5JYYA

Structure-based tetravalent zanamivir with potent inhibitory activity against drug-resistant influenza viruses
Total Genus 122
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
122
sequence length
388
structure length
388
Chain Sequence
RNFNNLTKGLCTINSWHIYGKDNAVRIGESSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKSRMSICISGPNNNASAVVWYNRRPVAEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPADTRIYYFKEGKILKWESLTGTAKHIEECSCYGERTGITCTCKDNWQGSNRPVIQIDPVAMTHTSQYICSPVLTDNPRPNDPNIGKCNDPYPGNNNNGVKGFSYLDGANTWLGRTISTASRSGYEMLKVPNALTDDRSKPIQGQTIVLNADWSGYSGSFMDYWAEGDCYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure-Based Tetravalent Zanamivir with Potent Inhibitory Activity against Drug-Resistant Influenza Viruses
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Influenza a virus
molecule keywords Neuraminidase
total genus 122
structure length 388
sequence length 388
ec nomenclature ec 3.2.1.18: Exo-alpha-sialidase.
pdb deposition date 2016-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00064 Neur Neuraminidase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.120.10.10 Mainly Beta 6 Propeller Neuraminidase Neuraminidase 5jyyA00
2VK5A 4FPLA 5HUGA 1INVA 3A71A 4MJUA 3TI8A 1W8NA 4J9TA 3CL2A 1EUUA 3W09A 1N1YA 4X47A 4GZPA 2F10A 4HZZA 4MWRA 2QWCA 4MJVA 2HTYA 3TI6A 2QWFA 4GZOA 4WA4A 1INYA 4B7RA 4MZAA 1A14N 1E8UA 1NNCA 4GJTA 4YZ1A 4K1JA 1W0PA 4FVKA 4YW2A 1NMAN 4FPGA 1NMBN 4MWWA 4XILA 4WEFA 2HT5A 3SLIA 2C4AA 4MC7A 1DIMA 3ALWA 4FPFA 3TIBA 3O9JA 5B2CA 2VWDA 4GZSA 2F25A 4SLIA 2VSKA 1B9TA 1W21A 2RKCA 7NN9A 4XJWA 3CYEA 4GZTA 3A72A 2W5NA 4KS1A 2W20A 2HT7A 1INXA 1KITA 4KS3A 2X9MA 1F8EA 4XIKA 3K3AA 5NN9A 4B7NA 2VK6A 4YW5A 2QWDA 4YW1A 4XJQA 1Z4ZA 2SIMA 4FPYA 4XMAA 1V0EA 2VK7A 4FOYA 1V3CA 3NSSA 4GB1A 4MWYA 3TIAA 1IVBA 5F9TA 4KS5A 2QWEA 4B7QA 4HIZA 4XHXA 2XZIA 1N1TA 1E8VA 1IVEA 1NNAA 1SNTA 1W20A 1A4QA 2F0ZA 3OPZA 4H53A 3H73A 4FPEA 6NN9A 3JU4A 2QWJA 1NCCN 1L7HA 2VW0A 3SANA 1NSDA 1USRA 1MR5A 3GVJA 3TI4A 3GVKA 3TI5A 2F26A 4M4UA 1NMCA 5HUNA 2SLIA 3K39A 4XJZA 5HUMA 3D11A 4D8SA 1INGA 4QN5A 2QWAA 1VCUA 2SILA 3INBA 1DILA 4FOWA 4X49A 4FJ6A 4XMIA 4KS2A 2QWKA 2BERA 1MS9A 2HU4A 2YA7A 3K37A 4GEZA 1INHA 4YZ4A 1V2IA 4HZXA 1N1VA 2YA6A 5M1ZA 4K3YA 1MWEA 2VSMA 4K1HA 2XCYA 1EUTA 2B8HA 4M3MA 4XJ9A 4B7MA 2HTRA 1SLLA 1Z4YA 2XZJA 4NC5A 5JYYA 4MWXA 4FOVA 5HX0A 2AH2A 3K36A 4JF7A 2XZKA 1L7GA 2JKBA 4DGRA 4GDJA 1S0JA 2HTUA 2FHRA 1W1XA 4XJAA 4I00A 4CPLA 4Q6KA 1IVFA 3SALA 1INFA 1MS4A 4CPZA 2ZB5A 2QWHA 4WEGA 2AEPA 1WCQA 1MS1A 3H71A 3B7EA 4CPNA 1F8CA 4XJRA 4NCSA 4QNPA 1V0FA 1Z50A 4FPOB 1XOGA 1IVDA 4UF7A 4MZEA 4XHBA 4CPMA 4QN6A 2F24A 4M4VA 1NCAN 4K1KA 2F13A 1Z4XA 1USXA 4QN3A 1EUSA 2BZDA 4CPYA 2F27A 4XE9A 1NSBA 5HUKA 1NNBA 1MS8A 3CKZA 4MWUA 2HTVA 4HZWA 4FP2A 4WA5A 4GZQA 2YDPA 