4IFJA

Crystal structures of apo keap1, keap1-peptide, and keap1-compound complexes
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
288
structure length
288
Chain Sequence
PKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQVPRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCAPMSVPRNRIGVGVIDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDGTNRLNSAECYYPERNEWRMITAMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVETETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTRMTSGRSGVGVAVT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal Structures of apo Keap1, Keap1-peptide, and Keap1-compound complexes
rcsb
molecule tags Transcription
source organism Homo sapiens
molecule keywords Kelch-like ECH-associated protein 1
total genus 68
structure length 288
sequence length 288
ec nomenclature
pdb deposition date 2012-12-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01344 Kelch_1 Kelch motif
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.80 Mainly Beta 6 Propeller Neuraminidase Kelch-type beta propeller 4ifjA00
4L7CA 3ZGCA 1X2JA 4N1BA 3VNHA 5FNUA 4IQKA 1U6DX 3WN7A 1X2RA 4IFJA 3ADEA 4CH9A 3ZGDA 4IFNX 2FLUX 4YY8A 5F72C 2Z32A 4XMBA 5FZNA 4ZY3A 2ZWAA 5FNRA 4CHBA 2WOZA 4ZGCA 3WDZA 3II7A 4ASCA 2ZW9A 2DYHA 5FNTA 5FZJA 5CGJA 5FNSA 2ZZKA 4L7DA 4L7BA 3VNGA 5FNQA 2VPJA 4IFLX 2XN4A 4IN4A 1ZGKA
chains in the Genus database with same CATH superfamily
3ZGCA 3K36A 4KS2A 2XCYA 4YZ5A 3ADEA 2IAOA 3Q6PA 4YW2A 1POOA 3II7A 2IARA 1A4QA 3FVZA 4B7JA 3TI5A 1MS4A 1SNTA 3L6VA 2ZZKA 1CQ1A 1Q7FA 1E8UA 4GNAA 4XOGA 3GVLA 3O9KA 5B2DA 3LI4A 4H52A 4B7MA 2HU4A 2F0ZA 4FJ6A 1NSBA 1MS3A 4I00A 1CRZA 3HRPA 1V0ZA 3UC1A 2W20A 2ZWAA 2WOZA 4IMBA 2ZW9A 3Q6KA 4FOQA 2B8HA 2W5NA 3WWAA 3VNGA 1V3BA 1C9UA 4X4AA 4FPCA 4X47A 1IJQA 4XHXA 4FPHA 4SLIA 3LI3A 4NN9A 4MC7A 4MZEA 5NN9A 1MZ6A 3TIBA 4CH9A 4D52A 5HUNA 3TI6A 3DR2A 4YY8A 4XMBA 2QE8A 1E1AA 3JU4A 2BF6A 3CYEA 4HZYA 4YZ1A 4YZ4A 1INXA 1WCSA 1Z4VA 1EUSA 5FNSA 2DSOA 