4ASCA

Crystal structure of the kelch domain of human kbtbd5
Total Genus 57
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
308
structure length
307
Chain Sequence
MFLQDLIFMISEEGAVAYDPAANECYASLSSQVPKNHVSLVTKENQVFVAGGLFYNEDNKEDPMSAYFLQFDHLDSEWLGMPPLPSPRCLFGLGEALNSIYVVGGREIKDGERCLDSVMCYDRLSFKWGESDPLPYVVYGHTVLSHMDLVYVIGGKGSDRKCLNKMCVYDPKKFEWKELAPMQTARSLFGATVHDGRIIVAAGVTDTGLTSSAEVYSITDNKWAPFEAFPQERSSLSLVSLVGTLYAIGGFATLETESGELVPTELNDIWRYNEEEKKWEGVLREIAYAAGATFLPVRLNVLRLTKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Basis for Cul3 Assembly with the Btb-Kelch Family of E3 Ubiquitin Ligases.
pubmed doi rcsb
molecule tags Protein binding
source organism Homo sapiens
molecule keywords KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN 5
total genus 57
structure length 307
sequence length 308
ec nomenclature
pdb deposition date 2012-04-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 4ascA00
4XMBA 5CGJA 2DYHA 5FNTA 5FZJA 4ASCA 1X2JA 4IQKA 4L7DA 4ZY3A 3ZGDA 2FLUX 3II7A 4N1BA 4ZGCA 5FZNA 2VPJA 4CH9A 3ZGCA 3VNHA 3WDZA 3WN7A 4L7BA 1X2RA 2WOZA 3ADEA 1ZGKA 5FNUA 4L7CA 4CHBA 2ZW9A 4IFLX 3VNGA 2ZZKA 4YY8A 4IFJA 2XN4A 4IN4A 5F72C 5FNSA 5FNRA 4IFNX 2ZWAA 5FNQA 1U6DX 2Z32A
chains in the Genus database with same CATH superfamily
4GDJA 4FQ4A 4YZ5A 1MZ5A 2GVVA 3SALA 3UC1A 3A71A 5GX2A 4CPNA 1PJXA 4A0PA 1IVGA 4IMBA 1IVCA 2SILA 4X47A 4QN5A 4ZLRA 4YZ1A 1W1XA 4L7BA 7NN9A 1E8VA 4MWRA 4D52C 3A9GA 1NMCA 4XIKA 5HUNA 4MWJA 1CVMA 2XN4A 3L6VA 4CPOA 2AEPA 2IAXA 2RKCA 2VW2A 4XYXA 4BBWA 2QWFA 2ISMA 4HZXA 1L7FA 4AHAA 4FP3A 1L7HA 5FWWA 2HQSA 3FVZA 1V3BA 2W8BA 5HUMA 1QBIA 3E5ZA 2FP9A 4HIZA 1B9TA 3B7EA 4XJ9A 1IUCA 1NSDA 5FNUA 3TI5A 2XZIA 4FPEA 1DILA 3HRPA 4YY8A 2IAUA 2F25A 4Q6KA 4QN7A 4WA5A 4XE9A 5HUKA 1U6DX 3GVLA 1MS4A 6NN9A 2XCYA 3S94A 3A72A 3ALWA 1NNAA 4ASCA 3K38A 3K36A 1N6EA 4FPYA 3SILA 1W0PA 2AH2A 3O4PA 1F8EA 2SLIA 4GZXA 4QN3A 1Z4YA 3P5BL 2YA4A 2QWIA 4WA4A 2ZZKA 3TI6A 2YA6A 