3T1EA 4FPCA 1SO7A 1N1SA 3GVLA 2YA5A 4FOQA 1NN2A 1VCJA 4MWVA 3BEQA 1B9SA 2ZB6A 4QN4A 2F28A 2W38A 1MS0A 2C4LA 4HZYA 1F8DA 1MZ6A 2QWIA 1XOEA 4GZWA 1V0ZA 1NCDN 1S0IA 4XYXA 2F11A 2VW2A 3H72A 4MX0A 4XJUA 1NSCA 1W0OA 2VVZA 4XIOA 4XJ8A 2W5OA 3ALXA 2HT8A 1Z4VA 4FPKA 3TICA 2A75A 1MS3A 4WA3A 3O9KA 4CPOA 1V3EA 4X4AA 2BF6A 1BJIA 4YW4A 2F29A 1V3DA 1EURA 2AEQA 4MWQA 3B69A 4XOGA 2F12A 1L7FA 2HU0A 3PJQA 4FZHA 4M4NA 4FQ4A 2HTQA 4HZVA 4MWLA 4X6KA 1NCBN 1V3BA 4FPJA 2QWGA 4BBWA 4FPHA 1A4GA 3K38A 4K1IA 4MWJA 2VW1A 1IVCA 1MZ5A 1B9VA 2HTWA 3CL0A 3SILA 2BATA 4YW3A 1SLIA 4GDIA 3H6JA 4B7JA 3TI3A 1IVGA 2YA8A 3D12A 2CMLA 4YZ2A 1Z4WA 2QWBA 1E8TA 1INWA 1WCSA 1MS5A 2YDTA 4H52A 4YZ5A 4YZ3A 4QN7A 4GZXA 1W8OA 4FP3A 2AGSA 4NN9A 2YA4A 4KS4A 1F8BA 5B2DA 3NN9A
chains in the Genus database with same CATH superfamily
2VK5A 4FPLA 4UOUA 5FWWA 5HUGA 3S2KA 1INVA 2IATA 3A9GA 3A71A 4PWZA 3E5ZA 4D4UA 4MJUA 3TI8A 1SUUA 1W8NA 4J9TA 3CL2A 1EUUA 3W09A 1N1YA 4X47A 1V04A 4GZPA 3WW9A 2F10A 4HZZA 4MWRA 4ASCA 5GX3A 2QWCA 3ZGCA 4MJVA 2HTYA 3TI6A 3BYCA 2QWFA 4GZOA 4WA4A 1INYA 4B7RA 4MZAA 1A14N 2GVXA 1E8UA 1NNCA 4GJTA 3O4PA 1N7DA 4YZ1A 3SOQA 4K1JA 1W0PA 4FVKA 2QE8A 4YW2A 1CVMA 1NMAN 4DG6A 4FPGA 1NMBN 5GX2A 4MWWA 4XILA 2IASA 4WEFA 2HT5A 3WDZA 2DYHA 3SLIA 2C4AA 4MC7A 4AGTA 1DIMA 3ALWA 4FPFA 3TIBA 3O9JA 5B2CA 4IFJA 4L7DA 2FP8A 2H2UA 1RWIA 2VWDA 3L6VA 4GZSA 4O5SA 2F25A 4SLIA 2VSKA 1B9TA 4GNBA 1W21A 3Q6TA 2RKCA 2GVUA 2VPJA 7NN9A 4HW6A 4XJWA 3CYEA 1S18A 4GZTA 3A72A 4L7CA 4Q1UA 2W5NA 4KS1A 2W20A 4AH4A 2HT7A 4CHBA 2IAXA 1INXA 1KITA 4KS3A 2X9MA 4L7BA 1F8EA 4N1BA 4XIKA 3K3AA 5NN9A 4B7NA 2VK6A 4A0PA 4YW5A 2QWDA 4YW1A 4XJQA 1Z4ZA 2SIMA 4FPYA 4XMAA 1V0EA 2VK7A 4FOYA 4IFNX 1V3CA 3NSSA 4GB1A 4MWYA 1ZGKA 3TIAA 2GVVA 1IVBA 5GX4A 2POOA 2IVZA 3FVZA 5F9TA 4KS5A 2QWEA 2OJHA 4B7QA 2IAVA 4HIZA 2IAOA 2WOZA 3S94A 1N6DA 4XHXA 2XZIA 1N1TA 1E8VA 1IVEA 3SOBB 1NNAA 1SNTA 1W20A 1A4QA 2F0ZA 3OPZA 1NPEA 4H53A 3H73A 4FPEA 6NN9A 3JU4A 2QWJA 1NCCN 3FW0A 1L7HA 2VW0A 5GX5A 3SANA 1NSDA 1USRA 1MR5A 3A9HA 3GVJA 3TI4A 3GVKA 3TI5A 2F26A 3HLIA 4M4UA 3ZGDA 1NMCA 5HUNA 2SLIA 3K39A 4XJZA 4CH9A 1C5KA 5HUMA 4YY8A 3D11A 4D8SA 1INGA 5D9CA 3G4HA 4QN5A 2QWAA 1VCUA 2SILA 3INBA 1DILA 4D52B 4FOWA 4X49A 4FJ6A 4XMIA 4AHAA 1S1DA 4KS2A 2QWKA 1CRUA 2ZWAA 2BERA 1MS9A 2HU4A 4HHQA 4JMLA 2YA7A 2FP9A 4IN4A 1X2JA 3K37A 4GEZA 1INHA 5EO8A 4YZ4A 1V2IA 4HZXA 1N1VA 2YA6A 5M1ZA 3S8ZA 4K3YA 1MWEA 2VSMA 4K1HA 2XCYA 1EUTA 2B8HA 4M3MA 4XJ9A 1QLGA 2GHSA 4B7MA 4XMBA 3DR2A 5GTQA 2HTRA 1CRZA 4GNAA 3WWAA 1SLLA 1OFZA 3S8VA 1Z4YA 2XZJA 4NC5A 4GN9A 5JYYA 4MWXA 4FOVA 4C1YA 4AGIA 3LI5A 1X2RA 5HX0A 3U0SA 4D52C 2AH2A 3K36A 3NO0A 1ZI0A 4JF7A 2W8BA 2XZKA 1QBIA 1L7GA 2DG0A 1CQ1A 2JKBA 3SRGA 4DGRA 4GDJA 1S0JA 2HTUA 2FHRA 1W1XA 4XJAA 2FLUX 4I00A 4CPLA 4Q6KA 1IVFA 3SALA 5FNSA 1POOA 1INFA 1MS4A 4CPZA 2ZB5A 