4G3N | Genus

Total Genus 85

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	85
sequence length	309
structure length	302
Chain Sequence	AREDVVVTITETGYAKRTKTDLYRSQKGAGLKQDDIVAHFFVCSTHDLILFFTTQGRVYRAKAYDLPEASRTARGQHVANLLAFQPEERIAQVIQIRGYTDAPYLVLATRNGLVKKSKLTDFDSNRSGGIVAVNLRDNDELVGAVLCSAGDDLLLVSANGQSIRFSATDEALRPMGRATSGVQGMRFNIDDRLLSLNVVREGTYLLVATSGGYAKRTAIEEYPVQGRGGKGVLTVMYDRRRGRLVGALIVDDDSELYAVTSGGGVIRTAARQVRKAGRQTKGVRLMNLGEGDTLLAIARNAE

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Isomerase
source organism	Mycobacterium tuberculosis
publication title	Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes. pubmed doi rcsb
molecule keywords	DNA gyrase subunit A
total genus	85
structure length	302
sequence length	309
ec nomenclature	ec 5.99.1.3: Transferred entry: 5.6.2.3.
pdb deposition date	2012-07-15

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF03989	DNA_gyraseA_C	DNA gyrase C-terminal domain, beta-propeller

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.120.10.90	Mainly Beta	6 Propeller	Neuraminidase	DNA gyrase/topoisomerase IV, subunit A, C-terminal	4g3nA00

3UC1A 3NO0A 1WP5A 1ZI0A 1SUUA 3L6VA 4G3NA
chains in the Genus database with same CATH superfamily

4WEGA 4YY8A 1MS4A 1S1DA 4IFJA 2BATA 3CKZA 3L6VA 1V3BA 1CRUA 3Q6TA 5F9TA 5B2DA 3GVKA 4MZAA 1E1AA 2RKCA 3HRPA 4XMAA 4KS3A 4ZGCA 2POOA 1IUCA 3H6JA 4XJZA 1V3DA 2VW0A 2QWHA 2QWBA 3SOQA 2HU4A 4C1YB 4K1HA 4YW5A 3TICA 2CMLA 2HQSA 2DG0A 4FZHA 2OJHA 4XIKA 4FOVA 2HTYA 2IAQA 3V64C 1NCCN 1INFA 2SILA 2ZB5A 4FPHA 2IAOA 5GX5A 3PJQA 4GDIA 4D8SA 4X4AA 1E8TA 4GZXA 4YW1A 2SLIA 4WA5A 4FPFA 1IVEA 1VCUA 4N1BA 2F12A 3P5BL 2AH2A 1N1YA 3H71A 4XHXA 2BERA 2VAQA 4IYGA 2W5OA 2DG1A 1WCQA 1VCJA 2SIMA 4FQ4A 4KS1A 2H2NA 5EX7A 1USRA 2XZIA 3BEQA 4MWXA 3ALXA 3TIBA 4YZ3A 1A4QA 2QWGA 4IFLX 5FNRA 1S18A 4GNCA 2VW1A 2HTQA 1H6LA 2YA6A 4CPMA 2XZJA 1EURA 1X2JA 3VNGA 4B7JA 3FVZA 1N7DA 4IMBA 4HW6A 3O4PA 3NO0A 1W8NA 1CVMA 2VSKA 4CSDA 2HTUA 1MS5A 1W21A 1IUBA 2GVWA 3D11A 5FNUA 3A9GA 3SANA 2VVZA 1IJQA 1ZGKA 1NSDA 1B9VA 2JKBA 1NNAA 4XJWA 2FPBA 3TI5A 1QLGA 1C9UA 4MWWA 1N1VA 4MWJA 5GX2A 2YA4A 3K38A 2QWAA 3I1CA 2B8HA 5D9CA 5FZNA 