4HHOA

Serum paraoxonase-1 by directed evolution with the h115w mutation
Total Genus 79
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
79
sequence length
336
structure length
326
Chain Sequence
QKSSFQTRFNVHREVTPVELPNCNLVKGIDNGSEDLEILPNGLAFISSGLKKSGKILLMDLNEKEPAVSELEIIGNTLDISSFNPWGISTFIDDDNTVYLLVVNHPGSSSTVEVFKFQEEEKSLLHLKTIRHKLLPSVNDIVAVGPEHFYATNDHYFIDPYLKSWEMHLGLAWSFVTYYSPNDVRVVAEGFDFANGINISPDGKYVYIAELLAHKIHVYEKHANWTLTPLRVLSFDTLVDNISVDPVTGDLWVGCHPNGMRIFFYDAENPPGSEVLRIQDILSEEPKVTVVYAENGTVLQGSTVAAVYKGKLLIGTVFHKALYCDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme.
pubmed doi rcsb
molecule tags Hydrolase
source organism Synthetic construct
molecule keywords SERUM PARAOXONASE BY DIRECTED EVOLUTION
total genus 79
structure length 326
sequence length 336
ec nomenclature ec 3.1.1.2: Arylesterase.
pdb deposition date 2012-10-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.30 Mainly Beta 6 Propeller Neuraminidase TolB, C-terminal domain 4hhoA00
4O5TA 5GX3A 1H6LA 2DSOA 2FP9A 2FPBA 2GVVA 2FPCA 4ZLRA 5D9CA 3V65B 4GNBA 3S94A 1RWIA 2IASA 3P5BL 2GHSA 1V04A 3S8VA 3S8ZA 2IAOA 2OJHA 3LI4A 3LI5A 2IATA 3TC9A 2IAUA 3KYAA 1NPEA 2FP8A 1C9UA 4O5SA 5GTQA 3V64C 2IAXA 3U0SA 4HHQA 4PWZA 3A9GA 2DG1A 3BYCA 1Q7FA 3SREA 2V91A 1C5KA 4HHOA 1CQ1A 2P4OA 2IVZA 4R40A 3FVZA 5D9BA 5D9DA 2DG0A 3WW9A 3G4HA 3WWAA 3HLHA 4HW6A 3S2KA 2GVUA 1PJXA 2W8BB 1N7DA 3HLIA 1QBIA 2GVWA 2IAPA 3AMSA 4GN8A 5GX1A 2W8BA 3SOQA 2VAQA 3O4PA 3FW0A 5GX2A 3SOVA 1CRUA 2IAVA 4GNCA 4IYGA 3Q6PA 5GX4A 3HRPA 4IMBA 3I1CA 4GN7A 4JMLA 1CRZA 1E1AA 2G8SA 1POOA 4Q1UA 2IARA 1CVMA 3SOBB 3KGGA 3LI3A 3DR2A 3Q6TA 2IAWA 3Q6KA 3AMRA 3IAXA 3DASA 5GX5A 5EX7A 2IAQA 4DG6A 3SRGA 5FWWA 2POOA 4GNAA 1IJQA 1QLGA 2QE8A 3G4EA 2GVXA 1RWLA 4GN9A 4A0PA 2HQSA 3A9HA 3E5ZA 3V1SA 2ISMA
chains in the Genus database with same CATH superfamily