4IYGA 2QWHA 4WEGA 2AEPA 1WCQA 3IAXA 1MS1A 3H71A 3B7EA 4CSDA 4CPNA 4R40A 5D9BA 1F8CA 1C9UA 4XJRA 2ZZKA 4NCSA 4QNPA 4GN8A 1V0FA 1Z50A 3LI4A 4FPOB 2IAQA 1XOGA 1IVDA 2IAPA 4G3NA 4UF7A 1H6LA 4MZEA 3Q6KA 3HRPA 4XHBA 4CPMA 4GN7A 4QN6A 3V1SA 3LI3A 2F24A 4M4VA 5EX7A 2VAQA 1NCAN 4K1KA 2F13A 1Z4XA 2FPCA 1USXA 4QN3A 1EUSA 2BZDA 3AMSA 5FZNA 2XN4A 4CPYA 2F27A 4XE9A 3V64C 1NSBA 2DG1A 5EO7A 5HUKA 1NNBA 1MS8A 5FNQA 3I1CA 3CKZA 4MWUA 2IAUA 2GVWA 2HTVA 2V91A 4IQKA 4HZWA 1WP5A 4FP2A 3P5BL 4WA5A 3DASA 4GZQA 3WN7A 2YDPA 3T1EA 4FPCA 4ZY3A 1SO7A 1RWLA 3AMRA 1N1SA 4ZGCA 4IFLX 3GVLA 2YA5A 4FOQA 1NN2A 5F72C 1VCJA 4MWVA 3BEQA 1B9SA 3ADEA 2ZB6A 2ZW9A 4QN4A 5FNUA 2F28A 2W38A 3TC9A 3VNHA 1MS0A 2IARA 2H2NA 5H47A 4HHOA 2IAWA 2C4LA 4HZYA 1F8DA 5FNTA 1MZ6A 2QWIA 1XOEA 3VNGA 4GZWA 1V0ZA 1NCDN 1S0IA 4XYXA 2F11A 2VW2A 1N6EA 3H72A 4MX0A 4XJUA 1NSCA 1W0OA 2VVZA 4XIOA 4XJ8A 2W5OA 3SREA 3ALXA 2HT8A 1Z4VA 3II7A 4FPKA 3TICA 1E1AA 1IJQA 3Q6PA 2A75A 1MS3A 4WA3A 3O9KA 5FZJA 1V3EA 4CPOA 4X4AA 2BF6A 1BJIA 4YW4A 3KGGA 2F29A 1V3DA 1EURA 2AEQA 4MWQA 3B69A 4XOGA 2F12A 5D9DA 1L7FA 2HU0A 3PJQA 4FZHA 1Q7FA 3V65B 1N6FA 4M4NA 4FQ4A 5GX1A 2HTQA 1IUCA 4HZVA 4MWLA 3UC1A 4X6KA 3HLHA 1NCBN 1V3BA 2ISMA 4FPJA 2QWGA 4BBWA 4FPHA 1A4GA 3K38A 4K1IA 4MWJA 4O5TA 2VW1A 1IVCA 1MZ5A 2HQSA 1B9VA 4D52A 2HTWA 3CL0A 4C1YB 1K32A 2BATA 2P4OA 4YW3A 3SILA 1SLIA 4GDIA 3SOVA 3H6JA 4B7JA 2FPBA 3TI3A 1IVGA 2YA8A 3D12A 3G4EA 2CMLA 2W8BB 4YZ2A 5CGJA 1Z4WA 2QWBA 1E8TA 1INWA 2Z32A 5FNRA 2G8SA 4ZLRA 1WCSA 1MS5A 2YDTA 4H52A 4YZ5A 4YZ3A 3KYAA 4QN7A 4GZXA 1W8OA 4FP3A 4GNCA 4IMBA 1IUBA 2AGSA 4NN9A 1U6DX 2YA4A 1PJXA 4KS4A 2DSOA 1F8BA 5B2DA 3NN9A
chains in the Genus database with same CATH topology
2VK5A 4FPLA 5HUGA 1INVA 3A71A 4MJUA 3TI8A 1W8NA 4J9TA 3CL2A 1EUUA 3W09A 1N1YA 4X47A 4GZPA 2F10A 4HZZA 4MWRA 2QWCA 4MJVA 2HTYA 3TI6A 2QWFA 4GZOA 4WA4A 1INYA 4B7RA 4MZAA 1A14N 1E8UA 1NNCA 4GJTA 4YZ1A 4K1JA 1W0PA 4FVKA 4YW2A 1NMAN 4FPGA 1NMBN 4MWWA 4XILA 4WEFA 2HT5A 3SLIA 2C4AA 4MC7A 1DIMA 3ALWA 4FPFA 3TIBA 3O9JA 5B2CA 2H2UA 2VWDA 4GZSA 2F25A 4SLIA 2VSKA 1B9TA 1W21A 2RKCA 7NN9A 4XJWA 3CYEA 1S18A 4GZTA 3A72A 2W5NA 4KS1A 2W20A 2HT7A 1INXA 1KITA 4KS3A 2X9MA 1F8EA 4XIKA 3K3AA 5NN9A 4B7NA 2VK6A 4YW5A 2QWDA 4YW1A 4XJQA 1Z4ZA 2SIMA 4FPYA 4XMAA 1V0EA 2VK7A 4FOYA 1V3CA 3NSSA 4GB1A 4MWYA 3TIAA 1IVBA 5F9TA 4KS5A 2QWEA 4B7QA 4HIZA 4XHXA 2XZIA 1N1TA 1E8VA 1IVEA 1NNAA 1SNTA 1W20A 1A4QA 2F0ZA 3OPZA 4H53A 3H73A 4FPEA 6NN9A 3JU4A 2QWJA 1NCCN 1L7HA 2VW0A 3SANA 1NSDA 1USRA 1MR5A 3GVJA 3TI4A 3GVKA 3TI5A 2F26A 4M4UA 1NMCA 5HUNA 2SLIA 3K39A 4XJZA 5HUMA 3D11A 4D8SA 1INGA 4QN5A 2QWAA 1VCUA 2SILA 3INBA 1DILA 4FOWA 4X49A 4FJ6A 4XMIA 1S1DA 4KS2A 2QWKA 2BERA 1MS9A 2HU4A 2YA7A 3K37A 4GEZA 1INHA 4YZ4A 1V2IA 4HZXA 1N1VA 2YA6A 5M1ZA 4K3YA 1MWEA 2VSMA 4K1HA 2XCYA 1EUTA 2B8HA 4M3MA 4XJ9A 4B7MA 