4AH4A

Crystal structure of fucose binding lectin from aspergillus fumigatus (afl) in complex with bga oligosaccharide.
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
314
structure length
313
Chain Sequence
STPGAQQVLFRTGIAAVNSTNHLRVYFQDVYGSIRESLYEGSWANGTEKNVIGNAKLGSPVAATSKELKHIRVYTLTEGNTLQEFAYDSGTGWYNGGLGGAKFQVAPYSCIAAVFLAGTDALQLRIYAQKPDNTIQEYMWNGDGWKEGTNLGGALPGTGIGATSFRYTDYNGPSIRIWFQTDDLKLVQRAYDPHKGWYPDLVTIFDRAPPRTAIAATSFGAGNSSIYMRIYFVNSDNTIWQVWDHGKGYHDKGTITPVIQGSEVAIISWGSFANNGPDLRLYFQNGTYISAVSEWVWNRAHGSQLGRSALPPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Insights Into Aspergillus Fumigatus Lectin Specificity: Afl Binding Sites are Functionally Non-Equivalent
pubmed doi rcsb
molecule tags Sugar binding protein
source organism Aspergillus fumigatus
molecule keywords FUCOSE-SPECIFIC LECTIN FLEA
total genus 82
structure length 313
sequence length 314
chains with identical sequence B
ec nomenclature
pdb deposition date 2012-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07938 Fungal_lectin Fungal fucose-specific lectin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.70 Mainly Beta 6 Propeller Neuraminidase Fucose-specific lectin 4ah4A00
4D52A 4D52C 4D52B 4AH4A 4CSDA 4C1YA 4UOUA 5H47A 4C1YB 1IUBA 4D4UA 4AGTA 4AGIA 1IUCA 1OFZA 4AHAA 5EO7A 5EO8A
chains in the Genus database with same CATH superfamily
1MS5A 1V3EA 4YZ5A 1IVFA 2F27A 4XHXA 4M4NA 5B2DA 2BATA 4GZWA 2VWDA 1V2IA 4GDJA 4AGIA 1V3BA 3NN9A 3SOQA 5HUNA 5HUKA 1V3CA 5D9CA 3WDZA 4X49A 4M3MA 2F12A 2OJHA 2WOZA 2W38A 1INYA 2GHSA 3S8ZA 4AH4A 4ZGCA 1L7FA 1Q7FA 3B7EA 3II7A 4B7MA 4FP3A 1MWEA 2HQSA 3O9JA 1W20A 1NMAN 2DYHA 1E8TA 4FPOB 3CL2A 3SOBB 2HU4A 4IYGA 2XZIA 2F13A 1V3DA 4XJ8A 2HTQA 3A9GA 1SUUA 3TIBA 4IFJA 4CPOA 4GEZA 3SRGA 2IAPA 2YA5A 2P4OA 3LI4A 4JMLA 2GVXA 1CRZA 2ISMA 2BZDA 4HZXA 4GN9A 2IVZA 4QN3A 1INGA 4FPEA 4WA5A 2XN4A 4XIOA 2GVVA 1S1DA 3A71A 4MWXA 1S18A 1W1XA 2G8SA 3ADEA 1MS4A 4MWVA 4Q6KA 4K1HA 1NSCA 2QE8A 3GVJA 4XMBA 1NCAN 2HT5A 5FZJA 4YZ1A 5HUGA 4B7QA 1RWIA 2W8BB 3H71A 1INFA 1MS9A 2YDPA 3UC1A 1WCQA 4FPGA 2Z32A 1USXA 4HZWA 2IATA 4L7BA 2HT7A 3SREA 4D4UA 1MS3A 2GVUA 1C5KA 4HHQA 1X2JA 4YZ4A 2DSOA 4YW3A 4UF7A 4B7JA 2QWHA 2SILA 4O5SA 2QWGA 1W0OA 5FWWA 3HRPA 