4D52C

Crystal structure of fucose binding lectin from aspergillus fumigatus (afl) in complex with l-galactopyranose.
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
314
structure length
310
Chain Sequence
STPGAQQVLFRTGIAAVNSTNHLRVYFQDVYGSIRESLYEGSWANGTEKNVIGNAKLGSPVAATSKELKHIRVYTLTEGNTLQEFAYDSGTGWYNGGLGGAKFQVAPYSIAAVFLAGTDALQLRIYAQKPDNTIQEYMWNGDGWKEGTNLGGALPGTGIGATSFRYTDYNGPSIRIWFQTDDLKLVQRAYDPHKGWYPDLVTIFDRAPPRTAIAATSFGAGNSSIYMRIYFVNSDNTIWQVWDHGKGYHDKGTITPVIQGSEVAIISWGSFNGPDLRLYFQNGTYISAVSEWVWNRAHGSQLGRSALPPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Aspergillus Fumigatus Lectin Specificity: Afl Binding Sites are Functionally Non-Equivalent.
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Aspergillus fumigatus
molecule keywords FUCOSE-SPECIFIC LECTIN FLEA
total genus 79
structure length 310
sequence length 314
ec nomenclature
pdb deposition date 2014-11-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF07938 Fungal_lectin Fungal fucose-specific lectin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.70 Mainly Beta 6 Propeller Neuraminidase Fucose-specific lectin 4d52C00
4C1YB 4D52B 1IUCA 4UOUA 1IUBA 4D52C 4C1YA 5EO8A 5EO7A 4AGIA 4AH4A 4CSDA 4D52A 4D4UA 1OFZA 5H47A 4AGTA 4AHAA
chains in the Genus database with same CATH superfamily
1B9VA 4QN4A 1VCUA 3E5ZA 5FNQA 3S94A 2FPCA 1USXA 1W0PA 5GX1A 4FZHA 4IYGA 1EUUA 3CL0A 4KS3A 4XJQA 1XOEA 1POOA 1A14N 1NCBN 4FPGA 1B9SA 1MS1A 2Z32A 2F27A 2BERA 4IN4A 5EO7A 2IATA 3K39A 1PJXA 4WA5A 2VPJA 1W1XA 2VK7A 3GVLA 1F8BA 4XJUA 1V0EA 1Z50A 2QWHA 1IUCA 2YA4A 2AGSA 2IARA 3SOQA 3Q6TA 4FOQA 1V3DA 4XJRA 4YW3A 1X2JA 2HT7A 4HZZA 3Q6KA 4K1JA 2VW2A 4M4VA 4D52B 2FHRA 3S8ZA 1MR5A 4HZXA 4XILA 5H47A 2QWCA 2HTWA 4YW1A 3OPZA 5GX3A 4GDJA 4X49A 5FZNA 4YW4A 5D9DA 4M4NA 4YZ4A 1KITA 3TICA 1N1TA 5M1ZA 3AMSA 4XJWA 3U0SA 4XJ9A 2F28A 3WN7A 1DILA 4HIZA 2SLIA 1Z4ZA 4GZQA 5HUKA 4K3YA 4MWVA 4AH4A 2QE8A 4GNAA 1V2IA 2SILA 1SLIA 3NO0A 4WEGA 3II7A 4FPLA 4HZVA 2VSMA 3S8VA 4FP3A 4GZPA 4GN9A 1N7DA 5JYYA 4ZGCA 1N6DA 3SANA 2H2NA 2AEPA 4MWXA 4DGRA 7NN9A 5GX2A 1B9TA 2VAQA 1VCJA 4J9TA 4D52A 4CH9A 4KS4A 4XE9A 4MC7A 4IFJA 2VSKA 2QWAA 1INHA 4YZ5A 5GX4A 1NNCA 1IVDA 4YY8A 4B7JA 1MS4A 4MJUA 4PWZA 5EX7A 