2HTRA 1SLLA 1Z4YA 2XZJA 4NC5A 5JYYA 4MWXA 4FOVA 5HX0A 2AH2A 3K36A 4JF7A 2XZKA 1L7GA 2JKBA 4DGRA 4GDJA 1S0JA 2HTUA 2FHRA 1W1XA 4XJAA 4I00A 4CPLA 4Q6KA 1IVFA 3SALA 1INFA 1MS4A 4CPZA 2ZB5A 2QWHA 4WEGA 2AEPA 1WCQA 1MS1A 3H71A 3B7EA 4CPNA 1F8CA 4XJRA 4NCSA 4QNPA 1V0FA 1Z50A 4FPOB 1XOGA 1IVDA 4UF7A 4MZEA 4XHBA 4CPMA 4QN6A 2F24A 4M4VA 1NCAN 4K1KA 2F13A 1Z4XA 1USXA 4QN3A 1EUSA 2BZDA 4CPYA 2F27A 4XE9A 1NSBA 5HUKA 1NNBA 1MS8A 3CKZA 4MWUA 2HTVA 4HZWA 4FP2A 4WA5A 4GZQA 2YDPA 3T1EA 4FPCA 1SO7A 1N1SA 3GVLA 2YA5A 4FOQA 1NN2A 1VCJA 4MWVA 3BEQA 1B9SA 2ZB6A 4QN4A 2F28A 2W38A 1MS0A 2H2NA 2C4LA 4HZYA 1F8DA 1MZ6A 2QWIA 1XOEA 4GZWA 1V0ZA 1NCDN 1S0IA 4XYXA 2F11A 2VW2A 3H72A 4MX0A 4XJUA 1NSCA 1W0OA 2VVZA 4XIOA 4XJ8A 2W5OA 3ALXA 2HT8A 1Z4VA 4FPKA 3TICA 2A75A 1MS3A 4WA3A 3O9KA 4CPOA 1V3EA 4X4AA 2BF6A 1BJIA 4YW4A 2F29A 1V3DA 1EURA 2AEQA 4MWQA 3B69A 4XOGA 2F12A 1L7FA 2HU0A 3PJQA 4FZHA 4M4NA 4FQ4A 2HTQA 4HZVA 4MWLA 4X6KA 1NCBN 1V3BA 4FPJA 2QWGA 4BBWA 4FPHA 1A4GA 3K38A 4K1IA 4MWJA 2VW1A 1IVCA 1MZ5A 1B9VA 2HTWA 3CL0A 3SILA 2BATA 4YW3A 1SLIA 4GDIA 3H6JA 4B7JA 3TI3A 1IVGA 2YA8A 3D12A 2CMLA 4YZ2A 1Z4WA 2QWBA 1E8TA 1INWA 1WCSA 1MS5A 2YDTA 4H52A 4YZ5A 4YZ3A 4QN7A 4GZXA 1W8OA 4FP3A 2AGSA 4NN9A 2YA4A 4KS4A 1F8BA 5B2DA 3NN9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VK5 A;  4FPL A;  5HUG A;  1INV A;  3A71 A;  4MJU A;  3TI8 A;  1W8N A;  4J9T A;  3CL2 A;  1EUU A;  3W09 A;  1N1Y A;  4X47 A;  4GZP A;  2F10 A;  4HZZ A;  4MWR A;  2QWC A;  4MJV A;  2HTY A;  3TI6 A;  2QWF A;  4GZO A;  4WA4 A;  1INY A;  4B7R A;  4MZA A;  1A14 N;  1E8U A;  1NNC A;  4GJT A;  4YZ1 A;  4K1J A;  1W0P A;  4FVK A;  4YW2 A;  1NMA N;  4FPG A;  1NMB N;  4MWW A;  4XIL A;  4WEF A;  2HT5 A;  3SLI A;  2C4A A;  4MC7 A;  1DIM A;  3ALW A;  4FPF A;  3TIB A;  3O9J A;  5B2C A;  2VWD A;  4GZS A;  2F25 A;  4SLI A;  2VSK A;  1B9T A;  1W21 A;  2RKC A;  7NN9 A;  4XJW A;  3CYE A;  4GZT A;  3A72 A;  2W5N A;  4KS1 A;  2W20 A;  2HT7 A;  1INX A;  1KIT A;  4KS3 A;  2X9M A;  1F8E A;  4XIK A;  3K3A A;  5NN9 A;  4B7N A;  2VK6 A;  4YW5 A;  2QWD A;  4YW1 A;  4XJQ A;  1Z4Z A;  2SIM A;  4FPY A;  4XMA A;  1V0E A;  2VK7 A;  4FOY A;  1V3C A;  3NSS A;  4GB1 A;  4MWY A;  3TIA A;  1IVB A;  5F9T A;  4KS5 A;  2QWE A;  4B7Q A;  4HIZ A;  4XHX A;  2XZI A;  1N1T A;  1E8V A;  1IVE A;  1NNA A;  1SNT A;  1W20 A;  1A4Q A;  2F0Z A;  3OPZ A;  4H53 A;  3H73 A;  4FPE A;  6NN9 A;  3JU4 A;  2QWJ A;  1NCC N;  1L7H A;  2VW0 A;  3SAN A;  1NSD A;  1USR A;  1MR5 A;  3GVJ A;  3TI4 A;  3GVK A;  3TI5 A;  2F26 A;  4M4U A;  1NMC A;  5HUN A;  2SLI A;  3K39 A;  4XJZ A;  5HUM A;  3D11 A;  4D8S A;  1ING A;  4QN5 A;  2QWA A;  1VCU A;  2SIL A;  3INB A;  1DIL A;  4FOW A;  4X49 A;  4FJ6 A;  4XMI A;  4KS2 A;  2QWK A;  2BER A;  1MS9 A;  2HU4 A;  2YA7 A;  3K37 A;  4GEZ A;  1INH A;  4YZ4 