1B9VA 1SNTA 1U6DX 4FPLA 4MWJA 1NCCN 5HUMA 3ZGDA 4X49A 4K1KA 1N1VA 1NSBA 2VPJA 1N1TA 1RWIA 2F12A 1NCAN 1MS3A 4M4UA 4GZSA 2ZZKA 3S8VA 1NMAN 3TI5A 2OJHA 3LI5A 4FOVA 2BZDA 2F24A 4O5SA 4M4VA 1NSCA 3V64C 4MWLA 2F11A 4YY8A 1OFZA 3A9GA 4FPHA 3BYCA 3K38A 3GVJA 4H52A 1L7HA 3K37A 4YZ1A 1Q7FA 1NN2A 1IVGA 1INGA 1USRA 1INHA 2V91A 4L7BA 4FPOB 4XJWA 3VNGA 2IVZA 3WDZA 2SLIA 4B7MA 2DG0A 3HLHA 4HW6A 2W38A 4YW5A 3H6JA 1W1XA 2IAPA 2BF6A 2WOZA 3AMSA 4GN8A 1E8UA 4L7CA 1N6EA 2XZIA 6NN9A 2VK6A 4JF7A 1N1YA 3H71A 2QWBA 5FNQA 1CRUA 2F13A 1EURA 4GN7A 3OPZA 2QWGA 4CPLA 1ZI0A 2VW1A 4GB1A 4XOGA 1INXA 1IVEA 1W0OA 4YW3A 1MS5A 4Q1UA 4J9TA 4FVKA 3KGGA 1DIMA 3DASA 2VSKA 4M4NA 5GX5A 4QN4A 4YZ5A 4ZY3A 4DG6A 4B7JA 2F10A 4MC7A 4K1JA 4D4UA 2QE8A 4D52A 4CPOA 3ALXA 4QNPA 5F9TA 2FLUX 1V0EA 5CGJA 4DGRA 3O9JA 4A0PA 1B9SA 1MS4A 3W09A 5JYYA 3V1SA 4C1YB 4O5TA 2DSOA 4FPJA 3T1EA 1A4QA 1V3CA 4K1HA 2FP9A 2GVVA 4FPEA 4ZLRA 4WA3A 4IFNX 2HT8A 4YZ4A 4ASCA 2Z32A 4XYXA 2HTRA 1INYA 1NCDN 2BERA 2GHSA 4GDIA 2W5NA 3ALWA 4FOQA 4MZAA 3TC9A 1C9UA 3U0SA 2IAXA 3PJQA 1X2RA 4HHQA 4KS4A 4FOWA 1WCSA 4QN7A 2QWHA 4XHXA 1IVDA 1W8OA 4XE9A 4FP3A 4FQ4A 1L7GA 4XMBA 4YW4A 2XZJA 2VWDA 3L6VA 1IVFA 2QWAA 4B7RA 2QWCA 5HUNA 2F25A 2HTVA 1L7FA 2C4LA 4MX0A 1MR5A 2YA7A 1CQ1A 2P4OA 1NMCA 3II7A 4CH9A 2JKBA 3O9KA 3TI3A 4HZZA 3WW9A 4GZTA 4XMIA 2W8BB 1N7DA 2GVWA 4MJUA 4KS2A 3CL0A 2SILA 4XJQA 3SALA 7NN9A 2ZWAA 3FW0A 1W8NA 4XIKA 4IFLX 4MWRA 1MS0A 1V0ZA 2QWIA 4GZOA 3K3AA 1F8DA 3HRPA 2CMLA 4JMLA 4YW1A 2C4AA 3GVLA 4FOYA 1N6FA 1MZ6A 2G8SA 3GVKA 4FPYA 4CHBA 1VCJA 4FPKA 4KS1A 4MWVA 2YDPA 4N1BA 2AH2A 3Q6TA 4FJ6A 3Q6KA 3AMRA 3IAXA 4MWUA 4K1IA 3WN7A 1Z4WA 2BATA 4HZYA 3SRGA 5F72C 3TI8A 2F28A 2F29A 5HX0A 1NMBN 1F8EA 1QLGA 2HT5A 3TICA 1MS1A 1INFA 4YW2A 3K39A 1DILA 4GN9A 4GJTA 4AGIA 2HQSA 4IQKA 4XJZA 1XOEA 2W20A 2HTQA 4L7DA 5NN9A 4HZXA 1INVA 5FNSA 5B2CA 3V65B 4GNBA 1W0PA 4GDJA 4XJ8A 4GZWA 2XCYA 4XHBA 2A75A 2H2NA 2IASA 3P5BL 5FNRA 4BBWA 2YDTA 1V04A 3S8ZA 3LI4A 2IATA 1KITA 2DYHA 1SO7A 4X6KA 2FP8A 5GTQA 5B2DA 1V3EA 2DG1A 2XZKA 4FPCA 4ZGCA 3JU4A 4GZXA 2ZB5A 4X4AA 3SREA 2F27A 1IUCA 1Z4XA 1B9TA 2H2UA 3NO0A 4AHAA 2QWKA 2YA8A 3A71A 4IFJA 1NNAA 2ZB6A 3SILA 3FVZA 5D9BA 5D9DA 4G3NA 4SLIA 3ZGCA 4H53A 4GZPA 1BJIA 2SIMA 3G4HA 3NSSA 1IVBA 2B8HA 2VW0A 5FNTA 3WWAA 