3V1SA 1EUTA 4IFNX 2XZKA 4MWQA 2VWDA 4H53A 2IATA 1USXA 3K3AA 3K37A 3WWAA 5FNTA 3NSSA 4MWYA 2QWHA 3A9HA 1F8DA 4Q1UA 3WW9A 4N1BA 1IVDA 4FOVA 4FVKA 1MS5A 2VPJA 4HHQA 5F9TA 5HUGA 3S8ZA 4XJ8A 2F10A 4UF7A 4M4UA 4FPOB 4QNPA 1SLLA 4FP2A 4GZSA 4XHXA 2W5NA 3BYCA 2HTUA 1EURA 2QWBA 4X4AA 3H71A 2C4LA 4NCSA 4FOWA 2HT8A 4GZQA 1NSCA 4L7DA 2HTYA 4MZEA 3T1EA 2FHRA 1NCCN 4O5SA 2G8SA 3VNHA 1A4GA 4GDIA 2BF6A 4G3NA 3ADEA 1B9SA 2YA5A 1ZI0A 4B7RA 3D11A 1INYA 2HU4A 2FP8A 1L7GA 3DASA 2QWKA 3H6JA 4FPCA 2H2UA 2JKBA 2W8BB 4KS1A 1V3DA 5JYYA 4DG6A 2VK6A 4GNAA 4KS2A 4KS5A 2IAWA 3H72A 2FLUX 2H2NA 1W8OA 2F27A 2HT5A 4GNCA 1WCSA 1Z50A 3SRGA 4GZOA 1VCUA 1XOGA 1V0EA 3CL0A 2ZB5A 2ZB6A 5GX1A 2AGSA 1IJQA 2ZWAA 2SIMA 4GZWA 4M4VA 1N1YA 4C1YA 3LI4A 2C4AA 3ALXA 4NN9A 3TI3A 1S0IA 1V0FA 1X2JA 2HTQA 4FPFA 4FJ6A 4GN8A 1NPEA 4CPZA 4HZYA 3TI4A 4AGTA 2YA8A 3S2KA 1Z4XA 3SANA 3INBA 4YW1A 4XJRA 3H73A 3S8VA 4D52A 4KS4A 1SNTA 4PWZA 4MZAA 2QWDA 4YW3A 3OPZA 2BATA 3TIBA 1RWIA 2GVUA 2W20A 2IAVA 4ZY3A 3II7A 5FZNA 1NN2A 1F8BA 4HZZA 4WEGA 4XOGA 3U0SA 4FPJA 1ZGKA 2FPCA 4YZ3A 2YDPA 3AMSA 4HZVA 1IVBA 4MC7A 2VSMA 1XOEA 4HHOA 3W09A 1MS3A 3GVJA 2HT7A 2AEQA 5CGJA 3NO0A 3V64C 3G4HA 1W0OA 5B2DA 1Q7FA 4NC5A 3ZGDA 1N6DA 1IUBA 1WCQA 3AMRA 2VK7A 2QWCA 1SLIA 3SOBB 2W38A 4XJWA 1V0ZA 5GX5A 4GN7A 4CPYA 1MR5A 4FOYA 4K3YA 5GX4A 5F72C 1V2IA 4YW5A 2VAQA 4MWLA 4FPHA 3SLIA 4H52A 2QE8A 2F11A 1SO7A 1VCJA 2V91A 5HX0A 1BJIA 1INXA 4XJQA 2XZJA 1QLGA 5D9CA 1WP5A 4MX0A 4D4UA 2VK5A 1MS8A 3JU4A 4K1IA 4YZ4A 1MZ6A 4GZTA 4YW2A 2CMLA 2X9MA 3HLHA 1NMAN 1V04A 1X2RA 2WOZA 4XJAA 3SOQA 2HTRA 4GEZA 2DG0A 5NN9A 4IFLX 4KS3A 2F24A 4MWXA 1W8NA 1EUUA 1V3CA 4YZ2A 1N1TA 1W20A 1MS9A 3CL2A 5GX3A 1MS0A 4WA3A 2DYHA 4WEFA 3HLIA 4QN6A 3DR2A 3D12A 3SREA 3Q6KA 1CRZA 2GVWA 3NN9A 5D9DA 4B7MA 4B7NA 3O9KA 2VW0A 4GN9A 2QWGA 1NCBN 2QWJA 3FW0A 1IVFA 2ZW9A 3O9JA 2F29A 4XJUA 5FNRA 2P4OA 3WN7A 2Z32A 3IAXA 4XIOA 4XMBA 1A4QA 1Z4ZA 1E8TA 1F8CA 4CPLA 2B8HA 1V3EA 2F12A 2FPBA 2HTWA 4GB1A 3TI8A 