A;  1V2I A;  4HZX A;  1N1V A;  2YA6 A;  5M1Z A;  4K3Y A;  1MWE A;  2VSM A;  4K1H A;  2XCY A;  1EUT A;  2B8H A;  4M3M A;  4XJ9 A;  4B7M A;  2HTR A;  1SLL A;  1Z4Y A;  2XZJ A;  4NC5 A;  5JYY A;  4MWX A;  4FOV A;  5HX0 A;  2AH2 A;  3K36 A;  4JF7 A;  2XZK A;  1L7G A;  2JKB A;  4DGR A;  4GDJ A;  1S0J A;  2HTU A;  2FHR A;  1W1X A;  4XJA A;  4I00 A;  4CPL A;  4Q6K A;  1IVF A;  3SAL A;  1INF A;  1MS4 A;  4CPZ A;  2ZB5 A;  2QWH A;  4WEG A;  2AEP A;  1WCQ A;  1MS1 A;  3H71 A;  3B7E A;  4CPN A;  1F8C A;  4XJR A;  4NCS A;  4QNP A;  1V0F A;  1Z50 A;  4FPO B;  1XOG A;  1IVD A;  4UF7 A;  4MZE A;  4XHB A;  4CPM A;  4QN6 A;  2F24 A;  4M4V A;  1NCA N;  4K1K A;  2F13 A;  1Z4X A;  1USX A;  4QN3 A;  1EUS A;  2BZD A;  4CPY A;  2F27 A;  4XE9 A;  1NSB A;  5HUK A;  1NNB A;  1MS8 A;  3CKZ A;  4MWU A;  2HTV A;  4HZW A;  4FP2 A;  4WA5 A;  4GZQ A;  2YDP A;  3T1E A;  4FPC A;  1SO7 A;  1N1S A;  3GVL A;  2YA5 A;  4FOQ A;  1NN2 A;  1VCJ A;  4MWV A;  3BEQ A;  1B9S A;  2ZB6 A;  4QN4 A;  2F28 A;  2W38 A;  1MS0 A;  2C4L A;  4HZY A;  1F8D A;  1MZ6 A;  2QWI A;  1XOE A;  4GZW A;  1V0Z A;  1NCD N;  1S0I A;  4XYX A;  2F11 A;  2VW2 A;  3H72 A;  4MX0 A;  4XJU A;  1NSC A;  1W0O A;  2VVZ A;  4XIO A;  4XJ8 A;  2W5O A;  3ALX A;  2HT8 A;  1Z4V A;  4FPK A;  3TIC A;  2A75 A;  1MS3 A;  4WA3 A;  3O9K A;  4CPO A;  1V3E A;  4X4A A;  2BF6 A;  1BJI A;  4YW4 A;  2F29 A;  1V3D A;  1EUR A;  2AEQ A;  4MWQ A;  3B69 A;  4XOG A;  2F12 A;  1L7F A;  2HU0 A;  3PJQ A;  4FZH A;  4M4N A;  4FQ4 A;  2HTQ A;  4HZV A;  4MWL A;  4X6K A;  1NCB N;  1V3B A;  4FPJ A;  2QWG A;  4BBW A;  4FPH A;  1A4G A;  3K38 A;  4K1I A;  4MWJ A;  2VW1 A;  1IVC A;  1MZ5 A;  1B9V A;  2HTW A;  3CL0 A;  3SIL A;  2BAT A;  4YW3 A;  1SLI A;  4GDI A;  3H6J A;  4B7J A;  3TI3 A;  1IVG A;  2YA8 A;  3D12 A;  2CML A;  4YZ2 A;  1Z4W A;  2QWB A;  1E8T A;  1INW A;  1WCS A;  1MS5 A;  2YDT A;  4H52 A;  4YZ5 A;  4YZ3 A;  4QN7 A;  4GZX A;  1W8O A;  4FP3 A;  2AGS A;  4NN9 A;  2YA4 A;  4KS4 A;  1F8B A;  5B2D A;  3NN9 A; 
#chains in the Genus database with same CATH topology
 2VK5 A;  4FPL A;  4UOU A;  5FWW A;  5HUG A;  3S2K A;  1INV A;  2IAT A;  3A9G A;  3A71 A;  4PWZ A;  3E5Z A;  4D4U A;  4MJU A;  3TI8 A;  1SUU A;  1W8N A;  4J9T A;  3CL2 A;  1EUU A;  3W09 A;  1N1Y A;  4X47 A;  1V04 A;  4GZP A;  3WW9 A;  2F10 A;  4HZZ A;  4MWR A;  4ASC A;  5GX3 A;  2QWC A;  3ZGC A;  4MJV A;  2HTY A;  3TI6 A;  3BYC A;  2QWF A;  4GZO A;  4WA4 A;  1INY A;  4B7R A;  4MZA A;  1A14 N;  2GVX A;  1E8U A;  1NNC A;  4GJT A;  3O4P A;  1N7D A;  4YZ1 A;  3SOQ A;  4K1J A;  1W0P A;  4FVK A;  2QE8 A;  4YW2 A;  1CVM A;  1NMA N;  4DG6 A;  4FPG A;  1NMB N;  5GX2 A;  4MWW A;  4XIL A;  2IAS A;  4WEF A;  2HT5 A;  3WDZ A;  2DYH A;  3SLI A;  2C4A A;  4MC7 A;  4AGT A;  1DIM A;  3ALW A;  4FPF A;  3TIB A;  3O9J