4AGTA 2HU4A 2AEQA 4FP2A 4XJ9A 3S2KA 1PJXA 1MZ5A 3TI4A 1EUSA 4GEZA 4WEFA 5GX1A 5EO7A 5FNUA 1IVCA 1N1SA 3SOQA 2QWFA 4Q6KA 2RKCA 3B7EA 3TI6A 5HUKA 3O4PA 1N6DA 4CPNA 4GNCA 4I00A 4IYGA 3SANA 4IMBA 3I1CA 1F8CA 3H73A 4CPZA 2VK5A 4KS5A 4HIZA 1S0JA 4MWQA 2IARA 1CVMA 4QN5A 1E8TA 3NN9A 4CSDA 4AH4A 2HTUA 3LI3A 1V0FA 3DR2A 3TIBA 2IAWA 5FZJA 4WEGA 1USXA 2F26A 1NNBA 2HT7A 4D52B 1V3BA 1A4GA 1S0IA 3TIAA 1NNCA 3CL2A 4K3YA 4D8SA 2GVXA 2YA5A 3INBA 1RWLA 4GZQA 4MWXA 3A9HA 3E5ZA 1IUBA 1K32A 4XMAA 4XIOA 1Z4ZA 5GX3A 1H6LA 5HUGA 4B7QA 1A14N 2FPBA 4C1YA 2FHRA 1SUUA 2FPCA 5D9CA 4KS3A 4WA5A 3S94A 2VVZA 4QN3A 3B69A 1VCUA 1INWA 3D11A 1ZGKA 3D12A 2QWEA 1W21A 2IAOA 2AGSA 1Z4VA 2IAUA 4M3MA 3KYAA 1NPEA 4B7NA 2AEPA 4MZEA 4PWZA 4HZWA 4XJAA 4YZ3A 4FZHA 4NCSA 4FPFA 1C5KA 4NC5A 4X47A 4HHOA 4YZ2A 2XN4A 3ADEA 2YA4A 4QN6A 4R40A 1NSDA 4XJUA 4CPMA 4WA4A 1EUUA 1Z50A 4D52C 1SLIA 2HTYA 2YA6A 2GVUA 5H47A 3HLIA 1E8VA 1QBIA 1WCQA 3A72A 4XJRA 2QWDA 4IN4A 3CKZA 1WP5A 5FZNA 2W8BA 2QWJA 2VAQA 1MS9A 4MWYA 1SLLA 4FPGA 5GX2A 3SLIA 3SOVA 2IAVA 5EO8A 3BEQA 3Q6PA 5GX4A 1S1DA 4NN9A 1CRZA 4CPYA 1E1AA 1POOA 4HZVA 3H72A 2X9MA 2ZW9A 4UOUA 3K36A 1V2IA 1EUTA 3SOBB 1F8BA 4MJVA 1W20A 2VSMA 4XILA 5M1ZA 3UC1A 4MWWA 1S18A 4UF7A 1MS8A 1NCBN 5EX7A 1Z4YA 1X2JA 2IAQA 2VW2A 1XOGA 5FWWA 2POOA 2VK7A 2HTWA 4GNAA 2W5OA 1IJQA 3G4EA 3CYEA 2HU0A 1MWEA 1V3DA 2ISMA 2F0ZA 3VNHA
chains in the Genus database with same CATH topology
4O5TA 5GX3A 1H6LA 2DSOA 2FP9A 2FPBA 2GVVA 2FPCA 4ZLRA 5D9CA 3V65B 4GNBA 3S94A 1RWIA 2IASA 3P5BL 2GHSA 1V04A 3S8VA 3S8ZA 2IAOA 2OJHA 3LI4A 3LI5A 2IATA 3TC9A 2IAUA 3KYAA 1NPEA 2FP8A 1C9UA 4O5SA 5GTQA 3V64C 2IAXA 3U0SA 4HHQA 4PWZA 3A9GA 2DG1A 3BYCA 1Q7FA 3SREA 2V91A 1C5KA 4HHOA 1CQ1A 2P4OA 2IVZA 4R40A 3FVZA 5D9BA 5D9DA 2DG0A 3WW9A 3G4HA 3WWAA 3HLHA 4HW6A 3S2KA 2GVUA 1PJXA 2W8BB 1N7DA 3HLIA 1QBIA 2GVWA 2IAPA 3AMSA 4GN8A 5GX1A 2W8BA 3SOQA 2VAQA 3O4PA 3FW0A 5GX2A 3SOVA 1CRUA 2IAVA 4GNCA 4IYGA 3Q6PA 5GX4A 3HRPA 4IMBA 3I1CA 4GN7A 4JMLA 1CRZA 1E1AA 2G8SA 1POOA 4Q1UA 2IARA 1CVMA 3SOBB 3KGGA 3LI3A 3DR2A 3Q6TA 2IAWA 3Q6KA 