4L7DA 2XZJA 2QWIA 2IAPA 2HT8A 2X9MA 4C1YA 3GVKA 1IVBA 4MWUA 5EX7A 1NNBA 1E8TA 5GTQA 4BBWA 1B9SA 4K1HA 2HTQA 2DG0A 2QWAA 2SLIA 4IFJA 2XZKA 5JYYA 4C1YB 4XE9A 2FLUX 2IAXA 5F72C 3IAXA 1N1VA 4CHBA 1CRUA 3H72A 4ZGCA 3GVJA 4GEZA 4NC5A 4B7QA 1W1XA 2YDTA 2F12A 2AGSA 4L7BA 2QWEA 4ZLRA 1W8NA 1IVGA 1IVDA 4MWJA 2XN4A 2GVXA 4XMAA 3O4PA 2BERA 2VAQA 2QWHA 1X2JA 3A71A 5FNUA 5HUGA 4GDJA 3WN7A 3K37A 1F8CA 3TICA 4IFNX 3WW9A 2F11A 4KS5A 1EUUA 1L7GA 5D9CA 2QWFA 1EURA 1V04A 4XJQA 3SRGA 1F8BA 1IUBA 1VCJA 4FQ4A 3TI8A 2VPJA 1INGA 2YA6A 1V3EA 3ALWA 3S8VA 2FHRA 4IN4A 4XYXA 5EO7A 5FWWA 3TC9A 2VK7A 2DG1A 4X6KA 4YW4A 2W8BA 1X2RA 4CSDA 1S0IA 4XJZA 1MS5A 3H71A 4R40A 2FPCA 4GJTA 5B2CA 5FNRA 3TI4A 4PWZA 1RWIA 2QWGA 2QWCA 1MWEA 5EO8A 6NN9A 5D9DA 2CMLA 2IAWA 1INYA 1PJXA 3P5BL 4D52C 4H53A 3V1SA 2F28A 4AHAA 3SALA 4QN6A 4GNCA 4YW3A 4AGTA 3B7EA 2BATA 3D11A 4FP2A 1NN2A 4O5TA 2ZB6A 4FOWA 7NN9A 1SLLA 1NSCA 4WA4A 4XHBA 5FZJA 3A9HA 3CL0A 1NMCA 1USRA 1F8DA 1N7DA 2IAVA 2POOA 4MWLA 3E5ZA 1NMAN 4AH4A 1F8EA 2G8SA 3DASA 3AMRA 3G4EA 4L7CA 4WEFA 2ISMA 3SOVA 3D12A 4QNPA 1V0FA 5GX1A 4K1JA 1N6FA 3OPZA 3BYCA 2Z32A 2GVUA 4FP3A 4KS3A 4XILA 5FZNA 4FPFA 1Z4YA 1MZ5A 4XJ8A 4GN9A 1IVEA 4UOUA 2HTRA 1WP5A 4GN8A 4HZWA 2C4AA 4UF7A 2VSMA 3Q6TA 4B7NA 3O9JA 1A14N 4D52B 4FPKA 1N1YA 1BJIA 1Z4XA 2JKBA 4XMIA 2IAUA 2HQSA 1ZGKA 1DIMA 4HHQA 3U0SA 2F10A 4MWWA 4QN7A 2XZIA 4CPMA 1L7FA 1XOGA 2SIMA 4FPOB 3ALXA 4XJRA 2VW2A 3S94A 4GZWA 1S0JA 2F24A 1Z4WA 1V2IA 1V0EA 4FPJA 5CGJA 2BZDA 4WA3A 3SLIA 3NO0A 4YZ3A 3AMSA 1VCUA 4GN7A 4YW5A 2QWJA 3WDZA 4WEGA 4QN4A 2IATA 3VNHA 2AH2A 4K1KA 4XJAA 1U6DX 4G3NA 4XJWA 3I1CA 2VK6A 3HLIA 2YA5A 1SLIA 4MJUA 1B9TA 1W0PA 5M1ZA 4M3MA 1XOEA 4FVKA 2DYHA 4DG6A 3H73A 4D4UA 2RKCA 1NSDA 1INWA 1IVFA 4B7RA 2VW1A 1NNCA 4MWXA 2IVZA 3K39A 3V65B 4FPEA 4GNBA 3W09A 4A0PA 4CPZA 4MJVA 1NCCN 4GDIA 1B9VA 1SO7A 4FPYA 5HX0A 2W8BB 4IYGA 4GZQA 4GZOA 4YW1A 2W38A 4CPYA 2OJHA 1W20A 2QWDA 3SREA 2VVZA 5F9TA 4N1BA 3LI5A 4GZTA 1W0OA 1W8OA 3KGGA 1E8VA 4MZAA 1CVMA 1SUUA 2H2UA 