A;  5B2C A;  4IFJ A;  4L7D A;  2FP8 A;  2H2U A;  1RWI A;  2VWD A;  3L6V A;  4GZS A;  4O5S A;  2F25 A;  4SLI A;  2VSK A;  1B9T A;  4GNB A;  1W21 A;  3Q6T A;  2RKC A;  2GVU A;  2VPJ A;  7NN9 A;  4HW6 A;  4XJW A;  3CYE A;  1S18 A;  4GZT A;  3A72 A;  4L7C A;  4Q1U A;  2W5N A;  4KS1 A;  2W20 A;  4AH4 A;  2HT7 A;  4CHB A;  2IAX A;  1INX A;  1KIT A;  4KS3 A;  2X9M A;  4L7B A;  1F8E A;  4N1B A;  4XIK A;  3K3A A;  5NN9 A;  4B7N A;  2VK6 A;  4A0P A;  4YW5 A;  2QWD A;  4YW1 A;  4XJQ A;  1Z4Z A;  2SIM A;  4FPY A;  4XMA A;  1V0E A;  2VK7 A;  4FOY A;  4IFN X;  1V3C A;  3NSS A;  4GB1 A;  4MWY A;  1ZGK A;  3TIA A;  2GVV A;  1IVB A;  5GX4 A;  2POO A;  2IVZ A;  3FVZ A;  5F9T A;  4KS5 A;  2QWE A;  2OJH A;  4B7Q A;  2IAV A;  4HIZ A;  2IAO A;  2WOZ A;  3S94 A;  1N6D A;  4XHX A;  2XZI A;  1N1T A;  1E8V A;  1IVE A;  3SOB B;  1NNA A;  1SNT A;  1W20 A;  1A4Q A;  2F0Z A;  3OPZ A;  1NPE A;  4H53 A;  3H73 A;  4FPE A;  6NN9 A;  3JU4 A;  2QWJ A;  1NCC N;  3FW0 A;  1L7H A;  2VW0 A;  5GX5 A;  3SAN A;  1NSD A;  1USR A;  1MR5 A;  3A9H A;  3GVJ A;  3TI4 A;  3GVK A;  3TI5 A;  2F26 A;  3HLI A;  4M4U A;  3ZGD A;  1NMC A;  5HUN A;  2SLI A;  3K39 A;  4XJZ A;  4CH9 A;  1C5K A;  5HUM A;  4YY8 A;  3D11 A;  4D8S A;  1ING A;  5D9C A;  3G4H A;  4QN5 A;  2QWA A;  1VCU A;  2SIL A;  3INB A;  1DIL A;  4D52 B;  4FOW A;  4X49 A;  4FJ6 A;  4XMI A;  4AHA A;  1S1D A;  4KS2 A;  2QWK A;  1CRU A;  2ZWA A;  2BER A;  1MS9 A;  2HU4 A;  4HHQ A;  4JML A;  2YA7 A;  2FP9 A;  4IN4 A;  1X2J A;  3K37 A;  4GEZ A;  1INH A;  5EO8 A;  4YZ4 A;  1V2I A;  4HZX A;  1N1V A;  2YA6 A;  5M1Z A;  3S8Z A;  4K3Y A;  1MWE A;  2VSM A;  4K1H A;  2XCY A;  1EUT A;  2B8H A;  4M3M A;  4XJ9 A;  1QLG A;  2GHS A;  4B7M A;  4XMB A;  3DR2 A;  5GTQ A;  2HTR A;  1CRZ A;  4GNA A;  3WWA A;  1SLL A;  1OFZ A;  3S8V A;  1Z4Y A;  2XZJ A;  4NC5 A;  4GN9 A;  5JYY A;  4MWX A;  4FOV A;  4C1Y A;  4AGI A;  3LI5 A;  1X2R A;  5HX0 A;  3U0S A;  4D52 C;  2AH2 A;  3K36 A;  3NO0 A;  1ZI0 A;  4JF7 A;  2W8B A;  2XZK A;  1QBI A;  1L7G A;  2DG0 A;  1CQ1 A;  2JKB A;  3SRG A;  4DGR A;  4GDJ A;  1S0J A;  2HTU A;  2FHR A;  1W1X A;  4XJA A;  2FLU X;  4I00 A;  4CPL A;  4Q6K A;  1IVF A;  3SAL A;  5FNS A;  1POO A;  1INF A;  1MS4 A;  4CPZ A;  2ZB5 A;  4IYG A;  2QWH A;  4WEG A;  2AEP A;  1WCQ A;  3IAX A;  1MS1 A;  3H71 A;  3B7E A;  4CSD A;  4CPN A;  4R40 A;  5D9B A;  1F8C A;  1C9U A;  4XJR A;  2ZZK A;  4NCS A;  4QNP A;  4GN8 A;  1V0F A;  1Z50 A;  3LI4 A;  4FPO B;  2IAQ A;  1XOG A;  1IVD A;  2IAP A;  4G3N A;  4UF7 A;  1H6L A;  4MZE A;  3Q6K A;  3HRP A;  4XHB A;  4CPM A;  4GN7 A;  4QN6 A;  3V1S A;  3LI3 A;  2F24 A;  4M4V A;  5EX7 A;  2VAQ A;  1NCA N;  4K1K A;  2F13 A;  1Z4X A;  2FPC A;  1USX A;  4QN3 A;  1EUS A;  2BZD A;  3AMS A;  5FZN A;  2XN4 A;  4CPY A;  2F27 A;  4XE9 A;  3V64 C;  