1EUSA 2DG1A 4JMLA 3LI5A 4FPKA 3WDZA 1A14N 1S18A 4SLIA 5D9BA 4CHBA 4HZWA 4GJTA 4GNBA 1KITA 4X6KA 4CPMA 2POOA 3KGGA 2QWEA 4K1KA 4XHBA 3I1CA 3CKZA 1NNBA 4O5TA 5EO8A 4XJZA 1MWEA 4J9TA 1S1DA 4K1JA 3TC9A 1W21A 4AGIA 2DSOA 4FPLA 4AH4A 4UOUA 1NCDN 4FOQA 4M3MA 1E1AA 4YW4A 4L7CA 4QN4A 2QWAA 1INVA 2F28A 5FNSA 1H6LA 5FZJA 2GHSA 2IASA 1B9VA 1DIMA 1Z4VA 1E8UA 4MJVA 1NSBA 1SUUA 4D8SA 4B7JA 1INWA 1C9UA 2YA7A 1POOA 4JF7A 1N1VA 4B7QA 5B2CA 4GZPA 2VVZA 2IAOA 4CH9A 1CRUA 4DGRA 1USRA 4HW6A 5H47A 3BEQA 4FZHA 3VNGA 4IFJA 1CQ1A 3CYEA 4CSDA 4MJUA 4MWWA 4K1HA 2F0ZA 5GTQA 1INFA 2HTVA 2F26A 4XMAA 4IYGA 3V65B 3Q6TA 3TIAA 5EO7A 1INGA 2A75A 3B69A 4ZGCA 4FPGA 1N1SA 2IARA 1N6FA 1C5KA 4C1YB 3SOVA 1K32A 3Q6PA 5M1ZA 1N7DA 2VW1A 4IN4A 5FNQA 2IVZA 2OJHA 2BERA 1Z4WA 2F13A 2IAQA 3GVKA 4R40A 1NMBN 3TICA 2HU0A 4IQKA 1RWLA 1NCAN 4M4NA 2W5OA 4D52B 4MWUA 2GVXA 5EX7A 3G4EA 4X49A 3KYAA 1OFZA 2BZDA 2YDTA 3ZGCA 1IVEA 3PJQA 4XMIA 4I00A 1S0JA 3K39A 2IAPA 4MWVA 2VSKA 3LI3A 1MS1A 4XILA 1NNCA 1INHA
chains in the Genus database with same CATH topology
4XMBA 5CGJA 2DYHA 5FNTA 5FZJA 4ASCA 1X2JA 4IQKA 4L7DA 4ZY3A 3ZGDA 2FLUX 3II7A 4N1BA 4ZGCA 5FZNA 2VPJA 4CH9A 3ZGCA 3VNHA 3WDZA 3WN7A 4L7BA 1X2RA 2WOZA 3ADEA 1ZGKA 5FNUA 4L7CA 4CHBA 2ZW9A 4IFLX 3VNGA 2ZZKA 4YY8A 4IFJA 2XN4A 4IN4A 5F72C 5FNSA 5FNRA 4IFNX 2ZWAA 5FNQA 1U6DX 2Z32A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XMB A;  5CGJ A;  2DYH A;  5FNT A;  5FZJ A;  4ASC A;  1X2J A;  4IQK A;  4L7D A;  4ZY3 A;  3ZGD A;  2FLU X;  3II7 A;  4N1B A;  4ZGC A;  5FZN A;  2VPJ A;  4CH9 A;  3ZGC A;  3VNH A;  3WDZ A;  3WN7 A;  4L7B A;  1X2R A;  2WOZ A;  3ADE A;  1ZGK A;  5FNU A;  4L7C A;  4CHB A;  2ZW9 A;  4IFL X;  3VNG A;  2ZZK A;  4YY8 A;  4IFJ A;  2XN4 A;  4IN4 A;  5F72 C;  5FNS A;  5FNR A;  4IFN X;  2ZWA A;  5FNQ A;  1U6D X;  2Z32 A; 
#chains in the Genus database with same CATH topology