5H47A 2F27A 4AGIA 2HTVA 1DILA 5HUKA 2GVVA 5HUMA 2H2NA 2P4OA 4J9TA 2F25A 1MR5A 4QN5A 1IVCA 1V3CA 4MWYA 2HT7A 5FNQA 2HTUA 4HIZA 1L7HA 4D8SA 3A9GA 3TI3A 2AEPA 3B69A 2GVWA 3SOBB 4DGRA 4YZ2A 1Z4ZA 1QLGA 4HZXA 3INBA 3HLHA 3SANA 2F13A 3V64C 4HHOA 1A4GA 3NN9A 4GZSA 2YA4A 3CL2A 1V3DA 1NPEA 4O5SA 3G4HA 2F29A 2FP9A 1N1TA 4JF7A 3CKZA 1OFZA 2VWDA 1W21A 2FP8A 2VSKA 2F26A 2YA7A 3A72A 4HZZA 3ZGDA 4GZPA 2QWBA 5GX2A 4ZY3A 1C5KA 2YA8A 4XJUA 4KS1A 4ASCA 4HW6A 4KS4A 5FNTA 4XIOA 4CPOA 1NCBN 2C4LA 4FPLA 4GZXA 4WA5A 3SILA 4K1IA 4M4NA 3K38A 1MS1A 3TIAA 4XIKA 1MS8A 4IFLX 4NCSA 4FPGA 4XJ9A 4M4UA 1N1SA 1RWLA 4MWRA 1NMBN 3FW0A 3PJQA 1INHA 2SILA 1IUCA 4MWVA 1S1DA 2W5OA 1USXA 4QN3A 1EUTA 4CPNA 1WCQA 1S18A 4M4VA 4K3YA 1INFA 1MS0A 2FPBA 4FOYA 5GX3A 3NSSA 2IAQA 3S2KA 1Z50A 3H6JA 3SOQA 4FZHA 1H6LA 4MX0A 4GB1A 4IQKA 4Q6KA 3KYAA 4CPLA 3BEQA 2QWKA 2VW0A 1N6EA 2YDPA 4JMLA 1QBIA 1KITA 1N6DA 4MWQA 1NCDN 2HTYA 2HTWA 2IASA 5GX5A 1INVA 3T1EA 2AEQA 5D9BA 2A75A 3S8ZA 5GX4A 4Q1UA 3K3AA 1MS9A 2HU0A 2VK5A 2V91A 2ZB5A 4FOVA 4HZVA 1K32A 1NNAA 4X49A 2HT5A 1NCAN 2GHSA 1ZI0A
chains in the Genus database with same CATH topology
4L7CA 3ZGCA 1X2JA 4N1BA 3VNHA 5FNUA 4IQKA 1U6DX 3WN7A 1X2RA 4IFJA 3ADEA 4CH9A 3ZGDA 4IFNX 2FLUX 4YY8A 5F72C 2Z32A 4XMBA 5FZNA 4ZY3A 2ZWAA 5FNRA 4CHBA 2WOZA 4ZGCA 3WDZA 3II7A 4ASCA 2ZW9A 2DYHA 5FNTA 5FZJA 5CGJA 5FNSA 2ZZKA 4L7DA 4L7BA 3VNGA 5FNQA 2VPJA 4IFLX 2XN4A 4IN4A 1ZGKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4L7C A;  3ZGC A;  1X2J A;  4N1B A;  3VNH A;  5FNU A;  4IQK A;  1U6D X;  3WN7 A;  1X2R A;  4IFJ A;  3ADE A;  4CH9 A;  3ZGD A;  4IFN X;  2FLU X;  4YY8 A;  5F72 C;  2Z32 A;  4XMB A;  5FZN A;  4ZY3 A;  2ZWA A;  5FNR A;  4CHB A;  2WOZ A;  4ZGC A;  3WDZ A;  3II7 A;  4ASC A;  2ZW9 A;  2DYH A;  5FNT A;  5FZJ A;  5CGJ A;  5FNS A;  2ZZK A;  4L7D A;  4L7B A;  3VNG A;  5FNQ A;  2VPJ A;  4IFL X;  2XN4 A;  4IN4 A;  1ZGK A; 
#chains in the Genus database with same CATH topology