1NSB A;  2DG1 A;  5EO7 A;  5HUK A;  1NNB A;  1MS8 A;  5FNQ A;  3I1C A;  3CKZ A;  4MWU A;  2IAU A;  2GVW A;  2HTV A;  2V91 A;  4IQK A;  4HZW A;  1WP5 A;  4FP2 A;  3P5B L;  4WA5 A;  3DAS A;  4GZQ A;  3WN7 A;  2YDP A;  3T1E A;  4FPC A;  4ZY3 A;  1SO7 A;  1RWL A;  3AMR A;  1N1S A;  4ZGC A;  4IFL X;  3GVL A;  2YA5 A;  4FOQ A;  1NN2 A;  5F72 C;  1VCJ A;  4MWV A;  3BEQ A;  1B9S A;  3ADE A;  2ZB6 A;  2ZW9 A;  4QN4 A;  5FNU A;  2F28 A;  2W38 A;  3TC9 A;  3VNH A;  1MS0 A;  2IAR A;  2H2N A;  5H47 A;  4HHO A;  2IAW A;  2C4L A;  4HZY A;  1F8D A;  5FNT A;  1MZ6 A;  2QWI A;  1XOE A;  3VNG A;  4GZW A;  1V0Z A;  1NCD N;  1S0I A;  4XYX A;  2F11 A;  2VW2 A;  1N6E A;  3H72 A;  4MX0 A;  4XJU A;  1NSC A;  1W0O A;  2VVZ A;  4XIO A;  4XJ8 A;  2W5O A;  3SRE A;  3ALX A;  2HT8 A;  1Z4V A;  3II7 A;  4FPK A;  3TIC A;  1E1A A;  1IJQ A;  3Q6P A;  2A75 A;  1MS3 A;  4WA3 A;  3O9K A;  5FZJ A;  1V3E A;  4CPO A;  4X4A A;  2BF6 A;  1BJI A;  4YW4 A;  3KGG A;  2F29 A;  1V3D A;  1EUR A;  2AEQ A;  4MWQ A;  3B69 A;  4XOG A;  2F12 A;  5D9D A;  1L7F A;  2HU0 A;  3PJQ A;  4FZH A;  1Q7F A;  3V65 B;  1N6F A;  4M4N A;  4FQ4 A;  5GX1 A;  2HTQ A;  1IUC A;  4HZV A;  4MWL A;  3UC1 A;  4X6K A;  3HLH A;  1NCB N;  1V3B A;  2ISM A;  4FPJ A;  2QWG A;  4BBW A;  4FPH A;  1A4G A;  3K38 A;  4K1I A;  4MWJ A;  4O5T A;  2VW1 A;  1IVC A;  1MZ5 A;  2HQS A;  1B9V A;  4D52 A;  2HTW A;  3CL0 A;  4C1Y B;  1K32 A;  2BAT A;  2P4O A;  4YW3 A;  3SIL A;  1SLI A;  4GDI A;  3SOV A;  3H6J A;  4B7J A;  2FPB A;  3TI3 A;  1IVG A;  2YA8 A;  3D12 A;  3G4E A;  2CML A;  2W8B B;  4YZ2 A;  5CGJ A;  1Z4W A;  2QWB A;  1E8T A;  1INW A;  2Z32 A;  5FNR A;  2G8S A;  4ZLR A;  1WCS A;  1MS5 A;  2YDT A;  4H52 A;  4YZ5 A;  4YZ3 A;  3KYA A;  4QN7 A;  4GZX A;  1W8O A;  4FP3 A;  4GNC A;  4IMB A;  1IUB A;  2AGS A;  4NN9 A;  1U6D X;  2YA4 A;  1PJX A;  4KS4 A;  2DSO A;  1F8B A;  5B2D A;  3NN9 A; 
#chains in the Genus database with same CATH homology
 2VK5 A;  4FPL A;  5HUG A;  1INV A;  3A71 A;  4MJU A;  3TI8 A;  1W8N A;  4J9T A;  3CL2 A;  1EUU A;  3W09 A;  1N1Y A;  4X47 A;  4GZP A;  2F10 A;  4HZZ A;  4MWR A;  2QWC A;  4MJV A;  2HTY A;  3TI6 A;  2QWF A;  4GZO A;  4WA4 A;  1INY A;  4B7R A;  4MZA A;  1A14 N;  1E8U A;  1NNC A;  4GJT A;  4YZ1 A;  4K1J A;  1W0P A;  4FVK A;  4YW2 A;  1NMA N;  4FPG A;  1NMB N;  4MWW A;  4XIL A;  4WEF A;  2HT5 A;  3SLI A;  2C4A A;  4MC7 A;  1DIM A;  3ALW A;  4FPF A;  3TIB A;  3O9J A;  5B2C A;  2H2U A;  2VWD A;  4GZS A;  2F25 A;  4SLI A;  2VSK A;  1B9T A;  1W21 A;  2RKC A;  7NN9 A;  4XJW A;  3CYE A;  1S18 A;  4GZT A;  3A72 A;  2W5N A;  4KS1 A;  2W20 A;  2HT7 A;  1INX A;  1KIT A;  4KS3 A;  2X9M A;  1F8E A;  4XIK A;  3K3A A;  5NN9 A;  4B7N A;  2VK6 A;  4YW5 A;  2QWD A;  4YW1 A;  4XJQ A;  1Z4Z A;  2SIM A;  4FPY A;  4XMA A;  1V0E A;  