4IFJA

Crystal structures of apo keap1, keap1-peptide, and keap1-compound complexes
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
288
structure length
288
Chain Sequence
PKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes
rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Kelch-like ECH-associated protein 1
total genus 68
structure length 288
sequence length 288
ec nomenclature
pdb deposition date 2012-12-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 4ifjA00
1X2RA 3ZGCA 1ZGKA 5FNTA 5F72C 2ZW9A 4N1BA 5CGJA 1U6DX 4IFLX 2Z32A 4L7BA 4ZY3A 4IN4A 2DYHA 4L7CA 5FNQA 5FNRA 3VNGA 3ZGDA 4ASCA 2ZWAA 2VPJA 3WN7A 2ZZKA 3II7A 5FZNA 5FNUA 3WDZA 4IQKA 4CH9A 4IFNX 5FZJA 4IFJA 2FLUX 4XMBA 2WOZA 3VNHA 3ADEA 4YY8A 4L7DA 2XN4A 5FNSA 1X2JA 4ZGCA 4CHBA
chains in the Genus database with same CATH superfamily
2W38A 4NCSA 4XJ9A 1NSBA 1Z4YA 2W8BB 4XJWA 3S8VA 1U6DX 3FVZA 4YZ1A 4XJ8A 4GNBA 1EURA 1N1VA 1INWA 2FPBA 2VK6A 2XCYA 3O9JA 1H6LA 3ALWA 5HUMA 4AGTA 4B7RA 3INBA 1V3EA 2C4AA 1E8VA 2QE8A 4HIZA 1MR5A 1SO7A 2HTRA 4FPJA 2QWDA 1Z50A 2VK5A 1USXA 1XOEA 2DG0A 5JYYA 5F72C 5GTQA 6NN9A 4XMIA 2HQSA 3OPZA 1INVA 3GVKA 4D52C 2AEQA 4IN4A 1E8UA 4L7CA 4ASCA 4D4UA 2BATA 4QNPA 4FPYA 1WP5A 5H47A 4CPYA 2IASA 2F25A 4FOQA 4KS1A 3G4HA 2VVZA 4XHBA 5GX5A 1N1SA 4XIOA 3FW0A 2G8SA 4XJRA 1W0PA 4FPFA 3AMSA 2QWGA 2C4LA 4HHOA 5GX2A 4C1YB 2IATA 3TC9A 4GZQA 1NMBN 2IAPA 4KS3A 4NN9A 1Z4XA 2SIMA 1IVDA 4GDJA 2ZZKA 3CYEA 4YZ3A 1NMCA 2YA5A 2YA8A 4MWJA 3DR2A 4QN5A 4CHBA 4YW2A 2YDPA 3SILA 2IAXA 1V0FA 3SOQA 3UC1A 3CL2A 4HW6A 1MS9A 4FPCA 3SREA 2VSMA 1MZ6A 4GZOA 3GVJA 1V3BA 2F24A 3G4EA 5HUGA 5NN9A 1DILA 4YW5A 4MWVA 4UF7A 3A72A 2YA6A 2A75A 4XMBA 1ZI0A 2F29A 1W21A 3TICA 3NO0A 4B7JA 4A0PA 1S0IA 1MS1A 4X49A 2F26A 4WA5A 2DSOA 3K3AA 4KS5A 1L7HA 3DASA 1V2IA 3I1CA 2IAUA 2W8BA 3CL0A 5EO7A 1SLLA 4MC7A 1S0JA 2HTWA 3AMRA 4B7QA 1QBIA 1SLIA 1W1XA 3TIAA 3U0SA 3SRGA 3TI3A 1V0ZA 5GX1A 4H53A 2AGSA 2XZKA 4IFNX 2VW0A 4CPNA 3S8ZA 3H6JA 5M1ZA 2FP9A 5HX0A 1NN2A 4O5TA 4K1IA 1VCJA 5FNTA 1EUTA 4GNAA 4GB1A 3E5ZA 2Z32A 2IAVA 3VNGA 1S1DA 2ZWAA 1L7FA 4GZXA 4DG6A 2AH2A 4D52B 1K32A 2QWEA 4FVKA 4IQKA 1IUCA 1C5KA 5HUNA 4GZSA 4CPLA 2H2NA 1WCQA 4YZ2A 4I00A 2JKBA 4GDIA 1PJXA 2F28A 2YA4A 3V64C 4JF7A 2QWJA 2QWIA 2P4OA 5CGJA 4GZWA 4FPOB 4C1YA 