 3ZGC A;  3K36 A;  4KS2 A;  2XCY A;  4YZ5 A;  3ADE A;  2IAO A;  3Q6P A;  4YW2 A;  1POO A;  3II7 A;  2IAR A;  1A4Q A;  3FVZ A;  4B7J A;  3TI5 A;  1MS4 A;  1SNT A;  3L6V A;  2ZZK A;  1CQ1 A;  1Q7F A;  1E8U A;  4GNA A;  4XOG A;  3GVL A;  3O9K A;  5B2D A;  3LI4 A;  4H52 A;  4B7M A;  2HU4 A;  2F0Z A;  4FJ6 A;  1NSB A;  1MS3 A;  4I00 A;  1CRZ A;  3HRP A;  1V0Z A;  3UC1 A;  2W20 A;  2ZWA A;  2WOZ A;  4IMB A;  2ZW9 A;  3Q6K A;  4FOQ A;  2B8H A;  2W5N A;  3WWA A;  3VNG A;  1V3B A;  1C9U A;  4X4A A;  4FPC A;  4X47 A;  1IJQ A;  4XHX A;  4FPH A;  4SLI A;  3LI3 A;  4NN9 A;  4MC7 A;  4MZE A;  5NN9 A;  1MZ6 A;  3TIB A;  4CH9 A;  4D52 A;  5HUN A;  3TI6 A;  3DR2 A;  4YY8 A;  4XMB A;  2QE8 A;  1E1A A;  3JU4 A;  2BF6 A;  3CYE A;  4HZY A;  4YZ1 A;  4YZ4 A;  1INX A;  1WCS A;  1Z4V A;  1EUS A;  5FNS A;  2DSO A;  4L7D A;  2XZJ A;  2QWI A;  2IAP A;  2HT8 A;  2X9M A;  4C1Y A;  3GVK A;  1IVB A;  4MWU A;  5EX7 A;  1NNB A;  1E8T A;  5GTQ A;  4BBW A;  1B9S A;  4K1H A;  2HTQ A;  2DG0 A;  2QWA A;  2SLI A;  4IFJ A;  2XZK A;  5JYY A;  4C1Y B;  4XE9 A;  2FLU X;  2IAX A;  5F72 C;  3IAX A;  1N1V A;  4CHB A;  1CRU A;  3H72 A;  4ZGC A;  3GVJ A;  4GEZ A;  4NC5 A;  4B7Q A;  1W1X A;  2YDT A;  2F12 A;  2AGS A;  4L7B A;  2QWE A;  4ZLR A;  1W8N A;  1IVG A;  1IVD A;  4MWJ A;  2XN4 A;  2GVX A;  4XMA A;  3O4P A;  2BER A;  2VAQ A;  2QWH A;  1X2J A;  3A71 A;  5FNU A;  5HUG A;  4GDJ A;  3WN7 A;  3K37 A;  1F8C A;  3TIC A;  4IFN X;  3WW9 A;  2F11 A;  4KS5 A;  1EUU A;  1L7G A;  5D9C A;  2QWF A;  1EUR A;  1V04 A;  4XJQ A;  3SRG A;  1F8B A;  1IUB A;  1VCJ A;  4FQ4 A;  3TI8 A;  2VPJ A;  1ING A;  2YA6 A;  1V3E A;  3ALW A;  3S8V A;  2FHR A;  4IN4 A;  4XYX A;  5EO7 A;  5FWW A;  3TC9 A;  2VK7 A;  2DG1 A;  4X6K A;  4YW4 A;  2W8B A;  1X2R A;  4CSD A;  1S0I A;  4XJZ A;  1MS5 A;  3H71 A;  4R40 A;  2FPC A;  4GJT A;  5B2C A;  5FNR A;  3TI4 A;  4PWZ A;  1RWI A;  2QWG A;  2QWC A;  1MWE A;  5EO8 A;  6NN9 A;  5D9D A;  2CML A;  2IAW A;  1INY A;  1PJX A;  3P5B L;  4D52 C;  4H53 A;  3V1S A;  2F28 A;  