2VK7 A;  4FOY A;  1V3C A;  3NSS A;  4GB1 A;  4MWY A;  3TIA A;  1IVB A;  5F9T A;  4KS5 A;  2QWE A;  4B7Q A;  4HIZ A;  4XHX A;  2XZI A;  1N1T A;  1E8V A;  1IVE A;  1NNA A;  1SNT A;  1W20 A;  1A4Q A;  2F0Z A;  3OPZ A;  4H53 A;  3H73 A;  4FPE A;  6NN9 A;  3JU4 A;  2QWJ A;  1NCC N;  1L7H A;  2VW0 A;  3SAN A;  1NSD A;  1USR A;  1MR5 A;  3GVJ A;  3TI4 A;  3GVK A;  3TI5 A;  2F26 A;  4M4U A;  1NMC A;  5HUN A;  2SLI A;  3K39 A;  4XJZ A;  5HUM A;  3D11 A;  4D8S A;  1ING A;  4QN5 A;  2QWA A;  1VCU A;  2SIL A;  3INB A;  1DIL A;  4FOW A;  4X49 A;  4FJ6 A;  4XMI A;  1S1D A;  4KS2 A;  2QWK A;  2BER A;  1MS9 A;  2HU4 A;  2YA7 A;  3K37 A;  4GEZ A;  1INH A;  4YZ4 A;  1V2I A;  4HZX A;  1N1V A;  2YA6 A;  5M1Z A;  4K3Y A;  1MWE A;  2VSM A;  4K1H A;  2XCY A;  1EUT A;  2B8H A;  4M3M A;  4XJ9 A;  4B7M A;  2HTR A;  1SLL A;  1Z4Y A;  2XZJ A;  4NC5 A;  5JYY A;  4MWX A;  4FOV A;  5HX0 A;  2AH2 A;  3K36 A;  4JF7 A;  2XZK A;  1L7G A;  2JKB A;  4DGR A;  4GDJ A;  1S0J A;  2HTU A;  2FHR A;  1W1X A;  4XJA A;  4I00 A;  4CPL A;  4Q6K A;  1IVF A;  3SAL A;  1INF A;  1MS4 A;  4CPZ A;  2ZB5 A;  2QWH A;  4WEG A;  2AEP A;  1WCQ A;  1MS1 A;  3H71 A;  3B7E A;  4CPN A;  1F8C A;  4XJR A;  4NCS A;  4QNP A;  1V0F A;  1Z50 A;  4FPO B;  1XOG A;  1IVD A;  4UF7 A;  4MZE A;  4XHB A;  4CPM A;  4QN6 A;  2F24 A;  4M4V A;  1NCA N;  4K1K A;  2F13 A;  1Z4X A;  1USX A;  4QN3 A;  1EUS A;  2BZD A;  4CPY A;  2F27 A;  4XE9 A;  1NSB A;  5HUK A;  1NNB A;  1MS8 A;  3CKZ A;  4MWU A;  2HTV A;  4HZW A;  4FP2 A;  4WA5 A;  4GZQ A;  2YDP A;  3T1E A;  4FPC A;  1SO7 A;  1N1S A;  3GVL A;  2YA5 A;  4FOQ A;  1NN2 A;  1VCJ A;  4MWV A;  3BEQ A;  1B9S A;  2ZB6 A;  4QN4 A;  2F28 A;  2W38 A;  1MS0 A;  2H2N A;  2C4L A;  4HZY A;  1F8D A;  1MZ6 A;  2QWI A;  1XOE A;  4GZW A;  1V0Z A;  1NCD N;  1S0I A;  4XYX A;  2F11 A;  2VW2 A;  3H72 A;  4MX0 A;  4XJU A;  1NSC A;  1W0O A;  2VVZ A;  4XIO A;  4XJ8 A;  2W5O A;  3ALX A;  2HT8 A;  1Z4V A;  4FPK A;  3TIC A;  2A75 A;  1MS3 A;  4WA3 A;  3O9K A;  4CPO A;  1V3E A;  4X4A A;  2BF6 A;  1BJI A;  4YW4 A;  2F29 A;  1V3D A;  1EUR A;  2AEQ A;  4MWQ A;  3B69 A;  4XOG A;  2F12 A;  1L7F A;  2HU0 A;  3PJQ A;  4FZH A;  4M4N A;  4FQ4 A;  2HTQ A;  4HZV A;  4MWL A;  4X6K A;  1NCB N;  1V3B A;  4FPJ A;  2QWG A;  4BBW A;  4FPH A;  1A4G A;  3K38 A;  4K1I A;  4MWJ A;  2VW1 A;  1IVC A;  1MZ5 A;  1B9V A;  2HTW A;  3CL0 A;  3SIL A;  2BAT A;  4YW3 A;  1SLI A;  4GDI A;  3H6J A;  4B7J A;  3TI3 A;  1IVG A;  2YA8 A;  3D12 A;  2CML A;  4YZ2 A;  1Z4W A;  2QWB A;  1E8T A;  1INW A;  1WCS A;  1MS5 A;  2YDT A;  4H52 A;  4YZ5 A;  4YZ3 A;  4QN7 A;  4GZX A;  1W8O A;  4FP3 A;  2AGS A;  4NN9 A;  2YA4 A;  4KS4 A;  1F8B A;  5B2D A;  3NN9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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