4GDIA 2POOA 4CPZA 3SALA 3TI8A 1NPEA 3A72A 1F8CA 1NNBA 4CH9A 4CPMA 3H6JA 3K38A 2AEPA 4FPLA 2ZB6A 4IMBA 5FNUA 3WN7A 3HLHA 5GX4A 1E1AA 2HU0A 3PJQA 2XCYA 3V65B 1XOGA 3FVZA 3K37A 2V91A 4C1YA 2YA8A 2HTRA 4JF7A 5HX0A 1SLLA 2DG1A 3GVKA 1MZ6A 2JKBA 5D9DA 7NN9A 4X4AA 3T1EA 2QWFA 1E8VA 2VSMA 1Z4XA 5GX3A 2YA4A 2BERA 1NCBN 3FW0A 3Q6PA 3Q6KA 4GZQA 4MWYA 3B69A 2GVWA 1Z4WA 4UOUA 4KS1A 3TI5A 2AEQA 4J9TA 2RKCA 4KS3A 3O9KA 2YA7A 1A4QA 4XJUA 4DG6A 2VW0A 4XJWA 2ZZKA 2F11A 2X9MA 5NN9A 1NN2A 5H47A 2SIMA 3SANA 2CMLA 4L7CA 3TICA 1NCCN 3D12A 4IFLX 4FPKA 4X6KA 4KS5A 4BBWA 1W8NA 4L7DA 1Z4ZA 2VVZA 4FQ4A 3K3AA 2C4AA 4MJUA 4B7NA 4XOGA 4GN8A 5D9BA 2W5OA 1CVMA 1INVA 1VCUA 5FZNA 3V1SA 2QWBA 4I00A 1POOA 3ZGCA 3NO0A 4B7RA 2F25A 3INBA 3SLIA 1IVEA 1V0ZA 3A9HA 2F26A 4R40A 4MWRA 2HTWA 3DASA 2HTYA 1V0FA 2W5NA 2ZB5A 1B9VA 1RWLA 5HUMA 4SLIA 2QWJA 2HTVA 1DIMA 4YZ3A 4GB1A 3KGGA 1NMCA 3NSSA 1ZI0A 1F8DA 1CRUA 4C1YB 3K39A 1F8EA 4AHAA 1INXA 4XJ9A 3JU4A 4K1JA 1MZ5A 1A14N 4FOYA 4KS4A 2QWEA 2A75A 4D52A 2IAQA 3TC9A 1U6DX 2C4LA 4H53A 4QN4A 4FPJA 3CL0A 1DILA 3H72A 3KYAA 4K3YA 5GX1A 4YW2A 4IQKA 1N6EA 2VW2A 5FNTA 3G4EA 4M4VA 1N1YA 4FZHA 2VK5A 1QBIA 1N1VA 3W09A 4NC5A 3TI4A 1SNTA 4WEFA 4YW1A 1XOEA 2AH2A 1USRA 3BEQA 4GZTA 1L7GA 1NMBN 4Q1UA 4GNCA 1PJXA 4FOWA 4MJVA 4XE9A 1WP5A 2QWKA 1B9SA 3L6VA 2F10A 2FPCA 1NNCA 4WEGA 4XJZA 1MS1A 3SILA 6NN9A 2SLIA 1B9TA 4QN6A 4DGRA 1IVGA 3S8VA 4HHOA 1NSBA 4XMIA 2BF6A 4N1BA 1ZGKA 1SLIA 4ASCA 4HIZA 2ZWAA 3E5ZA 4XJAA 5EO8A 4GZXA 5EO7A 1Z50A 3DR2A 2FPBA 2IAOA 3VNHA 4YY8A 3CYEA 1W0PA 4GNAA 2VK6A 1INWA 1QLGA 4MWUA 1V0EA 4IN4A 1NCDN 1V04A 4FPCA 4FVKA 2F24A 4KS2A 4GJTA 3VNGA 1NNAA 2IAVA 1IVBA 4NCSA 1K32A 3LI3A 3Q6TA 4MWJA 3TI6A 4YW4A 2IAUA 1IJQA 4HW6A 2IAXA 2QWAA 2B8HA 4XMAA 3K36A 3BYCA 3S94A 5GX2A 4MZAA 2XZJA 4K1IA 3ZGDA 1VCJA 3OPZA 2FHRA 1IVDA 1W8OA 1IVCA 3ALXA 3U0SA 1EURA 4D52B 4FP2A 2W20A 5F9TA 1INHA 3P5BL 4HZVA 5EX7A 2IAWA 3CKZA 4CPLA 3TI3A 3D11A 1Z4YA 3IAXA 4X47A 1S0JA 2HT8A 1E8UA 1WCSA 2HTUA 2XZKA 4FPFA 4CHBA 4ZLRA 5FNRA 2FP9A 4A0PA 1N1SA 1MS0A 4XIKA 1IUCA 1W21A 4M4UA 3LI5A 4XJRA 1EUUA 4GZOA 4MWLA 1MS8A 5F72C 2VAQA 5GTQA 4WA3A 5FNSA 3GVLA 2H2NA 1A4GA 4MZEA 1N6FA 2F29A 4K1KA 4FPYA 3AMSA 3TIAA 2FLUX 4NN9A 4GNBA 4QN5A 3V64C 3H73A 2QWIA 5CGJA 3G4HA 2YDTA 