2HT8A 4ZY3A 4FOWA 1IVCA 4FP3A 2BF6A 4X4AA 3H73A 2GVVA 1MS0A 1F8BA 2F10A 4MWUA 4NC5A 1MS4A 3SLIA 5B2DA 4FPKA 3A9GA 1W20A 4YY8A 2ISMA 2RKCA 1NNCA 5D9CA 1INFA 2IVZA 1ZGKA 1IVEA 1KITA 4N1BA 2HTVA 2DG1A 1EUSA 4IMBA 3H71A 3IAXA 4AHAA 3TI5A 4H52A 3Q6KA 4UOUA 1W8OA 2FHRA 2QWAA 3O4PA 1VCUA 4JMLA 1RWLA 4AH4A 4MWXA 2BERA 2F13A 1F8DA 5D9BA 3SOVA 4DGRA 4HZVA 3A71A 4J9TA 4ZGCA 3S94A 1NCBN 1IVGA 2HTUA 1INXA 4HHQA 2W20A 4MWQA 4XHXA 4L7BA 1B9SA 3K37A 4XOGA 4QN4A 2GVWA 3K36A 3ZGDA 1POOA 4GN8A 3SALA 1W0OA 4MJVA 3LI3A 4YW3A 5GX3A 1MS8A 3HRPA 2FPCA 4CPOA 4CPZA 3BEQA 3BYCA 4M3MA 3S2KA 2IAWA 4M4NA 2XZJA 3T1EA 4IYGA 4BBWA 3WWAA 4XJZA 1IUBA 3D11A 4M4VA 4X6KA 4K3YA 4GN7A 5FZNA 3O9KA 2X9MA 2YDTA 1WCSA 4D52A 2HT7A 2CMLA 3ADEA 1RWIA 4K1KA 1CRUA 2B8HA 3TI6A 3LI4A 2HU0A 1DIMA 3LI5A 5EX7A 4XMAA 1F8CA 1MS5A 2VK7A 1IVBA 4HZWA 1B9TA 2QWHA 1MWEA 1N1TA 4HZXA 1E8TA 3SOBB 1N7DA 1INYA 3KYAA 3TI8A 1W8NA 1A4GA 1Z4ZA 4G3NA 1Z4VA 1SNTA 3K38A 4YW1A 4M4UA 2IAQA 3SANA 2ZB5A 3V1SA 2SLIA 2QWFA 1CVMA 3HLHA 1E1AA 2VW1A 3A9HA 1N6DA 4XJUA 4HZYA 3H72A 4GZTA 3B7EA 2VPJA 2W5OA 5HUKA 4O5SA 2HU4A 1V3DA 4AGIA 4MWLA 4GJTA 4FPLA 3ALXA 4ZLRA 1NNAA 2HT5A 3W09A 4HZZA 4FP2A 2WOZA 5B2CA 4L7DA 2XN4A 1X2RA 2VWDA 4FPGA 4WA4A 4GNCA 3Q6TA 2GHSA 4GEZA 4MZAA 4B7MA 4FPHA 1CQ1A 4GZPA 4MX0A 4IFLX 2BZDA 4MWRA 1IJQA 1V04A 2QWBA 3P5BL 1INGA 1C9UA 2HTQA 4Q6KA 1B9VA 1N6FA 4FPEA 3GVLA 1L7GA 5FWWA 3KGGA 4SLIA 3NSSA 1V0EA 5FZJA 2GVUA 4MZEA 5GX4A 1A14N 1NCAN 1NCCN 2F11A 2HTYA 4FZHA 4KS4A 2QWCA 3PJQA 4MWYA 4CSDA 1V3CA 4PWZA 4Q1UA 2F12A 1NNBA 1N6EA 3JU4A 4YZ5A 5FNQA 4FJ6A 3NN9A 2V91A 3WN7A 1NMAN 1SUUA 2F0ZA 4MJUA 3D12A 4QN7A 4FQ4A 4WEGA 5FNUA 4FOYA 1USRA 4XJQA 2FLUX 4QN6A 4XJAA 3K39A 2ZB6A 4WA3A 3ZGCA 1NCDN 1MS3A 5EO8A 2VAQA 4R40A 4X47A 4XYXA 1F8EA 3L6VA 1Z4WA 2IAOA 1XOGA 4MWWA 3B69A 1NSDA 5FNRA 3V65B 1S18A 2OJHA 3II7A 5D9DA 1IVFA 1NSCA 1EUUA 4XILA 1OFZA 3WDZA 4KS2A 4K1JA 1N1YA 3VNHA 2W5NA 2YA7A 5FNSA 1X2JA 4YZ4A 3HLIA 4WEFA 2ZW9A 1BJIA 1INHA 4XE9A 1A4QA 2GVXA 2VSKA 2F27A 2VW2A 7NN9A 2DYHA 3CKZA 4YW4A 4D8SA 3Q6PA 5F9TA 1Q7FA 2SILA 3WW9A 1MZ5A 4K1HA 2QWKA 1CRZA 1QLGA 2FP8A 4B7NA 4XIKA 2H2UA 2IARA 3TIBA 2XZIA 4CH9A 3TI4A 4IFJA 1NPEA 2POOA 4FOVA 2AEPA 4CPMA 4GN9A 4QN3A
chains in the Genus database with same CATH topology