3U0SA 4BBWA 5M1ZA 1N1TA 3KYAA 4MWUA 2AEQA 1Z4YA 5HUMA 3V1SA 3CYEA 2VK7A 1L7FA 3JU4A 1CQ1A 4J9TA 1XOGA 1Z4XA 1PJXA 1V04A 2G8SA 4M3MA 4Q6KA 2AGSA 3UC1A 4HZYA 4D4UA 1F8CA 2DSOA 2QWEA 4XMIA 1EUTA 4GB1A 1NMAN 3SREA 2X9MA 3O9KA 1SO7A 4YZ2A 4HHQA 5JYYA 1F8DA 1IVCA 2QWJA 2VWDA 3ZGCA 1POOA 2C4AA 1NPEA 4IQKA 2VW2A 1IVDA 2IAXA 3TI3A 2BZDA 3TIAA 5FZJA 1MS8A 3S94A 2HTVA 3D12A 1NMBN 4NC5A 4HZVA 4MWQA 4G3NA 2IARA 2W8BA 3G4HA 3TI6A 5HUKA 3LI4A 4QN4A 1W8OA 3S8VA 1INHA 4MJUA 2GVUA 3A9HA 4B7RA 3Q6PA 4FPLA 1BJIA 3GVJA 1KITA 4GJTA 3HLIA 4QN3A 3SILA 3NN9A 2QWIA 2HU0A 4KS2A 2IVZA 3SRGA 2W8BB 1MZ5A 3GVLA 4FJ6A 1C5KA 2FLUX 3HLHA 2HT5A 5FNSA 2XN4A 3K37A 1EUSA 4FOYA 2F26A 2C4LA 3IAXA 1DIMA 4XIOA 4CPNA 1F8EA 4A0PA 4B7QA 2H2UA 4WA3A 1Z4VA 4ZLRA 1Z4WA 4UOUA 3WW9A 2F0ZA 3TC9A 4H52A 4YW3A 4L7DA 2ISMA 5FNTA 3TI8A 4AH4A 4GN7A 3BYCA 1Z50A 1IVFA 4K1KA 3VNHA 3V65B 3Q6KA 1MR5A 1DILA 2FHRA 3K39A 4B7NA 1A4GA 4CH9A 1W0PA 4WA4A 1N1SA 1E8VA 1L7GA 2GVVA 5NN9A 4KS4A 4FPGA 2QWCA 2QE8A 2Z32A 1IVGA 1NSCA 2F10A 4WEFA 4D52C 1USXA 4XHBA 4FP2A 1ZI0A 4HZZA 5GX3A 5HUGA 3TI4A 5FWWA 2VK5A 4YZ4A 1W20A 5D9DA 4GZQA 4MWVA 1OFZA 4M4NA 2P4OA 4PWZA 1SUUA 4MJVA 4O5TA 1B9TA 5B2CA 3DR2A 3WN7A 4HZWA 3B7EA 4XJRA 3ALWA 3H73A 3INBA 5HX0A 2W20A 3NSSA 4K1JA 2IAPA 4XJAA 4GEZA 1CRZA 4M4UA 1SLIA 1V2IA 4HHOA 3SOVA 1N6DA 2HTWA 4QNPA 2A75A 1XOEA 4GZOA 4GZSA 4XJ9A 4MX0A 2HTRA 1SLLA 4SLIA 2FP9A 4AGTA 4XILA 4FPCA 4FOWA 2IATA 1NCDN 4MZEA 1EUUA 3O9JA 2HT8A 4HZXA 4FOQA 4QN5A 4XJQA 4YW2A 2QWKA 3S2KA 4CPYA 4XOGA 4M4VA 1Z4ZA 4FPEA 2F11A 3LI3A 1INWA 1V3CA 4L7CA 3T1EA 2QWFA 4FPJA 4ZY3A 4Q1UA 4FP3A 4IN4A 3KGGA 4AHAA 5GX4A 1NCBN 4ASCA 4XYXA 4H53A 3WDZA 3WWAA 1W0OA 5H47A 3B69A 2F24A 4FPKA 1RWLA 4IFNX 2VSMA 4DG6A 4QN6A 1NNBA 5CGJA 1N6EA 4GDJA 4CPLA 4YZ1A 2WOZA 2FPCA 2GHSA 1E8UA 2YDPA 1MZ6A 2F27A 1V0ZA 4HIZA 2XZKA 2QWDA 4B7MA 2ZB6A 1S0IA 1INVA 4XMBA 4MWLA 2GVXA 4D52A 1NNCA 4XJ8A 3ZGDA 4K1IA 3SOBB 4UF7A 4GN9A 1Q7FA 4GNBA 4JF7A 4GNAA 4X49A 3CL0A 3K3AA 2F28A 2IASA 1B9SA 4YZ5A 1INXA 2F29A 4QN7A 3OPZA 1INGA 3A71A 3AMSA 4FVKA 2W5NA 5HUNA 1N6FA 1QBIA 4FPOB 1L7HA 3SLIA 4D52B 4MC7A 2BF6A 3DASA 4GZPA 1SNTA 5D9BA 5EO8A 1NN2A 1WCSA 3II7A 5GTQA 4L7BA 1MS0A 4AGIA 1MWEA 