4HZYA 2QWDA 1C9UA 3ALWA 4PWZA 1N7DA 2VSKA 3S2KA 3I1CA 4MX0A 1N6DA 1Z4VA 4XILA 4CPYA 1H6LA 1CQ1A 1F8BA 1NSDA 3WW9A 4IFNX 4YW5A 4FOVA 4MWQA 4GZPA 1KITA 2F28A 2QWCA 4D8SA 4XYXA 1SO7A 2H2UA 1IUBA 4GN7A 3O4PA 5JYYA 4MWWA 2IARA 4QN7A 2FP8A 5B2CA 3SOVA 3WWAA 1L7HA 1BJIA 4XHBA 4GZSA 2W8BA 3AMRA 5M1ZA 5GX5A 2F0ZA 1X2RA 2VPJA 2ZW9A 4G3NA 1EUTA 2DG0A 1S0IA 1EUSA 2IASA 4FOQA 2AGSA 4HZZA 1N1TA 4QNPA 5FNQA 2VK7A 2YA6A 4YZ2A 4D52C 4MC7A 4CSDA 4FJ6A 4H52A 2VW1A 4WA4A 3HLIA 4CPNA 4O5TA 4FPHA 4ZY3A 4AGTA 4XJQA 1OFZA 1MR5A
chains in the Genus database with same CATH topology
4D52A 4D52C 4D52B 4AH4A 4CSDA 4C1YA 4UOUA 5H47A 4C1YB 1IUBA 4D4UA 4AGTA 4AGIA 1IUCA 1OFZA 4AHAA 5EO7A 5EO8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4D52 A;  4D52 C;  4D52 B;  4AH4 A;  4CSD A;  4C1Y A;  4UOU A;  5H47 A;  4C1Y B;  1IUB A;  4D4U A;  4AGT A;  4AGI A;  1IUC A;  1OFZ A;  4AHA A;  5EO7 A;  5EO8 A; 
#chains in the Genus database with same CATH topology
 1MS5 A;  1V3E A;  4YZ5 A;  1IVF A;  2F27 A;  4XHX A;  4M4N A;  5B2D A;  2BAT A;  4GZW A;  2VWD A;  1V2I A;  4GDJ A;  4AGI A;  1V3B A;  3NN9 A;  3SOQ A;  5HUN A;  5HUK A;  1V3C A;  5D9C A;  3WDZ A;  4X49 A;  4M3M A;  2F12 A;  2OJH A;  2WOZ A;  2W38 A;  1INY A;  2GHS A;  3S8Z A;  4AH4 A;  4ZGC A;  1L7F A;  1Q7F A;  3B7E A;  3II7 A;  4B7M A;  4FP3 A;  1MWE A;  2HQS A;  3O9J A;  1W20 A;  1NMA N;  2DYH A;  1E8T A;  4FPO B;  3CL2 A;  3SOB B;  2HU4 A;  4IYG A;  2XZI A;  2F13 A;  1V3D A;  4XJ8 A;  2HTQ A;  3A9G A;  1SUU A;  3TIB A;  4IFJ A;  4CPO A;  4GEZ A;  3SRG A;  2IAP A;  2YA5 A;  2P4O A;  3LI4 A;  4JML A;  2GVX A;  1CRZ A;  2ISM A;  2BZD A;  4HZX A;  4GN9 A;  2IVZ A;  4QN3 A;  1ING A;  4FPE A;  4WA5 A;  2XN4 A;  4XIO A;  2GVV A;  1S1D A;  3A71 A;  4MWX A;  1S18 A;  1W1X A;  2G8S A;  3ADE A;  1MS4 A;  4MWV A;  4Q6K A;  4K1H A;  1NSC A;  2QE8 A;  3GVJ A;  4XMB A;  1NCA N;  2HT5 A;  5FZJ A;  4YZ1 A;  5HUG A;  4B7Q A;  1RWI A;  2W8B B;  3H71 A;  1INF A;  1MS9 A;  2YDP A;  3UC1 A;  1WCQ A;  4FPG A;  2Z32 A;  1USX A;  4HZW A;  2IAT A;  4L7B A;  2HT7 A;  3SRE A;  4D4U A;  1MS3 A;  2GVU A;  1C5K A;  4HHQ A;  1X2J A;  4YZ4 A;  2DSO A;  4YW3 A;  4UF7 A;  4B7J A;  2QWH A;  2SIL A;  4O5S A;  2QWG A;  1W0O A;  5FWW A;  3HRP