3AMRA 3IAXA 3DASA 5GX5A 5EX7A 2IAQA 4DG6A 3SRGA 5FWWA 2POOA 4GNAA 1IJQA 1QLGA 2QE8A 3G4EA 2GVXA 1RWLA 4GN9A 4A0PA 2HQSA 3A9HA 3E5ZA 3V1SA 2ISMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O5T A;  5GX3 A;  1H6L A;  2DSO A;  2FP9 A;  2FPB A;  2GVV A;  2FPC A;  4ZLR A;  5D9C A;  3V65 B;  4GNB A;  3S94 A;  1RWI A;  2IAS A;  3P5B L;  2GHS A;  1V04 A;  3S8V A;  3S8Z A;  2IAO A;  2OJH A;  3LI4 A;  3LI5 A;  2IAT A;  3TC9 A;  2IAU A;  3KYA A;  1NPE A;  2FP8 A;  1C9U A;  4O5S A;  5GTQ A;  3V64 C;  2IAX A;  3U0S A;  4HHQ A;  4PWZ A;  3A9G A;  2DG1 A;  3BYC A;  1Q7F A;  3SRE A;  2V91 A;  1C5K A;  4HHO A;  1CQ1 A;  2P4O A;  2IVZ A;  4R40 A;  3FVZ A;  5D9B A;  5D9D A;  2DG0 A;  3WW9 A;  3G4H A;  3WWA A;  3HLH A;  4HW6 A;  3S2K A;  2GVU A;  1PJX A;  2W8B B;  1N7D A;  3HLI A;  1QBI A;  2GVW A;  2IAP A;  3AMS A;  4GN8 A;  5GX1 A;  2W8B A;  3SOQ A;  2VAQ A;  3O4P A;  3FW0 A;  5GX2 A;  3SOV A;  1CRU A;  2IAV A;  4GNC A;  4IYG A;  3Q6P A;  5GX4 A;  3HRP A;  4IMB A;  3I1C A;  4GN7 A;  4JML A;  1CRZ A;  1E1A A;  2G8S A;  1POO A;  4Q1U A;  2IAR A;  1CVM A;  3SOB B;  3KGG A;  3LI3 A;  3DR2 A;  3Q6T A;  2IAW A;  3Q6K A;  3AMR A;  3IAX A;  3DAS A;  5GX5 A;  5EX7 A;  2IAQ A;  4DG6 A;  3SRG A;  5FWW A;  2POO A;  4GNA A;  1IJQ A;  1QLG A;  2QE8 A;  3G4E A;  2GVX A;  1RWL A;  4GN9 A;  4A0P A;  2HQS A;  3A9H A;  3E5Z A;  3V1S A;  2ISM A; 
#chains in the Genus database with same CATH topology
 1B9V A;  1SNT A;  1U6D X;  4FPL A;  4MWJ A;  1NCC N;  5HUM A;  3ZGD A;  4X49 A;  4K1K A;  1N1V A;  1NSB A;  2VPJ A;  1N1T A;  1RWI A;  2F12 A;  1NCA N;  1MS3 A;  4M4U A;  4GZS A;  2ZZK A;  3S8V A;  1NMA N;  3TI5 A;  2OJH A;  3LI5 A;  4FOV A;  2BZD A;  2F24 A;  4O5S A;  4M4V A;  1NSC A;  3V64 C;  4MWL A;  2F11 A;  4YY8 A;  1OFZ A;  3A9G A;  4FPH A;  3BYC A;  3K38 A;  3GVJ A;  4H52 A;  1L7H A;  3K37 A;  4YZ1 A;  1Q7F A;  1NN2 A;  1IVG A;  1ING A;  1USR A;  1INH A;  2V91 A;  4L7B A;  4FPO B;  4XJW A;  3VNG A;  2IVZ A;  3WDZ A;  2SLI A;  4B7M A;  2DG0 A;  3HLH A;  4HW6 A;  2W38 A;  4YW5 