1W8OA 4FP2A 3LI5A 2YA6A 1E1AA 4KS2A 1F8DA 4YZ1A 4MZEA 2BATA 1NCCN 1S18A 4WA3A 4X6KA 5F9TA 5FNRA 5D9BA 4GEZA 1V3CA 3VNHA 4UOUA 4MWLA 4H52A 1MS8A 5HUMA 1S0JA 1N1VA 2OJHA 3Q6PA 1W20A 3NN9A 1MS0A 2VVZA 4C1YA 1F8EA 1CVMA 2HT5A 4NN9A 2F11A 3V1SA 3W09A 5FWWA 2YDTA 2HTRA 2VW0A 3D11A 2HU0A 4GZOA 2AH2A 4K1IA 4XMIA 5CGJA 4XIKA 1Z4VA 1Z4WA 2H2UA 3ALXA 3HRPA 3B69A 4FOYA 4MWJA 4MJVA 1DIMA 5NN9A 2YA5A 4CPLA 4K1HA 2IVZA 5GX5A 1EUTA 4MWRA 2FP9A 2HT8A 3P5BL 1NMAN 3B7EA 4CPYA 4X4AA 2W5NA 1NNBA 2GVVA 4XYXA 4FPKA 2DG1A 4GDIA 1N6EA 1MZ6A 4L7CA 4MWWA 4GJTA 1INXA 4FPEA 2QWIA 2ZWAA 1NMCA 5F72C 1C5KA 2X9MA 4NC5A 2IAPA 4CSDA 4GZSA 3INBA 2F24A 1Q7FA 2IAOA 2SIMA 2IASA 1INVA 3CL2A 2XCYA 3K37A 1IVGA 1NCDN 3O4PA 5FZJA 2GVWA 3TI5A 4Q6KA 1IVCA 2HTUA 4FOVA 1CQ1A 1NSCA 4L7BA 1ZGKA 2FLUX 2YDPA 2QWBA 4ASCA 2IAVA 4QN3A 2W8BB 2GVUA 3A71A 3H73A 4AGTA 3O9KA 1EURA 3TI3A 4A0PA 3H6JA 4XIOA 1L7HA 3O9JA 2CMLA 4C1YB 1A4QA 4ZLRA 2POOA 6NN9A 2DSOA 3SREA 3L6VA 4CPZA 2W38A 4IMBA 3TI8A 4CHBA 1H6LA 1MS9A 2GVXA 4IFNX 4FJ6A 2DYHA 3DASA 3HLHA 4B7NA 1EUSA 1SUUA 1QLGA 4QN5A 2F10A 1E8UA 1NNAA 4X47A 4FPCA 4ZY3A 2W5OA 4MWQA 1IVFA 1RWLA 2A75A 4D8SA 2HTVA 2ISMA 4XMBA 2G8SA 2W8BA 2GHSA 2XN4A 4MWYA 4XHXA 1MZ5A 2QWFA 1S0IA 3G4EA 4JF7A 4QNPA 2V91A 4M3MA 5HUNA 4KS1A 3SLIA 2QWDA 1CRZA 1WCSA 1N6FA 4FPYA 2YA7A 4MWUA 1BJIA 4K1KA 1INGA 1U6DX 5GTQA 3IAXA 4WA4A 4DG6A 2FPBA 3A9GA 2QWJA 3LI3A 5HUGA 4XJZA 3ZGDA 1N1SA 1V04A 2IAUA 1MS3A 4GN7A 2W20A 4B7RA 2QWEA 4JMLA 3I1CA 2ZW9A 4GB1A 3UC1A 2HTYA 1NSDA 4CPNA 4XJ8A 1INYA 5B2CA 1SO7A 3DR2A 1A4GA 4HHQA 4KS5A 4BBWA 2F29A 1V3BA 4GZXA 2YA8A 2RKCA 4L7DA 4B7QA 2JKBA 3S2KA 2VWDA 4AGIA 3LI4A 2C4LA 4SLIA 5FNSA 2QWGA 4QN7A 3WDZA 3K3AA 1WP5A 5FNUA 4GZTA 3SALA 3A72A 3BEQA 2IAWA 4WEFA 1NSBA 2XZIA 2ZB5A 4O5SA 1USRA 3A9HA 3D12A 3TC9A 2BZDA 3TI6A 2VK5A 1F8CA 1CRUA 3AMRA 3H72A 1IVBA 2P4OA 3SRGA 2BF6A 3WWAA 4I00A 4R40A 4FQ4A 4MZAA 3H71A 4HZYA 2HTQA 5B2DA 4FPJA 1X2RA 3K38A 1IJQA 1K32A 1OFZA 4HZWA 4FPOB 3SOBB 4GZWA 1L7FA 4QN6A 4UF7A 4GNCA 1NCAN 1W21A 2F12A 4AHAA 5D9CA 3KGGA 1INFA 2VK6A 3JU4A 4CPOA 1MS5A 2IAQA 3WW9A 2VW1A 3FVZA 1IVEA 4XOGA 4NCSA 4D52C 3VNGA 4HW6A 1RWIA 2F0ZA 3G4HA 5EO8A 4FPHA 2B8HA 1V0FA 3SILA 4YW5A 1V0ZA 3GVJA 1W8NA 1SLLA 1ZI0A 3TIAA 3GVKA 1WCQA 2F26A 