A;  4GDI A;  2POO A;  4CPZ A;  3SAL A;  3TI8 A;  1NPE A;  3A72 A;  1F8C A;  1NNB A;  4CH9 A;  4CPM A;  3H6J A;  3K38 A;  2AEP A;  4FPL A;  2ZB6 A;  4IMB A;  5FNU A;  3WN7 A;  3HLH A;  5GX4 A;  1E1A A;  2HU0 A;  3PJQ A;  2XCY A;  3V65 B;  1XOG A;  3FVZ A;  3K37 A;  2V91 A;  4C1Y A;  2YA8 A;  2HTR A;  4JF7 A;  5HX0 A;  1SLL A;  2DG1 A;  3GVK A;  1MZ6 A;  2JKB A;  5D9D A;  7NN9 A;  4X4A A;  3T1E A;  2QWF A;  1E8V A;  2VSM A;  1Z4X A;  5GX3 A;  2YA4 A;  2BER A;  1NCB N;  3FW0 A;  3Q6P A;  3Q6K A;  4GZQ A;  4MWY A;  3B69 A;  2GVW A;  1Z4W A;  4UOU A;  4KS1 A;  3TI5 A;  2AEQ A;  4J9T A;  2RKC A;  4KS3 A;  3O9K A;  2YA7 A;  1A4Q A;  4XJU A;  4DG6 A;  2VW0 A;  4XJW A;  2ZZK A;  2F11 A;  2X9M A;  5NN9 A;  1NN2 A;  5H47 A;  2SIM A;  3SAN A;  2CML A;  4L7C A;  3TIC A;  1NCC N;  3D12 A;  4IFL X;  4FPK A;  4X6K A;  4KS5 A;  4BBW A;  1W8N A;  4L7D A;  1Z4Z A;  2VVZ A;  4FQ4 A;  3K3A A;  2C4A A;  4MJU A;  4B7N A;  4XOG A;  4GN8 A;  5D9B A;  2W5O A;  1CVM A;  1INV A;  1VCU A;  5FZN A;  3V1S A;  2QWB A;  4I00 A;  1POO A;  3ZGC A;  3NO0 A;  4B7R A;  2F25 A;  3INB A;  3SLI A;  1IVE A;  1V0Z A;  3A9H A;  2F26 A;  4R40 A;  4MWR A;  2HTW A;  3DAS A;  2HTY A;  1V0F A;  2W5N A;  2ZB5 A;  1B9V A;  1RWL A;  5HUM A;  4SLI A;  2QWJ A;  2HTV A;  1DIM A;  4YZ3 A;  4GB1 A;  3KGG A;  1NMC A;  3NSS A;  1ZI0 A;  1F8D A;  1CRU A;  4C1Y B;  3K39 A;  1F8E A;  4AHA A;  1INX A;  4XJ9 A;  3JU4 A;  4K1J A;  1MZ5 A;  1A14 N;  4FOY A;  4KS4 A;  2QWE A;  2A75 A;  4D52 A;  2IAQ A;  3TC9 A;  1U6D X;  2C4L A;  4H53 A;  4QN4 A;  4FPJ A;  3CL0 A;  1DIL A;  3H72 A;  3KYA A;  4K3Y A;  5GX1 A;  4YW2 A;  4IQK A;  1N6E A;  2VW2 A;  5FNT A;  3G4E A;  4M4V A;  1N1Y A;  4FZH A;  2VK5 A;  1QBI A;  1N1V A;  3W09 A;  4NC5 A;  3TI4 A;  1SNT A;  4WEF A;  4YW1 A;  1XOE A;  2AH2 A;  1USR A;  3BEQ A;  4GZT A;  1L7G A;  1NMB N;  4Q1U A;  4GNC A;  1PJX A;  4FOW A;  4MJV A;  4XE9 A;  1WP5 A;  2QWK A;  1B9S A;  3L6V A;  2F10 A;  2FPC A;  1NNC A;  4WEG A;  4XJZ A;  1MS1 A;  3SIL A;  6NN9 A;  2SLI A;  1B9T A;  4QN6 A;  4DGR A;  1IVG A;  3S8V A;  4HHO A;  1NSB A;  4XMI A;  2BF6 A;  4N1B A;  1ZGK A;  1SLI A;  4ASC A;  4HIZ A;  2ZWA A;  3E5Z A;  4XJA A;  5EO8 A;  4GZX A;  5EO7 A;  1Z50 A;  3DR2 A;  