  3TIB A;  5FNR A;  4IFN X;  5FWW A;  1F8C A;  4HZW A;  1K32 A;  1MS4 A;  1N1V A;  2VSM A;  2VK5 A;  4GDJ A;  4FPG A;  1C5K A;  4KS3 A;  2FHR A;  5F72 C;  1V2I A;  4B7R A;  2IAX A;  2QWF A;  3II7 A;  3S8V A;  4MZA A;  1VCU A;  2GVW A;  5HX0 A;  1INX A;  1SO7 A;  2F28 A;  2ZZK A;  3OPZ A;  3I1C A;  1QBI A;  2SIM A;  4L7C A;  3D12 A;  3S2K A;  2YDT A;  2DYH A;  2IAW A;  2IAT A;  1USX A;  2GHS A;  1IJQ A;  2JKB A;  3AMS A;  3WWA A;  2HU0 A;  1A14 N;  2RKC A;  4FQ4 A;  2DG0 A;  4MWR A;  1S0J A;  2F26 A;  1XOE A;  2AGS A;  2QWJ A;  2QWG A;  4CPN A;  4XJQ A;  4FZH A;  2W8B B;  3BEQ A;  1SNT A;  4B7J A;  2IAQ A;  4XE9 A;  4MWY A;  4SLI A;  5HUK A;  1NCD N;  1Z4X A;  4YW3 A;  4XIL A;  1MZ6 A;  4YZ5 A;  1EUR A;  3LI4 A;  2XCY A;  4K3Y A;  4FOY A;  3WDZ A;  1EUS A;  4M4U A;  3GVL A;  3TC9 A;  4XJR A;  4AGI A;  4GNB A;  4XJA A;  4MWW A;  2A75 A;  2VK7 A;  2HTR A;  4IFJ A;  2B8H A;  1V04 A;  2BF6 A;  4YW4 A;  3V64 C;  1A4G A;  2VW2 A;  2DG1 A;  4K1H A;  4G3N A;  5M1Z A;  1V3B A;  1IVE A;  1W21 A;  5D9D A;  4MWQ A;  2F25 A;  4C1Y B;  4ZLR A;  2X9M A;  3SOQ A;  3ZGC A;  4XMI A;  3A9G A;  2QWE A;  1S18 A;  3GVK A;  6NN9 A;  1INF A;  1IVG A;  4YZ4 A;  1N6E A;  2ZB5 A;  4O5S A;  2HQS A;  1IVC A;  2W5N A;  2HTQ A;  4IQK A;  3ADE A;  3Q6T A;  1Z4W A;  4M4V A;  3WW9 A;  3G4H A;  4MWL A;  2VPJ A;  4D52 A;  2GVX A;  4XJ9 A;  4NN9 A;  1F8B A;  4XHX A;  2YA6 A;  3JU4 A;  5GX5 A;  2QWI A;  4WA4 A;  1MWE A;  1Z50 A;  3LI3 A;  2F12 A;  1N7D A;  1NSC A;  4AHA A;  4WA5 A;  4K1I A;  5GX3 A;  2YA4 A;  3O9K A;  2P4O A;  2F10 A;  3TI3 A;  3DAS A;  4CHB A;  3P5B L;  2F27 A;  4CPY A;  3K3A A;  4XOG A;  2W38 A;  3TI4 A;  1USR A;  5EO7 A;  5FNU A;  1Q7F A;  3PJQ A;  4L7D A;  4GN8 A;  2G8S A;  4A0P A;  2VVZ A;  4WA3 A;  1IVB A;  1MS0 A;  2VW1 A;  3CL2 A;  5H47 A;  1C9U A;  1F8E A;  4GEZ A;  4DG6 A;  4ZGC A;  2C4A A;  1E1A A;  2F0Z A;  1MS9 A;  4B7M A;  4D52 C;  1N6F A;  3H72 A;  1INW A;  1WP5 A;  3AMR A;  3HLH A;  4FP2 A;  4IYG A;  2HTY A;  4FPF A;  2HTU A;  2ZWA A;  2FPC A;  1XOG A;  3UC1 A;  1OFZ A;  3U0S A;  4ASC A;  2YA8 A;  4QN4 A;  1V3E A;  2VK6 A;  4X6K A;  4X49 A;  2SIL A;  1V0F A;  1E8T A;  3HLI A;  3A71 A;  4XYX A;  1U6D X;  2XZK A;  5GX4 A;  2XZJ A;  2H2U A;  2QWD A;  2HTV A;  4L7B A;  1WCQ A;  2QWB A;  3TI5 A;  4NCS A;  1V3C A;  1IVF A;  4MJV A;  5CGJ A;  7NN9 A;  1NNB A;  4KS2 A;  4MZE A;  4GZT A;  5FZJ A;  2QWA A;  3CL0 A;  2AEQ A;  2IAP A;  4JML A;  4UF7 A;  3V65 B;  3W09 A;  4FOW A;  2GVV A;  1NMC A;  4HZV A;  5EO8 A;  4XJ8 A;  5HUN A;  4B7N A;  4H52 A;  1INV A;  1N1T A;  2F24 A;  2FP9 A;  3CKZ A;  1Z4Y A;  2CML A;  4R40 A;  3Q6P A;  1L7F A;  3D11 A;  2FPB A;  1NSB A;  2HT7 A;  3KYA A;  4GZP A;  2VSK A;  4AGT A;  5GX2 A;  1NPE A;  3H73 A;  1NMB N;  5B2D A;  4I00 A;  3IAX A;  1CRU A;  1E8V