2QWKA 4IFLX 2F13A 1C9UA 4D4UA 4HHOA 4Q1UA 2C4AA 1Z4XA 3SOVA 4N1BA 1E8VA 2F25A 2XZKA 1XOGA 1QBIA 4GN8A 4M4UA 4FVKA 4CPMA 4FOWA 4YZ2A 4YZ3A 1NPEA 3CKZA 1N1YA 3V65B 4B7MA 3ALWA 2IAXA 3ZGCA 4XHBA 3NSSA 2HQSA 1V3EA 3ADEA 1S1DA 4O5TA 2ZZKA 3CYEA 1MWEA 1NN2A 1INWA 5HX0A 4IQKA 3V64C 4XJAA 4GNBA 3HLIA 2FP8A 1W0OA 2DG0A 4XMAA 4H53A 2XZJA 1NMBN 3BYCA 4YW2A 4FPFA 4G3NA 1IUBA 1Z4YA 3KYAA 3PJQA 2WOZA 1SNTA 3T1EA 3TIBA 2HU4A 4MX0A 2AEQA 2ZB6A 3TI4A 1L7GA 1E8TA 3K36A 5FNTA 3FW0A
chains in the Genus database with same CATH topology
4C1YB 4D52B 1IUCA 4UOUA 1IUBA 4D52C 4C1YA 5EO8A 5EO7A 4AGIA 4AH4A 4CSDA 4D52A 4D4UA 1OFZA 5H47A 4AGTA 4AHAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4C1Y B;  4D52 B;  1IUC A;  4UOU A;  1IUB A;  4D52 C;  4C1Y A;  5EO8 A;  5EO7 A;  4AGI A;  4AH4 A;  4CSD A;  4D52 A;  4D4U A;  1OFZ A;  5H47 A;  4AGT A;  4AHA A; 
#chains in the Genus database with same CATH topology
 1B9V A;  4QN4 A;  1VCU A;  3E5Z A;  5FNQ A;  3S94 A;  2FPC A;  1USX A;  1W0P A;  5GX1 A;  4FZH A;  4IYG A;  1EUU A;  3CL0 A;  4KS3 A;  4XJQ A;  1XOE A;  1POO A;  1A14 N;  1NCB N;  4FPG A;  1B9S A;  1MS1 A;  2Z32 A;  2F27 A;  2BER A;  4IN4 A;  5EO7 A;  2IAT A;  3K39 A;  1PJX A;  4WA5 A;  2VPJ A;  1W1X A;  2VK7 A;  3GVL A;  1F8B A;  4XJU A;  1V0E A;  1Z50 A;  2QWH A;  1IUC A;  2YA4 A;  2AGS A;  2IAR A;  3SOQ A;  3Q6T A;  4FOQ A;  1V3D A;  4XJR A;  4YW3 A;  1X2J A;  2HT7 A;  4HZZ A;  3Q6K A;  4K1J A;  2VW2 A;  4M4V A;  4D52 B;  2FHR A;  3S8Z A;  1MR5 A;  4HZX A;  4XIL A;  5H47 A;  2QWC A;  2HTW A;  4YW1 A;  3OPZ A;  5GX3 A;  4GDJ A;  4X49 A;  5FZN A;  4YW4 A;  5D9D A;  4M4N A;  4YZ4 A;  1KIT A;  3TIC A;  1N1T A;  5M1Z A;  3AMS A;  4XJW A;  3U0S A;  4XJ9 A;  2F28 A;  3WN7 A;  1DIL A;  4HIZ A;  2SLI A;  1Z4Z A;  4GZQ A;  5HUK A;  4K3Y A;  4MWV A;  4AH4 A;  2QE8 A;  4GNA A;  1V2I A;  2SIL A;  1SLI A;  3NO0 A;  4WEG A;  3II7 A;  4FPL A;  4HZV A;  2VSM A;  3S8V A;  4FP3 A;  4GZP A;  4GN9 A;  1N7D A;  5JYY A;  4ZGC A;  1N6D A;  3SAN A;  2H2N A;  2AEP A;  4MWX A;  4DGR A;  7NN9 A;  5GX2 A;  1B9T A;  2VAQ A;  1VCJ A;  4J9T A;  4D52 A;  4CH9 A;  4KS4 A;  4XE9 A;  4MC7 A;  4IFJ A;  2VSK A;  2QWA A;  1INH A;  4YZ5 A;  5GX4 A;  1NNC A;  1IVD A;  