1X2RA 3ZGCA 1ZGKA 5FNTA 5F72C 2ZW9A 4N1BA 5CGJA 1U6DX 4IFLX 2Z32A 4L7BA 4ZY3A 4IN4A 2DYHA 4L7CA 5FNQA 5FNRA 3VNGA 3ZGDA 4ASCA 2ZWAA 2VPJA 3WN7A 2ZZKA 3II7A 5FZNA 5FNUA 3WDZA 4IQKA 4CH9A 4IFNX 5FZJA 4IFJA 2FLUX 4XMBA 2WOZA 3VNHA 3ADEA 4YY8A 4L7DA 2XN4A 5FNSA 1X2JA 4ZGCA 4CHBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X2R A;  3ZGC A;  1ZGK A;  5FNT A;  5F72 C;  2ZW9 A;  4N1B A;  5CGJ A;  1U6D X;  4IFL X;  2Z32 A;  4L7B A;  4ZY3 A;  4IN4 A;  2DYH A;  4L7C A;  5FNQ A;  5FNR A;  3VNG A;  3ZGD A;  4ASC A;  2ZWA A;  2VPJ A;  3WN7 A;  2ZZK A;  3II7 A;  5FZN A;  5FNU A;  3WDZ A;  4IQK A;  4CH9 A;  4IFN X;  5FZJ A;  4IFJ A;  2FLU X;  4XMB A;  2WOZ A;  3VNH A;  3ADE A;  4YY8 A;  4L7D A;  2XN4 A;  5FNS A;  1X2J A;  4ZGC A;  4CHB A; 
#chains in the Genus database with same CATH topology
 2W38 A;  4NCS A;  4XJ9 A;  1NSB A;  1Z4Y A;  2W8B B;  4XJW A;  3S8V A;  1U6D X;  3FVZ A;  4YZ1 A;  4XJ8 A;  4GNB A;  1EUR A;  1N1V A;  1INW A;  2FPB A;  2VK6 A;  2XCY A;  3O9J A;  1H6L A;  3ALW A;  5HUM A;  4AGT A;  4B7R A;  3INB A;  1V3E A;  2C4A A;  1E8V A;  2QE8 A;  4HIZ A;  1MR5 A;  1SO7 A;  2HTR A;  4FPJ A;  2QWD A;  1Z50 A;  2VK5 A;  1USX A;  1XOE A;  2DG0 A;  5JYY A;  5F72 C;  5GTQ A;  6NN9 A;  4XMI A;  2HQS A;  3OPZ A;  1INV A;  3GVK A;  4D52 C;  2AEQ A;  4IN4 A;  1E8U A;  4L7C A;  4ASC A;  4D4U A;  2BAT A;  4QNP A;  4FPY A;  1WP5 A;  5H47 A;  4CPY A;  2IAS A;  2F25 A;  4FOQ A;  4KS1 A;  3G4H A;  2VVZ A;  4XHB A;  5GX5 A;  1N1S A;  4XIO A;  3FW0 A;  2G8S A;  4XJR A;  1W0P A;  4FPF A;  3AMS A;  2QWG A;  2C4L A;  4HHO A;  5GX2 A;  4C1Y B;  2IAT A;  3TC9 A;  4GZQ A;  1NMB N;  2IAP A;  4KS3 A;  4NN9 A;  1Z4X A;  2SIM A;  1IVD A;  4GDJ A;  2ZZK A;  3CYE A;  4YZ3 A;  1NMC A;  2YA5 A;  2YA8 A;  4MWJ A;  3DR2 A;  4QN5 A;  4CHB A;  4YW2 A;  2YDP A;  3SIL A;  2IAX A;  1V0F A;  3SOQ A;  3UC1 A;  3CL2 A;  4HW6 A;  1MS9 A;  4FPC A;  3SRE A;  2VSM A;  1MZ6 A;  4GZO A;  3GVJ A;  1V3B A;  2F24 A;  3G4E A;  5HUG A;  5NN9 A;  1DIL A;  4YW5 A;  4MWV A;  4UF7 A;  3A72 A;  2YA6 A;  2A75 A;  4XMB A;  1ZI0 A;  2F29 A;  1W21 A;  3TIC A;  3NO0 A;  4B7J A;  4A0P A;  1S0I A;  1MS1 A;  4X49 A;  2F26 A;  4WA5 A;  2DSO A;  3K3A A;  4KS5 A;  1L7H A;  3DAS A;  1V2I A;  3I1C A;  2IAU A;  2W8B A;  3CL0 A;  5EO7 A;  1SLL A;  