 4GDJ A;  4FQ4 A;  4YZ5 A;  1MZ5 A;  2GVV A;  3SAL A;  3UC1 A;  3A71 A;  5GX2 A;  4CPN A;  1PJX A;  4A0P A;  1IVG A;  4IMB A;  1IVC A;  2SIL A;  4X47 A;  4QN5 A;  4ZLR A;  4YZ1 A;  1W1X A;  4L7B A;  7NN9 A;  1E8V A;  4MWR A;  4D52 C;  3A9G A;  1NMC A;  4XIK A;  5HUN A;  4MWJ A;  1CVM A;  2XN4 A;  3L6V A;  4CPO A;  2AEP A;  2IAX A;  2RKC A;  2VW2 A;  4XYX A;  4BBW A;  2QWF A;  2ISM A;  4HZX A;  1L7F A;  4AHA A;  4FP3 A;  1L7H A;  5FWW A;  2HQS A;  3FVZ A;  1V3B A;  2W8B A;  5HUM A;  1QBI A;  3E5Z A;  2FP9 A;  4HIZ A;  1B9T A;  3B7E A;  4XJ9 A;  1IUC A;  1NSD A;  5FNU A;  3TI5 A;  2XZI A;  4FPE A;  1DIL A;  3HRP A;  4YY8 A;  2IAU A;  2F25 A;  4Q6K A;  4QN7 A;  4WA5 A;  4XE9 A;  5HUK A;  1U6D X;  3GVL A;  1MS4 A;  6NN9 A;  2XCY A;  3S94 A;  3A72 A;  3ALW A;  1NNA A;  4ASC A;  3K38 A;  3K36 A;  1N6E A;  4FPY A;  3SIL A;  1W0P A;  2AH2 A;  3O4P A;  1F8E A;  2SLI A;  4GZX A;  4QN3 A;  1Z4Y A;  3P5B L;  2YA4 A;  2QWI A;  4WA4 A;  2ZZK A;  3TI6 A;  2YA6 A;  3V1S A;  1EUT A;  4IFN X;  2XZK A;  4MWQ A;  2VWD A;  4H53 A;  2IAT A;  1USX A;  3K3A A;  3K37 A;  3WWA A;  5FNT A;  3NSS A;  4MWY A;  2QWH A;  3A9H A;  1F8D A;  4Q1U A;  3WW9 A;  4N1B A;  1IVD A;  4FOV A;  4FVK A;  1MS5 A;  2VPJ A;  4HHQ A;  5F9T A;  5HUG A;  3S8Z A;  4XJ8 A;  2F10 A;  4UF7 A;  4M4U A;  4FPO B;  4QNP A;  1SLL A;  4FP2 A;  4GZS A;  4XHX A;  2W5N A;  3BYC A;  2HTU A;  1EUR A;  2QWB A;  4X4A A;  3H71 A;  2C4L A;  4NCS A;  4FOW A;  2HT8 A;  4GZQ A;  1NSC A;  4L7D A;  2HTY A;  4MZE A;  3T1E A;  2FHR A;  1NCC N;  4O5S A;  2G8S A;  3VNH A;  1A4G A;  4GDI A;  2BF6 A;  4G3N A;  3ADE A;  1B9S A;  2YA5 A;  1ZI0 A;  4B7R A;  3D11 A;  1INY A;  2HU4 A;  2FP8 A;  1L7G A;  3DAS A;  2QWK A;  3H6J A;  4FPC A;  2H2U A;  2JKB A;  2W8B B;  4KS1 A;  1V3D A;  5JYY A;  4DG6 A;  2VK6 A;  4GNA A;  4KS2 A;  4KS5 A;  2IAW A;  3H72 A;  2FLU X;  2H2N A;  1W8O A;  2F27 A;  2HT5 A;  4GNC A;  1WCS A;  1Z50 A;  3SRG A;  4GZO A;  1VCU A;  1XOG A;  1V0E A;  3CL0 A;  2ZB5 A;  2ZB6 A;  5GX1 A;  2AGS A;  1IJQ A;  2ZWA