4YY8 A;  4B7J A;  1MS4 A;  4MJU A;  4PWZ A;  5EX7 A;  1W8O A;  4FP2 A;  3LI5 A;  2YA6 A;  1E1A A;  4KS2 A;  1F8D A;  4YZ1 A;  4MZE A;  2BAT A;  1NCC N;  1S18 A;  4WA3 A;  4X6K A;  5F9T A;  5FNR A;  5D9B A;  4GEZ A;  1V3C A;  3VNH A;  4UOU A;  4MWL A;  4H52 A;  1MS8 A;  5HUM A;  1S0J A;  1N1V A;  2OJH A;  3Q6P A;  1W20 A;  3NN9 A;  1MS0 A;  2VVZ A;  4C1Y A;  1F8E A;  1CVM A;  2HT5 A;  4NN9 A;  2F11 A;  3V1S A;  3W09 A;  5FWW A;  2YDT A;  2HTR A;  2VW0 A;  3D11 A;  2HU0 A;  4GZO A;  2AH2 A;  4K1I A;  4XMI A;  5CGJ A;  4XIK A;  1Z4V A;  1Z4W A;  2H2U A;  3ALX A;  3HRP A;  3B69 A;  4FOY A;  4MWJ A;  4MJV A;  1DIM A;  5NN9 A;  2YA5 A;  4CPL A;  4K1H A;  2IVZ A;  5GX5 A;  1EUT A;  4MWR A;  2FP9 A;  2HT8 A;  3P5B L;  1NMA N;  3B7E A;  4CPY A;  4X4A A;  2W5N A;  1NNB A;  2GVV A;  4XYX A;  4FPK A;  2DG1 A;  4GDI A;  1N6E A;  1MZ6 A;  4L7C A;  4MWW A;  4GJT A;  1INX A;  4FPE A;  2QWI A;  2ZWA A;  1NMC A;  5F72 C;  1C5K A;  2X9M A;  4NC5 A;  2IAP A;  4CSD A;  4GZS A;  3INB A;  2F24 A;  1Q7F A;  2IAO A;  2SIM A;  2IAS A;  1INV A;  3CL2 A;  2XCY A;  3K37 A;  1IVG A;  1NCD N;  3O4P A;  5FZJ A;  2GVW A;  3TI5 A;  4Q6K A;  1IVC A;  2HTU A;  4FOV A;  1CQ1 A;  1NSC A;  4L7B A;  1ZGK A;  2FLU X;  2YDP A;  2QWB A;  4ASC A;  2IAV A;  4QN3 A;  2W8B B;  2GVU A;  3A71 A;  3H73 A;  4AGT A;  3O9K A;  1EUR A;  3TI3 A;  4A0P A;  3H6J A;  4XIO A;  1L7H A;  3O9J A;  2CML A;  4C1Y B;  1A4Q A;  4ZLR A;  2POO A;  6NN9 A;  2DSO A;  3SRE A;  3L6V A;  4CPZ A;  2W38 A;  4IMB A;  3TI8 A;  4CHB A;  1H6L A;  1MS9 A;  2GVX A;  4IFN X;  4FJ6 A;  2DYH A;  3DAS A;  3HLH A;  4B7N A;  1EUS A;  1SUU A;  1QLG A;  4QN5 A;  2F10 A;  1E8U A;  1NNA A;  4X47 A;  4FPC A;  4ZY3 A;  2W5O A;  4MWQ A;  1IVF A;  1RWL A;  2A75 A;  4D8S A;  2HTV A;  2ISM A;  4XMB A;  2G8S A;  2W8B A;  2GHS A;  2XN4 A;  4MWY A;  4XHX A;  1MZ5 A;  2QWF A;  1S0I A;  3G4E A;  4JF7 A;  4QNP A;  2V91 A;  4M3M A;  5HUN A;  4KS1 A;  3SLI A;  2QWD A;  1CRZ A;  1WCS A;  1N6F A;  4FPY A;  2YA7 A;  4MWU A;  1BJI A;  4K1K A;  1ING A;  1U6D X;  5GTQ A;  3IAX A;  4WA4 A;  4DG6 A;  2FPB A;  3A9G A;  2QWJ A;  3LI3 A;  5HUG A;  4XJZ A;  3ZGD A;  1N1S A;  1V04 A;  2IAU A;  1MS3 A;  4GN7 A;  2W20 A;  4B7R A;  