A;  3H6J A;  1W1X A;  2IAP A;  2BF6 A;  2WOZ A;  3AMS A;  4GN8 A;  1E8U A;  4L7C A;  1N6E A;  2XZI A;  6NN9 A;  2VK6 A;  4JF7 A;  1N1Y A;  3H71 A;  2QWB A;  5FNQ A;  1CRU A;  2F13 A;  1EUR A;  4GN7 A;  3OPZ A;  2QWG A;  4CPL A;  1ZI0 A;  2VW1 A;  4GB1 A;  4XOG A;  1INX A;  1IVE A;  1W0O A;  4YW3 A;  1MS5 A;  4Q1U A;  4J9T A;  4FVK A;  3KGG A;  1DIM A;  3DAS A;  2VSK A;  4M4N A;  5GX5 A;  4QN4 A;  4YZ5 A;  4ZY3 A;  4DG6 A;  4B7J A;  2F10 A;  4MC7 A;  4K1J A;  4D4U A;  2QE8 A;  4D52 A;  4CPO A;  3ALX A;  4QNP A;  5F9T A;  2FLU X;  1V0E A;  5CGJ A;  4DGR A;  3O9J A;  4A0P A;  1B9S A;  1MS4 A;  3W09 A;  5JYY A;  3V1S A;  4C1Y B;  4O5T A;  2DSO A;  4FPJ A;  3T1E A;  1A4Q A;  1V3C A;  4K1H A;  2FP9 A;  2GVV A;  4FPE A;  4ZLR A;  4WA3 A;  4IFN X;  2HT8 A;  4YZ4 A;  4ASC A;  2Z32 A;  4XYX A;  2HTR A;  1INY A;  1NCD N;  2BER A;  2GHS A;  4GDI A;  2W5N A;  3ALW A;  4FOQ A;  4MZA A;  3TC9 A;  1C9U A;  3U0S A;  2IAX A;  3PJQ A;  1X2R A;  4HHQ A;  4KS4 A;  4FOW A;  1WCS A;  4QN7 A;  2QWH A;  4XHX A;  1IVD A;  1W8O A;  4XE9 A;  4FP3 A;  4FQ4 A;  1L7G A;  4XMB A;  4YW4 A;  2XZJ A;  2VWD A;  3L6V A;  1IVF A;  2QWA A;  4B7R A;  2QWC A;  5HUN A;  2F25 A;  2HTV A;  1L7F A;  2C4L A;  4MX0 A;  1MR5 A;  2YA7 A;  1CQ1 A;  2P4O A;  1NMC A;  3II7 A;  4CH9 A;  2JKB A;  3O9K A;  3TI3 A;  4HZZ A;  3WW9 A;  4GZT A;  4XMI A;  2W8B B;  1N7D A;  2GVW A;  4MJU A;  4KS2 A;  3CL0 A;  2SIL A;  4XJQ A;  3SAL A;  7NN9 A;  2ZWA A;  3FW0 A;  1W8N A;  4XIK A;  4IFL X;  4MWR A;  1MS0 A;  1V0Z A;  2QWI A;  4GZO A;  3K3A A;  1F8D A;  3HRP A;  2CML A;  4JML A;  4YW1 A;  2C4A A;  3GVL A;  4FOY A;  1N6F A;  1MZ6 A;  2G8S A;  3GVK A;  4FPY A;  4CHB A;  1VCJ A;  4FPK A;  4KS1 A;  4MWV A;  2YDP A;  4N1B A;  2AH2 A;  3Q6T A;  4FJ6 A;  3Q6K A;  3AMR A;  3IAX A;  4MWU A;  4K1I A;  3WN7 A;  1Z4W A;  2BAT A;  4HZY A;  3SRG A;  5F72 C;  3TI8 A;  2F28 A;  2F29 A;  5HX0 A;  1NMB N;  1F8E A;  1QLG A;  2HT5 A;  3TIC A;  1MS1 A;  1INF A;  4YW2 A;  3K39 A;  1DIL A;  4GN9 A;  4GJT A;  4AGI A;  2HQS A;  4IQK