4AHA A;  3SAL A;  4QN6 A;  4GNC A;  4YW3 A;  4AGT A;  3B7E A;  2BAT A;  3D11 A;  4FP2 A;  1NN2 A;  4O5T A;  2ZB6 A;  4FOW A;  7NN9 A;  1SLL A;  1NSC A;  4WA4 A;  4XHB A;  5FZJ A;  3A9H A;  3CL0 A;  1NMC A;  1USR A;  1F8D A;  1N7D A;  2IAV A;  2POO A;  4MWL A;  3E5Z A;  1NMA N;  4AH4 A;  1F8E A;  2G8S A;  3DAS A;  3AMR A;  3G4E A;  4L7C A;  4WEF A;  2ISM A;  3SOV A;  3D12 A;  4QNP A;  1V0F A;  5GX1 A;  4K1J A;  1N6F A;  3OPZ A;  3BYC A;  2Z32 A;  2GVU A;  4FP3 A;  4KS3 A;  4XIL A;  5FZN A;  4FPF A;  1Z4Y A;  1MZ5 A;  4XJ8 A;  4GN9 A;  1IVE A;  4UOU A;  2HTR A;  1WP5 A;  4GN8 A;  4HZW A;  2C4A A;  4UF7 A;  2VSM A;  3Q6T A;  4B7N A;  3O9J A;  1A14 N;  4D52 B;  4FPK A;  1N1Y A;  1BJI A;  1Z4X A;  2JKB A;  4XMI A;  2IAU A;  2HQS A;  1ZGK A;  1DIM A;  4HHQ A;  3U0S A;  2F10 A;  4MWW A;  4QN7 A;  2XZI A;  4CPM A;  1L7F A;  1XOG A;  2SIM A;  4FPO B;  3ALX A;  4XJR A;  2VW2 A;  3S94 A;  4GZW A;  1S0J A;  2F24 A;  1Z4W A;  1V2I A;  1V0E A;  4FPJ A;  5CGJ A;  2BZD A;  4WA3 A;  3SLI A;  3NO0 A;  4YZ3 A;  3AMS A;  1VCU A;  4GN7 A;  4YW5 A;  2QWJ A;  3WDZ A;  4WEG A;  4QN4 A;  2IAT A;  3VNH A;  2AH2 A;  4K1K A;  4XJA A;  1U6D X;  4G3N A;  4XJW A;  3I1C A;  2VK6 A;  3HLI A;  2YA5 A;  1SLI A;  4MJU A;  1B9T A;  1W0P A;  5M1Z A;  4M3M A;  1XOE A;  4FVK A;  2DYH A;  4DG6 A;  3H73 A;  4D4U A;  2RKC A;  1NSD A;  1INW A;  1IVF A;  4B7R A;  2VW1 A;  1NNC A;  4MWX A;  2IVZ A;  3K39 A;  3V65 B;  4FPE A;  4GNB A;  3W09 A;  4A0P A;  4CPZ A;  4MJV A;  1NCC N;  4GDI A;  1B9V A;  1SO7 A;  4FPY A;  5HX0 A;  2W8B B;  4IYG A;  4GZQ A;  4GZO A;  4YW1 A;  2W38 A;  4CPY A;  2OJH A;  1W20 A;  2QWD A;  3SRE A;  2VVZ A;  5F9T A;  4N1B A;  3LI5 A;  4GZT A;  1W0O A;  1W8O A;  3KGG A;  1E8V A;  4MZA A;  1CVM A;  1SUU A;  2H2U A;  5H47 A;  2F27 A;  4AGI A;  2HTV A;  1DIL A;  5HUK A;  2GVV A;  5HUM A;  2H2N A;  2P4O A;  4J9T A;  2F25 A;  1MR5 A;  4QN5 A;  1IVC A;  1V3C A;  4MWY A;  2HT7 A;  5FNQ A;  2HTU A;  4HIZ A;  1L7H A;  4D8S