2QWE A;  4JML A;  3I1C A;  2ZW9 A;  4GB1 A;  3UC1 A;  2HTY A;  1NSD A;  4CPN A;  4XJ8 A;  1INY A;  5B2C A;  1SO7 A;  3DR2 A;  1A4G A;  4HHQ A;  4KS5 A;  4BBW A;  2F29 A;  1V3B A;  4GZX A;  2YA8 A;  2RKC A;  4L7D A;  4B7Q A;  2JKB A;  3S2K A;  2VWD A;  4AGI A;  3LI4 A;  2C4L A;  4SLI A;  5FNS A;  2QWG A;  4QN7 A;  3WDZ A;  3K3A A;  1WP5 A;  5FNU A;  4GZT A;  3SAL A;  3A72 A;  3BEQ A;  2IAW A;  4WEF A;  1NSB A;  2XZI A;  2ZB5 A;  4O5S A;  1USR A;  3A9H A;  3D12 A;  3TC9 A;  2BZD A;  3TI6 A;  2VK5 A;  1F8C A;  1CRU A;  3AMR A;  3H72 A;  1IVB A;  2P4O A;  3SRG A;  2BF6 A;  3WWA A;  4I00 A;  4R40 A;  4FQ4 A;  4MZA A;  3H71 A;  4HZY A;  2HTQ A;  5B2D A;  4FPJ A;  1X2R A;  3K38 A;  1IJQ A;  1K32 A;  1OFZ A;  4HZW A;  4FPO B;  3SOB B;  4GZW A;  1L7F A;  4QN6 A;  4UF7 A;  4GNC A;  1NCA N;  1W21 A;  2F12 A;  4AHA A;  5D9C A;  3KGG A;  1INF A;  2VK6 A;  3JU4 A;  4CPO A;  1MS5 A;  2IAQ A;  3WW9 A;  2VW1 A;  3FVZ A;  1IVE A;  4XOG A;  4NCS A;  4D52 C;  3VNG A;  4HW6 A;  1RWI A;  2F0Z A;  3G4H A;  5EO8 A;  4FPH A;  2B8H A;  1V0F A;  3SIL A;  4YW5 A;  1V0Z A;  3GVJ A;  1W8N A;  1SLL A;  1ZI0 A;  3TIA A;  3GVK A;  1WCQ A;  2F26 A;  2QWK A;  4IFL X;  2F13 A;  1C9U A;  4D4U A;  4HHO A;  4Q1U A;  2C4A A;  1Z4X A;  3SOV A;  4N1B A;  1E8V A;  2F25 A;  2XZK A;  1XOG A;  1QBI A;  4GN8 A;  4M4U A;  4FVK A;  4CPM A;  4FOW A;  4YZ2 A;  4YZ3 A;  1NPE A;  3CKZ A;  1N1Y A;  3V65 B;  4B7M A;  3ALW A;  2IAX A;  3ZGC A;  4XHB A;  3NSS A;  2HQS A;  1V3E A;  3ADE A;  1S1D A;  4O5T A;  2ZZK A;  3CYE A;  1MWE A;  1NN2 A;  1INW A;  5HX0 A;  4IQK A;  3V64 C;  4XJA A;  4GNB A;  3HLI A;  2FP8 A;  1W0O A;  2DG0 A;  4XMA A;  4H53 A;  2XZJ A;  1NMB N;  3BYC A;  4YW2 A;  4FPF A;  4G3N A;  1IUB A;  1Z4Y A;  3KYA A;  3PJQ A;  2WOZ A;  1SNT A;  3T1E A;  3TIB A;  2HU4 A;  4MX0 A;  2AEQ A;  2ZB6 A;  3TI4 A;  1L7G A;  1E8T A;  3K36 A;  5FNT A;  3FW0 A; 
#chains in the Genus database with same CATH homology
 4C1Y B;  4D52 B;  1IUC A;  4UOU A;  1IUB A;  4D52 C;  4C1Y A;  5EO8 A;  5EO7 A;  4AGI A;  4AH4 A;  4CSD A;  4D52 A;  4D4U A;  1OFZ A;  5H47 A;  4AGT A;  4AHA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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