A;  3K36 A;  4PWZ A;  4MWV A;  1DIL A;  1INY A;  2VWD A;  4FPC A;  1ZI0 A;  2YA5 A;  5NN9 A;  1W0O A;  1W8O A;  2SLI A;  4FPO B;  3TI8 A;  1IUB A;  1V0Z A;  3K38 A;  4IN4 A;  3SAN A;  4GZW A;  4YW1 A;  4M3M A;  5GX1 A;  1ZGK A;  4HZX A;  4CSD A;  2YDP A;  3FW0 A;  3LI5 A;  4XHB A;  3NSS A;  3VNH A;  4CPL A;  1CQ1 A;  2XZI A;  1MR5 A;  5D9C A;  3TIA A;  2W8B A;  1PJX A;  1WCS A;  4QN3 A;  2IAV A;  4WEF A;  3BYC A;  2BAT A;  2IAS A;  1MS5 A;  1F8D A;  4IMB A;  3GVJ A;  4FPE A;  2DSO A;  3S8Z A;  2QE8 A;  3INB A;  1INH A;  1B9V A;  3H6J A;  1IUC A;  3FVZ A;  1NNC A;  2F13 A;  4YZ3 A;  4HIZ A;  4KS5 A;  2ZB6 A;  4QN5 A;  4D4U A;  1N1S A;  3G4E A;  4Q1U A;  1SLI A;  2POO A;  3HRP A;  1B9T A;  4CH9 A;  2V91 A;  4UOU A;  4FOQ A;  4GZQ A;  4KS1 A;  1NNA A;  4QN6 A;  1L7H A;  4O5T A;  4YZ1 A;  4ZY3 A;  2FP8 A;  4FPY A;  1MZ5 A;  4MJU A;  4K1J A;  1X2R A;  4GN7 A;  4XMB A;  4H53 A;  5FNQ A;  2VAQ A;  3NO0 A;  4YY8 A;  4YW5 A;  3T1E A;  4C1Y A;  2HTW A;  3K37 A;  4XMA A;  2VW0 A;  1H6L A;  2IAO A;  1W20 A;  3B69 A;  4GNA A;  2FLU X;  4HHO A;  1X2J A;  1VCJ A;  3A9H A;  3K39 A;  4FP3 A;  3A72 A;  4YW2 A;  4KS4 A;  3SOV A;  1N1Y A;  4FPL A;  2QWH A;  4QNP A;  3B7E A;  1SLL A;  2OJH A;  2W5O A;  4M4N A;  4IFL X;  3TIC A;  3ALW A;  1MS8 A;  4GZX A;  1EUT A;  1NSD A;  4D52 B;  3O4P A;  4X4A A;  1ING A;  1NCB N;  4GJT A;  1L7G A;  1MS1 A;  5GTQ A;  5EX7 A;  3ALX A;  4GB1 A;  4MX0 A;  1EUU A;  2Z32 A;  3SOB B;  5FNT A;  4MC7 A;  4YZ2 A;  2QWK A;  4WEG A;  3SIL A;  1QLG A;  2WOZ A;  1RWL A;  4Q6K A;  3SLI A;  2IAU A;  4XJW A;  4XJU A;  3WN7 A;  4QN7 A;  1NN2 A;  4DGR A;  4HZZ A;  1S1D A;  4GDI A;  2YA7 A;  2F11 A;  1DIM A;  5F9T A;  1MS3 A;  2HT5 A;  1V0E A;  3SRG A;  2IAR A;  2ZW9 A;  1V3D A;  2GVU A;  4FPH A;  2C4L A;  4FJ6 A;  3CYE A;  2W20 A;  1NMA N;  4GNC A;  4X47 A;  1SUU A;  4BBW A;  1KIT A;  1CVM A;  3DR2 A;  4HW6 A;  4XIK A;  1W0P A;  4AH4 A;  4K1K A;  4FOV A;  2HU4 A;  1Z4V A;  2IVZ A;  2BZD A;  2QWC A;  3Q6K A;  3ZGD A;  1BJI A;  1S0I A;  2XN4 A;  4GN9 A;  2HT8 A;  4GZS A;  2AH2 A;  5JYY A;  1Z4Z A;  4NC5 A;  1W1X A;  3NN9 A;  3TI6 A;  1B9S A;  1W8N A;  5HUM A;  1IVD A;  4XIO A;  4XJZ A;  5B2C A;  3SRE A;  4MWX A; 
#chains in the Genus database with same CATH homology
 2DYH A;  4ASC A;  4L7D A;  2FLU X;  4CH9 A;  3ZGC A;  3VNH A;  5FNR A;  4IFN X;  3WDZ A;  1X2J A;  1U6D X;  4N1B A;  2Z32 A;  2ZW9 A;  3VNG A;  4ZY3 A;  5FNT A;  3ZGD A;  4CHB A;  4L7B A;  2XN4 A;  4IQK A;  5F72 C;  4IFJ A;  1X2R A;  5FZN A;  4ZGC A;  4XMB A;  5FNQ A;  4YY8 A;  3II7 A;  3ADE A;  2WOZ A;  5CGJ A;  4IN4 A;  2VPJ A;  5FNS A;  4IFL X;  2ZZK A;  5FNU A;  3WN7 A;  2ZWA A;  5FZJ A;  1ZGK A;  4L7C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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