3K36A 2YDTA 4XE9A 4FPYA 2HT7A 4K3YA 5F72C 1NCAN 3E5ZA 4GZWA 3CL2A 1IVBA 1S0JA 5GX1A 4CPOA 1RWIA 1NSBA 3S8ZA 2V91A 2VPJA 7NN9A 1MS3A 4O5SA 2IAVA 3AMRA 4CPZA 2YA7A 3H72A 1MS9A 2YA5A 1V0FA 3ADEA 1F8BA 2AEPA 4NCSA 5EO7A 4I00A 2IAUA 1V0EA 6NN9A 2IAWA 3W09A 2DYHA 2ZWAA 4CHBA 1MS1A 1NMCA 2F25A 2VK6A 3FW0A 5FNQA 4XJUA 1X2RA 2FP8A 3G4EA 3A72A 4YW4A 1K32A 1V3EA 4GN8A 4NN9A 3LI5A 3SALA 2ZW9A 2YA8A 4GZTA 4KS5A 4MWRA 1U6DX 2ZZKA 1W1XA 4JMLA 4C1YA 4MWYA 2XCYA 4DGRA 4R40A 1INYA 1WP5A 4X6KA 4X47A 2F13A 2W38A 1A14N
chains in the Genus database with same CATH topology

3UC1A 3NO0A 1WP5A 1ZI0A 1SUUA 3L6VA 4G3NA
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 3UC1 A;  3NO0 A;  1WP5 A;  1ZI0 A;  1SUU A;  3L6V A;  4G3N A; 
#chains in the Genus database with same CATH topology
 4WEG A;  4YY8 A;  1MS4 A;  1S1D A;  4IFJ A;  2BAT A;  3CKZ A;  3L6V A;  1V3B A;  1CRU A;  3Q6T A;  5F9T A;  5B2D A;  3GVK A;  4MZA A;  1E1A A;  2RKC A;  3HRP A;  4XMA A;  4KS3 A;  4ZGC A;  2POO A;  1IUC A;  3H6J A;  4XJZ A;  1V3D A;  2VW0 A;  2QWH A;  2QWB A;  3SOQ A;  2HU4 A;  4C1Y B;  4K1H A;  4YW5 A;  3TIC A;  2CML A;  2HQS A;  2DG0 A;  4FZH A;  2OJH A;  4XIK A;  4FOV A;  2HTY A;  2IAQ A;  3V64 C;  1NCC N;  1INF A;  2SIL A;  2ZB5 A;  4FPH A;  2IAO A;  5GX5 A;  3PJQ A;  4GDI A;  4D8S A;  4X4A A;  1E8T A;  4GZX A;  4YW1 A;  2SLI A;  4WA5 A;  4FPF A;  1IVE A;  1VCU A;  4N1B A;  2F12 A;  3P5B L;  2AH2 A;  1N1Y A;  3H71 A;  4XHX A;  2BER A;  2VAQ A;  4IYG A;  2W5O A;  2DG1 A;  1WCQ A;  1VCJ A;  2SIM A;  4FQ4 A;  4KS1 A;  2H2N A;  5EX7 A;  1USR A;  2XZI A;  3BEQ A;  4MWX A;  3ALX A;  3TIB A;  4YZ3 A;  1A4Q A;  2QWG A;  4IFL X;  5FNR A;  1S18 A;  4GNC A;  2VW1 A;  2HTQ A;  1H6L A;  2YA6 A;  4CPM A;  2XZJ A;  1EUR A;  1X2J A;  3VNG A;  4B7J A;  3FVZ A;  1N7D A;  4IMB A;  4HW6 A;  3O4P A;  3NO0 A;  1W8N A;  1CVM A;  2VSK A;  4CSD A;  2HTU A;  1MS5 A;  1W21 A;  1IUB A;  2GVW A;  3D11 A;  5FNU A;  3A9G A;  3SAN A;  2VVZ A;  1IJQ A;  1ZGK A;  1NSD A;  1B9V A;  2JKB A;  1NNA A;  4XJW A;  2FPB A;  3TI5 A;  1QLG A;  1C9U A;  4MWW A;  1N1V A;  4MWJ A;  5GX2 A;  2YA4 A;  3K38 A;  2QWA A;  3I1C A;  2B8H A;  5D9C A;  5FZN