A;  2SIM A;  4GZW A;  4M4V A;  1N1Y A;  4C1Y A;  3LI4 A;  2C4A A;  3ALX A;  4NN9 A;  3TI3 A;  1S0I A;  1V0F A;  1X2J A;  2HTQ A;  4FPF A;  4FJ6 A;  4GN8 A;  1NPE A;  4CPZ A;  4HZY A;  3TI4 A;  4AGT A;  2YA8 A;  3S2K A;  1Z4X A;  3SAN A;  3INB A;  4YW1 A;  4XJR A;  3H73 A;  3S8V A;  4D52 A;  4KS4 A;  1SNT A;  4PWZ A;  4MZA A;  2QWD A;  4YW3 A;  3OPZ A;  2BAT A;  3TIB A;  1RWI A;  2GVU A;  2W20 A;  2IAV A;  4ZY3 A;  3II7 A;  5FZN A;  1NN2 A;  1F8B A;  4HZZ A;  4WEG A;  4XOG A;  3U0S A;  4FPJ A;  1ZGK A;  2FPC A;  4YZ3 A;  2YDP A;  3AMS A;  4HZV A;  1IVB A;  4MC7 A;  2VSM A;  1XOE A;  4HHO A;  3W09 A;  1MS3 A;  3GVJ A;  2HT7 A;  2AEQ A;  5CGJ A;  3NO0 A;  3V64 C;  3G4H A;  1W0O A;  5B2D A;  1Q7F A;  4NC5 A;  3ZGD A;  1N6D A;  1IUB A;  1WCQ A;  3AMR A;  2VK7 A;  2QWC A;  1SLI A;  3SOB B;  2W38 A;  4XJW A;  1V0Z A;  5GX5 A;  4GN7 A;  4CPY A;  1MR5 A;  4FOY A;  4K3Y A;  5GX4 A;  5F72 C;  1V2I A;  4YW5 A;  2VAQ A;  4MWL A;  4FPH A;  3SLI A;  4H52 A;  2QE8 A;  2F11 A;  1SO7 A;  1VCJ A;  2V91 A;  5HX0 A;  1BJI A;  1INX A;  4XJQ A;  2XZJ A;  1QLG A;  5D9C A;  1WP5 A;  4MX0 A;  4D4U A;  2VK5 A;  1MS8 A;  3JU4 A;  4K1I A;  4YZ4 A;  1MZ6 A;  4GZT A;  4YW2 A;  2CML A;  2X9M A;  3HLH A;  1NMA N;  1V04 A;  1X2R A;  2WOZ A;  4XJA A;  3SOQ A;  2HTR A;  4GEZ A;  2DG0 A;  5NN9 A;  4IFL X;  4KS3 A;  2F24 A;  4MWX A;  1W8N A;  1EUU A;  1V3C A;  4YZ2 A;  1N1T A;  1W20 A;  1MS9 A;  3CL2 A;  5GX3 A;  1MS0 A;  4WA3 A;  2DYH A;  4WEF A;  3HLI A;  4QN6 A;  3DR2 A;  3D12 A;  3SRE A;  3Q6K A;  1CRZ A;  2GVW A;  3NN9 A;  5D9D A;  4B7M A;  4B7N A;  3O9K A;  2VW0 A;  4GN9 A;  2QWG A;  1NCB N;  2QWJ A;  3FW0 A;  1IVF A;  2ZW9 A;  3O9J A;  2F29 A;  4XJU A;  5FNR A;  2P4O A;  3WN7 A;  2Z32 A;  3IAX A;  4XIO A;  4XMB A;  1A4Q A;  1Z4Z A;  1E8T A;  1F8C A;  4CPL A;  2B8H A;  1V3E A;  2F12 A;  2FPB A;  2HTW A;  4GB1 A;  3TI8 A;  1EUS A;  2DG1 A;  4JML A;  3LI5 A;  4FPK A;  3WDZ A;  1A14 N;  1S18 