A;  3A9G A;  3TI3 A;  2AEP A;  3B69 A;  2GVW A;  3SOB B;  4DGR A;  4YZ2 A;  1Z4Z A;  1QLG A;  4HZX A;  3INB A;  3HLH A;  3SAN A;  2F13 A;  3V64 C;  4HHO A;  1A4G A;  3NN9 A;  4GZS A;  2YA4 A;  3CL2 A;  1V3D A;  1NPE A;  4O5S A;  3G4H A;  2F29 A;  2FP9 A;  1N1T A;  4JF7 A;  3CKZ A;  1OFZ A;  2VWD A;  1W21 A;  2FP8 A;  2VSK A;  2F26 A;  2YA7 A;  3A72 A;  4HZZ A;  3ZGD A;  4GZP A;  2QWB A;  5GX2 A;  4ZY3 A;  1C5K A;  2YA8 A;  4XJU A;  4KS1 A;  4ASC A;  4HW6 A;  4KS4 A;  5FNT A;  4XIO A;  4CPO A;  1NCB N;  2C4L A;  4FPL A;  4GZX A;  4WA5 A;  3SIL A;  4K1I A;  4M4N A;  3K38 A;  1MS1 A;  3TIA A;  4XIK A;  1MS8 A;  4IFL X;  4NCS A;  4FPG A;  4XJ9 A;  4M4U A;  1N1S A;  1RWL A;  4MWR A;  1NMB N;  3FW0 A;  3PJQ A;  1INH A;  2SIL A;  1IUC A;  4MWV A;  1S1D A;  2W5O A;  1USX A;  4QN3 A;  1EUT A;  4CPN A;  1WCQ A;  1S18 A;  4M4V A;  4K3Y A;  1INF A;  1MS0 A;  2FPB A;  4FOY A;  5GX3 A;  3NSS A;  2IAQ A;  3S2K A;  1Z50 A;  3H6J A;  3SOQ A;  4FZH A;  1H6L A;  4MX0 A;  4GB1 A;  4IQK A;  4Q6K A;  3KYA A;  4CPL A;  3BEQ A;  2QWK A;  2VW0 A;  1N6E A;  2YDP A;  4JML A;  1QBI A;  1KIT A;  1N6D A;  4MWQ A;  1NCD N;  2HTY A;  2HTW A;  2IAS A;  5GX5 A;  1INV A;  3T1E A;  2AEQ A;  5D9B A;  2A75 A;  3S8Z A;  5GX4 A;  4Q1U A;  3K3A A;  1MS9 A;  2HU0 A;  2VK5 A;  2V91 A;  2ZB5 A;  4FOV A;  4HZV A;  1K32 A;  1NNA A;  4X49 A;  2HT5 A;  1NCA N;  2GHS A;  1ZI0 A; 
#chains in the Genus database with same CATH homology
 4L7C A;  3ZGC A;  1X2J A;  4N1B A;  3VNH A;  5FNU A;  4IQK A;  1U6D X;  3WN7 A;  1X2R A;  4IFJ A;  3ADE A;  4CH9 A;  3ZGD A;  4IFN X;  2FLU X;  4YY8 A;  5F72 C;  2Z32 A;  4XMB A;  5FZN A;  4ZY3 A;  2ZWA A;  5FNR A;  4CHB A;  2WOZ A;  4ZGC A;  3WDZ A;  3II7 A;  4ASC A;  2ZW9 A;  2DYH A;  5FNT A;  5FZJ A;  5CGJ A;  5FNS A;  2ZZK A;  4L7D A;  4L7B A;  3VNG A;  5FNQ A;  2VPJ A;  4IFL X;  2XN4 A;  4IN4 A;  1ZGK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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