A;  4XJZ A;  1XOE A;  2W20 A;  2HTQ A;  4L7D A;  5NN9 A;  4HZX A;  1INV A;  5FNS A;  5B2C A;  3V65 B;  4GNB A;  1W0P A;  4GDJ A;  4XJ8 A;  4GZW A;  2XCY A;  4XHB A;  2A75 A;  2H2N A;  2IAS A;  3P5B L;  5FNR A;  4BBW A;  2YDT A;  1V04 A;  3S8Z A;  3LI4 A;  2IAT A;  1KIT A;  2DYH A;  1SO7 A;  4X6K A;  2FP8 A;  5GTQ A;  5B2D A;  1V3E A;  2DG1 A;  2XZK A;  4FPC A;  4ZGC A;  3JU4 A;  4GZX A;  2ZB5 A;  4X4A A;  3SRE A;  2F27 A;  1IUC A;  1Z4X A;  1B9T A;  2H2U A;  3NO0 A;  4AHA A;  2QWK A;  2YA8 A;  3A71 A;  4IFJ A;  1NNA A;  2ZB6 A;  3SIL A;  3FVZ A;  5D9B A;  5D9D A;  4G3N A;  4SLI A;  3ZGC A;  4H53 A;  4GZP A;  1BJI A;  2SIM A;  3G4H A;  3NSS A;  1IVB A;  2B8H A;  2VW0 A;  5FNT A;  3WWA A;  4AGT A;  2HU4 A;  2AEQ A;  4FP2 A;  4XJ9 A;  3S2K A;  1PJX A;  1MZ5 A;  3TI4 A;  1EUS A;  4GEZ A;  4WEF A;  5GX1 A;  5EO7 A;  5FNU A;  1IVC A;  1N1S A;  3SOQ A;  2QWF A;  4Q6K A;  2RKC A;  3B7E A;  3TI6 A;  5HUK A;  3O4P A;  1N6D A;  4CPN A;  4GNC A;  4I00 A;  4IYG A;  3SAN A;  4IMB A;  3I1C A;  1F8C A;  3H73 A;  4CPZ A;  2VK5 A;  4KS5 A;  4HIZ A;  1S0J A;  4MWQ A;  2IAR A;  1CVM A;  4QN5 A;  1E8T A;  3NN9 A;  4CSD A;  4AH4 A;  2HTU A;  3LI3 A;  1V0F A;  3DR2 A;  3TIB A;  2IAW A;  5FZJ A;  4WEG A;  1USX A;  2F26 A;  1NNB A;  2HT7 A;  4D52 B;  1V3B A;  1A4G A;  1S0I A;  3TIA A;  1NNC A;  3CL2 A;  4K3Y A;  4D8S A;  2GVX A;  2YA5 A;  3INB A;  1RWL A;  4GZQ A;  4MWX A;  3A9H A;  3E5Z A;  1IUB A;  1K32 A;  4XMA A;  4XIO A;  1Z4Z A;  5GX3 A;  1H6L A;  5HUG A;  4B7Q A;  1A14 N;  2FPB A;  4C1Y A;  2FHR A;  1SUU A;  2FPC A;  5D9C A;  4KS3 A;  4WA5 A;  3S94 A;  2VVZ A;  4QN3 A;  3B69 A;  1VCU A;  1INW A;  3D11 A;  1ZGK A;  3D12 A;  2QWE A;  1W21 A;  2IAO A;  2AGS A;  1Z4V A;  2IAU A;  4M3M A;  3KYA A;  1NPE A;  4B7N A;  2AEP A;  4MZE A;  4PWZ A;  4HZW A;  4XJA A;  4YZ3 A;  4FZH A;  4NCS A;  4FPF A;  1C5K A;  4NC5 A;  4X47 A;  4HHO A;  4YZ2 A;  2XN4 A;  3ADE A;  2YA4 A;  4QN6 A;  4R40 A;  1NSD A;  4XJU A;  4CPM A;  4WA4 A;  1EUU A;  1Z50 A;  4D52 C;  1SLI A;  2HTY A;  2YA6 A;  