4MC7 A;  1S0J A;  2HTW A;  3AMR A;  4B7Q A;  1QBI A;  1SLI A;  1W1X A;  3TIA A;  3U0S A;  3SRG A;  3TI3 A;  1V0Z A;  5GX1 A;  4H53 A;  2AGS A;  2XZK A;  4IFN X;  2VW0 A;  4CPN A;  3S8Z A;  3H6J A;  5M1Z A;  2FP9 A;  5HX0 A;  1NN2 A;  4O5T A;  4K1I A;  1VCJ A;  5FNT A;  1EUT A;  4GNA A;  4GB1 A;  3E5Z A;  2Z32 A;  2IAV A;  3VNG A;  1S1D A;  2ZWA A;  1L7F A;  4GZX A;  4DG6 A;  2AH2 A;  4D52 B;  1K32 A;  2QWE A;  4FVK A;  4IQK A;  1IUC A;  1C5K A;  5HUN A;  4GZS A;  4CPL A;  2H2N A;  1WCQ A;  4YZ2 A;  4I00 A;  2JKB A;  4GDI A;  1PJX A;  2F28 A;  2YA4 A;  3V64 C;  4JF7 A;  2QWJ A;  2QWI A;  2P4O A;  5CGJ A;  4GZW A;  4FPO B;  4C1Y A;  2HT8 A;  4ZY3 A;  4FOW A;  1IVC A;  4FP3 A;  2BF6 A;  4X4A A;  3H73 A;  2GVV A;  1MS0 A;  1F8B A;  2F10 A;  4MWU A;  4NC5 A;  1MS4 A;  3SLI A;  5B2D A;  4FPK A;  3A9G A;  1W20 A;  4YY8 A;  2ISM A;  2RKC A;  1NNC A;  5D9C A;  1INF A;  2IVZ A;  1ZGK A;  1IVE A;  1KIT A;  4N1B A;  2HTV A;  2DG1 A;  1EUS A;  4IMB A;  3H71 A;  3IAX A;  4AHA A;  3TI5 A;  4H52 A;  3Q6K A;  4UOU A;  1W8O A;  2FHR A;  2QWA A;  3O4P A;  1VCU A;  4JML A;  1RWL A;  4AH4 A;  4MWX A;  2BER A;  2F13 A;  1F8D A;  5D9B A;  3SOV A;  4DGR A;  4HZV A;  3A71 A;  4J9T A;  4ZGC A;  3S94 A;  1NCB N;  1IVG A;  2HTU A;  1INX A;  4HHQ A;  2W20 A;  4MWQ A;  4XHX A;  4L7B A;  1B9S A;  3K37 A;  4XOG A;  4QN4 A;  2GVW A;  3K36 A;  3ZGD A;  1POO A;  4GN8 A;  3SAL A;  1W0O A;  4MJV A;  3LI3 A;  4YW3 A;  5GX3 A;  1MS8 A;  3HRP A;  2FPC A;  4CPO A;  4CPZ A;  3BEQ A;  3BYC A;  4M3M A;  3S2K A;  2IAW A;  4M4N A;  2XZJ A;  3T1E A;  4IYG A;  4BBW A;  3WWA A;  4XJZ A;  1IUB A;  3D11 A;  4M4V A;  4X6K A;  4K3Y A;  4GN7 A;  5FZN A;  3O9K A;  2X9M A;  2YDT A;  1WCS A;  4D52 A;  2HT7 A;  2CML A;  3ADE A;  1RWI A;  4K1K A;  1CRU A;  2B8H A;  3TI6 A;  3LI4 A;  2HU0 A;  1DIM A;  3LI5 A;  5EX7 A;  4XMA A;  1F8C A;  1MS5 A;  2VK7 A;  1IVB A;  4HZW A;  1B9T A;  2QWH A;  1MWE A;  1N1T A;  4HZX A;  1E8T A;  3SOB B;  1N7D A;  1INY A;  3KYA A;  3TI8 A;  1W8N A;  1A4G A;  1Z4Z A;  4G3N A;  1Z4V A;  1SNT A;  3K38 A;  4YW1 A;  4M4U A;  2IAQ A;  3SAN A;  2ZB5 A;  3V1S A;  2SLI A;  2QWF A;  1CVM A;  3HLH A;  1E1A A;  2VW1 A;  3A9H A;  1N6D A;  4XJU A;  4HZY A;  3H72 A;  4GZT A;  3B7E A;  2VPJ A;  2W5O