A;  4SLI A;  5D9B A;  4CHB A;  4HZW A;  4GJT A;  4GNB A;  1KIT A;  4X6K A;  4CPM A;  2POO A;  3KGG A;  2QWE A;  4K1K A;  4XHB A;  3I1C A;  3CKZ A;  1NNB A;  4O5T A;  5EO8 A;  4XJZ A;  1MWE A;  4J9T A;  1S1D A;  4K1J A;  3TC9 A;  1W21 A;  4AGI A;  2DSO A;  4FPL A;  4AH4 A;  4UOU A;  1NCD N;  4FOQ A;  4M3M A;  1E1A A;  4YW4 A;  4L7C A;  4QN4 A;  2QWA A;  1INV A;  2F28 A;  5FNS A;  1H6L A;  5FZJ A;  2GHS A;  2IAS A;  1B9V A;  1DIM A;  1Z4V A;  1E8U A;  4MJV A;  1NSB A;  1SUU A;  4D8S A;  4B7J A;  1INW A;  1C9U A;  2YA7 A;  1POO A;  4JF7 A;  1N1V A;  4B7Q A;  5B2C A;  4GZP A;  2VVZ A;  2IAO A;  4CH9 A;  1CRU A;  4DGR A;  1USR A;  4HW6 A;  5H47 A;  3BEQ A;  4FZH A;  3VNG A;  4IFJ A;  1CQ1 A;  3CYE A;  4CSD A;  4MJU A;  4MWW A;  4K1H A;  2F0Z A;  5GTQ A;  1INF A;  2HTV A;  2F26 A;  4XMA A;  4IYG A;  3V65 B;  3Q6T A;  3TIA A;  5EO7 A;  1ING A;  2A75 A;  3B69 A;  4ZGC A;  4FPG A;  1N1S A;  2IAR A;  1N6F A;  1C5K A;  4C1Y B;  3SOV A;  1K32 A;  3Q6P A;  5M1Z A;  1N7D A;  2VW1 A;  4IN4 A;  5FNQ A;  2IVZ A;  2OJH A;  2BER A;  1Z4W A;  2F13 A;  2IAQ A;  3GVK A;  4R40 A;  1NMB N;  3TIC A;  2HU0 A;  4IQK A;  1RWL A;  1NCA N;  4M4N A;  2W5O A;  4D52 B;  4MWU A;  2GVX A;  5EX7 A;  3G4E A;  4X49 A;  3KYA A;  1OFZ A;  2BZD A;  2YDT A;  3ZGC A;  1IVE A;  3PJQ A;  4XMI A;  4I00 A;  1S0J A;  3K39 A;  2IAP A;  4MWV A;  2VSK A;  3LI3 A;  1MS1 A;  4XIL A;  1NNC A;  1INH A; 
#chains in the Genus database with same CATH homology
 4XMB A;  5CGJ A;  2DYH A;  5FNT A;  5FZJ A;  4ASC A;  1X2J A;  4IQK A;  4L7D A;  4ZY3 A;  3ZGD A;  2FLU X;  3II7 A;  4N1B A;  4ZGC A;  5FZN A;  2VPJ A;  4CH9 A;  3ZGC A;  3VNH A;  3WDZ A;  3WN7 A;  4L7B A;  1X2R A;  2WOZ A;  3ADE A;  1ZGK A;  5FNU A;  4L7C A;  4CHB A;  2ZW9 A;  4IFL X;  3VNG A;  2ZZK A;  4YY8 A;  4IFJ A;  2XN4 A;  4IN4 A;  5F72 C;  5FNS A;  5FNR A;  4IFN X;  2ZWA A;  5FNQ A;  1U6D X;  2Z32 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...