2FPB A;  2IAO A;  3VNH A;  4YY8 A;  3CYE A;  1W0P A;  4GNA A;  2VK6 A;  1INW A;  1QLG A;  4MWU A;  1V0E A;  4IN4 A;  1NCD N;  1V04 A;  4FPC A;  4FVK A;  2F24 A;  4KS2 A;  4GJT A;  3VNG A;  1NNA A;  2IAV A;  1IVB A;  4NCS A;  1K32 A;  3LI3 A;  3Q6T A;  4MWJ A;  3TI6 A;  4YW4 A;  2IAU A;  1IJQ A;  4HW6 A;  2IAX A;  2QWA A;  2B8H A;  4XMA A;  3K36 A;  3BYC A;  3S94 A;  5GX2 A;  4MZA A;  2XZJ A;  4K1I A;  3ZGD A;  1VCJ A;  3OPZ A;  2FHR A;  1IVD A;  1W8O A;  1IVC A;  3ALX A;  3U0S A;  1EUR A;  4D52 B;  4FP2 A;  2W20 A;  5F9T A;  1INH A;  3P5B L;  4HZV A;  5EX7 A;  2IAW A;  3CKZ A;  4CPL A;  3TI3 A;  3D11 A;  1Z4Y A;  3IAX A;  4X47 A;  1S0J A;  2HT8 A;  1E8U A;  1WCS A;  2HTU A;  2XZK A;  4FPF A;  4CHB A;  4ZLR A;  5FNR A;  2FP9 A;  4A0P A;  1N1S A;  1MS0 A;  4XIK A;  1IUC A;  1W21 A;  4M4U A;  3LI5 A;  4XJR A;  1EUU A;  4GZO A;  4MWL A;  1MS8 A;  5F72 C;  2VAQ A;  5GTQ A;  4WA3 A;  5FNS A;  3GVL A;  2H2N A;  1A4G A;  4MZE A;  1N6F A;  2F29 A;  4K1K A;  4FPY A;  3AMS A;  3TIA A;  2FLU X;  4NN9 A;  4GNB A;  4QN5 A;  3V64 C;  3H73 A;  2QWI A;  5CGJ A;  3G4H A;  2YDT A;  4HZY A;  2QWD A;  1C9U A;  3ALW A;  4PWZ A;  1N7D A;  2VSK A;  3S2K A;  3I1C A;  4MX0 A;  1N6D A;  1Z4V A;  4XIL A;  4CPY A;  1H6L A;  1CQ1 A;  1F8B A;  1NSD A;  3WW9 A;  4IFN X;  4YW5 A;  4FOV A;  4MWQ A;  4GZP A;  1KIT A;  2F28 A;  2QWC A;  4D8S A;  4XYX A;  1SO7 A;  2H2U A;  1IUB A;  4GN7 A;  3O4P A;  5JYY A;  4MWW A;  2IAR A;  4QN7 A;  2FP8 A;  5B2C A;  3SOV A;  3WWA A;  1L7H A;  1BJI A;  4XHB A;  4GZS A;  2W8B A;  3AMR A;  5M1Z A;  5GX5 A;  2F0Z A;  1X2R A;  2VPJ A;  2ZW9 A;  4G3N A;  1EUT A;  2DG0 A;  1S0I A;  1EUS A;  2IAS A;  4FOQ A;  2AGS A;  4HZZ A;  1N1T A;  4QNP A;  5FNQ A;  2VK7 A;  2YA6 A;  4YZ2 A;  4D52 C;  4MC7 A;  4CSD A;  4FJ6 A;  4H52 A;  2VW1 A;  4WA4 A;  3HLI A;  4CPN A;  4O5T A;  4FPH A;  4ZY3 A;  4AGT A;  4XJQ A;  1OFZ A;  1MR5 A; 
#chains in the Genus database with same CATH homology
 4D52 A;  4D52 C;  4D52 B;  4AH4 A;  4CSD A;  4C1Y A;  4UOU A;  5H47 A;  4C1Y B;  1IUB A;  4D4U A;  4AGT A;  4AGI A;  1IUC A;  1OFZ A;  4AHA A;  5EO7 A;  5EO8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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