A;  5HUK A;  4O5S A;  2HU4 A;  1V3D A;  4AGI A;  4MWL A;  4GJT A;  4FPL A;  3ALX A;  4ZLR A;  1NNA A;  2HT5 A;  3W09 A;  4HZZ A;  4FP2 A;  2WOZ A;  5B2C A;  4L7D A;  2XN4 A;  1X2R A;  2VWD A;  4FPG A;  4WA4 A;  4GNC A;  3Q6T A;  2GHS A;  4GEZ A;  4MZA A;  4B7M A;  4FPH A;  1CQ1 A;  4GZP A;  4MX0 A;  4IFL X;  2BZD A;  4MWR A;  1IJQ A;  1V04 A;  2QWB A;  3P5B L;  1ING A;  1C9U A;  2HTQ A;  4Q6K A;  1B9V A;  1N6F A;  4FPE A;  3GVL A;  1L7G A;  5FWW A;  3KGG A;  4SLI A;  3NSS A;  1V0E A;  5FZJ A;  2GVU A;  4MZE A;  5GX4 A;  1A14 N;  1NCA N;  1NCC N;  2F11 A;  2HTY A;  4FZH A;  4KS4 A;  2QWC A;  3PJQ A;  4MWY A;  4CSD A;  1V3C A;  4PWZ A;  4Q1U A;  2F12 A;  1NNB A;  1N6E A;  3JU4 A;  4YZ5 A;  5FNQ A;  4FJ6 A;  3NN9 A;  2V91 A;  3WN7 A;  1NMA N;  1SUU A;  2F0Z A;  4MJU A;  3D12 A;  4QN7 A;  4FQ4 A;  4WEG A;  5FNU A;  4FOY A;  1USR A;  4XJQ A;  2FLU X;  4QN6 A;  4XJA A;  3K39 A;  2ZB6 A;  4WA3 A;  3ZGC A;  1NCD N;  1MS3 A;  5EO8 A;  2VAQ A;  4R40 A;  4X47 A;  4XYX A;  1F8E A;  3L6V A;  1Z4W A;  2IAO A;  1XOG A;  4MWW A;  3B69 A;  1NSD A;  5FNR A;  3V65 B;  1S18 A;  2OJH A;  3II7 A;  5D9D A;  1IVF A;  1NSC A;  1EUU A;  4XIL A;  1OFZ A;  3WDZ A;  4KS2 A;  4K1J A;  1N1Y A;  3VNH A;  2W5N A;  2YA7 A;  5FNS A;  1X2J A;  4YZ4 A;  3HLI A;  4WEF A;  2ZW9 A;  1BJI A;  1INH A;  4XE9 A;  1A4Q A;  2GVX A;  2VSK A;  2F27 A;  2VW2 A;  7NN9 A;  2DYH A;  3CKZ A;  4YW4 A;  4D8S A;  3Q6P A;  5F9T A;  1Q7F A;  2SIL A;  3WW9 A;  1MZ5 A;  4K1H A;  2QWK A;  1CRZ A;  1QLG A;  2FP8 A;  4B7N A;  4XIK A;  2H2U A;  2IAR A;  3TIB A;  2XZI A;  4CH9 A;  3TI4 A;  4IFJ A;  1NPE A;  2POO A;  4FOV A;  2AEP A;  4CPM A;  4GN9 A;  4QN3 A; 
#chains in the Genus database with same CATH homology
 1X2R A;  3ZGC A;  1ZGK A;  5FNT A;  5F72 C;  2ZW9 A;  4N1B A;  5CGJ A;  1U6D X;  4IFL X;  2Z32 A;  4L7B A;  4ZY3 A;  4IN4 A;  2DYH A;  4L7C A;  5FNQ A;  5FNR A;  3VNG A;  3ZGD A;  4ASC A;  2ZWA A;  2VPJ A;  3WN7 A;  2ZZK A;  3II7 A;  5FZN A;  5FNU A;  3WDZ A;  4IQK A;  4CH9 A;  4IFN X;  5FZJ A;  4IFJ A;  2FLU X;  4XMB A;  2WOZ A;  3VNH A;  3ADE A;  4YY8 A;  4L7D A;  2XN4 A;  5FNS A;  1X2J A;  4ZGC A;  4CHB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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