A;  3U0S A;  4BBW A;  5M1Z A;  1N1T A;  3KYA A;  4MWU A;  2AEQ A;  1Z4Y A;  5HUM A;  3V1S A;  3CYE A;  2VK7 A;  1L7F A;  3JU4 A;  1CQ1 A;  4J9T A;  1XOG A;  1Z4X A;  1PJX A;  1V04 A;  2G8S A;  4M3M A;  4Q6K A;  2AGS A;  3UC1 A;  4HZY A;  4D4U A;  1F8C A;  2DSO A;  2QWE A;  4XMI A;  1EUT A;  4GB1 A;  1NMA N;  3SRE A;  2X9M A;  3O9K A;  1SO7 A;  4YZ2 A;  4HHQ A;  5JYY A;  1F8D A;  1IVC A;  2QWJ A;  2VWD A;  3ZGC A;  1POO A;  2C4A A;  1NPE A;  4IQK A;  2VW2 A;  1IVD A;  2IAX A;  3TI3 A;  2BZD A;  3TIA A;  5FZJ A;  1MS8 A;  3S94 A;  2HTV A;  3D12 A;  1NMB N;  4NC5 A;  4HZV A;  4MWQ A;  4G3N A;  2IAR A;  2W8B A;  3G4H A;  3TI6 A;  5HUK A;  3LI4 A;  4QN4 A;  1W8O A;  3S8V A;  1INH A;  4MJU A;  2GVU A;  3A9H A;  4B7R A;  3Q6P A;  4FPL A;  1BJI A;  3GVJ A;  1KIT A;  4GJT A;  3HLI A;  4QN3 A;  3SIL A;  3NN9 A;  2QWI A;  2HU0 A;  4KS2 A;  2IVZ A;  3SRG A;  2W8B B;  1MZ5 A;  3GVL A;  4FJ6 A;  1C5K A;  2FLU X;  3HLH A;  2HT5 A;  5FNS A;  2XN4 A;  3K37 A;  1EUS A;  4FOY A;  2F26 A;  2C4L A;  3IAX A;  1DIM A;  4XIO A;  4CPN A;  1F8E A;  4A0P A;  4B7Q A;  2H2U A;  4WA3 A;  1Z4V A;  4ZLR A;  1Z4W A;  4UOU A;  3WW9 A;  2F0Z A;  3TC9 A;  4H52 A;  4YW3 A;  4L7D A;  2ISM A;  5FNT A;  3TI8 A;  4AH4 A;  4GN7 A;  3BYC A;  1Z50 A;  1IVF A;  4K1K A;  3VNH A;  3V65 B;  3Q6K A;  1MR5 A;  1DIL A;  2FHR A;  3K39 A;  4B7N A;  1A4G A;  4CH9 A;  1W0P A;  4WA4 A;  1N1S A;  1E8V A;  1L7G A;  2GVV A;  5NN9 A;  4KS4 A;  4FPG A;  2QWC A;  2QE8 A;  2Z32 A;  1IVG A;  1NSC A;  2F10 A;  4WEF A;  4D52 C;  1USX A;  4XHB A;  4FP2 A;  1ZI0 A;  4HZZ A;  5GX3 A;  5HUG A;  3TI4 A;  5FWW A;  2VK5 A;  4YZ4 A;  1W20 A;  5D9D A;  4GZQ A;  4MWV A;  1OFZ A;  4M4N A;  2P4O A;  4PWZ A;  1SUU A;  4MJV A;  4O5T A;  1B9T A;  5B2C A;  3DR2 A;  3WN7 A;  4HZW A;  3B7E A;  4XJR A;  3ALW A;  3H73 A;  3INB A;  5HX0 A;  2W20 A;  3NSS A;  4K1J A;  2IAP A;  4XJA A;  4GEZ A;  1CRZ A;  4M4U A;  1SLI A;  1V2I A;  4HHO A;  3SOV A;  1N6D A;  2HTW A;  4QNP A;  2A75 A;  1XOE A;  4GZO A;  4GZS A;  4XJ9 A;  4MX0 A;  2HTR A;  1SLL A;  4SLI A;  2FP9 A;  4AGT A;  4XIL A;  4FPC A;  4FOW A;  2IAT A;  1NCD N;  4MZE A;  1EUU A;  3O9J A;  2HT8 