2GVU A;  5H47 A;  3HLI A;  1E8V A;  1QBI A;  1WCQ A;  3A72 A;  4XJR A;  2QWD A;  4IN4 A;  3CKZ A;  1WP5 A;  5FZN A;  2W8B A;  2QWJ A;  2VAQ A;  1MS9 A;  4MWY A;  1SLL A;  4FPG A;  5GX2 A;  3SLI A;  3SOV A;  2IAV A;  5EO8 A;  3BEQ A;  3Q6P A;  5GX4 A;  1S1D A;  4NN9 A;  1CRZ A;  4CPY A;  1E1A A;  1POO A;  4HZV A;  3H72 A;  2X9M A;  2ZW9 A;  4UOU A;  3K36 A;  1V2I A;  1EUT A;  3SOB B;  1F8B A;  4MJV A;  1W20 A;  2VSM A;  4XIL A;  5M1Z A;  3UC1 A;  4MWW A;  1S18 A;  4UF7 A;  1MS8 A;  1NCB N;  5EX7 A;  1Z4Y A;  1X2J A;  2IAQ A;  2VW2 A;  1XOG A;  5FWW A;  2POO A;  2VK7 A;  2HTW A;  4GNA A;  2W5O A;  1IJQ A;  3G4E A;  3CYE A;  2HU0 A;  1MWE A;  1V3D A;  2ISM A;  2F0Z A;  3VNH A; 
#chains in the Genus database with same CATH homology
 4O5T A;  5GX3 A;  1H6L A;  2DSO A;  2FP9 A;  2FPB A;  2GVV A;  2FPC A;  4ZLR A;  5D9C A;  3V65 B;  4GNB A;  3S94 A;  1RWI A;  2IAS A;  3P5B L;  2GHS A;  1V04 A;  3S8V A;  3S8Z A;  2IAO A;  2OJH A;  3LI4 A;  3LI5 A;  2IAT A;  3TC9 A;  2IAU A;  3KYA A;  1NPE A;  2FP8 A;  1C9U A;  4O5S A;  5GTQ A;  3V64 C;  2IAX A;  3U0S A;  4HHQ A;  4PWZ A;  3A9G A;  2DG1 A;  3BYC A;  1Q7F A;  3SRE A;  2V91 A;  1C5K A;  4HHO A;  1CQ1 A;  2P4O A;  2IVZ A;  4R40 A;  3FVZ A;  5D9B A;  5D9D A;  2DG0 A;  3WW9 A;  3G4H A;  3WWA A;  3HLH A;  4HW6 A;  3S2K A;  2GVU A;  1PJX A;  2W8B B;  1N7D A;  3HLI A;  1QBI A;  2GVW A;  2IAP A;  3AMS A;  4GN8 A;  5GX1 A;  2W8B A;  3SOQ A;  2VAQ A;  3O4P A;  3FW0 A;  5GX2 A;  3SOV A;  1CRU A;  2IAV A;  4GNC A;  4IYG A;  3Q6P A;  5GX4 A;  3HRP A;  4IMB A;  3I1C A;  4GN7 A;  4JML A;  1CRZ A;  1E1A A;  2G8S A;  1POO A;  4Q1U A;  2IAR A;  1CVM A;  3SOB B;  3KGG A;  3LI3 A;  3DR2 A;  3Q6T A;  2IAW A;  3Q6K A;  3AMR A;  3IAX A;  3DAS A;  5GX5 A;  5EX7 A;  2IAQ A;  4DG6 A;  3SRG A;  5FWW A;  2POO A;  4GNA A;  1IJQ A;  1QLG A;  2QE8 A;  3G4E A;  2GVX A;  1RWL A;  4GN9 A;  4A0P A;  2HQS A;  3A9H A;  3E5Z A;  3V1S A;  2ISM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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