A;  4HZX A;  4FOQ A;  4QN5 A;  4XJQ A;  4YW2 A;  2QWK A;  3S2K A;  4CPY A;  4XOG A;  4M4V A;  1Z4Z A;  4FPE A;  2F11 A;  3LI3 A;  1INW A;  1V3C A;  4L7C A;  3T1E A;  2QWF A;  4FPJ A;  4ZY3 A;  4Q1U A;  4FP3 A;  4IN4 A;  3KGG A;  4AHA A;  5GX4 A;  1NCB N;  4ASC A;  4XYX A;  4H53 A;  3WDZ A;  3WWA A;  1W0O A;  5H47 A;  3B69 A;  2F24 A;  4FPK A;  1RWL A;  4IFN X;  2VSM A;  4DG6 A;  4QN6 A;  1NNB A;  5CGJ A;  1N6E A;  4GDJ A;  4CPL A;  4YZ1 A;  2WOZ A;  2FPC A;  2GHS A;  1E8U A;  2YDP A;  1MZ6 A;  2F27 A;  1V0Z A;  4HIZ A;  2XZK A;  2QWD A;  4B7M A;  2ZB6 A;  1S0I A;  1INV A;  4XMB A;  4MWL A;  2GVX A;  4D52 A;  1NNC A;  4XJ8 A;  3ZGD A;  4K1I A;  3SOB B;  4UF7 A;  4GN9 A;  1Q7F A;  4GNB A;  4JF7 A;  4GNA A;  4X49 A;  3CL0 A;  3K3A A;  2F28 A;  2IAS A;  1B9S A;  4YZ5 A;  1INX A;  2F29 A;  4QN7 A;  3OPZ A;  1ING A;  3A71 A;  3AMS A;  4FVK A;  2W5N A;  5HUN A;  1N6F A;  1QBI A;  4FPO B;  1L7H A;  3SLI A;  4D52 B;  4MC7 A;  2BF6 A;  3DAS A;  4GZP A;  1SNT A;  5D9B A;  5EO8 A;  1NN2 A;  1WCS A;  3II7 A;  5GTQ A;  4L7B A;  1MS0 A;  4AGI A;  1MWE A;  3K36 A;  2YDT A;  4XE9 A;  4FPY A;  2HT7 A;  4K3Y A;  5F72 C;  1NCA N;  3E5Z A;  4GZW A;  3CL2 A;  1IVB A;  1S0J A;  5GX1 A;  4CPO A;  1RWI A;  1NSB A;  3S8Z A;  2V91 A;  2VPJ A;  7NN9 A;  1MS3 A;  4O5S A;  2IAV A;  3AMR A;  4CPZ A;  2YA7 A;  3H72 A;  1MS9 A;  2YA5 A;  1V0F A;  3ADE A;  1F8B A;  2AEP A;  4NCS A;  5EO7 A;  4I00 A;  2IAU A;  1V0E A;  6NN9 A;  2IAW A;  3W09 A;  2DYH A;  2ZWA A;  4CHB A;  1MS1 A;  1NMC A;  2F25 A;  2VK6 A;  3FW0 A;  5FNQ A;  4XJU A;  1X2R A;  2FP8 A;  3G4E A;  3A72 A;  4YW4 A;  1K32 A;  1V3E A;  4GN8 A;  4NN9 A;  3LI5 A;  3SAL A;  2ZW9 A;  2YA8 A;  4GZT A;  4KS5 A;  4MWR A;  1U6D X;  2ZZK A;  1W1X A;  4JML A;  4C1Y A;  4MWY A;  2XCY A;  4DGR A;  4R40 A;  1INY A;  1WP5 A;  4X6K A;  4X47 A;  2F13 A;  2W38 A;  1A14 N; 
#chains in the Genus database with same CATH homology
 3UC1 A;  3NO0 A;  1WP5 A;  1ZI0 A;  1SUU A;  3L6V A;  4G3N A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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4G3NA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations